Geir Slupphaug - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Schwarz SD, Xu J, Gunasekera K, Schürmann D, Vågbø CB, Ferrari E, Slupphaug G, Hottiger MO, Schär P, Steinacher R. Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature Communications. 15: 184. PMID 38167803 DOI: 10.1038/s41467-023-44209-8  0.549
2023 Hayran AB, Liabakk NB, Aas PA, Kusnierczyk A, Vågbø CB, Sarno A, Iveland TS, Chawla K, Zahn A, Di Noia JM, Slupphaug G, Kavli B. RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork. Nucleic Acids Research. PMID 38000394 DOI: 10.1093/nar/gkad1115  0.346
2021 Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, ... ... Slupphaug G, et al. NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology. 4: 1354. PMID 34857879 DOI: 10.1038/s42003-021-02864-x  0.379
2021 Olinski R, Slupphaug G, Foksinski M, Krokan HE. Genomic Uracil and Aberrant Profile of Demethylation Intermediates in Epigenetics and Hematologic Malignancies. International Journal of Molecular Sciences. 22. PMID 33921666 DOI: 10.3390/ijms22084212  0.462
2021 Kavli B, Iveland TS, Buchinger E, Hagen L, Liabakk NB, Aas PA, Obermann TS, Aachmann FL, Slupphaug G. RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork. Nucleic Acids Research. PMID 33784377 DOI: 10.1093/nar/gkab195  0.455
2020 Vågbø CB, Slupphaug G. RNA in DNA repair. Dna Repair. 95: 102927. PMID 32920299 DOI: 10.1016/J.Dnarep.2020.102927  0.511
2020 Eldin P, Péron S, Galashevskaya A, Denis-Lagache N, Cogné M, Slupphaug G, Briant L. Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination. Journal of Translational Medicine. 18: 310. PMID 32778120 DOI: 10.1186/S12967-020-02478-7  0.436
2019 Steinacher R, Barekati Z, Botev P, Kuśnierczyk A, Slupphaug G, Schär P. SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation. The Embo Journal. 38. PMID 30523148 DOI: 10.15252/Embj.201899242  0.598
2018 Phuyal S, Kasem M, Knittelfelder O, Sharma A, Fonseca DM, Vebraite V, Shaposhnikov S, Slupphaug G, Skaug V, Zienolddiny S. Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes. Nanotoxicology. 1-15. PMID 29350075 DOI: 10.1080/17435390.2018.1425500  0.306
2017 Brickner JR, Soll JM, Lombardi PM, Vågbø CB, Mudge MC, Oyeniran C, Rabe R, Jackson J, Sullender ME, Blazosky E, Byrum AK, Zhao Y, Corbett MA, Gécz J, Field M, ... ... Slupphaug G, et al. A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 551: 389-393. PMID 29144457 DOI: 10.1038/Nature24484  0.546
2017 Buchinger E, Wiik SÅ, Kusnierczyk A, Rabe R, Aas PA, Kavli B, Slupphaug G, Aachmann FL. Backbone (1)H, (13)C and (15)N chemical shift assignment of full-length human uracil DNA glycosylase UNG2. Biomolecular Nmr Assignments. PMID 28879561 DOI: 10.1007/S12104-017-9772-5  0.324
2017 Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M. No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice. Scientific Reports. 7: 4384. PMID 28663564 DOI: 10.1038/S41598-017-04472-4  0.555
2017 Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JD, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, et al. NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell Reports. 18: 82-92. PMID 28052262 DOI: 10.1016/J.Celrep.2016.12.009  0.302
2016 Rydning SL, Backe PH, Sousa MM, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK. Novel UCHL1 mutations reveal new insights into ubiquitin processing. Human Molecular Genetics. PMID 28007905 DOI: 10.1093/Hmg/Ddw391  0.318
2016 Skarpengland T, Dahl TB, Skjelland M, Scheffler K, Sousa MM, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, et al. Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA. Free Radical Biology & Medicine. PMID 27381496 DOI: 10.1016/J.Freeradbiomed.2016.07.001  0.55
2016 Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, ... ... Slupphaug G, et al. Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Scientific Reports. 6: 28337. PMID 27328939 DOI: 10.1038/Srep28337  0.457
2016 Helander L, Sharma A, Krokan HE, Plaetzer K, Krammer B, Tortik N, Gederaas OA, Slupphaug G, Hagen L. Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins. Molecular Biosystems. 12: 796-805. PMID 26742548 DOI: 10.1039/C5Mb00744E  0.308
2015 Bjørge MD, Hildrestrand GA, Scheffler K, Suganthan R, Rolseth V, Kuśnierczyk A, Rowe AD, Vågbø CB, Vetlesen S, Eide L, Slupphaug G, Nakabeppu Y, Bredy TW, Klungland A, Bjørås M. Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice. Cell Reports. 13: 2671-8. PMID 26711335 DOI: 10.1016/J.Celrep.2015.12.001  0.397
2015 Mjelle R, Hegre SA, Aas PA, Slupphaug G, Drabløs F, Saetrom P, Krokan HE. Cell cycle regulation of human DNA repair and chromatin remodeling genes. Dna Repair. 30: 53-67. PMID 25881042 DOI: 10.1016/J.Dnarep.2015.03.007  0.484
2015 Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, Visnes T, Aas PA, Liabakk NB, Slupphaug G, Sætrom P, Kavli B, Krokan HE. AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. Dna Repair. 25: 60-71. PMID 25486549 DOI: 10.1016/J.Dnarep.2014.11.006  0.391
2015 Hagen L, Sharma A, Aas PA, Slupphaug G. Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection. Biochimica Et Biophysica Acta. 1854: 84-90. PMID 25448019 DOI: 10.1016/J.Bbapap.2014.10.016  0.319
2014 Krokan HE, Sætrom P, Aas PA, Pettersen HS, Kavli B, Slupphaug G. Error-free versus mutagenic processing of genomic uracil--relevance to cancer. Dna Repair. 19: 38-47. PMID 24746924 DOI: 10.1016/J.Dnarep.2014.03.028  0.456
2013 Galashevskaya A, Sarno A, Vågbø CB, Aas PA, Hagen L, Slupphaug G, Krokan HE. A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported. Dna Repair. 12: 699-706. PMID 23742752 DOI: 10.1016/J.Dnarep.2013.05.002  0.369
2013 Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G. An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. Plos One. 8: e55493. PMID 23405159 DOI: 10.1371/Journal.Pone.0055493  0.553
2013 Hu Y, Ericsson I, Torseth K, Methot SP, Sundheim O, Liabakk NB, Slupphaug G, Di Noia JM, Krokan HE, Kavli B. A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching. Journal of Molecular Biology. 425: 424-43. PMID 23183374 DOI: 10.1016/J.Jmb.2012.11.026  0.447
2012 Torseth K, Doseth B, Hagen L, Olaisen C, Liabakk NB, Græsmann H, Durandy A, Otterlei M, Krokan HE, Kavli B, Slupphaug G. The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA. Dna Repair. 11: 559-69. PMID 22521144 DOI: 10.1016/J.Dnarep.2012.03.006  0.523
2012 Roberts VA, Pique ME, Hsu S, Li S, Slupphaug G, Rambo RP, Jamison JW, Liu T, Lee JH, Tainer JA, Ten Eyck LF, Woods VL. Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase. Nucleic Acids Research. 40: 6070-81. PMID 22492624 DOI: 10.1093/Nar/Gks291  0.72
2012 Doseth B, Ekre C, Slupphaug G, Krokan HE, Kavli B. Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil. Dna Repair. 11: 587-93. PMID 22483865 DOI: 10.1016/J.Dnarep.2012.03.003  0.582
2012 Wollen Steen K, Doseth B, P. Westbye M, Akbari M, Kang D, Falkenberg M, Slupphaug G. MtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored Dna Repair. 11: 82-91. PMID 22153281 DOI: 10.1016/J.Dnarep.2011.10.026  0.63
2011 Hanssen-Bauer A, Solvang-Garten K, Sundheim O, Peña-Diaz J, Andersen S, Slupphaug G, Krokan HE, Wilson DM, Akbari M, Otterlei M. XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. Environmental and Molecular Mutagenesis. 52: 623-35. PMID 21786338 DOI: 10.1002/Em.20663  0.584
2011 Pettersen HS, Visnes T, Vågbø CB, Svaasand EK, Doseth B, Slupphaug G, Kavli B, Krokan HE. UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. Nucleic Acids Research. 39: 8430-44. PMID 21745813 DOI: 10.1093/Nar/Gkr563  0.592
2011 Doseth B, Visnes T, Wallenius A, Ericsson I, Sarno A, Pettersen HS, Flatberg A, Catterall T, Slupphaug G, Krokan HE, Kavli B. Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse. The Journal of Biological Chemistry. 286: 16669-80. PMID 21454529 DOI: 10.1074/Jbc.M111.230052  0.564
2011 Baglo Y, Sousa MM, Slupphaug G, Hagen L, Håvåg S, Helander L, Zub KA, Krokan HE, Gederaas OA. Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 10: 1137-45. PMID 21448498 DOI: 10.1039/C0Pp00369G  0.349
2011 Zeitlin SG, Chapados BR, Baker NM, Tai C, Slupphaug G, Wang JY. Uracil DNA N-glycosylase promotes assembly of human centromere protein A. Plos One. 6: e17151. PMID 21399697 DOI: 10.1371/Journal.Pone.0017151  0.793
2010 Monsen VT, Sundheim O, Aas PA, Westbye MP, Sousa MM, Slupphaug G, Krokan HE. Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3. Nucleic Acids Research. 38: 6447-55. PMID 20525795 DOI: 10.1093/Nar/Gkq518  0.493
2010 Krokan HE, Kavli B, Otterlei M, Akbari M, Slupphaug G, Aas PA. 22 DNA repair and cancer Ejc Supplements. 8: 7. DOI: 10.1016/S1359-6349(10)70831-4  0.483
2009 Gilljam KM, Feyzi E, Aas PA, Sousa MM, Müller R, Vågbø CB, Catterall TC, Liabakk NB, Slupphaug G, Drabløs F, Krokan HE, Otterlei M. Identification of a novel, widespread, and functionally important PCNA-binding motif. The Journal of Cell Biology. 186: 645-54. PMID 19736315 DOI: 10.1083/Jcb.200903138  0.486
2009 Knaevelsrud I, Slupphaug G, Leiros I, Matsuda A, Ruoff P, Bjelland S. Opposite-base dependent excision of 5-formyluracil from DNA by hSMUG1. International Journal of Radiation Biology. 85: 413-20. PMID 19365746 DOI: 10.1080/09553000902818915  0.602
2009 Visnes T, Doseth B, Pettersen HS, Hagen L, Sousa MM, Akbari M, Otterlei M, Kavli B, Slupphaug G, Krokan HE. Uracil in DNA and its processing by different DNA glycosylases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 563-8. PMID 19008197 DOI: 10.1098/Rstb.2008.0186  0.582
2008 Sundheim O, Talstad VA, Vågbø CB, Slupphaug G, Krokan HE. AlkB demethylases flip out in different ways. Dna Repair. 7: 1916-23. PMID 18723127 DOI: 10.1016/J.Dnarep.2008.07.015  0.621
2008 Visnes T, Akbari M, Hagen L, Slupphaug G, Krokan HE. The rate of base excision repair of uracil is controlled by the initiating glycosylase. Dna Repair. 7: 1869-81. PMID 18721906 DOI: 10.1016/J.Dnarep.2008.07.012  0.54
2008 Westbye MP, Feyzi E, Aas PA, Vågbø CB, Talstad VA, Kavli B, Hagen L, Sundheim O, Akbari M, Liabakk NB, Slupphaug G, Otterlei M, Krokan HE. Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. The Journal of Biological Chemistry. 283: 25046-56. PMID 18603530 DOI: 10.1074/Jbc.M803776200  0.521
2008 Hagen L, Kavli B, Sousa MM, Torseth K, Liabakk NB, Sundheim O, Pena-Diaz J, Otterlei M, Hørning O, Jensen ON, Krokan HE, Slupphaug G. Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA. The Embo Journal. 27: 51-61. PMID 18079698 DOI: 10.1038/Sj.Emboj.7601958  0.405
2007 Feyzi E, Sundheim O, Westbye MP, Aas PA, Vågbø CB, Otterlei M, Slupphaug G, Krokan HE. RNA base damage and repair. Current Pharmaceutical Biotechnology. 8: 326-31. PMID 18289040 DOI: 10.2174/138920107783018363  0.404
2007 Sousa MM, Krokan HE, Slupphaug G. DNA-uracil and human pathology. Molecular Aspects of Medicine. 28: 276-306. PMID 17590428 DOI: 10.1016/J.Mam.2007.04.006  0.604
2007 Pettersen HS, Sundheim O, Gilljam KM, Slupphaug G, Krokan HE, Kavli B. Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms. Nucleic Acids Research. 35: 3879-92. PMID 17537817 DOI: 10.1093/Nar/Gkm372  0.57
2007 Parsons JL, Kavli B, Slupphaug G, Dianov GL. NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break. Biochemistry. 46: 4158-63. PMID 17348689 DOI: 10.1021/Bi0622569  0.586
2007 Kavli B, Otterlei M, Slupphaug G, Krokan HE. Uracil in DNA--general mutagen, but normal intermediate in acquired immunity. Dna Repair. 6: 505-16. PMID 17116429 DOI: 10.1016/J.Dnarep.2006.10.014  0.537
2007 Lu CC, Huang HT, Wang JT, Slupphaug G, Li TK, Wu MC, Chen YC, Lee CP, Chen MR. Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication. Journal of Virology. 81: 1195-208. PMID 17108049 DOI: 10.1128/Jvi.01518-06  0.616
2006 Hagen L, Peña-Diaz J, Kavli B, Otterlei M, Slupphaug G, Krokan HE. Genomic uracil and human disease. Experimental Cell Research. 312: 2666-72. PMID 16860315 DOI: 10.1016/J.Yexcr.2006.06.015  0.532
2006 Sundheim O, Vågbø CB, Bjørås M, Sousa MML, Talstad V, Aas PA, Drabløs F, Krokan HE, Tainer JA, Slupphaug G. Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage Embo Journal. 25: 3389-3397. PMID 16858410 DOI: 10.1038/Sj.Emboj.7601219  0.632
2005 Kavli B, Andersen S, Otterlei M, Liabakk NB, Imai K, Fischer A, Durandy A, Krokan HE, Slupphaug G. B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil. The Journal of Experimental Medicine. 201: 2011-21. PMID 15967827 DOI: 10.1084/Jem.20050042  0.559
2005 Zeitlin SG, Patel S, Kavli B, Slupphaug G. Xenopus CENP-A assembly into chromatin requires base excision repair proteins. Dna Repair. 4: 760-72. PMID 15964249 DOI: 10.1016/J.Dnarep.2005.02.007  0.537
2004 Akbari M, Otterlei M, Peña-Diaz J, Aas PA, Kavli B, Liabakk NB, Hagen L, Imai K, Durandy A, Slupphaug G, Krokan HE. Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Research. 32: 5486-98. PMID 15479784 DOI: 10.1093/Nar/Gkh872  0.485
2004 Drabløs F, Feyzi E, Aas PA, Vaagbø CB, Kavli B, Bratlie MS, Peña-Diaz J, Otterlei M, Slupphaug G, Krokan HE. Alkylation damage in DNA and RNA--repair mechanisms and medical significance. Dna Repair. 3: 1389-407. PMID 15380096 DOI: 10.1016/J.Dnarep.2004.05.004  0.495
2004 Peña-Diaz J, Akbari M, Sundheim O, Farez-Vidal ME, Andersen S, Sneve R, Gonzalez-Pacanowska D, Krokan HE, Slupphaug G. Trypanosoma cruzi contains a single detectable uracil-DNA glycosylase and repairs uracil exclusively via short patch base excision repair. Journal of Molecular Biology. 342: 787-99. PMID 15342237 DOI: 10.1016/J.Jmb.2004.07.043  0.6
2004 Krokan HE, Kavli B, Slupphaug G. Novel aspects of macromolecular repair and relationship to human disease. Journal of Molecular Medicine (Berlin, Germany). 82: 280-97. PMID 14985856 DOI: 10.1007/S00109-004-0528-1  0.547
2003 Slupphaug G, Kavli B, Krokan HE. The interacting pathways for prevention and repair of oxidative DNA damage. Mutation Research. 531: 231-51. PMID 14637258 DOI: 10.1016/J.Mrfmmm.2003.06.002  0.559
2003 Imai K, Slupphaug G, Lee WI, Revy P, Nonoyama S, Catalan N, Yel L, Forveille M, Kavli B, Krokan HE, Ochs HD, Fischer A, Durandy A. Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nature Immunology. 4: 1023-8. PMID 12958596 DOI: 10.1038/Ni974  0.525
2003 Aas PA, Otterlei M, Falnes PO, Vågbø CB, Skorpen F, Akbari M, Sundheim O, Bjørås M, Slupphaug G, Seeberg E, Krokan HE. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature. 421: 859-63. PMID 12594517 DOI: 10.1038/Nature01363  0.538
2002 Krokan HE, Drabløs F, Slupphaug G. Uracil in DNA--occurrence, consequences and repair. Oncogene. 21: 8935-48. PMID 12483510 DOI: 10.1038/Sj.Onc.1205996  0.605
2002 Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE, Slupphaug G. hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup. The Journal of Biological Chemistry. 277: 39926-36. PMID 12161446 DOI: 10.1074/Jbc.M207107200  0.525
2001 Krokan HE, Otterlei M, Nilsen H, Kavli B, Skorpen F, Andersen S, Skjelbred C, Akbari M, Aas PA, Slupphaug G. Properties and functions of human uracil-DNA glycosylase from the UNG gene Progress in Nucleic Acid Research and Molecular Biology. 68: 365-386. PMID 11554311 DOI: 10.1016/S0079-6603(01)68112-1  0.57
2001 Cappelli E, Hazra T, Hill JW, Slupphaug G, Bogliolo M, Frosina G. Rates of base excision repair are not solely dependent on levels of initiating enzymes. Carcinogenesis. 22: 387-93. PMID 11238177 DOI: 10.1093/Carcin/22.3.387  0.492
2000 Nilsen H, Rosewell I, Robins P, Skjelbred CF, Andersen S, Slupphaug G, Daly G, Krokan HE, Lindahl T, Barnes DE. Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication Molecular Cell. 5: 1059-1065. PMID 10912000 DOI: 10.1016/S1097-2765(00)80271-3  0.575
2000 Krokan HE, Nilsen H, Skorpen F, Otterlei M, Slupphaug G. Base excision repair of DNA in mammalian cells Febs Letters. 476: 73-77. PMID 10878254 DOI: 10.1016/S0014-5793(00)01674-4  0.605
2000 Nilsen H, Steinsbekk KS, Otterlei M, Slupphaug G, Aas PA, Krokan HE. Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues Nucleic Acids Research. 28: 2277-2285. PMID 10871356 DOI: 10.1093/Nar/28.12.2277  0.462
2000 Parikh SS, Walcher G, Jones GD, Slupphaug G, Krokan HE, Blackburn GM, Tainer JA. Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects. Proceedings of the National Academy of Sciences of the United States of America. 97: 5083-8. PMID 10805771 DOI: 10.1073/Pnas.97.10.5083  0.786
1999 Otterlei M, Warbrick E, Nagelhus TA, Haug T, Slupphaug G, Akbari M, Aas PA, Steinsbekk K, Bakke O, Krokan HE. Post-replicative base excision repair in replication foci. The Embo Journal. 18: 3834-3844. PMID 10393198 DOI: 10.1093/Emboj/18.13.3834  0.55
1998 Bharati S, Krokan HE, Kristiansen L, Otterlei M, Slupphaug G. Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites Nucleic Acids Research. 26: 4953-4959. PMID 9776759 DOI: 10.1093/Nar/26.21.4953  0.426
1998 Otterlei M, Haug T, Nagelhus TA, Slupphaug G, Lindmo T, Krokan HE. Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively Nucleic Acids Research. 26: 4611-4617. PMID 9753728 DOI: 10.1093/Nar/26.20.4611  0.373
1998 Parikh SS, Mol CD, Slupphaug G, Bharati S, Krokan HE, Tainer JA. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. The Embo Journal. 17: 5214-26. PMID 9724657 DOI: 10.1093/Emboj/17.17.5214  0.805
1997 Krokan HE, Standal R, Slupphaug G. DNA glycosylases in the base excision repair of DNA Biochemical Journal. 325: 1-16. PMID 9224623 DOI: 10.1042/Bj3250001  0.643
1996 Nagelhus TA, Slupphaug G, Krokan HE, Lindmo T. Fading correction for fluorescence quantitation in confocal microscopy. Cytometry. 23: 187-195. PMID 8974864 DOI: 10.1002/(Sici)1097-0320(19960301)23:3<187::Aid-Cyto2>3.0.Co;2-G  0.334
1996 Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE, Tainer JA. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature. 384: 87-92. PMID 8900285 DOI: 10.1038/384087A0  0.818
1996 Dizdaroglu M, Karakaya A, Jaruga P, Slupphaug G, Krokan HE. Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage. Nucleic Acids Research. 24: 418-22. PMID 8602352 DOI: 10.1093/Nar/24.3.418  0.615
1996 Bouhamdan M, Benichou S, Rey F, Navarro JM, Agostini I, Spire B, Camonis J, Slupphaug G, Vigne R, Benarous R, Sire J. Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme. Journal of Virology. 70: 697-704. PMID 8551605 DOI: 10.1128/Jvi.70.2.697-704.1996  0.517
1996 Mol CD, Slupphaug G, Arvai AS, Tainer JA, Kavli B, Krokan HE. Structural basis for the removal and exclusion of uracil from DNA Acta Crystallographica Section a Foundations of Crystallography. 52: C157-C158. DOI: 10.1107/S010876739609294X  0.792
1996 Kavli B, Slupphaug G, Mol CD, Arvai AS, Peterson SB, Tainer JA, Krokan HE. Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase. The Embo Journal. 15: 3442-3447. DOI: 10.1002/J.1460-2075.1996.Tb00710.X  0.813
1995 Slupphaug G, Eftedal I, Kavli B, Bharati S, Helle NM, Haug T, Levine DW, Krokan HE. Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. Biochemistry. 34: 128-138. PMID 7819187 DOI: 10.1021/Bi00001A016  0.554
1995 Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA. Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis. Cell. 80: 869-78. PMID 7697717 DOI: 10.1016/0092-8674(95)90290-2  0.792
1995 Mol CD, Arvai AS, Sanderson RJ, Slupphaug G, Kavli B, Krokan HE, Mosbaugh DW, Tainer JA. Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. Cell. 82: 701-8. PMID 7671300 DOI: 10.1016/0092-8674(95)90467-0  0.806
1995 Nagelhus TA, Slupphaug G, Lindmo T, Krokan HE. Cell cycle regulation and subcellular localization of the major human uracil-DNA glycosylase. Experimental Cell Research. 220: 292-297. PMID 7556436 DOI: 10.1006/Excr.1995.1318  0.458
1993 Eftedal I, Guddal PH, Slupphaug G, Volden G, Krokan HE. Consensus sequences for good and poor removal of uracil from double stranded DNA by uracil-DNA glycosylase Nucleic Acids Research. 21: 2095-2101. PMID 8502549 DOI: 10.1093/Nar/21.9.2095  0.568
1993 Slupphaug G, Markussen FH, Olsen LC, Aasland R, Aarsaether N, Bakke O, Krokan HE, Helland DE. Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene Nucleic Acids Research. 21: 2579-2584. PMID 8332455 DOI: 10.1093/Nar/21.11.2579  0.384
1993 Slupphaug G, Alseth I, Eftedal I, Volden G, Krokan HE. Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplifications Analytical Biochemistry. 211: 164-169. PMID 8323030 DOI: 10.1006/Abio.1993.1248  0.599
1992 Slupphaug G, Lettrem I, Myrnes B, Krokan HE. Expression of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase in human placentae from smokers and non-smokers Carcinogenesis. 13: 1769-1773. PMID 1423836 DOI: 10.1093/Carcin/13.10.1769  0.473
1991 Slupphaug G, OIsen LC, Helland D, Aasland R, Krokan HE. Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil-DNA glycosylase Nucleic Acids Research. 19: 5131-5137. PMID 1923798 DOI: 10.1093/Nar/19.19.5131  0.483
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