☰

Andrew Bennet, Ph.D. - Publications

Affiliations: 
Chemistry Simon Fraser University, Burnaby, British Columbia, Canada 
Area:
Bioorganic chemistry, carbohydrate chemistry, physical organic chemistry
Website:
https://www.sfu.ca/chemistry/people/profiles/bennet.html
Tree Info Similar researchers PubMed Report error

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ren W, Farren-Dai M, Sannikova N, Świderek K, Wang Y, Akintola O, Britton R, Moliner V, Bennet AJ. Glycoside hydrolase stabilization of transition state charge: new directions for inhibitor design. Chemical Science. 11: 10488-10495. PMID 34094307 DOI: 10.1039/d0sc04401f  0.314
2020 Nejatie A, Akintola O, Steves E, Shamsi Kazem Abadi S, Moore MM, Bennet AJ. Structurally homologous sialidases exhibit a commonality in reactivity: Glycoside hydrolase-catalyzed hydrolysis of Kdn-thioglycosides. Bioorganic Chemistry. 104484. PMID 33268005 DOI: 10.1016/j.bioorg.2020.104484  0.393
2020 Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, ... Bennet AJ, et al. An Epoxide Intermediate in Glycosidase Catalysis. Acs Central Science. 6: 760-770. PMID 32490192 DOI: 10.1021/Acscentsci.0C00111  0.413
2020 Adabala PJP, Shamsi Kazem Abadi S, Akintola O, Bhosale S, Bennet AJ. Conformationally Controlled Reactivity of Carbasugars Uncovers the Choreography of Glycoside Hydrolase Catalysis. The Journal of Organic Chemistry. 85: 3336-3348. PMID 31994882 DOI: 10.1021/acs.joc.9b03152  0.363
2019 Abadi SSK, Deen MC, Watson JN, Shidmoossavee FS, Bennet AJ. Directed Evolution of a Remarkably Efficient Kdnase from a Bacterial Neuraminidase. Glycobiology. PMID 31804700 DOI: 10.1093/glycob/cwz099  0.319
2018 Sannikova N, Gerak CAN, Shidmoossavee FS, King DT, Shamsi Kazem Abadi S, Lewis AR, Bennet AJ. Both Chemical and Non-Chemical Steps Limit the Catalytic Efficiency of Family 4 Glycoside Hydrolases. Biochemistry. PMID 29630821 DOI: 10.1021/acs.biochem.8b00117  0.429
2016 Speciale G, Farren-Dai M, Shidmoossavee FS, Williams SJ, Bennet AJ. C2-Oxyanion neighboring group participation: Transition state structure for the hydroxide-promoted hydrolysis of 4-nitrophenyl α-D-mannopyranoside. Journal of the American Chemical Society. PMID 27723312 DOI: 10.1021/Jacs.6B07935  0.419
2014 Chan J, Sannikova N, Tang A, Bennet AJ. Transition-state structure for the quintessential SN2 reaction of a carbohydrate: reaction of α-glucopyranosyl fluoride with azide ion in water. Journal of the American Chemical Society. 136: 12225-8. PMID 25121958 DOI: 10.1021/ja506092h  0.511
2014 Cheng LL, Shidmoossavee FS, Bennet AJ. Neuraminidase substrate promiscuity permits a mutant Micromonospora viridifaciens enzyme to synthesize artificial carbohydrates. Biochemistry. 53: 3982-89. PMID 24870444 DOI: 10.1021/bi500203p  0.349
2013 Yeung JH, Telford JC, Shidmoossavee FS, Bennet AJ, Taylor GL, Moore MM. Kinetic and structural evaluation of selected active site mutants of the Aspergillus fumigatus KDNase (sialidase). Biochemistry. 52: 9177-86. PMID 24295366 DOI: 10.1021/Bi401166F  0.327
2012 Bennet AJ. Kinetic isotope effects for studying post-translational modifying enzymes. Current Opinion in Chemical Biology. 16: 472-8. PMID 23146439 DOI: 10.1016/j.cbpa.2012.10.024  0.345
2012 Macauley MS, Chan J, Zandberg WF, He Y, Whitworth GE, Stubbs KA, Yuzwa SA, Bennet AJ, Varki A, Davies GJ, Vocadlo DJ. Metabolism of vertebrate amino sugars with N-glycolyl groups: intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc, and the biochemical and structural rationale for the substrate tolerance of β-O-linked β-N-acetylglucosaminidase. The Journal of Biological Chemistry. 287: 28882-97. PMID 22692202 DOI: 10.1074/Jbc.M112.363721  0.391
2012 Chan J, Lewis AR, Indurugalla D, Schur M, Wakarchuk W, Bennet AJ. Transition state analysis of Vibrio cholerae sialidase-catalyzed hydrolyses of natural substrate analogues. Journal of the American Chemical Society. 134: 3748-57. PMID 22296330 DOI: 10.1021/Ja208564Y  0.555
2012 Chan J, Tang A, Bennet AJ. A stepwise solvent-promoted SNi reaction of α-D-glucopyranosyl fluoride: mechanistic implications for retaining glycosyltransferases. Journal of the American Chemical Society. 134: 1212-20. PMID 22148388 DOI: 10.1021/Ja209339J  0.538
2012 Chan J, Watson JN, Lu A, Cerda VC, Borgford TJ, Bennet AJ. Bacterial and viral sialidases: contribution of the conserved active site glutamate to catalysis. Biochemistry. 51: 433-41. PMID 22133027 DOI: 10.1021/Bi201019N  0.478
2011 Chan J, Sandhu G, Bennet AJ. A mechanistic study of sialic acid mutarotation: implications for mutarotase enzymes. Organic & Biomolecular Chemistry. 9: 4818-22. PMID 21584336 DOI: 10.1039/c1ob05079f  0.532
2011 Chakladar S, Cheng L, Choi M, Liu J, Bennet AJ. Mechanistic evaluation of MelA α-galactosidase from Citrobacter freundii: a family 4 glycosyl hydrolase in which oxidation is rate-limiting. Biochemistry. 50: 4298-308. PMID 21495656 DOI: 10.1021/bi101808h  0.452
2011 Chan J, Lu A, Bennet AJ. Turnover is rate-limited by deglycosylation for Micromonospora viridifaciens sialidase-catalyzed hydrolyses: conformational implications for the Michaelis complex. Journal of the American Chemical Society. 133: 2989-97. PMID 21322554 DOI: 10.1021/ja109199p  0.544
2011 Telford JC, Yeung JH, Xu G, Kiefel MJ, Watts AG, Hader S, Chan J, Bennet AJ, Moore MM, Taylor GL. The Aspergillus fumigatus sialidase is a 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase (KDNase): structural and mechanistic insights. The Journal of Biological Chemistry. 286: 10783-92. PMID 21247893 DOI: 10.1074/Jbc.M110.207043  0.471
2010 Shidmoossavee FS, Cheng L, Watson JN, Bennet AJ. Brønsted analysis of an enzyme-catalyzed pseudo-deglycosylation reaction: mechanism of desialylation in sialidases. Biochemistry. 49: 6473-84. PMID 20575524 DOI: 10.1021/bi100513u  0.4
2010 Chan J, Lewis AR, Gilbert M, Karwaski MF, Bennet AJ. A direct NMR method for the measurement of competitive kinetic isotope effects. Nature Chemical Biology. 6: 405-7. PMID 20418878 DOI: 10.1038/Nchembio.352  0.514
2006 Narine AA, Watson JN, Bennet AJ. Mechanistic requirements for the efficient enzyme-catalyzed hydrolysis of thiosialosides. Biochemistry. 45: 9319-26. PMID 16866378 DOI: 10.1021/bi0607507  0.369
2006 Lewis BE, Choytun N, Schramm VL, Bennet AJ. Transition states for glucopyranose interconversion Journal of the American Chemical Society. 128: 5049-5058. PMID 16608339 DOI: 10.1021/Ja0573054  0.308
2005 Watson JN, Newstead S, Narine AA, Taylor G, Bennet AJ. Two nucleophilic mutants of the Micromonospora viridifaciens sialidase operate with retention of configuration by two different mechanisms. Chembiochem : a European Journal of Chemical Biology. 6: 1999-2004. PMID 16206228 DOI: 10.1002/Cbic.200500114  0.319
2005 Newstead S, Watson JN, Knoll TL, Bennet AJ, Taylor G. Structure and mechanism of action of an inverting mutant sialidase. Biochemistry. 44: 9117-22. PMID 15966735 DOI: 10.1021/Bi050517T  0.401
2005 Dookhun V, Bennet AJ. Unexpected stability of aryl beta-N-acetylneuraminides in neutral solution: biological implications for sialyl transfer reactions. Journal of the American Chemical Society. 127: 7458-65. PMID 15898795 DOI: 10.1021/ja042280e  0.307
2005 Watson JN, Knoll TL, Chen JH, Chou DT, Borgford TJ, Bennet AJ. Use of conformationally restricted pyridinium alpha-D-N-acetylneuraminides to probe specificity in bacterial and viral sialidases. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 83: 115-22. PMID 15864320 DOI: 10.1139/O04-126  0.307
2004 Watson JN, Newstead S, Dookhun V, Taylor G, Bennet AJ. Contribution of the active site aspartic acid to catalysis in the bacterial neuraminidase from Micromonospora viridifaciens. Febs Letters. 577: 265-9. PMID 15527797 DOI: 10.1016/J.Febslet.2004.10.016  0.326
2003 Watson JN, Dookhun V, Borgford TJ, Bennet AJ. Mutagenesis of the conserved active-site tyrosine changes a retaining sialidase into an inverting sialidase. Biochemistry. 42: 12682-90. PMID 14580216 DOI: 10.1021/Bi035396G  0.35
2000 Leblanc L, Bennet A, Borgford T. Calcium affinity of regulatory sites in skeletal troponin-C is attenuated by N-cap mutations of helix C. Archives of Biochemistry and Biophysics. 384: 296-304. PMID 11368316 DOI: 10.1006/Abbi.2000.2103  0.368
1998 Chou DT, Huang X, Batchelor RJ, Einstein FW, Bennet AJ. Rearrangement of a Homoallylic Alcohol via an Acid-Catalyzed 1,4-Hydride Shift Yields a Saturated Ketone. The Journal of Organic Chemistry. 63: 575-581. PMID 11672047 DOI: 10.1021/jo971465j  0.303
Show low-probability matches.