Sarah Ellen O'Connor - Related publications
Affiliations: | 2003-2011 | Chemistry | Massachusetts Institute of Technology, Cambridge, MA, United States |
| 2011- | Biological Chemistry | John Innes Center |
Area:
Biosynthesis and engineering of plant and plant-pathogen natural productsWebsite:
https://www.jic.ac.uk/people/professor-sarah-e-oconnor/
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50 most relevant papers in past 60 days:
50 most relevant papers in past 60 days:
| Year | Citation | Score | |
|---|---|---|---|
| 2021 | Li J, Xu F, Ji D, Tian C, Sun Y, Mutanda I, Ren Y, Wang Y. Diversion of metabolic flux towards 5-deoxy(iso)flavonoid production via enzyme self-assembly in . Metabolic Engineering Communications. 13: e00185. PMID 34631421 DOI: 10.1016/j.mec.2021.e00185 | ||
| 2021 | Vittorazzi PC, Marques JA, Takiya CS, Chesini RG, Bugoni M, da Silva GG, Nunes AT, Silva TBP, Dias MSS, Grigoletto NTS, Cortinhas CS, Acedo TS, Renno FP. Increasing doses of carbohydrases: Effects on rumen fermentation, nutrient digestibility, and performance of mid-lactation cows. Journal of Dairy Science. 104: 12508-12519. PMID 34600703 DOI: 10.3168/jds.2021-20514 | ||
| 2021 | Sharma V, Pugazhenthi G, Vasanth D. Production and characterization of a novel thermostable laccase from Bacillus licheniformis VNQ and its application in synthesis of bioactive 1,4-naphthoquinones. Journal of Bioscience and Bioengineering. PMID 34629297 DOI: 10.1016/j.jbiosc.2021.09.008 | ||
| 2021 | Li H, He YH, Hu YM, Chu QR, Chen YJ, Wu ZR, Zhang ZJ, Liu YQ, Yang CJ, Liang HJ, Yan YF. Design, Synthesis, and Structure-Activity Relationship Studies of Magnolol Derivatives as Antifungal Agents. Journal of Agricultural and Food Chemistry. PMID 34582205 DOI: 10.1021/acs.jafc.1c01838 | ||
| 2021 | Alafnan A, Sridharagatta S, Saleem H, Khurshid U, Alamri A, Ansari SY, Zainal Abidin SA, Ansari SA, Alamri AS, Ahemad N, Anwar S. Evaluation of the Phytochemical, Antioxidant, Enzyme Inhibition, and Wound Healing Potential of (L.) Dryand: A Source of a Bioactive Medicinal Product. Frontiers in Pharmacology. 12: 701369. PMID 34483902 DOI: 10.3389/fphar.2021.701369 | ||
| 2021 | Chen YJ, Ma KY, Du SS, Zhang ZJ, Wu TL, Sun Y, Liu YQ, Yin XD, Zhou R, Yan YF, Wang RX, He YH, Chu QR, Tang C. Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids. Journal of Agricultural and Food Chemistry. PMID 34623798 DOI: 10.1021/acs.jafc.1c05677 | ||
| 2021 | Liu Q, Liu Y, Li G, Savolainen O, Chen Y, Nielsen J. De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories. Nature Communications. 12: 6085. PMID 34667183 DOI: 10.1038/s41467-021-26361-1 | ||
| 2021 | Wei X, Matsuyama T, Sato H, Yan D, Chan PM, Miyamoto K, Uchiyama M, Matsuda Y. Molecular and Computational Bases for Spirofuranone Formation in Setosusin Biosynthesis. Journal of the American Chemical Society. PMID 34644070 DOI: 10.1021/jacs.1c08336 | ||
| 2021 | Keziah SM, Devi CS. Fibrinolytic and ACE Inhibitory Activity of Nattokinase Extracted from Bacillus subtilis VITMS 2: A Strain Isolated from Fermented Milk of Vigna unguiculata. The Protein Journal. 40: 876-890. PMID 34611797 DOI: 10.1007/s10930-021-10023-8 | ||
| 2021 | Chen Y, Wu J, Yu D, Du X. Advances in steroidal saponins biosynthesis. Planta. 254: 91. PMID 34617240 DOI: 10.1007/s00425-021-03732-y | ||
| 2021 | Wang S, Chen J, Shi J, Wang Z, Hu D, Song B. Novel Cinnamic Acid Derivatives Containing the 1,3,4-Oxadiazole Moiety: Design, Synthesis, Antibacterial Activities, and Mechanisms. Journal of Agricultural and Food Chemistry. PMID 34597041 DOI: 10.1021/acs.jafc.1c03087 | ||
| 2021 | Duhan M, Kumar P, Sindhu J, Singh R, Devi M, Kumar A, Kumar R, Lal S. Exploring biological efficacy of novel benzothiazole linked 2,5-disubstituted-1,3,4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization, inhibition, molecular docking, molecular dynamics and Monte Carlo based QSAR studies. Computers in Biology and Medicine. 138: 104876. PMID 34598068 DOI: 10.1016/j.compbiomed.2021.104876 | ||
| 2021 | Schultz F, Osuji OF, Wack B, Anywar G, Garbe LA. Antiinflammatory Medicinal Plants from the Ugandan Greater Mpigi Region Act as Potent Inhibitors in the COX-2/PGH Pathway. Plants (Basel, Switzerland). 10. PMID 33673238 DOI: 10.3390/plants10020351 | ||
| 2021 | Dey D, Dhar D, Fortunato H, Obata D, Tanaka A, Tanaka R, Basu S, Ito H. Insights into the structure and function of the rate-limiting enzyme of chlorophyll degradation through analysis of a bacterial Mg-dechelatase homolog. Computational and Structural Biotechnology Journal. 19: 5333-5347. PMID 34745453 DOI: 10.1016/j.csbj.2021.09.023 | ||
| 2021 | Marđetko N, Trontel A, Novak M, Pavlečić M, Ljubas BD, Grubišić M, Tominac VP, Ludwig R, Šantek B. Screening of Lignocellulolytic Enzyme Activities in Fungal Species and Sequential Solid-State and Submerged Cultivation for the Production of Enzyme Cocktails. Polymers. 13. PMID 34771293 DOI: 10.3390/polym13213736 | ||
| 2021 | Moore SJ, Tosi T, Bell D, Hleba YB, Polizzi KM, Freemont PS. High-yield 'one-pot' biosynthesis of raspberry ketone, a high-value fine chemical. Synthetic Biology (Oxford, England). 6: ysab021. PMID 34712844 DOI: 10.1093/synbio/ysab021 | ||
| 2021 | Zhang L, Feng XZ, Xiao ZQ, Fan GR, Chen SX, Liao SL, Luo H, Wang ZD. Design, Synthesis, Antibacterial, Antifungal and Anticancer Evaluations of Novel -Pinene Quaternary Ammonium Salts. International Journal of Molecular Sciences. 22. PMID 34681957 DOI: 10.3390/ijms222011299 | ||
| 2021 | Zhang JH, Xie HX, Li Y, Wang KM, Song Z, Zhu KK, Fang L, Zhang J, Jiang CS. Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 128413. PMID 34634473 DOI: 10.1016/j.bmcl.2021.128413 | ||
| 2021 | Zhang TJ, Tu S, Zhang X, Wang QY, Hu SS, Zhang Y, Zhang ZH, Wang ZR, Meng FH. Amide-based xanthine oxidase inhibitors bearing an N-(1-alkyl-3-cyano-1H-indol-5-yl) moiety: Design, synthesis and structure-activity relationship investigation. Bioorganic Chemistry. 117: 105417. PMID 34673452 DOI: 10.1016/j.bioorg.2021.105417 | ||
| 2021 | Bi H, Qu G, Wang S, Zhuang Y, Sun Z, Liu T, Ma Y. Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction. Metabolic Engineering. PMID 34715353 DOI: 10.1016/j.ymben.2021.10.010 | ||
| 2021 | Bisht R, Bhattacharyya A, Shrivastava A, Saxena P. An Overview of the Medicinally Important Plant Type III PKS Derived Polyketides. Frontiers in Plant Science. 12: 746908. PMID 34721474 DOI: 10.3389/fpls.2021.746908 | ||
| 2021 | Li Q, Ge L, Zheng D, Zhang X, Zhao L. Screening and characterization of a GH78 α-l-rhamnosidase from Aspergillus terreus and its application in the bioconversion of icariin to icaritin with recombinant β-glucosidase. Enzyme and Microbial Technology. 153: 109940. PMID 34781207 DOI: 10.1016/j.enzmictec.2021.109940 | ||
| 2021 | Yamamoto K, Grzech D, Koudounas K, Stander EA, Caputi L, Mimura T, Courdavault V, O'Connor SE. Improved virus-induced gene silencing allows discovery of a serpentine synthase gene in Catharanthus roseus. Plant Physiology. 187: 846-857. PMID 34608956 DOI: 10.1093/plphys/kiab285 | ||
| 2021 | Dissanayake AA, Mills GL, Bonito G, Rennick B, Nair MG. Chemical Composition and Anti-Inflammatory and Antioxidant Activities of Extracts from Cultivated Morel Mushrooms, Species of Genus Morchella (Ascomycota). International Journal of Medicinal Mushrooms. 23: 73-83. PMID 34591400 DOI: 10.1615/IntJMedMushrooms.2021039297 | ||
| 2021 | Linz AM, Ma Y, Perez JM, Myers KS, Kontur WS, Noguera DR, Donohue TJ. Aromatic dimer dehydrogenases from reduce monoaromatic diketones. Applied and Environmental Microbiology. AEM0174221. PMID 34613756 DOI: 10.1128/AEM.01742-21 | ||
| 2021 | Duong TH, Nguyen HT, Nguyen CH, Tran NM, Danova A, Tran TM, Vu-Huynh KL, Musa V, Jutakanoke R, Nguyen NH, Sichaem J. Identification of Highly Potent α-Glucosidase Inhibitors from Artocarpus integer and Molecular Docking Studies. Chemistry & Biodiversity. e2100499. PMID 34761862 DOI: 10.1002/cbdv.202100499 | ||
| 2021 | Kurze E, Ruß V, Syam N, Effenberger I, Jonczyk R, Liao J, Song C, Hoffmann T, Schwab W. Glucosylation of (±)-Menthol by Uridine-Diphosphate-Sugar Dependent Glucosyltransferases from Plants. Molecules (Basel, Switzerland). 26. PMID 34576983 DOI: 10.3390/molecules26185511 | ||
| 2021 | , Lambré C, Barat Baviera JM, Bolognesi C, Cocconcelli PS, Crebelli R, Gott DM, Grob K, Lampi E, Mengelers M, Mortensen A, Rivière G, Steffensen IL, Tlustos C, Van Loveren H, et al. Safety evaluation of the food enzyme d-psicose 3-epimerase from the genetically modified strain FIS002. Efsa Journal. European Food Safety Authority. 19: e06870. PMID 34703502 DOI: 10.2903/j.efsa.2021.6870 | ||
| 2021 | Wang J, Anderson K, Yang E, He L, Lidstrom ME. Enzyme engineering and testing of a formate reduction pathway. Synthetic Biology (Oxford, England). 6: ysab020. PMID 34651085 DOI: 10.1093/synbio/ysab020 | ||
| 2021 | Wang Y, Shi Y, Li K, Yang D, Liu N, Zhang L, Zhao L, Zhang X, Liu Y, Gao L, Xia T, Wang P. Roles of the 2-Oxoglutarate-Dependent Dioxygenase Superfamily in the Flavonoid Pathway: A Review of the Functional Diversity of F3H, FNS I, FLS, and LDOX/ANS. Molecules (Basel, Switzerland). 26. PMID 34771153 DOI: 10.3390/molecules26216745 | ||
| 2021 | Tran LT, Techato K, Nguyen VB, Wang SL, Nguyen AD, Phan TQ, Doan MD, Phoungthong K. Utilization of Cassava Wastewater for Low-Cost Production of Prodigiosin via TNU01 Fermentation and Its Novel Potent α-Glucosidase Inhibitory Effect. Molecules (Basel, Switzerland). 26. PMID 34684851 DOI: 10.3390/molecules26206270 | ||
| 2021 | Xu L, Chang KC, Payne EM, Modavi C, Liu L, Palmer CM, Tao N, Alper HS, Kennedy RT, Cornett DS, Abate AR. Mapping enzyme catalysis with metabolic biosensing. Nature Communications. 12: 6803. PMID 34815408 DOI: 10.1038/s41467-021-27185-9 | ||
| 2021 | Khobragade TP, Sarak S, Pagar AD, Jeon H, Giri P, Yun H. Synthesis of Sitagliptin Intermediate by a Multi-Enzymatic Cascade System Using Lipase and Transaminase With Benzylamine as an Amino Donor. Frontiers in Bioengineering and Biotechnology. 9: 757062. PMID 34692666 DOI: 10.3389/fbioe.2021.757062 | ||
| 2021 | Xu JJ, Chang YM, Lu M, Tie Y, Dong YL, Chen GY, Ma ZQ, Liu XL, Li YQ. Two single mutations in carboxylesterase 001C improve fenvalerate hydrolase activity in Helicoverpa armigera. Pesticide Biochemistry and Physiology. 179: 104969. PMID 34802519 DOI: 10.1016/j.pestbp.2021.104969 | ||
| 2021 | Pogorevc D, Müller R. Biotechnological production optimization of argyrins - a potent immunomodulatory natural product class. Microbial Biotechnology. PMID 34724343 DOI: 10.1111/1751-7915.13959 | ||
| 2021 | Zhang R, Tan S, Zhang B, Hu P, Li L. Cerium-Promoted Ginsenosides Accumulation by Regulating Endogenous Methyl Jasmonate Biosynthesis in Hairy Roots of . Molecules (Basel, Switzerland). 26. PMID 34577094 DOI: 10.3390/molecules26185623 | ||
| 2021 | Wang J, Su P, Gao L, Zhang Y, Wang J, Tu L, Zhao Y, Lu Y, Yin Y, Huang L, Gao W. A cytochrome P450 CYP81AM1 from Tripterygium wilfordii catalyses the C-15 hydroxylation of dehydroabietic acid. Planta. 254: 95. PMID 34643823 DOI: 10.1007/s00425-021-03743-9 | ||
| 2021 | Wang ZQ, Song H, Koleski EJ, Hara N, Park DS, Kumar G, Min Y, Dauenhauer PJ, Chang MCY. A dual cellular-heterogeneous catalyst strategy for the production of olefins from glucose. Nature Chemistry. PMID 34811478 DOI: 10.1038/s41557-021-00820-0 | ||
| 2021 | Jin LQ, Jin YT, Zhang JW, Liu ZQ, Zheng YG. Enhanced catalytic efficiency and thermostability of glucose isomerase from Thermoanaerobacter ethanolicus via site-directed mutagenesis. Enzyme and Microbial Technology. 152: 109931. PMID 34688091 DOI: 10.1016/j.enzmictec.2021.109931 | ||
| 2021 | Choub V, Ajuna HB, Won SJ, Moon JH, Choi SI, Maung CEH, Kim CW, Ahn YS. Antifungal Activity of CE 100 against Anthracnose Disease () and Growth Promotion of Walnut ( L.) Trees. International Journal of Molecular Sciences. 22. PMID 34638782 DOI: 10.3390/ijms221910438 | ||
| 2021 | Servi H, Goren N, Sen A, Servi EY. A new eudesmanolide from L. and biological activities of extracts. Natural Product Research. 1-11. PMID 34791965 DOI: 10.1080/14786419.2021.2005594 | ||
| 2021 | Ma QG, Tang Y, Sang ZP, Dong JH, Wei RR. Structurally diverse biflavonoids from the fruits of Citrus medica L. var. sarcodactylis Swingle and their hypolipidemic and immunosuppressive activities. Bioorganic Chemistry. 117: 105450. PMID 34710667 DOI: 10.1016/j.bioorg.2021.105450 | ||
| 2021 | Kitainda V, Jez JM. Structural Studies of Aliphatic Glucosinolate Chain-Elongation Enzymes. Antioxidants (Basel, Switzerland). 10. PMID 34573132 DOI: 10.3390/antiox10091500 | ||
| 2021 | Low YS, Garcia MD, Lonhienne T, Fraser JA, Schenk G, Guddat LW. Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads. Scientific Reports. 11: 21055. PMID 34702838 DOI: 10.1038/s41598-021-00349-9 | ||
| 2021 | Liao X, Teng L, Li W. Isolation and production of organic solvent tolerant protease from bacterial burn infection, Staphylococcus aureus KP091274. Cellular and Molecular Biology (Noisy-Le-Grand, France). 67: 142-147. PMID 34817325 DOI: 10.14715/cmb/2021.67.2.22 | ||
| 2021 | Zhang Y, Yang X, Luo ZX, Lai JL, Li C, Luo XG. Effects of polystyrene nanoplastics (PSNPs) on the physiology and molecular metabolism of corn (Zea mays L.) seedlings. The Science of the Total Environment. 150895. PMID 34655622 DOI: 10.1016/j.scitotenv.2021.150895 | ||
| 2021 | Xiao Z, Hou X, Zhang T, Yuan Y, Xiao J, Song W, Yue T. Starch-digesting product analysis based on the hydrophilic interaction liquid chromatography coupled mass spectrometry method to evaluate the inhibition of flavonoids on pancreatic α-amylase. Food Chemistry. 372: 131175. PMID 34653779 DOI: 10.1016/j.foodchem.2021.131175 | ||
| 2021 | Yu L, Zhou W, She Y, Ma H, Cai YS, Jiang M, Deng Z, Price NPJ, Chen W. Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system. Nature Communications. 12: 6633. PMID 34789759 DOI: 10.1038/s41467-021-26928-y | ||
| 2021 | Pan X, Yang J, Xie P, Zhang J, Ke F, Guo X, Liang M, Liu L, Wang Q, Gao X. Enhancement of Activity and Thermostability of Keratinase From CCTCC AB2013184 by Directed Evolution With Noncanonical Amino Acids. Frontiers in Bioengineering and Biotechnology. 9: 770907. PMID 34733836 DOI: 10.3389/fbioe.2021.770907 | ||
| 2021 | Mahour R, Lee JW, Grimpe P, Boecker S, Grote V, Klamt S, Seidel-Morgenstern A, Rexer TFT, Reichl U. Cell-free multi-enzyme synthesis and purification of uridine diphosphate galactose. Chembiochem : a European Journal of Chemical Biology. PMID 34637168 DOI: 10.1002/cbic.202100361 |