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Simon J Hedley - Publications

Affiliations: 
1995-2003 Chemistry University of Sheffield, Sheffield, England, United Kingdom 
 2003-2006 Chemistry State University of New York, Buffalo, Buffalo, NY, United States 
 2006-2018 Drug Substance Synthetic Technologies Amgen Inc., Thousand Oaks, CA, United States 
 2020-2021 Drug Substance Arcinova 
 2021- Drug Substance PR&D Quotient Sciences 
Area:
Process Chemistry, Organic Synthesis, Catalysis, Crystallisation, Biocatalysis
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, ... ... Hedley SJ, et al. Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors. Acs Medicinal Chemistry Letters. 6: 987-92. PMID 26396685 DOI: 10.1021/acsmedchemlett.5b00193  0.211
2007 Davies HM, Hedley SJ. Intermolecular reactions of electron-rich heterocycles with copper and rhodium carbenoids. Chemical Society Reviews. 36: 1109-19. PMID 17576478 DOI: 10.1039/B607983K  0.641
2007 Murthy V, Davies HM, Hedley SJ, Childers SR. Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain. Biochemical Pharmacology. 74: 336-44. PMID 17540345 DOI: 10.1016/J.Bcp.2007.04.019  0.422
2006 Hedley SJ, Ventura DL, Dominiak PM, Nygren CL, Davies HM. Investigation into factors influencing stereoselectivity in the reactions of heterocycles with donor-acceptor-substituted rhodium carbenoids. The Journal of Organic Chemistry. 71: 5349-56. PMID 16808525 DOI: 10.1021/Jo060779G  0.512
2005 Davies HM, Hedley SJ, Bohall BR. Asymmetric intermolecular C-H functionalization of benzyl silyl ethers mediated by chiral auxiliary-based aryldiazoacetates and chiral dirhodium catalysts. The Journal of Organic Chemistry. 70: 10737-42. PMID 16355994 DOI: 10.1021/Jo051747G  0.539
2003 Hedley SJ, Moran WJ, Price DA, Harrity JP. Development of a [3+3] cycloaddition strategy toward functionalized piperidines. The Journal of Organic Chemistry. 68: 4286-92. PMID 12762728 DOI: 10.1021/Jo030002C  0.625
2001 Hedley SJ, Moran WJ, Prenzel AGHP, Price DA, Harrity, JPA. Synthesis of Functionalised Piperidines Through a [3 + 3] Cycloaddition Strategy Synlett. 1596-1598. DOI: 10.1055/s-2001-17443  0.414
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