Qingtong Zhou - Publications

USTC, Downingtown, PA, United States 
drug screening, drug design, aptamer design, SELEX in silico

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhao F, Hang K, Zhou Q, Shao L, Li H, Li W, Lin S, Dai A, Cai X, Liu Y, Xu Y, Feng W, Yang D, Wang MW. Molecular basis of signal transduction mediated by the human GIPR splice variants. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306145120. PMID 37792509 DOI: 10.1073/pnas.2306145120  0.315
2023 Zhou Q, Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D, Vogt PK, Wang MW. Structural insights into the interaction of three Y-shaped ligands with PI3Kα. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304071120. PMID 37585458 DOI: 10.1073/pnas.2304071120  0.346
2022 Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, et al. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Research. PMID 35739238 DOI: 10.1038/s41422-022-00679-x  0.318
2021 Lin G, Feng Y, Cai X, Zhou C, Shao L, Chen Y, Chen L, Liu Q, Zhou Q, Bathgate RAD, Yang D, Wang MW. High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist. Molecules (Basel, Switzerland). 26. PMID 34946593 DOI: 10.3390/molecules26247511  0.301
2021 Wang X, Cheng X, Zhao L, Wang Y, Ye C, Zou X, Dai A, Cong Z, Chen J, Zhou Q, Xia T, Jiang H, Xu HE, Yang D, Wang MW. Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34353904 DOI: 10.1073/pnas.2101279118  0.326
2021 Zhou Q, Guo W, Dai A, Cai X, Vass M, de Graaf C, Shui W, Zhao S, Yang D, Wang MW. Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening. Biomolecules. 11. PMID 34201418 DOI: 10.3390/biom11070929  0.382
2021 Cong Z, Chen LN, Ma H, Zhou Q, Zou X, Ye C, Dai A, Liu Q, Huang W, Sun X, Wang X, Xu P, Zhao L, Xia T, Zhong W, et al. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nature Communications. 12: 3763. PMID 34145245 DOI: 10.1038/s41467-021-24058-z  0.345
2021 Lu Y, Liu H, Yang D, Zhong L, Xin Y, Zhao S, Wang MW, Zhou Q, Shui W. Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A Receptor Targeting the Sodium Ion Pocket. Acs Chemical Biology. PMID 34048655 DOI: 10.1021/acschembio.0c00899  0.386
2020 Lin G, Liu Q, Dai A, Cai X, Zhou Q, Wang X, Chen Y, Ye C, Li J, Yang D, Wang MW. Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders. The Biochemical Journal. 477: 2581-2594. PMID 32677665 DOI: 10.1042/Bcj20200235  0.306
2020 Wang YZ, Liu X, Way G, Madarha V, Zhou QT, Yang DH, Liao JY, Wang MW. An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9. Acta Pharmacologica Sinica. PMID 32341466 DOI: 10.1038/S41401-020-0405-7  0.32
2020 Tan L, Zhou Q, Yan W, Sun J, Kozikowski AP, Zhao S, Huang XP, Cheng J. Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands. Journal of Medicinal Chemistry. PMID 32282200 DOI: 10.1021/Acs.Jmedchem.9B01835  0.4
2019 Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu ZJ, Stevens RC, Lambert NA, Babu MM, Wang MW, et al. Common activation mechanism of class A GPCRs. Elife. 8. PMID 31855179 DOI: 10.7554/Elife.50279  0.561
2019 Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, et al. Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4. PMID 31801061 DOI: 10.1016/J.Celrep.2019.10.112  0.334
2019 Qu L, Zhou Q, Xu Y, Guo Y, Chen X, Yao D, Han GW, Liu ZJ, Stevens RC, Zhong G, Wu D, Zhao S. Structural Basis of the Diversity of Adrenergic Receptors. Cell Reports. 29: 2929-2935.e4. PMID 31801060 DOI: 10.1016/J.Celrep.2019.10.088  0.422
2019 Wu Y, Tong J, Ding K, Zhou Q, Zhao S. GPCR Allosteric Modulator Discovery. Advances in Experimental Medicine and Biology. 1163: 225-251. PMID 31707706 DOI: 10.1007/978-981-13-8719-7_10  0.401
2019 Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu Z, Stevens RC, Lambert NA, Babu MM, Wang M, et al. Author response: Common activation mechanism of class A GPCRs Elife. DOI: 10.7554/Elife.50279.Sa2  0.442
2018 Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/C7Sc04698G  0.441
2018 Qiu B, Xia B, Zhou Q, Lu Y, He M, Hasegawa K, Ma Z, Zhang F, Gu L, Mao Q, Wang F, Zhao S, Gao Z, Liao J. Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate. Cell Research. 28: 644-654. DOI: 10.2210/Pdb5Ys8/Pdb  0.312
2017 Ma Y, Yue Y, Ma Y, Zhang Q, Zhou Q, Song Y, Shen Y, Li X, Ma X, Li C, Hanson MA, Han GW, Sickmier EA, Swaminath G, Zhao S, et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure (London, England : 1993). PMID 28528775 DOI: 10.1016/J.Str.2017.04.008  0.428
2017 Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/Nature22378  0.376
2017 Zhou Q, Sun X, Xia X, Fan Z, Luo Z, Zhao S, Shakhnovich EI, Liang H. Exploring the Mutational Robustness of Nucleic Acids by Searching Genotype Neighbourhoods in Sequence Space. The Journal of Physical Chemistry Letters. PMID 28045264 DOI: 10.1021/Acs.Jpclett.6B02769  0.58
2016 Zhou Q, Liang H, Shakhnovich E. Virtual Screening of Human O-GlcNAc Transferase Inhibitors Chinese Journal of Chemical Physics. 29: 374-380. DOI: 10.1063/1674-0068/29/Cjcp1510211  0.562
2015 Zhou Q, Xia X, Luo Z, Liang H, Shakhnovich E. Searching the Sequence Space for Potent Aptamers Using SELEX in Silico. Journal of Chemical Theory and Computation. 11: 5939-46. PMID 26642994 DOI: 10.1021/Acs.Jctc.5B00707  0.596
2014 Li S, Chen D, Zhou Q, Wang W, Gao L, Jiang J, Liang H, Liu Y, Liang G, Cui H. A general chemiluminescence strategy for measuring aptamer-target binding and target concentration. Analytical Chemistry. 86: 5559-66. PMID 24828232 DOI: 10.1021/Ac501061C  0.56
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