| Year |
Citation |
Score |
| 2019 |
Okada H, Yagi R, Gardeux V, Deplancke B, Hafen E. Sex-dependent and sex-independent regulatory systems of size variation in natural populations. Molecular Systems Biology. 15: e9012. PMID 31777173 DOI: 10.15252/Msb.20199012 |
0.343 |
|
| 2016 |
Lujan E, Bornemann DJ, Rottig C, Bayless BA, Stocker H, Hafen E, Arora K, Warrior R. Analysis of novel alleles of brother of tout-velu, the Drosophila ortholog of human EXTL3 using a newly developed FRT42D ovo(D) chromosome. Genesis (New York, N.Y. : 2000). PMID 27636555 DOI: 10.1002/Dvg.22981 |
0.337 |
|
| 2016 |
Okada H, Ebhardt HA, Vonesch SC, Aebersold R, Hafen E. Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. Nature Communications. 7: 12649. PMID 27582081 DOI: 10.1038/Ncomms12649 |
0.303 |
|
| 2016 |
Vonesch SC, Lamparter D, Mackay TF, Bergmann S, Hafen E. Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. Plos Genetics. 12: e1005616. PMID 26751788 DOI: 10.1371/Journal.Pgen.1005616 |
0.372 |
|
| 2015 |
Okada H, Schittenhelm RB, Straessle A, Hafen E. Multi-functional regulation of 4E-BP gene expression by the Ccr4-Not complex. Plos One. 10: e0113902. PMID 25793896 DOI: 10.1371/Journal.Pone.0113902 |
0.389 |
|
| 2014 |
Handke B, Szabad J, Lidsky PV, Hafen E, Lehner CF. Towards long term cultivation of Drosophila wing imaginal discs in vitro. Plos One. 9: e107333. PMID 25203426 DOI: 10.1371/Journal.Pone.0107333 |
0.331 |
|
| 2013 |
Baumgartner R, Stocker H, Hafen E. The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster. Plos Genetics. 9: e1003598. PMID 23874212 DOI: 10.1371/Journal.Pgen.1003598 |
0.408 |
|
| 2013 |
Nowak K, Seisenbacher G, Hafen E, Stocker H. Nutrient restriction enhances the proliferative potential of cells lacking the tumor suppressor PTEN in mitotic tissues. Elife. 2: e00380. PMID 23853709 DOI: 10.7554/Elife.00380 |
0.375 |
|
| 2013 |
Sarraf-Zadeh L, Christen S, Sauer U, Cognigni P, Miguel-Aliaga I, Stocker H, Köhler K, Hafen E. Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions. Developmental Biology. 381: 97-106. PMID 23773803 DOI: 10.1016/J.Ydbio.2013.06.008 |
0.311 |
|
| 2013 |
Almudi I, Poernbacher I, Hafen E, Stocker H. The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction. Cell Communication and Signaling : Ccs. 11: 26. PMID 23590848 DOI: 10.1186/1478-811X-11-26 |
0.309 |
|
| 2013 |
Guan XL, Cestra G, Shui G, Kuhrs A, Schittenhelm RB, Hafen E, van der Goot FG, Robinett CC, Gatti M, Gonzalez-Gaitan M, Wenk MR. Biochemical membrane lipidomics during Drosophila development. Developmental Cell. 24: 98-111. PMID 23260625 DOI: 10.1016/J.Devcel.2012.11.012 |
0.307 |
|
| 2012 |
Barth JM, Hafen E, Köhler K. The lack of autophagy triggers precocious activation of Notch signaling during Drosophila oogenesis. Bmc Developmental Biology. 12: 35. PMID 23217079 DOI: 10.1186/1471-213X-12-35 |
0.379 |
|
| 2011 |
Glatter T, Schittenhelm RB, Rinner O, Roguska K, Wepf A, Jünger MA, Köhler K, Jevtov I, Choi H, Schmidt A, Nesvizhskii AI, Stocker H, Hafen E, Aebersold R, Gstaiger M. Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome. Molecular Systems Biology. 7: 547. PMID 22068330 DOI: 10.1038/Msb.2011.79 |
0.403 |
|
| 2011 |
Seisenbacher G, Hafen E, Stocker H. MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress. Plos Genetics. 7: e1002168. PMID 21829386 DOI: 10.1371/Journal.Pgen.1002168 |
0.332 |
|
| 2011 |
Kim Y, Paroush Z, Nairz K, Hafen E, Jiménez G, Shvartsman SY. Substrate-dependent control of MAPK phosphorylation in vivo. Molecular Systems Biology. 7: 467. PMID 21283143 DOI: 10.1038/Msb.2010.121 |
0.329 |
|
| 2011 |
Barth JM, Szabad J, Hafen E, Köhler K. Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis. Cell Death and Differentiation. 18: 915-24. PMID 21151027 DOI: 10.1038/Cdd.2010.157 |
0.393 |
|
| 2010 |
Montagne J, Lecerf C, Parvy JP, Bennion JM, Radimerski T, Ruhf ML, Zilbermann F, Vouilloz N, Stocker H, Hafen E, Kozma SC, Thomas G. The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in Drosophila. Plos Genetics. 6: e1000937. PMID 20463884 DOI: 10.1371/Journal.Pgen.1000937 |
0.432 |
|
| 2010 |
Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/Journal.Pgen.1000881 |
0.412 |
|
| 2010 |
Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H. The WW domain protein Kibra acts upstream of Hippo in Drosophila. Developmental Cell. 18: 309-16. PMID 20159600 DOI: 10.1016/J.Devcel.2009.12.013 |
0.401 |
|
| 2010 |
Aegerter-Wilmsen T, Smith AC, Christen AJ, Aegerter CM, Hafen E, Basler K. Exploring the effects of mechanical feedback on epithelial topology. Development (Cambridge, England). 137: 499-506. PMID 20081194 DOI: 10.1242/Dev.041731 |
0.578 |
|
| 2009 |
Goetze S, Qeli E, Mosimann C, Staes A, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, et al. Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. Plos Biology. 7: e1000236. PMID 19885390 DOI: 10.1371/Journal.Pbio.1000236 |
0.548 |
|
| 2009 |
Werz C, Köhler K, Hafen E, Stocker H. The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. Plos Genetics. 5: e1000596. PMID 19680438 DOI: 10.1371/Journal.Pgen.1000596 |
0.399 |
|
| 2009 |
Köhler K, Brunner E, Guan XL, Boucke K, Greber UF, Mohanty S, Barth JM, Wenk MR, Hafen E. A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy. 5: 980-90. PMID 19587536 DOI: 10.4161/Auto.5.7.9325 |
0.368 |
|
| 2009 |
Hafen E. Pushing single-gene genetic analysis up a Notch. Developmental Cell. 16: 623-4. PMID 19460336 DOI: 10.1016/J.Devcel.2009.05.006 |
0.316 |
|
| 2009 |
Almudi I, Stocker H, Hafen E, Corominas M, Serras F. SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development. Developmental Biology. 326: 212-23. PMID 19083999 DOI: 10.1016/J.Ydbio.2008.11.014 |
0.481 |
|
| 2008 |
Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. Plos One. 3: e3721. PMID 19005568 DOI: 10.1371/Journal.Pone.0003721 |
0.349 |
|
| 2008 |
Honegger B, Galic M, Köhler K, Wittwer F, Brogiolo W, Hafen E, Stocker H. Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. Journal of Biology. 7: 10. PMID 18412985 DOI: 10.1186/Jbiol72 |
0.305 |
|
| 2008 |
Wu X, Yamada-Mabuchi M, Morris EJ, Tanwar PS, Dobens L, Gluderer S, Khan S, Cao J, Stocker H, Hafen E, Dyson NJ, Raftery LA. The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival. Proceedings of the National Academy of Sciences of the United States of America. 105: 5414-9. PMID 18375761 DOI: 10.1073/Pnas.0800945105 |
0.417 |
|
| 2008 |
Gluderer S, Oldham S, Rintelen F, Sulzer A, Schütt C, Wu X, Raftery LA, Hafen E, Stocker H. Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth. Bmc Developmental Biology. 8: 10. PMID 18226226 DOI: 10.1186/1471-213X-8-10 |
0.319 |
|
| 2008 |
Wang Y, Werz C, Xu D, Chen Z, Li Y, Hafen E, Bergmann A. Drosophila cbl is essential for control of cell death and cell differentiation during eye development. Plos One. 3: e1447. PMID 18197257 DOI: 10.1371/Journal.Pone.0001447 |
0.408 |
|
| 2007 |
Ahrens CH, Brunner E, Hafen E, Aebersold R, Basler K. A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly. 1: 182-6. PMID 18820430 DOI: 10.4161/Fly.4532 |
0.537 |
|
| 2007 |
Aegerter-Wilmsen T, Aegerter CM, Hafen E, Basler K. Model for the regulation of size in the wing imaginal disc of Drosophila. Mechanisms of Development. 124: 318-26. PMID 17293093 DOI: 10.1016/J.Mod.2006.12.005 |
0.529 |
|
| 2006 |
Sesé M, Corominas M, Stocker H, Heino TI, Hafen E, Serras F. The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye. Journal of Cell Science. 119: 5047-56. PMID 17118962 DOI: 10.1242/Jcs.03294 |
0.463 |
|
| 2006 |
O'Reilly AM, Ballew AC, Miyazawa B, Stocker H, Hafen E, Simon MA. Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells. Development (Cambridge, England). 133: 2627-38. PMID 16775001 DOI: 10.1242/Dev.02423 |
0.565 |
|
| 2005 |
Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R. A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Molecular & Cellular Proteomics : McP. 4: 1725-40. PMID 16085932 DOI: 10.1074/Mcp.M500231-Mcp200 |
0.303 |
|
| 2005 |
Wittwer F, Jaquenoud M, Brogiolo W, Zarske M, Wüstemann P, Fernandez R, Stocker H, Wymann MP, Hafen E. Susi, a negative regulator of Drosophila PI3-kinase. Developmental Cell. 8: 817-27. PMID 15935772 DOI: 10.1016/J.Devcel.2005.04.002 |
0.399 |
|
| 2005 |
Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, Driege Y, Martinez P, Hafen E, Withers DJ, Leevers SJ, Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proceedings of the National Academy of Sciences of the United States of America. 102: 3105-10. PMID 15708981 DOI: 10.1073/Pnas.0405775102 |
0.312 |
|
| 2005 |
Zipperlen P, Nairz K, Rimann I, Basler K, Hafen E, Hengartner M, Hajnal A. A universal method for automated gene mapping. Genome Biology. 6: R19. PMID 15693948 DOI: 10.1186/Gb-2005-6-2-R19 |
0.533 |
|
| 2005 |
Frei C, Galloni M, Hafen E, Edgar BA. The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth. The Embo Journal. 24: 623-34. PMID 15692573 DOI: 10.1038/Sj.Emboj.7600523 |
0.396 |
|
| 2005 |
Reiling JH, Doepfner KT, Hafen E, Stocker H. Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E. Current Biology : Cb. 15: 24-30. PMID 15649360 DOI: 10.1016/J.Cub.2004.12.034 |
0.368 |
|
| 2004 |
Reiling JH, Hafen E. The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes & Development. 18: 2879-92. PMID 15545626 DOI: 10.1101/Gad.322704 |
0.37 |
|
| 2004 |
Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG. Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes & Development. 18: 2893-904. PMID 15545625 DOI: 10.1101/Gad.1256804 |
0.344 |
|
| 2004 |
Nairz K, Zipperlen P, Dearolf C, Basler K, Hafen E. A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biology. 5: R83. PMID 15461801 DOI: 10.1186/Gb-2004-5-10-R83 |
0.547 |
|
| 2004 |
Ryder E, Blows F, Ashburner M, Bautista-Llacer R, Coulson D, Drummond J, Webster J, Gubb D, Gunton N, Johnson G, O'Kane CJ, Huen D, Sharma P, Asztalos Z, Baisch H, ... ... Hafen E, et al. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics. 167: 797-813. PMID 15238529 DOI: 10.1534/Genetics.104.026658 |
0.692 |
|
| 2004 |
MacDougall LK, Gagou ME, Leevers SJ, Hafen E, Waterfield MD. Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways. Molecular and Cellular Biology. 24: 796-808. PMID 14701751 DOI: 10.1128/Mcb.24.2.796-808.2004 |
0.386 |
|
| 2004 |
Leevers SJ, Hafen E. 6 Growth Regulation by Insulin and TOR Signaling in Drosophila Cold Spring Harbor Monograph Archive. 42: 167-192. DOI: 10.1101/087969672.42.167 |
0.36 |
|
| 2003 |
Hafen E, Stocker H. How are the sizes of cells, organs, and bodies controlled? Plos Biology. 1: E86. PMID 14691557 DOI: 10.1371/Journal.Pbio.0000086 |
0.32 |
|
| 2003 |
Jünger MA, Rintelen F, Stocker H, Wasserman JD, Végh M, Radimerski T, Greenberg ME, Hafen E. The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. Journal of Biology. 2: 20. PMID 12908874 DOI: 10.1186/1475-4924-2-20 |
0.388 |
|
| 2003 |
Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, Stocker H, Kozma SC, Hafen E, Bos JL, Thomas G. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Molecular Cell. 11: 1457-66. PMID 12820960 DOI: 10.1016/S1097-2765(03)00220-X |
0.38 |
|
| 2003 |
Rintelen F, Hafen E, Nairz K. The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER. Development (Cambridge, England). 130: 3479-90. PMID 12810595 DOI: 10.1242/Dev.00568 |
0.459 |
|
| 2003 |
Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, Daram P, Breuer S, Thomas G, Hafen E. Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nature Cell Biology. 5: 559-65. PMID 12766775 DOI: 10.1038/Ncb995 |
0.397 |
|
| 2003 |
Egli D, Selvaraj A, Yepiskoposyan H, Zhang B, Hafen E, Georgiev O, Schaffner W. Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. The Embo Journal. 22: 100-8. PMID 12505988 DOI: 10.1093/Emboj/Cdg012 |
0.33 |
|
| 2002 |
Ikeya T, Galic M, Belawat P, Nairz K, Hafen E. Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Current Biology : Cb. 12: 1293-300. PMID 12176357 DOI: 10.1016/S0960-9822(02)01043-6 |
0.373 |
|
| 2002 |
Oldham S, Stocker H, Laffargue M, Wittwer F, Wymann M, Hafen E. The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development (Cambridge, England). 129: 4103-9. PMID 12163412 DOI: 10.5167/Uzh-623 |
0.373 |
|
| 2002 |
Bellotto M, Bopp D, Senti KA, Burke R, Deak P, Maroy P, Dickson B, Basler K, Hafen E. Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. The International Journal of Developmental Biology. 46: 149-57. PMID 11902676 DOI: 10.1387/Ijdb.11902676 |
0.66 |
|
| 2002 |
Stocker H, Andjelkovic M, Oldham S, Laffargue M, Wymann MP, Hemmings BA, Hafen E. Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB. Science (New York, N.Y.). 295: 2088-91. PMID 11872800 DOI: 10.1126/Science.1068094 |
0.355 |
|
| 2002 |
Radimerski T, Montagne J, Rintelen F, Stocker H, van der Kaay J, Downes CP, Hafen E, Thomas G. dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nature Cell Biology. 4: 251-5. PMID 11862217 DOI: 10.1038/Ncb763 |
0.389 |
|
| 2001 |
Morey M, Serras F, Baguñà J, Hafen E, Corominas M. Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Developmental Biology. 238: 145-56. PMID 11784000 DOI: 10.1006/Dbio.2001.0389 |
0.391 |
|
| 2001 |
Rintelen F, Stocker H, Thomas G, Hafen E. PDK1 regulates growth through Akt and S6K in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 98: 15020-5. PMID 11752451 DOI: 10.1073/Pnas.011318098 |
0.393 |
|
| 2001 |
Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science (New York, N.Y.). 292: 104-6. PMID 11292874 DOI: 10.1126/Science.1057991 |
0.321 |
|
| 2001 |
Halfar K, Rommel C, Stocker H, Hafen E. Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development (Cambridge, England). 128: 1687-96. PMID 11290305 DOI: 10.5167/Uzh-625 |
0.387 |
|
| 2001 |
Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, Hafen E. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Current Biology : Cb. 11: 213-21. PMID 11250149 DOI: 10.1016/S0960-9822(01)00068-9 |
0.384 |
|
| 2001 |
Wittwer F, van der Straten A, Keleman K, Dickson BJ, Hafen E. Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development (Cambridge, England). 128: 791-800. PMID 11171403 DOI: 10.5167/Uzh-651 |
0.761 |
|
| 2000 |
Oldham S, Böhni R, Stocker H, Brogiolo W, Hafen E. Genetic control of size in Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 945-52. PMID 11128988 DOI: 10.1098/Rstb.2000.0630 |
0.368 |
|
| 2000 |
Oldham S, Montagne J, Radimerski T, Thomas G, Hafen E. Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes & Development. 14: 2689-94. PMID 11069885 DOI: 10.1101/Gad.845700 |
0.369 |
|
| 2000 |
Stocker H, Hafen E. Genetic control of cell size. Current Opinion in Genetics & Development. 10: 529-35. PMID 10980431 DOI: 10.1016/S0959-437X(00)00123-4 |
0.379 |
|
| 2000 |
Jenni M, Basler K, Hafen E, Aguet M. A newly founded Swiss biotech company Chimia. 54: 236-238. |
0.421 |
|
| 1999 |
Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell. 99: 803-15. PMID 10619433 DOI: 10.1016/S0092-8674(00)81677-3 |
0.665 |
|
| 1999 |
Huang H, Potter CJ, Tao W, Li DM, Brogiolo W, Hafen E, Sun H, Xu T. PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development (Cambridge, England). 126: 5365-72. PMID 10556061 |
0.327 |
|
| 1999 |
Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, Thomas G. Drosophila S6 kinase: a regulator of cell size. Science (New York, N.Y.). 285: 2126-9. PMID 10497130 DOI: 10.1126/Science.285.5436.2126 |
0.414 |
|
| 1999 |
Böhni R, Riesgo-Escovar J, Oldham S, Brogiolo W, Stocker H, Andruss BF, Beckingham K, Hafen E. Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell. 97: 865-75. PMID 10399915 DOI: 10.1016/S0092-8674(00)80799-0 |
0.41 |
|
| 1999 |
Feldmann P, Eicher EN, Leevers SJ, Hafen E, Hughes DA. Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein. Molecular and Cellular Biology. 19: 1928-37. PMID 10022880 DOI: 10.1128/Mcb.19.3.1928 |
0.385 |
|
| 1999 |
Brunner E, Brunner D, Fu W, Hafen E, Basler K. The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Developmental Biology. 206: 178-88. PMID 9986731 DOI: 10.1006/Dbio.1998.9136 |
0.589 |
|
| 1998 |
Eberle KK, Zinsmaier KE, Buchner S, Gruhn M, Jenni M, Arnold C, Leibold C, Reisch D, Walter N, Hafen E, Hofbauer A, Pflugfelder GO, Buchner E. Wide distribution of the cysteine string proteins in Drosophila tissues revealed by targeted mutagenesis. Cell and Tissue Research. 294: 203-17. PMID 9799436 DOI: 10.1007/S004410051170 |
0.344 |
|
| 1998 |
Rommel C, Hafen E. Ras--a versatile cellular switch. Current Opinion in Genetics & Development. 8: 412-8. PMID 9729716 DOI: 10.1016/S0959-437X(98)80111-1 |
0.322 |
|
| 1998 |
Hafen E. Kinases and phosphatases--a marriage is consummated. Science (New York, N.Y.). 280: 1212-3. PMID 9634402 DOI: 10.1126/Science.280.5367.1212 |
0.334 |
|
| 1997 |
Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4 |
0.529 |
|
| 1997 |
DomÃnguez M, Hafen E. Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye. Genes & Development. 11: 3254-64. PMID 9389656 DOI: 10.1101/Gad.11.23.3254 |
0.372 |
|
| 1997 |
Riesgo-Escovar JR, Hafen E. Common and distinct roles of DFos and DJun during Drosophila development. Science (New York, N.Y.). 278: 669-72. PMID 9381174 DOI: 10.1126/Science.278.5338.669 |
0.418 |
|
| 1997 |
Rommel C, Radziwill G, Moelling K, Hafen E. Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo. Mechanisms of Development. 64: 95-104. PMID 9232600 DOI: 10.1016/S0925-4773(97)00052-X |
0.353 |
|
| 1997 |
Riesgo-Escovar JR, Hafen E. Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes & Development. 11: 1717-27. PMID 9224720 DOI: 10.1101/Gad.11.13.1717 |
0.45 |
|
| 1997 |
van der Straten A, Rommel C, Dickson B, Hafen E. The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila. The Embo Journal. 16: 1961-9. PMID 9155022 DOI: 10.1093/Emboj/16.8.1961 |
0.554 |
|
| 1996 |
Leevers SJ, Weinkove D, MacDougall LK, Hafen E, Waterfield MD. The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. The Embo Journal. 15: 6584-94. PMID 8978685 |
0.339 |
|
| 1996 |
Riesgo-Escovar JR, Jenni M, Fritz A, Hafen E. The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes & Development. 10: 2759-68. PMID 8946916 DOI: 10.1101/Gad.10.21.2759 |
0.44 |
|
| 1996 |
Oellers N, Hafen E. Biochemical characterization of rolledSem, an activated form of Drosophila mitogen-activated protein kinase. The Journal of Biological Chemistry. 271: 24939-44. PMID 8798773 DOI: 10.1074/Jbc.271.40.24939 |
0.386 |
|
| 1996 |
Dickson BJ, van der Straten A, Dominguez M, Hafen E. Mutations Modulating Raf signaling in Drosophila eye development. Genetics. 142: 163-71. PMID 8770593 DOI: 10.5167/Uzh-656 |
0.603 |
|
| 1996 |
Raabe T, Riesgo-Escovar J, Liu X, Bausenwein BS, Deak P, Maröy P, Hafen E. DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila. Cell. 85: 911-20. PMID 8681385 DOI: 10.1016/S0092-8674(00)81274-X |
0.455 |
|
| 1996 |
DomÃnguez M, Brunner M, Hafen E, Basler K. Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science (New York, N.Y.). 272: 1621-5. PMID 8658135 DOI: 10.1126/Science.272.5268.1621 |
0.601 |
|
| 1996 |
Guillemin K, Groppe J, Ducker K, Treisman R, Hafen E, Affolter M, Krasnow MA. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development (Cambridge, England). 122: 1353-62. PMID 8625824 DOI: 10.5167/Uzh-664 |
0.595 |
|
| 1996 |
Domínguez M, Hafen E. Genetic dissection of cell fate specification in the developing eye of Drosophila Seminars in Cell and Developmental Biology. 7: 219-226. DOI: 10.1006/Scdb.1996.0029 |
0.461 |
|
| 1995 |
Dickson BJ, DomÃnguez M, van der Straten A, Hafen E. Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase. Cell. 80: 453-62. PMID 7859287 DOI: 10.1016/0092-8674(95)90496-4 |
0.615 |
|
| 1995 |
Raabe T, Olivier JP, Dickson B, Liu X, Gish GD, Pawson T, Hafen E. Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila. The Embo Journal. 14: 2509-18. PMID 7781603 DOI: 10.1002/J.1460-2075.1995.Tb07248.X |
0.553 |
|
| 1994 |
Dickson B, Hafen E. Genetics of signal transduction in invertebrates. Current Opinion in Genetics & Development. 4: 64-70. PMID 8193542 DOI: 10.1016/0959-437X(94)90092-2 |
0.583 |
|
| 1994 |
Biggs WH, Zavitz KH, Dickson B, van der Straten A, Brunner D, Hafen E, Zipursky SL. The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. The Embo Journal. 13: 1628-35. PMID 8157002 DOI: 10.1002/J.1460-2075.1994.Tb06426.X |
0.542 |
|
| 1994 |
Reichman-Fried M, Dickson B, Hafen E, Shilo BZ. Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes & Development. 8: 428-39. PMID 8125257 DOI: 10.1101/Gad.8.4.428 |
0.602 |
|
| 1994 |
Brunner D, Oellers N, Szabad J, Biggs WH, Zipursky SL, Hafen E. A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell. 76: 875-88. PMID 8124723 DOI: 10.1016/0092-8674(94)90362-X |
0.412 |
|
| 1994 |
Hafen E, Dickson B, Brunner D, Raabe T. Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila. Progress in Neurobiology. 42: 287-92. PMID 8008827 DOI: 10.1016/0301-0082(94)90067-1 |
0.622 |
|
| 1993 |
Hafen E, Dickson B, Raabe T, Brunner D, Oellers N, van der Straten A. Genetic analysis of the sevenless signal transduction pathway of Drosophila. Development (Cambridge, England). 119: 41-6. PMID 27002030 |
0.579 |
|
| 1993 |
Olivier JP, Raabe T, Henkemeyer M, Dickson B, Mbamalu G, Margolis B, Schlessinger J, Hafen E, Pawson T. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell. 73: 179-91. PMID 8462098 DOI: 10.1016/0092-8674(93)90170-U |
0.554 |
|
| 1993 |
Hafen E, Dickson B, Brunner T, Raabe T. Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 340: 273-8. PMID 8103929 DOI: 10.1098/Rstb.1993.0068 |
0.622 |
|
| 1993 |
Hafen E, Dickson B, Raabe T, Brunner D, Oellers N, van der Straten A. Genetic analysis of the sevenless signal transduction pathway of Drosophila. Development (Cambridge, England). Supplement. 41-6. PMID 8049486 |
0.579 |
|
| 1992 |
Dickson B, Sprenger F, Morrison D, Hafen E. Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature. 360: 600-3. PMID 1461284 DOI: 10.1038/360600A0 |
0.624 |
|
| 1992 |
Dambly-Chaudière C, Jamet E, Burri M, Bopp D, Basler K, Hafen E, Dumont N, Spielmann P, Ghysen A, Noll M. The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell. 69: 159-72. PMID 1348214 DOI: 10.1016/0092-8674(92)90127-X |
0.577 |
|
| 1992 |
Dickson B, Sprenger F, Hafen E. Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor. Genes & Development. 6: 2327-39. PMID 1334023 DOI: 10.1101/Gad.6.12A.2327 |
0.607 |
|
| 1991 |
Basler K, Christen B, Hafen E. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell. 64: 1069-81. PMID 2004416 DOI: 10.1016/0092-8674(91)90262-W |
0.653 |
|
| 1991 |
Hafen E. Patterning by cell recruitment in the Drosophila eye. Current Opinion in Genetics & Development. 1: 268-74. PMID 1822274 DOI: 10.1016/S0959-437X(05)80081-4 |
0.345 |
|
| 1991 |
Basler K, Hafen E. Specification of cell fate in the developing eye of Drosophila. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 621-31. PMID 1789779 DOI: 10.1002/Bies.950131202 |
0.661 |
|
| 1991 |
Hafen E, Basler K. Specification of cell fate in the developing eye of Drosophila. Development (Cambridge, England). Supplement. 1: 123-30. PMID 1742497 |
0.62 |
|
| 1990 |
Hafen E, Basler K. Role of receptor tyrosine kinases during Drosophila development. Ciba Foundation Symposium. 150: 191-204; discussion . PMID 2164907 |
0.641 |
|
| 1990 |
Hafen E, Basler K. Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough. Journal of Cell Science. Supplement. 13: 157-68. PMID 1982113 DOI: 10.1242/Jcs.1990.Supplement_13.15 |
0.646 |
|
| 1990 |
Basler K, Yen D, Tomlinson A, Hafen E. Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough. Genes & Development. 4: 728-39. PMID 1974229 DOI: 10.1101/Gad.4.5.728 |
0.68 |
|
| 1990 |
Basler K, Hafen E. Receptor tyrosine kinases mediate cell-cell interactions during Drosophila development. Progress in Growth Factor Research. 2: 15-27. PMID 1966557 DOI: 10.1016/0955-2235(90)90007-7 |
0.682 |
|
| 1989 |
Basler K, Siegrist P, Hafen E. The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements. The Embo Journal. 8: 2381-6. PMID 2792089 DOI: 10.1002/J.1460-2075.1989.Tb08367.X |
0.607 |
|
| 1989 |
Basler K, Hafen E. Dynamics of Drosophila eye development and temporal requirements of sevenless expression. Development (Cambridge, England). 107: 723-31. PMID 2632232 |
0.573 |
|
| 1989 |
Basler K, Hafen E. Ubiquitous expression of sevenless: position-dependent specification of cell fate. Science (New York, N.Y.). 243: 931-4. PMID 2493159 DOI: 10.1126/Science.2493159 |
0.612 |
|
| 1988 |
Basler K, Hafen E. Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate. Trends in Genetics : Tig. 4: 74-9. PMID 3076295 DOI: 10.1016/0168-9525(88)90044-3 |
0.652 |
|
| 1988 |
Basler K, Hafen E. Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain. Cell. 54: 299-311. PMID 2840202 |
0.575 |
|
| 1987 |
Tomlinson A, Bowtell DD, Hafen E, Rubin GM. Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila. Cell. 51: 143-50. PMID 3115593 DOI: 10.1016/0092-8674(87)90019-5 |
0.735 |
|
| 1987 |
Hafen E, Basler K, Edstroem JE, Rubin GM. Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science (New York, N.Y.). 236: 55-63. PMID 2882603 DOI: 10.1126/Science.2882603 |
0.725 |
|
| 1985 |
Montell C, Jones K, Hafen E, Rubin G. Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science (New York, N.Y.). 230: 1040-3. PMID 3933112 DOI: 10.1126/Science.3933112 |
0.715 |
|
| 1984 |
Hafen E, Kuroiwa A, Gehring WJ. Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development. Cell. 37: 833-41. PMID 6430568 DOI: 10.1016/0092-8674(84)90418-5 |
0.494 |
|
| 1984 |
Kuroiwa A, Hafen E, Gehring WJ. Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell. 37: 825-31. PMID 6430567 DOI: 10.1016/0092-8674(84)90417-3 |
0.478 |
|
| 1984 |
Hafen E, Levine M, Gehring WJ. Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila. Nature. 307: 287-9. PMID 6420705 DOI: 10.1038/307287a0 |
0.607 |
|
| 1984 |
McGinnis W, Levine MS, Hafen E, Kuroiwa A, Gehring WJ. A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature. 308: 428-33. PMID 6323992 DOI: 10.1038/308428A0 |
0.7 |
|
| 1983 |
Hafen E, Levine M, Garber RL, Gehring WJ. An improved in situ hybridization method for the detection of cellular RNAs in Drosophila tissue sections and its application for localizing transcripts of the homeotic Antennapedia gene complex. The Embo Journal. 2: 617-23. PMID 16453446 |
0.703 |
|
| 1983 |
Levine M, Hafen E, Garber RL, Gehring WJ. Spatial distribution of Antennapedia transcripts during Drosophila development. The Embo Journal. 2: 2037-46. PMID 6416828 |
0.703 |
|
| 1983 |
Hafen E, Levine M, Garber RL, Gehring WJ. An improved in situ hybridization method for the detection of cellular RNAs in Drosophila tissue sections and its application for localizing transcripts of the homeotic Antennapedia gene complex. The Embo Journal. 2: 617-623. DOI: 10.1002/J.1460-2075.1983.Tb01472.X |
0.489 |
|
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