☰

Feng Zhang - Publications

Affiliations: 
Fudan university, Shanghai, Shanghai Shi, China 
Area:
Human Genetics
Website:
http://www.gdg-fudan.org/?page_id=382
Tree Info Grants Similar researchers PubMed Report error

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gao L, Zhang F, Hejtmancik JF, Jiao X, Jia L, Peng X, Ma K, Li Q. Phenotypic and Genotypic Features of a Chinese Cohort with Retinal Hemangioblastoma. Genes. 15. PMID 39336783 DOI: 10.3390/genes15091192  0.312
2024 Tian S, Faheem M, Satti HS, Xiao J, Zhang F, Khan TN, Liu C. A homozygous missense variant in YTHDC2 induces azoospermia in two siblings. Molecular Genetics and Genomics : Mgg. 299: 84. PMID 39223386 DOI: 10.1007/s00438-024-02168-9  0.389
2024 Zhou D, Wu H, Wang L, Wang X, Tang S, Zhou Y, Wang J, Wu B, Tang J, Zhou X, Tian S, Liu S, Lv M, He X, Jin L, ... ... Zhang F, et al. Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 38909778 DOI: 10.1016/j.jgg.2024.06.008  0.368
2024 Song C, Qin Y, Li Y, Yang B, Guo T, Ma W, Xu D, Xu K, Fu F, Jin L, Wu Y, Tang S, Chen X, Zhang F. Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice. Science China. Life Sciences. PMID 38874713 DOI: 10.1007/s11427-024-2606-6  0.423
2024 Mori T, Fujimaru T, Liu C, Patterson K, Yamamoto K, Suzuki T, Chiga M, Sekine A, Ubara Y, Miller DE, Galey M, Mandai S, Ando F, Mori Y, Kikuchi H, ... ... Zhang F, et al. CFAP47 is a novel causative gene implicated in X-linked polycystic kidney disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38633811 DOI: 10.1101/2024.04.05.24304760  0.317
2024 Zhu X, Liu L, Tian S, Zhao G, Zhi E, Chen Q, Zhang F, Zhang A, Tang S, Liu C. Deleterious variant in FAM71D cause male infertility with asthenoteratospermia. Molecular Genetics and Genomics : Mgg. 299: 35. PMID 38489045 DOI: 10.1007/s00438-024-02117-6  0.444
2024 Gao Y, Liu L, Tian S, Liu C, Lv M, Wu H, Tang D, Song B, Shen Q, Xu Y, Zhou P, Wei Z, Zhang F, Cao Y, He X. Whole-exome sequencing identifies ADGB as a novel causative gene for male infertility in humans: from motility to fertilization. Andrology. PMID 38385883 DOI: 10.1111/andr.13605  0.371
2024 Wang Y, Chen J, Huang X, Wu B, Dai P, Zhang F, Li J, Wang L. Gene-knockout by iSTOP enables rapid reproductive disease modeling and phenotyping in germ cells of the founder generation. Science China. Life Sciences. PMID 38332217 DOI: 10.1007/s11427-023-2408-2  0.396
2023 Chen S, Wang L, Chen L, Shi W, Zhang J, Hu Y, Wang Y, Jin L, Sheng J, Zhang F, Wu Y, Huang H, Xu C. A novel preimplantation genetic testing strategy for a subtelomeric genetic disorder: A case study. Genes & Diseases. 11: 101014. PMID 38425427 DOI: 10.1016/j.gendis.2023.05.013  0.315
2023 Zhou Y, Wang Y, Chen J, Wu B, Tang S, Zhang F, Liu C, Wang L. Dnali1 is required for sperm motility and male fertility in mice. Basic and Clinical Andrology. 33: 32. PMID 37993789 DOI: 10.1186/s12610-023-00205-y  0.326
2023 Wang Y, Huang X, Sun G, Chen J, Wu B, Luo J, Tang S, Dai P, Zhang F, Li J, Wang L. Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 37709195 DOI: 10.1016/j.jgg.2023.09.002  0.32
2023 Zhou J, Zhang B, Zeb A, Ma A, Chen J, Zhao D, Rahim F, Khan R, Zhang H, Zhang Y, Khan I, Kakakhel MBS, Khan A, Shah W, Jiang X, ... Zhang F, et al. A recessive ACTL7A founder variant leads to male infertility due to acrosome detachment in Pakistani Pashtuns. Clinical Genetics. PMID 37286336 DOI: 10.1111/cge.14383  0.382
2023 Zhang Y, Huang X, Xu Q, Yu M, Shu M, Shan S, Fan Y, Li S, Tao C, Zhao Y, Ji J, Qin Y, Lu C, Xia Y, Zhang F. Homozygous nonsense variants of KCTD19 cause male infertility in humans and mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 37257643 DOI: 10.1016/j.jgg.2023.05.008  0.303
2023 Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao C, Li C, Kherraf ZE, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, ... ... Zhang F, et al. Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models. American Journal of Human Genetics. PMID 36796361 DOI: 10.1016/j.ajhg.2023.01.016  0.78
2023 Luo W, Ke H, Tang S, Jiao X, Li Z, Zhao S, Zhang F, Guo T, Qin Y. Next-generation sequencing of 500 POI patients identified novel responsible monogenic and oligogenic variants. Journal of Ovarian Research. 16: 39. PMID 36793102 DOI: 10.1186/s13048-023-01104-6  0.313
2023 Ke H, Tang S, Guo T, Hou D, Jiao X, Li S, Luo W, Xu B, Zhao S, Li G, Zhang X, Xu S, Wang L, Wu Y, Wang J, ... Zhang F, et al. Landscape of pathogenic mutations in premature ovarian insufficiency. Nature Medicine. PMID 36732629 DOI: 10.1038/s41591-022-02194-3  0.43
2023 Tian S, Wang Z, Liu L, Zhou Y, Lv Y, Tang D, Wang J, Jiang J, Wu H, Tang S, Wang G, Geng H, Tao F, Liu H, He X, ... Zhang F, et al. A homozygous frameshift mutation in ADAD2 cause male infertility with spermatogenic impairments. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 36608931 DOI: 10.1016/j.jgg.2022.12.004  0.787
2023 Tian S, Tu C, He X, Meng L, Wang J, Tang S, Gao Y, Liu C, Wu H, Zhou Y, Lv M, Lin G, Jin L, Cao Y, Tang D, ... Zhang F, et al. Biallelic mutations in cause male infertility with severe MMAF and NOA. Journal of Medical Genetics. PMID 36593121 DOI: 10.1136/jmg-2022-108887  0.801
2022 Zheng H, Mei S, Li F, Wei L, Wang Y, Huang J, Zhang F, Huang J, Liu Y, Gu W, Liu H. Expansion of the mutation spectrum and phenotype of -related neurodevelopmental disorder. Frontiers in Molecular Neuroscience. 15: 970649. PMID 36466803 DOI: 10.3389/fnmol.2022.970649  0.329
2022 Liu L, Tang SY, Zhang F, Jiang F. A novel homozygous loss-of-function mutation in induces male infertility with nonobstructive azoospermia. Asian Journal of Andrology. PMID 36153927 DOI: 10.4103/aja202272  0.303
2022 Shang L, Ren S, Yang X, Zhang F, Jin L, Zhang X, Wu Y. EIF4ENIF1 variants in two patients with non-syndromic premature ovarian insufficiency. European Journal of Medical Genetics. 104597. PMID 36030004 DOI: 10.1016/j.ejmg.2022.104597  0.38
2022 Khan A, Tian S, Tariq M, Khan S, Safeer M, Ullah N, Akbar N, Javed I, Asif M, Ahmad I, Ullah S, Satti HS, Khan R, Naeem M, Ali M, ... ... Zhang F, et al. NGS-driven molecular diagnosis of heterogeneous hereditary neurological disorders reveals novel and known variants in disease-causing genes. Molecular Genetics and Genomics : Mgg. PMID 36002593 DOI: 10.1007/s00438-022-01945-8  0.771
2022 Yang C, Lin X, Ji Z, Huang Y, Zhang L, Luo J, Chen H, Li P, Tian R, Zhi E, Hong Y, Zhou Z, Zhang F, Li Z, Yao C. Novel bi-allelic variants in KASH5 are associated with meiotic arrest and non-obstructive azoospermia. Molecular Human Reproduction. PMID 35674372 DOI: 10.1093/molehr/gaac021  0.339
2022 Zhang F. "Progressive motility" in elucidating novel genetic causes of male infertility. Asian Journal of Andrology. 24: 229-230. PMID 35532567 DOI: 10.4103/aja202231  0.322
2022 Qin Y, Du Y, Chen L, Liu Y, Xu W, Liu Y, Li Y, Leng J, Wang Y, Zhang XY, Feng J, Zhang F, Jin L, Qiu Z, Gong X, et al. A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling. Molecular Psychiatry. PMID 35388181 DOI: 10.1038/s41380-022-01539-1  0.358
2022 Zhang X, Wang L, Ma Y, Wang Y, Liu H, Liu M, Qin L, Li J, Jiang C, Zhang X, Shan X, Liu Y, Li J, Li Y, Zheng R, ... ... Zhang F, et al. CEP128 is involved in spermatogenesis in humans and mice. Nature Communications. 13: 1395. PMID 35296684 DOI: 10.1038/s41467-022-29109-7  0.336
2022 Cong J, Yang Y, Wang X, Shen Y, Qi HT, Liu C, Tang S, Wu S, Tian S, Zhou Y, He X, Wang L, Liu MF, Zhang F. Deficiency of X-linked TENT5D causes male infertility by disrupting the mRNA stability during spermatogenesis. Cell Discovery. 8: 23. PMID 35256600 DOI: 10.1038/s41421-021-00369-9  0.736
2022 Liu C, Shen Y, Tang S, Wang J, Zhou Y, Tian S, Wu H, Cong J, He X, Jin L, Cao Y, Yang Y, Zhang F. Homozygous variants in induce asthenoteratozoospermia and male infertility. Journal of Medical Genetics. PMID 35228300 DOI: 10.1136/jmedgenet-2021-108271  0.805
2022 Lv M, Liu C, Ma C, Yu H, Shao Z, Gao Y, Liu Y, Wu H, Tang D, Tan Q, Zhang J, Li K, Xu C, Geng H, Zhang J, ... ... Zhang F, et al. Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations. Reproductive Biology and Endocrinology : Rb&E. 20: 5. PMID 34980136 DOI: 10.1186/s12958-021-00880-4  0.349
2021 Wang Y, Chen Q, Zhang F, Yang X, Shang L, Ren S, Pan Y, Zhou Z, Li G, Fang Y, Jin L, Wu Y, Zhang X. Whole exome sequencing identified a rare WT1 loss-of-function variant in a non-syndromic POI patient. Molecular Genetics & Genomic Medicine. e1820. PMID 34845858 DOI: 10.1002/mgg3.1820  0.402
2021 Cong J, Wang X, Amiri-Yekta A, Wang L, Kherraf ZE, Liu C, Cazin C, Tang S, Hosseini SH, Tian S, Daneshipour A, Wang J, Zhou Y, Zeng Y, Yang S, ... ... Zhang F, et al. Homozygous mutations in cause male infertility with oligoasthenoteratozoospermia in humans and mice. Journal of Medical Genetics. PMID 34348960 DOI: 10.1136/jmedgenet-2021-107919  0.802
2021 Tu C, Cong J, Zhang Q, He X, Zheng R, Yang X, Gao Y, Wu H, Lv M, Gu Y, Lu S, Liu C, Tian S, Meng L, Wang W, ... ... Zhang F, et al. Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. American Journal of Human Genetics. PMID 34237282 DOI: 10.1016/j.ajhg.2021.06.010  0.819
2021 Liu C, Shen Y, Shen Q, Zhang W, Wang J, Tang S, Wu H, Tian S, Cong J, He X, Jin L, Zhang F, Jiang X, Cao Y. Novel Mutations in X-Linked, -Induced Asthenoteratozoospermia and Male Infertility. Cells. 10. PMID 34202084 DOI: 10.3390/cells10071594  0.818
2021 Zhou Z, Yang X, Pan Y, Shang L, Chen S, Yang J, Jin L, Zhang F, Wu Y. Temporal transcriptomic landscape of postnatal mouse ovaries reveals dynamic gene signatures associated with ovarian aging. Human Molecular Genetics. PMID 34137841 DOI: 10.1093/hmg/ddab163  0.371
2021 Li G, Yang X, Wang L, Pan Y, Chen S, Shang L, Zhang Y, Wu Y, Zhou Z, Chen Q, Zhang X, Zhang L, Wang Y, Li J, Jin L, ... ... Zhang F, et al. Haploinsufficiency in non-homologous end joining factor 1 induces ovarian dysfunction in humans and mice. Journal of Medical Genetics. PMID 33888552 DOI: 10.1136/jmedgenet-2020-107398  0.395
2021 Gao Y, Tian S, Sha Y, Zha X, Cheng H, Wang A, Liu C, Lv M, Ni X, Li Q, Wu H, Tan Q, Tang D, Song B, Ding D, ... ... Zhang F, et al. Novel bi-allelic variants in DNAH2 cause severe asthenoteratozoospermia with multiple morphological abnormalities of the flagella. Reproductive Biomedicine Online. PMID 33771466 DOI: 10.1016/j.rbmo.2021.01.011  0.779
2021 Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, ... ... Zhang F, et al. Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility. American Journal of Human Genetics. PMID 33472045 DOI: 10.1016/j.ajhg.2021.01.002  0.831
2021 Chen N, Zhao S, Jolly A, Wang L, Pan H, Yuan J, Chen S, Koch A, Ma C, Tian W, Jia Z, Kang J, Zhao L, Qin C, Fan X, ... ... Zhang F, et al. Perturbations of genes essential for Müllerian duct and Wölffian duct development in Mayer-Rokitansky-Küster-Hauser syndrome. American Journal of Human Genetics. PMID 33434492 DOI: 10.1016/j.ajhg.2020.12.014  0.471
2020 Zhang B, Khan I, Liu C, Ma A, Khan A, Zhang Y, Huan Z, Kakakhel MBS, Zhou J, Zhang W, Li Y, Ali A, Jiang X, Murtaza G, Khan R, ... ... Zhang F, et al. Novel loss-of-function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice. Clinical Genetics. PMID 33070343 DOI: 10.1111/cge.13866  0.349
2020 Pan Y, Yang X, Zhang F, Chen S, Zhou Z, Yin H, Ma H, Shang L, Yang J, Li G, Wang Y, Jin L, Shi Q, Wu Y. A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice. Molecular Genetics and Genomics : Mgg. PMID 33025164 DOI: 10.1007/s00438-020-01730-5  0.465
2020 Xin A, Qu R, Chen G, Zhang L, Chen J, Tao C, Fu J, Tang J, Ru Y, Chen Y, Peng X, Shi H, Zhang F, Sun X. Disruption in causes acrosomal ultrastructural defects in human and mouse sperm as a novel male factor inducing early embryonic arrest. Science Advances. 6: eaaz4796. PMID 32923619 DOI: 10.1126/Sciadv.Aaz4796  0.368
2020 Yao C, Yang C, Zhao L, Li P, Tian R, Chen H, Guo Y, Huang Y, Zhi E, Zhai J, Sun H, Zhang J, Hong Y, Zhang L, Ji Z, ... Zhang F, et al. Bi-allelic loss-of-function mutations cause meiotic arrest and non-obstructive azoospermia. Journal of Medical Genetics. PMID 32900840 DOI: 10.1136/Jmedgenet-2020-107042  0.349
2020 Liu L, Liu W, Shi Y, Li L, Gao Y, Lei Y, Finnell R, Zhang T, Zhang F, Jin L, Li H, Tao W, Wang H. DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 32900645 DOI: 10.1016/J.Jgg.2020.06.003  0.423
2020 Gao L, Altae-Tran H, Böhning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F. Diverse enzymatic activities mediate antiviral immunity in prokaryotes. Science (New York, N.Y.). 369: 1077-1084. PMID 32855333 DOI: 10.1126/Science.Aba0372  0.323
2020 Li P, Ning Y, Wang W, Guo X, Poulet B, Wang X, Wen Y, Han J, Hao J, Liang X, Liu L, Du Y, Cheng B, Cheng S, Zhang L, ... ... Zhang F, et al. The integrative analysis of DNA methylation and mRNA expression profiles confirmed the role of selenocompound metabolism pathway in Kashin-Beck disease. Cell Cycle (Georgetown, Tex.). 1-16. PMID 32816579 DOI: 10.1080/15384101.2020.1807665  0.307
2020 He X, Liu C, Yang X, Lv M, Ni X, Li Q, Cheng H, Liu W, Tian S, Wu H, Gao Y, Yang C, Tan Q, Cong J, Tang D, ... ... Zhang F, et al. Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice. American Journal of Human Genetics. PMID 32791035 DOI: 10.1016/J.Ajhg.2020.07.010  0.815
2020 Weiss T, Wang C, Kang X, Zhao H, Gamo ME, Starker CG, Crisp PA, Zhou P, Springer NM, Voytas DF, Zhang F. Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis. The Plant Journal : For Cell and Molecular Biology. PMID 32786122 DOI: 10.1111/Tpj.14949  0.366
2020 Cheng B, Qi X, Liang C, Zhang L, Ma M, Li P, Liu L, Cheng S, Yao Y, Chu X, Ye J, Wen Y, Jia Y, Zhang F. Integrative Genomic Enrichment Analysis Identified the Brain Regions and Development Stages Related to Anorexia Nervosa and Obsessive-Compulsive Disorder. Cerebral Cortex (New York, N.Y. : 1991). PMID 32770201 DOI: 10.1093/Cercor/Bhaa214  0.303
2020 Jin S, Fei H, Zhu Z, Luo Y, Liu J, Gao S, Zhang F, Chen YH, Wang Y, Gao C. Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity. Molecular Cell. PMID 32721385 DOI: 10.1016/J.Molcel.2020.07.005  0.322
2020 Chen Q, Ke H, Luo X, Wang L, Wu Y, Tang S, Li J, Jin L, Zhang F, Qin Y, Chen X. Rare deleterious BUB1B variants induce premature ovarian insufficiency and early menopause. Human Molecular Genetics. PMID 32716490 DOI: 10.1093/Hmg/Ddaa153  0.545
2020 Cheng B, Ning Y, Liang C, Li P, Liu L, Cheng S, Ma M, Zhang L, Xin Q, Wen Y, Zhang F. Genome-Wide Association Analysis Identified ANXA1 Associated with Shoulder Impingement Syndrome in UK Biobank Samples. G3 (Bethesda, Md.). PMID 32690583 DOI: 10.1534/G3.120.401257  0.318
2020 Liu C, Miyata H, Gao Y, Sha Y, Tang S, Xu Z, Whitfield M, Patrat C, Wu H, Dulioust E, Tian S, Shimada K, Cong J, Noda T, Li H, ... ... Zhang F, et al. Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility. American Journal of Human Genetics. PMID 32619401 DOI: 10.1016/J.Ajhg.2020.06.004  0.822
2020 Gussow AB, Auslander N, Faure G, Wolf YI, Zhang F, Koonin EV. Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32522874 DOI: 10.1073/Pnas.2008176117  0.312
2020 Yang N, Wu N, Dong S, Zhang L, Zhao Y, Chen W, Du R, Song C, Ren X, Liu J, Pehlivan D, Liu Z, Jia R, Wang C, Zhao S, ... ... Zhang F, et al. Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome. Kidney International. PMID 32450157 DOI: 10.1016/J.Kint.2020.04.045  0.561
2020 Qi X, Yu F, Wen Y, Li P, Cheng B, Ma M, Cheng S, Zhang L, Liang C, Liu L, Zhang F. Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis. Bone & Joint Research. 9: 130-138. PMID 32435465 DOI: 10.1302/2046-3758.93.Bjr-2019-0137.R1  0.324
2020 Zhao S, Zhang Y, Chen W, Li W, Wang S, Wang L, Zhao Y, Lin M, Ye Y, Lin J, Zheng Y, Liu J, Zhao H, Yan Z, Yang Y, ... ... Zhang F, et al. Diagnostic yield and clinical impact of exome sequencing in early-onset scoliosis (EOS). Journal of Medical Genetics. PMID 32381727 DOI: 10.1136/Jmedgenet-2019-106823  0.326
2020 Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H. Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects. Human Mutation. PMID 32333458 DOI: 10.1002/Humu.24028  0.523
2020 Ni X, Wang J, Lv M, Liu C, Zhong Y, Tian S, Wu H, Cheng H, Gao Y, Tan Q, Chen B, Li Q, Song B, Wei Z, Zhou P, ... ... Zhang F, et al. A novel homozygous mutation in WDR19 induces disorganization of microtubules in sperm flagella and nonsyndromic asthenoteratospermia. Journal of Assisted Reproduction and Genetics. PMID 32323121 DOI: 10.1007/S10815-020-01770-1  0.79
2020 Wu H, Gao Y, Ma C, Shen Q, Wang J, Lv M, Liu C, Cheng H, Zhu F, Tian S, Elshewy N, Ni X, Tan Q, Xu X, Zhou P, ... ... Zhang F, et al. A novel hemizygous loss-of-function mutation in ADGRG2 causes male infertility with congenital bilateral absence of the vas deferens. Journal of Assisted Reproduction and Genetics. PMID 32314195 DOI: 10.1007/S10815-020-01779-6  0.78
2020 Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Highly Parallel Profiling of Cas9 Variant Specificity. Molecular Cell. PMID 32187529 DOI: 10.1016/J.Molcel.2020.02.023  0.356
2020 Cheng B, Liang C, Li P, Liu L, Cheng S, Ma M, Zhang L, Qi X, Wen Y, Zhang F. Evaluating the Genetic Correlations Between Left-Handedness and Mental Disorder Using Linkage Disequilibrium Score Regression and Transcriptome-Wide Association Study. Biochemical Genetics. PMID 32100139 DOI: 10.1007/S10528-020-09952-3  0.338
2020 Sun X, Ding Y, Orr MC, Zhang F. Streamlining universal single-copy ortholog and ultraconserved element design: a case study in Collembola. Molecular Ecology Resources. PMID 32065730 DOI: 10.1111/1755-0998.13146  0.343
2020 Lv M, Liu W, Chi W, Ni X, Wang J, Cheng H, Li WY, Yang S, Wu H, Zhang J, Gao Y, Liu C, Li C, Yang C, Tan Q, ... ... Zhang F, et al. Homozygous mutations in can induce asthenoteratospermia with severe MMAF. Journal of Medical Genetics. PMID 32051257 DOI: 10.1136/Jmedgenet-2019-106479  0.539
2020 Qi X, Wen Y, Li P, Liang C, Cheng B, Ma M, Cheng S, Zhang L, Liu L, Kafle OP, Zhang F. An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder. International Journal of Bipolar Disorders. 8: 6. PMID 32009227 DOI: 10.1186/S40345-019-0170-Z  0.308
2020 Cheng S, Ma M, Zhang L, Liu L, Cheng B, Qi X, Liang C, Li P, Kafle OP, Wen Y, Zhang F. CGSEA: A Flexible Tool for Evaluating the Associations of Chemicals with Complex Diseases. G3 (Bethesda, Md.). PMID 31937547 DOI: 10.1534/G3.119.400945  0.318
2019 Xie Y, Wang Q, Gao N, Wu F, Lan F, Zhang F, Jin L, Huang Z, Ge J, Wang H, Wang Y. MircroRNA-10b Promotes Human Embryonic Stem Cell-Derived Cardiomyocyte Proliferation via Novel Target Gene LATS1. Molecular Therapy. Nucleic Acids. 19: 437-445. PMID 31902743 DOI: 10.1016/J.Omtn.2019.11.026  0.338
2019 Ren X, Yang N, Wu N, Xu X, Chen W, Zhang L, Li Y, Du RQ, Dong S, Zhao S, Chen S, Jiang LP, Wang L, Zhang J, Wu Z, ... ... Zhang F, et al. Increased gene dosages induce congenital cervical vertebral malformations in humans and mice. Journal of Medical Genetics. PMID 31888956 DOI: 10.1136/Jmedgenet-2019-106333  0.555
2019 El-Battrawy I, Müller J, Zhao Z, Cyganek L, Zhong R, Zhang F, Kleinsorge M, Lan H, Li X, Xu Q, Huang M, Liao Z, Moscu-Gregor A, Albers S, Dinkel H, et al. Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Frontiers in Cell and Developmental Biology. 7: 261. PMID 31737628 DOI: 10.3389/fcell.2019.00261  0.306
2019 Liu C, He X, Liu W, Yang S, Wang L, Li W, Wu H, Tang S, Ni X, Wang J, Gao Y, Tian S, Zhang L, Cong J, Zhang Z, ... ... Zhang F, et al. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics. PMID 31735294 DOI: 10.1016/J.Ajhg.2019.10.010  0.819
2019 Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F. A Survey of Genome Editing Activity for 16 Cas12a Orthologs. The Keio Journal of Medicine. PMID 31723075 DOI: 10.2302/Kjm.2019-0009-Oa  0.304
2019 Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, ... ... Zhang F, et al. A missense variant causes flagella destabilization and asthenozoospermia. The Journal of Experimental Medicine. PMID 31658987 DOI: 10.1084/Jem.20182365  0.398
2019 Zhang L, Du Y, Wen Y, Ma M, Cheng S, Cheng B, Li P, Qi X, Liang C, Liu L, Liang X, Guo X, Zhang F. Integrating transcriptome-wide association study and mRNA expression profiling identified candidate genes and pathways associated with osteomyelitis. Scandinavian Journal of Rheumatology. 1-6. PMID 31657276 DOI: 10.1080/03009742.2019.1653492  0.333
2019 Wang L, Zhang Y, Fu X, Dong S, Tang S, Zhang N, Song C, Yang N, Zhang L, Wang H, Shi H, Jin L, Zhang F, Li J, Hua K. Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies. Cell Research. PMID 31628433 DOI: 10.1038/S41422-019-0243-7  0.339
2019 Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, et al. Rare variants in FANCA induce premature ovarian insufficiency. Human Genetics. PMID 31535215 DOI: 10.1007/S00439-019-02059-9  0.579
2019 Li W, Wu H, Li F, Tian S, Kherraf ZE, Zhang J, Ni X, Lv M, Liu C, Tan Q, Shen Y, Amiri-Yekta A, Cazin C, Zhang J, Liu W, ... ... Zhang F, et al. Biallelic mutations in cause male infertility with multiple morphological abnormalities of the sperm flagella in humans and mice. Journal of Medical Genetics. PMID 31501240 DOI: 10.1136/Jmedgenet-2019-106344  0.814
2019 Chen W, Lin J, Wang L, Li X, Zhao S, Liu J, Akdemir ZC, Zhao Y, Du R, Ye Y, Song X, Zhang Y, Yan Z, Yang X, Lin M, ... Zhang F, et al. TBX6 missense variants expand the mutational spectrum in a non-Mendelian inheritance disease. Human Mutation. PMID 31471994 DOI: 10.1002/Humu.23907  0.578
2019 Hijazi H, Coelho FS, Gonzaga-Jauregui C, Bernardini L, Mar SS, Manning MA, Hanson-Kahn A, Naidu S, Srivastava S, Lee JA, Jones JR, Friez MJ, Alberico T, Torres B, Fang P, ... Zhang F, et al. Xq22 deletions and correlation with distinct neurological disease traits in females: further evidence for a contiguous gene syndrome. Human Mutation. PMID 31448840 DOI: 10.1002/Humu.23902  0.57
2019 Qi X, Guan F, Wen Y, Li P, Ma M, Cheng S, Zhang L, Liang C, Cheng B, Zhang F. Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109736. PMID 31425724 DOI: 10.1016/J.Pnpbp.2019.109736  0.331
2019 Li P, Wu C, Guo X, Wen Y, Liu L, Liang X, Du Y, Zhang L, Ma M, Cheng S, Cheng B, Wang S, Zhang F. Integrative Analysis of Genome-Wide Association Studies and DNA Methylation Profile Identified Genetic Control Genes of DNA Methylation for Kashin-Beck Disease. Cartilage. 1947603519858748. PMID 31220921 DOI: 10.1177/1947603519858748  0.312
2019 Zhang L, Liu L, Ma M, Cheng S, Cheng B, Li P, Wen Y, Du Y, Liang X, Zhao Y, Ding M, Xin Q, Liang C, Huang H, Zhang F. Integrative analysis of transcriptome-wide association study data and mRNA expression profiles identified candidate genes and pathways associated with atrial fibrillation. Heart and Vessels. PMID 31065785 DOI: 10.1007/S00380-019-01418-W  0.323
2019 Liu C, Lv M, He X, Zhu Y, Amiri-Yekta A, Li W, Wu H, Kherraf ZE, Liu W, Zhang J, Tan Q, Tang S, Zhu YJ, Zhong Y, Li C, ... ... Zhang F, et al. Homozygous mutations in induce multiple morphological abnormalities of the sperm flagella and male infertility. Journal of Medical Genetics. PMID 31048344 DOI: 10.1136/Jmedgenet-2019-106011  0.819
2019 Cheng B, Liang X, Wen Y, Li P, Zhang L, Ma M, Cheng S, Du Y, Liu L, Ding M, Zhao Y, Zhang F. Integrative analysis of transcriptome-wide association study data and messenger RNA expression profiles identified candidate genes and pathways for inflammatory bowel disease. Journal of Cellular Biochemistry. PMID 31009124 DOI: 10.1002/Jcb.28744  0.327
2019 Liu W, He X, Yang S, Zouari R, Wang J, Wu H, Kherraf ZE, Liu C, Coutton C, Zhao R, Tang D, Tang S, Lv M, Fang Y, Li W, ... Zhang F, et al. Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics. PMID 30929735 DOI: 10.1016/J.Ajhg.2019.02.020  0.606
2019 Zhang L, Xu X, Sun K, Sun J, Wang Y, Liu Y, Yang N, Tao C, Cai B, Shi G, Zhang F, Shi J. A de novo mutation in DHD domain of SKI causing spina bifida with no craniofacial malformation or intellectual disability. American Journal of Medical Genetics. Part A. PMID 30883014 DOI: 10.1002/Ajmg.A.61088  0.314
2019 Li Z, Zhang F, Wang Y, Qiu Y, Wu Y, Lu Y, Yang L, Qu WJ, Wang H, Zhou W, Tian W. PhenoPro: a novel toolkit for assisting in the diagnosis of Mendelian disease. Bioinformatics (Oxford, England). PMID 30843052 DOI: 10.1093/Bioinformatics/Btz100  0.307
2019 Jin S, Zong Y, Gao Q, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu JL, Zhang F, Gao C. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science (New York, N.Y.). PMID 30819931 DOI: 10.1126/Science.Aaw7166  0.366
2019 Coutton C, Martinez G, Kherraf ZE, Amiri-Yekta A, Boguenet M, Saut A, He X, Zhang F, Cristou-Kent M, Escoffier J, Bidart M, Satre V, Conne B, Fourati Ben Mustapha S, Halouani L, et al. Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice. American Journal of Human Genetics. PMID 30686508 DOI: 10.1016/J.Ajhg.2018.12.013  0.404
2019 Shen Y, Zhang F, Li F, Jiang X, Yang Y, Li X, Li W, Wang X, Cheng J, Liu M, Zhang X, Yuan G, Pei X, Cai K, Hu F, et al. Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella. Nature Communications. 10: 433. PMID 30683861 DOI: 10.1038/S41467-018-08182-X  0.389
2019 Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Engineering of CRISPR-Cas12b for human genome editing. Nature Communications. 10: 212. PMID 30670702 DOI: 10.1038/S41467-018-08224-4  0.357
2019 Zhang F, Ding Y, Zhou QS, Wu J, Luo A, Zhu CD. A high-quality draft genome assembly of Sinella curviseta, a soil model organism (Collembola). Genome Biology and Evolution. PMID 30668671 DOI: 10.1093/Gbe/Evz013  0.333
2019 Liu J, Wu N, Yang N, Takeda K, Chen W, Li W, Du R, Liu S, Zhou Y, Zhang L, Liu Z, Zuo Y, Zhao S, Blank R, ... ... Zhang F, et al. TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30636772 DOI: 10.1038/s41436-018-0377-x  0.455
2019 Dong S, Wang C, Li X, Shen Q, Fu X, Wu M, Song C, Yang N, Wu Y, Wang H, Jin L, Xu H, Zhang F. Noncoding rare variants of TBX6 in congenital anomalies of the kidney and urinary tract. Molecular Genetics and Genomics : Mgg. PMID 30604070 DOI: 10.1007/S00438-018-1522-6  0.508
2019 Wang Q, Li D, Cai B, Chen Q, Li C, Wu Y, Jin L, Wang X, Zhang X, Zhang F. Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype-phenotype correlations. Human Genetics. PMID 30603774 DOI: 10.1007/S00439-018-1962-4  0.549
2019 Verbitsky M, Westland R, Perez A, Kiryluk K, Liu Q, Krithivasan P, Mitrotti A, Fasel DA, Batourina E, Sampson MG, Bodria M, Werth M, Kao C, Martino J, Capone VP, ... ... Zhang F, et al. The copy number variation landscape of congenital anomalies of the kidney and urinary tract. Nature Genetics. 51: 117-127. PMID 30578417 DOI: 10.1038/S41588-018-0281-Y  0.304
2018 Wu H, Li W, He X, Liu C, Fang Y, Zhu F, Jiang H, Liu W, Song B, Wang X, Zhou P, Wei Z, Zhang F, Cao Y. NovelCFAP43 andCFAP44 mutations cause male infertility with multiple morphological abnormalities of the sperm flagella (MMAF). Reproductive Biomedicine Online. PMID 30904354 DOI: 10.1016/J.Rbmo.2018.12.037  0.364
2018 Liu W, Wu H, Wang L, Yang X, Liu C, He X, Li W, Wang J, Chen Y, Wang H, Gao Y, Tang S, Yang S, Jin L, Zhang F, et al. Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 30745215 DOI: 10.1016/J.Jgg.2018.09.006  0.451
2018 Huang H, Cheng S, Ding M, Wen Y, Ma M, Zhang L, Li P, Cheng B, Liang X, Liu L, Du Y, Zhao Y, Kafle OP, Han B, Zhang F. Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identifies Candidate Genes Associated With Autism Spectrum Disorders. Autism Research : Official Journal of the International Society For Autism Research. PMID 30561910 DOI: 10.1002/Aur.2048  0.33
2018 He X, Li W, Wu H, Lv M, Liu W, Liu C, Zhu F, Li C, Fang Y, Yang C, Cheng H, Zhang J, Tan J, Chen T, Tang D, ... Zhang F, et al. Novel homozygous mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella. Journal of Medical Genetics. PMID 30415212 DOI: 10.1136/Jmedgenet-2018-105486  0.607
2018 Gao K, Zhang Y, Zhang L, Kong W, Xie H, Wang J, Wu Y, Wu X, Liu X, Zhang Y, Zhang F, Yu AC, Jiang Y. Large De Novo Microdeletion in Epilepsy with Intellectual and Developmental Disabilities, with a Systems Biology Analysis. Advances in Neurobiology. 21: 247-266. PMID 30334225 DOI: 10.1007/978-3-319-94593-4_9  0.319
2018 Li W, He X, Yang S, Liu C, Wu H, Liu W, Lv M, Tang D, Tan J, Tang S, Chen Y, Wang J, Zhang Z, Wang H, Jin L, Zhang F, et al. Biallelic mutations of CFAP251 cause sperm flagellar defects and human male infertility. Journal of Human Genetics. PMID 30310178 DOI: 10.1038/S10038-018-0520-1  0.622
2018 Yang N, Wu N, Zhang L, Zhao Y, Liu J, Liang X, Ren X, Li W, Chen W, Dong S, Zhao S, Lin J, Xiang H, Xue H, Chen L, ... Zhang F, et al. TBX6 compound inheritance leads to congenital vertebral malformations in humans and mice. Human Molecular Genetics. PMID 30307510 DOI: 10.1093/Hmg/Ddy358  0.627
2018 Ge L, Liu A, Gao K, Du R, Ding J, Mao B, Hua Y, Zhang X, Tan D, Yang H, Fu X, Fan Y, Zhang L, Song S, Wu J, ... Zhang F, et al. Deletion of exon 4 in LAMA2 is the most frequent mutation in Chinese patients with laminin α2-related muscular dystrophy. Scientific Reports. 8: 14989. PMID 30301903 DOI: 10.1038/s41598-018-33098-3  0.313
2018 Du Y, Ning Y, Wen Y, Liu L, Liang X, Li P, Ding M, Zhao Y, Cheng B, Ma M, Zhang L, Cheng S, Yu W, Hu S, Guo X, ... Zhang F, et al. A genome-wide pathway enrichment analysis identifies brain region related biological pathways associated with intelligence. Psychiatry Research. 268: 238-242. PMID 30071386 DOI: 10.1016/J.Psychres.2018.07.029  0.306
2018 Liu J, Zhou Y, Liu S, Song X, Yang XZ, Fan Y, Chen W, Akdemir ZC, Yan Z, Zuo Y, Du R, Liu Z, Yuan B, Zhao S, Liu G, ... ... Zhang F, et al. The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. Human Genetics. PMID 30019117 DOI: 10.1007/s00439-018-1910-3  0.438
2018 He A, Ning Y, Wen Y, Cai Y, Xu K, Cai Y, Han J, Liu L, Du Y, Liang X, Li P, Fan Q, Hao J, Wang X, Guo X, ... ... Zhang F, et al. Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage. Bone & Joint Research. 7: 343-350. PMID 29922454 DOI: 10.1302/2046-3758.75.Bjr-2017-0284.R1  0.335
2018 Ding M, Li P, Wen Y, Zhao Y, Cheng B, Zhang L, Ma M, Cheng S, Liu L, Du Y, Liang X, He A, Guo X, Zhang F. Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29883697 DOI: 10.1016/J.Pnpbp.2018.05.026  0.32
2018 Myers SA, Wright J, Peckner R, Kalish BT, Zhang F, Carr SA. Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling. Nature Methods. PMID 29735997 DOI: 10.1038/S41592-018-0007-1  0.347
2018 Liu Z, Liu J, Liu G, Cao W, Liu S, Chen Y, Zuo Y, Chen W, Chen J, Zhang Y, Huang S, Qiu G, Giampietro PF, Zhang F, Wu Z, et al. Phenotypic heterogeneity of intellectual disability in patients with congenital insensitivity to pain with anhidrosis: A case report and literature review. The Journal of International Medical Research. 300060517747164. PMID 29619836 DOI: 10.1177/0300060517747164  0.321
2018 Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science Advances. 4: eaao5508. PMID 29503867 DOI: 10.1126/Sciadv.Aao5508  0.322
2018 Zhang F, Voytas DF. Modulating gene translational control through genome editing National Science Review. 6: 391-391. DOI: 10.1093/Nsr/Nwy123  0.324
2017 Fan H, Lv P, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang Q, Zhang L, Zhang F, Zheng X, Wu H, Wen B. The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. Genome Research. PMID 29273625 DOI: 10.1101/Gr.224576.117  0.323
2017 He A, Wang W, Prakash NT, Tinkov AA, Skaln AV, Wen Y, Hao J, Guo X, Zhang F. Integrating genome-wide association study summaries and element-gene interaction datasets identified multiple associations between elements and complex diseases. Genetic Epidemiology. PMID 29265413 DOI: 10.1002/Gepi.22106  0.312
2017 Jiang Q, Liu F, Miao C, Li Q, Zhang Z, Xiao P, Su L, Yu K, Chen X, Zhang F, Chakravarti A, Li L. RET somatic mutations are underrecognized in Hirschsprung disease. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 29261189 DOI: 10.1038/Gim.2017.178  0.348
2017 Zhao Y, He A, Zhu F, Ding M, Hao J, Fan Q, Li P, Liu L, Du Y, Liang X, Guo X, Zhang F, Ma X. Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29024729 DOI: 10.1016/J.Pnpbp.2017.10.003  0.315
2017 Wang W, Huang S, Hou W, Liu Y, Fan Q, He A, Wen Y, Hao J, Guo X, Zhang F. Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density. Bone & Joint Research. 6: 572-576. PMID 28978616 DOI: 10.1302/2046-3758.610.Bjr-2017-0113.R1  0.353
2017 Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973933 DOI: 10.1073/Pnas.1706193114  0.347
2017 Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature Neuroscience. PMID 28805815 DOI: 10.1038/Nn.4620  0.356
2017 Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. PMID 28792927 DOI: 10.1038/Nature23451  0.347
2017 Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, ... ... Zhang F, et al. Identification of essential genes for cancer immunotherapy. Nature. PMID 28783722 DOI: 10.1038/Nature23477  0.329
2017 Wang F, Liu D, Zhang RR, Yu LW, Zhao JY, Yang XY, Jiang SS, Ma D, Qiao B, Zhang F, Jin L, Gui YH, Wang HY. A TBX5 3'UTR variant increases the risk of congenital heart disease in the Han Chinese population. Cell Discovery. 3: 17026. PMID 28761722 DOI: 10.1038/Celldisc.2017.26  0.409
2017 Scott DA, Zhang F. Implications of human genetic variation in CRISPR-based therapeutic genome editing. Nature Medicine. PMID 28759051 DOI: 10.1038/Nm.4377  0.368
2017 Liang X, He A, Wang W, Liu L, Du Y, Fan Q, Li P, Wen Y, Hao J, Guo X, Zhang F. Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes and Gene Sets Associated with Diabetes. Biomed Research International. 2017: 1758636. PMID 28744461 DOI: 10.1155/2017/1758636  0.309
2017 Zhang C, Lu J, Lou H, Du R, Xu S, Shen Y, Zhang F, Jin L. CNVbase: Batch identification of novel and rare copy number variations based on multi-ethnic population data. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 28739046 DOI: 10.1016/J.Jgg.2017.07.001  0.407
2017 Lu J, Lou H, Fu R, Lu D, Zhang F, Wu Z, Zhang X, Li C, Fang B, Pu F, Wei J, Wei Q, Zhang C, Wang X, Lu Y, et al. Assessing genome-wide copy number variation in the Han Chinese population. Journal of Medical Genetics. PMID 28705883 DOI: 10.1136/Jmedgenet-2017-104613  0.487
2017 Hu W, Chen M, Ji J, Qin Y, Zhang F, Xu M, Wu W, Du G, Wu D, Han X, Jin L, Xia Y, Lu C, Wang X. Interaction between Y chromosome haplogroup O3(*) and 4-n-octylphenol exposure reduces the susceptibility to spermatogenic impairment in Han Chinese. Ecotoxicology and Environmental Safety. 144: 450-455. PMID 28667856 DOI: 10.1016/J.Ecoenv.2017.06.038  0.421
2017 Du Y, Wen Y, Guo X, Hao J, Wang W, He A, Fan Q, Li P, Liu L, Liang X, Zhang F. A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis. Cellular and Molecular Neurobiology. PMID 28639078 DOI: 10.1007/S10571-017-0512-2  0.346
2017 Nishimasu H, Yamano T, Gao L, Zhang F, Ishitani R, Nureki O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Molecular Cell. PMID 28595896 DOI: 10.1016/J.Molcel.2017.04.019  0.308
2017 Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Engineered Cpf1 variants with altered PAM specificities. Nature Biotechnology. PMID 28581492 DOI: 10.1038/Nbt.3900  0.36
2017 Fan Q, Wang W, Hao J, He A, Wen Y, Guo X, Wu C, Ning Y, Wang X, Wang S, Zhang F. Integrating genome-wide association study and expression quantitative trait loci data identifies multiple genes and gene set associated with neuroticism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28552732 DOI: 10.1016/J.Pnpbp.2017.05.017  0.352
2017 Tang S, Wang X, Li W, Yang X, Li Z, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, ... ... Zhang F, et al. Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella. American Journal of Human Genetics. PMID 28552195 DOI: 10.1016/J.Ajhg.2017.04.012  0.641
2017 Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks. Nature Communications. 8: 15058. PMID 28497783 DOI: 10.1038/Ncomms15058  0.318
2017 Boycott KM, Rath A, Chong JX, Hartley T, Alkuraya FS, Baynam G, Brookes AJ, Brudno M, Carracedo A, den Dunnen JT, Dyke SOM, Estivill X, Goldblatt J, Gonthier C, Groft SC, ... ... Zhang F, et al. International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases. American Journal of Human Genetics. 100: 695-705. PMID 28475856 DOI: 10.1016/J.Ajhg.2017.04.003  0.319
2017 Dong Z, Li Y, Zhou J, Jiang S, Wang Y, Chen Y, Zhao D, Yang C, Qian Q, Ma Y, He H, Ji H, Yang Y, Wang X, Xu X, ... ... Zhang F, et al. Copy number variants of ABCF1, IL17REL, and FCGR3A are associated with the risk of gout. Protein & Cell. PMID 28405828 DOI: 10.1007/S13238-017-0401-Y  0.403
2017 Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F. Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits. Cell Reports. 19: 335-350. PMID 28402856 DOI: 10.1016/J.Celrep.2017.03.052  0.323
2017 Yan G, Qiao R, Zhang F, Xin W, Xiao S, Huang T, Zhang Z, Huang L. Imputation-Based Whole-Genome Sequence Association Study Rediscovered the Missing QTL for Lumbar Number in Sutai Pigs. Scientific Reports. 7: 615. PMID 28377593 DOI: 10.1038/s41598-017-00729-0  0.32
2017 Zhang L, Wang J, Zhang C, Li D, Carvalho CM, Ji H, Xiao J, Wu Y, Zhou W, Wang H, Jin L, Luo Y, Wu X, Lupski JR, Zhang F, et al. Efficient CNV breakpoint analysis reveals unexpected structural complexity and correlation of dosage-sensitive genes with clinical severity in genomic disorders. Human Molecular Genetics. PMID 28334874 DOI: 10.1093/Hmg/Ddx102  0.592
2017 Fan Q, Zhang F, Wang W, Xu J, Hao J, He A, Wen Y, Li P, Liang X, Du Y, Liu L, Wu C, Wang S, Wang X, Ning Y, et al. GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures. Briefings in Bioinformatics. PMID 28334273 DOI: 10.1093/Bib/Bbx025  0.321
2017 Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, ... ... Zhang F, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. PMID 28241139 DOI: 10.1038/Nature21688  0.34
2017 Liu P, Yuan B, Carvalho CM, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, ... Zhang F, et al. An Organismal CNV Mutator Phenotype Restricted to Early Human Development. Cell. 168: 830-842.e7. PMID 28235197 DOI: 10.1016/J.Cell.2017.01.037  0.56
2017 Hao J, Wang W, Wen Y, Xiao X, He A, Wu C, Wang S, Guo X, Zhang F. Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease. Scientific Reports. 7: 40020. PMID 28059113 DOI: 10.1038/Srep40020  0.345
2016 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. PMID 27918548 DOI: 10.1038/Nbt.3737  0.344
2016 Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224  0.319
2016 Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7: 13330. PMID 27804970 DOI: 10.1038/Ncomms13330  0.32
2016 Wu C, Wen Y, Guo X, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW, Zhang F. Genetic association, mRNA and protein expression analysis identify ATG4C as a susceptibility gene for Kashin-Beck disease. Osteoarthritis and Cartilage. PMID 27742532 DOI: 10.1016/J.Joca.2016.09.019  0.34
2016 Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C, Regev A, Zhang F. High-resolution interrogation of functional elements in the noncoding genome. Science (New York, N.Y.). 353: 1545-1549. PMID 27708104 DOI: 10.1126/Science.Aaf7613  0.352
2016 Wang W, Hao J, Zheng S, Fan Q, He A, Wen Y, Guo X, Wu C, Wang S, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW, ... Zhang F, et al. Tissue-specific pathway association analysis using genome-wide association study summaries. Bioinformatics (Oxford, England). PMID 27651483 DOI: 10.1093/Bioinformatics/Btw595  0.326
2016 Shi XW, Shi BH, Lyu AL, Zhang F, Zhou TT, Guo X. Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips. Biomedical and Environmental Sciences : Bes. 29: 539-43. PMID 27554126 DOI: 10.3967/Bes2016.072  0.308
2016 Hao J, Wang W, Wen Y, Xiao X, He A, Guo X, Yang T, Liu X, Shen H, Chen X, Tian Q, Deng HW, Zhang F. A bivariate genome-wide association study identifies ADAM12 as a novel susceptibility gene for Kashin-Beck disease. Scientific Reports. 6: 31792. PMID 27545300 DOI: 10.1038/Srep31792  0.337
2016 Chen W, Liu J, Yuan D, Zuo Y, Liu Z, Liu S, Zhu Q, Qiu G, Huang S, Giampietro PF, Zhang F, Wu N, Wu Z. Progress and perspective of TBX6 gene in congenital vertebral malformations. Oncotarget. PMID 27437870 DOI: 10.18632/Oncotarget.10619  0.352
2016 Dong X, Wang X, Zhang F, Tian W. Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome. Molecular Biology and Evolution. PMID 27401230 DOI: 10.1093/Molbev/Msw128  0.359
2016 Guan J, Wang D, Cao W, Zhao Y, Du R, Yuan H, Liu Q, Lan L, Zong L, Yang J, Yin Z, Han B, Zhang F, Wang Q. SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans. Journal of Human Genetics. PMID 27383657 DOI: 10.1038/Jhg.2016.86  0.384
2016 Wang W, Liu Y, Hao J, Zheng S, Wen Y, Xiao X, He A, Fan Q, Zhang F, Liu R. Comparative analysis of gene expression profiles of hip articular cartilage between non-traumatic necrosis and osteoarthritis. Gene. PMID 27374150 DOI: 10.1016/J.Gene.2016.06.058  0.303
2016 Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H. The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells. The Journal of Biological Chemistry. PMID 27246850 DOI: 10.1074/Jbc.M116.729467  0.325
2016 Zhu XB, Lu JQ, Zhi EL, Zhu Y, Zou SS, Zhu ZJ, Zhang F, Li Z. Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese. Journal of Assisted Reproduction and Genetics. PMID 27233649 DOI: 10.1007/S10815-016-0738-9  0.357
2016 Stoddard TJ, Clasen BM, Baltes NJ, Demorest ZL, Voytas DF, Zhang F, Luo S. Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA. Plos One. 11: e0154634. PMID 27176769 DOI: 10.1371/Journal.Pone.0154634  0.334
2016 Liu D, Zhang Y, Wang Y, Chen C, Li X, Zhou J, Song Z, Xiao B, Rasco K, Zhang F, Wen S, Li G. Novel Locus for Paroxysmal Kinesigenic Dyskinesia Mapped to Chromosome 3q28-29. Scientific Reports. 6: 25790. PMID 27173777 DOI: 10.1038/srep25790  0.306
2016 Guo S, Li Y, Wang Y, Chu H, Chen Y, Liu Q, Guo G, Tu W, Wu W, Zou H, Yang L, Xiao R, Ma Y, Zhang F, Xiong M, et al. Copy Number Variation of HLA-DQA1 and APOBEC3A/3B Contribute to the Susceptibility of Systemic Sclerosis in the Chinese Han Population. The Journal of Rheumatology. PMID 27036383 DOI: 10.3899/Jrheum.150945  0.436
2016 Hu L, Shang X, Yi S, Cai R, Li Z, Liu C, Liang Y, Cai D, Zhang F, Xu X. Two novel copy number variations involving the α-globin gene cluster on chromosome 16 cause thalassemia in two Chinese families. Molecular Genetics and Genomics : Mgg. PMID 27000657 DOI: 10.1007/S00438-016-1193-0  0.31
2016 Liu Z, Li X, Zhang JT, Cai YJ, Cheng TL, Cheng C, Wang Y, Zhang CC, Nie YH, Chen ZF, Bian WJ, Zhang L, Xiao J, Lu B, Zhang YF, ... ... Zhang F, et al. Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature. PMID 26808898 DOI: 10.1038/Nature16533  0.324
2016 Yan H, Ji H, Yang X, Wu Y, Yang Y, Yu Y, Fan Y, Zhang L, Cao B, Xiao J, Zhang F, Jiang Y, Wang J. Clinical and genetic analysis of idiopathic intellectual disability/development delay Chinese Journal of Applied Clinical Pediatrics. 31: 1475-1479. DOI: 10.3760/Cma.J.Issn.2095-428X.2016.19.010  0.335
2016 Tabebordbar M, Zhu K, Cheng J, Widrick J, Yan W, Xiao R, Vandenberghe L, Zhang F, Wagers A. 483. In Vivo DMD Gene Editing in Muscles and Muscle Stem Cells of Dystrophic Mice Molecular Therapy. 24: S191-S192. DOI: 10.1016/S1525-0016(16)33292-0  0.314
2016 Nelson C, Gemberling M, Hakim CH, Ousterout DG, Thakore PI, Castellanos RM, Madhavan S, Pan X, Ran FA, Yan W, Asokan A, Zhang F, Duan D, Gersbach CA. 482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 24: S191. DOI: 10.1016/S1525-0016(16)33291-9  0.32
2015 Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science (New York, N.Y.). PMID 26721684 DOI: 10.1126/Science.Aad5143  0.353
2015 Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes MS, Wang D, Barak B, Zeng M, Li C, Lu C, Wells M, Amaya A, Nguyen S, Lewis M, Sanjana N, ... ... Zhang F, et al. Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. Neuron. PMID 26687841 DOI: 10.1016/J.Neuron.2015.11.023  0.327
2015 Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science (New York, N.Y.). PMID 26628643 DOI: 10.1126/Science.Aad5227  0.327
2015 Wen Y, Wang W, Guo X, Zhang F. PAPA: a flexible tool for identifying pleiotropic pathways using genome-wide association study summaries. Bioinformatics (Oxford, England). PMID 26568630 DOI: 10.1093/Bioinformatics/Btv668  0.331
2015 Wen Y, Guo X, Hao J, Xiao X, Wang W, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. Integrative analysis of genome-wide association studies and gene expression profiles identified candidate genes for osteoporosis in Kashin-Beck disease patients. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 26462493 DOI: 10.1007/S00198-015-3364-Y  0.342
2015 Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. PMID 26422227 DOI: 10.1016/J.Cell.2015.09.038  0.3
2015 Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, ... ... Zhang F, et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. PMID 26375006 DOI: 10.1038/Nature15521  0.36
2015 Ding J, Zhao D, Du R, Zhang Y, Yang H, Liu J, Yan C, Zhang F, Xiong H. Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy. Brain & Development. PMID 26304763 DOI: 10.1016/J.Braindev.2015.08.005  0.342
2015 Zhang F, Dai L, Lin W, Wang W, Liu X, Zhang J, Yang T, Liu X, Shen H, Chen X, Tan L, Tian Q, Deng HW, Xu X, Guo X. Exome sequencing identified FGF12 as a novel candidate gene for Kashin-Beck disease. Functional & Integrative Genomics. PMID 26290467 DOI: 10.1007/S10142-015-0462-Z  0.398
2015 Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, ... Zhang F, et al. A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks. Cell. PMID 26189680 DOI: 10.1016/J.Cell.2015.06.059  0.31
2015 Wen Y, Hao J, Guo X, Xiao X, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. SWGDT: A sliding window-based genotype dependence testing tool for genome-wide susceptibility gene scan. Journal of Biomedical Informatics. PMID 26188273 DOI: 10.1016/J.Jbi.2015.06.025  0.377
2015 Zhang F. CRISPR-Cas9: Prospects and Challenges. Human Gene Therapy. 26: 409-10. PMID 26176430 DOI: 10.1089/Hum.2015.29002.Fzh  0.388
2015 Zhang F, Lupski JR. Non-coding genetic variants in human disease. Human Molecular Genetics. PMID 26152199 DOI: 10.1093/Hmg/Ddv259  0.486
2015 Sun LY, Zhang YB, Jiang L, Wan N, Wu WF, Pan XD, Yu J, Zhang F, Wang LY. Identification of the gene defect responsible for severe hypercholesterolaemia using whole-exome sequencing. Scientific Reports. 5: 11380. PMID 26077743 DOI: 10.1038/Srep11380  0.328
2015 Luo S, Li J, Stoddard TJ, Baltes NJ, Demorest ZL, Clasen BM, Coffman A, Retterath A, Mathis L, Voytas DF, Zhang F. Non-transgenic plant genome editing using purified sequence-specific nucleases. Molecular Plant. PMID 26074033 DOI: 10.1016/J.Molp.2015.05.012  0.318
2015 Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Sequence determinants of improved CRISPR sgRNA design. Genome Research. PMID 26063738 DOI: 10.1101/Gr.191452.115  0.346
2015 Wang X, Ning Y, Zhang F, Yu F, Tan W, Lei Y, Wu C, Zheng J, Wang S, Yu H, Li Z, Lammi MJ, Guo X. Gene expression signature in endemic osteoarthritis by microarray analysis. International Journal of Molecular Sciences. 16: 11465-81. PMID 25997002 DOI: 10.3390/Ijms160511465  0.317
2015 Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, ... ... Zhang F, et al. Brains, genes, and primates. Neuron. 86: 617-31. PMID 25950631 DOI: 10.1016/J.Neuron.2015.03.021  0.324
2015 Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, et al. Genome editing technologies: defining a path to clinic. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 796-806. PMID 25943494 DOI: 10.1038/Mt.2015.54  0.34
2015 English AC, Salerno WJ, Hampton OA, Gonzaga-Jauregui C, Ambreth S, Ritter DI, Beck CR, Davis CF, Dahdouli M, Ma S, Carroll A, Veeraraghavan N, Bruestle J, Drees B, Hastie A, ... Zhang F, et al. Assessing structural variation in a personal genome-towards a human reference diploid genome. Bmc Genomics. 16: 286. PMID 25886820 DOI: 10.1186/S12864-015-1479-3  0.705
2015 Shalem O, Sanjana NE, Zhang F. High-throughput functional genomics using CRISPR-Cas9. Nature Reviews. Genetics. 16: 299-311. PMID 25854182 DOI: 10.1038/Nrg3899  0.335
2015 Clasen BM, Stoddard TJ, Luo S, Demorest ZL, Li J, Cedrone F, Tibebu R, Davison S, Ray EE, Daulhac A, Coffman A, Yabandith A, Retterath A, Haun W, Baltes NJ, ... ... Zhang F, et al. Improving cold storage and processing traits in potato through targeted gene knockout. Plant Biotechnology Journal. PMID 25846201 DOI: 10.1111/Pbi.12370  0.305
2015 Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/Nature14299  0.34
2015 Zhang H, Dai L, Chen N, Zang L, Leng X, Du L, Wang J, Jiang Y, Zhang F, Wu X, Wu Y. Fifteen novel EIF2B1-5 mutations identified in Chinese children with leukoencephalopathy with vanishing white matter and a long term follow-up. Plos One. 10: e0118001. PMID 25761052 DOI: 10.1371/Journal.Pone.0118001  0.321
2015 Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/J.Cell.2015.02.038  0.324
2015 Cox DB, Platt RJ, Zhang F. Therapeutic genome editing: prospects and challenges. Nature Medicine. 21: 121-31. PMID 25654603 DOI: 10.1038/Nm.3793  0.352
2015 Zhang F, Xiao X, Hao J, Wang S, Wen Y, Guo X. CPAS: a trans-omics pathway analysis tool for jointly analyzing DNA copy number variations and mRNA expression profiles data. Journal of Biomedical Informatics. 53: 363-6. PMID 25546614 DOI: 10.1016/J.Jbi.2014.12.012  0.329
2015 Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 517: 583-8. PMID 25494202 DOI: 10.1038/Nature14136  0.334
2015 Cong L, Zhang F. Genome engineering using CRISPR-Cas9 system. Methods in Molecular Biology (Clifton, N.J.). 1239: 197-217. PMID 25408407 DOI: 10.1007/978-1-4939-1862-1_10  0.322
2015 Chen L, Zhou W, Zhang C, Lupski JR, Jin L, Zhang F. CNV instability associated with DNA replication dynamics: evidence for replicative mechanisms in CNV mutagenesis. Human Molecular Genetics. 24: 1574-83. PMID 25398944 DOI: 10.1093/Hmg/Ddu572  0.543
2015 Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, Sur M, Zhang F. In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nature Biotechnology. 33: 102-6. PMID 25326897 DOI: 10.1038/Nbt.3055  0.372
2015 Peng Z, Zhou W, Fu W, Du R, Jin L, Zhang F. Correlation between frequency of non-allelic homologous recombination and homology properties: evidence from homology-mediated CNV mutations in the human genome. Human Molecular Genetics. 24: 1225-33. PMID 25324539 DOI: 10.1093/Hmg/Ddu533  0.534
2015 Zhang F, Wen Y, Guo X, Zhang Y, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW. Genome-wide pathway-based association study implicates complement system in the development of Kashin-Beck disease in Han Chinese. Bone. 71: 36-41. PMID 25305519 DOI: 10.1016/J.Bone.2014.09.025  0.328
2015 Zhang F, Wen Y, Guo X, Zhang Y, Wang X, Yang T, Shen H, Chen X, Tian Q, Deng HW. Genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in Han Chinese. Arthritis & Rheumatology (Hoboken, N.J.). 67: 176-81. PMID 25303641 DOI: 10.1002/Art.38898  0.355
2015 Bauer DE, Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, ... ... Zhang F, et al. Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing) Blood. 126: 638-638. DOI: 10.1182/Blood.V126.23.638.638  0.401
2015 Nelson CE, Moreb DGOJNREA, Castellanos RM, Ran FA, Yan W, Zhang F, Asokan A, Gersbach CA. 397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34006-0  0.394
2014 Chen L, Zhou W, Zhang L, Zhang F. Genome architecture and its roles in human copy number variation. Genomics & Informatics. 12: 136-44. PMID 25705150 DOI: 10.5808/Gi.2014.12.4.136  0.363
2014 Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. Genome Biology. 15: 554. PMID 25476604 DOI: 10.1186/S13059-014-0554-4  0.349
2014 Zhang F, Wen Y, Guo X, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW. Trans-omics pathway analysis suggests that eQTLs contribute to chondrocyte apoptosis of Kashin-Beck disease through regulating apoptosis pathway expression. Gene. 553: 166-9. PMID 25307768 DOI: 10.1016/J.Gene.2014.10.018  0.315
2014 Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, ... ... Zhang F, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55. PMID 25263330 DOI: 10.1016/J.Cell.2014.09.014  0.362
2014 Chen C, Ma H, Zhang F, Chen L, Xing X, Wang S, Zhang X, Luo Y. Screening of Duchenne muscular dystrophy (DMD) mutations and investigating its mutational mechanism in Chinese patients. Plos One. 9: e108038. PMID 25244321 DOI: 10.1371/Journal.Pone.0108038  0.364
2014 Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 514: 380-4. PMID 25119044 DOI: 10.1038/Nature13589  0.354
2014 Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC. Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. Nature Methods. 11: 915-8. PMID 25108687 DOI: 10.1038/Nmeth.3063  0.318
2014 Sanjana NE, Shalem O, Zhang F. Improved vectors and genome-wide libraries for CRISPR screening. Nature Methods. 11: 783-784. PMID 25075903 DOI: 10.1038/Nmeth.3047  0.309
2014 Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157: 1262-78. PMID 24906146 DOI: 10.1016/J.Cell.2014.05.010  0.339
2014 Song X, Guo S, Chen Y, Yang C, Ji H, Zhang F, Jiang Z, Ma Y, Li Y, Jin L, Zou H, Zhou X, Wang J. Association between HLA-DQA1 gene copy number polymorphisms and susceptibility to rheumatoid arthritis in Chinese Han population. Journal of Genetics. 93: 215-8. PMID 24840843 DOI: 10.1007/S12041-014-0339-2  0.411
2014 Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889  0.307
2014 Xiao J, Zhang L, Wang J, Jiang Y, Jin L, Lu J, Jin L, Zhong C, Xu X, Zhang F. Rearrangement structure-independent strategy of CNV breakpoint analysis. Molecular Genetics and Genomics : Mgg. 289: 755-63. PMID 24737421 DOI: 10.1007/S00438-014-0850-4  0.495
2014 Zhang F, Wen Y, Guo X. CRISPR/Cas9 for genome editing: progress, implications and challenges. Human Molecular Genetics. 23: R40-6. PMID 24651067 DOI: 10.1093/Hmg/Ddu125  0.33
2014 Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, ... ... Zhang F, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (New York, N.Y.). 343: 1246980. PMID 24604203 DOI: 10.1126/Science.1246980  0.336
2014 Zhang X, Du R, Li S, Zhang F, Jin L, Wang H. Evaluation of copy number variation detection for a SNP array platform. Bmc Bioinformatics. 15: 50. PMID 24555668 DOI: 10.1186/1471-2105-15-50  0.393
2014 Liu P, Gelowani V, Zhang F, Drory VE, Ben-Shachar S, Roney E, Medeiros AC, Moore RJ, DiVincenzo C, Burnette WB, Higgins JJ, Li J, Orr-Urtreger A, Lupski JR. Mechanism, prevalence, and more severe neuropathy phenotype of the Charcot-Marie-Tooth type 1A triplication. American Journal of Human Genetics. 94: 462-9. PMID 24530202 DOI: 10.1016/J.Ajhg.2014.01.017  0.532
2014 Chen Y, Guo L, Chen J, Zhao X, Zhou W, Zhang C, Wang J, Jin L, Pei D, Zhang F. Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity. Bmc Genomics. 15: 79. PMID 24472662 DOI: 10.1186/1471-2164-15-79  0.475
2014 Zhang F, Guo X, Zhang Y, Wen Y, Wang W, Wang S, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW. Genome-wide copy number variation study and gene expression analysis identify ABI3BP as a susceptibility gene for Kashin-Beck disease. Human Genetics. 133: 793-9. PMID 24442417 DOI: 10.1007/S00439-014-1418-4  0.365
2014 Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, Zhang F, Chapman K, Lupski JR, Noebels JL, Goldman AM. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 55: e6-12. PMID 24372310 DOI: 10.1111/Epi.12489  0.489
2014 Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.). 343: 84-7. PMID 24336571 DOI: 10.1126/Science.1247005  0.348
2014 Wu SX, Wang WZ, Zhang F, Wu CY, Dennis BS, Qu CJ, Bai YD, Guo X. Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis. Gene. 535: 124-30. PMID 24316489 DOI: 10.1016/J.Gene.2013.11.050  0.314
2014 Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, ... ... Zhang F, et al. Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Human Molecular Genetics. 23: 1923-33. PMID 24249740 DOI: 10.1093/Hmg/Ddt575  0.318
2014 Qi Y, Starker CG, Zhang F, Baltes NJ, Voytas DF. Tailor-made mutations in Arabidopsis using zinc finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 1062: 193-209. PMID 24057367 DOI: 10.1007/978-1-62703-580-4_10  0.332
2014 Zhang H, Wu Y, Chen N, Dai L, Zang L, Leng X, Du L, Wang J, Jiang Y, Zhang F. Genotypic features of EIF2B1-5 in Chinese patients with vanishing white matter disease Chinese Journal of Applied Clinical Pediatrics. 29: 52-56. DOI: 10.3760/Cma.J.Issn.2095-428X.2014.01.015  0.318
2014 Sheffer M, Hu Y, Shalem O, Sanjana N, Dhimolea E, Sarkar S, Bariteau MA, Aftab BT, Groen RWJ, Zhang F, Mitsiades CS. Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition Blood. 124: 273-273. DOI: 10.1182/Blood.V124.21.273.273  0.338
2014 Wu S, Duan C, Zhang F, McKenzie RP, Zheng J, Farooq U, Bai Y, Guo X. Difference in apoptosis-associated genes expression profiling and immunohistology analysis between Kashin-Beck disease and primary osteoarthritis Chinese Science Bulletin. 59: 833-839. DOI: 10.1007/S11434-014-0130-Z  0.301
2013 Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nature Protocols. 8: 2281-308. PMID 24157548 DOI: 10.1038/Nprot.2013.143  0.31
2013 Jia X, Zhang F, Bai J, Gao L, Zhang X, Sun H, Sun D, Guan R, Sun W, Xu L, Yue Z, Yu Y, Fu S. Combinational analysis of linkage and exome sequencing identifies the causative mutation in a Chinese family with congenital cataract. Bmc Medical Genetics. 14: 107. PMID 24103489 DOI: 10.1186/1471-2350-14-107  0.362
2013 Wang J, Yang Y, Guo S, Chen Y, Yang C, Ji H, Song X, Zhang F, Jiang Z, Ma Y, Li Y, Du A, Jin L, Reveille JD, Zou H, et al. Association between copy number variations of HLA-DQA1 and ankylosing spondylitis in the Chinese Han population Genes and Immunity. 14: 500-503. PMID 24048351 DOI: 10.1038/Gene.2013.46  0.472
2013 Zhang F, Liang J, Guo X, Zhang Y, Wen Y, Li Q, Zhang Z, Ma W, Dai L, Liu X, Yang L, Wang J. Exome sequencing and functional analysis identifies a novel mutation in EXT1 gene that causes multiple osteochondromas. Plos One. 8: e72316. PMID 24009674 DOI: 10.1371/Journal.Pone.0072316  0.377
2013 Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154: 1380-9. PMID 23992846 DOI: 10.1016/J.Cell.2013.08.021  0.316
2013 Qi Y, Li X, Zhang Y, Starker CG, Baltes NJ, Zhang F, Sander JD, Reyon D, Joung JK, Voytas DF. Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases. G3 (Bethesda, Md.). 3: 1707-15. PMID 23979943 DOI: 10.1534/G3.113.006270  0.334
2013 He SL, Tan WH, Zhang ZT, Zhang F, Qu CJ, Lei YX, Zhu YH, Yu HJ, Xiang YZ, Guo X. Mitochondrial-related gene expression profiles suggest an important role of PGC-1alpha in the compensatory mechanism of endemic dilated cardiomyopathy. Experimental Cell Research. 319: 2604-16. PMID 23954821 DOI: 10.1016/J.Yexcr.2013.07.018  0.311
2013 Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/Nature12466  0.345
2013 Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nature Biotechnology. 31: 827-32. PMID 23873081 DOI: 10.1038/Nbt.2647  0.306
2013 Lu C, Wang Y, Zhang F, Lu F, Xu M, Qin Y, Wu W, Li S, Song L, Yang S, Wu D, Jin L, Shen H, Sha J, Xia Y, et al. DAZ duplications confer the predisposition of Y chromosome haplogroup K* to non-obstructive azoospermia in Han Chinese populations. Human Reproduction (Oxford, England). 28: 2440-9. PMID 23696539 DOI: 10.1093/Humrep/Det234  0.439
2013 Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 153: 910-8. PMID 23643243 DOI: 10.1016/J.Cell.2013.04.025  0.359
2013 Zhao Y, Han Y, Zhang L, Wang Y, Ma Y, Zhang F, Fu D, Wang X. Quantitative assessment of the effect of cytochrome P450 2C9 gene polymorphism and colorectal cancer. Plos One. 8: e60607. PMID 23577132 DOI: 10.1371/Journal.Pone.0060607  0.327
2013 Zhou W, Zhang F, Chen X, Shen Y, Lupski JR, Jin L. Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms. Human Molecular Genetics. 22: 2642-51. PMID 23474816 DOI: 10.1093/Hmg/Ddt113  0.595
2013 Chen X, Shen Y, Zhang F, Chiang C, Pillalamarri V, Blumenthal I, Talkowski M, Wu BL, Gusella JF. Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs. American Journal of Human Genetics. 92: 375-86. PMID 23472757 DOI: 10.1016/J.Ajhg.2013.02.006  0.33
2013 Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nature Biotechnology. 31: 233-9. PMID 23360965 DOI: 10.1038/Nbt.2508  0.332
2013 Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.). 339: 819-23. PMID 23287718 DOI: 10.1126/Science.1231143  0.32
2013 Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF. Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. Genome Research. 23: 547-54. PMID 23282329 DOI: 10.1101/Gr.145557.112  0.332
2013 Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, ... ... Zhang F, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 12: 238-51. PMID 23246482 DOI: 10.1016/J.Stem.2012.11.011  0.325
2013 Sun Z, Liu P, Jia X, Withers MA, Jin L, Lupski JR, Zhang F. Replicative mechanisms of CNV formation preferentially occur as intrachromosomal events: evidence from Potocki-Lupski duplication syndrome. Human Molecular Genetics. 22: 749-56. PMID 23161748 DOI: 10.1093/Hmg/Dds482  0.612
2013 Zhang F, Guo X, Duan C, Wu S, Yu H, Lammi M. Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin-Beck disease). Scandinavian Journal of Rheumatology. 42: 71-9. PMID 23157206 DOI: 10.3109/03009742.2012.698303  0.303
2013 Zhang Y, Zhang F, Li X, Baller JA, Qi Y, Starker CG, Bogdanove AJ, Voytas DF. Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiology. 161: 20-7. PMID 23124327 DOI: 10.1104/Pp.112.205179  0.33
2013 Zhang P, Gao Z, Jiang Y, Wang J, Zhang F, Wang S, Yang Y, Xiong H, Zhang Y, Bao X, Xiao J, Wu X, Wu Y. Follow‐up study of 25 Chinese children with PLA2G6‐associated neurodegeneration European Journal of Neurology. 20: 322-330. PMID 22934738 DOI: 10.1111/J.1468-1331.2012.03856.X  0.312
2012 Zhang F, Guo X, Wu S, Han J, Liu Y, Shen H, Deng HW. Genome-wide pathway association studies of multiple correlated quantitative phenotypes using principle component analyses. Plos One. 7: e53320. PMID 23285279 DOI: 10.1371/Journal.Pone.0053320  0.351
2012 Zhang YP, Deng FY, Yang TL, Zhang F, Chen XD, Shen H, Zhu XZ, Tian Q, Deng HW. Genome-wide association study identified CNP12587 region underlying height variation in Chinese females. Plos One. 7: e44292. PMID 22957059 DOI: 10.1371/Journal.Pone.0044292  0.392
2012 Hsu PD, Zhang F. Dissecting neural function using targeted genome engineering technologies. Acs Chemical Neuroscience. 3: 603-610. PMID 22896804 DOI: 10.1021/Cn300089K  0.304
2012 Zhang F, Guo X, Wang W, Wu S, Ma W, Yan H. Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy Kashin-Beck Disease. Bmc Musculoskeletal Disorders. 13: 130. PMID 22828367 DOI: 10.1186/1471-2474-13-130  0.331
2012 Du R, Lu C, Jiang Z, Li S, Ma R, An H, Xu M, An Y, Xia Y, Jin L, Wang X, Zhang F. Efficient typing of copy number variations in a segmental duplication-mediated rearrangement hotspot using multiplex competitive amplification. Journal of Human Genetics. 57: 545-51. PMID 22673690 DOI: 10.1038/Jhg.2012.66  0.391
2012 Ning Y, Zhang F, Zhu Y, Chen H, Lu J, Li Z. Novel androgen receptor gene mutation in patient with complete androgen insensitivity syndrome. Urology. 80: 216-218. PMID 22608796 DOI: 10.1016/J.Urology.2012.03.028  0.342
2012 Jiang Y, Zhang Y, Zhang P, Sang T, Zhang F, Ji T, Huang Q, Xie H, Du R, Cai B, Zhao H, Wang J, Wu Y, Wu H, Xu K, et al. NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy. Human Genetics. 131: 1217-24. PMID 22367439 DOI: 10.1007/S00439-012-1149-3  0.341
2012 Zhang LS, Hu HG, Liu YJ, Li J, Yu P, Zhang F, Yang TL, Tian Q, Zheng YP, Guo Y, Deng HW. A follow-up association study of two genetic variants for bone mineral density variation in Caucasians. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 23: 1867-75. PMID 22159821 DOI: 10.1007/S00198-011-1863-Z  0.309
2011 Liu P, Lacaria M, Zhang F, Withers M, Hastings PJ, Lupski JR. Frequency of nonallelic homologous recombination is correlated with length of homology: evidence that ectopic synapsis precedes ectopic crossing-over. American Journal of Human Genetics. 89: 580-8. PMID 21981782 DOI: 10.1016/J.Ajhg.2011.09.009  0.521
2011 Liu P, Erez A, Nagamani SC, Dhar SU, Kołodziejska KE, Dharmadhikari AV, Cooper ML, Wiszniewska J, Zhang F, Withers MA, Bacino CA, Campos-Acevedo LD, Delgado MR, Freedenberg D, Garnica A, et al. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell. 146: 889-903. PMID 21925314 DOI: 10.1016/J.Cell.2011.07.042  0.488
2011 Lu C, Zhang F, Yang H, Xu M, Du G, Wu W, An Y, Qin Y, Ji G, Han X, Gu A, Xia Y, Song L, Wang S, Jin L, et al. Additional genomic duplications in AZFc underlie the b2/b3 deletion-associated risk of spermatogenic impairment in Han Chinese population. Human Molecular Genetics. 20: 4411-21. PMID 21852246 DOI: 10.1093/Hmg/Ddr369  0.498
2011 Hancock CN, Zhang F, Floyd K, Richardson AO, Lafayette P, Tucker D, Wessler SR, Parrott WA. The rice miniature inverted repeat transposable element mPing is an effective insertional mutagen in soybean. Plant Physiology. 157: 552-62. PMID 21844309 DOI: 10.1104/Pp.111.181206  0.329
2011 Du R, Jin L, Zhang F. [Copy number variations in the human genome: their mutational mechanisms and roles in diseases]. Hereditas. 33: 857-869. PMID 21831802 DOI: 10.3724/Sp.J.1005.2011.00857  0.43
2011 Zhang F, Guo X, Wang W, Yan H, Li C. Genome-wide gene expression analysis suggests an important role of hypoxia in the pathogenesis of endemic osteochondropathy Kashin-Beck disease. Plos One. 6: e22983. PMID 21829570 DOI: 10.1371/Journal.Pone.0022983  0.349
2011 Boone PM, Liu P, Zhang F, Carvalho CM, Towne CF, Batish SD, Lupski JR. Alu-specific microhomology-mediated deletion of the final exon of SPAST in three unrelated subjects with hereditary spastic paraplegia. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 13: 582-92. PMID 21659953 DOI: 10.1097/Gim.0B013E3182106775  0.535
2011 Zhu H, Shang D, Sun M, Choi S, Liu Q, Hao J, Figuera LE, Zhang F, Choy KW, Ao Y, Liu Y, Zhang XL, Yue F, Wang MR, Jin L, et al. X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3. American Journal of Human Genetics. 88: 819-26. PMID 21636067 DOI: 10.1016/J.Ajhg.2011.05.004  0.499
2011 Curtin SJ, Zhang F, Sander JD, Haun WJ, Starker C, Baltes NJ, Reyon D, Dahlborg EJ, Goodwin MJ, Coffman AP, Dobbs D, Joung JK, Voytas DF, Stupar RM. Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiology. 156: 466-73. PMID 21464476 DOI: 10.1104/Pp.111.172981  0.353
2011 Zhang F, Guo X, Deng H. Multilocus association testing of quantitative traits based on partial least-squares analysis. Plos One. 6. PMID 21304821 DOI: 10.1371/Journal.Pone.0016739  0.341
2011 Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR. ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. Bmc Genomics. 12: 83. PMID 21276248 DOI: 10.1186/1471-2164-12-83  0.305
2011 Carvalho CM, Zhang F, Lupski JR. Structural variation of the human genome: mechanisms, assays, and role in male infertility. Systems Biology in Reproductive Medicine. 57: 3-16. PMID 21210740 DOI: 10.3109/19396368.2010.527427  0.532
2011 Zhang F, Voytas DF. Targeted mutagenesis in Arabidopsis using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 701: 167-77. PMID 21181530 DOI: 10.1007/978-1-61737-957-4_9  0.328
2011 Soler-Alfonso C, Motil KJ, Turk CL, Robbins-Furman P, Friedman EM, Zhang F, Lupski JR, Fraley JK, Potocki L. Potocki-Lupski syndrome: a microduplication syndrome associated with oropharyngeal dysphagia and failure to thrive. The Journal of Pediatrics. 158: 655-659.e2. PMID 21168152 DOI: 10.1016/J.Jpeds.2010.09.062  0.415
2010 Tan L, Liu R, Lei S, Pan R, Yang T, Yan H, Pei Y, Yang F, Zhang F, Pan F, Zhang Y, Hu H, Levy S, Deng H. A genome-wide association analysis implicates SOX6 as a candidate gene for wrist bone mass. Science China. Life Sciences. 53: 1065-72. PMID 21104366 DOI: 10.1007/S11427-010-4056-7  0.311
2010 Fu W, Zhang F, Wang Y, Gu X, Jin L. Identification of copy number variation hotspots in human populations. American Journal of Human Genetics. 87: 494-504. PMID 20920665 DOI: 10.1016/J.Ajhg.2010.09.006  0.549
2010 El-Hattab AW, Zhang F, Maxim R, Christensen KM, Ward JC, Hines-Dowell S, Scaglia F, Lupski JR, Cheung SW. Deletion and duplication of 15q24: molecular mechanisms and potential modification by additional copy number variants. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 12: 573-86. PMID 20860070 DOI: 10.1097/Gim.0B013E3181Eb9B4A  0.452
2010 Hoshaw JP, Unger-Wallace E, Zhang F, Voytas DF. A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets. Methods in Molecular Biology (Clifton, N.J.). 649: 299-313. PMID 20680843 DOI: 10.1007/978-1-60761-753-2_19  0.313
2010 Gonzaga-Jauregui C, Zhang F, Towne CF, Batish SD, Lupski JR. GJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease. Neurogenetics. 11: 465-70. PMID 20532933 DOI: 10.1007/S10048-010-0247-4  0.586
2010 Zhang F, Maeder ML, Unger-Wallace E, Hoshaw JP, Reyon D, Christian M, Li X, Pierick CJ, Dobbs D, Peterson T, Joung JK, Voytas DF. High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 107: 12028-33. PMID 20508152 DOI: 10.1073/Pnas.0914991107  0.336
2010 Zhang F, Seeman P, Liu P, Weterman MA, Gonzaga-Jauregui C, Towne CF, Batish SD, De Vriendt E, De Jonghe P, Rautenstrauss B, Krause KH, Khajavi M, Posadka J, Vandenberghe A, Palau F, et al. Mechanisms for nonrecurrent genomic rearrangements associated with CMT1A or HNPP: rare CNVs as a cause for missing heritability. American Journal of Human Genetics. 86: 892-903. PMID 20493460 DOI: 10.1016/J.Ajhg.2010.05.001  0.555
2010 Hancock CN, Zhang F, Wessler SR. Transposition of the Tourist-MITE mPing in yeast: an assay that retains key features of catalysis by the class 2 PIF/Harbinger superfamily. Mobile Dna. 1: 5. PMID 20226077 DOI: 10.1186/1759-8753-1-5  0.302
2010 Lupski JR, Reid JG, Gonzaga-Jauregui C, Rio Deiros D, Chen DC, Nazareth L, Bainbridge M, Dinh H, Jing C, Wheeler DA, McGuire AL, Zhang F, Stankiewicz P, Halperin JJ, Yang C, et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. The New England Journal of Medicine. 362: 1181-91. PMID 20220177 DOI: 10.1056/Nejmoa0908094  0.563
2010 Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, Yan H, Pei YF, Zhang F, Papasian CJ, Recker RR, et al. Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1572-80. PMID 20200951 DOI: 10.1002/Jbmr.36  0.33
2010 Zhang F, Potocki L, Sampson JB, Liu P, Sanchez-Valle A, Robbins-Furman P, Navarro AD, Wheeler PG, Spence JE, Brasington CK, Withers MA, Lupski JR. Identification of uncommon recurrent Potocki-Lupski syndrome-associated duplications and the distribution of rearrangement types and mechanisms in PTLS. American Journal of Human Genetics. 86: 462-70. PMID 20188345 DOI: 10.1016/J.Ajhg.2010.02.001  0.561
2010 Carvalho CM, Zhang F, Lupski JR. Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 1765-71. PMID 20080665 DOI: 10.1073/Pnas.0906222107  0.536
2010 Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, et al. Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. Plos Genetics. 6: e1000806. PMID 20072603 DOI: 10.1371/Journal.Pgen.1000806  0.34
2009 Ramocki MB, Peters SU, Tavyev YJ, Zhang F, Carvalho CM, Schaaf CP, Richman R, Fang P, Glaze DG, Lupski JR, Zoghbi HY. Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome. Annals of Neurology. 66: 771-82. PMID 20035514 DOI: 10.1002/Ana.21715  0.53
2009 Naito K, Zhang F, Tsukiyama T, Saito H, Hancock CN, Richardson AO, Okumoto Y, Tanisaka T, Wessler SR. Unexpected consequences of a sudden and massive transposon amplification on rice gene expression. Nature. 461: 1130-4. PMID 19847266 DOI: 10.1038/Nature08479  0.357
2009 Zhang F, Gu W, Hurles ME, Lupski JR. Copy number variation in human health, disease, and evolution. Annual Review of Genomics and Human Genetics. 10: 451-481. PMID 19715442 DOI: 10.1146/Annurev.Genom.9.081307.164217  0.562
2009 Nagamani SC, Zhang F, Shchelochkov OA, Bi W, Ou Z, Scaglia F, Probst FJ, Shinawi M, Eng C, Hunter JV, Sparagana S, Lagoe E, Fong CT, Pearson M, Doco-Fenzy M, et al. Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment. Journal of Medical Genetics. 46: 825-33. PMID 19584063 DOI: 10.1136/Jmg.2009.067637  0.537
2009 Zhang F, Carvalho CMB, Lupski JR. Complex human chromosomal and genomic rearrangements Trends in Genetics. 25: 298-307. PMID 19560228 DOI: 10.1016/J.Tig.2009.05.005  0.513
2009 Zhang F, Khajavi M, Connolly AM, Towne CF, Batish SD, Lupski JR. The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans. Nature Genetics. 41: 849-53. PMID 19543269 DOI: 10.1038/Ng.399  0.518
2009 Carvalho CM, Zhang F, Liu P, Patel A, Sahoo T, Bacino CA, Shaw C, Peacock S, Pursley A, Tavyev YJ, Ramocki MB, Nawara M, Obersztyn E, Vianna-Morgante AM, Stankiewicz P, et al. Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching. Human Molecular Genetics. 18: 2188-203. PMID 19324899 DOI: 10.1093/Hmg/Ddp151  0.514
2009 Lin R, Wang X, Wang Y, Zhang F, Wang Y, Fu W, Yu T, Li S, Xiong M, Huang W, Jin L. Association of polymorphisms in four bilirubin metabolism genes with serum bilirubin in three Asian populations. Human Mutation. 30: 609-15. PMID 19243019 DOI: 10.1002/Humu.20895  0.431
2009 Bi W, Sapir T, Shchelochkov OA, Zhang F, Withers MA, Hunter JV, Levy T, Shinder V, Peiffer DA, Gunderson KL, Nezarati MM, Shotts VA, Amato SS, Savage SK, Harris DJ, et al. Increased LIS1 expression affects human and mouse brain development. Nature Genetics. 41: 168-77. PMID 19136950 DOI: 10.1038/Ng.302  0.495
2009 Lu C, Zhang J, Li Y, Xia Y, Zhang F, Wu B, Wu W, Ji G, Gu A, Wang S, Jin L, Wang X. The b2/b3 subdeletion shows higher risk of spermatogenic failure and higher frequency of complete AZFc deletion than the gr/gr subdeletion in a Chinese population Human Molecular Genetics. 18: 1122-1130. PMID 19088127 DOI: 10.1093/Hmg/Ddn427  0.423
2009 Yan J, Zhang F, Brundage E, Scheuerle A, Lanpher B, Erickson RP, Powis Z, Robinson HB, Trapane PL, Stachiw-Hietpas D, Keppler-Noreuil KM, Lalani SR, Sahoo T, Chinault AC, Patel A, et al. Genomic duplication resulting in increased copy number of genes encoding the sister chromatid cohesion complex conveys clinical consequences distinct from Cornelia de Lange. Journal of Medical Genetics. 46: 626-34. PMID 19052029 DOI: 10.1136/Jmg.2008.062471  0.583
2008 Zhang ZX, Lei SF, Deng FY, Zhang F, Liu YJ, Recker RR, Papasian CJ, Deng HW. Bivariate genome-wide linkage analysis for traits BMD and AAM: effect of menopause on linkage signals. Maturitas. 62: 16-20. PMID 19019586 DOI: 10.1016/J.Maturitas.2008.10.001  0.324
2008 Gu W, Zhang F, Lupski JR. Mechanisms for human genomic rearrangements Pathogenetics. 1: 4-4. PMID 19014668 DOI: 10.1186/1755-8417-1-4  0.508
2008 Shi H, Zhong H, Peng Y, Dong YL, Qi XB, Zhang F, Liu LF, Tan SJ, Ma RZ, Xiao CJ, Wells RS, Jin L, Su B. Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations. Bmc Biology. 6: 45. PMID 18959782 DOI: 10.1186/1741-7007-6-45  0.411
2008 Doco-Fenzy M, Holder-Espinasse M, Bieth E, Magdelaine C, Vincent M, Khoury M, Andrieux J, Zhang F, Lupski JR, Klink R, Schneider A, Goze-Martineau O, Cuisset J, Vallee L, Manouvrier-Hanu S, et al. The clinical spectrum associated with a chromosome 17 short arm proximal duplication (dup 17p11.2) in three patients. American Journal of Medical Genetics Part A. 146: 917-924. PMID 18327785 DOI: 10.1002/Ajmg.A.32195  0.484
2008 Xue F, Wang Y, Xu S, Zhang F, Wen B, Wu X, Lu M, Deka R, Qian J, Jin L. A spatial analysis of genetic structure of human populations in China reveals distinct difference between maternal and paternal lineages. European Journal of Human Genetics : Ejhg. 16: 705-17. PMID 18212820 DOI: 10.1038/Sj.Ejhg.5201998  0.44
2008 Zhang F, Xiao P, Yang F, Shen H, Xiong DH, Deng HY, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW. A whole genome linkage scan for QTLs underlying peak bone mineral density. Osteoporosis International. 19: 303-310. PMID 17882466 DOI: 10.1007/S00198-007-0468-Z  0.317
2007 He LN, Xiong DH, Liu YJ, Zhang F, Recker RR, Deng HW. Association study of the oestrogen signalling pathway genes in relation to age at natural menopause. Journal of Genetics. 86: 269-276. PMID 18305346 DOI: 10.1007/S12041-007-0034-7  0.331
2007 Zhang Q, Zhang F, Chen XH, Wang YQ, Wang WQ, Lin AA, Cavalli-Sforza LL, Jin L, Huo R, Sha JH, Li Z, Su B. Rapid evolution, genetic variations, and functional association of the human spermatogenesis-related gene NYD-SP12. Journal of Molecular Evolution. 65: 154-61. PMID 17665087 DOI: 10.1007/S00239-006-0127-6  0.47
2007 Yang G, Zhang F, Hancock CN, Wessler SR. Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 104: 10962-7. PMID 17578919 DOI: 10.1073/Pnas.0702080104  0.31
2007 Lu C, Zhang F, Xia Y, Wu B, Gu A, Lu N, Wang S, Shen H, Jin L, Wang X. The association of Y chromosome haplogroups with spermatogenic failure in the Han Chinese. Journal of Human Genetics. 52: 659-663. PMID 17558462 DOI: 10.1007/S10038-007-0160-3  0.481
2007 Chen Y, Xiong DH, Yang TL, Yang F, Jiang H, Zhang F, Shen H, Xiao P, Recker RR, Deng HW. Variations in RANK gene are associated with adult height in Caucasians. American Journal of Human Biology : the Official Journal of the Human Biology Council. 19: 559-65. PMID 17546619 DOI: 10.1002/Ajhb.20619  0.332
2007 Zhang F, Lu C, Li Z, Xie P, Xia Y, Zhu X, Wu B, Cai X, Wang X, Qian J, Wang X, Jin L. Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertility. Journal of Medical Genetics. 44: 437-44. PMID 17412880 DOI: 10.1136/Jmg.2007.049056  0.502
2007 Zhang F, Su B, Zhang Y, Jin L. Genetic studies of human diversity in East Asia Philosophical Transactions of the Royal Society B. 362: 987-996. PMID 17317646 DOI: 10.1098/Rstb.2007.2028  0.482
2006 Zhang J, Zhang F, Peterson T. Transposition of reversed Ac element ends generates novel chimeric genes in maize. Plos Genetics. 2: e164. PMID 17029561 DOI: 10.1371/Journal.Pgen.0020164  0.308
2006 Zhang F, Peterson T. Gene conversion between direct noncoding repeats promotes genetic and phenotypic diversity at a regulatory locus of Zea mays (L.). Genetics. 174: 753-62. PMID 16816430 DOI: 10.1534/Genetics.105.053942  0.357
2006 Zhang F, Li Z, Wen B, Jiang J, Shao M, Zhao Y, He Y, Song X, Qian J, Lu D, Jin L. A frequent partial AZFc deletion does not render an increased risk of spermatogenic impairment in East Asians. Annals of Human Genetics. 70: 304-13. PMID 16674553 DOI: 10.1111/J.1529-8817.2005.00231.X  0.347
2005 Wen B, Li H, Gao S, Mao X, Gao Y, Li F, Zhang F, He Y, Dong Y, Zhang Y, Huang W, Jin J, Xiao C, Lu D, Chakraborty R, et al. Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages. Molecular Biology and Evolution. 22: 725-34. PMID 15548747 DOI: 10.1093/Molbev/Msi055  0.445
2004 Wen B, Li H, Lu D, Song X, Zhang F, He Y, Li F, Gao Y, Mao X, Zhang L, Qian J, Tan J, Jin J, Huang W, Deka R, et al. Genetic evidence supports demic diffusion of Han culture. Nature. 431: 302-5. PMID 15372031 DOI: 10.1038/Nature02878  0.439
Show low-probability matches.