Emily H. Cheng - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology

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Year Citation  Score
2023 Gitego N, Agianian B, Mak OW, Kumar Mv V, Cheng EH, Gavathiotis E. Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature Communications. 14: 8381. PMID 38104127 DOI: 10.1038/s41467-023-44084-3  0.475
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Cheng EH, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.637
2020 Msaouel P, Malouf GG, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, ... ... Cheng EH, et al. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. PMID 32359397 DOI: 10.1016/J.Ccell.2020.04.002  0.32
2019 Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra JG, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka ZP, Casuscelli J, ... ... Cheng EH, et al. Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. Elife. 8. PMID 30924768 DOI: 10.7554/Elife.38986  0.356
2019 Xu J, Reznik E, Lee H, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra J, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka Z, Casuscelli J, ... ... Cheng EH, et al. Author response: Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma Elife. DOI: 10.7554/Elife.38986.025  0.319
2019 Tanaka K, Han S, Ganesan YT, Hsieh JJ, Cheng EH. Abstract 698: Enhancing apoptosis to improve the therapy ofEGFR-mutant lung cancer Cancer Research. 79: 698-698. DOI: 10.1158/1538-7445.Am2019-698  0.353
2018 Dong Y, Eskandari R, Ray C, Granlund KL, Dos Santos-Cunha L, Miloushev VZ, Tee SS, Jeong S, Aras O, Chen YB, Cheng EH, Hsieh JJ, Keshari KR. Hyperpolarized MRI visualizes Warburg effects and predicts treatment response to mTOR inhibitors in patient-derived ccRCC xenograft models. Cancer Research. PMID 30459151 DOI: 10.1158/0008-5472.Can-18-2231  0.328
2018 Hsieh JJ, Le VH, Oyama T, Ricketts CJ, Ho TH, Cheng EH. Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018792549. PMID 30372397 DOI: 10.1200/Jco.2018.79.2549  0.4
2018 Jeng PS, Inoue-Yamauchi A, Hsieh JJ, Cheng EH. BH3-Dependent and Independent Activation of BAX and BAK in Mitochondrial Apoptosis. Current Opinion in Physiology. 3: 71-81. PMID 30334018 DOI: 10.1016/J.Cophys.2018.03.005  0.534
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Cheng EH, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.72
2017 Hsieh JJ, Le V, Cao D, Cheng EH, Creighton CJ. Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision. The Journal of Pathology. PMID 29266437 DOI: 10.1002/Path.5022  0.315
2017 Wang GX, Tu HC, Dong Y, Skanderup AJ, Wang Y, Takeda S, Ganesan YT, Han S, Liu H, Hsieh JJ, Cheng EH. ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival. Cell Reports. 21: 2926-2939. PMID 29212036 DOI: 10.1016/J.Celrep.2017.11.030  0.644
2017 Becerra MF, Reznik E, Redzematovic A, Tennenbaum DM, Kashan M, Ghanaat M, Casuscelli J, Manley B, Jonsson P, DiNatale RG, Blum KA, Durack JC, Solomon SB, Arcila ME, Bourque C, ... ... Cheng EH, et al. Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma. European Urology Focus. PMID 29066084 DOI: 10.1016/J.Euf.2017.09.016  0.304
2017 Nargund AM, Osmanbeyoglu HU, Cheng EH, Hsieh JJ. SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer. Molecular & Cellular Oncology. 4: e1342747. PMID 28868352 DOI: 10.1080/23723556.2017.1342747  0.331
2017 Inoue-Yamauchi A, Jeng PS, Kim K, Chen HC, Han S, Ganesan YT, Ishizawa K, Jebiwott S, Dong Y, Pietanza MC, Hellmann MD, Kris MG, Hsieh JJ, Cheng EH. Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. Nature Communications. 8: 16078. PMID 28714472 DOI: 10.1038/Ncomms16078  0.541
2017 Fujiki Y, Miyata N, Mukai S, Okumoto K, Cheng EH. BAK regulates catalase release from peroxisomes. Molecular & Cellular Oncology. 4: e1306610. PMID 28616584 DOI: 10.1080/23723556.2017.1306610  0.409
2017 Nargund AM, Pham CG, Dong Y, Wang PI, Osmangeyoglu HU, Xie Y, Aras O, Han S, Oyama T, Takeda S, Ray CE, Dong Z, Berge M, Hakimi AA, Monette S, ... ... Cheng EH, et al. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Reports. 18: 2893-2906. PMID 28329682 DOI: 10.1016/J.Celrep.2017.02.074  0.361
2017 Şenbabaoğlu Y, Gejman RS, Winer AG, Liu M, Van Allen EM, de Velasco G, Miao D, Ostrovnaya I, Drill E, Luna A, Weinhold N, Lee W, Manley BJ, Khalil DN, Kaffenberger SD, ... ... Cheng EH, et al. Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biology. 18: 46. PMID 28249590 DOI: 10.1186/S13059-017-1180-8  0.313
2017 Hosoi KI, Miyata N, Mukai S, Furuki S, Okumoto K, Cheng EH, Fujiki Y. The VDAC2-BAK axis regulates peroxisomal membrane permeability. The Journal of Cell Biology. PMID 28174205 DOI: 10.1083/Jcb.201605002  0.419
2016 Dong Y, Manley BJ, Becerra MF, Redzematovic A, Casuscelli J, Tennenbaum DM, Reznik E, Han S, Benfante N, Chen YB, Arcila ME, Aras O, Voss MH, Feldman DR, Motzer RJ, ... ... Cheng EH, et al. Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples. European Urology Focus. PMID 28753786 DOI: 10.1016/J.Euf.2016.08.005  0.351
2016 Şenbabaoğlu Y, Gejman RS, Winer AG, Liu M, Van Allen EM, de Velasco G, Miao D, Ostrovnaya I, Drill E, Luna A, Weinhold N, Lee W, Manley BJ, Khalil DN, Kaffenberger SD, ... ... Cheng EH, et al. Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biology. 17: 231. PMID 27855702 DOI: 10.1186/S13059-016-1092-Z  0.319
2016 Garner TP, Reyna DE, Priyadarshi A, Chen HC, Li S, Wu Y, Ganesan YT, Malashkevich VN, Cheng EH, Gavathiotis E. An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway. Molecular Cell. 64: 431. PMID 27768876 DOI: 10.1016/J.Molcel.2016.10.005  0.393
2016 Hsieh JJ, Cheng EH. A braided cancer river connects tumor heterogeneity and precision medicine. Clinical and Translational Medicine. 5: 42. PMID 27766604 DOI: 10.1186/S40169-016-0123-4  0.31
2016 Chen YB, Xu J, Skanderup AJ, Dong Y, Brannon AR, Wang L, Won HH, Wang PI, Nanjangud GJ, Jungbluth AA, Li W, Ojeda V, Hakimi AA, Voss MH, Schultz N, ... ... Cheng EH, et al. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nature Communications. 7: 13131. PMID 27713405 DOI: 10.1038/Ncomms13131  0.373
2016 Hsieh JJ, Manley B, Khan N, Gao J, Carlo MI, Cheng EH. Overcome Tumor Heterogeneity-Imposed Therapeutic Barriers through Convergent Genomic Biomarker Discovery: A Braided Cancer River Model of Kidney Cancer. Seminars in Cell & Developmental Biology. PMID 27615548 DOI: 10.1016/J.Semcdb.2016.09.002  0.333
2016 Mandal T, Shin S, Aluvila S, Chen HC, Grieve C, Choe JY, Cheng EH, Hustedt EJ, Oh KJ. Assembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic pore. Scientific Reports. 6: 30763. PMID 27488021 DOI: 10.1038/Srep30763  0.348
2016 Xu J, Pham CG, Albanese SK, Dong Y, Oyama T, Lee CH, Rodrik-Outmezguine V, Yao Z, Han S, Chen D, Parton DL, Chodera JD, Rosen N, Cheng EH, Hsieh JJ. Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin. The Journal of Clinical Investigation. PMID 27482884 DOI: 10.1172/Jci86120  0.398
2016 Garner TP, Reyna DE, Priyadarshi A, Chen HC, Li S, Wu Y, Ganesan YT, Malashkevich VN, Almo SS, Cheng EH, Gavathiotis E. An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway. Molecular Cell. PMID 27425408 DOI: 10.1016/J.Molcel.2016.06.010  0.509
2016 Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, ... ... Cheng EH, et al. An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma. Cancer Cell. 29: 104-116. PMID 26766592 DOI: 10.1016/J.Ccell.2015.12.004  0.308
2016 Lee C, Wei E, Lee W, Chen Y, Mano R, Hakimi AA, Dong Y, Redzematovic A, Cross JR, Tickoo S, Srinivasan R, Oschwald D, Reuter VE, Dunphy M, Cheng E, et al. Genomic and metabolic characterization of succinate dehydrogenase B deficient renal cell carcinoma. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E16102  0.304
2016 Inoue-Yamauchi A, Jeng P, Kim K, Chen H, Han S, Ganesan YT, Dong Y, Jebiwott S, Hsieh JJ, Cheng EH. Abstract 3555: Targeting the BCL-2 family in small cell lung caner Cancer Research. 76: 3555-3555. DOI: 10.1158/1538-7445.Am2016-3555  0.482
2015 Niizuma H, Cheng EH, Hsieh JJ. Taspase 1: A protease with many biological surprises. Molecular & Cellular Oncology. 2: e999513. PMID 27308523 DOI: 10.1080/23723556.2014.999513  0.37
2015 Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH. An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nature Cell Biology. PMID 26344567 DOI: 10.1038/Ncb3236  0.735
2015 Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ. Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription. The Journal of Clinical Investigation. 125: 1203-14. PMID 25664857 DOI: 10.1172/Jci77075  0.335
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Cheng EH, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  0.726
2015 Hsieh J, Chen D, Wang P, Chen Y, Redzematovic A, Marker M, Patel P, Chevinsky M, Bhanot U, Pinciroli P, Bouvier N, Huberman KH, Berger MF, Socci ND, Cheng E, et al. Identification of efficacy biomarkers in a large metastatic renal cell carcinoma (mRCC) cohort through next generation sequencing (NGS): Results from RECORD-3. Journal of Clinical Oncology. 33: 4509-4509. DOI: 10.1200/Jco.2015.33.15_Suppl.4509  0.308
2015 Mano R, Lee W, Sankin A, Chevinsky M, Wang P, Djesevic A, Motzer R, Cheng E, Russo P, Oschwald D, Bhanot U, Tickoo S, Hakimi AA, Hsieh J. MP47-09 MOLECULAR CHARACTERIZATION OF SARCOMATOID CLEAR CELL RENAL CELL CARCINOMA Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1529  0.363
2014 Dong Y, Van Tine BA, Oyama T, Wang PI, Cheng EH, Hsieh JJ. Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis. Cell Research. 24: 1354-66. PMID 25267403 DOI: 10.1038/Cr.2014.129  0.323
2014 Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/J.Molcel.2014.08.018  0.454
2014 Liu H, Westergard TD, Cashen A, Piwnica-Worms DR, Kunkle L, Vij R, Pham CG, DiPersio J, Cheng EH, Hsieh JJ. Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4. Cancer Cell. 25: 530-42. PMID 24735925 DOI: 10.1016/J.Ccr.2014.03.008  0.433
2014 Ren D, Sun J, Wang C, Ye H, Mao L, Cheng EH, Bell GI, Polonsky KS. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency. Diabetes. 63: 2744-50. PMID 24658302 DOI: 10.2337/Db13-1513  0.443
2013 Oyama T, Sasagawa S, Takeda S, Hess RA, Lieberman PM, Cheng EH, Hsieh JJ. Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. Developmental Cell. 27: 188-200. PMID 24176642 DOI: 10.1016/J.Devcel.2013.09.025  0.337
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. Elife. 2: e00772. PMID 23991283 DOI: 10.7554/Elife.00772  0.344
2013 Takeda S, Liu H, Sasagawa S, Dong Y, Trainor PA, Cheng EH, Hsieh JJ. HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma. The Journal of Clinical Investigation. 123: 3154-65. PMID 23934123 DOI: 10.1172/Jci65566  0.349
2013 Jeng PS, Cheng EH. Cancer therapeutics: Pulling the plug on BCL-X(L). Nature Chemical Biology. 9: 351-2. PMID 23689630 DOI: 10.1038/Nchembio.1256  0.467
2013 Hakimi AA, Ostrovnaya I, Reva B, Schultz N, Chen YB, Gonen M, Liu H, Takeda S, Voss MH, Tickoo SK, Reuter VE, Russo P, Cheng EH, Sander C, Motzer RJ, et al. Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3259-67. PMID 23620406 DOI: 10.1158/1078-0432.Ccr-12-3886  0.32
2013 Bean GR, Ganesan YT, Dong Y, Takeda S, Liu H, Chan PM, Huang Y, Chodosh LA, Zambetti GP, Hsieh JJ, Cheng EH. PUMA and BIM are required for oncogene inactivation-induced apoptosis. Science Signaling. 6: ra20. PMID 23532334 DOI: 10.1126/Scisignal.2003483  0.303
2013 Hakimi AA, Chen YB, Wren J, Gonen M, Abdel-Wahab O, Heguy A, Liu H, Takeda S, Tickoo SK, Reuter VE, Voss MH, Motzer RJ, Coleman JA, Cheng EH, Russo P, et al. Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma. European Urology. 63: 848-54. PMID 23036577 DOI: 10.1016/J.Eururo.2012.09.005  0.309
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Author response: Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice Elife. DOI: 10.7554/Elife.00772.020  0.401
2013 Voss MH, Hakimi AA, Pham CG, Brannon AR, Chen Y, Cunha LF, Akin O, Liu H, Takeda S, Scott SN, Socci ND, Viale A, Schultz N, Sander C, Reuter VE, ... ... Cheng EH, et al. Abstract 3515: Pathway convergent evolution underscores treatment response to MTOR inhibitors in kidney cancers. Cancer Research. 73: 3515-3515. DOI: 10.1158/1538-7445.Am2013-3515  0.345
2013 Hakimi AA, Ostrovnaya I, Reva B, Schultz N, Chen Y, Gonen M, Liu H, Takeda S, Tickoo SK, Voss MH, Cheng EH, Reuter VE, Motzer RJ, Russo P, Hsieh JJ. 1068 ADVERSE OUTCOMES IN CLEAR CELL RENAL CELL CARCINOMA WITH MUTATIONS OF EPIGENETIC REGULATORS BAP1 AND SETD2 Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.657  0.327
2012 Zamorano S, Rojas-Rivera D, Lisbona F, Parra V, Court FA, Villegas R, Cheng EH, Korsmeyer SJ, Lavandero S, Hetz C. A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway. Plos One. 7: e37782. PMID 22719850 DOI: 10.1371/Journal.Pone.0037782  0.535
2012 Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, et al. BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α. The Embo Journal. 31: 2322-35. PMID 22510886 DOI: 10.1038/Emboj.2012.84  0.377
2012 Chen DY, Lee Y, Van Tine BA, Searleman AC, Westergard TD, Liu H, Tu HC, Takeda S, Dong Y, Piwnica-Worms DR, Oh KJ, Korsmeyer SJ, Hermone A, Gussio R, Shoemaker RH, ... Cheng EH, et al. A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth. Cancer Research. 72: 736-46. PMID 22166309 DOI: 10.1158/0008-5472.Can-11-2584  0.566
2010 Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program. Science (New York, N.Y.). 330: 1390-3. PMID 21127253 DOI: 10.1126/Science.1190217  0.715
2010 Chen DY, Liu H, Takeda S, Tu HC, Sasagawa S, Van Tine BA, Lu D, Cheng EH, Hsieh JJ. Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis. Cancer Research. 70: 5358-67. PMID 20516119 DOI: 10.1158/0008-5472.Can-10-0027  0.595
2010 Chen Y, Lewis W, Diwan A, Cheng EH, Matkovich SJ, Dorn GW. Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 107: 9035-42. PMID 20418503 DOI: 10.1073/pnas.0914013107  0.456
2009 Kim H, Tu HC, Ren D, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Molecular Cell. 36: 487-99. PMID 19917256 DOI: 10.1016/J.Molcel.2009.09.030  0.687
2009 Ren D, Kim H, Tu HC, Westergard TD, Fisher JK, Rubens JA, Korsmeyer SJ, Hsieh JJ, Cheng EH. The VDAC2-BAK rheostat controls thymocyte survival. Science Signaling. 2: ra48. PMID 19706873 DOI: 10.1126/Scisignal.2000274  0.687
2009 Kim H, Hsieh JJ, Cheng EH. Deadly splicing: Bax becomes Almighty. Molecular Cell. 33: 145-6. PMID 19187757 DOI: 10.1016/J.Molcel.2009.01.004  0.506
2009 Tu HC, Ren D, Wang GX, Chen DY, Westergard TD, Kim H, Sasagawa S, Hsieh JJ, Cheng EH. The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 106: 1093-8. PMID 19144918 DOI: 10.1073/Pnas.0808173106  0.698
2009 Cheng E. Molecular Control of Mitochondrial Apoptosis by the BCL-2 Family. Blood. 114: SCI-13-SCI-13. DOI: 10.1182/Blood.V114.22.Sci-13.Sci-13  0.578
2009 Liu H, Takeda S, Kumar R, Westergard T, Pandita T, Cheng E, Hsieh JJ. A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCFskp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication. Blood. 114: 450-450. DOI: 10.1182/Blood.V114.22.450.450  0.301
2008 Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu HC, Kim H, Cheng EH, Tjandra N, Walensky LD. BAX activation is initiated at a novel interaction site. Nature. 455: 1076-81. PMID 18948948 DOI: 10.1038/Nature07396  0.702
2008 Rotolo JA, Maj JG, Feldman R, Ren D, Haimovitz-Friedman A, Cordon-Cardo C, Cheng EH, Kolesnick R, Fuks Z. Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa. International Journal of Radiation Oncology, Biology, Physics. 70: 804-15. PMID 18191336 DOI: 10.1016/J.Ijrobp.2007.11.043  0.303
2008 Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu H, Kim H, Cheng E, Tjandra N, Walensky LD. Structural Analysis of a BAX-BIM SAHB Complex Reveals a Novel BH3 Interaction Site on BAX for Therapeutic Activation of Apoptosis Blood. 112: 300-300. DOI: 10.1182/Blood.V112.11.300.300  0.738
2006 Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nature Cell Biology. 8: 1348-58. PMID 17115033 DOI: 10.1038/Ncb1499  0.697
2006 Hsieh JJ, Takeda S, Chen DY, Westergard TD, Fisher JK, Rubens JA, Sasagawa S, Kan JT, Korsmeyer SJ, Cheng EH. Proteolysis of MLL Family Proteins Is Essential for Taspase1−Orchestrated Cell Cycle Progression. Blood. 108: 769-769. DOI: 10.1182/Blood.V108.11.769.769  0.363
2005 Ruiz-Vela A, Opferman JT, Cheng EH, Korsmeyer SJ. Proapoptotic BAX and BAK control multiple initiator caspases. Embo Reports. 6: 379-85. PMID 15776018 DOI: 10.1038/Sj.Embor.7400375  0.421
2003 Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ. VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science (New York, N.Y.). 301: 513-7. PMID 12881569 DOI: 10.1126/Science.1083995  0.449
2003 Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T, Korsmeyer SJ. BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. Science (New York, N.Y.). 300: 135-9. PMID 12624178 DOI: 10.1126/Science.1081208  0.346
2001 Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Molecular Cell. 8: 705-11. PMID 11583631 DOI: 10.1016/S1097-2765(01)00320-3  0.408
2001 Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (New York, N.Y.). 292: 727-30. PMID 11326099 DOI: 10.1126/Science.1059108  0.427
1996 Cheng EH, Levine B, Boise LH, Thompson CB, Hardwick JM. Bax-independent inhibition of apoptosis by Bcl-XL. Nature. 379: 554-6. PMID 8596636 DOI: 10.1038/379554A0  0.715
Low-probability matches (unlikely to be authored by this person)
2017 Casuscelli J, Weinhold N, Gundem G, Wang L, Zabor EC, Drill E, Wang PI, Nanjangud GJ, Redzematovic A, Nargund AM, Manley BJ, Arcila ME, Donin NM, Cheville JC, Thompson RH, ... ... Cheng EH, et al. Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma. Jci Insight. 2. PMID 28614790 DOI: 10.1172/Jci.Insight.92688  0.298
2001 Pavlov EV, Priault M, Pietkiewicz D, Cheng EH, Antonsson B, Manon S, Korsmeyer SJ, Mannella CA, Kinnally KW. A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast. The Journal of Cell Biology. 155: 725-31. PMID 11724814 DOI: 10.1083/Jcb.200107057  0.297
2016 Hsieh JJ, Chen D, Wang PI, Marker M, Redzematovic A, Chen YB, Selcuklu SD, Weinhold N, Bouvier N, Huberman KH, Bhanot U, Chevinsky MS, Patel P, Pinciroli P, Won HH, ... ... Cheng EH, et al. Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma. European Urology. PMID 27751729 DOI: 10.1016/J.Eururo.2016.10.007  0.288
2012 Cheng EH, Sawyers CL. In cancer drug resistance, germline matters too. Nature Medicine. 18: 494-6. PMID 22481406 DOI: 10.1038/Nm.2725  0.287
2016 Hsieh JJ, Cheng EH. The panoramic view of clear cell renal cell carcinoma metabolism: values of integrated global cancer metabolomics. Translational Andrology and Urology. 5: 984-986. PMID 28078239 DOI: 10.21037/Tau.2016.11.03  0.287
2013 Palaniappan KK, Hangauer MJ, Smith TJ, Smart BP, Pitcher AA, Cheng EH, Bertozzi CR, Boyce M. A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2. Cell Reports. 5: 546-52. PMID 24120863 DOI: 10.1016/J.Celrep.2013.08.048  0.287
2014 Sankin A, Hakimi AA, Mikkilineni N, Ostrovnaya I, Silk MT, Liang Y, Mano R, Chevinsky M, Motzer RJ, Solomon SB, Cheng EH, Durack JC, Coleman JA, Russo P, Hsieh JJ. The impact of genetic heterogeneity on biomarker development in kidney cancer assessed by multiregional sampling. Cancer Medicine. 3: 1485-92. PMID 25124064 DOI: 10.1002/Cam4.293  0.283
2016 Hsieh J, Chen D, Wang P, Chen Y, Marker M, Patel P, Chevinsky M, Bhanot U, Pinciroli P, Berger MF, Cheng E, Lee W, Knox JJ, Voss MH, Voi M, et al. Differential overall survival (OS) results in RECORD-3 study based on three distinct mRCC molecular subgroups classified by BAP1 and/or PBRM1 mutations. Journal of Clinical Oncology. 34: 561-561. DOI: 10.1200/Jco.2016.34.2_Suppl.561  0.282
2013 Brown SA, Cheng E, Williams MS, Winkles JA. TWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domain. Plos One. 8: e65248. PMID 23750247 DOI: 10.1371/Journal.Pone.0065248  0.271
2020 Hayashi T, Odintsov I, Smith RS, Ishizawa K, Liu AJW, Delasos L, Kurzatkowski C, Tai H, Gladstone E, Vojnic M, Kohsaka S, Suzawa K, Liu Z, Kunte S, Mattar MS, ... ... Cheng E, et al. RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation. Disease Models & Mechanisms. PMID 33318047 DOI: 10.1242/dmm.047779  0.263
2016 Somwar R, Smith R, Hayashi T, Ishizawa K, Snyder Charen A, Khodos I, Mattar M, He J, Balasubramanian S, Stephens P, Lipson D, de Stanchina E, Davare M, Miller VA, Riely GJ, ... ... Cheng E, et al. MDM2 amplification (Amp) to mediate cabozantinib resistance in patients (Pts) with advanced RET-rearranged lung cancers. Journal of Clinical Oncology. 34: 9068-9068. DOI: 10.1200/Jco.2016.34.15_Suppl.9068  0.258
2006 Takeda S, Chen DY, Westergard TD, Fisher JK, Rubens JA, Sasagawa S, Kan JT, Korsmeyer SJ, Cheng EH, Hsieh JJ. Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. Genes & Development. 20: 2397-409. PMID 16951254 DOI: 10.1101/Gad.1449406  0.258
2021 Tanaka K, Yu HA, Yang S, Han S, Selcuklu SD, Kim K, Ramani S, Ganesan YT, Moyer A, Sinha S, Xie Y, Ishizawa K, Osmanbeyoglu HU, Lyu Y, Roper N, ... ... Cheng EH, et al. Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis. Cancer Cell. PMID 34388376 DOI: 10.1016/j.ccell.2021.07.006  0.246
2013 Zhou H, Ekmekcioglu S, Marks JW, Mohamedali KA, Asrani K, Phillips KK, Brown SA, Cheng E, Weiss MB, Hittelman WN, Tran NL, Yagita H, Winkles JA, Rosenblum MG. The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment. The Journal of Investigative Dermatology. 133: 1052-62. PMID 23190886 DOI: 10.1038/Jid.2012.402  0.238
2019 Takashima S, Martin ML, Jansen SA, Fu Y, Bos J, Chandra D, O'Connor MH, Mertelsmann AM, Vinci P, Kuttiyara J, Devlin SM, Middendorp S, Calafiore M, Egorova A, Kleppe M, ... ... Cheng EH, et al. T cell-derived interferon-γ programs stem cell death in immune-mediated intestinal damage. Science Immunology. 4. PMID 31811055 DOI: 10.1126/Sciimmunol.Aay8556  0.238
2020 Hsieh JJ, Cheng EH. Exploiting the circuit breaker cancer evolution model in human clear cell renal cell carcinoma. Cell Stress. 4: 191-198. PMID 32743344 DOI: 10.15698/cst2020.08.227  0.237
2007 Liu H, Chen D, Westergard T, Takeda S, Sasagawa S, Cheng EH, Hsieh JJ. Bimodal Degradation of MLL Protein by the Cell Cycle SCFSkp2 and APCCdc20 E3 Lilgases Assures Cell Cycle Execution: A Critical Regulatory Circuit Lost in Leukemogenic MLL-Fusions. Blood. 110: 828-828. DOI: 10.1182/Blood.V110.11.828.828  0.235
2023 Shapiro DD, Zacharias NM, Tripathi DN, Karki M, Bertocchio JP, Soeung M, He R, Westerman ME, Gao J, Rao P, Lam TNA, Jonasch E, Perelli L, Cheng EH, Carugo A, et al. Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy. Clinical and Translational Medicine. 13: e1267. PMID 37226898 DOI: 10.1002/ctm2.1267  0.234
2022 Xie Y, Sahin M, Sinha S, Wang Y, Nargund AM, Lyu Y, Han S, Dong Y, Hsieh JJ, Leslie CS, Cheng EH. SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes. Nature Cancer. PMID 35115713 DOI: 10.1038/s43018-021-00316-3  0.233
2013 Cheng E, Armstrong CL, Galisteo R, Winkles JA. TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic. Frontiers in Immunology. 4: 473. PMID 24391646 DOI: 10.3389/Fimmu.2013.00473  0.227
2008 Liu H, Takeda S, Cheng EH, Hsieh JJ. Biphasic MLL takes helm at cell cycle control: implications in human mixed lineage leukemia. Cell Cycle (Georgetown, Tex.). 7: 428-35. PMID 18235233 DOI: 10.4161/Cc.7.4.5426  0.223
2014 Voss MH, Hakimi AA, Pham CG, Brannon AR, Chen YB, Cunha LF, Akin O, Liu H, Takeda S, Scott SN, Socci ND, Viale A, Schultz N, Sander C, Reuter VE, ... ... Cheng EH, et al. Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1955-64. PMID 24622468 DOI: 10.1158/1078-0432.CCR-13-2345  0.215
2019 Melero M, Hou A, Cheng E, Tayade A, Lee SC, Unberath M, Navab N. Upbeat: Augmented Reality-Guided Dancing for Prosthetic Rehabilitation of Upper Limb Amputees. Journal of Healthcare Engineering. 2019: 2163705. PMID 31015903 DOI: 10.1155/2019/2163705  0.211
2012 Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, Hostetter G, Weiss GJ, Kingsley CB, Loftus JC, Bremner R, Tran NL, Winkles JA. Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion. The American Journal of Pathology. 181: 111-20. PMID 22634180 DOI: 10.1016/J.Ajpath.2012.03.026  0.21
2023 Soeung M, Perelli L, Chen Z, Dondossola E, Ho IL, Carbone F, Zhang L, Khan H, Le CN, Zhu C, Peoples MD, Feng N, Jiang S, Zacharias NM, Minelli R, ... ... Cheng EH, et al. SMARCB1 regulates the hypoxic stress response in sickle cell trait. Proceedings of the National Academy of Sciences of the United States of America. 120: e2209639120. PMID 37186844 DOI: 10.1073/pnas.2209639120  0.208
2007 Liu H, Cheng EH, Hsieh JJ. Bimodal degradation of MLL by SCFSkp2 and APCCdc20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions. Genes & Development. 21: 2385-98. PMID 17908926 DOI: 10.1101/gad.1574507  0.201
2022 Miheecheva N, Postovalova E, Lyu Y, Ramachandran A, Bagaev A, Svekolkin V, Galkin I, Zyrin V, Maximov V, Lozinsky Y, Isaev S, Ovcharov P, Shamsutdinova D, Cheng EH, Nomie K, et al. Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity. Cell Reports. 40: 111180. PMID 35977503 DOI: 10.1016/j.celrep.2022.111180  0.187
2023 Miyazaki I, Odintsov I, Ishida K, Lui AJW, Kato M, Suzuki T, Zhang T, Wakayama K, Kurth RI, Cheng R, Fujita H, Delasos L, Vojnic M, Khodos I, Yamada Y, ... ... Cheng EH, et al. Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations. Nature Cancer. 4: 1345-1361. PMID 37743366 DOI: 10.1038/s43018-023-00630-y  0.181
2023 Xie Y, Sahin M, Wakamatsu T, Inoue-Yamauchi A, Zhao W, Han S, Nargund AM, Yang S, Lyu Y, Hsieh JJ, Leslie CS, Cheng EH. SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis. Jci Insight. 8. PMID 36810256 DOI: 10.1172/jci.insight.154120  0.174
2008 Liu H, Westergard TD, Chen DY, Cheng EH, Hsieh JJ. The Role of MLL in DNA Damage Checkpoint and Its Implication in Leukemogenesis Blood. 112: 5332-5332. DOI: 10.1182/blood.V112.11.5332.5332  0.172
2009 Liu H, Cheng EH, Hsieh JJ. MLL fusions: pathways to leukemia. Cancer Biology & Therapy. 8: 1204-11. PMID 19729989  0.17
2015 Chen SM, Lee MS, Chang CY, Lin SZ, Cheng EH, Liu YH, Pan HC, Lee HC, Su HL. Prerequisite OCT4 Maintenance Potentiates the Neural Induction of Differentiating Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. Cell Transplantation. 24: 829-44. PMID 24256943 DOI: 10.3727/096368913X675179  0.161
1980 Bart RS, Porzio NR, Kopf AW, Cheng EH, Farcet Y, Vilcek JT. Inhibition of growth of b16 murine malignant melanoma by exogenous interferon Cancer Research. 40: 614-619. PMID 6162552  0.16
1985 Yang JL, Cheng EH, Capizzi RL, Kute T. Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia Journal of Clinical Investigation. 75: 141-146. PMID 4038404  0.159
2023 Elkrief A, Odintsov I, Markov V, Caeser R, Sobczuk P, Tischfield SE, Bhanot U, Vanderbilt CM, Cheng E, Drilon A, Riely GJ, Lockwood WW, de Stanchina E, Tirunagaru VG, Doebele RC, et al. Combination therapy with MDM2 and MEK inhibitors is effective in patient-derived models of lung adenocarcinoma with concurrent oncogenic drivers and MDM2 amplification. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37182602 DOI: 10.1016/j.jtho.2023.05.007  0.156
2010 Liu H, Takeda S, Kumar R, Westergard TD, Brown EJ, Pandita TK, Cheng EH, Hsieh JJ. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature. 467: 343-6. PMID 20818375 DOI: 10.1038/Nature09350  0.155
2010 Tsai TC, Lin W, Yang SH, Cheng WTK, Cheng EH, Lee MS, Chong KY, Chen CM. Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition Bmc Developmental Biology. 10. PMID 20704734 DOI: 10.1186/1471-213X-10-88  0.153
2007 Er HM, Cheng EH, Radhakrishnan AK. Anti-proliferative and mutagenic activities of aqueous and methanol extracts of leaves from Pereskia bleo (Kunth) DC (Cactaceae) Journal of Ethnopharmacology. 113: 448-456. PMID 17698306 DOI: 10.1016/j.jep.2007.06.026  0.153
2021 Niizuma H, Searleman AC, Takeda S, Armstrong SA, Park CY, Cheng EH, Hsieh JJ. Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates through cleaving TFIIA. Jci Insight. PMID 34156981 DOI: 10.1172/jci.insight.149382  0.151
2003 Hsieh JJ, Cheng EH, Korsmeyer SJ. Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression. Cell. 115: 293-303. PMID 14636557 DOI: 10.1016/S0092-8674(03)00816-X  0.142
2011 Gonzalez-Suarez I, Redwood AB, Grotsky DA, Neumann MA, Cheng EH, Stewart CL, Dusso A, Gonzalo S. A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair. The Embo Journal. 30: 3383-96. PMID 21750527 DOI: 10.1038/Emboj.2011.225  0.138
2022 Lee CH, Gundem G, Lee W, Chen YB, Cross JR, Dong Y, Redzematovic A, Mano R, Wei EY, Cheng EH, Srinivasan R, Oschwald D, Hakimi AA, Dunphy MP, Linehan WM, et al. Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal -Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg Effect. Jco Precision Oncology. 1: 1-14. PMID 35172488 DOI: 10.1200/PO.16.00007  0.137
2015 Cheng E, Whitsett TG, Tran NL, Winkles JA. The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion. Molecular Cancer Research : McR. 13: 575-83. PMID 25392346 DOI: 10.1158/1541-7786.Mcr-14-0411  0.137
2023 Miyazaki I, Odintsov I, Ishida K, Lui AJW, Kato M, Suzuki T, Zhang T, Wakayama K, Kurth RI, Cheng R, Fujita H, Delasos L, Vojnic M, Khodos I, Yamada Y, ... ... Cheng EH, et al. Author Correction: Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations. Nature Cancer. 4: 1526. PMID 37814012 DOI: 10.1038/s43018-023-00663-3  0.122
2015 Schneider CS, Perez JG, Cheng E, Zhang C, Mastorakos P, Hanes J, Winkles JA, Woodworth GF, Kim AJ. Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells. Biomaterials. 42: 42-51. PMID 25542792 DOI: 10.1016/J.Biomaterials.2014.11.054  0.12
2024 Zhu A, Strasser MO, McClure TD, Gereta S, Cheng E, Pandit K, Hu JC. Comparative Effectiveness of Partial Gland Cryoablation Versus Robotic Radical Prostatectomy for Cancer Control. European Urology Focus. PMID 38677913 DOI: 10.1016/j.euf.2024.04.008  0.12
1992 Shaw RD, Groene WS, Mackow ER, Merchant AA, Cheng EH. Recombinant baculovirus-expressed rotavirus protein (VP4) in an ELISPOT assay of antibody secretion Viral Immunology. 5: 51-59. PMID 1319171 DOI: 10.1089/Vim.1992.5.51  0.116
1994 Gu J, Cheng EH, Xu B. Effect of α-anordrin on erythrocyte membrane and calmodulin function Chinese Pharmacological Bulletin. 10: 177-179.  0.116
1991 Shaw RD, Groene WS, Mackow ER, Merchant AA, Cheng EH. VP4-Specific Intestinal Antibody Response to Rotavirus in a Murine Model of Heterotypic Infection Journal of Virology. 65: 3052-3059. PMID 1709695 DOI: 10.1128/Jvi.65.6.3052-3059.1991  0.095
2013 Cheng EH, Chen SU, Lee TH, Pai YP, Huang LS, Huang CC, Lee MS. Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo quality. Human Reproduction (Oxford, England). 28: 929-36. PMID 23377770 DOI: 10.1093/humrep/det004  0.094
2021 Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, et al. BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α. The Embo Journal. 40: e109146. PMID 34523136 DOI: 10.15252/embj.2021109146  0.089
1991 Merchant AA, Groene WS, Cheng EH, Shaw RD. Murine intestinal antibody response to heterologous rotavirus infection Journal of Clinical Microbiology. 29: 1693-1701. PMID 1761691  0.086
2016 Carbone EJ, Rajpura K, Allen BN, Cheng E, Ulery BD, Lo KW. Osteotropic Nanoscale Drug Delivery Systems Based On Small Molecule Bone-Targeting Moieties. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27562211 DOI: 10.1016/J.Nano.2016.08.015  0.076
2022 Tzeng M, Basourakos SP, Davuluri M, Nagar H, Ramaswamy A, Cheng E, DeMeo G, Hu JC. Evolving Trends in the Management of Low-Risk Prostate Cancer. Clinical Genitourinary Cancer. PMID 35701333 DOI: 10.1016/j.clgc.2022.05.004  0.075
2012 Chan CK, Wu KH, Lee YS, Hwang SM, Lee MS, Liao SK, Cheng EH, See LC, Tsai CN, Kuo ML, Huang JL. The comparison of interleukin 6-associated immunosuppressive effects of human ESCs, fetal-type MSCs, and adult-type MSCs. Transplantation. 94: 132-8. PMID 22766769 DOI: 10.1097/TP.0b013e31825940a4  0.072
1993 Shaw RD, Merchant AA, Groene WS, Cheng EH. Persistence of intestinal antibody response to heterologous rotavirus infection in a murine model beyond 1 year Journal of Clinical Microbiology. 31: 188-191. PMID 8381806  0.072
2008 Cheng EH, Chen W, Chang SY, Huang JJ, Huang CC, Huang LS, Liu CH, Lee MS. Blastocoel volume is related to successful establishment of human embryonic stem cell lines Reproductive Biomedicine Online. 17: 436-444. PMID 18765016 DOI: 10.1016/S1472-6483(10)60229-5  0.071
2022 Borregales LD, DeMeo G, Gu X, Cheng E, Dudley V, Schaeffer EM, Nagar H, Carlsson S, Vickers A, Hu JC. Grade Migration of Prostate Cancer in the United States during the last decade. Journal of the National Cancer Institute. PMID 35348709 DOI: 10.1093/jnci/djac066  0.07
1976 Thompson KS, Cheng EH. A computer package to facilitate compliance with utilization review requirements. Hospital & Community Psychiatry. 27: 653-6. PMID 786846  0.068
2013 Keeney M, Mathur M, Cheng E, Tong X, Yang F. Effects of polymer end-group chemistry and order of deposition on controlled protein delivery from layer-by-layer assembly Biomacromolecules. 14: 794-800. PMID 23360295 DOI: 10.1021/bm3018559  0.065
2010 Lee MS, Liu CH, Lee TH, Wu HM, Huang CC, Huang LS, Chen CM, Cheng EH. Association of creatin kinase B and peroxiredoxin 2 expression with age and embryo quality in cumulus cells. Journal of Assisted Reproduction and Genetics. 27: 629-39. PMID 20721618 DOI: 10.1007/s10815-010-9459-7  0.054
2015 Hendy P, Cheng EH, Livsey R, Mortimore M. Curative embolization of an inferior mesenteric arteriovenous fistula causing ischaemic proctosigmoiditis. Anz Journal of Surgery. PMID 26464286 DOI: 10.1111/ans.13346  0.054
1993 Schwab KS, Cheng EH. “Postgastrectomy” bezoar secondary to gastric cancer Journal of Clinical Gastroenterology. 16: 45-47. PMID 8421145  0.05
1990 Cheng EH, Pavelock RR. Multiple gastrointestinal tract diverticula Gastrointestinal Radiology. 15: 282-284. PMID 2120099 DOI: 10.1007/BF01888797  0.046
2019 Li ZN, Cheng E, Poirot E, Weber KM, Carney P, Chang J, Liu F, Gross FL, Holiday C, Fry A, Stevens J, Tumpey T, Levine MZ. Identification of novel influenza A virus exposures by an improved high-throughput multiplex MAGPIX platform and serum adsorption. Influenza and Other Respiratory Viruses. PMID 31701647 DOI: 10.1111/irv.12695  0.043
2013 Cheng EH, Tsai TL, Lin MJ, Wu XR, Yeh NM, Pan BW, Chen YC, Kuo SN. Study of using internal thread whirling in machining titanium dental implant Applied Mechanics and Materials. 268: 436-441. DOI: 10.4028/www.scientific.net/AMM.268-270.436  0.043
2015 Liu Y, Cheng E, Rakotondraibe LH, Brodie PJ, Applequist W, Randrianaivo R, Rakotondrafara A, Ratsimbason M, Rasamison VE, Kingston DG. Antiproliferative Compounds from Ocotea macrocarpa from the Madagascar Dry Forest(1). Tetrahedron Letters. 56: 3630-3632. PMID 26034338 DOI: 10.1016/J.Tetlet.2015.01.172  0.04
2012 Cheng EH, Lin MJ, Shiu SY, Tsai TL, Chen YC. Study of screw loosening in abutment subject to occlusal loading Advanced Materials Research. 415: 2166-2171. DOI: 10.4028/www.scientific.net/AMR.415-417.2166  0.039
2008 Huang LS, Lee MS, Cheng EH, Lee TH, Liu CH, Lee MC, Chou MC. Recipient age and pulsatility index affect uterine receptivity in oocyte donation programmes Reproductive Biomedicine Online. 17: 94-100. PMID 18616897 DOI: 10.1016/S1472-6483(10)60299-4  0.039
2021 Cheng E, Davuluri M, Lewicki PJ, Hu JC, Basourakos SP. Developments in optimizing transperineal prostate biopsy. Current Opinion in Urology. PMID 34783715 DOI: 10.1097/MOU.0000000000000947  0.038
2008 Cheng EH, Fan YG, Zhou SP. Application of expert systems for corrosion and protection Corrosion and Protection. 29: 167-169.  0.038
2017 Wu AS, Small Iv W, Bryson TM, Cheng E, Metz TR, Schulze SE, Duoss EB, Wilson TS. 3D Printed Silicones with Shape Memory. Scientific Reports. 7: 4664. PMID 28680078 DOI: 10.1038/s41598-017-04663-z  0.037
2022 Borregales LD, DeMeo G, Gu X, Cheng E, Dudley V, Schaeffer EM, Nagar H, Carlsson S, Vickers A, Hu JC. Response to Takahashi. Journal of the National Cancer Institute. PMID 35880831 DOI: 10.1093/jnci/djac146  0.035
2015 Hussain SA, Zhou R, Jacobson C, Weng J, Cheng E, Lay J, Hung P, Lerner JT, Sankar R. Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox-Gastaut syndrome. Epilepsy & Behavior : E&B. 47: 138-41. PMID 25935511 DOI: 10.1016/J.Yebeh.2015.04.009  0.035
1989 Cheng EH, Bermanski P, Silversmith M, Valenstein P, Kawanishi H. Prevalence of Campylobacter pylori in esophagitis, gastritis, and duodenal disease Archives of Internal Medicine. 149: 1373-1375. PMID 2730254  0.033
2014 Lin MJ, Tsai TL, Wu XR, Cheng EH, Yeh NM. Development of a transducer for dental implant stability measurement Applied Mechanics and Materials. 511: 265-269. DOI: 10.4028/www.scientific.net/AMM.511-512.265  0.033
2012 Cheng EH, Lin MJ, Tsai TL, Yeh NM. Study on machining dental implants by whirling approach Applied Mechanics and Materials. 117: 1506-1513. DOI: 10.4028/www.scientific.net/AMM.117-119.1506  0.03
2023 Kam CCS, Cheng EH, Cui T. Measuring Self-Esteem with Expanded Format in a Fraction of Time: ESE-S and ESE-US. Journal of Personality Assessment. 1-12. PMID 37782046 DOI: 10.1080/00223891.2023.2259990  0.026
2023 Scambler S, Ahmed TA, Aiyere J, Cheng E. Diversifying the dental curriculum: A review of the Bachelor of Dental Surgery degree reading lists in a UK dental school. European Journal of Dental Education : Official Journal of the Association For Dental Education in Europe. PMID 37147927 DOI: 10.1111/eje.12915  0.024
2011 Cheng AY, Hamid NRA, Cheng EH. Risk perception of the E-Payment systems: A young adult perspective Recent Researches in Artificial Intelligence, Knowledge Engineering and Data Bases - 10th Wseas International Conference On Artificial Intelligence, Knowledge Engineering and Data Bases, Aiked'11. 121-127.  0.022
2017 Hussain SA, Lay J, Cheng E, Weng J, Sankar R, Baca CB. Recognition of Infantile Spasms Is Often Delayed: The ASSIST Study. The Journal of Pediatrics. 190: 215-221.e1. PMID 29144248 DOI: 10.1016/J.Jpeds.2017.08.009  0.019
2022 Basourakos SP, Alshak MN, Lewicki PJ, Cheng E, Tzeng M, DeRosa AP, Allaway MJ, Ross AE, Schaeffer EM, Patel HD, Hu JC, Gorin MA. Role of Prophylactic Antibiotics in Transperineal Prostate Biopsy: A Systematic Review and Meta-analysis. European Urology Open Science. 37: 53-63. PMID 35243391 DOI: 10.1016/j.euros.2022.01.001  0.018
1989 Cheng EH, Brugge WR. Filiform polyposis in a patient without history of inflammatory bowel disease: To the editor Journal of Clinical Gastroenterology. 11: 479-481. PMID 2788185  0.014
1995 Brummer B, Cheng EH. Simple external retention device for foley replacement gastrostomy tubes Journal of Clinical Gastroenterology. 20: 337-338. PMID 7665830  0.013
1973 Cheng EH, Ozisik MN. HEAT TRANSFER IN A RADIATING, NONSTEADY, THREE-DIMENSIONAL STAGNATION FLOW Applied Scientific Research (the Hague). 28: 185-197. DOI: 10.1007/BF00413066  0.013
2023 Cheng E, Gereta S, Zhang TR, Zhu A, Basourakos SP, McKernan C, Xie S, Vickers AJ, Laviana AA, Hu JC. Same-day Discharge versus Inpatient Robotic Assisted Radical Prostatectomy: Complications, Time-Driven Activity-Based Costing, and Patient Satisfaction. The Journal of Urology. 101097JU000000000000. PMID 37639456 DOI: 10.1097/JU.0000000000003678  0.013
2021 Basourakos SP, Lewicki PJ, Ramaswamy A, Cheng E, Dudley V, Yu M, Karir B, Hung AJ, Khani F, Hu JC. Clipless Robotic-assisted Radical Prostatectomy and Impact on Outcomes. European Urology Focus. PMID 34246618 DOI: 10.1016/j.euf.2021.06.010  0.012
1990 Cheng EH, Silversmith M, Bermanski P. Prevalence of Campylobacter pylori in a tertiary care hospital in the Mid-Atlantic United States (I: Reply) Archives of Internal Medicine. 150: 1134.  0.01
2023 Ma R, Cen S, Forsyth E, Probst P, Asghar A, Townsend W, Hui A, Desai A, Tzeng M, Cheng E, Ramaswamy A, Wagner C, Hu JC, Hung AJ. Technical surgical skill assessment of neurovascular bundle dissection and urinary continence recovery after robotic-assisted radical prostatectomy. Ju Open Plus. 1. PMID 38187460 DOI: 10.1097/ju9.0000000000000035  0.01
2023 Cheng E, Gereta S, Zhang TR, Zhu A, Basourakos SP, McKernan C, Xie S, Vickers AJ, Laviana AA, Hu JC. Reply by Authors. The Journal of Urology. 101097JU000000000000. PMID 37747136 DOI: 10.1097/JU.0000000000003678.03  0.01
2022 Zietz S, Cheng E, Lansford JE, Deater-Deckard K, Di Giunta L, Dodge KA, Gurdal S, Liu Q, Long Q, Oburu P, Pastorelli C, Skinner AT, Sorbring E, Steinberg L, Tapanya S, et al. Positive parenting, adolescent adjustment, and quality of adolescent diet in nine countries. Journal of Adolescence. PMID 36067124 DOI: 10.1002/jad.12089  0.01
2020 Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, et al. Transcriptomic data from the rat liver after five days of exposure to legacy or emerging brominated flame retardants. Data in Brief. 32: 106136. PMID 32904430 DOI: 10.1016/j.dib.2020.106136  0.01
2020 Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, et al. Comparative Toxicity and Liver Transcriptomics of Legacy and Emerging Brominated Flame Retardants following 5-Day Exposure in the Rat. Toxicology Letters. PMID 32679240 DOI: 10.1016/j.toxlet.2020.07.016  0.01
2020 Cheng E, Gambhirrao N, Patel R, Zhowandai A, Rychtář J, Taylor D. A game-theoretical analysis of Poliomyelitis vaccination. Journal of Theoretical Biology. 110298. PMID 32371008 DOI: 10.1016/j.jtbi.2020.110298  0.01
2004 Shenaq SM, Kim JY, Armenta AH, Nath RK, Cheng E, Jedrysiak A. The Surgical Treatment of Obstetric Brachial Plexus Palsy. Plastic and Reconstructive Surgery. 113: 54E-67E. PMID 15083009  0.01
2003 Li SB, Cheng EH. Treatment of liquefying sandy soil under aircraft parking area for South Airline Company of Guangzhou airport by dynamic compaction Renmin Changjiang/Yangtze River. 34: 6.  0.01
1993 Schwab KS, Cheng EH. Endoscopic removal of a penetrating surgical clip from the esophagus [9] Gastrointestinal Endoscopy. 39: 860. PMID 8293930  0.01
1990 Merchant AA, Cheng EH. Delayed splenic rupture after colonoscopy American Journal of Gastroenterology. 85: 906-907. PMID 2371998  0.01
1972 Cheng EH, Özişik MN. Radiation with free convection in an absorbing, emitting and scattering medium International Journal of Heat and Mass Transfer. 15: 1243-1252. DOI: 10.1016/0017-9310(72)90188-3  0.01
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