Paul L. Huang - Publications

Affiliations: 
Engineering and Applied Sciences Harvard University, Cambridge, MA, United States 
Area:
Biomedical Engineering, Cell Biology

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shvedova M, Litvak MM, Roberts JD, Fukumura D, Suzuki T, Şencan İ, Li G, Reventun P, Buys ES, Kim HH, Sakadžić S, Ayata C, Huang PL, Feil R, Atochin DN. cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19870583. PMID 31423931 DOI: 10.1177/0271678X19870583  0.357
2019 Shvedova M, Roberts JD, Huang PL, Feil R, Atochin DN. Abstract WMP83: cGMP-Dependent Protein Kinase I in Smooth Muscle Cells Protects Against Stroke in Female Mice Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wmp83  0.329
2018 Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ, Baur JA, Atochin DN, ... Huang PL, et al. Oral nitrite restores age-dependent phenotypes in eNOS-null mice. Jci Insight. 3. PMID 30135317 DOI: 10.1172/Jci.Insight.122156  0.379
2018 Sellers SL, Milad N, Chan R, Mielnik M, Jermilova U, Huang PL, de Crom R, Hirota JA, Hogg JC, Sandor GG, Van Breemen C, Esfandiarei M, Seidman MA, Bernatchez P. Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function. The American Journal of Pathology. PMID 29433732 DOI: 10.1016/J.Ajpath.2017.11.006  0.38
2016 Tanigaki K, Chambliss KL, Yuhanna IS, Sacharidou A, Ahmed M, Atochin DN, Huang PL, Shaul PW, Mineo C. Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice. Diabetes. PMID 27207525 DOI: 10.2337/Db15-1605  0.354
2016 Park K, Mima A, Li Q, Rask-Madsen C, He P, Mizutani K, Katagiri S, Maeda Y, Wu IH, Khamaisi M, Preil SR, Maddaloni E, Sørensen D, Rasmussen LM, Huang PL, et al. Insulin decreases atherosclerosis by inducing endothelin receptor B expression. Jci Insight. 1. PMID 27200419 DOI: 10.1172/Jci.Insight.86574  0.356
2016 Atochin DN, Schepetkin IA, Khlebnikov AI, Seledtsov VI, Swanson H, Quinn MT, Huang PL. A Novel Dual NO-donating Oxime and c-Jun N-terminal Kinase Inhibitor Protects Against Cerebral Ischemia-Reperfusion Injury in Mice. Neuroscience Letters. PMID 26923672 DOI: 10.1016/J.Neulet.2016.02.033  0.405
2015 Lu Y, Wei J, Stec DE, Roman RJ, Ge Y, Cheng L, Liu EY, Zhang J, Hansen PB, Fan F, Juncos LA, Wang L, Pollock J, Huang PL, Fu Y, et al. Macula Densa Nitric Oxide Synthase 1β Protects against Salt-Sensitive Hypertension. Journal of the American Society of Nephrology : Jasn. PMID 26647426 DOI: 10.1681/Asn.2015050515  0.423
2015 Froehner SC, Reed SM, Anderson KN, Huang PL, Percival JM. Loss of nNOS inhibits compensatory muscle hypertrophy and exacerbates inflammation and eccentric contraction-induced damage in mdx mice. Human Molecular Genetics. 24: 492-505. PMID 25214536 DOI: 10.1093/Hmg/Ddu469  0.331
2014 Shin HK, Oka F, Kim JH, Atochin D, Huang PL, Ayata C. Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15200-7. PMID 25392489 DOI: 10.1523/Jneurosci.1110-14.2014  0.405
2014 King AL, Polhemus DJ, Bhushan S, Otsuka H, Kondo K, Nicholson CK, Bradley JM, Islam KN, Calvert JW, Tao YX, Dugas TR, Kelley EE, Elrod JW, Huang PL, Wang R, et al. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proceedings of the National Academy of Sciences of the United States of America. 111: 3182-7. PMID 24516168 DOI: 10.1073/Pnas.1321871111  0.364
2014 Pong T, Scherrer-Crosbie M, Atochin DN, Bloch KD, Huang PL. Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. Plos One. 9: e85946. PMID 24465805 DOI: 10.1371/Journal.Pone.0085946  0.693
2014 Shin HK, Huang PL, Ayata C. Rho-kinase inhibition improves ischemic perfusion deficit in hyperlipidemic mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 284-7. PMID 24192634 DOI: 10.1038/Jcbfm.2013.195  0.392
2013 Shuvaev VV, Han J, Tliba S, Arguiri E, Christofidou-Solomidou M, Ramirez SH, Dykstra H, Persidsky Y, Atochin DN, Huang PL, Muzykantov VR. Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo. Plos One. 8: e77002. PMID 24146950 DOI: 10.1371/Journal.Pone.0077002  0.371
2013 Di Lorenzo A, Lin MI, Murata T, Landskroner-Eiger S, Schleicher M, Kothiya M, Iwakiri Y, Yu J, Huang PL, Sessa WC. eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases. Journal of Cell Science. 126: 5541-52. PMID 24046447 DOI: 10.1242/Jcs.115972  0.378
2013 Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL. Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size. Stroke; a Journal of Cerebral Circulation. 44: 3183-8. PMID 23988642 DOI: 10.1161/Strokeaha.113.002073  0.392
2013 Li Q, Park K, Li C, Rask-Madsen C, Mima A, Qi W, Mizutani K, Huang P, King GL. Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium. Circulation Research. 113: 418-27. PMID 23759514 DOI: 10.1161/Circresaha.113.301074  0.426
2013 Hyndman KA, Boesen EI, Elmarakby AA, Brands MW, Huang P, Kohan DE, Pollock DM, Pollock JS. Renal collecting duct nos1 maintains fluid-electrolyte homeostasis and blood pressure Hypertension. 62: 91-98. PMID 23608660 DOI: 10.1161/Hypertensionaha.113.01291  0.339
2013 Ayata C, Shin HK, Dileköz E, Atochin DN, Kashiwagi S, Eikermann-Haerter K, Huang PL. Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 954-62. PMID 23486293 DOI: 10.1038/Jcbfm.2013.38  0.376
2013 Huang S, Kim JK, Atochin DN, Farrar CT, Huang PL, Suh JY, Kwon SJ, Shim WH, Cho H, Cho G, Kim YR. Cerebral blood volume affects blood-brain barrier integrity in an acute transient stroke model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 898-905. PMID 23462571 DOI: 10.1038/Jcbfm.2013.27  0.311
2013 Park JW, Piknova B, Huang PL, Noguchi CT, Schechter AN. Effect of blood nitrite and nitrate levels on murine platelet function. Plos One. 8: e55699. PMID 23383344 DOI: 10.1371/Journal.Pone.0055699  0.302
2013 Kashiwagi S, Atochin DN, Li Q, Schleicher M, Pong T, Sessa WC, Huang PL. ENOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity Biochemical and Biophysical Research Communications. 431: 284-290. PMID 23291238 DOI: 10.1016/J.Bbrc.2012.12.110  0.685
2013 Tanigaki K, Vongpatanasin W, Barrera JA, Atochin DN, Huang PL, Bonvini E, Shaul PW, Mineo C. C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. 62: 721-31. PMID 23069625 DOI: 10.2337/Db12-0133  0.342
2012 Ponnuswamy P, Schröttle A, Ostermeier E, Grüner S, Huang PL, Ertl G, Hoffmann U, Nieswandt B, Kuhlencordt PJ. eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice. Plos One. 7: e30193. PMID 22291917 DOI: 10.1371/Journal.Pone.0030193  0.378
2012 Pointer MA, Daumerie G, Bridges L, Yancey S, Howard K, Davis W, Huang P, Loscalzo J. Physiological stress increases renal injury in eNOS-knockout mice. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 35: 318-24. PMID 22170389 DOI: 10.1038/Hr.2011.185  0.329
2011 MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proceedings of the National Academy of Sciences of the United States of America. 108: E1137-45. PMID 21949402 DOI: 10.1073/Pnas.1104357108  0.46
2011 Kurtz B, Thibault HB, Raher MJ, Popovich JR, Cawley S, Atochin DN, Hayton S, Shakartzi HR, Huang PL, Bloch KD, Buys E, Scherrer-Crosbie M. Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance. American Journal of Physiology. Heart and Circulatory Physiology. 301: H2093-101. PMID 21856905 DOI: 10.1152/Ajpheart.00744.2010  0.302
2011 Newfell BG, Iyer LK, Mohammad NN, McGraw AP, Ehsan A, Rosano G, Huang PL, Mendelsohn ME, Jaffe IZ. Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1871-80. PMID 21617142 DOI: 10.1161/Atvbaha.111.229070  0.315
2011 Ling Y, Pong T, Vassiliou CC, Huang PL, Cima MJ. Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers. Nature Biotechnology. 29: 273-7. PMID 21317907 DOI: 10.1038/Nbt.1780  0.644
2011 Atochin DN, Huang PL. Role of endothelial nitric oxide in cerebrovascular regulation. Current Pharmaceutical Biotechnology. 12: 1334-42. PMID 21235451 DOI: 10.2174/138920111798280974  0.373
2011 Chernigovskaya E, Atochin D, Yamova L, Huang P, Glazova M. Immunohistochemical expression of Bcl-2, p53 and caspase-9 in hypothalamus magnocellular centers of nNOS knockout mice following water deprivation Biotechnic & Histochemistry. 86: 333-339. PMID 20662604 DOI: 10.3109/10520295.2010.501706  0.385
2011 Chernigovskaya EV, Yamova LA, Atochin D, Huang P, Glazova MV. Interaction of neuronal NOS and catecholamines in regulation of expression of proteins of apoptosis by vasopressinergic hypothalamic neurons Journal of Evolutionary Biochemistry and Physiology. 47: 275-283. DOI: 10.1134/S0022093011030078  0.318
2010 Atochin DN, Huang PL. Endothelial nitric oxide synthase transgenic models of endothelial dysfunction. PflüGers Archiv : European Journal of Physiology. 460: 965-74. PMID 20697735 DOI: 10.1007/S00424-010-0867-4  0.444
2010 Atochin DN, Yuzawa I, Li Q, Rauwerdink KM, Malhotra R, Chang J, Brouckaert P, Ayata C, Moskowitz MA, Bloch KD, Huang PL, Buys ES. Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury. Stroke; a Journal of Cerebral Circulation. 41: 1815-9. PMID 20595671 DOI: 10.1161/Strokeaha.109.577635  0.398
2010 Rask-Madsen C, Li Q, Freund B, Feather D, Abramov R, Wu IH, Chen K, Yamamoto-Hiraoka J, Goldenbogen J, Sotiropoulos KB, Clermont A, Geraldes P, Dall'Osso C, Wagers AJ, Huang PL, et al. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metabolism. 11: 379-89. PMID 20444418 DOI: 10.1016/J.Cmet.2010.03.013  0.342
2010 Daumerie G, Bridges L, Yancey S, Davis W, Huang P, Loscalzo J, Pointer MA. The effect of salt on renal damage in eNOS-deficient mice. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 33: 170-6. PMID 19960018 DOI: 10.1038/Hr.2009.197  0.38
2010 Huang P. HDAC5: Going with the flow Blood. 115: 2728-2829. DOI: 10.1182/Blood-2010-01-263681  0.332
2009 Schleicher M, Yu J, Murata T, Derakhshan B, Atochin D, Qian L, Kashiwagi S, Di Lorenzo A, Harrison KD, Huang PL, Sessa WC. The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo Science Signaling. 2: ra41. PMID 19654415 DOI: 10.1126/Scisignal.2000343  0.412
2009 Ponnuswamy P, Ostermeier E, Schröttle A, Chen J, Huang PL, Ertl G, Nieswandt B, Kuhlencordt PJ. Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase American Journal of Pathology. 174: 2400-2410. PMID 19465644 DOI: 10.2353/Ajpath.2009.080730  0.356
2009 Schödel J, Padmapriya P, Marx A, Huang PL, Ertl G, Kuhlencordt PJ. Expression of neuronal nitric oxide synthase splice variants in atherosclerotic plaques of apoE knockout mice Atherosclerosis. 206: 383-389. PMID 19358992 DOI: 10.1016/J.Atherosclerosis.2009.02.033  0.388
2009 Kuhlencordt PJ, Padmapriya P, Rützel S, Schödel J, Hu K, Schäfer A, Huang PL, Ertl G, Bauersachs J. Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS-deficient ApoE ko mice Atherosclerosis. 202: 48-57. PMID 18479686 DOI: 10.1016/J.Atherosclerosis.2008.03.021  0.442
2008 Kim YR, Tejima E, Huang S, Atochin DN, Dai G, Lo EH, Huang PL, Bogdanov A, Rosen BR. In vivo quantification of transvascular water exchange during the acute phase of permanent stroke Magnetic Resonance in Medicine. 60: 813-821. PMID 18816832 DOI: 10.1002/Mrm.21708  0.305
2008 Liu VW, Huang PL. Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice. Cardiovascular Research. 77: 19-29. PMID 17658499 DOI: 10.1016/J.Cardiores.2007.06.024  0.474
2007 Lee SR, Lok J, Rosell A, Kim HY, Murata Y, Atochin D, Huang PL, Wang X, Ayata C, Moskowitz MA, Lo EH. Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia. Neuroscience. 150: 50-7. PMID 17936515 DOI: 10.1016/J.Neuroscience.2007.06.029  0.352
2007 Yamova L, Atochin D, Glazova M, Chernigovskaya E, Huang P. Role of neuronal nitric oxide in the regulation of vasopressin expression and release in response to inhibition of catecholamine synthesis and dehydration Neuroscience Letters. 426: 160-165. PMID 17904738 DOI: 10.1016/J.Neulet.2007.08.066  0.434
2007 Zhang J, Kawashima S, Yokoyama M, Huang P, Hill C. Protective effect of endothelial nitric oxide synthase against induction of chemically-induced diabetes in mice. Nitric Oxide. 17: 69-74. PMID 17658282 DOI: 10.1016/J.Niox.2007.06.001  0.42
2007 Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. The Journal of Clinical Investigation. 117: 1961-7. PMID 17557122 DOI: 10.1172/Jci29877  0.407
2007 Shin HK, Salomone S, Potts EM, Lee SW, Millican E, Noma K, Huang PL, Boas DA, Liao JK, Moskowitz MA, Ayata C. Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 998-1009. PMID 17033691 DOI: 10.1038/Sj.Jcbfm.9600406  0.372
2006 Zhang JH, Kawashima S, Yokoyama M, Huang P, Hill CE. Increased eNOS accounts for changes in connexin expression in renal arterioles during diabetes Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology. 288: 1000-1008. PMID 16892422 DOI: 10.1002/Ar.A.20369  0.363
2006 Kuhlencordt PJ, Hötten S, Schödel J, Rützel S, Hu K, Widder J, Marx A, Huang PL, Ertl G. Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein e knockout mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1539-44. PMID 16627802 DOI: 10.1161/01.Atv.0000223143.88128.19  0.417
2006 Hurt KJ, Sezen SF, Champion HC, Crone JK, Palese MA, Huang PL, Sawa A, Luo X, Musicki B, Snyder SH, Burnett AL. Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America. 103: 3440-3. PMID 16488973 DOI: 10.1073/Pnas.0511326103  0.417
2005 Heller EA, Liu E, Tager AM, Sinha S, Roberts JD, Koehn SL, Libby P, Aikawa ER, Chen JQ, Huang P, Freeman MW, Moore KJ, Luster AD, Gerszten RE. Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 112: 578-86. PMID 16043658 DOI: 10.1161/Circulationaha.105.545616  0.349
2005 Kashiwagi S, Izumi Y, Gohongi T, Demou ZN, Xu L, Huang PL, Buerk DG, Munn LL, Jain RK, Fukumura D. NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. The Journal of Clinical Investigation. 115: 1816-27. PMID 15951843 DOI: 10.1172/Jci24015  0.35
2005 Huang PL. Unraveling the links between diabetes, obesity, and cardiovascular disease. Circulation Research. 96: 1129-31. PMID 15947251 DOI: 10.1161/01.Res.0000170705.56583.45  0.346
2005 Asahi M, Huang Z, Thomas S, Yoshimura S, Sumii T, Mori T, Qiu J, Amin-Hanjani S, Huang PL, Liao JK, Lo EH, Moskowitz MA. Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 722-9. PMID 15716855 DOI: 10.1038/Sj.Jcbfm.9600070  0.369
2004 Huang PL. Nitric oxide and cerebral ischemic preconditioning. Cell Calcium. 36: 323-9. PMID 15261488 DOI: 10.1016/J.Ceca.2004.02.007  0.357
2004 Atochin DN, Murciano JC, Gürsoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR. Mouse model of microembolic stroke and reperfusion. Stroke; a Journal of Cerebral Circulation. 35: 2177-82. PMID 15256680 DOI: 10.1161/01.Str.0000137412.35700.0E  0.357
2004 Hagendoorn J, Padera TP, Kashiwagi S, Isaka N, Noda F, Lin MI, Huang PL, Sessa WC, Fukumura D, Jain RK. Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics. Circulation Research. 95: 204-9. PMID 15192027 DOI: 10.1161/01.Res.0000135549.72828.24  0.405
2004 Kuhlencordt PJ, Rosel E, Gerszten RE, Morales-Ruiz M, Dombkowski D, Atkinson WJ, Han F, Preffer F, Rosenzweig A, Sessa WC, Gimbrone MA, Ertl G, Huang PL. Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells. American Journal of Physiology. Cell Physiology. 286: C1195-202. PMID 15075219 DOI: 10.1152/Ajpcell.00546.2002  0.362
2003 Huang PL. Endothelial nitric oxide synthase and endothelial dysfunction. Current Hypertension Reports. 5: 473-80. PMID 14594566 DOI: 10.1007/S11906-003-0055-4  0.359
2003 Al-Shabrawey M, El-Remessy A, Gu X, Brooks SS, Hamed MS, Huang P, Caldwell RB. Normal vascular development in mice deficient in endothelial NO synthase: possible role of neuronal NO synthase. Molecular Vision. 9: 549-58. PMID 14551528  0.303
2003 Atochin DN, Demchenko IT, Astern J, Boso AE, Piantadosi CA, Huang PL. Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 1219-26. PMID 14526232 DOI: 10.1097/01.Wcb.0000089601.87125.E4  0.472
2003 Gyurko R, Boustany G, Huang PL, Kantarci A, Van Dyke TE, Genco CA, Gibson FC. Mice lacking inducible nitric oxide synthase demonstrate impaired killing of Porphyromonas gingivalis. Infection and Immunity. 71: 4917-24. PMID 12933833 DOI: 10.1128/Iai.71.9.4917-4924.2003  0.409
2003 Xu KY, Kuppusamy SP, Wang JQ, Li H, Cui H, Dawson TM, Huang PL, Burnett AL, Kuppusamy P, Becker LC. Nitric oxide protects cardiac sarcolemmal membrane enzyme function and ion active transport against ischemia-induced inactivation. The Journal of Biological Chemistry. 278: 41798-803. PMID 12904295 DOI: 10.1074/Jbc.M306865200  0.309
2003 Demchenko IT, Atochin DN, Boso AE, Astern J, Huang PL, Piantadosi CA. Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases. Neuroscience Letters. 344: 53-6. PMID 12781920 DOI: 10.1016/S0304-3940(03)00432-4  0.441
2003 Park KM, Byun JY, Kramers C, Kim JI, Huang PL, Bonventre JV. Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. The Journal of Biological Chemistry. 278: 27256-66. PMID 12682064 DOI: 10.1074/Jbc.M301778200  0.367
2003 Atochin DN, Clark J, Demchenko IT, Moskowitz MA, Huang PL. Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases. Stroke; a Journal of Cerebral Circulation. 34: 1299-303. PMID 12677017 DOI: 10.1161/01.Str.0000066870.70976.57  0.452
2003 Chen J, Kuhlencordt P, Urano F, Ichinose H, Astern J, Huang PL. Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 97-103. PMID 12524231 DOI: 10.1161/01.Atv.0000040223.74255.5A  0.339
2002 Morishita T, Tsutsui M, Shimokawa H, Horiuchi M, Tanimoto A, Suda O, Tasaki H, Huang PL, Sasaguri Y, Yanagihara N, Nakashima Y. Vasculoprotective roles of neuronal nitric oxide synthase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1994-6. PMID 12397095 DOI: 10.1096/Fj.02-0155Fje  0.422
2002 Suda O, Tsutsui M, Morishita T, Tanimoto A, Horiuchi M, Tasaki H, Huang PL, Sasaguri Y, Yanagihara N, Nakashima Y. Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthase-deficient mice. Circulation. 106: 1729-35. PMID 12270870 DOI: 10.1161/01.Cir.0000029749.16101.44  0.401
2002 Gyurko R, Leupen S, Huang PL. Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility. Endocrinology. 143: 2767-74. PMID 12072412 DOI: 10.1210/Endo.143.7.8921  0.393
2002 Thom SR, Bhopale V, Fisher D, Manevich Y, Huang PL, Buerk DG. Stimulation of nitric oxide synthase in cerebral cortex due to elevated partial pressures of oxygen: an oxidative stress response. Journal of Neurobiology. 51: 85-100. PMID 11932951 DOI: 10.1002/Neu.10044  0.36
2002 Ando A, Yang A, Mori K, Yamada H, Yamada E, Takahashi K, Saikia J, Kim M, Melia M, Fishman M, Huang P, Campochiaro PA. Nitric oxide is proangiogenic in the retina and choroid. Journal of Cellular Physiology. 191: 116-24. PMID 11920687 DOI: 10.1002/Jcp.10083  0.438
2002 Barouch LA, Harrison RW, Skaf MW, Rosas GO, Cappola TP, Kobeissi ZA, Hobai IA, Lemmon CA, Burnett AL, O'Rourke B, Rodriguez ER, Huang PL, Lima JA, Berkowitz DE, Hare JM. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature. 416: 337-9. PMID 11907582 DOI: 10.1038/416337a  0.39
2002 Kubis N, Besnard S, Silvestre JS, Feletou M, Huang PL, Lévy BI, Tedgui A. Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme. Journal of Hypertension. 20: 273-80. PMID 11821712 DOI: 10.1097/00004872-200202000-00017  0.424
2002 Burnett AL, Chang AG, Crone JK, Huang PL, Sezen SE. Noncholinergic penile erection in mice lacking the gene for endothelial nitric oxide synthase. Journal of Andrology. 23: 92-7. PMID 11780929 DOI: 10.1002/J.1939-4640.2002.Tb02601.X  0.445
2001 Koedel U, Paul R, Winkler F, Kastenbauer S, Huang PL, Pfister HW. Lack of endothelial nitric oxide synthase aggravates murine pneumococcal meningitis. Journal of Neuropathology and Experimental Neurology. 60: 1041-1050. PMID 11706934 DOI: 10.1093/Jnen/60.11.1041  0.409
2001 Chen J, Kuhlencordt PJ, Astern J, Gyurko R, Huang PL. Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein E/endothelial nitric oxide synthase double knockout mice Circulation. 104: 2391-2394. PMID 11705813 DOI: 10.1161/Hc4501.099729  0.392
2001 Keilhoff G, Seidel B, Reiser M, Stanarius A, Huang PL, Bogerts B, Wolf G, Bernstein HG. Lack of neuronal NOS has consequences for the expression of POMC and POMC-derived peptides in the mouse pituitary. Acta Histochemica. 103: 397-412. PMID 11700945 DOI: 10.1078/0065-1281-00611  0.377
2001 Sanz MJ, Hickey MJ, Johnston B, McCafferty DM, Raharjo E, Huang PL, Kubes P. Neuronal nitric oxide synthase (NOS) regulates leukocyte-endothelial cell interactions in endothelial NOS deficient mice. British Journal of Pharmacology. 134: 305-312. PMID 11564648 DOI: 10.1038/Sj.Bjp.0704234  0.465
2001 Scherrer-Crosbie M, Ullrich R, Bloch KD, Nakajima H, Nasseri B, Aretz HT, Lindsey ML, Vançon A, Huang PL, Lee RT, Zapol WM, Picard MH. Endothelial Nitric Oxide Synthase Limits Left Ventricular Remodeling After Myocardial Infarction in Mice Circulation. 104: 1286-1291. PMID 11551881 DOI: 10.1161/Hc3601.094298  0.365
2001 Elibol B, Söylemezoglu F, Ünal I, Fujii M, Hirt L, Huang PL, Moskowitz MA, Dalkara T. Nitric oxide is involved in ischemia-induced apoptosis in brain: a study in neuronal nitric oxide synthase null mice. Neuroscience. 105: 79-86. PMID 11483302 DOI: 10.1016/S0306-4522(01)00159-2  0.416
2001 Kuhlencordt PJ, Gyurko R, Han F, Scherrer-Crosbie M, Aretz TH, Hajjar R, Picard MH, Huang PL. Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice Circulation. 104: 448-454. PMID 11468208 DOI: 10.1161/Hc2901.091399  0.413
2001 Kuhlencordt PJ, Chen J, Han F, Astern J, Huang PL. Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice Circulation. 103: 3099-3104. PMID 11425775 DOI: 10.1161/01.Cir.103.25.3099  0.395
2001 Feletou M, Lonchampt M, Coge F, Galizzi J, Bassoullet C, Merial C, Robineau P, Boutin JA, Huang PL, Vanhoutte PM, Canet E. Regulation of murine airway responsiveness by endothelial nitric oxide synthase American Journal of Physiology-Lung Cellular and Molecular Physiology. 281. PMID 11404269 DOI: 10.1152/Ajplung.2001.281.1.L258  0.362
2001 Scalia R, Gooszen ME, Jones SP, Hoffmeyer M, Rimmer DM, Trocha SD, Huang PL, Smith MB, Lefer AM, Lefer DJ. Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice. Circulation. 103: 2598-603. PMID 11382730 DOI: 10.1161/01.Cir.103.21.2598  0.395
2001 Amin-Hanjani S, Stagliano NE, Yamada M, Huang PL, Liao JK, Moskowitz MA. Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice. Stroke. 32: 980-6. PMID 11283400 DOI: 10.1161/01.Str.32.4.980  0.396
2001 Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, Huang PL, Jain RK. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proceedings of the National Academy of Sciences of the United States of America. 98: 2604-9. PMID 11226286 DOI: 10.1073/Pnas.041359198  0.404
2001 Grange RW, Isotani E, Lau KS, Kamm KE, Huang PL, Stull JT. Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles. Physiological Genomics. 5: 35-44. PMID 11161004 DOI: 10.1152/Physiolgenomics.2001.5.1.35  0.302
2000 Putzke J, Seidel B, Huang PL, Wolf G. Differential expression of alternatively spliced isoforms of neuronal nitric oxide synthase (nNOS) and N-methyl-D-aspartate receptors (NMDAR) in knockout mice deficient in nNOSα (nNOSαΔ/Δ mice) Molecular Brain Research. 85: 13-23. PMID 11146102 DOI: 10.1016/S0169-328X(00)00220-5  0.378
2000 Jones SP, Girod WG, Huang PL, Lefer DJ. Myocardial reperfusion injury in neuronal nitric oxide synthase deficient mice Coronary Artery Disease. 11: 593-597. PMID 11107506 DOI: 10.1097/00019501-200012000-00004  0.447
2000 Yogo K, Shimokawa H, Funakoshi H, Kandabashi T, Miyata K, Okamoto S, Egashira K, Huang P, Akaike T, Takeshita A. Different Vasculoprotective Roles of NO Synthase Isoforms in Vascular Lesion Formation in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 20. PMID 11073861 DOI: 10.1161/01.Atv.20.11.E96  0.445
2000 Huang PL. Mouse models of nitric oxide synthase deficiency Journal of the American Society of Nephrology. 11. PMID 11065342  0.358
2000 O'Shaughnessy MC, Polak JM, Afzal F, Hukkanen MVJ, Huang P, MacIntyre I, Buttery LDK. Nitric Oxide Mediates 17β-Estradiol-Stimulated Human and Rodent Osteoblast Proliferation and Differentiation Biochemical and Biophysical Research Communications. 277: 604-610. PMID 11062001 DOI: 10.1006/Bbrc.2000.3714  0.301
2000 Laufs U, Gertz K, Huang P, Nickenig G, Böhm M, Dirnagl U, Endres M. Atorvastatin Upregulates Type III Nitric Oxide Synthase in Thrombocytes, Decreases Platelet Activation, and Protects From Cerebral Ischemia in Normocholesterolemic Mice Stroke. 31: 2442-2449. PMID 11022078 DOI: 10.1161/01.Str.31.10.2442  0.403
2000 Lau KS, Grange RW, Isotani E, Sarelius IH, Kamm KE, Huang PL, Stull JT. nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle. Physiological Genomics. 2: 21-7. PMID 11015578 DOI: 10.1152/Physiolgenomics.2000.2.1.21  0.345
2000 Cauwels A, Molle WV, Janssen B, Everaerdt B, Huang P, Fiers W, Brouckaert P. Protection against TNF-Induced Lethal Shock by Soluble Guanylate Cyclase Inhibition Requires Functional Inducible Nitric Oxide Synthase Immunity. 13: 223-231. PMID 10981965 DOI: 10.1016/S1074-7613(00)00022-4  0.347
2000 Brandes RP, Schmitz-Winnenthal F, Félétou M, Gödecke A, Huang PL, Vanhoutte PM, Fleming I, Busse R. An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice Proceedings of the National Academy of Sciences of the United States of America. 97: 9747-9752. PMID 10944233 DOI: 10.1073/Pnas.97.17.9747  0.429
2000 Gammie SC, Huang PL, Nelson RJ. Maternal aggression in endothelial nitric oxide synthase-deficient mice. Hormones and Behavior. 38: 13-20. PMID 10924282 DOI: 10.1006/Hbeh.2000.1595  0.389
2000 Laufs U, Endres M, Stagliano N, Amin-Hanjani S, Chui DS, Yang SX, Simoncini T, Yamada M, Rabkin E, Allen PG, Huang PL, Böhm M, Schoen FJ, Moskowitz MA, Liao JK. Neuroprotection mediated by changes in the endothelial actin cytoskeleton. The Journal of Clinical Investigation. 106: 15-24. PMID 10880044 DOI: 10.1172/Jci9639  0.435
2000 Kubota I, Han X, Opel DJ, Zhao YY, Baliga R, Huang P, Fishman MC, Shannon RP, Michel T, Kelly RA. Increased susceptibility to development of triggered activity in myocytes from mice with targeted disruption of endothelial nitric oxide synthase. Journal of Molecular and Cellular Cardiology. 32: 1239-48. PMID 10860766 DOI: 10.1006/Jmcc.2000.1158  0.411
2000 Yamada M, Huang Z, Dalkara T, Endres M, Laufs U, Waeber C, Huang PL, Liao JK, Moskowitz MA. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 709-17. PMID 10779015 DOI: 10.1097/00004647-200004000-00008  0.363
2000 Calingasan NY, Huang PL, Chun HS, Fabian A, Gibson GE. Vascular factors are critical in selective neuronal loss in an animal model of impaired oxidative metabolism. Journal of Neuropathology and Experimental Neurology. 59: 207-17. PMID 10744059 DOI: 10.1093/Jnen/59.3.207  0.391
2000 Wu HH, Cork RJ, Huang PL, Shuman DL, Mize RR. Refinement of the ipsilateral retinocollicular projection is disrupted in double endothelial and neuronal nitric oxide synthase gene knockout mice. Brain Research. Developmental Brain Research. 120: 105-11. PMID 10727738 DOI: 10.1016/S0165-3806(99)00145-5  0.374
2000 Gyurko R, Kuhlencordt P, Fishman MC, Huang PL. Modulation of mouse cardiac function in vivo by eNOS and ANP. American Journal of Physiology. Heart and Circulatory Physiology. 278: H971-81. PMID 10710367 DOI: 10.1152/Ajpheart.2000.278.3.H971  0.434
2000 Huang PL. Lessons learned from nitric oxide synthase knockout animals Seminars in Perinatology. 24: 87-90. PMID 10709868 DOI: 10.1016/S0146-0005(00)80064-6  0.481
1999 Rothe F, Huang PL, Wolf G. Ultrastructural localization of neuronal nitric oxide synthase in the laterodorsal tegmental nucleus of wild-type and knockout mice Neuroscience. 94: 193-201. PMID 10613509 DOI: 10.1016/S0306-4522(99)00263-8  0.39
1999 Huang PL. Neuronal and endothelial nitric oxide synthase gene knockout mice Brazilian Journal of Medical and Biological Research. 32: 1353-1359. PMID 10559836  0.399
1999 Kriegsfeld LJ, Demas GE, Huang PL, Burnett AL, Nelson RJ. Ejaculatory abnormalities in mice lacking the gene for endothelial nitric oxide synthase (eNOS-/-). Physiology & Behavior. 67: 561-6. PMID 10549894 DOI: 10.1016/S0031-9384(99)00100-6  0.45
1999 Drazen DL, Klein SL, Burnett AL, Wallach EE, Crone JK, Huang PL, Nelson RJ. Reproductive function in female mice lacking the gene for endothelial nitric oxide synthase. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 3: 366-74. PMID 10534440 DOI: 10.1006/Niox.1999.0251  0.437
1999 Demas GE, Kriegsfeld LJ, Blackshaw S, Huang P, Gammie SC, Nelson RJ, Snyder SH. Elimination of aggressive behavior in male mice lacking endothelial nitric oxide synthase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC30. PMID 10493775 DOI: 10.1523/Jneurosci.19-19-J0004.1999  0.415
1999 Fagan KA, Tyler RC, Sato K, Fouty BW, Morris KG, Huang PL, McMurtry IF, Rodman DM. Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation. The American Journal of Physiology. 277: L472-8. PMID 10484454 DOI: 10.1152/Ajplung.1999.277.3.L472  0.42
1999 Zhang L, Fishman MC, Huang PL. Estrogen mediates the protective effects of pregnancy and chorionic gonadotropin in a mouse model of vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2059-65. PMID 10479646 DOI: 10.1161/01.Atv.19.9.2059  0.34
1999 Stagliano NE, Pérez-Pinzón MA, Moskowitz MA, Huang PL. Focal ischemic preconditioning induces rapid tolerance to middle cerebral artery occlusion in mice Journal of Cerebral Blood Flow and Metabolism. 19: 757-761. PMID 10413030 DOI: 10.1097/00004647-199907000-00005  0.329
1999 Freedman JE, Sauter R, Battinelli EM, Ault K, Knowles C, Huang PL, Loscalzo J. Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circulation Research. 84: 1416-21. PMID 10381894 DOI: 10.1161/01.Res.84.12.1416  0.354
1999 Lefer DJ, Jones SP, Girod WG, Baines A, Grisham MB, Cockrell AS, Huang PL, Scalia R. Leukocyte-endothelial cell interactions in nitric oxide synthase- deficient mice American Journal of Physiology - Heart and Circulatory Physiology. 276: H1943-H1950. PMID 10362674 DOI: 10.1152/Ajpheart.1999.276.6.H1943  0.403
1999 Facchinetti F, Sasaki M, Cutting FB, Zhai P, MacDonald JE, Reif D, Beal MF, Huang PL, Dawson TM, Gurney ME, Dawson VL. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis. Neuroscience. 90: 1483-92. PMID 10338314 DOI: 10.1016/S0306-4522(98)00492-8  0.413
1999 De Sanctis GT, MacLean JA, Hamada K, Mehta S, Scott JA, Jiao A, Yandava CN, Kobzik L, Wolyniec WW, Fabian AJ, Venugopal CS, Grasemann H, Huang PL, Drazen JM. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. The Journal of Experimental Medicine. 189: 1621-30. PMID 10330441 DOI: 10.1084/Jem.189.10.1621  0.386
1999 Jones SP, Girod WG, Palazzo AJ, Granger DN, Grisham MB, Jourd'heuil D, Huang PL, Lefer DJ. Myocardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase American Journal of Physiology - Heart and Circulatory Physiology. 276. PMID 10330240 DOI: 10.1152/Ajpheart.1999.276.5.H1567  0.398
1999 Chataigneau T, Félétou M, Huang PL, Fishman MC, Duhault J, Vanhoutte PM. Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. British Journal of Pharmacology. 126: 219-26. PMID 10051139 DOI: 10.1038/Sj.Bjp.0702300  0.408
1999 Browne SE, Ayata C, Huang PL, Moskowitz MA, Beal MF. The cerebral metabolic consequences of nitric oxide synthase deficiency: glucose utilization in endothelial and neuronal nitric oxide synthase null mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 144-8. PMID 10027769 DOI: 10.1097/00004647-199902000-00005  0.46
1999 Fagan KA, Fouty BW, Tyler RC, Morris KG, Hepler LK, Sato K, LeCras TD, Abman SH, Weinberger HD, Huang PL, McMurtry IF, Rodman DM. The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia. The Journal of Clinical Investigation. 103: 291-9. PMID 9916141 DOI: 10.1172/Jci3862  0.417
1998 Meng W, Ayata C, Waeber C, Huang PL, Moskowitz MA. Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice. American Journal of Physiology. Heart and Circulatory Physiology. 274: H411-H415. PMID 29586087 DOI: 10.1152/ajpheart.1998.274.2.H411  0.318
1998 Huang PL, Lo EH. Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals Progress in Brain Research. 118: 13-25. PMID 9932431 DOI: 10.1016/S0079-6123(08)63197-0  0.381
1998 Itzhak Y, Ali SF, Martin JL, Black MD, Huang PL. Resistance of neuronal nitric oxide synthase-deficient mice to cocaine-induced locomotor sensitization. Psychopharmacology. 140: 378-86. PMID 9877018 DOI: 10.1007/S002130050779  0.322
1998 Huang PL. Disruption of the endothelial nitric oxide synthase gene: Effect on vascular response to injury American Journal of Cardiology. 82. PMID 9860362 DOI: 10.1016/S0002-9149(98)00679-1  0.413
1998 Itzhak Y, Martin JL, Black MD, Huang PL. The role of neuronal nitric oxide synthase in cocaine-induced conditioned place preference. Neuroreport. 9: 2485-8. PMID 9721919 DOI: 10.1097/00001756-199808030-00011  0.314
1998 Kano T, Shimizu-Sasamata M, Huang PL, Moskowitz MA, Lo EH. Effects of nitric oxide synthase gene knockout on neurotransmitter release in vivo. Neuroscience. 86: 695-9. PMID 9692709 DOI: 10.1016/S0306-4522(98)00179-1  0.419
1998 Kline DD, Yang T, Huang PL, Prabhakar NR. Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase. The Journal of Physiology. 511: 273-87. PMID 9679181 DOI: 10.1111/J.1469-7793.1998.273Bi.X  0.41
1998 Endres M, Laufs U, Huang Z, Nakamura T, Huang P, Moskowitz MA, Liao JK. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 95: 8880-5. PMID 9671773 DOI: 10.1073/Pnas.95.15.8880  0.386
1998 Endres M, Scott G, Namura S, Salzman AL, Huang PL, Moskowitz MA, Szabó C. Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion Neuroscience Letters. 248: 41-44. PMID 9665659 DOI: 10.1016/S0304-3940(98)00224-9  0.379
1998 Thorin E, Huang PL, Fishman MC, Bevan JA. Nitric oxide inhibits alpha2-adrenoceptor-mediated endothelium-dependent vasodilation. Circulation Research. 82: 1323-9. PMID 9648729 DOI: 10.1161/01.Res.82.12.1323  0.338
1998 Han X, Kubota I, Feron O, Opel DJ, Arstall MA, Zhao YY, Huang P, Fishman MC, Michel T, Kelly RA. Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 95: 6510-5. PMID 9600997 DOI: 10.1073/Pnas.95.11.6510  0.416
1998 Moroi M, Zhang L, Yasuda T, Virmani R, Gold HK, Fishman MC, Huang PL. Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice. The Journal of Clinical Investigation. 101: 1225-32. PMID 9502763 DOI: 10.1172/Jci1293  0.377
1998 Meng W, Ayata C, Waeber C, Huang PL, Moskowitz MA. Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice American Journal of Physiology - Heart and Circulatory Physiology. 274. PMID 9486242 DOI: 10.1152/Ajpheart.1998.274.2.H411  0.43
1998 Shimizu-Sasamata M, Bosque-Hamilton P, Huang PL, Moskowitz MA, Lo EH. Attenuated Neurotransmitter Release and Spreading Depression-Like Depolarizations after Focal Ischemia in Mutant Mice with Disrupted Type I Nitric Oxide Synthase Gene The Journal of Neuroscience. 18: 9564-9571. DOI: 10.1523/Jneurosci.18-22-09564.1998  0.417
1998 Laufs U, Endres M, Huang PL, Moskowitz MA, Liao JK. HMG-CoA reductase inhibitors reduce cerebral infarct size by upregulating endothelial nitric oxide synthase Journal of the American College of Cardiology. 31: 2. DOI: 10.1016/S0735-1097(98)80675-X  0.379
1997 Hara H, Ayata G, Huang PL, Moskowitz MA. Alteration of protein kinase C activity after transient focal cerebral ischemia in mice using in vitro [3 H]phorbol-12,13-dibutyrate binding autoradiography Brain Research. 774: 69-76. PMID 9452194 DOI: 10.1016/S0006-8993(97)81689-7  0.356
1997 De Sanctis GT, Mehta S, Kobzik L, Yandava C, Jiao A, Huang PL, Drazen JM. Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice. The American Journal of Physiology. 273: L883-8. PMID 9357865 DOI: 10.1152/Ajplung.1997.273.4.L883  0.384
1997 Matthews RT, Beal MF, Fallon J, Fedorchak K, Huang PL, Fishman MC, Hyman BT. MPP+ induced substantia nigra degeneration is attenuated in nNOS knockout mice. Neurobiology of Disease. 4: 114-21. PMID 9331901 DOI: 10.1006/Nbdi.1997.0141  0.43
1997 Ayata C, Ayata G, Hara H, Matthews RT, Beal MF, Ferrante RJ, Endres M, Kim A, Christie RH, Waeber C, Huang PL, Hyman BT, Moskowitz MA. Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6908-17. PMID 9278526 DOI: 10.1523/Jneurosci.17-18-06908.1997  0.371
1997 Hara H, Ayata C, Huang PL, Waeber C, Ayata G, Fujii M, Moskowitz MA. [3H]L-NG-nitroarginine binding after transient focal ischemia and NMDA-induced excitotoxicity in type I and type III nitric oxide synthase null mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 515-26. PMID 9183289 DOI: 10.1097/00004647-199705000-00005  0.338
1997 Okamoto H, Meng W, Ma J, Ayata C, Roman RJ, Bosnjak ZJ, Kampine JP, Huang PL, Moskowitz MA, Hudetz AG. Isoflurane-induced cerebral hyperemia in neuronal nitric oxide synthase gene deficient mice Anesthesiology. 86: 875-884. PMID 9105232 DOI: 10.1097/00000542-199704000-00018  0.42
1997 Huang Z, Chen K, Huang PL, Finklestein SP, Moskowitz MA. bFGF ameliorates focal ischemic injury by blood flow-independent mechanisms in eNOS mutant mice. The American Journal of Physiology. 272: H1401-5. PMID 9087617 DOI: 10.1152/Ajpheart.1997.272.3.H1401  0.443
1997 Harding P, Sigmon DH, Alfie ME, Huang PL, Fishman MC, Beierwaltes WH, Carretero OA. Cyclooxygenase-2 mediates increased renal renin content induced by low- sodium diet Hypertension. 29: 297-302. PMID 9039118 DOI: 10.1161/01.Hyp.29.1.297  0.356
1997 Zaharchuk G, Hara H, Huang PL, Fishman MC, Moskowitz MA, Jenkins BG, Rosen BR. Neuronal nitric oxide synthase mutant mice show smaller infarcts and attenuated apparent diffusion coefficient changes in the peri-infarct zone during focal cerebral ischemia Magnetic Resonance in Medicine. 37: 170-175. PMID 9001139 DOI: 10.1002/Mrm.1910370204  0.414
1997 Gyurko R, Fishman MC, Huang PL. ENHANCED SYSTOLIC CONTRACTILITY AND PRESERVED DIASTOLIC RELAXATION IN MICE DEFICIENT IN ENDOTHELIAL NITRIC OXIDE SYNTHASE Japanese Journal of Pharmacology. 75: 10. DOI: 10.1016/s0021-5198(19)41464-9  0.348
1996 Son H, Hawkins RD, Martin K, Kiebler M, Huang PL, Fishman MC, Kandel ER. Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell. 87: 1015-23. PMID 8978606 DOI: 10.1016/S0092-8674(00)81796-1  0.403
1996 Hara H, Huang PL, Panahian N, Fishman MC, Moskowitz MA. Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 605-11. PMID 8964799 DOI: 10.1097/00004647-199607000-00010  0.427
1996 Ayata C, Ma J, Meng W, Huang P, Moskowitz MA. L-NA-sensitive rCBF augmentation during vibrissal stimulation in type III nitric oxide synthase mutant mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 539-41. PMID 8964791 DOI: 10.1097/00004647-199607000-00002  0.392
1996 Hara H, Waeber C, Huang PL, Fujii M, Fishman MC, Moskowitz MA. Brain distribution of nitric oxide synthase in neuronal or endothelial nitric oxide synthase mutant mice using [3H]L-N(G)-nitro-arginine autoradiography Neuroscience. 75: 881-890. PMID 8951881 DOI: 10.1016/0306-4522(96)00313-2  0.404
1996 Ma J, Meng W, Ayata C, Huang PL, Fishman MC, Moskowitz MA. L-NNA-sensitive regional cerebral blood flow augmentation during hypercapnia in type III NOS mutant mice. The American Journal of Physiology. 271: H1717-9. PMID 8897969 DOI: 10.1152/Ajpheart.1996.271.4.H1717  0.387
1996 Meng W, Ma J, Ayata C, Hara H, Huang PL, Fishman MC, Moskowitz MA. ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. The American Journal of Physiology. 271: H1145-50. PMID 8853353 DOI: 10.1152/Ajpheart.1996.271.3.H1145  0.436
1996 Huang Z, Huang PL, Ma J, Meng W, Ayata C, Fishman MC, Moskowitz MA. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 981-7. PMID 8784243 DOI: 10.1097/00004647-199609000-00023  0.475
1996 Ma J, Ayata C, Huang PL, Fishman MC, Moskowitz MA. Regional cerebral blood flow response to vibrissal stimulation in mice lacking type I NOS gene expression. The American Journal of Physiology. 270: H1085-90. PMID 8780207 DOI: 10.1152/Ajpheart.1996.270.3.H1085  0.416
1996 Panahian N, Yoshida T, Huang PL, Hedley-Whyte ET, Dalkara T, Fishman MC, Moskowitz MA. Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase. Neuroscience. 72: 343-54. PMID 8737405 DOI: 10.1016/0306-4522(95)00563-3  0.451
1996 Lo EH, Hara H, Rogowska J, Trocha M, Pierce AR, Huang PL, Fishman MC, Wolf GL, Moskowitz MA. Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression. Stroke; a Journal of Cerebral Circulation. 27: 1381-5. PMID 8711806 DOI: 10.1161/01.Str.27.8.1381  0.456
1996 Mashimo H, He XD, Huang PL, Fishman MC, Goyal RK. Neuronal constitutive nitric oxide synthase is involved in murine enteric inhibitory neurotransmission. The Journal of Clinical Investigation. 98: 8-13. PMID 8690808 DOI: 10.1172/Jci118781  0.425
1996 Schulz JB, Huang PL, Matthews RT, Passov D, Fishman MC, Beal MF. Striatal malonate lesions are attenuated in neuronal nitric oxide synthase knockout mice. Journal of Neurochemistry. 67: 430-3. PMID 8667023 DOI: 10.1046/J.1471-4159.1996.67010430.X  0.448
1996 Carpenter C, Honkanen AA, Mashimo H, Goss KA, Huang P, Fishman MC, Asaad M, Dorso CR, Cheung H. Renal abnormalities in mutant mice. Nature. 380: 292. PMID 8598926 DOI: 10.1038/380292A0  0.32
1996 Dawson V, Kizushi V, Huang P, Snyder S, Dawson T. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice The Journal of Neuroscience. 16: 2479-2487. DOI: 10.1523/Jneurosci.16-08-02479.1996  0.312
1995 Crosby G, Marota JJA, Huang PL. Intact nociception-induced neuroplasticity in transgenic mice deficient in neuronal nitric oxide synthase Neuroscience. 69: 1013-1017. PMID 8848090 DOI: 10.1016/0306-4522(95)00395-Y  0.44
1995 Darius S, Wolf G, Huang PL, Fishman MC. Localization of NADPH-diaphorase/nitric oxide synthase in the rat retina: an electron microscopic study Brain Research. 690: 231-235. PMID 8535841 DOI: 10.1016/0006-8993(95)00559-9  0.366
1995 Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature. 377: 239-42. PMID 7545787 DOI: 10.1038/377239A0  0.444
1995 Irikura K, Huang PL, Ma J, Lee WS, Dalkara T, Fishman MC, Dawson TM, Snyder SH, Moskowitz MA. Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. Proceedings of the National Academy of Sciences of the United States of America. 92: 6823-7. PMID 7542777 DOI: 10.1073/Pnas.92.15.6823  0.452
1995 Ichinose F, Huang PL, Zapol WM. Effects of targeted neuronal nitric oxide synthase gene disruption and nitro(G)-L-arginine methylester on the threshold for isoflurane anesthesia Anesthesiology. 83: 101-108. PMID 7541615 DOI: 10.1097/00000542-199507000-00013  0.435
1995 Nelson RJ, Demas GE, Huang PL, Fishman MC, Dawson VL, Dawson TM, Snyder SH. Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature. 378: 383-6. PMID 7477374 DOI: 10.1038/378383A0  0.451
1995 Huang PL, Irikura K, Ma J, Lee WS, Dalkara T, Fishman MC, Moskowitz MA. 963-22 Gene Knockouts for Neuronal Nitric Oxide Synthase Demonstrate Compensatory Mechanisms of Cerebrovascular Blood Flow Regulation Journal of the American College of Cardiology. 25. DOI: 10.1016/0735-1097(95)92370-K  0.455
1994 Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase Science. 265: 1883-1885. PMID 7522345 DOI: 10.1126/Science.7522345  0.448
1994 O'Dell TJ, Huang PL, Dawson TM, Dinerman JL, Snyder SH, Kandel ER, Fishman MC. Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science (New York, N.Y.). 265: 542-6. PMID 7518615 DOI: 10.1126/Science.7518615  0.396
1994 Crosby G, Marota JJA, Root C, Abe K, Huang P. Noxious Stimulation-induced Neuroplasticity Is Not Altered in Transgenic Mice Deficient in Neuronal Nitric Oxide Synthase Anesthesiology. 81. DOI: 10.1097/00000542-199409001-00803  0.422
1993 Huang PL, Dawson TM, Bredt DS, Snyder SH, Fishman MC. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 75: 1273-86. PMID 7505721 DOI: 10.1016/0092-8674(93)90615-W  0.394
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