Michael A. Gimbrone, Jr., M.D. - Publications

Institution:
Harvard University, Cambridge, MA, United States
Area:
Cell Biology, Pathology, Medicine and Surgery
Website:
https://gimbrone.bwh.harvard.edu/biosketch.html

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Gimbrone MA, García-Cardeña G. Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis. Circulation Research. 118: 620-36. PMID 26892962 DOI: 10.1161/Circresaha.115.306301  0.447
2013 Gimbrone MA, García-Cardeña G. Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosis. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 22: 9-15. PMID 22818581 DOI: 10.1016/J.Carpath.2012.06.006  0.468
2007 Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA. Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2. Circulation Research. 101: 723-33. PMID 17673673 DOI: 10.1161/Circresaha.107.152942  0.456
2006 García-Cardeña G, Gimbrone MA. Biomechanical modulation of endothelial phenotype: implications for health and disease. Handbook of Experimental Pharmacology. 176: 79-95. PMID 16999225 DOI: 10.1007/3-540-36028-X_3  0.486
2006 Parmar KM, Larman HB, Dai G, Zhang Y, Wang ET, Moorthy SN, Kratz JR, Lin Z, Jain MK, Gimbrone MA, García-Cardeña G. Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. The Journal of Clinical Investigation. 116: 49-58. PMID 16341264 DOI: 10.1172/Jci24787  0.46
2005 Parmar KM, Nambudiri V, Dai G, Larman HB, Gimbrone MA, García-Cardeña G. Statins exert endothelial atheroprotective effects via the KLF2 transcription factor. The Journal of Biological Chemistry. 280: 26714-9. PMID 15878865 DOI: 10.1074/Jbc.C500144200  0.379
2005 Lin Z, Kumar A, SenBanerjee S, Staniszewski K, Parmar K, Vaughan DE, Gimbrone MA, Balasubramanian V, García-Cardeña G, Jain MK. Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function. Circulation Research. 96: e48-57. PMID 15718498 DOI: 10.1161/01.Res.0000159707.05637.A1  0.462
2004 Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, García-Cardeña G, Gimbrone MA. Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proceedings of the National Academy of Sciences of the United States of America. 101: 14871-6. PMID 15466704 DOI: 10.1073/Pnas.0406073101  0.456
2004 SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA, García-Cardeña G, Jain MK. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. The Journal of Experimental Medicine. 199: 1305-15. PMID 15136591 DOI: 10.1084/Jem.20031132  0.531
2004 Kuhlencordt PJ, Rosel E, Gerszten RE, Morales-Ruiz M, Dombkowski D, Atkinson WJ, Han F, Preffer F, Rosenzweig A, Sessa WC, Gimbrone MA, Ertl G, Huang PL. Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells. American Journal of Physiology. Cell Physiology. 286: C1195-202. PMID 15075219 DOI: 10.1152/Ajpcell.00546.2002  0.492
2004 Kwei S, Stavrakis G, Takahas M, Taylor G, Folkman MJ, Gimbrone MA, García-Cardeña G. Early adaptive responses of the vascular wall during venous arterialization in mice. The American Journal of Pathology. 164: 81-9. PMID 14695322 DOI: 10.1016/S0002-9440(10)63099-4  0.36
2004 Dai G, Kaazempur-Mofrad MR, Kamm RD, Zhang Y, Vaughn S, Garcia-Cardena G, Gimbrone MA. DISTINCT ENDOTHELIAL PHENOTYPES EVOKED BY ARTERIAL WAVEFORMS DERIVED FROM ATHEROSCLEROSIS-PRONE AND ATHEROSCLEROSIS-PROTECTED REGIONS OF THE HUMAN VASCULATURE Cardiovascular Pathology. 13: 26. DOI: 10.1016/J.Carpath.2004.03.070  0.385
2003 Kiely JM, Hu Y, García-Cardeña G, Gimbrone MA. Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma. Journal of Immunology (Baltimore, Md. : 1950). 171: 3216-24. PMID 12960351 DOI: 10.4049/Jimmunol.171.6.3216  0.326
2003 Lim YC, Garcia-Cardena G, Allport JR, Zervoglos M, Connolly AJ, Gimbrone MA, Luscinskas FW. Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment. The American Journal of Pathology. 162: 1591-601. PMID 12707043 DOI: 10.1016/S0002-9440(10)64293-9  0.417
2002 Takayama K, García-Cardena G, Sukhova GK, Comander J, Gimbrone MA, Libby P. Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor. The Journal of Biological Chemistry. 277: 44147-54. PMID 12215436 DOI: 10.1074/Jbc.M204810200  0.303
2002 Blackman BR, García-Cardeña G, Gimbrone MA. A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress waveforms. Journal of Biomechanical Engineering. 124: 397-407. PMID 12188206 DOI: 10.1115/1.1486468  0.483
2002 Ochi H, Masuda J, Gimbrone MA. Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity. European Journal of Immunology. 32: 1821-31. PMID 12115600 DOI: 10.1002/1521-4141(200207)32:7<1821::Aid-Immu1821>3.0.Co;2-A  0.363
2002 Meiler SE, Hung RR, Gerszten RE, Gianetti J, Li L, Matsui T, Gimbrone MA, Rosenzweig A. Endothelial IKK beta signaling is required for monocyte adhesion under laminar flow conditions. Journal of Molecular and Cellular Cardiology. 34: 349-59. PMID 11945026 DOI: 10.1006/Jmcc.2001.1519  0.394
2001 Hu Y, Szente B, Kiely J, Gimbrone MA. Molecular Events in Transmembrane Signaling via E-selectin SHP2 ASSOCIATION, ADAPTOR PROTEIN COMPLEX FORMATION AND ERK1/2 ACTIVATION Journal of Biological Chemistry. 276: 48549-48553. PMID 11602579 DOI: 10.1074/Jbc.M105513200  0.349
2001 Yoshida M, Sawada T, Ishii H, Gerszten RE, Rosenzweig A, Gimbrone MA, Yasukochi Y, Numano F. HMG-CoA Reductase Inhibitor Modulates Monocyte–Endothelial Cell Interaction Under Physiological Flow Conditions In Vitro: Involvement of Rho GTPase–Dependent Mechanism Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1165-1171. PMID 11451746 DOI: 10.1161/Hq0701.092143  0.444
2001 García-Cardeña G, Comander J, Anderson KR, Blackman BR, Gimbrone MA. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype Proceedings of the National Academy of Sciences of the United States of America. 98: 4478-4485. PMID 11296290 DOI: 10.1073/Pnas.071052598  0.517
2001 Shin D, Garcia-Cardena G, Hayashi S, Gerety S, Asahara T, Stavrakis G, Isner J, Folkman J, Gimbrone MA, Anderson DJ. Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Developmental Biology. 230: 139-50. PMID 11161568 DOI: 10.1006/Dbio.2000.9957  0.384
2000 DiChiara MR, Kiely JM, Gimbrone MA, Lee M, Perrella MA, Topper JN. Inhibition of E-Selectin Gene Expression by Transforming Growth Factor β in Endothelial Cells Involves Coactivator Integration of Smad and Nuclear Factor κB–Mediated Signals Journal of Experimental Medicine. 192: 695-704. PMID 10974035 DOI: 10.1084/Jem.192.5.695  0.361
2000 Hu Y, Kiely J, Szente BE, Rosenzweig A, Gimbrone MA. E-selectin-dependent signaling via the mitogen-activated protein kinase pathway in vascular endothelial cells. Journal of Immunology. 165: 2142-2148. PMID 10925300 DOI: 10.4049/Jimmunol.165.4.2142  0.401
2000 Ishii H, Yoshida M, Rosenzweig A, Gimbrone MA, Yasukochi Y, Numano F. Adenoviral transduction of human E-selectin into isolated, perfused, rat aortic segments: an ex vivo model for studying leukocyte-endothelial interactions. Journal of Leukocyte Biology. 68: 687-692. DOI: 10.1189/Jlb.68.5.687  0.417
2000 Gimbrone MA. Hemodynamic forces, endothelial gene regulation and atherogenesis: an overview Atherosclerosis. 151: 162. DOI: 10.1016/S0021-9150(00)80735-2  0.381
2000 Yoshida M, Gerszten RE, Rosenzweig A, Gimbrone MA, Yasukochi Y, Numano F. HMG-CoA reductase inhibitor reduces monocyte adhesion to vascular endothelium under physiological flow conditions Atherosclerosis. 151: 42. DOI: 10.1016/S0021-9150(00)80189-6  0.444
1999 Nagel T, Resnick N, Dewey CF, Gimbrone MA. Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1825-34. PMID 10446060 DOI: 10.1161/01.Atv.19.8.1825  0.733
1999 Gimbrone MA. Vascular endothelium, hemodynamic forces, and atherogenesis. American Journal of Pathology. 155: 1-5. PMID 10393828 DOI: 10.1016/S0002-9440(10)65090-0  0.359
1999 Gimbrone MA, Anderson KR, Topper JN, Langille BL, Clowes AW, Bercel S, Davies MG, Stenmark KR, Frid MG, Weiser-Evans MC, Aldashev AA, Nemenoff RA, Majesky MW, Landerholm TE, Lu J, ... ... Gimbrone MA, et al. Special communicationthe critical role of mechanical forces in blood vessel development, physiology and pathology Journal of Vascular Surgery. 29: 1104-51. PMID 10359945 DOI: 10.1016/S0741-5214(99)70252-1  0.673
1999 Gerszten RE, Garcia-Zepeda EA, Lim Y, Yoshida M, Ding HA, Gimbrone MA, Luster AD, Luscinskas FW, Rosenzweig A. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature. 398: 718-723. PMID 10227295 DOI: 10.1038/19546  0.386
1999 Kiely J, Luscinskas FW, Gimbrone MA. Leukocyte-Endothelial Monolayer Adhesion Assay (Static Conditions) Methods of Molecular Biology. 96: 131-136. PMID 10098130 DOI: 10.1385/1-59259-258-9:131  0.423
1999 Topper JN, Gimbrone MA. Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype Molecular Medicine Today. 5: 40-46. PMID 10088131 DOI: 10.1016/S1357-4310(98)01372-0  0.524
1999 Brown JD, DiChiara MR, Anderson KR, Gimbrone MA, Topper JN. MEKK-1, a component of the stress (stress-activated protein kinase/c- jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells Journal of Biological Chemistry. 274: 8797-8805. PMID 10085121 DOI: 10.1074/Jbc.274.13.8797  0.336
1999 Gimbrone M. Endothelial dysfunction, hemodynamic forces, and atherosclerosis Thrombosis and Haemostasis. 82: 722-726. DOI: 10.1055/S-0037-1615903  0.48
1999 Gimbrone MA, Anderson KR, Topper JN. Vascular Endothelium: An Integrator of Humoral and Biomechanical Stimuli in the Cardiovascular System Journal of Vascular and Interventional Radiology. 10: 941-943. DOI: 10.1016/S1051-0443(99)70143-0  0.379
1999 Gimbrone MA. Vascular endothelium, hemodynamic forces and atherogenesis Atherosclerosis. 144: 143. DOI: 10.1016/S0021-9150(99)80552-8  0.407
1998 Topper JN, Cai J, Stavrakis G, Anderson KR, Woolf EA, Sampson BA, Schoen FJ, Falb D, Gimbrone MA. Human prostaglandin transporter gene (hPGT) is regulated by fluid mechanical stimuli in cultured endothelial cells and expressed in vascular endothelium in vivo. Circulation. 98: 2396-403. PMID 9832484 DOI: 10.1161/01.Cir.98.22.2396  0.513
1998 Fishman AP, Fishman MC, Freeman BA, Gimbrone MA, Rabinovitch M, Robinson D, Gail DB. Mechanisms of proliferative and obliterative vascular diseases. Insights from the pulmonary and systemic circulations. NHLBI Workshop summary. American Journal of Respiratory and Critical Care Medicine. 158: 670-4. PMID 9700149 DOI: 10.1164/Ajrccm.158.2.9803084  0.327
1998 Topper JN, DiChiara MR, Brown JD, Williams AJ, Falb D, Collins T, Gimbrone MA. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells Proceedings of the National Academy of Sciences of the United States of America. 95: 9506-9511. PMID 9689110 DOI: 10.1073/Pnas.95.16.9506  0.323
1998 Gerszten RE, Lim YC, Ding HT, Snapp K, Kansas G, Dichek DA, Cabañas C, Sánchez-Madrid F, Gimbrone MA, Rosenzweig A, Luscinskas FW. Adhesion of Monocytes to Vascular Cell Adhesion Molecule-1–Transduced Human Endothelial Cells: Implications for Atherogenesis Circulation Research. 82: 871-878. PMID 9580553 DOI: 10.1161/01.Res.82.8.871  0.499
1998 Sumpio BE, Du W, Galagher G, Wang X, Khachigian LM, Collins T, Gimbrone MA, Resnick N. Regulation of PDGF-B in Endothelial Cells Exposed to Cyclic Strain Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 349-355. PMID 9514402 DOI: 10.1161/01.Atv.18.3.349  0.318
1997 Tardy Y, Resnick N, Nagel T, Gimbrone MA, Dewey CF. Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 3102-6. PMID 9409299 DOI: 10.1161/01.Atv.17.11.3102  0.752
1997 Resnick N, Yahav H, Khachigian LM, Collins T, Anderson KR, Dewey FC, Gimbrone MA. Endothelial gene regulation by laminar shear stress. Advances in Experimental Medicine and Biology. 430: 155-64. PMID 9330726 DOI: 10.1007/978-1-4615-5959-7_13  0.498
1997 Topper JN, Cai J, Qiu Y, Anderson KR, Xu YY, Deeds JD, Feeley R, Gimeno CJ, Woolf EA, Tayber O, Mays GG, Sampson BA, Schoen FJ, Gimbrone MA, Falb D. Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 94: 9314-9. PMID 9256479 DOI: 10.1073/Pnas.94.17.9314  0.496
1997 Spragg DD, Alford DR, Greferath R, Larsen CE, Lee KD, Gurtner GC, Cybulsky MI, Tosi PF, Nicolau C, Gimbrone MA. Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system. Proceedings of the National Academy of Sciences of the United States of America. 94: 8795-800. PMID 9238057 DOI: 10.1073/Pnas.94.16.8795  0.418
1997 Gimbrone MA, Resnick N, Nagel T, Khachigian LM, Collins T, Topper JN. Hemodynamics, Endothelial Gene Expression, and Atherogenesisa Annals of the New York Academy of Sciences. 811: 1-11. PMID 9186579 DOI: 10.1111/J.1749-6632.1997.Tb51983.X  0.378
1997 Topper JN, Wasserman SM, Anderson KR, Cai J, Falb D, Gimbrone MA. Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium. The Journal of Clinical Investigation. 99: 2941-9. PMID 9185518 DOI: 10.1172/Jci119489  0.486
1997 Gimbrone MA, Nagel T, Topper JN. Biomechanical activation: an emerging paradigm in endothelial adhesion biology. Journal of Clinical Investigation. 99: 1809-1813. PMID 9109423 DOI: 10.1172/Jci119346  0.426
1997 Gimbrone MA. Regulation of Endothelial Gene Expression By Blood Flow Journal of Vascular and Interventional Radiology. 8: 690-691. DOI: 10.1016/S1051-0443(97)70636-5  0.4
1997 Yoshida M, Chien L-, Rosenzweig A, Yasukochi Y, Numano F, Gimbrone MA. 3.P.238 E-selectin overexpression on human vascular endothelium via adenoviral mediated gene transfer: A novel model for inflammation and atherosclerosis Atherosclerosis. 134: 248. DOI: 10.1016/S0021-9150(97)89313-6  0.362
1996 Gerszten RE, Luscinskas FW, Ding HT, Dichek DA, Stoolman LM, Gimbrone MA, Rosenzweig AR. Adhesion of Memory Lymphocytes to Vascular Cell Adhesion Molecule-1–Transduced Human Vascular Endothelial Cells Under Simulated Physiological Flow Conditions In Vitro Circulation Research. 79: 1205-1215. PMID 8943959 DOI: 10.1161/01.Res.79.6.1205  0.481
1996 Topper JN, Cai J, Falb D, Gimbrone MA. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress Proceedings of the National Academy of Sciences of the United States of America. 93: 10417-10422. PMID 8816815 DOI: 10.1073/Pnas.93.19.10417  0.485
1996 Luscinskas FW, Gimbrone MA. Endothelial-Dependent Mechanisms In Chronic Inflammatory Leukocyte Recruitment Annual Review of Medicine. 47: 413-421. PMID 8712792 DOI: 10.1146/Annurev.Med.47.1.413  0.399
1996 Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA. Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. The Journal of Cell Biology. 133: 445-55. PMID 8609175 DOI: 10.1083/Jcb.133.2.445  0.424
1996 Gerritsen ME, Shen CP, McHugh MC, Atkinson WJ, Kiely JM, Milstone DS, Luscinskas FW, Gimbrone MA. Activation-dependent isolation and culture of murine pulmonary microvascular endothelium. Microcirculation (New York, N.Y. : 1994). 2: 151-63. PMID 7497167 DOI: 10.3109/10739689509146763  0.36
1995 Khachigian LM, Resnick N, Gimbrone MA, Collins T. Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. Journal of Clinical Investigation. 96: 1169-1175. PMID 7635955 DOI: 10.1172/Jci118106  0.481
1995 Resnick N, Gimbrone MA. Hemodynamic forces are complex regulators of endothelial gene expression. The Faseb Journal. 9: 874-882. PMID 7615157 DOI: 10.1096/Fasebj.9.10.7615157  0.523
1995 Kiely J, Cybulsky MI, Luscinskas FW, Gimbrone MA. Immunoselective Targeting of an Anti-Thrombin Agent to the Surface of Cytokine-Activated Vascular Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1211-1218. PMID 7542999 DOI: 10.1161/01.Atv.15.8.1211  0.411
1995 De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA, Shin WS, Liao JK. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. The Journal of Clinical Investigation. 96: 60-8. PMID 7542286 DOI: 10.1172/Jci118074  0.426
1995 De Caterina R, Cybulsky MA, Clinton SK, Gimbrone MA, Libby P. Omega-3 fatty acids and endothelial leukocyte adhesion molecules. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 52: 191-5. PMID 7540306 DOI: 10.1016/0952-3278(95)90021-7  0.381
1995 Gimbrone MA. Vascular endothelium: an integrator of pathophysiologic stimuli in atherosclerosis. American Journal of Cardiology. 75. PMID 7532351 DOI: 10.1016/0002-9149(95)80016-L  0.46
1994 Shen J, Luscinskas FW, Gimbrone MA, Dewey CF. Fluid flow modulates vascular endothelial cytosolic calcium responses to adenine nucleotides. Microcirculation (New York, N.Y. : 1994). 1: 67-78. PMID 8790579 DOI: 10.3109/10739689409148263  0.718
1994 Caterina RD, Cybulsky MI, Clinton SK, Gimbrone MA, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1829-1836. PMID 7524649 DOI: 10.1161/01.Atv.14.11.1829  0.428
1994 Nagel T, Resnick N, Atkinson WJ, Dewey CF, Gimbrone MA. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. The Journal of Clinical Investigation. 94: 885-91. PMID 7518844 DOI: 10.1172/Jci117410  0.754
1994 Luscinskas FW, Kansas GS, Ding H, Pizcueta P, Schleiffenbaum BE, Tedder TF, Gimbrone MA. Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. The Journal of Cell Biology. 125: 1417-27. PMID 7515891 DOI: 10.1083/Jcb.125.6.1417  0.407
1994 Resnick N, Sumpio BE, Gimbrone MA. Endothelial gene regulation by biomechanical forces Atherosclerosis. 109: 344. DOI: 10.1016/0021-9150(94)94376-1  0.369
1993 Shen J, Gimbrone MA, Luscinskas FW, Dewey CF. Regulation of adenine nucleotide concentration at endothelium-fluid interface by viscous shear flow. Biophysical Journal. 64: 1323-30. PMID 8494987 DOI: 10.1016/S0006-3495(93)81498-X  0.711
1993 Li H, Cybulsky MI, Gimbrone MA, Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 197-204. PMID 7678986 DOI: 10.1161/01.Atv.13.2.197  0.434
1992 Westlin WF, Kiely J, Gimbrone MA. Interleukin-8 induces changes in human neutrophil actin conformation and distribution: relationship to inhibition of adhesion to cytokine-activated endothelium. Journal of Leukocyte Biology. 52: 43-51. PMID 1640174 DOI: 10.1002/Jlb.52.1.43  0.343
1992 Shen J, Luscinskas FW, Connolly A, Dewey CF, Gimbrone MA. Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells. The American Journal of Physiology. 262: C384-90. PMID 1539628 DOI: 10.1152/Ajpcell.1992.262.2.C384  0.692
1992 Satcher RL, Bussolari SR, Gimbrone MA, Dewey CF. The distribution of fluid forces on model arterial endothelium using computational fluid dynamics. Journal of Biomechanical Engineering. 114: 309-16. PMID 1522724 DOI: 10.1115/1.2891388  0.723
1992 DePaola N, Gimbrone MA, Davies PF, Dewey CF. Vascular endothelium responds to fluid shear stress gradients Arteriosclerosis and Thrombosis. 12: 1254-1257. PMID 1420084 DOI: 10.1161/01.Atv.12.11.1254  0.78
1992 Kume N, Cybulsky MI, Gimbrone MA. Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. Journal of Clinical Investigation. 90: 1138-1144. PMID 1381720 DOI: 10.1172/Jci115932  0.495
1992 Williams AJ, Atkins RC, Fries JWU, Gimbrone MA, Cybulsky MI, Collins T. Nucleotide sequence of rat vascular cell adhesion molecule-1 cDNA Biochimica Et Biophysica Acta. 1131: 214-216. PMID 1377031 DOI: 10.1016/0167-4781(92)90081-A  0.435
1992 Spertini O, Luscinskas FW, Gimbrone MA, Tedder TF. Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditions. Journal of Experimental Medicine. 175: 1789-1792. PMID 1375271 DOI: 10.1084/Jem.175.6.1789  0.443
1992 Conforti G, Dominguez-Jimenez C, Zanetti A, Gimbrone MA, Cremona O, Marchisio PC, Dejana E. Human endothelial cells express integrin receptors on the luminal aspect of their membrane. Blood. 80: 437-446. DOI: 10.1182/Blood.V80.2.437.Bloodjournal802437  0.322
1991 Cybulsky MI, Gimbrone MA. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 251: 788-791. PMID 1990440 DOI: 10.1126/Science.1990440  0.425
1991 Hechtman DH, Kroll MH, Gimbrone MA, Schafer AI. Platelet interaction with vascular smooth muscle in synthesis of prostacyclin. The American Journal of Physiology. 260: H1544-51. PMID 1903602 DOI: 10.1152/Ajpheart.1991.260.5.H1544  0.314
1991 Bevilacqua M, Butcher E, Furie B, Furie B, Gallatin M, Gimbrone M, Harlan J, Kishimoto K, Lasky L, McEver R, Paulson J, Rosen S, Seed B, Siegelman M, Springer T, et al. Selectins: A family of adhesion receptors Cell. 67: 233-233. PMID 1717161 DOI: 10.1016/0092-8674(91)90174-W  0.318
1991 Cybulsky MI, Fries JW, Williams AJ, Sultan P, Eddy R, Byers M, Shows T, Gimbrone MA, Collins T. Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene Proceedings of the National Academy of Sciences of the United States of America. 88: 7859-7863. PMID 1715583 DOI: 10.1073/Pnas.88.17.7859  0.322
1991 Bochner BS, Luscinskas FW, Gimbrone MA, Newman W, Sterbinsky SA, Derse-Anthony CP, Klunk D, Schleimer RP. Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. Journal of Experimental Medicine. 173: 1553-1557. PMID 1709678 DOI: 10.1084/Jem.173.6.1553  0.463
1990 Zavoico GB, Hrbolich JK, Gimbrone MA, Schafer AI. Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester. Journal of Cellular Physiology. 143: 596-605. PMID 2113537 DOI: 10.1002/Jcp.1041430326  0.376
1989 Gimbrone MA, Obin MS, Brock AF, Luis EA, Hass PE, Hébert CA, Yip YK, Leung DW, Lowe DG, Kohr WJ. Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions. Science (New York, N.Y.). 246: 1601-3. PMID 2688092 DOI: 10.1126/Science.2688092  0.431
1989 Takayama H, Kroll M, Gimbrone MA, Schafer AI. Turnover of eicosanoid precursor fatty acids among phospholipid classes and subclasses of cultured human umbilical vein endothelial cells. Biochemical Journal. 258: 427-434. PMID 2495792 DOI: 10.1042/Bj2580427  0.358
1989 Brezinski ME, Gimbrone MA, Nicolaou KC, Serhan CN. Lipoxins stimulate prostacyclin generation by human endothelial cells. Febs Letters. 245: 167-72. PMID 2494071 DOI: 10.1016/0014-5793(89)80214-5  0.391
1989 Bevilacqua MP, Stengelin S, Gimbrone MA, Seed B. Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (New York, N.Y.). 243: 1160-5. PMID 2466335 DOI: 10.1126/Science.2466335  0.452
1989 Rabinowitz SS, Cybulsky MI, Kume N, Gimbrone MA. Endothelial-dependent mechanisms of monocyte adhesion The Journal of Japan Atherosclerosis Society. 16: 83-91. DOI: 10.1007/978-94-015-8070-0_11  0.452
1988 Wheeler ME, Luscinskas FW, Bevilacqua MP, Gimbrone MA. Cultured human endothelial cells stimulated with cytokines or endotoxin produce an inhibitor of leukocyte adhesion. The Journal of Clinical Investigation. 82: 1211-8. PMID 3049673 DOI: 10.1172/Jci113718  0.441
1988 Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, Gimbrone MA. Identification of an inducible endothelial-leukocyte adhesion molecule. Proceedings of the National Academy of Sciences of the United States of America. 84: 9238-42. PMID 2827173 DOI: 10.1073/Pnas.84.24.9238  0.457
1987 Muller WA, Gimbrone MA. Plasmalemmal proteins of cultured vascular endothelial cells exhibit apical-basal polarity: analysis by surface-selective iodination. The Journal of Cell Biology. 103: 2389-402. PMID 3782302 DOI: 10.1083/Jcb.103.6.2389  0.401
1987 Bevilacqua MP, Gimbrone MA. Inducible Endothelial Functions in Inflammation and Coagulation Seminars in Thrombosis and Hemostasis. 13: 425-433. PMID 3122325 DOI: 10.1055/S-2007-1003519  0.487
1987 Takayama H, Gimbrone MA, Schafer AI. Vascular lipoxygenase activity: synthesis of 15-hydroxyeicosatetraenoic acid from arachidonic acid by blood vessels and cultured vascular endothelial cells. Thrombosis Research. 45: 803-816. PMID 3109068 DOI: 10.1016/0049-3848(87)90090-9  0.424
1987 Griendling KK, Berk BC, Ganz P, Gimbrone MA, Alexander RW. Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture. Hypertension (Dallas, Tex. : 1979). 9: III181-5. PMID 3036701 DOI: 10.1161/01.Hyp.9.6_Pt_2.Iii181  0.339
1986 Cotran RS, Gimbrone MA, Bevilacqua MP, Mendrick DL, Pober JS. Induction and detection of a human endothelial activation antigen in vivo. The Journal of Experimental Medicine. 164: 661-6. PMID 3723080 DOI: 10.1084/Jem.164.2.661  0.367
1986 Brock TA, Gimbrone MA. Platelet activating factors alters calcium homeostasis in cultured vascular endothelial cells. The American Journal of Physiology. 250: H1086-92. PMID 3717361 DOI: 10.1152/Ajpheart.1986.250.6.H1086  0.385
1986 Bevilacqua MP, Pober JS, Majeau GR, Fiers W, Cotran RS, Gimbrone MA. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proceedings of the National Academy of Sciences of the United States of America. 83: 4533-7. PMID 3487091 DOI: 10.1073/Pnas.83.12.4533  0.435
1986 Berk BC, Alexander RW, Brock TA, Gimbrone MA, Webb RC. Vasoconstriction: a new activity for platelet-derived growth factor. Science (New York, N.Y.). 232: 87-90. PMID 3485309 DOI: 10.1126/Science.3485309  0.38
1986 Davies PF, Remuzzi A, Gordon EJ, Dewey CF, Gimbrone MA. Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro Proceedings of the National Academy of Sciences of the United States of America. 83: 2114-2117. PMID 3457378 DOI: 10.1073/Pnas.83.7.2114  0.765
1986 Bevilacqua MP, Schleef RR, Gimbrone MA, Loskutoff DJ. Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1. Journal of Clinical Investigation. 78: 587-591. PMID 3090105 DOI: 10.1172/Jci112613  0.313
1986 Colucci WS, Gimbrone MA, Alexander RW. Phorbol diester modulates alpha-adrenergic receptor-coupled calcium efflux and alpha-adrenergic receptor number in cultured vascular smooth muscle cells. Circulation Research. 58: 393-8. PMID 3013460 DOI: 10.1161/01.Res.58.3.393  0.312
1986 Ganz P, Sandrock AW, Landis SC, Leopold J, Gimbrone MA, Alexander RW. Vasoactive intestinal peptide: vasodilatation and cyclic AMP generation. The American Journal of Physiology. 250: H755-60. PMID 3010741 DOI: 10.1152/Ajpheart.1986.250.5.H755  0.355
1986 Ganz P, Davies PF, Leopold JA, Gimbrone MA, Alexander RW. Short- and long-term interactions of endothelium and vascular smooth muscle in coculture: Effects on cyclic GMP production Proceedings of the National Academy of Sciences of the United States of America. 83: 3552-3556. PMID 3010304 DOI: 10.1073/Pnas.83.10.3552  0.403
1986 Pober JS, Collins T, Gimbrone MA, Libby P, Reiss CS. Inducible expression of class II major histocompatibility complex antigens and the immunogenicity of vascular endothelium. Transplantation. 41: 141-6. PMID 2935977 DOI: 10.1097/00007890-198602000-00001  0.329
1986 Einav S, Dewey C, Davies P, Gimbrone M. Time varying turbulent fluid characteristics and vascular endothelium Thrombosis Research. 41: 132. DOI: 10.1016/0049-3848(86)91609-9  0.423
1985 Pober JS, Gimbrone MA, Collins T, Cotran RS, Ault KA, Fiers W, Krensky AM, Clayberger C, Reiss CS, Burakoff SJ. Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens. Immunobiology. 168: 483-94. PMID 6397428 DOI: 10.1016/S0171-2985(84)80132-1  0.396
1985 Brock TA, Alexander RW, Ekstein LS, Atkinson WJ, Gimbrone MA. Angiotensin increases cytosolic free calcium in cultured vascular smooth muscle cells. Hypertension. 7: I105-9. PMID 3922884 DOI: 10.1161/01.Hyp.7.3_Pt_2.I105  0.331
1985 Lilly LS, Pratt RE, Alexander RW, Larson DM, Ellison KE, Gimbrone MA, Dzau VJ. Renin expression by vascular endothelial cells in culture Circulation Research. 57: 312-318. PMID 3893789 DOI: 10.1161/01.Res.57.2.312  0.469
1985 Bevilacqua MP, Pober JS, Wheeler ME, Cotran RS, Gimbrone MA. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. The Journal of Clinical Investigation. 76: 2003-11. PMID 3877078 DOI: 10.1172/Jci112200  0.438
1985 Berk BC, Brock TA, Webb RC, Taubman MB, Atkinson WJ, Gimbrone MA, Alexander RW. Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction. The Journal of Clinical Investigation. 75: 1083-6. PMID 3872314 DOI: 10.1172/Jci111772  0.354
1985 Alexander RW, Brock TA, Gimbrone MA, Rittenhouse SE. Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle. Hypertension. 7: 447-451. DOI: 10.1161/01.Hyp.7.3.447  0.304
1984 Davies PF, Dewey CF, Bussolari SR, Gordon EJ, Gimbrone MA. Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells Journal of Clinical Investigation. 73: 1121-1129. PMID 6707208 DOI: 10.1172/Jci111298  0.751
1984 Schafer AI, Crawford DD, Gimbrone MA. Unidirectional transfer of prostaglandin endoperoxides between platelets and endothelial cells. Journal of Clinical Investigation. 73: 1105-1112. PMID 6423665 DOI: 10.1172/Jci111296  0.409
1984 Bevilacqua MP, Pober JS, Majeau GR, Cotran RS, Gimbrone MA. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. The Journal of Experimental Medicine. 160: 618-23. PMID 6332168 DOI: 10.1084/Jem.160.2.618  0.405
1984 Colucci WS, Brock TA, Gimbrone MA, Alexander RW. Regulation of alpha 1-adrenergic receptor-coupled calcium flux in cultured vascular smooth muscle cells. Hypertension. 6: I19-24. PMID 6327521 DOI: 10.1161/01.Hyp.6.2_Pt_2.I19  0.336
1984 Larson DM, Fujiwara K, Alexander RW, Gimbrone MA. Myosin in cultured vascular smooth muscle cells: Immunofluorescence and immunochemical studies of alterations in antigenic expression Journal of Cell Biology. 99: 1582-1589. PMID 6208199 DOI: 10.1083/Jcb.99.5.1582  0.374
1984 Gimbrone MA, Brock AF, Schafer AI. Leukotriene B4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells. Journal of Clinical Investigation. 74: 1552-1555. PMID 6090507 DOI: 10.1172/Jci111570  0.493
1984 Colucci WS, Gimbrone MA, Alexander RW. Regulation of myocardial and vascular alpha-adrenergic receptor affinity. Effects of guanine nucleotides, cations, estrogen, and catecholamine depletion. Circulation Research. 55: 78-88. PMID 6086174 DOI: 10.1161/01.Res.55.1.78  0.309
1983 White GE, Gimbrone MA, Fujiwara K. Factors influencing the expression of stress fibers in vascular endothelial cells in situ Journal of Cell Biology. 97: 416-424. PMID 6684121 DOI: 10.1083/Jcb.97.2.416  0.452
1983 Pober JS, Collins T, Gimbrone MA, Cotran RS, Gitlin JD, Fiers W, Clayberger C, Krensky AM, Burakoff SJ, Reiss CS. Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon Nature. 305: 726-729. PMID 6415484 DOI: 10.1038/305726A0  0.369
1983 Pober JS, Gimbrone MA, Cotran RS, Reiss CS, Burakoff SJ, Fiers W, Ault KA. Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon. The Journal of Experimental Medicine. 157: 1339-53. PMID 6403654 DOI: 10.1084/Jem.157.4.1339  0.449
1982 Bussolari SR, Dewey CF, Gimbrone MA. Apparatus for subjecting living cells to fluid shear stress. The Review of Scientific Instruments. 53: 1851-4. PMID 7156852 DOI: 10.1063/1.1136909  0.699
1982 Gimbrone MA, Buchanan MR. INTERACTIONS OF PLATELETS AND LEUKOCYTES WITH VASCULAR ENDOTHELIUM: In Vitro STUDIES* Annals of the New York Academy of Sciences. 401: 171-182. PMID 6820246 DOI: 10.1111/J.1749-6632.1982.Tb25716.X  0.472
1982 Pober JS, Gimbrone MA. Expression of Ia-like antigens by human vascular endothelial cells is inducible in vitro: Demonstration by monoclonal antibody binding and immunoprecipitation Proceedings of the National Academy of Sciences of the United States of America. 79: 6641-6645. PMID 6815654 DOI: 10.1073/Pnas.79.21.6641  0.424
1982 Gunther S, Alexander RW, Atkinson WJ, Gimbrone MA. Functional angiotensin II receptors in cultured vascular smooth muscle cells. Journal of Cell Biology. 92: 289-298. PMID 6277961 DOI: 10.1083/Jcb.92.2.289  0.388
1981 Dewey CF, Bussolari SR, Gimbrone MA, Davies PF. The dynamic response of vascular endothelial cells to fluid shear stress Journal of Biomechanical Engineering. 103: 177-185. PMID 7278196 DOI: 10.1115/1.3138276  0.766
1980 Schafer AI, Gimbrone MA, Handin RI. Endothelial cell adenylate cyclase: activation by catecholamines and prostaglandin I2+. Biochemical and Biophysical Research Communications. 96: 1640-1647. PMID 6255950 DOI: 10.1016/0006-291X(80)91362-5  0.418
1980 Gunther S, Gimbrone MA, Alexander RW. Regulation by angiotensin II of its receptors in resistance blood vessels Nature. 287: 230-232. PMID 6253796 DOI: 10.1038/287230A0  0.305
1980 Gunther S, Gimbrone MA, Alexander RW. Identification and characterization of the high affinity vascular angiotensin II receptor in rat mesenteric artery. Circulation Research. 47: 278-286. PMID 6156775 DOI: 10.1161/01.Res.47.2.278  0.317
1979 Pelikan P, Gimbrone MA, Cotran RS. Distribution and movement of anionic cell surface sites in cultured human vascular endothelial cells Atherosclerosis. 32: 69-80. PMID 465114 DOI: 10.1016/0021-9150(79)90148-5  0.383
1979 Hial V, Gimbrone MA, Peyton MP, Wilcox GM, Pisano JJ. Angiotensin metabolism by cultured human vascular endothelial and smooth muscle cells. Microvascular Research. 17: 314-29. PMID 223017 DOI: 10.1016/S0026-2862(79)80007-2  0.419
1977 Polverini PJ, Cotran RS, Gimbrone MA, Unanue ER. Activated macrophages induce vascular proliferation Nature. 269: 804-806. PMID 927505 DOI: 10.1038/269804A0  0.408
1976 Alexander RW, Gimbrone MA. Stimulation of prostaglandin E synthesis in cultured human umbilical vein smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 73: 1617-1620. PMID 1064032 DOI: 10.1073/Pnas.73.5.1617  0.333
1976 Gimbrone MA, Fareed GC. Transformation of cultured human vascular endothelium by SV40 DNA. Cell. 9: 685-693. PMID 189941 DOI: 10.1016/0092-8674(76)90132-X  0.353
1975 Gimbrone M, Alexander R. Angiotensin II stimulation of prostaglandin production in cultured human vascular endothelium Science. 189: 219-220. PMID 1138377 DOI: 10.1126/Science.1138377  0.43
1975 Haudenschild CC, Cotran RS, Gimbrone MA, Folkman J. Fine structure of vascular endothelium in culture. Journal of Ultrastructure Research. 50: 22-32. PMID 1089799 DOI: 10.1016/S0022-5320(75)90004-0  0.414
1974 Gimbrone MA, Cotran RS, Folkman J. HUMAN VASCULAR ENDOTHELIAL CELLS IN CULTURE Growth and DNA Synthesis Journal of Cell Biology. 60: 673-684. PMID 4363161 DOI: 10.1083/Jcb.60.3.673  0.437
1972 Gimbrone MA, Leapman SB, Cotran RS, Folkman J. Tumor dormancy in vivo by prevention of neovascularization. Journal of Experimental Medicine. 136: 261-276. PMID 5043412 DOI: 10.1084/Jem.136.2.261  0.32
1969 Gimbrone MA, Aster RH, Cotran RS, Corkery J, Jandl JH, Folkman J. Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature. 222: 33-36. PMID 5775827 DOI: 10.1038/222033A0  0.307
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