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Ying-Ying Wang, Ph.D. - Publications

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Pharmacology, Nanotechnology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jensen MA, Wang YY, Lai SK, Forest MG, McKinley SA. Antibody-Mediated Immobilization of Virions in Mucus. Bulletin of Mathematical Biology. PMID 31468263 DOI: 10.1007/S11538-019-00653-6  0.527
2018 Ayehunie S, Wang YY, Landry T, Bogojevic S, Cone RA. Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model. Toxicology Reports. 5: 134-140. PMID 29854584 DOI: 10.1016/J.Toxrep.2017.12.011  0.318
2018 Yang B, Schaefer A, Wang YY, McCallen J, Lee P, Newby JM, Arora H, Kumar PA, Zeitlin L, Whaley KJ, McKinley SA, Fischer WA, Harit D, Lai SK. ZMappTM Reinforces the Airway Mucosal Barrier Against Ebola Virus. The Journal of Infectious Diseases. PMID 29688496 DOI: 10.1093/Infdis/Jiy230  0.579
2017 Wang YY, Harit D, Subramani DB, Arora H, Kumar PA, Lai SK. Influenza-binding antibodies immobilise influenza viruses in fresh human airway mucus. The European Respiratory Journal. 49. PMID 28122865 DOI: 10.1183/13993003.01709-2016  0.471
2016 Henry CE, Wang YY, Yang Q, Hoang T, Chattopadhyay S, Hoen T, Ensign LM, Nunn KL, Schroeder H, McCallen J, Moench T, Cone R, Roffler SR, Lai SK. Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus. Acta Biomaterialia. PMID 27424083 DOI: 10.1016/J.Actbio.2016.07.019  0.606
2016 Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA. Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus. Plos One. 11: e0158338. PMID 27362256 DOI: 10.1371/Journal.Pone.0158338  0.469
2016 Wang YY, Zhang DD, Kong YY, Shao LL, Zhang FY, Gao Y, Mu X, Wang J, Li HF, Yu SQ, Xu Q. CS/PAA@TPGS/PLGA nanoparticles with intracellular pH-sensitive sequential release for delivering drug to the nucleus of MDR cells. Colloids and Surfaces. B, Biointerfaces. 145: 716-727. PMID 27289313 DOI: 10.1016/j.colsurfb.2016.05.088  0.34
2015 Wang YY, Nunn KL, Harit D, McKinley SA, Lai SK. Minimizing biases associated with tracking analysis of submicron particles in heterogeneous biological fluids. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26478013 DOI: 10.1016/J.Jconrel.2015.10.021  0.597
2015 Nunn KL, Wang YY, Harit D, Humphrys MS, Ma B, Cone R, Ravel J, Lai SK. Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota. Mbio. 6. PMID 26443453 DOI: 10.1128/Mbio.01084-15  0.518
2014 Ensign LM, Lai SK, Wang YY, Yang M, Mert O, Hanes J, Cone R. Pretreatment of human cervicovaginal mucus with pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virus. Biomacromolecules. 15: 4403-9. PMID 25347518 DOI: 10.1021/Bm501419Z  0.672
2014 Yang M, Lai SK, Yu T, Wang YY, Happe C, Zhong W, Zhang M, Anonuevo A, Fridley C, Hung A, Fu J, Hanes J. Nanoparticle penetration of human cervicovaginal mucus: the effect of polyvinyl alcohol. Journal of Controlled Release : Official Journal of the Controlled Release Society. 192: 202-8. PMID 25090196 DOI: 10.1016/J.Jconrel.2014.07.045  0.735
2014 Yang M, Yu T, Wood J, Wang YY, Tang BC, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Delivery and Translational Research. 4: 203-9. PMID 24816829 DOI: 10.1007/S13346-013-0190-7  0.729
2014 Wang YY, Kannan A, Nunn KL, Murphy MA, Subramani DB, Moench T, Cone R, Lai SK. IgG in cervicovaginal mucus traps HSV and prevents vaginal herpes infections. Mucosal Immunology. 7: 1036-44. PMID 24496316 DOI: 10.1038/Mi.2013.120  0.529
2014 Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, et al. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Advanced Healthcare Materials. 3: 1044-52. PMID 24339398 DOI: 10.1002/Adhm.201300519  0.787
2014 Yang M, Yu T, Wang Y, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang C, Mert O, Wood J, Fu J, et al. Cancer Therapy: Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth (Adv. Healthcare Mater. 7/2014) Advanced Healthcare Materials. 3: 1120-1120. DOI: 10.1002/Adhm.201470037  0.75
2013 Wang YY, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J. The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. Biomacromolecules. 14: 4429-35. PMID 24266646 DOI: 10.1021/Bm401356Q  0.613
2013 Ensign LM, Henning A, Schneider CS, Maisel K, Wang YY, Porosoff MD, Cone R, Hanes J. Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues. Molecular Pharmaceutics. 10: 2176-82. PMID 23617606 DOI: 10.1021/Mp400087Y  0.612
2013 Xu Q, Boylan NJ, Suk JS, Wang YY, Nance EA, Yang JC, McDonnell PJ, Cone RA, Duh EJ, Hanes J. Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 167: 76-84. PMID 23369761 DOI: 10.1016/J.Jconrel.2013.01.018  0.779
2012 Yu T, Wang YY, Yang M, Schneider C, Zhong W, Pulicare S, Choi WJ, Mert O, Fu J, Lai SK, Hanes J. Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid). Drug Delivery and Translational Research. 2. PMID 24205449 DOI: 10.1007/S13346-011-0048-9  0.741
2012 Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Science Translational Medicine. 4: 138ra79. PMID 22700955 DOI: 10.1126/Scitranslmed.3003453  0.735
2012 Mert O, Lai SK, Ensign L, Yang M, Wang YY, Wood J, Hanes J. A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 455-60. PMID 21911015 DOI: 10.1016/J.Jconrel.2011.08.032  0.714
2011 Wang YY, Lai SK, So C, Schneider C, Cone R, Hanes J. Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure. Plos One. 6: e21547. PMID 21738703 DOI: 10.1371/Journal.Pone.0021547  0.694
2011 Lai SK, Suk JS, Pace A, Wang YY, Yang M, Mert O, Chen J, Kim J, Hanes J. Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus. Biomaterials. 32: 6285-90. PMID 21665271 DOI: 10.1016/J.Biomaterials.2011.05.008  0.787
2011 Yang M, Lai SK, Wang YY, Zhong W, Happe C, Zhang M, Fu J, Hanes J. Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus. Angewandte Chemie (International Ed. in English). 50: 2597-600. PMID 21370345 DOI: 10.1002/Anie.201006849  0.725
2010 Lai SK, Wang YY, Hida K, Cone R, Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 598-603. PMID 20018745 DOI: 10.1073/Pnas.0911748107  0.725
2009 Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proceedings of the National Academy of Sciences of the United States of America. 106: 19268-73. PMID 19901335 DOI: 10.1073/Pnas.0905998106  0.805
2009 Lai SK, Hida K, Shukair S, Wang YY, Figueiredo A, Cone R, Hope TJ, Hanes J. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. Journal of Virology. 83: 11196-200. PMID 19692470 DOI: 10.1128/Jvi.01899-08  0.677
2009 Suk JS, Lai SK, Wang YY, Ensign LM, Zeitlin PL, Boyle MP, Hanes J. The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles. Biomaterials. 30: 2591-7. PMID 19176245 DOI: 10.1016/J.Biomaterials.2008.12.076  0.787
2009 Lai SK, Wang YY, Cone R, Wirtz D, Hanes J. Altering mucus rheology to "solidify" human mucus at the nanoscale. Plos One. 4: e4294. PMID 19173002 DOI: 10.1371/Journal.Pone.0004294  0.667
2009 Lai SK, Wang YY, Wirtz D, Hanes J. Micro- and macrorheology of mucus. Advanced Drug Delivery Reviews. 61: 86-100. PMID 19166889 DOI: 10.1016/J.Addr.2008.09.012  0.664
2009 Lai SK, Wang YY, Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Advanced Drug Delivery Reviews. 61: 158-71. PMID 19133304 DOI: 10.1016/J.Addr.2008.11.002  0.699
2008 Wang YY, Lai SK, Suk JS, Pace A, Cone R, Hanes J. Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier. Angewandte Chemie (International Ed. in English). 47: 9726-9. PMID 18979480 DOI: 10.1002/Anie.200803526  0.783
2007 Lai SK, O'Hanlon DE, Harrold S, Man ST, Wang YY, Cone R, Hanes J. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus. Proceedings of the National Academy of Sciences of the United States of America. 104: 1482-7. PMID 17244708 DOI: 10.1073/Pnas.0608611104  0.742
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