Denis Wirtz - Publications

Chemical and Biomolecular Engineering Johns Hopkins University, Baltimore, MD 
Cell Biology, Physiology Biology, General Biophysics

229 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Phillip JM, Zamponi N, Phillip MP, Daya J, McGovern S, Williams W, Tschudi K, Jayatilaka H, Wu PH, Walston J, Wirtz D. Fractional re-distribution among cell motility states during ageing. Communications Biology. 4: 81. PMID 33469145 DOI: 10.1038/s42003-020-01605-w  0.4
2021 Phillip JM, Han KS, Chen WC, Wirtz D, Wu PH. A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei. Nature Protocols. PMID 33424024 DOI: 10.1038/s41596-020-00432-x  0.48
2020 Rochman ND, Yao K, Gonzalez NPA, Wirtz D, Sun SX. Single Cell Volume Measurement Utilizing the Fluorescence Exclusion Method (FXm). Bio-Protocol. 10: e3652. PMID 33659322 DOI: 10.21769/BioProtoc.3652  0.52
2020 Yoshizawa T, Hong SM, Jung D, Noë M, Keimen A, Wu PH, Wirtz D, Hruban RH, Wood LD, Oshima K. Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding. The Journal of Pathology. PMID 32476131 DOI: 10.1002/Path.5474  0.32
2020 Wu PH, Gilkes DM, Phillip JM, Narkar A, Cheng TW, Marchand J, Lee MH, Li R, Wirtz D. Single-cell morphology encodes metastatic potential. Science Advances. 6: eaaw6938. PMID 32010778 DOI: 10.1126/Sciadv.Aaw6938  0.4
2020 Chakroun RW, Sneider A, Anderson CF, Wang F, Wu PH, Wirtz D, Cui H. Supramolecular Design of Unsymmetric Reverse Bolaamphiphiles for Cell-Sensitive Hydrogel Degradation and Drug Release. Angewandte Chemie (International Ed. in English). PMID 31943628 DOI: 10.1002/Anie.201913087  0.52
2020 Duan X, Li Y, Yi K, Guo F, Wang H, Wu PH, Yang J, Mair DB, Morales EA, Kalab P, Wirtz D, Sun SX, Li R. Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes. Nature Communications. 11: 277. PMID 31937754 DOI: 10.1038/S41467-019-14068-3  0.52
2020 Wu PH, Gambhir SS, Hale CM, Chen WC, Wirtz D, Smith BR. Particle tracking microrheology of cancer cells in living subjects Materials Today. DOI: 10.1016/J.Mattod.2020.03.021  0.6
2019 Hong SM, Jung D, Kiemen A, Gaida MM, Yoshizawa T, Braxton AM, Noë M, Lionheart G, Oshima K, Thompson ED, Burkhart R, Wu PH, Wirtz D, Hruban RH, Wood LD. Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31700162 DOI: 10.1038/S41379-019-0409-3  0.32
2019 Perez-Gonzalez NA, Rochman ND, Yao K, Tao J, Le MT, Flanary S, Sablich L, Toler B, Crentsil E, Takaesu F, Lambrus B, Huang J, Fu V, Chengappa P, Jones TM, ... ... Wirtz D, et al. YAP and TAZ regulate cell volume. The Journal of Cell Biology. PMID 31481532 DOI: 10.1083/Jcb.201902067  0.52
2018 Kim DH, Hah J, Wirtz D. Mechanics of the Cell Nucleus. Advances in Experimental Medicine and Biology. 1092: 41-55. PMID 30368747 DOI: 10.1007/978-3-319-95294-9_3  0.96
2018 Harris MJ, Wirtz D, Wu PH. Dissecting cellular mechanics: Implications for aging, cancer, and immunity. Seminars in Cell & Developmental Biology. PMID 30359779 DOI: 10.1016/J.Semcdb.2018.10.008  0.32
2018 Sneider A, Hah J, Wirtz D, Kim DH. Recapitulation of molecular regulators of nuclear motion during cell migration. Cell Adhesion & Migration. 1-13. PMID 30261154 DOI: 10.1080/19336918.2018.1506654  0.96
2018 Jayatilaka H, Umanzor FG, Shah V, Meirson T, Russo G, Starich B, Tyle P, Lee JSH, Khatau S, Gil-Henn H, Wirtz D. Tumor cell density regulates matrix metalloproteinases for enhanced migration. Oncotarget. 9: 32556-32569. PMID 30220965 DOI: 10.18632/Oncotarget.25863  0.64
2018 Gonzalez NP, Tao J, Rochman ND, Vig D, Wirtz D, Sun SX. Cell Tension and Mechanical Regulation of Cell Volume. Molecular Biology of the Cell. mbcE18040213. PMID 30113884 DOI: 10.1091/Mbc.E18-04-0213  0.52
2018 Wu PH, Aroush DR, Asnacios A, Chen WC, Dokukin ME, Doss BL, Durand-Smet P, Ekpenyong A, Guck J, Guz NV, Janmey PA, Lee JSH, Moore NM, Ott A, Poh YC, ... ... Wirtz D, et al. A comparison of methods to assess cell mechanical properties. Nature Methods. PMID 29915189 DOI: 10.1038/S41592-018-0015-1  0.64
2018 Parekh A, Das S, Parida S, Das CK, Dutta D, Mallick SK, Wu PH, Kumar BNP, Bharti R, Dey G, Banerjee K, Rajput S, Bharadwaj D, Pal I, Dey KK, ... ... Wirtz D, et al. Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo. Oncogene. PMID 29743594 DOI: 10.1038/S41388-018-0272-6  0.32
2018 Noë M, Rezaee N, Asrani K, Skaro M, Groot VP, Wu PH, Olson MT, Hong SM, Kim SJ, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wirtz D, et al. Immunolabeling of Cleared Human Pancreata Provides Insights into Three-dimensional Pancreatic Anatomy and Pathology. The American Journal of Pathology. PMID 29684363 DOI: 10.1016/J.Ajpath.2018.04.002  0.32
2018 Yu Y, Suryo Rahmanto Y, Lee MH, Wu PH, Phillip JM, Huang CH, Vitolo MI, Gaillard S, Martin SS, Wirtz D, Shih IM, Wang TL. Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. Oncogene. PMID 29643476 DOI: 10.1038/S41388-018-0241-0  0.4
2018 Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH. Author Correction: Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology. Nature Communications. 9: 1115. PMID 29535303 DOI: 10.1038/S41467-018-03450-2  0.96
2018 He L, Tao J, Maity D, Si F, Wu Y, Wu T, Prasath V, Wirtz D, Sun SX. Role of membrane-tension gated Ca flux in cell mechanosensation. Journal of Cell Science. PMID 29361533 DOI: 10.1242/Jcs.208470  0.52
2017 Phillip JM, Wu PH, Gilkes DM, Williams W, McGovern S, Daya J, Chen J, Aifuwa I, Lee JSH, Fan R, Walston J, Wirtz D. Biophysical and biomolecular determination of cellular age in humans. Nature Biomedical Engineering. 1. PMID 31372309 DOI: 10.1038/S41551-017-0093  0.64
2017 He L, Sneider A, Chen W, Karl M, Prasath V, Wu PH, Mattson G, Wirtz D. Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy. Journal of Visualized Experiments : Jove. PMID 29286363 DOI: 10.3791/56364  0.52
2017 Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH. Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology. Nature Communications. 8: 2123. PMID 29242553 DOI: 10.1038/S41467-017-02217-5  0.96
2017 Lin YA, Kang M, Chen WC, Ou YC, Cheetham AG, Wu PH, Wirtz D, Loverde SM, Cui H. Isomeric control of the mechanical properties of supramolecular filament hydrogels. Biomaterials Science. 6: 216-224. PMID 29214247 DOI: 10.1039/C7Bm00722A  0.48
2017 Li Y, He L, Gonzalez NAP, Graham J, Wolgemuth C, Wirtz D, Sun SX. Going with the Flow: Water Flux and Cell Shape during Cytokinesis. Biophysical Journal. 113: 2487-2495. PMID 29212002 DOI: 10.1016/J.Bpj.2017.09.026  0.52
2017 Jayatilaka H, Giri A, Karl M, Aifuwa I, Trenton NJ, Phillip JM, Khatau S, Wirtz D. EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29097501 DOI: 10.1096/Fj.201700444Rr  0.4
2017 Stroka KM, Wong BS, Shriver M, Phillip JM, Wirtz D, Kontrogianni-Konstantopoulos A, Konstantopoulos K. Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness. Oncotarget. 8: 54004-54020. PMID 28903319 DOI: 10.18632/Oncotarget.10997  0.48
2017 Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D. Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration. Nature Communications. 8: 15584. PMID 28548090 DOI: 10.1038/Ncomms15584  0.64
2017 Wang Y, Gong J, Wirtz D, Schafer BW. Affine and non-affine deformations quantified in cytoskeletal networks through three-dimensional form-finding model. Journal of the Mechanical Behavior of Biomedical Materials. 72: 52-65. PMID 28448922 DOI: 10.1016/J.Jmbbm.2017.04.015  0.6
2017 Ju JA, Godet I, Ye IC, Byun J, Jayatilaka H, Lee SJ, Xiang L, Samanta D, Lee MH, Wu PH, Wirtz D, Semenza GL, Gilkes DM. Hypoxia Selectively Enhances Integrin Receptor Expression to Promote Metastasis. Molecular Cancer Research : McR. PMID 28213554 DOI: 10.1158/1541-7786.Mcr-16-0338  0.32
2017 Agarwal A, Wu PH, Hughes EG, Fukaya M, Tischfield MA, Langseth AJ, Wirtz D, Bergles DE. Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes. Neuron. PMID 28132831 DOI: 10.1016/J.Neuron.2016.12.034  0.32
2016 Stroka KM, Wong BS, Shriver M, Phillip JM, Wirtz D, Kontrogianni-Konstantopoulos A, Konstantopoulos K. Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness. Oncotarget. PMID 27494856 DOI: 10.18632/oncotarget.10997  0.48
2016 Paul CD, Hung WC, Wirtz D, Konstantopoulos K. Engineered Models of Confined Cell Migration. Annual Review of Biomedical Engineering. 18: 159-180. PMID 27420571 DOI: 10.1146/Annurev-Bioeng-071114-040654  1
2016 Hung WC, Yang JR, Yankaskas CL, Wong BS, Wu PH, Pardo-Pastor C, Serra SA, Chiang MJ, Gu Z, Wirtz D, Valverde MA, Yang JT, Zhang J, Konstantopoulos K. Confinement-Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways. Cell Reports. PMID 27160899 DOI: 10.1016/J.Celrep.2016.04.035  0.48
2016 Shah MY, Martinez-Garcia E, Phillip JM, Chambliss AB, Popovic R, Ezponda T, Small EC, Will C, Phillip MP, Neri P, Bahlis NJ, Wirtz D, Licht JD. MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents. Oncogene. PMID 27109101 DOI: 10.1038/Onc.2016.116  0.4
2016 Hecht VC, Sullivan LB, Kimmerling RJ, Kim DH, Hosios AM, Stockslager MA, Stevens MM, Kang JH, Wirtz D, Vander Heiden MG, Manalis SR. Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes. The Journal of Cell Biology. 212: 439-47. PMID 26880201 DOI: 10.1083/Jcb.201506118  0.96
2016 Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL. Differential vesicular sorting of AMPA and GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 26839408 DOI: 10.1073/Pnas.1525726113  0.32
2016 Sarnecki JS, Burns KH, Wood LD, Waters KM, Hruban RH, Wirtz D, Wu PH. A robust nonlinear tissue-component discrimination method for computational pathology. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26779829 DOI: 10.1038/Labinvest.2015.162  1
2016 Kim DH, Li B, Si F, Phillip JM, Wirtz D, Sun SX. Volume regulation and shape bifurcation in the cell nucleus. Journal of Cell Science. 129: 457. PMID 26773007 DOI: 10.1242/Jcs.185173  1
2015 Wu PH, Phillip JM, Khatau SB, Chen WC, Stirman J, Rosseel S, Tschudi K, Van Patten J, Wong M, Gupta S, Baras AS, Leek JT, Maitra A, Wirtz D. Evolution of cellular morpho-phenotypes in cancer metastasis. Scientific Reports. 5: 18437. PMID 26675084 DOI: 10.1038/Srep18437  1
2015 Phillip JM, Aifuwa I, Walston J, Wirtz D. The Mechanobiology of Aging. Annual Review of Biomedical Engineering. 17: 113-41. PMID 26643020 DOI: 10.1146/Annurev-Bioeng-071114-040829  1
2015 Jimenez Valencia AM, Wu PH, Yogurtcu ON, Rao P, DiGiacomo J, Godet I, He L, Lee MH, Gilkes D, Sun SX, Wirtz D. Collective cancer cell invasion induced by coordinated contractile stresses. Oncotarget. PMID 26528856 DOI: 10.18632/Oncotarget.5874  1
2015 He L, Chen W, Wu PH, Jimenez A, Wong BS, San A, Konstantopoulos K, Wirtz D. Local 3D matrix confinement determines division axis through cell shape. Oncotarget. PMID 26515603 DOI: 10.18632/Oncotarget.5848  1
2015 Aifuwa I, Giri A, Longe N, Lee SH, An SS, Wirtz D. Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility. Oncotarget. 6: 30516-31. PMID 26483365 DOI: 10.18632/Oncotarget.5854  1
2015 Fraley SI, Wu PH, He L, Feng Y, Krisnamurthy R, Longmore GD, Wirtz D. Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions. Scientific Reports. 5: 14580. PMID 26423227 DOI: 10.1038/Srep14580  1
2015 Lee MH, Wu PH, Gilkes D, Aifuwa I, Wirtz D. Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions. Oncotarget. PMID 26334095 DOI: 10.18632/Oncotarget.4728  1
2015 Shea DJ, Wirtz D, Stebe KJ, Konstantopoulos K. Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow. Oncotarget. 6: 24842-55. PMID 26329844 DOI: 10.18632/Oncotarget.4704  1
2015 Kim DH, Li B, Si F, Philips J, Wirtz D, Sun SX. Volume regulation and shape bifurcation in the cell nucleus. Journal of Cell Science. PMID 26243474 DOI: 10.1242/Jcs.166330  1
2015 Palmieri B, Bresler Y, Wirtz D, Grant M. Multiple scale model for cell migration in monolayers: Elastic mismatch between cells enhances motility. Scientific Reports. 5: 11745. PMID 26134134 DOI: 10.1038/Srep11745  1
2015 Yu Y, Gaillard S, Phillip JM, Huang TC, Pinto SM, Tessarollo NG, Zhang Z, Pandey A, Wirtz D, Ayhan A, Davidson B, Wang TL, Shih IeM. Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules. Cancer Cell. 28: 82-96. PMID 26096845 DOI: 10.1016/J.Ccell.2015.05.009  1
2015 Wu PH, Giri A, Wirtz D. Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model. Nature Protocols. 10: 517-27. PMID 25719270 DOI: 10.1038/Nprot.2015.030  1
2015 Yoon AR, Stasinopoulos I, Kim JH, Yong HM, Kilic O, Wirtz D, Bhujwalla ZM, An SS. COX-2 dependent regulation of mechanotransduction in human breast cancer cells. Cancer Biology & Therapy. 16: 430-7. PMID 25701047 DOI: 10.1080/15384047.2014.1003004  1
2015 Kim DH, Wirtz D. Cytoskeletal tension induces the polarized architecture of the nucleus. Biomaterials. 48: 161-72. PMID 25701041 DOI: 10.1016/J.Biomaterials.2015.01.023  1
2014 He L, Wirtz D. Switching from protease-independent to protease-dependent cancer cell invasion. Biophysical Journal. 107: 2484-5. PMID 25468324 DOI: 10.1016/J.Bpj.2014.10.047  1
2014 Gilkes DM, Semenza GL, Wirtz D. Hypoxia and the extracellular matrix: drivers of tumour metastasis. Nature Reviews. Cancer. 14: 430-9. PMID 24827502 DOI: 10.1038/Nrc3726  1
2014 Stroka KM, Jiang H, Chen SH, Tong Z, Wirtz D, Sun SX, Konstantopoulos K. Water permeation drives tumor cell migration in confined microenvironments. Cell. 157: 611-23. PMID 24726433 DOI: 10.1016/J.Cell.2014.02.052  1
2014 Castillo M, Ebensperger R, Wirtz D, Walczak M, Hurtado DE, Celedon A. Local mechanical response of cells to the controlled rotation of magnetic nanorods. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 102: 1779-85. PMID 24700696 DOI: 10.1002/Jbm.B.33167  1
2014 Kim DH, Cho S, Wirtz D. Tight coupling between nucleus and cell migration through the perinuclear actin cap. Journal of Cell Science. 127: 2528-41. PMID 24639463 DOI: 10.1016/J.Bpj.2013.11.316  1
2014 Wu PH, Giri A, Sun SX, Wirtz D. Three-dimensional cell migration does not follow a random walk. Proceedings of the National Academy of Sciences of the United States of America. 111: 3949-54. PMID 24594603 DOI: 10.1073/Pnas.1318967111  1
2014 Razafsky D, Wirtz D, Hodzic D. Nuclear envelope in nuclear positioning and cell migration. Advances in Experimental Medicine and Biology. 773: 471-90. PMID 24563361 DOI: 10.1007/978-1-4899-8032-8_21  1
2014 Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E384-93. PMID 24324133 DOI: 10.1073/Pnas.1321510111  1
2014 Aw Yong KM, Zeng Y, Vindivich D, Phillip JM, Wu PH, Wirtz D, Getzenberg RH. Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis. Journal of Cellular Physiology. 229: 362-73. PMID 23996089 DOI: 10.1002/Jcp.24458  0.4
2013 Bajpai S, Feng Y, Wirtz D, Longmore GD. β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths. Biophysical Journal. 105: 2289-300. PMID 24268141 DOI: 10.1016/J.Bpj.2013.09.044  1
2013 Gong J, Zhang D, Tseng Y, Li B, Wirtz D, Schafer BW. Form-finding model shows how cytoskeleton network stiffness is realized. Plos One. 8: e77417. PMID 24146992 DOI: 10.1371/Journal.Pone.0077417  0.64
2013 Dobrowsky TM, Rabi SA, Nedellec R, Daniels BR, Mullins JI, Mosier DE, Siliciano RF, Wirtz D. Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins. Scientific Reports. 3: 3014. PMID 24145278 DOI: 10.1038/Srep03014  1
2013 Guo Q, Phillip JM, Majumdar S, Wu PH, Chen J, Calderón-Colón X, Schein O, Smith BJ, Trexler MM, Wirtz D, Elisseeff JH. Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair. Biomaterials. 34: 9365-72. PMID 24041426 DOI: 10.1016/J.Biomaterials.2013.08.061  0.4
2013 Kim DH, Chambliss AB, Wirtz D. The multi-faceted role of the actin cap in cellular mechanosensation and mechanotransduction. Soft Matter. 9: 5516-5523. PMID 23930135 DOI: 10.1039/C3Sm50798J  1
2013 Giri A, Bajpai S, Trenton N, Jayatilaka H, Longmore GD, Wirtz D. The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4089-99. PMID 23796785 DOI: 10.1096/Fj.12-224352  1
2013 Stukalin EB, Aifuwa I, Kim JS, Wirtz D, Sun SX. Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells. Journal of the Royal Society, Interface / the Royal Society. 10: 20130325. PMID 23760298 DOI: 10.1098/Rsif.2013.0325  1
2013 Kim DH, Wirtz D. Predicting how cells spread and migrate: focal adhesion size does matter. Cell Adhesion & Migration. 7: 293-6. PMID 23628962 DOI: 10.4161/Cam.24804  1
2013 Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL. Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Research. 73: 3285-96. PMID 23539444 DOI: 10.1158/0008-5472.Can-12-3963  1
2013 Chambliss AB, Wu PH, Chen WC, Sun SX, Wirtz D. Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2667-76. PMID 23538711 DOI: 10.1096/Fj.12-227108  1
2013 Wirtz D. Interstitial friction greatly impacts membrane mechanics. Biophysical Journal. 104: 1217-8. PMID 23528079 DOI: 10.1016/J.Bpj.2013.02.003  1
2013 Konstantopoulos K, Wu PH, Wirtz D. Dimensional control of cancer cell migration. Biophysical Journal. 104: 279-80. PMID 23442847 DOI: 10.1016/J.Bpj.2012.12.016  1
2013 Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL. Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts. The Journal of Biological Chemistry. 288: 10819-29. PMID 23423382 DOI: 10.1074/Jbc.M112.442939  1
2013 Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Molecular Cancer Research : McR. 11: 456-66. PMID 23378577 DOI: 10.1158/1541-7786.Mcr-12-0629  1
2013 Lu Y, Chen JJ, Mu L, Xue Q, Wu Y, Wu PH, Li J, Vortmeyer AO, Miller-Jensen K, Wirtz D, Fan R. High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity. Analytical Chemistry. 85: 2548-56. PMID 23339603 DOI: 10.1021/Ac400082E  1
2013 Chambliss AB, Khatau SB, Erdenberger N, Robinson DK, Hodzic D, Longmore GD, Wirtz D. The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Scientific Reports. 3: 1087. PMID 23336069 DOI: 10.1038/Srep01087  1
2013 Chen WC, Wu PH, Phillip JM, Khatau SB, Choi JM, Dallas MR, Konstantopoulos K, Sun SX, Lee JS, Hodzic D, Wirtz D. Functional interplay between the cell cycle and cell phenotypes. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 523-34. PMID 23319145 DOI: 10.1039/C2Ib20246H  1
2013 Kim DH, Wirtz D. Focal adhesion size uniquely predicts cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1351-61. PMID 23254340 DOI: 10.1096/Fj.12-220160  1
2013 Chau E, Galloway JF, Nelson A, Breysse PN, Wirtz D, Searson PC, Sidhaye VK. Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro. Nanotoxicology. 7: 1143-51. PMID 22783847 DOI: 10.3109/17435390.2012.711862  1
2012 Raman PS, Alves CS, Wirtz D, Konstantopoulos K. Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen). Biophysical Journal. 103: 415-23. PMID 22947857 DOI: 10.1016/J.Bpj.2012.06.039  1
2012 Kim DH, Khatau SB, Feng Y, Walcott S, Sun SX, Longmore GD, Wirtz D. Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Scientific Reports. 2: 555. PMID 22870384 DOI: 10.1038/Srep00555  1
2012 Khatau SB, Bloom RJ, Bajpai S, Razafsky D, Zang S, Giri A, Wu PH, Marchand J, Celedon A, Hale CM, Sun SX, Hodzic D, Wirtz D. The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration. Scientific Reports. 2: 488. PMID 22761994 DOI: 10.1038/Srep00488  1
2012 Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wang TL, Wirtz D, Shih IeM. NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells. Cancer Research. 72: 4085-96. PMID 22761335 DOI: 10.1158/0008-5472.Can-12-0302  1
2012 Lee MH, Wu PH, Staunton JR, Ros R, Longmore GD, Wirtz D. Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer. Biophysical Journal. 102: 2731-41. PMID 22735523 DOI: 10.1016/J.Bpj.2012.05.005  1
2012 Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D. The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. Plos One. 7: e36689. PMID 22574215 DOI: 10.1371/Journal.Pone.0036689  1
2012 Dallas MR, Liu G, Chen WC, Thomas SN, Wirtz D, Huso DL, Konstantopoulos K. Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2648-56. PMID 22415308 DOI: 10.1096/Fj.12-203786  1
2012 Fraley SI, Feng Y, Giri A, Longmore GD, Wirtz D. Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nature Communications. 3: 719. PMID 22395610 DOI: 10.1038/Ncomms1711  1
2012 Wu PH, Hale CM, Chen WC, Lee JS, Tseng Y, Wirtz D. High-throughput ballistic injection nanorheology to measure cell mechanics. Nature Protocols. 7: 155-70. PMID 22222790 DOI: 10.1038/Nprot.2011.436  0.64
2012 Yap KL, Fraley SI, Shah PS, Wang F, Thiaville MM, Jinawath N, Nakayama K, Wang J, Brayton C, Bolon B, Gabrielson K, Wirtz D, Wang T, Shih I. Abstract LB-115: NAC1 is an actin binding protein essential for the cytokinesis of cancer cells and plays a role in the patterning of murine vertebral axis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-115  0.44
2012 Dallas MR, Liu G, Chen WC, Thomas SN, Wirtz D, Huso DL, Konstantopoulos K. Erratum: Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis (FASEB Journal (2012) 26 (2648-2656) DOI: 10.1096/fj.12- 203786) The Faseb Journal. 26. DOI: 10.1096/Fj.12-203786Err  0.48
2012 Wirtz D. Biophysics of molecular cell mechanics Comprehensive Biophysics. 7: 104-121. DOI: 10.1016/B978-0-12-374920-8.00708-6  1
2012 Cheung LSL, Raman PS, Wirtz D, Konstantopoulos K. Biophysics of selectin-mediated cell adhesion Comprehensive Biophysics. 7: 10-32. DOI: 10.1016/B978-0-12-374920-8.00703-7  1
2012 Wirtz D. Introduction Comprehensive Biophysics. 7: 1-1. DOI: 10.1016/B978-0-12-374920-8.00701-3  1
2011 Walcott S, Kim DH, Wirtz D, Sun SX. Nucleation and decay initiation are the stiffness-sensitive phases of focal adhesion maturation. Biophysical Journal. 101: 2919-28. PMID 22208190 DOI: 10.1016/J.Bpj.2011.11.010  0.88
2011 Hale CM, Chen WC, Khatau SB, Daniels BR, Lee JS, Wirtz D. SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization. Journal of Cell Science. 124: 4267-85. PMID 22193958 DOI: 10.1242/Jcs.091231  1
2011 Celedon A, Hale CM, Wirtz D. Magnetic manipulation of nanorods in the nucleus of living cells. Biophysical Journal. 101: 1880-6. PMID 22004741 DOI: 10.1016/J.Bpj.2011.09.008  1
2011 Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 16369-74. PMID 21911388 DOI: 10.1073/Pnas.1113483108  1
2011 Wirtz D, Konstantopoulos K, Searson PC. The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nature Reviews. Cancer. 11: 512-22. PMID 21701513 DOI: 10.1038/Nrc3080  1
2011 Raman PS, Alves CS, Wirtz D, Konstantopoulos K. Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer. Journal of Cell Science. 124: 1903-10. PMID 21558419 DOI: 10.1016/J.Bpj.2010.12.2820  1
2011 Kim DH, Wirtz D. Recapitulating cancer cell invasion in vitro. Proceedings of the National Academy of Sciences of the United States of America. 108: 6693-4. PMID 21490296 DOI: 10.1073/Pnas.1103983108  1
2011 Lee JS, Wirtz D. Physical oncology. Preface. Physical Biology. 8: 010301. PMID 21368347 DOI: 10.1088/1478-3975/8/1/010301  1
2011 Cheung LS, Raman PS, Balzer EM, Wirtz D, Konstantopoulos K. Biophysics of selectin-ligand interactions in inflammation and cancer. Physical Biology. 8: 015013. PMID 21301059 DOI: 10.1088/1478-3975/8/1/015013  1
2011 Wirtz D. Editor-in-Chief: Professor Denis Wirtz Cell Health and Cytoskeleton. 3: 1. DOI: 10.2147/CHC.S8916  1
2011 Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wirtz D, Wang T, Shih l. Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-B18  0.44
2011 Fraley SI, Feng Y, Wirtz D, Longmore GD. Reply: Reducing background fluorescence reveals adhesions in 3D matrices Nature Cell Biology. 13: 5-7. DOI: 10.1038/Ncb0111-5  1
2011 Dobrowsky TM, Wirtz D. Single-molecule analysis of cell-virus binding interactions Cell Signaling Reactions: Single-Molecular Kinetic Analysis. 153-166. DOI: 10.1007/978-90-481-9864-1_7  1
2010 Khatau SB, Kim DH, Hale CM, Bloom RJ, Wirtz D. The perinuclear actin cap in health and disease. Nucleus (Austin, Tex.). 1: 337-42. PMID 21327082 DOI: 10.4161/Nucl.1.4.12331  1
2010 Daniels BR, Hale CM, Khatau SB, Kusuma S, Dobrowsky TM, Gerecht S, Wirtz D. Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells. Biophysical Journal. 99: 3563-70. PMID 21112280 DOI: 10.1016/J.Bpj.2010.10.007  1
2010 Mali P, Wirtz D, Searson PC. Interplay of RhoA and motility in the programmed spreading of daughter cells postmitosis. Biophysical Journal. 99: 3526-34. PMID 21112276 DOI: 10.1016/J.Bpj.2010.10.006  1
2010 Celedon A, Wirtz D, Sun S. Torsional mechanics of DNA are regulated by small-molecule intercalation. The Journal of Physical Chemistry. B. 114: 16929-35. PMID 21090816 DOI: 10.1021/Jp107541Q  1
2010 Dajkovic A, Pichoff S, Lutkenhaus J, Wirtz D. Cross-linking FtsZ polymers into coherent Z rings. Molecular Microbiology. 78: 651-68. PMID 20969647 DOI: 10.1111/J.1365-2958.2010.07352.X  1
2010 Wirtz D, Khatau SB. Protein filaments: Bundles from boundaries. Nature Materials. 9: 788-90. PMID 20864937 DOI: 10.1038/Nmat2868  1
2010 Stahl PJ, Romano NH, Wirtz D, Yu SM. PEG-based hydrogels with collagen mimetic peptide-mediated and tunable physical cross-links. Biomacromolecules. 11: 2336-44. PMID 20715762 DOI: 10.1021/Bm100465Q  1
2010 Dobrowsky TM, Daniels BR, Siliciano RF, Sun SX, Wirtz D. Organization of cellular receptors into a nanoscale junction during HIV-1 adhesion. Plos Computational Biology. 6: e1000855. PMID 20657663 DOI: 10.1371/Journal.Pcbi.1000855  1
2010 Daniels BR, Dobrowsky TM, Perkins EM, Sun SX, Wirtz D. MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion. Development (Cambridge, England). 137: 2579-85. PMID 20627961 DOI: 10.1242/Dev.051326  1
2010 Wildt B, Wirtz D, Searson PC. Triggering cell detachment from patterned electrode arrays by programmed subcellular release. Nature Protocols. 5: 1273-80. PMID 20595956 DOI: 10.1038/Nprot.2010.42  1
2010 Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, Wirtz D. A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nature Cell Biology. 12: 598-604. PMID 20473295 DOI: 10.1038/Ncb2062  1
2010 Esue O, Rupprecht L, Sun SX, Wirtz D. Dynamics of the bacterial intermediate filament crescentin in vitro and in vivo. Plos One. 5: e8855. PMID 20140233 DOI: 10.1371/Journal.Pone.0008855  1
2009 Khatau SB, Hale CM, Stewart-Hutchinson PJ, Patel MS, Stewart CL, Searson PC, Hodzic D, Wirtz D. A perinuclear actin cap regulates nuclear shape. Proceedings of the National Academy of Sciences of the United States of America. 106: 19017-22. PMID 19850871 DOI: 10.1073/Pnas.0908686106  1
2009 Hale CM, Sun SX, Wirtz D. Resolving the role of actoymyosin contractility in cell microrheology. Plos One. 4: e7054. PMID 19756147 DOI: 10.1371/Journal.Pone.0007054  1
2009 Bajpai S, Feng Y, Krishnamurthy R, Longmore GD, Wirtz D. Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. The Journal of Biological Chemistry. 284: 18252-9. PMID 19458087 DOI: 10.1074/Jbc.M109.000661  1
2009 Wirtz D. Particle-tracking microrheology of living cells: principles and applications. Annual Review of Biophysics. 38: 301-26. PMID 19416071 DOI: 10.1146/Annurev.Biophys.050708.133724  1
2009 Celedon A, Nodelman IM, Wildt B, Dewan R, Searson P, Wirtz D, Bowman GD, Sun SX. Magnetic tweezers measurement of single molecule torque. Nano Letters. 9: 1720-5. PMID 19301859 DOI: 10.1021/Nl900631W  1
2009 Daniels BR, Perkins EM, Dobrowsky TM, Sun SX, Wirtz D. Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion. The Journal of Cell Biology. 184: 473-9. PMID 19221192 DOI: 10.1083/Jcb.200809077  0.64
2009 Esue O, Tseng Y, Wirtz D. Alpha-actinin and filamin cooperatively enhance the stiffness of actin filament networks. Plos One. 4: e4411. PMID 19198659 DOI: 10.1371/Journal.Pone.0004411  1
2009 Wildt B, Wirtz D, Searson PC. Programmed subcellular release for studying the dynamics of cell detachment. Nature Methods. 6: 211-3. PMID 19182793 DOI: 10.1038/Nmeth.1299  1
2009 Lai SK, Wang YY, Cone R, Wirtz D, Hanes J. Altering mucus rheology to "solidify" human mucus at the nanoscale. Plos One. 4: e4294. PMID 19173002 DOI: 10.1371/Journal.Pone.0004294  1
2009 Lai SK, Wang YY, Wirtz D, Hanes J. Micro- and macrorheology of mucus. Advanced Drug Delivery Reviews. 61: 86-100. PMID 19166889 DOI: 10.1016/J.Addr.2008.09.012  1
2009 Lan G, Daniels BR, Dobrowsky TM, Wirtz D, Sun SX. Condensation of FtsZ filaments can drive bacterial cell division. Proceedings of the National Academy of Sciences of the United States of America. 106: 121-6. PMID 19116281 DOI: 10.1073/Pnas.0807963106  0.64
2009 Galloway JF, Park J, Lee KH, Wirtz D, Searson PC. Exploiting nucleation and growth in the synthesis and electrical passivation of CdSe quantum dots Science of Advanced Materials. 1: 93-100. DOI: 10.1166/Sam.2009.1014  1
2008 Thompson MS, Wirtz D. Chapter 18: Sensing cytoskeletal mechanics by ballistic intracellular nanorheology (BIN) coupled with cell transfection. Methods in Cell Biology. 89: 467-86. PMID 19118687 DOI: 10.1016/S0091-679X(08)00618-3  1
2008 Dobrowsky TM, Panorchan P, Konstantopoulos K, Wirtz D. Chapter 15: Live-cell single-molecule force spectroscopy. Methods in Cell Biology. 89: 411-32. PMID 19118684 DOI: 10.1016/S0091-679X(08)00615-8  1
2008 Bajpai S, Correia J, Feng Y, Figueiredo J, Sun SX, Longmore GD, Suriano G, Wirtz D. {alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proceedings of the National Academy of Sciences of the United States of America. 105: 18331-6. PMID 19017792 DOI: 10.1073/Pnas.0806783105  1
2008 Esue O, Harris ES, Higgs HN, Wirtz D. The filamentous actin cross-linking/bundling activity of mammalian formins. Journal of Molecular Biology. 384: 324-34. PMID 18835565 DOI: 10.1016/J.Jmb.2008.09.043  1
2008 Hale CM, Shrestha AL, Khatau SB, Stewart-Hutchinson PJ, Hernandez L, Stewart CL, Hodzic D, Wirtz D. Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. Biophysical Journal. 95: 5462-75. PMID 18790843 DOI: 10.1529/Biophysj.108.139428  1
2008 Bloom RJ, George JP, Celedon A, Sun SX, Wirtz D. Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking. Biophysical Journal. 95: 4077-88. PMID 18641063 DOI: 10.1529/Biophysj.108.132738  1
2008 Lan G, Dajkovic A, Wirtz D, Sun SX. Polymerization and bundling kinetics of FtsZ filaments. Biophysical Journal. 95: 4045-56. PMID 18621825 DOI: 10.1529/Biophysj.108.132837  1
2008 Dobrowsky TM, Zhou Y, Sun SX, Siliciano RF, Wirtz D. Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution. Journal of Virology. 82: 7022-33. PMID 18480458 DOI: 10.1128/Jvi.00053-08  1
2008 Zhou X, Rowe RG, Hiraoka N, George JP, Wirtz D, Mosher DF, Virtanen I, Chernousov MA, Weiss SJ. Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. Genes & Development. 22: 1231-43. PMID 18451110 DOI: 10.1101/Gad.1643308  1
2008 Stewart-Hutchinson PJ, Hale CM, Wirtz D, Hodzic D. Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Experimental Cell Research. 314: 1892-905. PMID 18396275 DOI: 10.1016/J.Yexcr.2008.02.022  1
2008 Dajkovic A, Lan G, Sun SX, Wirtz D, Lutkenhaus J. MinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZ. Current Biology : Cb. 18: 235-44. PMID 18291654 DOI: 10.1016/J.Cub.2008.01.042  1
2007 Lee JS, Hale CM, Panorchan P, Khatau SB, George JP, Tseng Y, Stewart CL, Hodzic D, Wirtz D. Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration. Biophysical Journal. 93: 2542-52. PMID 17631533 DOI: 10.1529/Biophysj.106.102426  1
2007 Panorchan P, Lee JS, Daniels BR, Kole TP, Tseng Y, Wirtz D. Probing cellular mechanical responses to stimuli using ballistic intracellular nanorheology. Methods in Cell Biology. 83: 115-40. PMID 17613307 DOI: 10.1016/S0091-679X(07)83006-8  1
2006 Esue O, Carson AA, Tseng Y, Wirtz D. A direct interaction between actin and vimentin filaments mediated by the tail domain of vimentin. The Journal of Biological Chemistry. 281: 30393-9. PMID 16901892 DOI: 10.1074/Jbc.M605452200  1
2006 Panorchan P, Lee JS, Kole TP, Tseng Y, Wirtz D. Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix. Biophysical Journal. 91: 3499-507. PMID 16891369 DOI: 10.1529/Biophysj.106.084988  1
2006 Lee JS, Panorchan P, Hale CM, Khatau SB, Kole TP, Tseng Y, Wirtz D. Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow. Journal of Cell Science. 119: 1760-8. PMID 16636071 DOI: 10.1242/Jcs.02899  1
2006 Daniels BR, Masi BC, Wirtz D. Probing single-cell micromechanics in vivo: the microrheology of C. elegans developing embryos. Biophysical Journal. 90: 4712-9. PMID 16581841 DOI: 10.1529/Biophysj.105.080606  1
2006 Panorchan P, George JP, Wirtz D. Probing intercellular interactions between vascular endothelial cadherin pairs at single-molecule resolution and in living cells. Journal of Molecular Biology. 358: 665-74. PMID 16540120 DOI: 10.1016/J.Jmb.2006.02.021  1
2006 Esue O, Wirtz D, Tseng Y. GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB. Journal of Bacteriology. 188: 968-76. PMID 16428401 DOI: 10.1128/Jb.188.3.968-976.2006  1
2006 Panorchan P, Thompson MS, Davis KJ, Tseng Y, Konstantopoulos K, Wirtz D. Single-molecule analysis of cadherin-mediated cell-cell adhesion. Journal of Cell Science. 119: 66-74. PMID 16371651 DOI: 10.1242/Jcs.02719  1
2006 Sun SX, Wirtz D. Mechanics of enveloped virus entry into host cells. Biophysical Journal. 90: L10-2. PMID 16284274 DOI: 10.1529/Biophysj.105.074203  1
2006 Atilgan E, Wirtz D, Sun SX. Mechanics and dynamics of actin-driven thin membrane protrusions. Biophysical Journal. 90: 65-76. PMID 16214866 DOI: 10.1529/Biophysj.105.071480  1
2005 Chang MI, Panorchan P, Dobrowsky TM, Tseng Y, Wirtz D. Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. Journal of Virology. 79: 14748-55. PMID 16282475 DOI: 10.1128/Jvi.79.23.14748-14755.2005  1
2005 Esue O, Tseng Y, Wirtz D. Mechanical shear can accelerate the gelation of actin filament networks. Physical Review Letters. 95: 048301. PMID 16090845 DOI: 10.1103/Physrevlett.95.048301  1
2005 Atilgan E, Wirtz D, Sun SX. Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells. Biophysical Journal. 89: 3589-602. PMID 16085776 DOI: 10.1529/Biophysj.105.065383  1
2005 Tseng Y, Kole TP, Lee JS, Fedorov E, Almo SC, Schafer BW, Wirtz D. How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response. Biochemical and Biophysical Research Communications. 334: 183-92. PMID 15992772 DOI: 10.1016/J.Bbrc.2005.05.205  1
2005 Esue O, Tseng Y, Wirtz D. The rapid onset of elasticity during the assembly of the bacterial cell-division protein FtsZ. Biochemical and Biophysical Research Communications. 333: 508-16. PMID 15950938 DOI: 10.1016/J.Bbrc.2005.05.152  1
2005 Gupton SL, Anderson KL, Kole TP, Fischer RS, Ponti A, Hitchcock-DeGregori SE, Danuser G, Fowler VM, Wirtz D, Hanein D, Waterman-Storer CM. Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. The Journal of Cell Biology. 168: 619-31. PMID 15716379 DOI: 10.1083/Jcb.200406063  1
2005 Lee JS, Chang MI, Tseng Y, Wirtz D. Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Molecular Biology of the Cell. 16: 871-80. PMID 15548602 DOI: 10.1091/Mbc.E03-12-0910  1
2005 Esue O, Cordero M, Wirtz D, Tseng Y. The assembly of MreB, a prokaryotic homolog of actin. The Journal of Biological Chemistry. 280: 2628-35. PMID 15548516 DOI: 10.1074/Jbc.M410298200  1
2005 Kole TP, Tseng Y, Jiang I, Katz JL, Wirtz D. Intracellular mechanics of migrating fibroblasts. Molecular Biology of the Cell. 16: 328-38. PMID 15483053 DOI: 10.1091/Mbc.E04-06-0485  1
2005 Wirtz D. Live-cell microrheology Aiche Annual Meeting, Conference Proceedings. 1132.  1
2004 Tseng Y, Wirtz D. Dendritic branching and homogenization of actin networks mediated by arp2/3 complex. Physical Review Letters. 93: 258104. PMID 15697951 DOI: 10.1103/Physrevlett.93.258104  1
2004 Kole TP, Tseng Y, Wirtz D. Intracellular microrheology as a tool for the measurement of the local mechanical properties of live cells. Methods in Cell Biology. 78: 45-64. PMID 15646615 DOI: 10.1016/S0091-679X(04)78003-6  1
2004 Panorchan P, Wirtz D, Tseng Y. Structure-function relationship of biological gels revealed by multiple-particle tracking and differential interference contrast microscopy: the case of human lamin networks. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 70: 041906. PMID 15600434 DOI: 10.1103/Physreve.70.041906  1
2004 Panorchan P, Schafer BW, Wirtz D, Tseng Y. Nuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear lamina. The Journal of Biological Chemistry. 279: 43462-7. PMID 15292200 DOI: 10.1074/Jbc.M402474200  1
2004 Klein MG, Shi W, Ramagopal U, Tseng Y, Wirtz D, Kovar DR, Staiger CJ, Almo SC. Structure of the actin crosslinking core of fimbrin. Structure (London, England : 1993). 12: 999-1013. PMID 15274920 DOI: 10.1016/J.Str.2004.04.010  1
2004 Dawson M, Krauland E, Wirtz D, Hanes J. Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnology Progress. 20: 851-7. PMID 15176891 DOI: 10.1021/Bp0342553  1
2004 Hanley WD, Wirtz D, Konstantopoulos K. Distinct kinetic and mechanical properties govern selectin-leukocyte interactions. Journal of Cell Science. 117: 2503-11. PMID 15159451 DOI: 10.1242/Jcs.01088  1
2004 Kole TP, Tseng Y, Huang L, Katz JL, Wirtz D. Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation. Molecular Biology of the Cell. 15: 3475-84. PMID 15146061 DOI: 10.1091/Mbc.E04-03-0218  1
2004 Tseng Y, Lee JS, Kole TP, Jiang I, Wirtz D. Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking. Journal of Cell Science. 117: 2159-67. PMID 15090601 DOI: 10.1242/Jcs.01073  1
2004 Heidemann SR, Wirtz D. Towards a regional approach to cell mechanics. Trends in Cell Biology. 14: 160-6. PMID 15066633 DOI: 10.1016/J.Tcb.2004.02.003  1
2004 Suh J, Wirtz D, Hanes J. Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking. Biotechnology Progress. 20: 598-602. PMID 15059007 DOI: 10.1021/Bp034251Y  1
2004 Tseng Y, An KM, Esue O, Wirtz D. The bimodal role of filamin in controlling the architecture and mechanics of F-actin networks. The Journal of Biological Chemistry. 279: 1819-26. PMID 14594947 DOI: 10.1074/Jbc.M306090200  1
2004 Dawson M, Wirtz D, Hanes J. Microscopic viscoelasticity of CF sputum determined by high-resolution nanoparticle tracking Aiche Annual Meeting, Conference Proceedings. 1315-1316.  1
2004 Dawson M, Wirtz D, Hanes J. Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking Aiche Annual Meeting, Conference Proceedings. 6345.  1
2003 Dawson M, Wirtz D, Hanes J. Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport. The Journal of Biological Chemistry. 278: 50393-401. PMID 13679362 DOI: 10.1074/Jbc.M309026200  1
2003 Konstantopoulos K, Hanley WD, Wirtz D. Receptor-ligand binding: 'catch' bonds finally caught. Current Biology : Cb. 13: R611-3. PMID 12906816 DOI: 10.1016/S0960-9822(03)00529-3  1
2003 Yamada S, Wirtz D, Coulombe PA. The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. Journal of Structural Biology. 143: 45-55. PMID 12892725 DOI: 10.1016/S1047-8477(03)00101-1  1
2003 Suh J, Wirtz D, Hanes J. Efficient active transport of gene nanocarriers to the cell nucleus. Proceedings of the National Academy of Sciences of the United States of America. 100: 3878-82. PMID 12644705 DOI: 10.1073/Pnas.0636277100  1
2003 Li HY, Wirtz D, Zheng Y. A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. The Journal of Cell Biology. 160: 635-44. PMID 12604592 DOI: 10.1083/Jcb.200211004  1
2003 Hanley W, McCarty O, Jadhav S, Tseng Y, Wirtz D, Konstantopoulos K. Single molecule characterization of P-selectin/ligand binding. The Journal of Biological Chemistry. 278: 10556-61. PMID 12522146 DOI: 10.1074/Jbc.M213233200  0.64
2003 Zhou Y, Wirtz D, Chirikjian GS. Determining the Gaussian probability distribution of the best-fit ellipsoid of revolution for a polymer chain from planar projections Inverse Problems. 19: 725-738. DOI: 10.1088/0266-5611/19/3/315  1
2002 Tseng Y, Kole TP, Wirtz D. Micromechanical mapping of live cells by multiple-particle-tracking microrheology. Biophysical Journal. 83: 3162-76. PMID 12496086 DOI: 10.1016/S0006-3495(02)75319-8  1
2002 Goodman A, Tseng Y, Wirtz D. Effect of length, topology, and concentration on the microviscosity and microheterogeneity of DNA solutions. Journal of Molecular Biology. 323: 199-215. PMID 12381315 DOI: 10.1016/S0022-2836(02)00893-8  1
2002 Rahman A, Tseng Y, Wirtz D. Micromechanical coupling between cell surface receptors and RGD peptides. Biochemical and Biophysical Research Communications. 296: 771-8. PMID 12176050 DOI: 10.1016/S0006-291X(02)00903-8  1
2002 Tseng Y, Schafer BW, Almo SC, Wirtz D. Functional synergy of actin filament cross-linking proteins. The Journal of Biological Chemistry. 277: 25609-16. PMID 12006593 DOI: 10.1074/Jbc.M202609200  1
2002 Tseng Y, An KM, Wirtz D. Microheterogeneity controls the rate of gelation of actin filament networks. The Journal of Biological Chemistry. 277: 18143-50. PMID 11889122 DOI: 10.1074/Jbc.M110868200  1
2002 Xu J, Tseng Y, Carriere CJ, Wirtz D. Microheterogeneity and microrheology of wheat gliadin suspensions studied by multiple-particle tracking. Biomacromolecules. 3: 92-9. PMID 11866560 DOI: 10.1021/Bm015586B  1
2002 Yamada S, Wirtz D, Coulombe PA. Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Molecular Biology of the Cell. 13: 382-91. PMID 11809846 DOI: 10.1091/Mbc.01-10-0522  1
2002 Tseng Y, Kole TP, Lee SHJ, Wirtz D. Local dynamics and viscoelastic properties of cell biological systems Current Opinion in Colloid and Interface Science. 7: 210-217. DOI: 10.1016/S1359-0294(02)00050-X  1
2002 Suh J, Wirtz D, Hanes J. Real-time quantitation of intracellular polycation/DNA nanocomplex transport: Evidence for directed motion Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 548-549.  1
2001 Tseng Y, Wirtz D. Mechanics and multiple-particle tracking microheterogeneity of α-actinin-cross-linked actin filament networks Biophysical Journal. 81: 1643-1656. PMID 11509377 DOI: 10.1016/S0006-3495(01)75818-3  1
2001 Tseng Y, Fedorov E, McCaffery JM, Almo SC, Wirtz D. Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: A comparison with α-actinin Journal of Molecular Biology. 310: 351-366. PMID 11428894 DOI: 10.1006/Jmbi.2001.4716  1
2001 Ma L, Yamada S, Wirtz D, Coulombe PA. A 'hot-spot' mutation alters the mechanical properties of keratin filament networks. Nature Cell Biology. 3: 503-6. PMID 11331879 DOI: 10.1038/35074576  1
2001 Wirtz D. Regulation of cell-matrix adhesion strength by cytoskeleton re-organization American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 659-660.  1
2000 Haber C, Ruiz SA, Wirtz D. Shape anisotropy of a single random-walk polymer Proceedings of the National Academy of Sciences of the United States of America. 97: 10792-10795. PMID 10984514 DOI: 10.1073/Pnas.190320097  1
2000 Haber C, Wirtz D. Shear-induced assembly of λ-phage DNA Biophysical Journal. 79: 1530-1536. PMID 10969014 DOI: 10.1016/S0006-3495(00)76404-6  1
2000 Xu J, Tseng Y, Wirtz D. Strain hardening of actin filament networks: Regulation by the dynamic cross-linking protein α-actinin Journal of Biological Chemistry. 275: 35886-35892. PMID 10954703 DOI: 10.1074/Jbc.M002377200  1
2000 Apgar J, Tseng Y, Fedorov E, Herwig MB, Almo SC, Wirtz D. Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles Biophysical Journal. 79: 1095-1106. PMID 10920039 DOI: 10.1016/S0006-3495(00)76363-6  1
2000 Yamada S, Wirtz D, Kuo SC. Mechanics of living cells measured by laser tracking microrheology Biophysical Journal. 78: 1736-1747. PMID 10733956 DOI: 10.1016/S0006-3495(00)76725-7  1
2000 Haber C, Wirtz D. Magnetic tweezers for DNA micromanipulation Review of Scientific Instruments. 71: 4561-4570. DOI: 10.1063/1.1326056  1
1999 Ma L, Xu J, Coulombe PA, Wirtz D. Keratin filament suspensions show unique micromechanical properties. The Journal of Biological Chemistry. 274: 19145-51. PMID 10383419 DOI: 10.1074/Jbc.274.27.19145  1
1999 LeDuc P, Haber C, Bao G, Wirtz D. Dynamics of individual flexible polymers in a shear flow Nature. 399: 564-566. PMID 10376595 DOI: 10.1038/21148  1
1999 Palmer A, Mason TG, Xu J, Kuo SC, Wirtz D. Diffusing wave spectroscopy microrheology of actin filament networks Biophysical Journal. 76: 1063-1071. PMID 9916038 DOI: 10.1016/S0006-3495(99)77271-1  1
1999 Wirtz D, Evans E. Materials science of the cell Mrs Bulletin. 24: 19-20. DOI: 10.1557/S0883769400053215  1
1999 Rufener K, Palmer A, Xu J, Wirtz D. High-frequency dynamics and microrheology of macromolecular solutions probed by diffusing wave spectroscopy: the case of concentrated solutions of F-actin Journal of Non-Newtonian Fluid Mechanics. 82: 303-314. DOI: 10.1016/S0377-0257(98)00169-4  1
1999 LeDuc P, Tsourkas A, Lavan D, Wirtz D, Bao G. Visualization of the real-time dynamics of individual deoxyribonucleic acid molecules under shear strain American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 87-88.  1
1998 Petka WA, Harden JL, McGrath KP, Wirtz D, Tirrell DA. Reversible hydrogels from self-assembling artificial proteins. Science (New York, N.Y.). 281: 389-92. PMID 9665877 DOI: 10.1126/Science.281.5375.389  1
1998 Xu J, Wirtz D, Pollard TD. Dynamic cross-linking by α-actinin determines the mechanical properties of actin filament networks Journal of Biological Chemistry. 273: 9570-9576. PMID 9545287 DOI: 10.1074/Jbc.273.16.9570  1
1998 Xu J, Palmer A, Wirtz D. Rheology and microrheology of semiflexible polymer solutions: Actin filament networks Macromolecules. 31: 6486-6492. DOI: 10.1021/Ma9717754  1
1998 Mason TG, Dhople A, Wirtz D. Linear viscoelastic moduli of concentrated DNA solutions Macromolecules. 31: 3600-3603. DOI: 10.1021/Ma970564W  1
1998 Silva AS, Wirtz D. Dominant diffusing mode in the self-similar phase separation of a magnetic suspension in a magnetic field Langmuir. 14: 578-581. DOI: 10.1021/La970963K  1
1998 Xu J, Viasnoff V, Wirtz D. Compliance of actin filament networks measured by particle-tracking microrheology and diffusing wave spectroscopy Rheologica Acta. 37: 387-398. DOI: 10.1007/S003970050125  1
1998 Palmer A, Xu J, Wirtz D. High-frequency viscoelasticity of crosslinked actin filament networks measured by diffusing wave spectroscopy Rheologica Acta. 37: 97-106. DOI: 10.1007/S003970050095  1
1998 Palmer A, Cha B, Wirtz D. Structure and dynamics of actin filament solutions in the presence of latrunculin A Journal of Polymer Science, Part B: Polymer Physics. 36: 3007-3015. DOI: 10.1002/(Sici)1099-0488(199812)36:17<3007::Aid-Polb1>3.0.Co;2-D  1
1997 Mason TG, Dhople A, Wirtz D. Concentrated DNA rheology and microrheology Materials Research Society Symposium - Proceedings. 463: 153-158. DOI: 10.1557/Proc-463-153  1
1997 Mason TG, Ganesan K, Van Zanten JH, Wirtz D, Kuo SC. Particle tracking microrheology of complex fluids Physical Review Letters. 79: 3282-3285. DOI: 10.1103/Physrevlett.79.3282  1
1996 Silva AS, Bond R, Plouraboué F, Wirtz D. Fluctuation dynamics of a single magnetic chain Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 54: 5502-5510. DOI: 10.1103/Physreve.54.5502  1
1995 Wirtz D. Direct measurement of the transport properties of a single DNA molecule Physical Review Letters. 75: 2436-2439. DOI: 10.1103/Physrevlett.75.2436  1
1995 Wirtz D, Fermigier M. Periodic structures and substructures in magnetic suspensions Langmuir. 11: 398-400. DOI: 10.1021/La00002A004  1
1994 Wirtz D, Fermigier M. One-dimensional patterns and wavelength selection in magnetic fluids Physical Review Letters. 72: 2294-2297. DOI: 10.1103/Physrevlett.72.2294  1
1994 Wirtz D. Flow-induced scattering peak in the structure factor of polymer solutions Physical Review E. 50. DOI: 10.1103/Physreve.50.R1755  1
1994 Wirtz D, Werner DE, Fuller GG. Structure and optical anisotropies of critical polymer solutions in electric fields The Journal of Chemical Physics. 101: 1679-1686. DOI: 10.1063/1.467789  1
1993 Wirtz D, Fuller GG. Phase transitions induced by electric fields in near-critical polymer solutions Physical Review Letters. 71: 2236-2239. DOI: 10.1103/Physrevlett.71.2236  1
1992 Wirtz D, Berend K, Fuller GG. Electric-field-induced structure in polymer solutions near the critical point Macromolecules. 25: 7234-7246. DOI: 10.1021/Ma00052A027  1
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