| Year |
Citation |
Score |
| 2025 |
Seshadri K, Abad AND, Nagasawa KK, Yost KM, Johnson CW, Dror MJ, Tang Y. Synthetic Biology in Natural Product Biosynthesis. Chemical Reviews. PMID 40116601 DOI: 10.1021/acs.chemrev.4c00567 |
0.334 |
|
| 2024 |
Zhang Y, Wu L, Kerr TA, Garg NK, Tang Y. Fragment-Guided Genome Mining of Octacyclic Cyclophane Alkaloids from Fungi. Journal of the American Chemical Society. PMID 39140852 DOI: 10.1021/jacs.4c06734 |
0.365 |
|
| 2024 |
Dror MJ, Misa J, Yee DA, Chu AM, Yu RK, Chan BB, Aoyama LS, Chaparala AP, O'Connor SE, Tang Y. Engineered biosynthesis of plant heteroyohimbine and corynantheine alkaloids in Saccharomyces cerevisiae. Journal of Industrial Microbiology & Biotechnology. 51. PMID 38140980 DOI: 10.1093/jimb/kuad047 |
0.303 |
|
| 2023 |
Sato M, Sakano S, Nakahara M, Tamura Y, Hara K, Hashimoto H, Tang Y, Watanabe K. Uncommon Arrangement of Self-resistance Allows Biosynthesis of de novo Purine Biosynthesis Inhibitor that Acts as an Immunosuppressor. Journal of the American Chemical Society. PMID 38051581 DOI: 10.1021/jacs.3c09600 |
0.42 |
|
| 2023 |
Niwa K, Ohashi M, Xie K, Chiang CY, Jamieson CS, Sato M, Watanabe K, Liu F, Houk KN, Tang Y. Biosynthesis of Polycyclic Natural Products from Conjugated Polyenes via Tandem Isomerization and Pericyclic Reactions. Journal of the American Chemical Society. 145: 13520-13525. PMID 37310230 DOI: 10.1021/jacs.3c02380 |
0.766 |
|
| 2023 |
Jenner M, Hai Y, Nguyen HH, Passmore M, Skyrud W, Kim J, Garg NK, Zhang W, Ogorzalek Loo RR, Tang Y. Elucidating the molecular programming of a nonlinear non-ribosomal peptide synthetase responsible for fungal siderophore biosynthesis. Nature Communications. 14: 2832. PMID 37198174 DOI: 10.1038/s41467-023-38484-8 |
0.623 |
|
| 2023 |
Zhang Y, Go EB, Perlatti B, Wu L, Bills GF, Ohashi M, Tang Y. Biosynthesis of AS2077715 and Funiculosin: Pathway Reconstitution and Identification of Enzymes that Form the All- Cyclopentanetetraol Moiety. Journal of the American Chemical Society. 145: 6643-6647. PMID 36920241 DOI: 10.1021/jacs.3c01681 |
0.321 |
|
| 2023 |
Ohashi M, Tan D, Lu J, Jamieson CS, Kanayama D, Zhou J, Houk KN, Tang Y. Enzymatic Decalin Formation in Natural Product Biosynthesis. Journal of the American Chemical Society. PMID 36723171 DOI: 10.1021/jacs.2c12854 |
0.738 |
|
| 2023 |
Yee DA, Niwa K, Perlatti B, Chen M, Li Y, Tang Y. Genome mining for unknown-unknown natural products. Nature Chemical Biology. PMID 36702957 DOI: 10.1038/s41589-022-01246-6 |
0.375 |
|
| 2022 |
Chiang CY, Ohashi M, Tang Y. Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining. Natural Product Reports. PMID 36125308 DOI: 10.1039/d2np00050d |
0.311 |
|
| 2022 |
Tararina MA, Yee DA, Tang Y, Christianson DW. Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C-N Bond-Forming Reaction of Flavunoidine Biosynthesis. Biochemistry. 61: 2014-2024. PMID 36037799 DOI: 10.1021/acs.biochem.2c00335 |
0.551 |
|
| 2022 |
Sun Z, Jamieson CS, Ohashi M, Houk KN, Tang Y. Discovery and characterization of a terpene biosynthetic pathway featuring a norbornene-forming Diels-Alderase. Nature Communications. 13: 2568. PMID 35546152 DOI: 10.1038/s41467-022-30288-6 |
0.748 |
|
| 2022 |
Jamieson CS, Ohashi M, Houk KN, Tang Y. Computational Prediction and Experimental Validation of a Bridged Cation Intermediate in Akanthomycin Biosynthesis. Journal of the American Chemical Society. 144: 5280-5283. PMID 35297629 DOI: 10.1021/jacs.2c02288 |
0.723 |
|
| 2022 |
Cheng W, Chen M, Ohashi M, Tang Y. Biosynthesis of Terpenoid-Pyrrolobenzoxazine Hybrid Natural Product CJ-12662. Angewandte Chemie (International Ed. in English). PMID 35075754 DOI: 10.1002/anie.202116928 |
0.325 |
|
| 2021 |
Sato M, Kishimoto S, Yokoyama M, Jamieson CS, Narita K, Maeda N, Hara K, Hashimoto H, Tsunematsu Y, Houk KN, Tang Y, Watanabe K. Catalytic mechanism and -to- selectivity reversion of an octalin-forming natural Diels-Alderase. Nature Catalysis. 4: 223-232. PMID 35873532 DOI: 10.1038/s41929-021-00577-2 |
0.788 |
|
| 2021 |
Okorafor IC, Chen M, Tang Y. High-Titer Production of Olivetolic Acid and Analogs in Engineered Fungal Host Using a Nonplant Biosynthetic Pathway. Acs Synthetic Biology. PMID 34415146 DOI: 10.1021/acssynbio.1c00309 |
0.321 |
|
| 2021 |
Liu M, Ohashi M, Hung YS, Scherlach K, Watanabe K, Hertweck C, Tang Y. AoiQ Catalyzes Geminal Dichlorination of 1,3-Diketone Natural Products. Journal of the American Chemical Society. PMID 33957045 DOI: 10.1021/jacs.1c02868 |
0.531 |
|
| 2021 |
Jamieson CS, Misa J, Tang Y, Billingsley JM. Biosynthesis and synthetic biology of psychoactive natural products. Chemical Society Reviews. PMID 33908526 DOI: 10.1039/d1cs00065a |
0.75 |
|
| 2021 |
Ohashi M, Kakule TB, Tang MC, Jamieson CS, Liu M, Zhao YL, Houk KN, Tang Y. Biosynthesis of Cyclophane-Containing Hirsutellone Family of Fungal Natural Products. Journal of the American Chemical Society. PMID 33834778 DOI: 10.1021/jacs.1c00098 |
0.747 |
|
| 2020 |
Hai Y, Jenner M, Tang Y. Fungal siderophore biosynthesis catalysed by an iterative nonribosomal peptide synthetase. Chemical Science. 11: 11525-11530. PMID 34094397 DOI: 10.1039/d0sc03627g |
0.567 |
|
| 2020 |
Yan Y, Zang X, Jamieson CS, Lin HC, Houk KN, Zhou J, Tang Y. Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance. Chemical Science. 11: 9554-9562. PMID 34094220 DOI: 10.1039/d0sc03805a |
0.692 |
|
| 2020 |
Zhang Z, Tamura Y, Tang M, Qiao T, Sato M, Otsu Y, Sasamura S, Taniguchi M, Watanabe K, Tang Y. Biosynthesis of the Immunosuppressant (-)-FR901483. Journal of the American Chemical Society. PMID 33372776 DOI: 10.1021/jacs.0c12352 |
0.369 |
|
| 2020 |
Gao DW, Jamieson CS, Wang G, Yan Y, Zhou J, Houk KN, Tang Y. A Polyketide Cyclase That Forms Medium-Ring Lactones. Journal of the American Chemical Society. PMID 33351624 DOI: 10.1021/jacs.0c11226 |
0.808 |
|
| 2020 |
Hai Y, Chen M, Huang A, Tang Y. Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids. Journal of the American Chemical Society. PMID 33155797 DOI: 10.1021/jacs.0c09352 |
0.592 |
|
| 2020 |
Ohashi M, Jamieson CS, Cai Y, Tan D, Kanayama D, Tang MC, Anthony SM, Chari JV, Barber JS, Picazo E, Kakule TB, Cao S, Garg NK, Zhou J, Houk KN, ... Tang Y, et al. An enzymatic Alder-ene reaction. Nature. 586: 64-69. PMID 32999480 DOI: 10.1038/s41586-020-2743-5 |
0.706 |
|
| 2020 |
Zhang Z, Qiao T, Watanabe K, Tang Y. Concise biosynthesis of phenylfuropyridones from fungi. Angewandte Chemie (International Ed. in English). PMID 32779306 DOI: 10.1002/Anie.202008321 |
0.392 |
|
| 2020 |
Chen KL, Lai CY, Pham MT, Chein RJ, Tang Y, Lin HC. Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis. Organic Letters. PMID 32243182 DOI: 10.1021/acs.orglett.0c01132 |
0.51 |
|
| 2020 |
Hai Y, Huang A, Tang Y. Biosynthesis of Amino Acid Derived α-Pyrones by an NRPS-NRPKS Hybrid Megasynthetase in Fungi. Journal of Natural Products. PMID 32159958 DOI: 10.1021/Acs.Jnatprod.9B00989 |
0.571 |
|
| 2020 |
Yan Y, Liu N, Tang Y. Recent developments in self-resistance gene directed natural product discovery. Natural Product Reports. PMID 31912842 DOI: 10.1039/c9np00050j |
0.426 |
|
| 2019 |
Yee DA, Kakule TB, Cheng W, Chen M, Chong CTY, Hai Y, Hang LF, Hung YS, Liu N, Ohashi M, Okorafor IC, Song Y, Tang M, Zhang Z, Tang Y. Genome Mining of Alkaloidal Terpenoids from a Hybrid Terpene and Nonribosomal Peptide Biosynthetic Pathway. Journal of the American Chemical Society. PMID 31885262 DOI: 10.1021/Jacs.9B13046 |
0.625 |
|
| 2019 |
Liu L, Tang MC, Tang Y. Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes that are Precursors to Epoxycyclohexenol Natural Products. Journal of the American Chemical Society. PMID 31790246 DOI: 10.1021/jacs.9b09669 |
0.356 |
|
| 2019 |
Hai Y, Jenner M, Tang Y. Complete Stereoinversion of l-Tryptophan by a Fungal Single-Module Nonribosomal Peptide Synthetase. Journal of the American Chemical Society. PMID 31573806 DOI: 10.1021/Jacs.9B08898 |
0.564 |
|
| 2019 |
Kishimoto S, Tsunematsu Y, Matsushita T, Hara K, Hashimoto H, Tang Y, Watanabe K. Functional and Structural Analyses of trans C-Methyltransferase in Fungal Polyketide Biosynthesis. Biochemistry. PMID 31486637 DOI: 10.1021/Acs.Biochem.9B00702 |
0.553 |
|
| 2019 |
Cai Y, Hai Y, Ohashi M, Jamieson CS, Garcia-Borras M, Houk KN, Zhou J, Tang Y. Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nature Chemistry. PMID 31332284 DOI: 10.2210/Pdb6Ix9/Pdb |
0.798 |
|
| 2019 |
Yee DA, DeNicola AB, Billingsley JM, Creso JG, Subrahmanyam V, Tang Y. Engineered mitochondrial production of monoterpenes in Saccharomyces cerevisiae. Metabolic Engineering. PMID 31226348 DOI: 10.1016/j.ymben.2019.06.004 |
0.486 |
|
| 2019 |
Billingsley JM, Anguiano JL, Tang Y. Production of semi-biosynthetic nepetalactone in yeast. Journal of Industrial Microbiology & Biotechnology. PMID 31165969 DOI: 10.1007/s10295-019-02199-x |
0.505 |
|
| 2019 |
Hai Y, Huang AM, Tang Y. Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi. Proceedings of the National Academy of Sciences of the United States of America. PMID 31061132 DOI: 10.1073/Pnas.1903282116 |
0.694 |
|
| 2019 |
Tang MC, Fischer CR, Chari JV, Tan D, Suresh S, Chu A, Miranda M, Smith J, Zhang Z, Garg N, St Onge RP, Tang Y. Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi. Journal of the American Chemical Society. PMID 31051070 DOI: 10.1021/Jacs.9B01083 |
0.493 |
|
| 2019 |
Zhao Z, Ying Y, Hung YS, Tang Y. Genome Mining Reveals Neurospora crassa Can Produce the Salicylaldehyde Sordarial. Journal of Natural Products. PMID 30908040 DOI: 10.1021/acs.jnatprod.8b00983 |
0.487 |
|
| 2019 |
Zhang Z, Jamieson CS, Zhao YL, Li D, Ohashi M, Houk KN, Tang Y. Enzyme-catalyzed inverse-electron demand Diels-Alder reaction in the biosynthesis of antifungal ilicicolin H. Journal of the American Chemical Society. PMID 30905148 DOI: 10.1021/Jacs.9B02204 |
0.756 |
|
| 2019 |
Chen M, Liu Q, Gao SS, Young AE, Jacobsen SE, Tang Y. Genome mining and biosynthesis of a polyketide from a biofertilizer fungus that can facilitate reductive iron assimilation in plant. Proceedings of the National Academy of Sciences of the United States of America. PMID 30842286 DOI: 10.1073/Pnas.1819998116 |
0.484 |
|
| 2019 |
DeNicola AB, Tang Y. Therapeutic approaches to treat human spliceosomal diseases. Current Opinion in Biotechnology. 60: 72-81. PMID 30772756 DOI: 10.1016/j.copbio.2019.01.003 |
0.366 |
|
| 2019 |
Tan D, Jamieson CS, Ohashi M, Tang MC, Houk KN, Tang Y. Genome-mined Diels-Alderase catalyzes formation of the cis-octahydrodecalins of varicidin A and B. Journal of the American Chemical Society. PMID 30609896 DOI: 10.1021/Jacs.8B12010 |
0.784 |
|
| 2019 |
Tang Y, Vo T, Taiebat HA, Russell AR. Incorporating suction in to the interpretation of plate load tests on unsaturated soils Japanese Geotechnical Society Special Publication. 7: 352-359. DOI: 10.3208/JGSSP.V07.057 |
0.311 |
|
| 2018 |
Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... Tang Y, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747 |
0.461 |
|
| 2018 |
Yan Y, Liu Q, Jacobsen SE, Tang Y. The impact and prospect of natural product discovery in agriculture: New technologies to explore the diversity of secondary metabolites in plants and microorganisms for applications in agriculture. Embo Reports. PMID 30361392 DOI: 10.15252/Embr.201846824 |
0.385 |
|
| 2018 |
Jamieson CS, Ohashi M, Liu F, Tang Y, Houk KN. The expanding world of biosynthetic pericyclases: cooperation of experiment and theory for discovery. Natural Product Reports. PMID 30311924 DOI: 10.1039/C8Np00075A |
0.761 |
|
| 2018 |
Cai R, Li Y, Wang W, Gao X, Liu M, Diao Y, Tang Y, Feng Q. A novel fibrinogen variant in a Chinese pedigree with congenital dysfibrinogenemia caused by FGA P. Arg38Thr mutation: A case report. Medicine. 97: e12697. PMID 30290666 DOI: 10.1097/MD.0000000000012697 |
0.317 |
|
| 2018 |
Hu Y, Tang Y. Biotransformation and biosynthesis of natural products. Journal of Asian Natural Products Research. 1-2. PMID 30274529 DOI: 10.1080/10286020.2018.1497464 |
0.451 |
|
| 2018 |
Bond CM, Tang Y. Engineering Saccharomyces cerevisiae for production of simvastatin. Metabolic Engineering. PMID 30213650 DOI: 10.1016/j.ymben.2018.09.005 |
0.464 |
|
| 2018 |
Kishimoto S, Hara K, Hashimoto H, Hirayama Y, Champagne PA, Houk KN, Tang Y, Watanabe K. Enzymatic one-step ring contraction for quinolone biosynthesis. Nature Communications. 9: 2826. PMID 30026518 DOI: 10.1038/S41467-018-05221-5 |
0.594 |
|
| 2018 |
Yan Y, Liu Q, Zang X, Yuan S, Bat-Erdene U, Nguyen C, Gan J, Zhou J, Jacobsen SE, Tang Y. Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Nature. PMID 29995859 DOI: 10.1038/S41586-018-0319-4 |
0.491 |
|
| 2018 |
Ippoliti FM, Barber JS, Tang Y, Garg NK. Synthesis of 8-Hydroxygeraniol. The Journal of Organic Chemistry. PMID 29969566 DOI: 10.1021/Acs.Joc.8B01544 |
0.415 |
|
| 2018 |
Gao SS, Zhang T, Garcia-Borràs M, Hung YS, Billingsley JM, Houk KN, Hu Y, Tang Y. Biosynthesis of Heptacyclic Duclauxins Requires Extensive Redox Modifications of the Phenalenone Aromatic Polyketide. Journal of the American Chemical Society. PMID 29741874 DOI: 10.1021/Jacs.8B03705 |
0.445 |
|
| 2018 |
Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, ... Tang Y, et al. HEx: A heterologous expression platform for the discovery of fungal natural products. Science Advances. 4: eaar5459. PMID 29651464 DOI: 10.1126/Sciadv.Aar5459 |
0.612 |
|
| 2018 |
Walsh CT, Tu BP, Tang Y. Correction to: Eight Kinetically Stable but Thermodynamically Activated Molecules that Power Cell Metabolism. Chemical Reviews. PMID 29620360 DOI: 10.1021/Acs.Chemrev.8B00181 |
0.493 |
|
| 2018 |
Li L, Tang MC, Tang S, Gao SS, Soliman SSM, Hang L, Xu W, Ye T, Watanabe K, Tang Y. Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids. Journal of the American Chemical Society. PMID 29373009 DOI: 10.1021/Jacs.8B00056 |
0.379 |
|
| 2018 |
Hai Y, Tang Y. Biosynthesis of long-chain N-acyl amide by a truncated PKS-NRPS hybrid megasynthase in fungi. Journal of the American Chemical Society. PMID 29343058 DOI: 10.1021/Jacs.7B13350 |
0.651 |
|
| 2017 |
Walsh CT, Tu BP, Tang Y. Eight Kinetically Stable but Thermodynamically Activated Molecules that Power Cell Metabolism. Chemical Reviews. PMID 29272116 DOI: 10.1021/Acs.Chemrev.7B00510 |
0.531 |
|
| 2017 |
Walsh CT, Tang Y. Recent Advances in Enzymatic Complexity Generation: Cyclization Reactions. Biochemistry. PMID 29236467 DOI: 10.1021/Acs.Biochem.7B01161 |
0.602 |
|
| 2017 |
Walsh CT, Tang Y. Recent Advances in Enzymatic Complexity Generation: Cyclization Reactions. Biochemistry. PMID 29236467 DOI: 10.1021/Acs.Biochem.7B01161 |
0.602 |
|
| 2017 |
Billingsley JM, DeNicola AB, Barber JS, Tang MC, Horecka J, Chu A, Garg NK, Tang Y. Engineering the Biocatalytic Selectivity of Iridoid Production in Saccharomyces cerevisiae. Metabolic Engineering. PMID 28939278 DOI: 10.1016/J.Ymben.2017.09.006 |
0.515 |
|
| 2017 |
Tang MC, Cui X, He X, Ding Z, Zhu T, Tang Y, Li D. Late-Stage Terpene Cyclization by an Integral Membrane Cyclase in the Biosynthesis of Isoprenoid Epoxycyclohexenone Natural Products. Organic Letters. PMID 28926261 DOI: 10.1021/acs.orglett.7b02653 |
0.467 |
|
| 2017 |
Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN, Tang Y. SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. Nature. PMID 28902839 DOI: 10.1038/Nature23882 |
0.737 |
|
| 2017 |
Zhang Y, Zou Y, Brock NL, Huang T, Lan Y, Wang X, Deng Z, Tang Y, Lin S. Characterization of 2-Oxindole Forming Heme Enzyme MarE, Expanding the Functional Diversity of the Tryptophan Dioxygenase Superfamily. Journal of the American Chemical Society. PMID 28809552 DOI: 10.1021/Jacs.7B05517 |
0.534 |
|
| 2017 |
Hang L, Tang MC, Harvey CJB, Page CG, Li J, Hung YS, Liu N, Hillenmeyer ME, Tang Y. Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain. Angewandte Chemie (International Ed. in English). PMID 28679030 DOI: 10.1002/Anie.201705237 |
0.455 |
|
| 2017 |
Liu N, Hung YS, Gao SS, Hang L, Zou Y, Chooi YH, Tang Y. Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway. Organic Letters. PMID 28605916 DOI: 10.1021/acs.orglett.7b01534 |
0.711 |
|
| 2017 |
Sato M, Dander JE, Sato C, Hung YS, Gao SS, Tang MC, Hang L, Winter JM, Garg NK, Watanabe K, Tang Y. Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases. Journal of the American Chemical Society. PMID 28365998 DOI: 10.1021/Jacs.7B02432 |
0.629 |
|
| 2017 |
Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y. Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation. Journal of the American Chemical Society. PMID 28240554 DOI: 10.1021/Jacs.7B01089 |
0.663 |
|
| 2017 |
Zou Y, Garcia-Borràs M, Tang MC, Hirayama Y, Li DH, Li L, Watanabe K, Houk KN, Tang Y. Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. Nature Chemical Biology. PMID 28114276 DOI: 10.1038/Nchembio.2283 |
0.646 |
|
| 2017 |
Wu X, Jiao W, Li B, Li Y, Zhang Y, Wang Q, Tang Y. Decomposition of a β-O-4 lignin model compound over solid Cs-substituted polyoxometalates in anhydrous ethanol: acidity or redox property dependence? Chinese Journal of Catalysis. 38: 1216-1228. DOI: 10.1016/S1872-2067(17)62854-7 |
0.374 |
|
| 2017 |
Lin S, Guo X, Qin K, Feng L, Zhang Y, Tang Y. Efficient Production of Biomass-Derived C4Chiral Synthons in Aqueous Solution Chemcatchem. 9: 4179-4184. DOI: 10.1002/cctc.201700944 |
0.396 |
|
| 2016 |
Hang L, Liu N, Tang Y. Coordinated and Iterative Enzyme Catalysis in Fungal Polyketide Biosynthesis. Acs Catalysis. 6: 5935-5945. PMID 28529817 DOI: 10.1021/acscatal.6b01559 |
0.544 |
|
| 2016 |
Grandner JM, Cacho RA, Tang Y, Houk KN. Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin. Acs Catalysis. 6: 4506-4511. PMID 28503354 DOI: 10.1021/acscatal.6b01068 |
0.791 |
|
| 2016 |
Li L, Yu P, Tang MC, Zou Y, Gao SS, Hung YS, Zhao M, Watanabe K, Houk KN, Tang Y. Biochemical Characterization of a Eukaryotic Decalin-Forming Diels-Alderase. Journal of the American Chemical Society. 138: 15837-15840. PMID 27960349 DOI: 10.1021/Jacs.6B10452 |
0.45 |
|
| 2016 |
Tang MC, Zou Y, Watanabe K, Walsh CT, Tang Y. Oxidative Cyclization in Natural Product Biosynthesis. Chemical Reviews. PMID 27936626 DOI: 10.1021/Acs.Chemrev.6B00478 |
0.518 |
|
| 2016 |
Pfeifer BA, Tang Y. Editorial overview: Pharmaceutical biotechnology: New approaches for dynamic disease targets. Current Opinion in Biotechnology. PMID 27856096 DOI: 10.1016/J.Copbio.2016.11.002 |
0.58 |
|
| 2016 |
Zhang J, Liu N, Cacho RA, Gong Z, Liu Z, Qin W, Tang C, Tang Y, Zhou J. Structural basis of nonribosomal peptide macrocyclization in fungi. Nature Chemical Biology. PMID 27748753 DOI: 10.1038/Nchembio.2202 |
0.751 |
|
| 2016 |
Yu X, Liu F, Zou Y, Tang MC, Hang L, Houk KN, Tang Y. Biosynthesis of Strained Piperazine Alkaloids - Uncovering the Concise Pathway of Herquline A. Journal of the American Chemical Society. PMID 27690412 DOI: 10.1021/Jacs.6B09464 |
0.411 |
|
| 2016 |
Oikawa H, Tang Y. Exploring the diversification mechanism of skeletal construction in representative natural product families. The Journal of Antibiotics. 69: 471-2. PMID 27460869 DOI: 10.1038/ja.2016.69 |
0.418 |
|
| 2016 |
Ma SJ, Liang XH, Yang T, Xu JP, Tang Y, Liu YX, Chen J. [Association between development of hypertension and nutrition in school-age children in Fengdu County of Chongqing, China]. Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics. 18: 639-44. PMID 27412549 DOI: 10.7499/j.issn.1008-8830.2016.07.014 |
0.303 |
|
| 2016 |
Yamamoto T, Tsunematsu Y, Hara K, Suzuki T, Kishimoto S, Kawagishi H, Noguchi H, Hashimoto H, Tang Y, Hotta K, Watanabe K. Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 27072782 DOI: 10.1002/Anie.201600940 |
0.545 |
|
| 2016 |
Billingsley JM, DeNicola AB, Tang Y. Technology development for natural product biosynthesis in Saccharomyces cerevisiae. Current Opinion in Biotechnology. 42: 74-83. PMID 26994377 DOI: 10.1016/j.copbio.2016.02.033 |
0.483 |
|
| 2016 |
Gao SS, Duan A, Xu W, Yu P, Hang L, Houk KN, Tang Y. Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase. Journal of the American Chemical Society. PMID 26978228 DOI: 10.1021/Jacs.6B01528 |
0.331 |
|
| 2016 |
Lin HC, McMahon TC, Patel A, Corsello M, Simon A, Xu W, Zhao M, Houk KN, Garg NK, Tang Y. P450-Mediated Coupling of Indole Fragments to Forge Communesin and Unnatural Isomers. Journal of the American Chemical Society. PMID 26963294 DOI: 10.1021/Jacs.6B01413 |
0.561 |
|
| 2016 |
Sato M, Winter JM, Kishimoto S, Noguchi H, Tang Y, Watanabe K. Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis. Organic Letters. PMID 26959241 DOI: 10.1021/Acs.Orglett.6B00380 |
0.715 |
|
| 2016 |
Zhao M, Lin HC, Tang Y. Biosynthesis of the α-nitro-containing cyclic tripeptide psychrophilin. The Journal of Antibiotics. PMID 26956794 DOI: 10.1038/ja.2016.33 |
0.373 |
|
| 2016 |
Bond C, Tang Y, Li L. Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases. Fungal Genetics and Biology : Fg & B. PMID 26850128 DOI: 10.1016/j.fgb.2016.01.005 |
0.504 |
|
| 2016 |
Cacho RA, Tang Y. Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1401: 103-19. PMID 26831704 DOI: 10.1007/978-1-4939-3375-4_7 |
0.785 |
|
| 2016 |
Cochrane RV, Sanichar R, Lambkin GR, Reiz B, Xu W, Tang Y, Vederas JC. Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent. Angewandte Chemie (International Ed. in English). 55: 664-8. PMID 26783060 DOI: 10.1002/Anie.201509345 |
0.513 |
|
| 2016 |
Meng Y, Cao J, Tang Y, Lu X, Liu L. Synthesis and Anti-tumor Activity of Derivatives of Ring A of Ursolic Acid Chinese Journal of Organic Chemistry. 36: 1080. DOI: 10.6023/cjoc201510034 |
0.406 |
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| 2016 |
Zhu J, Tang Y, Tang K. Enhanced hydrogenation of ethyl-levulinate to γ-valerolactone over NiδOx stabilized Cu+ surface sites Rsc Advances. 6: 87294-87298. DOI: 10.1039/C6RA16816G |
0.344 |
|
| 2016 |
Xu W, Raetz LB, Wang P, Tang Y. An ATP-dependent ligase catalyzes the fourth ring cyclization in tetracycline biosynthesis Tetrahedron. 72: 3599-3604. DOI: 10.1016/j.tet.2015.09.029 |
0.434 |
|
| 2015 |
Wang J, Tang Y, Nan YB, Ni GQ. [A Method for Retrieving Thermospheric O/N2 from Measurements of OI 130.4 nm Dayglow]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 35: 2263-7. PMID 26672306 |
0.329 |
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| 2015 |
Tang YI, Liu Y, Zhao W, Yu T, Yu H. Caspase-8 polymorphisms and risk of oral squamous cell carcinoma. Experimental and Therapeutic Medicine. 10: 2267-2276. PMID 26668627 DOI: 10.3892/etm.2015.2832 |
0.324 |
|
| 2015 |
Noey EL, Tibrewal N, Jiménez-Osés G, Osuna S, Park J, Bond CM, Cascio D, Liang J, Zhang X, Huisman GW, Tang Y, Houk KN. Origins of stereoselectivity in evolved ketoreductases. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644568 DOI: 10.1073/Pnas.1507910112 |
0.541 |
|
| 2015 |
Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y. Understanding Programming of Fungal Iterative Polyketide Synthases: the Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase. Journal of the American Chemical Society. PMID 26630357 DOI: 10.1021/Jacs.5B11814 |
0.783 |
|
| 2015 |
Guo YY, Li H, Zhou ZX, Mao XM, Tang Y, Chen X, Jiang XH, Liu Y, Jiang H, Li YQ. Identification and Biosynthetic Characterization of Natural Aromatic Azoxy Products from Streptomyces chattanoogensis L10. Organic Letters. PMID 26623715 DOI: 10.1021/acs.orglett.5b03137 |
0.465 |
|
| 2015 |
Shi J, Wang Y, Yang W, Tang Y, Xie Z. Recent advances of pore system construction in zeolite-catalyzed chemical industry processes. Chemical Society Reviews. PMID 26567526 DOI: 10.1039/c5cs00626k |
0.376 |
|
| 2015 |
Zhang X, Tang Y, Cui L, Bai T. Continuous zoom antenna for mobile visible light communication. Applied Optics. 54: 9606-12. PMID 26560793 |
0.328 |
|
| 2015 |
Zhou J, Liu Y, Tang Y, Liu F, Zhang L, Zeng X, Feng Y, Tao Y, Yang L, Fu P. A comparison of RIFLE, AKIN, KDIGO, and Cys-C criteria for the definition of acute kidney injury in critically ill patients. International Urology and Nephrology. PMID 26560473 DOI: 10.1007/s11255-015-1150-6 |
0.354 |
|
| 2015 |
Xing Y, Tang Y, Jia J. Sex Differences in Neuropsychiatric Symptoms of Alzheimer's Disease: The Modifying Effect of Apolipoprotein E ε4 Status. Behavioural Neurology. 2015: 275256. PMID 26538817 DOI: 10.1155/2015/275256 |
0.323 |
|
| 2015 |
Cochrane RV, Gao Z, Lambkin GR, Xu W, Winter JM, Marcus SL, Tang Y, Vederas JC. Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Chembiochem : a European Journal of Chemical Biology. PMID 26493380 DOI: 10.1002/Cbic.201500428 |
0.699 |
|
| 2015 |
Wang C, Zhao Y, Zheng S, Xue J, Zhou J, Tang Y, Jiang L, Li W. Effect of enamel morphology on nanoscale adhesion forces of streptococcal bacteria : An AFM study. Scanning. 37: 313-21. PMID 26482011 DOI: 10.1002/sca.21218 |
0.342 |
|
| 2015 |
Lu H, Tang Y, Dunn PA, Wallner-Pendleton EA, Lin L, Knoll EA. Isolation and molecular characterization of newly emerging avian reovirus variants and novel strains in Pennsylvania, USA, 2011-2014. Scientific Reports. 5: 14727. PMID 26469681 DOI: 10.1038/srep14727 |
0.4 |
|
| 2015 |
Tang MC, Lin HC, Li D, Zou Y, Li J, Xu W, Cacho RA, Hillenmeyer ME, Garg NK, Tang Y. Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. Journal of the American Chemical Society. PMID 26469304 DOI: 10.1021/Jacs.5B06108 |
0.811 |
|
| 2015 |
Chen H, Dou Y, Tang Y, Zhang Z, Zheng X, Niu X, Yang J, Yu X, Diao Y. Isolation and Genomic Characterization of a Duck-Origin GPV-Related Parvovirus from Cherry Valley Ducklings in China. Plos One. 10: e0140284. PMID 26465143 DOI: 10.1371/journal.pone.0140284 |
0.399 |
|
| 2015 |
Liu N, Guo Y, Yang X, Lin H, Yang L, Shi Z, Zhong Z, Wang S, Tang Y, Gao Q. Microwave-Assisted Reactant-Protecting Strategy towards Efficient MoS2 Electrocatalysts in Hydrogen Evolution Reaction. Acs Applied Materials & Interfaces. PMID 26447801 DOI: 10.1021/acsami.5b08103 |
0.398 |
|
| 2015 |
Sato M, Yagishita F, Mino T, Uchiyama N, Patel A, Chooi YH, Goda Y, Xu W, Noguchi H, Yamamoto T, Hotta K, Houk KN, Tang Y, Watanabe K. Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition. Chembiochem : a European Journal of Chemical Biology. PMID 26360642 DOI: 10.1002/Cbic.201500386 |
0.752 |
|
| 2015 |
Mao XM, Zhan ZJ, Grayson MN, Tang MC, Xu W, Li YQ, Yin WB, Lin HC, Chooi YH, Houk KN, Tang Y. Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System. Journal of the American Chemical Society. PMID 26340065 DOI: 10.1021/Jacs.5B07816 |
0.698 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Tang Y, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.786 |
|
| 2015 |
Winter JM, Cascio D, Dietrich D, Sato M, Watanabe K, Sawaya MR, Vederas JC, Tang Y. Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. Journal of the American Chemical Society. PMID 26172141 DOI: 10.1021/Jacs.5B04520 |
0.626 |
|
| 2015 |
Mao XM, Xu W, Li D, Yin WB, Chooi YH, Li YQ, Tang Y, Hu Y. Epigenetic Genome Mining of an Endophytic Fungus Leads to the Pleiotropic Biosynthesis of Natural Products. Angewandte Chemie (International Ed. in English). 54: 7592-6. PMID 26013262 DOI: 10.1002/Anie.201502452 |
0.707 |
|
| 2015 |
Zou Y, Zhan Z, Li D, Tang M, Cacho RA, Watanabe K, Tang Y. Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids. Journal of the American Chemical Society. 137: 4980-3. PMID 25859931 DOI: 10.1021/Jacs.5B03022 |
0.814 |
|
| 2015 |
Mao XM, Luo S, Zhou RC, Wang F, Yu P, Sun N, Chen XX, Tang Y, Li YQ. Transcriptional regulation of the daptomycin gene cluster in Streptomyces roseosporus by an autoregulator, AtrA. The Journal of Biological Chemistry. 290: 7992-8001. PMID 25648897 DOI: 10.1074/jbc.M114.608273 |
0.441 |
|
| 2015 |
Lin HC, Chiou G, Chooi YH, McMahon TC, Xu W, Garg NK, Tang Y. Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids. Angewandte Chemie (International Ed. in English). 54: 3004-7. PMID 25571861 DOI: 10.1002/Anie.201411297 |
0.645 |
|
| 2015 |
Soliman S, Tang Y. Natural and engineered production of taxadiene with taxadiene synthase. Biotechnology and Bioengineering. 112: 229-35. PMID 25257933 DOI: 10.1002/Bit.25468 |
0.51 |
|
| 2015 |
Hsieh APS, Camuso G, Udrea F, Ng C, Tang Y, Vytla RK, Ranjan N, Charles A. Superjunction IGBT vs. FS IGBT for 200°C operation Proceedings of the International Symposium On Power Semiconductor Devices and Ics. 2015: 137-140. DOI: 10.1109/ISPSD.2015.7123408 |
0.302 |
|
| 2014 |
Cacho RA, Tang Y, Chooi YH. Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi. Frontiers in Microbiology. 5: 774. PMID 25642215 DOI: 10.3389/Fmicb.2014.00774 |
0.795 |
|
| 2014 |
Zou Y, Xu W, Tsunematsu Y, Tang M, Watanabe K, Tang Y. Methylation-dependent acyl transfer between polyketide synthase and nonribosomal peptide synthetase modules in fungal natural product biosynthesis. Organic Letters. 16: 6390-3. PMID 25494235 DOI: 10.1021/Ol503179V |
0.54 |
|
| 2014 |
Winter JM, Tang Y. Natural products: Getting a handle on peptides. Nature Chemistry. 6: 1037-8. PMID 25411879 DOI: 10.1038/nchem.2117 |
0.597 |
|
| 2014 |
Zhao M, Liu Y, Hsieh RS, Wang N, Tai W, Joo KI, Wang P, Gu Z, Tang Y. Clickable protein nanocapsules for targeted delivery of recombinant p53 protein. Journal of the American Chemical Society. 136: 15319-25. PMID 25289975 DOI: 10.1021/Ja508083G |
0.5 |
|
| 2014 |
Tsunematsu Y, Fukutomi M, Saruwatari T, Noguchi H, Hotta K, Tang Y, Watanabe K. Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity. Angewandte Chemie (International Ed. in English). 53: 8475-9. PMID 24939566 DOI: 10.1002/Anie.201404804 |
0.604 |
|
| 2014 |
Zabala AO, Chooi YH, Choi MS, Lin HC, Tang Y. Fungal polyketide synthase product chain-length control by partnering thiohydrolase. Acs Chemical Biology. 9: 1576-86. PMID 24845309 DOI: 10.1021/Cb500284T |
0.813 |
|
| 2014 |
Hu Y, Dietrich D, Xu W, Patel A, Thuss JA, Wang J, Yin WB, Qiao K, Houk KN, Vederas JC, Tang Y. A carbonate-forming Baeyer-Villiger monooxygenase. Nature Chemical Biology. 10: 552-4. PMID 24838010 DOI: 10.1038/Nchembio.1527 |
0.646 |
|
| 2014 |
Jiménez-Osés G, Osuna S, Gao X, Sawaya MR, Gilson L, Collier SJ, Huisman GW, Yeates TO, Tang Y, Houk KN. The role of distant mutations and allosteric regulation on LovD active site dynamics. Nature Chemical Biology. 10: 431-6. PMID 24727900 DOI: 10.1038/Nchembio.1503 |
0.635 |
|
| 2014 |
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y. Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway. Journal of the American Chemical Society. 136: 4426-36. PMID 24568283 DOI: 10.1021/Ja500881E |
0.738 |
|
| 2014 |
Mao XM, Ren NN, Sun N, Wang F, Zhou RC, Tang Y, Li YQ. Proteasome involvement in a complex cascade mediating SigT degradation during differentiation of Streptomyces coelicolor. Febs Letters. 588: 608-13. PMID 24440356 DOI: 10.1016/j.febslet.2013.12.029 |
0.454 |
|
| 2014 |
Li L, Wang P, Tang Y. C-glycosylation of anhydrotetracycline scaffold with SsfS6 from the SF2575 biosynthetic pathway. The Journal of Antibiotics. 67: 65-70. PMID 24022606 DOI: 10.1038/ja.2013.88 |
0.505 |
|
| 2014 |
Hsieh APS, Camuso G, Udrea F, Tang Y, Ng C, Ranjan N, Charles A. The effect of incomplete ionization on the turn-off behavior of FS IGBTs Ieee Electron Device Letters. 35: 105-107. DOI: 10.1109/LED.2013.2288027 |
0.313 |
|
| 2014 |
Hsieh APS, Camuso G, Udrea F, Tang Y, Ng C, Ranjan N, Charles A. Field-stop layer optimization for 1200V FS IGBT operating at 200̊C Proceedings of the International Symposium On Power Semiconductor Devices and Ics. 115-118. DOI: 10.1109/ISPSD.2014.6855989 |
0.309 |
|
| 2014 |
Wang H, Duan W, Wu Y, Tang Y, Li L. Synthesis of magnesium–aluminum layered double hydroxide intercalated with ethylene glycol by the aid of alkoxides Inorganica Chimica Acta. 418: 163-170. DOI: 10.1016/j.ica.2014.04.031 |
0.356 |
|
| 2013 |
Chooi YH, Hong YJ, Cacho RA, Tantillo DJ, Tang Y. A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis. Journal of the American Chemical Society. 135: 16805-8. PMID 24161266 DOI: 10.1021/Ja408966T |
0.821 |
|
| 2013 |
Dhingra S, Lind AL, Lin HC, Tang Y, Rokas A, Calvo AM. The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus. Plos One. 8: e77147. PMID 24116213 DOI: 10.1371/Journal.Pone.0077147 |
0.457 |
|
| 2013 |
Liu Y, Ding G, Li Y, Qu J, Ma S, Lv H, Liu Y, Wang W, Dai J, Tang Y, Yu S. Structures and absolute configurations of penicillactones A-C from an endophytic microorganism, Penicillium dangeardii Pitt. Organic Letters. 15: 5206-9. PMID 24093807 DOI: 10.1021/ol4023485 |
0.56 |
|
| 2013 |
Cacho RA, Chooi YH, Zhou H, Tang Y. Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. Acs Chemical Biology. 8: 2322-30. PMID 23978092 DOI: 10.1021/Cb400541Z |
0.83 |
|
| 2013 |
Gao X, Jiang W, Jiménez-Osés G, Choi MS, Houk KN, Tang Y, Walsh CT. An iterative, bimodular nonribosomal peptide synthetase that converts anthranilate and tryptophan into tetracyclic asperlicins. Chemistry & Biology. 20: 870-8. PMID 23890005 DOI: 10.1016/J.Chembiol.2013.04.019 |
0.631 |
|
| 2013 |
Tang H, Kong Y, Guo J, Tang Y, Xie X, Yang L, Su Q, Xie X. Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22. Cancer Letters. 340: 72-81. PMID 23851184 DOI: 10.1016/j.canlet.2013.06.027 |
0.327 |
|
| 2013 |
Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y. Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. Organic Letters. 15: 3774-7. PMID 23837609 DOI: 10.1021/Ol401723H |
0.644 |
|
| 2013 |
Yin WB, Chooi YH, Smith AR, Cacho RA, Hu Y, White TC, Tang Y. Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. Acs Synthetic Biology. 2: 629-34. PMID 23758576 DOI: 10.1021/Sb400048B |
0.799 |
|
| 2013 |
Walsh CT, Haynes SW, Ames BD, Gao X, Tang Y. Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks. Acs Chemical Biology. 8: 1366-82. PMID 23659680 DOI: 10.1021/Cb4001684 |
0.786 |
|
| 2013 |
Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y. LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis. Angewandte Chemie (International Ed. in English). 52: 6472-5. PMID 23653178 DOI: 10.1002/Anie.201302406 |
0.667 |
|
| 2013 |
Wang P, Bashiri G, Gao X, Sawaya MR, Tang Y. Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. Journal of the American Chemical Society. 135: 7138-41. PMID 23621493 DOI: 10.1021/Ja403516U |
0.446 |
|
| 2013 |
Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y. The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene. Journal of the American Chemical Society. 135: 4616-9. PMID 23488861 DOI: 10.1021/Ja312503Y |
0.622 |
|
| 2013 |
Jiang W, Cacho RA, Chiou G, Garg NK, Tang Y, Walsh CT. EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold. Journal of the American Chemical Society. 135: 4457-66. PMID 23451921 DOI: 10.1021/Ja312572V |
0.781 |
|
| 2013 |
Chooi YH, Fang J, Liu H, Filler SG, Wang P, Tang Y. Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi. Organic Letters. 15: 780-3. PMID 23368997 DOI: 10.1021/Ol303435Y |
0.707 |
|
| 2013 |
Gao Z, Wang J, Norquay AK, Qiao K, Tang Y, Vederas JC. Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates. Journal of the American Chemical Society. 135: 1735-8. PMID 23356934 DOI: 10.1021/Ja4001823 |
0.597 |
|
| 2013 |
Cacho RA, Tang Y. Bringing protein engineering and natural product biosynthesis together. Chemistry & Biology. 20: 3-5. PMID 23352133 DOI: 10.1016/j.chembiol.2013.01.005 |
0.798 |
|
| 2013 |
Haynes SW, Gao X, Tang Y, Walsh CT. Complexity generation in fungal peptidyl alkaloid biosynthesis: a two-enzyme pathway to the hexacyclic MDR export pump inhibitor ardeemin. Acs Chemical Biology. 8: 741-8. PMID 23330675 DOI: 10.1021/Cb3006787 |
0.679 |
|
| 2013 |
Xu W, Qiao K, Tang Y. Structural analysis of protein-protein interactions in type I polyketide synthases. Critical Reviews in Biochemistry and Molecular Biology. 48: 98-122. PMID 23249187 DOI: 10.3109/10409238.2012.745476 |
0.643 |
|
| 2013 |
Lin H, Chooi Y, Dhingra S, Xu W, Calvo A, Tang Y. Fumagillin Biosynthesis in Aspergillus fumigatus: a Cryptic Terpene Cyclase Gene is Involved in the Formation of β-trans-Bergamotene Planta Medica. 79. DOI: 10.1055/S-0033-1348551 |
0.651 |
|
| 2012 |
Winter JM, Sato M, Sugimoto S, Chiou G, Garg NK, Tang Y, Watanabe K. Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthase. Journal of the American Chemical Society. 134: 17900-3. PMID 23072467 DOI: 10.1021/Ja3090498 |
0.693 |
|
| 2012 |
Haynes SW, Gao X, Tang Y, Walsh CT. Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E. Journal of the American Chemical Society. 134: 17444-7. PMID 23030663 DOI: 10.1021/Ja308371Z |
0.652 |
|
| 2012 |
Wang P, Kim W, Pickens LB, Gao X, Tang Y. Heterologous expression and manipulation of three tetracycline biosynthetic pathways. Angewandte Chemie (International Ed. in English). 51: 11136-40. PMID 23024027 DOI: 10.1002/Anie.201205426 |
0.79 |
|
| 2012 |
Cacho RA, Jiang W, Chooi YH, Walsh CT, Tang Y. Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440. Journal of the American Chemical Society. 134: 16781-90. PMID 22998630 DOI: 10.1021/Ja307220Z |
0.802 |
|
| 2012 |
Chooi YH, Tang Y. Navigating the fungal polyketide chemical space: from genes to molecules. The Journal of Organic Chemistry. 77: 9933-53. PMID 22938194 DOI: 10.1021/Jo301592K |
0.72 |
|
| 2012 |
Zabala AO, Xu W, Chooi YH, Tang Y. Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation. Chemistry & Biology. 19: 1049-59. PMID 22921072 DOI: 10.1016/J.Chembiol.2012.07.004 |
0.799 |
|
| 2012 |
Gao X, Haynes SW, Ames BD, Wang P, Vien LP, Walsh CT, Tang Y. Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain. Nature Chemical Biology. 8: 823-30. PMID 22902615 DOI: 10.1038/Nchembio.1047 |
0.793 |
|
| 2012 |
Ames BD, Nguyen C, Bruegger J, Smith P, Xu W, Ma S, Wong E, Wong S, Xie X, Li JW, Vederas JC, Tang Y, Tsai SC. Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 11144-9. PMID 22733743 DOI: 10.1073/Pnas.1113029109 |
0.812 |
|
| 2012 |
Chooi YH, Wang P, Fang J, Li Y, Wu K, Wang P, Tang Y. Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases. Journal of the American Chemical Society. 134: 9428-37. PMID 22590971 DOI: 10.1021/Ja3028636 |
0.808 |
|
| 2012 |
Wang P, Gao X, Tang Y. Complexity generation during natural product biosynthesis using redox enzymes. Current Opinion in Chemical Biology. 16: 362-9. PMID 22564679 DOI: 10.1016/J.Cbpa.2012.04.008 |
0.619 |
|
| 2012 |
Biswas A, Liu Y, Liu T, Fan G, Tang Y. Polyethylene glycol-based protein nanocapsules for functional delivery of a differentiation transcription factor. Biomaterials. 33: 5459-67. PMID 22521490 DOI: 10.1016/J.Biomaterials.2012.04.012 |
0.433 |
|
| 2012 |
Zhou H, Gao Z, Qiao K, Wang J, Vederas JC, Tang Y. A fungal ketoreductase domain that displays substrate-dependent stereospecificity. Nature Chemical Biology. 8: 331-3. PMID 22406519 DOI: 10.1038/Nchembio.912 |
0.642 |
|
| 2012 |
Liu Q, Yao F, Chooi YH, Kang Q, Xu W, Li Y, Shao Y, Shi Y, Deng Z, Tang Y, You D. Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation. Chemistry & Biology. 19: 243-53. PMID 22365607 DOI: 10.1016/J.Chembiol.2011.12.018 |
0.77 |
|
| 2012 |
Winter JM, Tang Y. Synthetic biological approaches to natural product biosynthesis Current Opinion in Biotechnology. 23: 736-743. PMID 22221832 DOI: 10.1016/j.copbio.2011.12.016 |
0.676 |
|
| 2012 |
Zabala AO, Cacho RA, Tang Y. Protein engineering towards natural product synthesis and diversification. Journal of Industrial Microbiology & Biotechnology. 39: 227-41. PMID 22006344 DOI: 10.1007/S10295-011-1044-2 |
0.799 |
|
| 2012 |
Smanski MJ, Qu XD, Liu W, Shen B, Tang Y, Yu Y, Deng ZX. Biosynthesis of Pharmaceutical Natural Products and Their Pathway Engineering Organic Chemistry - Breakthroughs and Perspectives. 125-180. DOI: 10.1002/9783527664801.ch4 |
0.449 |
|
| 2011 |
Pickens LB, Tang Y, Chooi YH. Metabolic engineering for the production of natural products. Annual Review of Chemical and Biomolecular Engineering. 2: 211-36. PMID 22432617 DOI: 10.1146/Annurev-Chembioeng-061010-114209 |
0.796 |
|
| 2011 |
Qiao K, Chooi YH, Tang Y. Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1. Metabolic Engineering. 13: 723-32. PMID 21983160 DOI: 10.1016/J.Ymben.2011.09.008 |
0.763 |
|
| 2011 |
Pickens LB, Sawaya MR, Rasool H, Pashkov I, Yeates TO, Tang Y. Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. The Journal of Biological Chemistry. 286: 41539-51. PMID 21965680 DOI: 10.1074/Jbc.M111.299859 |
0.796 |
|
| 2011 |
Ames BD, Haynes SW, Gao X, Evans BS, Kelleher NL, Tang Y, Walsh CT. Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus. Biochemistry. 50: 8756-69. PMID 21899262 DOI: 10.1021/Bi201302W |
0.818 |
|
| 2011 |
Ames BD, Lee MY, Moody C, Zhang W, Tang Y, Tsai SC. Structural and biochemical characterization of ZhuI aromatase/cyclase from the R1128 polyketide pathway. Biochemistry. 50: 8392-406. PMID 21870821 DOI: 10.1021/Bi200593M |
0.795 |
|
| 2011 |
Li Y, Chooi YH, Sheng Y, Valentine JS, Tang Y. Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase. Journal of the American Chemical Society. 133: 15773-85. PMID 21866960 DOI: 10.1021/Ja206906D |
0.802 |
|
| 2011 |
Wang P, Gao X, Chooi YH, Deng Z, Tang Y. Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus. Microbiology (Reading, England). 157: 2401-9. PMID 21622525 DOI: 10.1099/Mic.0.048439-0 |
0.744 |
|
| 2011 |
Haynes SW, Ames BD, Gao X, Tang Y, Walsh CT. Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites. Biochemistry. 50: 5668-79. PMID 21591693 DOI: 10.1021/Bi2004922 |
0.797 |
|
| 2011 |
Gu Z, Biswas A, Zhao M, Tang Y. Tailoring nanocarriers for intracellular protein delivery. Chemical Society Reviews. 40: 3638-55. PMID 21566806 DOI: 10.1039/C0Cs00227E |
0.421 |
|
| 2011 |
Zhao M, Biswas A, Hu B, Joo KI, Wang P, Gu Z, Tang Y. Redox-responsive nanocapsules for intracellular protein delivery. Biomaterials. 32: 5223-30. PMID 21514660 DOI: 10.1016/J.Biomaterials.2011.03.060 |
0.534 |
|
| 2011 |
Joo KI, Fang Y, Liu Y, Xiao L, Gu Z, Tai A, Lee CL, Tang Y, Wang P. Enhanced real-time monitoring of adeno-associated virus trafficking by virus-quantum dot conjugates. Acs Nano. 5: 3523-35. PMID 21473596 DOI: 10.1021/Nn102651P |
0.482 |
|
| 2011 |
Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines. Organic Letters. 13: 1758-61. PMID 21384820 DOI: 10.1021/Ol200288W |
0.671 |
|
| 2011 |
Gao X, Chooi YH, Ames BD, Wang P, Walsh CT, Tang Y. Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicum. Journal of the American Chemical Society. 133: 2729-41. PMID 21299212 DOI: 10.1021/Ja1101085 |
0.823 |
|
| 2011 |
Biswas A, Joo KI, Liu J, Zhao M, Fan G, Wang P, Gu Z, Tang Y. Endoprotease-mediated intracellular protein delivery using nanocapsules. Acs Nano. 5: 1385-94. PMID 21268592 DOI: 10.1021/Nn1031005 |
0.535 |
|
| 2011 |
Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. Biochemistry. 50: 287-99. PMID 21069965 DOI: 10.1021/Bi1014776 |
0.574 |
|
| 2011 |
Gu Z, Biswas A, Zhao M, Tang Y. ChemInform Abstract: Tailoring Nanocarriers for Intracellular Protein Delivery Cheminform. 42: no-no. DOI: 10.1002/chin.201143277 |
0.527 |
|
| 2011 |
Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. ChemInform Abstract: A Fungal Nonribosomal Peptide Synthetase Module that Can Synthesize Thiopyrazines. Cheminform. 42: no-no. DOI: 10.1002/chin.201127180 |
0.578 |
|
| 2010 |
Zhou H, Qiao K, Gao Z, Vederas JC, Tang Y. Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogs. The Journal of Biological Chemistry. 285: 41412-21. PMID 20961859 DOI: 10.1074/Jbc.M110.183574 |
0.652 |
|
| 2010 |
Gao X, Wang P, Tang Y. Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. Applied Microbiology and Biotechnology. 88: 1233-42. PMID 20853106 DOI: 10.1007/S00253-010-2860-4 |
0.578 |
|
| 2010 |
Xu W, Cai X, Jung ME, Tang Y. Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiae. Journal of the American Chemical Society. 132: 13604-7. PMID 20828130 DOI: 10.1021/Ja107084D |
0.523 |
|
| 2010 |
Chooi YH, Tang Y. Adding the lipo to lipopeptides: do more with less. Chemistry & Biology. 17: 791-3. PMID 20797606 DOI: 10.1016/j.chembiol.2010.08.001 |
0.637 |
|
| 2010 |
Gu Z, Biswas A, Joo KI, Hu B, Wang P, Tang Y. Probing protease activity by single-fluorescent-protein nanocapsules. Chemical Communications (Cambridge, England). 46: 6467-9. PMID 20657917 DOI: 10.1039/C0Cc01439G |
0.522 |
|
| 2010 |
Chooi YH, Cacho R, Tang Y. Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum. Chemistry & Biology. 17: 483-94. PMID 20534346 DOI: 10.1016/J.Chembiol.2010.03.015 |
0.803 |
|
| 2010 |
Pickens LB, Tang Y. Oxytetracycline biosynthesis. The Journal of Biological Chemistry. 285: 27509-15. PMID 20522541 DOI: 10.1074/jbc.R110.130419 |
0.805 |
|
| 2010 |
Li Y, Image II, Xu W, Image I, Tang Y, Image I. Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. The Journal of Biological Chemistry. 285: 22764-73. PMID 20479000 DOI: 10.1074/Jbc.M110.128504 |
0.656 |
|
| 2010 |
Zhou H, Li Y, Tang Y. Cyclization of aromatic polyketides from bacteria and fungi. Natural Product Reports. 27: 839-68. PMID 20358042 DOI: 10.1039/B911518H |
0.585 |
|
| 2010 |
Zhou H, Qiao K, Gao Z, Meehan MJ, Li JW, Zhao X, Dorrestein PC, Vederas JC, Tang Y. Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis. Journal of the American Chemical Society. 132: 4530-1. PMID 20222707 DOI: 10.1021/Ja100060K |
0.671 |
|
| 2010 |
Yan M, Du J, Gu Z, Liang M, Hu Y, Zhang W, Priceman S, Wu L, Zhou ZH, Liu Z, Segura T, Tang Y, Lu Y. A novel intracellular protein delivery platform based on single-protein nanocapsules. Nature Nanotechnology. 5: 48-53. PMID 19935648 DOI: 10.1038/Nnano.2009.341 |
0.3 |
|
| 2010 |
Zhou H, Li Y, Tang Y. ChemInform Abstract: Cyclization of Aromatic Polyketides from Bacteria and Fungi Cheminform. 41: no-no. DOI: 10.1002/chin.201037270 |
0.653 |
|
| 2010 |
Chi C, Wang B, Shan W, Zhang Y, Tang Y. ChemInform Abstract: Characterization of Vesicular Mesostructured Silica Synthesized under Alkaline Conditions Cheminform. 41. DOI: 10.1002/chin.201019204 |
0.367 |
|
| 2009 |
Gu Z, Yan M, Hu B, Joo KI, Biswas A, Huang Y, Lu Y, Wang P, Tang Y. Protein nanocapsule weaved with enzymatically degradable polymeric network. Nano Letters. 9: 4533-8. PMID 19995089 DOI: 10.1021/Nl902935B |
0.542 |
|
| 2009 |
Pickens LB, Kim W, Wang P, Zhou H, Watanabe K, Gomi S, Tang Y. Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575. Journal of the American Chemical Society. 131: 17677-89. PMID 19908837 DOI: 10.1021/Ja907852C |
0.814 |
|
| 2009 |
Ma SM, Li JW, Choi JW, Zhou H, Lee KK, Moorthie VA, Xie X, Kealey JT, Da Silva NA, Vederas JC, Tang Y. Complete reconstitution of a highly reducing iterative polyketide synthase. Science (New York, N.Y.). 326: 589-92. PMID 19900898 DOI: 10.1126/Science.1175602 |
0.635 |
|
| 2009 |
Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017 |
0.796 |
|
| 2009 |
Tang Y, Wang P, Van Deventer JA, Link AJ, Tirrell DA. Introduction of an aliphatic ketone into recombinant proteins in a bacterial strain that overexpresses an editing-impaired leucyl-tRNA synthetase. Chembiochem : a European Journal of Chemical Biology. 10: 2188-90. PMID 19670197 DOI: 10.1002/Cbic.200900407 |
0.785 |
|
| 2009 |
Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Acyltransferase mediated polyketide release from a fungal megasynthase. Journal of the American Chemical Society. 131: 8388-9. PMID 19530726 DOI: 10.1021/Ja903203G |
0.487 |
|
| 2009 |
Wang M, Zhou H, Wirz M, Tang Y, Boddy CN. A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading. Biochemistry. 48: 6288-90. PMID 19530704 DOI: 10.1021/Bi9009049 |
0.696 |
|
| 2009 |
Wang P, Zhang W, Zhan J, Tang Y. Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1544-50. PMID 19472250 DOI: 10.1002/Cbic.200900122 |
0.585 |
|
| 2009 |
Zhan J, Qiao K, Tang Y. Investigation of tailoring modifications in pradimicin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1447-52. PMID 19431159 DOI: 10.1002/Cbic.200900082 |
0.602 |
|
| 2009 |
Zhang W, Tang Y. In vitro analysis of type II polyketide synthase. Methods in Enzymology. 459: 367-93. PMID 19362648 DOI: 10.1016/S0076-6879(09)04616-3 |
0.356 |
|
| 2009 |
Pickens LB, Tang Y. Decoding and engineering tetracycline biosynthesis. Metabolic Engineering. 11: 69-75. PMID 19007902 DOI: 10.1016/J.Ymben.2008.10.001 |
0.782 |
|
| 2009 |
Xie X, Pashkov I, Gao X, Guerrero JL, Yeates TO, Tang Y. Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity. Biotechnology and Bioengineering. 102: 20-8. PMID 18988191 DOI: 10.1002/Bit.22028 |
0.652 |
|
| 2009 |
Cheng Z, Tang Y, Chen Y, Kim S, Liu H, Li SS, Gu W, Zhao Y. Molecular characterization of propionyllysines in non-histone proteins. Molecular & Cellular Proteomics : McP. 8: 45-52. PMID 18753126 DOI: 10.1074/Mcp.M800224-Mcp200 |
0.426 |
|
| 2008 |
Zhang W, Li Y, Tang Y. Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 105: 20683-8. PMID 19075227 DOI: 10.1073/Pnas.0809084105 |
0.724 |
|
| 2008 |
Zhou H, Xie X, Tang Y. Engineering natural products using combinatorial biosynthesis and biocatalysis. Current Opinion in Biotechnology. 19: 590-6. PMID 18992814 DOI: 10.1016/J.Copbio.2008.10.012 |
0.639 |
|
| 2008 |
Zhan J, Watanabe K, Tang Y. Synergistic actions of a monooxygenase and cyclases in aromatic polyketide biosynthesis. Chembiochem : a European Journal of Chemical Biology. 9: 1710-5. PMID 18604835 DOI: 10.1002/Cbic.200800178 |
0.489 |
|
| 2008 |
Zhou H, Zhan J, Watanabe K, Xie X, Tang Y. A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae. Proceedings of the National Academy of Sciences of the United States of America. 105: 6249-54. PMID 18427109 DOI: 10.1073/Pnas.0800657105 |
0.655 |
|
| 2008 |
Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J. Identifying the minimal enzymes required for anhydrotetracycline biosynthesis. Journal of the American Chemical Society. 130: 6068-9. PMID 18422316 DOI: 10.1021/Ja800951E |
0.641 |
|
| 2008 |
Zhang W, Tang Y. Combinatorial biosynthesis of natural products. Journal of Medicinal Chemistry. 51: 2629-33. PMID 18393406 DOI: 10.1021/Jm701269V |
0.364 |
|
| 2008 |
Ames BD, Korman TP, Zhang W, Smith P, Vu T, Tang Y, Tsai SC. Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. Proceedings of the National Academy of Sciences of the United States of America. 105: 5349-54. PMID 18388203 DOI: 10.1073/Pnas.0709223105 |
0.793 |
|
| 2008 |
Ma SM, Zhan J, Xie X, Watanabe K, Tang Y, Zhang W. Redirecting the cyclization steps of fungal polyketide synthase. Journal of the American Chemical Society. 130: 38-9. PMID 18072779 DOI: 10.1021/Ja078091O |
0.716 |
|
| 2008 |
Zhang W, Tang Y. ChemInform Abstract: Combinatorial Biosynthesis of Natural Products Cheminform. 39. DOI: 10.1002/chin.200830264 |
0.447 |
|
| 2007 |
Ma SM, Zhan J, Watanabe K, Xie X, Zhang W, Wang CC, Tang Y. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. Journal of the American Chemical Society. 129: 10642-3. PMID 17696354 DOI: 10.1021/Ja074865P |
0.729 |
|
| 2007 |
Zhang W, Watanabe K, Wang CC, Tang Y. Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway. The Journal of Biological Chemistry. 282: 25717-25. PMID 17631493 DOI: 10.1074/Jbc.M703437200 |
0.695 |
|
| 2007 |
Xie X, Wong WW, Tang Y. Improving simvastatin bioconversion in Escherichia coli by deletion of bioH. Metabolic Engineering. 9: 379-86. PMID 17625941 DOI: 10.1016/J.Ymben.2007.05.006 |
0.593 |
|
| 2007 |
Zhang W, Wilke BI, Zhan J, Watanabe K, Boddy CN, Tang Y. A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis. Journal of the American Chemical Society. 129: 9304-5. PMID 17625867 DOI: 10.1021/Ja0736919 |
0.765 |
|
| 2007 |
Ma SM, Tang Y. Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB. The Febs Journal. 274: 2854-64. PMID 17466016 DOI: 10.1111/j.1742-4658.2007.05818.x |
0.459 |
|
| 2007 |
Xie X, Tang Y. Efficient synthesis of simvastatin by use of whole-cell biocatalysis. Applied and Environmental Microbiology. 73: 2054-60. PMID 17277201 DOI: 10.1128/AEM.02820-06 |
0.568 |
|
| 2007 |
Chen Y, Sprung R, Tang Y, Ball H, Sangras B, Kim SC, Falck JR, Peng J, Gu W, Zhao Y. Lysine propionylation and butyrylation are novel post-translational modifications in histones. Molecular & Cellular Proteomics : McP. 6: 812-9. PMID 17267393 DOI: 10.1074/Mcp.M700021-Mcp200 |
0.425 |
|
| 2007 |
Wang L, Shen J, Tang Y, Chen Y, Wang W, Cai Z, Du Z. Synthetic Improvements in the Preparation of Clopidogrel Organic Process Research & Development. 11: 487-489. DOI: 10.1021/op700025d |
0.374 |
|
| 2006 |
Zhang W, Watanabe K, Wang CC, Tang Y. Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase. Journal of Natural Products. 69: 1633-6. PMID 17125237 DOI: 10.1021/Np060290I |
0.672 |
|
| 2006 |
Tang Y, Lee HY, Tang Y, Kim CY, Mathews I, Khosla C. Structural and functional studies on SCO1815: a beta-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2). Biochemistry. 45: 14085-93. PMID 17115703 DOI: 10.1021/Bi061187V |
0.627 |
|
| 2006 |
Xie X, Watanabe K, Wojcicki WA, Wang CC, Tang Y. Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. Chemistry & Biology. 13: 1161-9. PMID 17113998 DOI: 10.1016/J.Chembiol.2006.09.008 |
0.711 |
|
| 2006 |
Zhang W, Ames BD, Tsai SC, Tang Y. Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. Applied and Environmental Microbiology. 72: 2573-80. PMID 16597959 DOI: 10.1128/Aem.72.4.2573-2580.2006 |
0.781 |
|
| 2005 |
Lee TS, Khosla C, Tang Y. Orthogonal protein interactions in spore pigment producing and antibiotic producing polyketide synthases. The Journal of Antibiotics. 58: 663-6. PMID 16392683 DOI: 10.1038/Ja.2005.91 |
0.663 |
|
| 2005 |
Lee TS, Khosla C, Tang Y. Engineered biosynthesis of aklanonic acid analogues. Journal of the American Chemical Society. 127: 12254-62. PMID 16131203 DOI: 10.1021/Ja051429Z |
0.685 |
|
| 2005 |
Tang Y. Gene therapy for myocardial ischemia using the hypoxia-inducible double plasmid system Methods in Molecular Medicine. 112: 37-47. PMID 16010009 DOI: 10.1385/1-59259-879-X:037 |
0.367 |
|
| 2005 |
Khosla C, Tang Y. Chemistry. A new route to designer antibiotics. Science (New York, N.Y.). 308: 367-8. PMID 15831747 DOI: 10.1126/Science.1111415 |
0.554 |
|
| 2005 |
WangAuthors contributed equally to D, Zhu G, Zhang Y, Yang W, Wu B, Tang Y, Xie Z. Controlled release and conversion of guest species in zeolite microcapsules New Journal of Chemistry. 29: 272. DOI: 10.1039/B414127J |
0.326 |
|
| 2004 |
Kumar P, Khosla C, Tang Y. Manipulation and analysis of polyketide synthases. Methods in Enzymology. 388: 269-93. PMID 15289078 DOI: 10.1016/S0076-6879(04)88023-6 |
0.653 |
|
| 2004 |
Tang Y, Koppisch AT, Khosla C. The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an acyl-ACP thioesterase that edits acetyl primer units. Biochemistry. 43: 9546-55. PMID 15260498 DOI: 10.1021/Bi049157K |
0.601 |
|
| 2004 |
Tang Y, Lee TS, Khosla C. Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases. Plos Biology. 2: E31. PMID 14966533 DOI: 10.1371/Journal.Pbio.0020031 |
0.695 |
|
| 2004 |
Tang Y, Lee TS, Lee HY, Khosla C. Exploring the biosynthetic potential of bimodular aromatic polyketide synthases Tetrahedron. 60: 7659-7671. DOI: 10.1016/J.Tet.2004.05.118 |
0.691 |
|
| 2003 |
Tang Y, Tsai SC, Khosla C. Polyketide chain length control by chain length factor. Journal of the American Chemical Society. 125: 12708-9. PMID 14558809 DOI: 10.1021/Ja0378759 |
0.58 |
|
| 2003 |
Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R. Novel factor XIII probes for blood coagulation imaging. Chembiochem : a European Journal of Chemical Biology. 4: 897-9. PMID 12964167 DOI: 10.1002/Cbic.200300602 |
0.316 |
|
| 2003 |
Cirino PC, Tang Y, Takahashi K, Tirrell DA, Arnold FH. Global incorporation of norleucine in place of methionine in cytochrome P450 BM-3 heme domain increases peroxygenase activity. Biotechnology and Bioengineering. 83: 729-34. PMID 12889037 DOI: 10.1002/Bit.10718 |
0.624 |
|
| 2003 |
Wang P, Tang Y, Tirrell DA. Incorporation of trifluoroisoleucine into proteins in vivo. Journal of the American Chemical Society. 125: 6900-6. PMID 12783542 DOI: 10.1021/Ja0298287 |
0.655 |
|
| 2003 |
Li W, Jiang X, Ma H, Yu TS, Ma L, Puente JG, Tang Y, He X, Ma S, Jin S, Kong L, Chen C, Liu L. Awareness, treatment and control of hypertension in patients attending hospital clinics in China. Journal of Hypertension. 21: 1191-7. PMID 12777957 DOI: 10.1097/01.hjh.0000059022.82022.31 |
0.316 |
|
| 2003 |
Tang Y, Lee TS, Kobayashi S, Khosla C. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity. Biochemistry. 42: 6588-95. PMID 12767243 DOI: 10.1021/Bi0341962 |
0.692 |
|
| 2002 |
Tang Y, Tirrell DA. Attenuation of the editing activity of the Escherichia coli leucyl-tRNA synthetase allows incorporation of novel amino acids into proteins in vivo. Biochemistry. 41: 10635-45. PMID 12186549 DOI: 10.1021/Bi026130X |
0.587 |
|
| 2001 |
Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 29712367 DOI: 10.1002/1521-3773(20010417)40:8<1494::Aid-Anie1494>3.0.Co;2-X |
0.442 |
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| 2001 |
Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability This work was supported by a grant from the U.S. Army Research Office. Y. Tang is supported by a Whitaker Graduate Research Fellowship. We thank Dr. Gary Hathaway for performing matrix-assisted laser desorption/ionization analyses. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 11317312 DOI: 10.1002/1521-3773(20010417)40:8<1494::AID-ANIE1494>3.0.CO;2-X |
0.524 |
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| 1997 |
XU J, TANG Y, ZHANG H, GAO Z. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 27: 303-317. DOI: 10.1023/A:1007962502627 |
0.389 |
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| 1988 |
Tang Y, Tian S, Wu S, Hua J, Wu G, Zhao E, Lu Y, Zhu Y, Tsou K. Isolation and structure of ranamargarin, a new tachykinin from the skin of the chinese frog rana margaratae Regulatory Peptides. 22: 182. DOI: 10.1016/0167-0115(88)90402-8 |
0.359 |
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