Mariann Bienz, PhD - Publications

Affiliations: 
MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
Area:
Wnt signalling
Website:
http://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/m-bienz

85/175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang H, Bienz M, Yan XX, Xu W. Structural basis of the interaction between BCL9-Pygo and LDB-SSBP complexes in assembling the Wnt enhanceosome. Nature Communications. 14: 3702. PMID 37349336 DOI: 10.1038/s41467-023-39439-9  0.411
2022 Mieszczanek J, Strutt H, Rutherford TJ, Strutt D, Bienz M, Gammons MV. Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling. Journal of Cell Science. PMID 35542970 DOI: 10.1242/jcs.259547  0.335
2021 Beitia GJ, Rutherford TJ, Freund SMV, Pelham HR, Bienz M, Gammons MV. Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34155117 DOI: 10.1073/pnas.2103258118  0.363
2020 Gammons MV, Renko M, Flack JE, Mieszczanek J, Bienz M. Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin. Elife. 9. PMID 33025907 DOI: 10.7554/eLife.59879  0.304
2020 Kan W, Enos MD, Korkmazhan E, Muennich S, Chen DH, Gammons MV, Vasishtha M, Bienz M, Dunn AR, Skiniotis G, Weis WI. Limited Dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction. Elife. 9. PMID 32297861 DOI: 10.7554/Elife.55015  0.517
2019 Yamanishi K, Fiedler M, Terawaki SI, Higuchi Y, Bienz M, Shibata N. A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to β-catenin. Science Signaling. 12. PMID 31822591 DOI: 10.1126/scisignal.aaw5505  0.418
2019 Renko M, Fiedler M, Rutherford TJ, Schaefer JV, Plückthun A, Bienz M. Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570581 DOI: 10.1073/Pnas.1912705116  0.312
2019 Mieszczanek J, van Tienen LM, Ibrahim AEK, Winton DJ, Bienz M. Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models. Nature Communications. 10: 724. PMID 30760710 DOI: 10.1038/S41467-018-08164-Z  0.731
2017 Gammons M, Bienz M. Multiprotein complexes governing Wnt signal transduction. Current Opinion in Cell Biology. 51: 42-49. PMID 29153704 DOI: 10.1016/J.Ceb.2017.10.008  0.521
2017 Flack JE, Mieszczanek J, Novcic N, Bienz M. Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5. Molecular Cell. PMID 28689657 DOI: 10.1016/J.Molcel.2017.06.009  0.562
2017 van Tienen LM, Mieszczanek J, Fiedler M, Rutherford T, Bienz M. Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9. Elife. 6. PMID 28358670 DOI: 10.7554/eLife.27150  0.71
2017 van Tienen LM, Mieszczanek J, Fiedler M, Rutherford TJ, Bienz M. Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9. Elife. 6. PMID 28296634 DOI: 10.7554/Elife.20882  0.741
2016 Gammons MV, Rutherford TJ, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. Journal of Cell Science. 129: 3892-3902. PMID 27744318 DOI: 10.1242/Jcs.195685  0.528
2016 Gammons MV, Renko M, Johnson CM, Rutherford TJ, Bienz M. Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled. Molecular Cell. PMID 27692984 DOI: 10.1016/J.Molcel.2016.08.026  0.493
2016 Teo AED, Garg S, Haris Shaikh L, Zhou J, Karet Frankl FE, Gurnell M, Happerfield L, Marker A, Bienz M, Azizan EAB, Brown MJ. Effect of somatic CTNNB1 mutations on adrenocortical cell de-differentiation in adenoma presenting in early pregnancy or menopause Annales D'Endocrinologie. 77: 161-162. DOI: 10.1016/J.Ando.2016.04.022  0.374
2015 Mund T, Graeb M, Mieszczanek J, Gammons M, Pelham HR, Bienz M. Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled. Open Biology. 5. PMID 26701932 DOI: 10.1098/Rsob.150185  0.518
2015 Teo AE, Garg S, Haris Shaikh L, Zhou J, Karet Frankl FE, Gurnell M, Happerfield L, Marker A, Bienz M, Azizan EA, Brown MJ. Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations. The New England Journal of Medicine. PMID 26397949 DOI: 10.1056/Nejmoa1504869  0.329
2015 Fiedler M, Graeb M, Mieszczanek J, Rutherford TJ, Johnson CM, Bienz M. An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Elife. 4. PMID 26312500 DOI: 10.7554/Elife.09073  0.531
2015 Madrzak J, Fiedler M, Johnson CM, Ewan R, Knebel A, Bienz M, Chin JW. Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization. Nature Communications. 6: 6718. PMID 25907794 DOI: 10.1038/Ncomms7718  0.387
2014 Silva AL, Dawson SN, Arends MJ, Guttula K, Hall N, Cameron EA, Huang TH, Brenton JD, Tavaré S, Bienz M, Ibrahim AE. Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists. Bmc Cancer. 14: 891. PMID 25432628 DOI: 10.1186/1471-2407-14-891  0.413
2014 Miller TC, Rutherford TJ, Birchall K, Chugh J, Fiedler M, Bienz M. Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger. Acs Chemical Biology. 9: 2864-74. PMID 25323450 DOI: 10.1021/Cb500585S  0.397
2014 Bienz M. Signalosome assembly by domains undergoing dynamic head-to-tail polymerization. Trends in Biochemical Sciences. 39: 487-95. PMID 25239056 DOI: 10.1016/J.Tibs.2014.08.006  0.373
2014 de la Roche M, Ibrahim AE, Mieszczanek J, Bienz M. LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors. Cancer Research. 74: 1495-505. PMID 24419084 DOI: 10.1158/0008-5472.Can-13-2682  0.48
2013 Miller TC, Mieszczanek J, Sánchez-Barrena MJ, Rutherford TJ, Fiedler M, Bienz M. Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2. Structure (London, England : 1993). 21: 2208-20. PMID 24183574 DOI: 10.1016/J.Str.2013.09.013  0.446
2012 Bienz M, He X. Biochemistry. A lipid linchpin for Wnt-Fz docking. Science (New York, N.Y.). 337: 44-5. PMID 22653728 DOI: 10.1126/Science.1224468  0.41
2012 de la Roche M, Rutherford TJ, Gupta D, Veprintsev DB, Saxty B, Freund SM, Bienz M. An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid. Nature Communications. 3: 680. PMID 22353711 DOI: 10.1038/Ncomms1680  0.471
2012 Licchesi JD, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M, Komander D. An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains. Nature Structural & Molecular Biology. 19: 62-71. PMID 22157957 DOI: 10.1038/Nsmb.2169  0.32
2011 Mendoza-Topaz C, Mieszczanek J, Bienz M. The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled. Open Biology. 1: 110013. PMID 22645652 DOI: 10.1098/Rsob.110013  0.491
2011 Metcalfe C, Bienz M. Inhibition of GSK3 by Wnt signalling--two contrasting models. Journal of Cell Science. 124: 3537-44. PMID 22083140 DOI: 10.1242/Jcs.091991  0.49
2011 Fiedler M, Mendoza-Topaz C, Rutherford TJ, Mieszczanek J, Bienz M. Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin. Proceedings of the National Academy of Sciences of the United States of America. 108: 1937-42. PMID 21245303 DOI: 10.1073/Pnas.1017063108  0.534
2010 Metcalfe C, Ibrahim AE, Graeb M, de la Roche M, Schwarz-Romond T, Fiedler M, Winton DJ, Corfield A, Bienz M. Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. Cancer Research. 70: 6629-38. PMID 20663899 DOI: 10.1158/0008-5472.Can-10-1616  0.468
2010 Miller TC, Rutherford TJ, Johnson CM, Fiedler M, Bienz M. Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor. Journal of Molecular Biology. 401: 969-84. PMID 20637214 DOI: 10.1016/J.Jmb.2010.07.007  0.329
2010 Metcalfe C, Mendoza-Topaz C, Mieszczanek J, Bienz M. Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization. Journal of Cell Science. 123: 1588-99. PMID 20388731 DOI: 10.1242/Jcs.067546  0.423
2008 Mieszczanek J, de la Roche M, Bienz M. A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America. 105: 19324-9. PMID 19036929 DOI: 10.1073/Pnas.0806098105  0.529
2008 de la Roche M, Worm J, Bienz M. The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells. Bmc Cancer. 8: 199. PMID 18627596 DOI: 10.1186/1471-2407-8-199  0.362
2008 Fiedler M, Sánchez-Barrena MJ, Nekrasov M, Mieszczanek J, Rybin V, Müller J, Evans P, Bienz M. Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Molecular Cell. 30: 507-18. PMID 18498752 DOI: 10.1016/J.Molcel.2008.03.011  0.433
2008 Tran H, Hamada F, Schwarz-Romond T, Bienz M. Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes & Development. 22: 528-42. PMID 18281465 DOI: 10.1101/Gad.463208  0.483
2007 Schwarz-Romond T, Metcalfe C, Bienz M. Dynamic recruitment of axin by Dishevelled protein assemblies. Journal of Cell Science. 120: 2402-12. PMID 17606995 DOI: 10.1242/Jcs.002956  0.443
2007 Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M, Niehrs C. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science (New York, N.Y.). 316: 1619-22. PMID 17569865 DOI: 10.1126/Science.1137065  0.478
2007 Schwarz-Romond T, Fiedler M, Shibata N, Butler PJ, Kikuchi A, Higuchi Y, Bienz M. The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization. Nature Structural & Molecular Biology. 14: 484-92. PMID 17529994 DOI: 10.1038/Nsmb1247  0.447
2007 de la Roche M, Bienz M. Wingless-independent association of Pygopus with dTCF target genes. Current Biology : Cb. 17: 556-61. PMID 17320388 DOI: 10.1016/J.Cub.2007.01.063  0.515
2006 Bienz M. The PHD finger, a nuclear protein-interaction domain. Trends in Biochemical Sciences. 31: 35-40. PMID 16297627 DOI: 10.1016/J.Tibs.2005.11.001  0.328
2005 Schwarz-Romond T, Merrifield C, Nichols BJ, Bienz M. The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles. Journal of Cell Science. 118: 5269-77. PMID 16263762 DOI: 10.1242/Jcs.02646  0.396
2005 Hanson KK, Kelley AC, Bienz M. Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development. Development (Cambridge, England). 132: 4777-87. PMID 16224046 DOI: 10.1242/Dev.02057  0.375
2005 Bray S, Musisi H, Bienz M. Bre1 is required for Notch signaling and histone modification. Developmental Cell. 8: 279-86. PMID 15691768 DOI: 10.1016/J.Devcel.2004.11.020  0.429
2005 Bienz M. beta-Catenin: a pivot between cell adhesion and Wnt signalling. Current Biology : Cb. 15: R64-7. PMID 15668160 DOI: 10.1016/j.cub.2004.12.058  0.335
2004 Hamada F, Bienz M. The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF. Developmental Cell. 7: 677-85. PMID 15525529 DOI: 10.1016/j.devcel.2004.08.022  0.302
2004 Cliffe A, Mieszczanek J, Bienz M. Intracellular shuttling of a Drosophila APC tumour suppressor homolog. Bmc Cell Biology. 5: 37. PMID 15458577 DOI: 10.1186/1471-2121-5-37  0.352
2004 Bienz M, Hamada F. Adenomatous polyposis coli proteins and cell adhesion. Current Opinion in Cell Biology. 16: 528-35. PMID 15363803 DOI: 10.1016/J.Ceb.2004.08.001  0.463
2004 Townsley FM, Cliffe A, Bienz M. Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function. Nature Cell Biology. 6: 626-33. PMID 15208637 DOI: 10.1038/ncb1141  0.374
2004 Townsley FM, Thompson B, Bienz M. Pygopus residues required for its binding to Legless are critical for transcription and development. The Journal of Biological Chemistry. 279: 5177-83. PMID 14612447 DOI: 10.1074/Jbc.M309722200  0.663
2003 Cliffe A, Hamada F, Bienz M. A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling. Current Biology : Cb. 13: 960-6. PMID 12781135 DOI: 10.1016/S0960-9822(03)00370-1  0.477
2003 Bienz M, Clevers H. Armadillo/beta-catenin signals in the nucleus--proof beyond a reasonable doubt? Nature Cell Biology. 5: 179-82. PMID 12646868 DOI: 10.1038/Ncb0303-179  0.363
2003 Rosin-Arbesfeld R, Cliffe A, Brabletz T, Bienz M. Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. The Embo Journal. 22: 1101-13. PMID 12606575 DOI: 10.1093/emboj/cdg105  0.342
2002 Saller E, Kelley A, Bienz M. The transcriptional repressor Brinker antagonizes Wingless signaling. Genes & Development. 16: 1828-38. PMID 12130542 DOI: 10.1101/gad.230002  0.342
2002 Bienz M. The subcellular destinations of APC proteins. Nature Reviews. Molecular Cell Biology. 3: 328-38. PMID 11988767 DOI: 10.1038/Nrm806  0.438
2002 Thompson B, Townsley F, Rosin-Arbesfeld R, Musisi H, Bienz M. A new nuclear component of the Wnt signalling pathway. Nature Cell Biology. 4: 367-73. PMID 11988739 DOI: 10.1038/Ncb786  0.694
2002 Hamada F, Bienz M. A Drosophila APC tumour suppressor homologue functions in cellular adhesion. Nature Cell Biology. 4: 208-13. PMID 11862214 DOI: 10.1038/Ncb755  0.393
2001 Rosin-Arbesfeld R, Ihrke G, Bienz M. Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells. The Embo Journal. 20: 5929-39. PMID 11689433 DOI: 10.1093/Emboj/20.21.5929  0.313
2001 Barker N, Hurlstone A, Musisi H, Miles A, Bienz M, Clevers H. The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. The Embo Journal. 20: 4935-43. PMID 11532957 DOI: 10.1093/Emboj/20.17.4935  0.357
2001 Saller E, Bienz M. Direct competition between Brinker and Drosophila Mad in Dpp target gene transcription. Embo Reports. 2: 298-305. PMID 11306550 DOI: 10.1093/embo-reports/kve068  0.341
2001 Freeman M, Bienz M. EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye. Embo Reports. 2: 157-62. PMID 11258709 DOI: 10.1093/Embo-Reports/Kve019  0.41
2001 Bienz M. Spindles cotton on to junctions, APC and EB1. Nature Cell Biology. 3: E67-8. PMID 11231588 DOI: 10.1038/35060140  0.334
2001 Waltzer L, Vandel L, Bienz M. Teashirt is required for transcriptional repression mediated by high Wingless levels. The Embo Journal. 20: 137-45. PMID 11226164 DOI: 10.1093/emboj/20.1.137  0.306
2000 Townsley FM, Bienz M. Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo. Current Biology : Cb. 10: 1339-48. PMID 11084333 DOI: 10.1016/S0960-9822(00)00770-3  0.438
2000 Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell. 103: 311-20. PMID 11057903 DOI: 10.1016/S0092-8674(00)00122-7  0.358
2000 Szüts D, Bienz M. An autoregulatory function of Dfos during Drosophila endoderm induction. Mechanisms of Development. 98: 71-6. PMID 11044608 DOI: 10.1016/S0925-4773(00)00455-X  0.676
2000 Rosin-Arbesfeld R, Townsley F, Bienz M. The APC tumour suppressor has a nuclear export function. Nature. 406: 1009-12. PMID 10984057 DOI: 10.1038/35023016  0.479
2000 Szüts D, Bienz M. LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator. Proceedings of the National Academy of Sciences of the United States of America. 97: 5351-6. PMID 10805795 DOI: 10.1073/Pnas.97.10.5351  0.686
1999 Waltzer L, Bienz M. The control of beta-catenin and TCF during embryonic development and cancer. Cancer Metastasis Reviews. 18: 231-46. PMID 10728986 DOI: 10.1023/A:1006321324190  0.443
1999 Yu X, Waltzer L, Bienz M. A new Drosophila APC homologue associated with adhesive zones of epithelial cells. Nature Cell Biology. 1: 144-51. PMID 10559900 DOI: 10.1038/11064  0.421
1999 Bienz M. APC: the plot thickens. Current Opinion in Genetics & Development. 9: 595-603. PMID 10508699 DOI: 10.1016/S0959-437X(99)00016-7  0.423
1999 Yu X, Bienz M. Ubiquitous expression of a Drosophila adenomatous polyposis coli homolog and its localization in cortical actin caps. Mechanisms of Development. 84: 69-73. PMID 10473121 DOI: 10.1016/S0925-4773(99)00072-6  0.302
1999 Waltzer L, Bienz M. A function of CBP as a transcriptional co-activator during Dpp signalling. The Embo Journal. 18: 1630-41. PMID 10075933 DOI: 10.1093/emboj/18.6.1630  0.384
1998 Yu X, Riese J, Eresh S, Bienz M. Transcriptional repression due to high levels of Wingless signalling. The Embo Journal. 17: 7021-32. PMID 9835654 DOI: 10.1093/emboj/17.23.7021  0.362
1998 Waltzer L, Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature. 395: 521-5. PMID 9774110 DOI: 10.1038/26785  0.393
1998 Szüts D, Eresh S, Bienz M. Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm induction. Genes & Development. 12: 2022-35. PMID 9649506 DOI: 10.1101/Gad.12.13.2022  0.681
1998 Bienz M. TCF: transcriptional activator or repressor? Current Opinion in Cell Biology. 10: 366-72. PMID 9640538 DOI: 10.1016/S0955-0674(98)80013-6  0.42
1997 Eresh S, Riese J, Jackson DB, Bohmann D, Bienz M. A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. The Embo Journal. 16: 2014-22. PMID 9155027 DOI: 10.1093/Emboj/16.8.2014  0.379
1997 Riese J, Yu X, Munnerlyn A, Eresh S, Hsu SC, Grosschedl R, Bienz M. LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell. 88: 777-87. PMID 9118221 DOI: 10.1016/S0092-8674(00)81924-8  0.39
1996 Yu X, Hoppler S, Eresh S, Bienz M. decapentaplegic, a target gene of the wingless signalling pathway in the Drosophila midgut. Development (Cambridge, England). 122: 849-58. PMID 8631263  0.36
1993 Thüringer F, Cohen SM, Bienz M. Dissection of an indirect autoregulatory response of a homeotic Drosophila gene. The Embo Journal. 12: 2419-30. PMID 8099546  0.363
1992 Tremml G, Bienz M. Induction of labial expression in the Drosophila endoderm: response elements for dpp signalling and for autoregulation. Development (Cambridge, England). 116: 447-56. PMID 1363088  0.35
1990 Immerglück K, Lawrence PA, Bienz M. Induction across germ layers in Drosophila mediated by a genetic cascade. Cell. 62: 261-8. PMID 1973634 DOI: 10.1016/0092-8674(90)90364-K  0.447
1988 Bienz M, Saari G, Tremml G, Müller J, Züst B, Lawrence PA. Differential regulation of Ultrabithorax in two germ layers of Drosophila. Cell. 53: 567-76. PMID 2897241 DOI: 10.1016/0092-8674(88)90573-9  0.435
Low-probability matches (unlikely to be authored by this person)
1985 Bienz M. Transient and developmental activation of heat-shock genes Trends in Biochemical Sciences. 10: 157-161. DOI: 10.1016/0968-0004(85)90157-4  0.297
2023 Franco-Echevarría E, Nielsen M, Schulten A, Cheema J, Morgan TE, Bienz M, Dean C. Distinct accessory roles of VEL proteins in Polycomb silencing. Genes & Development. PMID 37734835 DOI: 10.1101/gad.350814.123  0.294
1997 Bienz M. Endoderm induction in Drosophila: the nuclear targets of the inducing signals. Current Opinion in Genetics & Development. 7: 683-8. PMID 9388786 DOI: 10.1016/S0959-437X(97)80017-2  0.294
1995 Hoppler S, Bienz M. Two different thresholds of wingless signalling with distinct developmental consequences in the Drosophila midgut. The Embo Journal. 14: 5016-26. PMID 7588630  0.271
1997 Riese J, Tremml G, Bienz M. D-Fos, a target gene of Decapentaplegic signalling with a critical role during Drosophila endoderm induction. Development (Cambridge, England). 124: 3353-61. PMID 9310330  0.263
1988 Thali M, Müller MM, DeLorenzi M, Matthias P, Bienz M. Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2. Nature. 336: 598-601. PMID 2904655 DOI: 10.1038/336598a0  0.26
2006 Bienz M. Bio-sketch for oncogene review issue on Wnt signalling. Oncogene. 25: 7441. PMID 17143287 DOI: 10.1038/sj.onc.1210062  0.256
1997 Szüts D, Freeman M, Bienz M. Antagonism between EGFR and Wingless signalling in the larval cuticle of Drosophila. Development (Cambridge, England). 124: 3209-19. PMID 9272961  0.248
1994 Christen B, Bienz M. Imaginal disc silencers from Ultrabithorax: evidence for Polycomb response elements. Mechanisms of Development. 48: 255-66. PMID 7893606 DOI: 10.1016/0925-4773(94)90064-7  0.245
1992 Müller J, Bienz M. Sharp anterior boundary of homeotic gene expression conferred by the fushi tarazu protein. The Embo Journal. 11: 3653-61. PMID 1356761  0.242
2008 Shibata N, Schwarz-Romond T, Fiedler M, Butler P, Komori H, Shomura Y, Yamamoto H, Kikuchi A, Bienz M, Higuchi Y. Structural basis of dynamic polymerization of DIX domains: a revised model of Wnt signaling Acta Crystallographica Section a Foundations of Crystallography. 64: C319-C319. DOI: 10.1107/S0108767308089794  0.238
1992 Castelli-Gair J, Müller J, Bienz M. Function of an Ultrabithorax minigene in imaginal cells. Development (Cambridge, England). 114: 877-86. PMID 1352240  0.238
1995 Pöpperl H, Bienz M, Studer M, Chan SK, Aparicio S, Brenner S, Mann RS, Krumlauf R. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell. 81: 1031-42. PMID 7600572 DOI: 10.1016/S0092-8674(05)80008-X  0.237
1993 Thüringer F, Bienz M. Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling. Proceedings of the National Academy of Sciences of the United States of America. 90: 3899-903. PMID 8097881  0.236
1995 Bienz M, Müller J. Transcriptional silencing of homeotic genes in Drosophila. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 17: 775-84. PMID 8763830 DOI: 10.1002/bies.950170907  0.235
1989 Muller J, Thuringer F, Biggin M, Zust B, Bienz M. Coordinate action of a proximal homeoprotein binding site and a distal sequence confers the Ultrabithorax expression pattern in the visceral mesoderm Embo Journal. 8: 4143-4151. PMID 2574106  0.226
1994 Bienz M. Homeotic genes and positional signalling in the Drosophila viscera. Trends in Genetics : Tig. 10: 22-6. PMID 7908470 DOI: 10.1016/0168-9525(94)90015-9  0.224
2022 Fiedler M, Franco-Echevarría E, Schulten A, Nielsen M, Rutherford TJ, Yeates A, Ahsan B, Dean C, Bienz M. Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control. Cell Reports. 41: 111607. PMID 36351412 DOI: 10.1016/j.celrep.2022.111607  0.223
1992 Bienz M. Molecular mechanisms of determination in Drosophila. Current Opinion in Cell Biology. 4: 955-61. PMID 1485964  0.222
1998 Kehle J, Beuchle D, Treuheit S, Christen B, Kennison JA, Bienz M, Müller J. dMi-2, a hunchback-interacting protein that functions in polycomb repression. Science (New York, N.Y.). 282: 1897-900. PMID 9836641  0.221
1994 Hoppler S, Bienz M. Specification of a single cell type by a Drosophila homeotic gene. Cell. 76: 689-702. PMID 7907275 DOI: 10.1016/0092-8674(94)90508-8  0.211
1992 Zhang CC, Bienz M. Segmental determination in Drosophila conferred by hunchback (hb), a repressor of the homeotic gene Ultrabithorax (Ubx). Proceedings of the National Academy of Sciences of the United States of America. 89: 7511-5. PMID 1354356  0.211
2020 van Dop M, Fiedler M, Mutte S, de Keijzer J, Olijslager L, Albrecht C, Liao CY, Janson ME, Bienz M, Weijers D. DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes. Cell. PMID 32004461 DOI: 10.1016/J.Cell.2020.01.011  0.207
1989 Thali M, Müller MM, DeLorenzi M, Matthias P, Bienz M. Erratum: Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2 Nature. 337: 290-290. DOI: 10.1038/337290a0  0.204
1993 Busturia A, Bienz M. Silencers in abdominal-B, a homeotic Drosophila gene. The Embo Journal. 12: 1415-25. PMID 8096812  0.199
1992 Christen B, Bienz M. A cis-element mediating Ultrabithorax autoregulation in the central nervous system. Mechanisms of Development. 39: 73-80. PMID 1362651 DOI: 10.1016/0925-4773(92)90027-H  0.198
1996 Bienz M. Induction of the endoderm in Drosophila Seminars in Cell and Developmental Biology. 7: 113-119. DOI: 10.1006/scdb.1996.0016  0.194
1988 Bienz M, Tremml G. Domain of Ultrabithorax expression in Drosophila visceral mesoderm from autoregulation and exclusion Nature. 333: 576-578. PMID 2897631  0.193
1986 Bienz M. A CCAAT box confers cell-type-specific regulation on the Xenopus hsp70 gene in oocytes Cell. 46: 1037-1042. PMID 3757032 DOI: 10.1016/0092-8674(86)90703-8  0.193
2022 Franco-Echevarría E, Rutherford TJ, Fiedler M, Dean C, Bienz M. Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity. The Journal of Biological Chemistry. 102540. PMID 36174674 DOI: 10.1016/j.jbc.2022.102540  0.192
2007 Shibata N, Schwarz-Romond T, Fiedler M, Butler PJG, Komori H, Shomura Y, Yamamoto H, Kikuchi A, Bienz M, Higuchi Y. 1P018 Structural basis of dynamic polymerization of D1X domains: a revised model of Wnt signaling(Proteins-structure and structure-function relationship,Oral Presentations) Seibutsu Butsuri. 47: S28. DOI: 10.2142/biophys.47.S28_1  0.191
1989 Tremml G, Bienz M. An essential role of even-skipped for homeotic gene expression in the Drosophila visceral mesoderm Embo Journal. 8: 2687-2693. PMID 2573527  0.19
1988 DeLorenzi M, Ali N, Saari G, Henry C, Wilcox M, Bienz M. Evidence that the Abdominal-B r element function is conferred by a trans-regulatory homeoprotein Embo Journal. 7: 3223-3231. PMID 2903049  0.182
1991 Zhang CC, Müller J, Hoch M, Jäckle H, Bienz M. Target sequences for hunchback in a control region conferring Ultrabithorax expression boundaries Development. 113: 1171-1179. PMID 1687458  0.181
1986 Bienz M, Pelham HRB. Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter Cell. 45: 753-760. PMID 3085957 DOI: 10.1016/0092-8674(86)90789-0  0.181
1996 Hart K, Bienz M. A test for cell autonomy, based on di-cistronic messenger translation. Development (Cambridge, England). 122: 747-51. PMID 8631252  0.18
2020 Krishnan A, Berthelet J, Renaud E, Rosigkeit S, Distler U, Stawiski E, Wang J, Modrusan Z, Fiedler M, Bienz M, Tenzer S, Schad A, Roth W, Thiede B, Seshagiri S, et al. Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas. Nature Communications. 11: 2056. PMID 32345963 DOI: 10.1038/S41467-020-15955-W  0.179
1989 Tremml G, Bienz M. Homeotic gene expression in the visceral mesoderm of Drosophila embryos Embo Journal. 8: 2677-2685. PMID 2573526  0.177
1991 Ali N, Bienz M. Functional dissection of Drosophila Abdominal-B protein Mechanisms of Development. 35: 55-64. PMID 1683254 DOI: 10.1016/0925-4773(91)90041-4  0.162
1984 Bienz M. Xenopus hsp 70 genes are constitutively expressed in injected oocytes Embo Journal. 3: 2477-2483. PMID 6510409  0.149
1991 Muller J, Bienz M. Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo Embo Journal. 10: 3147-3155. PMID 1680676  0.147
2003 Bienz M. APC. Current Biology : Cb. 13: R215-6. PMID 12646143  0.146
1983 Goddard JP, Squire M, Bienz M, Smith JD. A human tRNAGlugene of high transcriptional activity Nucleic Acids Research. 11: 2551-2562. PMID 6134271 DOI: 10.1093/nar/11.9.2551  0.141
1990 Delorenzi M, Bienz M. Expression of Abdominal-B homeoproteins in Drosophila embryos Development. 108: 323-329. PMID 1972049  0.136
1982 Pelham HR, Bienz M. A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene Embo Journal. 1: 1473-1477. PMID 6327271  0.135
2020 Bienz M. Head-to-Tail Polymerization in the Assembly of Biomolecular Condensates. Cell. 182: 799-811. PMID 32822572 DOI: 10.1016/j.cell.2020.07.037  0.133
1982 Bienz M, Pelham HR. Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals Embo Journal. 1: 1583-1588. PMID 6821336  0.132
1985 GODDARD JP, McLAREN A, CARR T, BIENZ M, SMITH JD. The role of an upstream sequence in the transcription of a human transfer RNA gene Biochemical Society Transactions. 13: 754-754. DOI: 10.1042/BST0130754  0.125
2021 Harris LD, Le Pen J, Scholz N, Mieszczanek J, Vaughan N, Davis S, Berridge G, Kessler B, Bienz M, Licchesi JDF. The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1. The Journal of Biological Chemistry. 100246. PMID 33428934 DOI: 10.1074/jbc.RA120.015162  0.114
2020 Harris LD, Le Pen J, Scholz N, Mieszczanek J, Vaughan N, Davis S, Berridge G, Kessler B, Bienz M, Licchesi JDF. The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1. The Journal of Biological Chemistry. PMID 33380427 DOI: 10.1074/jbc.RA120.015162  0.114
2021 Harris LD, Le Pen J, Scholz N, Mieszczanek J, Vaughan N, Davis S, Berridge G, Kessler BM, Bienz M, Licchesi JDF. The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1. The Journal of Biological Chemistry. 296: 100246. PMID 33853758 DOI: 10.1074/jbc.RA120.015162  0.114
1981 Bienz M, Kubli E, Kohli J, deHenau S, Huez G, Marbaix G, Grosjean H. Usage of the three termination codons in a single eukaryotic cell, the Xenopus laevis oocyte. Nucleic Acids Research. 9: 3835-50. PMID 7024919 DOI: 10.1093/nar/9.15.3835  0.112
2005 von Allmen N, Bienz M, Hemphill A, Müller N. Quantitative assessment of sense and antisense transcripts from genes involved in antigenic variation (vsp genes) and encystation (cwp 1 gene) of Giardia lamblia clone GS/M-83-H7. Parasitology. 130: 389-96. PMID 15830812 DOI: 10.1017/S0031182004006742  0.111
1981 Dudler R, Schmidt T, Bienz M, Kubli E. The genes coding for tRNA Tyr of Drosophila melanogaster: localization of determination of the gene numbers. Chromosoma. 84: 49-60. PMID 6794997 DOI: 10.1007/Bf00293362  0.107
1978 Bienz M, Deak II. Microelectrophoresis of α-glycerophosphate dehydrogenase isozymes in various tissues of wild-type and mutant Drosophila Insect Biochemistry. 8: 449-455. DOI: 10.1016/0020-1790(78)90058-6  0.105
2017 Kutateladze TG, Gozani O, Bienz M, Ostankovitch M. Histone modifications for chromatin dynamics and cellular plasticity. Journal of Molecular Biology. 429: 1921-1923. PMID 28623961 DOI: 10.1016/J.Jmb.2017.06.001  0.105
1986 Bienz M. Changes in Eukaryotic Gene Expression in Response to Environmental Stress. Cell Biology.Burr G. Atkinson , David B. Walden The Quarterly Review of Biology. 61: 85-86. DOI: 10.1086/414753  0.1
1987 Bienz M, Pelham HRB. Mechanisms of Heat-Shock Gene Activation in Higher Eukaryotes Advances in Genetics. 24: 31-72. PMID 3324701 DOI: 10.1016/S0065-2660(08)60006-1  0.098
1980 Bienz M, Kubli E, Kohli J, de Henau S, Grosjean H. Nonsense suppression in eukaryotes: the use of the Xenopus oocyte as an in vivo assay system. Nucleic Acids Research. 8: 5169-78. PMID 7465411  0.09
2002 Keller N, Naguleswaran A, Cannas A, Vonlaufen N, Bienz M, Björkman C, Bohne W, Hemphill A. Identification of a Neospora caninum microneme protein (NcMIC1) which interacts with sulfated host cell surface glycosaminoglycans. Infection and Immunity. 70: 3187-98. PMID 12011014 DOI: 10.1128/IAI.70.6.3187-3198.2002  0.09
1984 GODDARD JP, BIENZ M, SQUIRE M, SMITH JD. Studies on a human tRNA gene Biochemical Society Transactions. 12: 282-282. DOI: 10.1042/BST0120282  0.09
1981 Bienz M, Kubli E. Wild-type tRNAreads the TMV RNA stop codon, but Q base-modified tRNAdoes not. Nature. 294: 188-190. PMID 29451243 DOI: 10.1038/294188a0  0.086
2001 Bienz M, Siles-Lucas M, Müller N. Use of a novel DNA melting profile assay for the identification of PCR-amplified genomic sequences encoding for variant-specific surface proteins from the clonal GS/M-83-H7 line of Giardia lamblia. Parasitology Research. 87: 1011-5. PMID 11763430  0.084
2001 Bienz M, Siles-Lucas M, Wittwer P, Müller N. vsp gene expression by Giardia lamblia clone GS/M-83-H7 during antigenic variation in vivo and in vitro. Infection and Immunity. 69: 5278-85. PMID 11500396 DOI: 10.1128/IAI.69.9.5278-5285.2001  0.082
1982 Bienz M, Gurdon JB. The heat-shock response in Xenopus oocytes is controlled at the translational level. Cell. 29: 811-9. PMID 6891290 DOI: 10.1016/0092-8674(82)90443-3  0.079
1984 Bienz M. Developmenal control of the heat shock response in Xenopus Proceedings of the National Academy of Sciences of the United States of America. 81: 3138-3142. PMID 6203112  0.078
2001 Bienz M, Wittwer P, Zimmermann V, Müller N. Molecular characterisation of a predominant antigenic region of Giardia lamblia variant surface protein H7. International Journal For Parasitology. 31: 827-32. PMID 11403775 DOI: 10.1016/S0020-7519(01)00182-5  0.065
2005 Bienz M, Ludwig M, Leibundgut EO, Mueller BU, Ratschiller D, Solenthaler M, Fey MF, Pabst T. Risk assessment in patients with acute myeloid leukemia and a normal karyotype. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1416-24. PMID 15746041 DOI: 10.1158/1078-0432.CCR-04-1552  0.061
1988 Chen PS, Stumm-Zollinger E, Aigaki T, Balmer J, Bienz M, Böhlen P. A male accessory gland peptide that regulates reproductive behavior of female D. melanogaster. Cell. 54: 291-8. PMID 3135120 DOI: 10.1016/0092-8674(88)90192-4  0.06
2003 Bienz M, Dai WJ, Welle M, Gottstein B, Müller N. Interleukin-6-deficient mice are highly susceptible to Giardia lamblia infection but exhibit normal intestinal immunoglobulin A responses against the parasite. Infection and Immunity. 71: 1569-73. PMID 12595479 DOI: 10.1128/IAI.71.3.1569-1573.2003  0.055
1982 Deak II, Bellamy PR, Bienz M. Mutations affecting the indirect flight muscles of Drosophila melanogaster Journal of Embryology and Experimental Morphology. 61-81.  0.052
2015 Bienz M, Hueber PA, Trudeau V, Alenizi AM, Valdivieso R, Alom M, Balbay MD, Canda AE, Mouraviev V, Albala DM, El-Hakim A, Trinh QD, Latour M, Saad F, Zorn KC. Prevalence and risk factors of contralateral extraprostatic extension in men undergoing radical prostatectomy for unilateral disease at biopsy: A global multi-institutional experience. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 9: E434-8. PMID 26279712 DOI: 10.5489/Cuaj.2786  0.046
2015 Bienz M, Saad F. Androgen-deprivation therapy and bone loss in prostate cancer patients: a clinical review. Bonekey Reports. 4: 716. PMID 26131363 DOI: 10.1038/Bonekey.2015.85  0.044
2008 Bienz M. Strong links in textiles exist between Pakistan and Switzerland Pakistan Textile Journal. 57: 60.  0.039
2014 Tholomier C, Bienz M, Hueber PA, Trinh QD, Hakim AE, Alhathal N, Lebeau T, Benayoun S, Valdivieso R, Liberman D, Saad F, Lattouf JB, Widmer H, Begin L, Latour M, et al. Oncological and functional outcomes of 722 robot-assisted radical prostatectomy (RARP) cases: The largest Canadian 5-year experience. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 8: 195-201. PMID 25024790 DOI: 10.5489/Cuaj.2016  0.035
2015 Bienz M, Saad F. Management of bone metastases in prostate cancer: a review. Current Opinion in Supportive and Palliative Care. 9: 261-7. PMID 26262831 DOI: 10.1097/Spc.0000000000000157  0.031
2015 Bienz M, Drullinsky D, Stevens LM, Bracco D, Noiseux N. Microcirculatory response during on-pump versus off-pump coronary artery bypass graft surgery. Perfusion. PMID 26091812 DOI: 10.1177/0267659115590481  0.031
1980 Deak II, Rähmi A, Bellamy PR, Bienz M, Blumer A, Fenner E, Gollin M, Ramp T, Reinhardt C, Dübendorfer A, Cotton B. Developmental and genetic studies of the indirect flight muscles of Drosophila melanogaster Basic Life Sciences. 16: 183-192. PMID 6779791  0.029
2014 James H, Aleksic I, Bienz MN, Pieczonka C, Iannotta P, Albala D, Mariados N, Mouraviev V, Saad F. Comparison of fracture risk assessment tool score to bone mineral density for estimating fracture risk in patients with advanced prostate cancer on androgen deprivation therapy. Urology. 84: 164-8. PMID 24976229 DOI: 10.1016/J.Urology.2013.12.071  0.022
1981 Bienz M, Kubli E. Wild-type tRNA(G/Tyr) reads the TMV RNA stop codon, but Q base-modified tRNA(Q/Tyr) does not Nature. 294: 188-190.  0.021
2015 Lavigueur-Blouin H, Noriega AC, Valdivieso R, Hueber PA, Bienz M, Alhathal N, Latour M, Trinh QD, El-Hakim A, Zorn KC. Predictors of early continence following robot-assisted radical prostatectomy. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 9: e93-7. PMID 25737770 DOI: 10.5489/cuaj.2086  0.02
2015 Alenizi AM, Valdivieso R, Rajih E, Meskawi M, Toarta C, Bienz M, Azizi M, Hueber PA, Lavigueur-Blouin H, Trudeau V, Trinh QD, El-Hakim A, Zorn KC. Factors predicting prolonged operative time for individual surgical steps of robot-assisted radical prostatectomy (RARP): A single surgeon's experience. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 9: E417-22. PMID 26279709 DOI: 10.5489/cuaj.2805  0.019
2004 von Allmen N, Bienz M, Hemphill A, Müller N. Experimental infections of neonatal mice with cysts of Giardia lamblia clone GS/M-83-H7 are associated with an antigenic reset of the parasite. Infection and Immunity. 72: 4763-71. PMID 15271938 DOI: 10.1128/IAI.72.8.4763-4771.2004  0.019
2015 Alenizi AM, Bienz M, Rajih E, Alesawi A, Al-Hathal N, Benayoun S, Lebeau T, Zorn KC, El-Hakim A. Uroflow Stop Test and Potency Recovery: A Surrogate for Pelvic Floor Integrity Post Robotic-Assisted Radical Prostatectomy? Urology. 86: 766-71. PMID 26254170 DOI: 10.1016/j.urology.2015.05.041  0.014
2014 Bienz M, Hueber PA, Al-Hathal N, McCormack M, Bhojani N, Trinh QD, Zorn KC. Accuracy of transrectal ultrasonography to evaluate pathologic prostate weight: correlation with various prostate size groups. Urology. 84: 169-74. PMID 24976231 DOI: 10.1016/j.urology.2014.02.022  0.012
2015 Hueber PA, Bienz MN, Valdivieso R, Lavigueur-Blouin H, Misrai V, Rutman M, Te AE, Chughtai B, Barber NJ, Emara AM, Munver R, Trinh QD, Zorn KC. Photoselective Vaporization of the Prostate for Benign Prostatic Hyperplasia Using the 180 Watt System: Multicenter Study of the Impact of Prostate Size on Safety and Outcomes. The Journal of Urology. 194: 462-9. PMID 25849599 DOI: 10.1016/j.juro.2015.03.113  0.01
2014 Hueber P, Bienz M, Liberman D, Misrai V, Rutman M, Te A, Chughtai B, Barber N, Emara A, Gonzalez R, Munver R, Zorn K. [In Process Citation]. ProgrèS En Urologie : Journal De L'Association FrançAise D'Urologie Et De La SociéTé FrançAise D'Urologie. 24: 878. PMID 26461732 DOI: 10.1016/j.purol.2014.08.206  0.01
2014 Ben-Zvi T, Hueber PA, Valdivieso R, Azzizi M, Tholomier C, Bienz M, Bhojani N, Trinh QD, Zorn KC. Urological resident exposure to transurethral surgical options for BPH management in 2012-2013: A pan-Canadian survey. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 8: 54-60. PMID 24578746 DOI: 10.5489/cuaj.1647  0.01
2003 Müller N, Zimmermann V, Forster U, Bienz M, Gottstein B, Welle M. PCR-based detection of canine Leishmania infections in formalin-fixed and paraffin-embedded skin biopsies: elaboration of a protocol for quality assessment of the diagnostic amplification reaction. Veterinary Parasitology. 114: 223-9. PMID 12788257 DOI: 10.1016/S0304-4017(03)00139-0  0.01
1986 Weston K, Cozens A, Nelson HCM, Fairall L, Amos L, Mengle-Gaw L, Lefebvre FA, Clark MJ, Kenyon C, Bienz M, Breeden L, Schnabel H, Robinson M, Albertson D, Greenwald I, et al. Sexist ads Nature. 321: 106. DOI: 10.1038/321106b0  0.01
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