Kevin J. Yarema - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering
Website:
https://engineering.jhu.edu/faculty/kevin-yarema/

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Du J, Agatemor C, Saeui CT, Bhattacharya R, Jia X, Yarema KJ. Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified -Acetylmannosamine (ManNAc) Analogs. Cells. 10. PMID 33673061 DOI: 10.3390/cells10020377  1
2020 Mertz JL, Sun S, Yin B, Hu Y, Bhattacharya R, Bettenbaugh MJ, Yarema KJ, Zhang H. Comparison of Three Glycoproteomic Methods for the Analysis of the Secretome of CHO Cells Treated with 1,3,4--BuManNAc. Bioengineering (Basel, Switzerland). 7. PMID 33182731 DOI: 10.3390/bioengineering7040144  1
2020 Stabach PR, Zimmerman K, Adame A, Kavanagh D, Saeui CT, Agatemor C, Gray S, Cao W, De La Cruz EM, Yarema KJ, Braddock DT. Improving the Pharmacodynamics and In Vivo Activity of ENPP1-Fc Through Protein and Glycosylation Engineering. Clinical and Translational Science. PMID 33064927 DOI: 10.1111/cts.12887  1
2020 Saeui CT, Cho KC, Dharmarha V, Nairn AV, Galizzi M, Shah SR, Gowda P, Park M, Austin M, Clarke A, Cai E, Buettner MJ, Ariss R, Moremen KW, Zhang H, ... Yarema KJ, et al. Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression. Frontiers in Chemistry. 8: 13. PMID 32117864 DOI: 10.3389/Fchem.2020.00013  1
2019 Agatemor C, Buettner MJ, Ariss R, Muthiah K, Saeui CT, Yarema KJ. Exploiting metabolic glycoengineering to advance healthcare. Nature Reviews. Chemistry. 3: 605-620. PMID 31777760 DOI: 10.1038/s41570-019-0126-y  1
2018 Buettner MJ, Shah SR, Saeui CT, Ariss R, Yarema KJ. Improving Immunotherapy Through Glycodesign. Frontiers in Immunology. 9: 2485. PMID 30450094 DOI: 10.3389/fimmu.2018.02485  1
2018 Wang Q, Chung CY, Yang W, Yang G, Chough S, Chen Y, Yin B, Bhattacharya R, Hu Y, Saeui CT, Yarema KJ, Betenbaugh MJ, Zhang H. Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production. Biotechnology Journal. e1800186. PMID 30221828 DOI: 10.1002/Biot.201800186  1
2018 Saeui CT, Nairn AV, Galizzi M, Douville C, Gowda P, Park M, Dharmarha V, Shah SR, Clarke A, Austin M, Moremen KW, Yarema KJ. Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes. Plos One. 13: e0195812. PMID 29847599 DOI: 10.1371/Journal.Pone.0195812  1
2018 Meyer RA, Mathew MP, Ben-Akiva E, Sunshine JC, Shmueli RB, Ren Q, Yarema KJ, Green JJ. Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation. Acta Biomaterialia. PMID 29631048 DOI: 10.1016/j.actbio.2018.03.056  1
2018 Yin B, Wang Q, Chung CY, Ren X, Bhattacharya R, Yarema KJ, Betenbaugh MJ. Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells. Biotechnology and Bioengineering. PMID 29427449 DOI: 10.1002/Bit.26560  1
2018 Dharmarha V, Saeui C, Song J, Li H, Katz H, Yarema K. AB107. P081. Metabolic oligosaccharide engineering of pancreatic cells: measurement of sialylation and identification of sialylated glycoproteins Annals of Pancreatic Cancer. 1: AB107-AB107. DOI: 10.21037/apc.2018.ab107  0.01
2017 Kim H, Shin K, Park OK, Choi D, Kim HD, Baik S, Lee SH, Kwon SH, Yarema KJ, Hong J, Hyeon T, Hwang NS. General and Facile Coating of Single Cells via Mild Reduction. Journal of the American Chemical Society. PMID 29281277 DOI: 10.1021/Jacs.7B08440  0.01
2017 Saeui C, Liu L, Urias E, Morrissette-McAlmon J, Bhattacharya R, Yarema KJ. Pharmacological, Physiochemical, and Drug-Relevant Biological Properties of Short Chain Fatty Acid Hexosamine Analogs used in Metabolic Glycoengineering. Molecular Pharmaceutics. PMID 28853901 DOI: 10.1021/acs.molpharmaceut.7b00525  1
2017 Song Y, Kilburn D, Song JH, Cheng Y, Saeui CT, Cheung DG, Croce CM, Yarema KJ, Meltzer SJ, Liu KJ, Wang TH. Determination of absolute expression profiles using multiplexed miRNA analysis. Plos One. 12: e0180988. PMID 28704432 DOI: 10.1371/Journal.Pone.0180988  1
2017 Yin B, Wang Q, Chung CY, Bhattacharya R, Ren X, Tang J, Yarema KJ, Betenbaugh MJ. A novel sugar analog enhances sialic acid production and biotherapeutic sialylation in CHO cells. Biotechnology and Bioengineering. PMID 28295160 DOI: 10.1002/Bit.26291  1
2017 Mathew M, Tan E, Labonte JW, Shah S, Saeui CT, Liu L, Bhattacharya R, Bovonratwet P, Gray JJ, Yarema K. GLYCOENGINEERING OF ESTERASE ACTIVITY THROUGH METABOLIC FLUX-BASED MODULATION OF SIALIC ACID. Chembiochem : a European Journal of Chemical Biology. PMID 28218815 DOI: 10.1002/Cbic.201600698  1
2016 Badr HA, AlSadek DM, El-Houseini ME, Saeui CT, Mathew MP, Yarema KJ, Ahmed H. Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example. Biomaterials. 116: 158-173. PMID 27926828 DOI: 10.1016/j.biomaterials.2016.11.044  1
2016 Mathew MP, Tan E, Saeui CT, Bovonratwet P, Sklar S, Bhattacharya R, Yarema KJ. Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells. Oncotarget. PMID 27613843 DOI: 10.18632/oncotarget.11582  1
2016 Kim C, Shores L, Guo Q, Aly A, Jeon OH, Kim DH, Bernstein N, Bhattacharya R, Chae JJ, Yarema KJ, Elisseeff JH. Electrospun microfiber scaffolds with anti-inflammatory tri-butanoylated N-acetyl-D-glucosamine promote cartilage regeneration. Tissue Engineering. Part A. PMID 27019285 DOI: 10.1089/Ten.Tea.2015.0469  1
2016 Saeui CT, Yarema K. Abstract LB-054: Small molecule inhibitors of the hexosamine biosynthetic pathway and the cancer O-GlcNAcome Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-054  1
2015 Kim C, Jeon OH, Kim DH, Chae JJ, Shores L, Bernstein N, Bhattacharya R, Coburn JM, Yarema KJ, Elisseeff JH. Local delivery of a carbohydrate analog for reducing arthritic inflammation and rebuilding cartilage. Biomaterials. 83: 93-101. PMID 26773662 DOI: 10.1016/J.Biomaterials.2015.12.029  1
2015 Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H. Lectin staining and Western blot data showing differential sialylation of nutrient-deprived cancer cells to sialic acid supplementation. Data in Brief. 5: 481-488. PMID 26629491 DOI: 10.1016/j.dib.2015.09.043  1
2015 Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H. Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation. Biomaterials. 70: 23-36. PMID 26295436 DOI: 10.1016/j.biomaterials.2015.08.020  1
2015 Mishra S, Bedja D, Amuzie C, Foss CA, Pomper MG, Bhattacharya R, Yarema KJ, Chatterjee S. Improved intervention of atherosclerosis and cardiac hypertrophy through biodegradable polymer-encapsulated delivery of glycosphingolipid inhibitor. Biomaterials. PMID 26111596 DOI: 10.1016/J.Biomaterials.2015.06.001  1
2015 Saeui CT, Mathew MP, Liu L, Urias E, Yarema KJ. Cell Surface and Membrane Engineering: Emerging Technologies and Applications. Journal of Functional Biomaterials. 6: 454-85. PMID 26096148 DOI: 10.3390/jfb6020454  1
2015 Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H. Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical Proteomics. 12: 11. PMID 25987888 DOI: 10.1186/s12014-015-9083-8  1
2015 Saeui CT, Urias E, Liu L, Mathew MP, Yarema KJ. Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications. Glycoconjugate Journal. 32: 425-41. PMID 25931032 DOI: 10.1007/s10719-015-9583-9  1
2015 Mathew MP, Tan E, Saeui CT, Bovonratwet P, Liu L, Bhattacharya R, Yarema KJ. Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib. Bioorganic & Medicinal Chemistry Letters. 25: 1223-7. PMID 25690786 DOI: 10.1016/j.bmcl.2015.01.060  1
2015 Remy AJ. News tools of screening viral hepatitis in real life: The French model of care Journal of Liver. 4. DOI: 10.4172/2167-0889.S1.002  0.01
2015 Mathew MP, Tan E, Saeui CT, Bovonratwet P, Liu L, Bhattacharya R, Yarema KJ. Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib Bioorganic and Medicinal Chemistry Letters. 25: 1223-1227. DOI: 10.1016/j.bmcl.2015.01.060  1
2014 Gibson M, Li H, Coburn J, Moroni L, Nahas Z, Bingham C, Yarema K, Elisseeff J. Intra-articular delivery of glucosamine for treatment of experimental osteoarthritis created by a medial meniscectomy in a rat model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 302-9. PMID 24600703 DOI: 10.1002/Jor.22445  1
2014 Du J, Tan E, Kim HJ, Zhang A, Bhattacharya R, Yarema KJ. Comparative evaluation of chitosan, cellulose acetate, and polyethersulfone nanofiber scaffolds for neural differentiation. Carbohydrate Polymers. 99: 483-90. PMID 24274534 DOI: 10.1016/j.carbpol.2013.08.050  1
2014 Alberch L, Yarema KJ. Bioconjugation Reactions in Living Cells: Development, Advances, and Applications of Glycan-Specific Technologies Micro-and Nanoengineering of the Cell Surface. 43-62. DOI: 10.1016/B978-1-4557-3146-6.00003-9  1
2013 Coburn JM, Wo L, Bernstein N, Bhattacharya R, Aich U, Bingham CO, Yarema KJ, Elisseeff JH. Short-chain fatty acid-modified hexosamine for tissue-engineering osteoarthritic cartilage. Tissue Engineering. Part A. 19: 2035-44. PMID 23638885 DOI: 10.1089/Ten.Tea.2012.0317  1
2013 Coburn JM, Bernstein N, Bhattacharya R, Aich U, Yarema KJ, Elisseeff JH. Differential response of chondrocytes and chondrogenic-induced mesenchymal stem cells to C1-OH tributanoylated N-acetylhexosamines. Plos One. 8: e58899. PMID 23516573 DOI: 10.1371/Journal.Pone.0058899  1
2013 Shah P, Yang S, Sun S, Aiyetan P, Yarema KJ, Zhang H. Mass spectrometric analysis of sialylated glycans with use of solid-phase labeling of sialic acids. Analytical Chemistry. 85: 3606-13. PMID 23445396 DOI: 10.1021/Ac3033867  1
2013 Bennun SV, Yarema KJ, Betenbaugh MJ, Krambeck FJ. Integration of the transcriptome and glycome for identification of glycan cell signatures. Plos Computational Biology. 9: e1002813. PMID 23326219 DOI: 10.1371/Journal.Pcbi.1002813  1
2013 Du J, Almaraz RT, Tan E, Yarema KJ. Metabolic glycoengineering of sialic acids Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease. 476-511. DOI: 10.2174/9781608053865113010017  1
2012 Mathew MP, Tan E, Shah S, Bhattacharya R, Adam Meledeo M, Huang J, Espinoza FA, Yarema KJ. Extracellular and intracellular esterase processing of SCFA-hexosamine analogs: implications for metabolic glycoengineering and drug delivery. Bioorganic & Medicinal Chemistry Letters. 22: 6929-33. PMID 23041156 DOI: 10.1016/j.bmcl.2012.09.017  1
2012 Almaraz RT, Tian Y, Bhattarcharya R, Tan E, Chen SH, Dallas MR, Chen L, Zhang Z, Zhang H, Konstantopoulos K, Yarema KJ. Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis. Molecular & Cellular Proteomics : McP. 11: M112.017558. PMID 22457533 DOI: 10.1074/Mcp.M112.017558  1
2012 Almaraz RT, Aich U, Khanna HS, Tan E, Bhattacharya R, Shah S, Yarema KJ. Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations. Biotechnology and Bioengineering. 109: 992-1006. PMID 22068462 DOI: 10.1002/bit.24363  1
2012 Almaraz RT, Mathew MP, Tan E, Yarema KJ. Metabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation. Annals of Biomedical Engineering. 40: 806-15. PMID 22037949 DOI: 10.1007/s10439-011-0450-y  1
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Yarema K, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  1
2011 Granell AE, Palter KB, Akan I, Aich U, Yarema KJ, Betenbaugh MJ, Thornhill WB, Recio-Pinto E. DmSAS is required for sialic acid biosynthesis in cultured Drosophila third instar larvae CNS neurons. Acs Chemical Biology. 6: 1287-95. PMID 21919466 DOI: 10.1021/Cb200238K  1
2011 Du J, Che PL, Aich U, Tan E, Kim HJ, Sampathkumar SG, Yarema KJ. Deciphering glycan linkages involved in Jurkat cell interactions with gold-coated nanofibers via sugar-displayed thiols. Bioorganic & Medicinal Chemistry Letters. 21: 4980-4. PMID 21684742 DOI: 10.1016/j.bmcl.2011.05.044  1
2011 Du J, Che PL, Wang ZY, Aich U, Yarema KJ. Designing a binding interface for control of cancer cell adhesion via 3D topography and metabolic oligosaccharide engineering. Biomaterials. 32: 5427-37. PMID 21549424 DOI: 10.1016/j.biomaterials.2011.04.005  1
2011 Meledeo MA, Paruchuri VDP, Du J, Wang Z, Yarema KJ. Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition Carbohydrate Recognition: Biological Problems, Methods, and Applications. 1-32. DOI: 10.1002/9781118017586.ch1  1
2010 Tan E, Almaraz RT, Khanna HS, Du J, Yarema KJ. Experimental Design Considerations for In Vitro Non-Natural Glycan Display via Metabolic Oligosaccharide Engineering. Current Protocols in Chemical Biology. 2: 171-94. PMID 23839968 DOI: 10.1002/9780470559277.ch100059  1
2010 Wang Z, Che PL, Du J, Ha B, Yarema KJ. Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drug candidate ZM241385. Plos One. 5: e13883. PMID 21079735 DOI: 10.1371/journal.pone.0013883  1
2010 Lim SH, Liu XY, Song H, Yarema KJ, Mao HQ. The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells. Biomaterials. 31: 9031-9. PMID 20797783 DOI: 10.1016/J.Biomaterials.2010.08.021  1
2010 Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconjugate Journal. 27: 445-59. PMID 20458533 DOI: 10.1007/S10719-010-9292-3  1
2010 Du J, Yarema KJ. Carbohydrate engineered cells for regenerative medicine. Advanced Drug Delivery Reviews. 62: 671-82. PMID 20117158 DOI: 10.1016/j.addr.2010.01.003  1
2009 Wang Z, Du J, Che PL, Meledeo MA, Yarema KJ. Hexosamine analogs: from metabolic glycoengineering to drug discovery Current Opinion in Chemical Biology. 13: 565-572. PMID 19747874 DOI: 10.1016/j.cbpa.2009.08.001  1
2009 Du J, Meledeo MA, Wang Z, Khanna HS, Paruchuri VD, Yarema KJ. Metabolic glycoengineering: sialic acid and beyond. Glycobiology. 19: 1382-401. PMID 19675091 DOI: 10.1093/glycob/cwp115  1
2009 Wang Z, Sarje A, Che PL, Yarema KJ. Moderate strength (0.23-0.28 T) static magnetic fields (SMF) modulate signaling and differentiation in human embryonic cells. Bmc Genomics. 10: 356. PMID 19653909 DOI: 10.1186/1471-2164-10-356  1
2009 Krambeck FJ, Bennun SV, Narang S, Choi S, Yarema KJ, Betenbaugh MJ. A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data. Glycobiology. 19: 1163-75. PMID 19506293 DOI: 10.1093/Glycob/Cwp081  1
2009 Elmouelhi N, Aich U, Paruchuri VD, Meledeo MA, Campbell CT, Wang JJ, Srinivas R, Khanna HS, Yarema KJ. Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. Journal of Medicinal Chemistry. 52: 2515-30. PMID 19326913 DOI: 10.1021/jm801661m  1
2009 Atukorale PU, Choi SS, Aich U, Campbell CT, Meledeo MA, Yarema KJ. Chemical Biology of Cell Surface Oligosaccharides Protein Targeting With Small Molecules: Chemical Biology Techniques and Applications. 189-222. DOI: 10.1002/9780470495018.ch10  1
2008 Campbell CT, Aich U, Weier CA, Wang JJ, Choi SS, Wen MM, Maisel K, Sampathkumar SG, Yarema KJ. Targeting pro-invasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells. Journal of Medicinal Chemistry. 51: 8135-47. PMID 19053749 DOI: 10.1021/jm800873k  1
2008 Kim EJ, Shin HY, Park S, Sung D, Jon S, Sampathkumar SG, Yarema KJ, Choi SY, Kim K. Electrochemically active, anti-biofouling polymer adlayers on indium-tin-oxide electrodes. Chemical Communications (Cambridge, England). 3543-5. PMID 18654707 DOI: 10.1039/b804816a  1
2008 Aich U, Campbell CT, Elmouelhi N, Weier CA, Sampathkumar SG, Choi SS, Yarema KJ. Regioisomeric SCFA attachment to hexosamines separates metabolic flux from cytotoxicity and MUC1 suppression. Acs Chemical Biology. 3: 230-40. PMID 18338853 DOI: 10.1021/cb7002708  1
2007 Daubeuf S, Aucher A, Sampathkumar SG, Preville X, Yarema KJ, Hudrisier D. Chemical labels metabolically installed into the glycoconjugates of the target cell surface can be used to track lymphocyte/target cell interplay via trogocytosis: comparisons with lipophilic dyes and biotin. Immunological Investigations. 36: 687-712. PMID 18161525 DOI: 10.1080/08820130701674596  1
2007 Campbell CT, Sampathkumar SG, Yarema KJ. Metabolic oligosaccharide engineering: perspectives, applications, and future directions. Molecular Biosystems. 3: 187-94. PMID 17308665 DOI: 10.1039/b614939c  1
2007 Faure C, Chalazonitis A, Rhéaume C, Bouchard G, Sampathkumar SG, Yarema KJ, Gershon MD. Gangliogenesis in the enteric nervous system: roles of the polysialylation of the neural cell adhesion molecule and its regulation by bone morphogenetic protein-4. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 44-59. PMID 16958105 DOI: 10.1002/Dvdy.20943  1
2006 Sampathkumar SG, Jones MB, Yarema KJ. Metabolic expression of thiol-derivatized sialic acids on the cell surface and their quantitative estimation by flow cytometry. Nature Protocols. 1: 1840-51. PMID 17487167 DOI: 10.1038/nprot.2006.252  1
2006 Sampathkumar SG, Li AV, Yarema KJ. Synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. Nature Protocols. 1: 2377-85. PMID 17406481 DOI: 10.1038/nprot.2006.319  1
2006 Sampathkumar SG, Jones MB, Meledeo MA, Campbell CT, Choi SS, Hida K, Gomutputra P, Sheh A, Gilmartin T, Head SR, Yarema KJ. Targeting glycosylation pathways and the cell cycle: sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. Chemistry & Biology. 13: 1265-75. PMID 17185222 DOI: 10.1016/J.Chembiol.2006.09.016  1
2006 Sampathkumar SG, Li A, Yarema KJ. Sialic acid and the central nervous system: perspectives on biological functions, detection, imaging methods and manipulation. Cns & Neurological Disorders Drug Targets. 5: 425-40. PMID 16918394  1
2006 Varghese S, Theprungsirikul P, Sahani S, Hwang N, Yarema KJ, Elisseeff JH. Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression. Osteoarthritis and Cartilage. 15: 59-68. PMID 16849037 DOI: 10.1016/J.Joca.2006.06.008  0.04
2006 Wang Z, Sun Z, Li AV, Yarema KJ. Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation. The Journal of Biological Chemistry. 281: 27016-28. PMID 16847058 DOI: 10.1074/jbc.M604903200  1
2006 Sampathkumar SG, Li AV, Jones MB, Sun Z, Yarema KJ. Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology. Nature Chemical Biology. 2: 149-52. PMID 16474386 DOI: 10.1038/nchembio770  1
2006 Sampathkumar SG, Campbell CT, Weier C, Yarema KJ. Short-chain fatty acid-hexosamine cancer prodrugs: The sugar matters! Drugs of the Future. 31: 1099-1116. DOI: 10.1358/dof.2006.031.12.1049173  1
2006 Loo Y, Sampathkumar S, Atukorale PU, Yarema KJ, Leong KW. 356. Engineering of Cell Surface Sialic Acids for Polymeric Gene Delivery Molecular Therapy. 13: S135-S136. DOI: 10.1016/J.Ymthe.2006.08.414  0.01
2005 Yarema KJ, Sun Z. A photochemical snapshot of CD22 binding. Nature Chemical Biology. 1: 69-70. PMID 16408000 DOI: 10.1038/nchembio0705-69  1
2005 Campbell CT, Yarema KJ. Large-scale approaches for glycobiology. Genome Biology. 6: 236. PMID 16277754 DOI: 10.1186/gb-2005-6-11-236  1
2005 Salama I, Hinderlich S, Shlomai Z, Eisenberg I, Krause S, Yarema K, Argov Z, Lochmuller H, Reutter W, Dabby R, Sadeh M, Ben-Bassat H, Mitrani-Rosenbaum S. No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation. Biochemical and Biophysical Research Communications. 328: 221-6. PMID 15670773 DOI: 10.1016/J.Bbrc.2004.12.157  1
2005 Sampathkumar SG, Yarema KJ. Targeting cancer cells with dendrimers. Chemistry & Biology. 12: 5-6. PMID 15664507 DOI: 10.1016/j.chembiol.2004.12.007  1
2004 Kim EJ, Jones MB, Rhee JK, Sampathkumar SG, Yarema KJ. Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications. Biotechnology Progress. 20: 1674-82. PMID 15575698 DOI: 10.1021/Bp049841Q  1
2004 Murrell MP, Yarema KJ, Levchenko A. The systems biology of glycosylation. Chembiochem : a European Journal of Chemical Biology. 5: 1334-47. PMID 15457533 DOI: 10.1002/Cbic.200400143  1
2004 Hinderlich S, Salama I, Eisenberg I, Potikha T, Mantey LR, Yarema KJ, Horstkorte R, Argov Z, Sadeh M, Reutter W, Mitrani-Rosenbaum S. The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy. Febs Letters. 566: 105-9. PMID 15147877 DOI: 10.1016/J.Febslet.2004.04.013  1
2004 Kim EJ, Sampathkumar SG, Jones MB, Rhee JK, Baskaran G, Goon S, Yarema KJ. Characterization of the metabolic flux and apoptotic effects of O-hydroxyl- and N-acyl-modified N-acetylmannosamine analogs in Jurkat cells. The Journal of Biological Chemistry. 279: 18342-52. PMID 14966124 DOI: 10.1074/Jbc.M400205200  1
2004 Jones MB, Teng H, Rhee JK, Lahar N, Baskaran G, Yarema KJ. Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids. Biotechnology and Bioengineering. 85: 394-405. PMID 14755557 DOI: 10.1002/bit.10901  1
2003 Tong L, Baskaran G, Jones MB, Rhee JK, Yarema KJ. Glycosylation changes as markers for the diagnosis and treatment of human disease. Biotechnology & Genetic Engineering Reviews. 20: 199-244. PMID 14997853  1
2003 Viswanathan K, Lawrence S, Hinderlich S, Yarema KJ, Lee YC, Betenbaugh MJ. Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them. Biochemistry. 42: 15215-25. PMID 14690432 DOI: 10.1021/Bi034994S  1
2003 Luchansky SJ, Yarema KJ, Takahashi S, Bertozzi CR. GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism. The Journal of Biological Chemistry. 278: 8035-42. PMID 12499362 DOI: 10.1074/Jbc.M212127200  1
2002 Yarema KJ. New directions in carbohydrate engineering: a metabolic substrate-based approach to modify the cell surface display of sialic acids. Biotechniques. 31: 384-93. PMID 11515375 DOI: 10.2144/01312RV02  0.01
2001 Jacobs CL, Goon S, Yarema KJ, Hinderlich S, Hang HC, Chai DH, Bertozzi CR. Substrate specificity of the sialic acid biosynthetic pathway. Biochemistry. 40: 12864-74. PMID 11669623 DOI: 10.1021/Bi010862S  1
2001 Yarema KJ, Bertozzi CR. Characterizing glycosylation pathways. Genome Biology. 2: REVIEWS0004. PMID 11387039 DOI: 10.1186/Gb-2001-2-5-Reviews0004  1
2001 Yarema KJ, Goon S, Bertozzi CR. Metabolic selection of glycosylation defects in human cells. Nature Biotechnology. 19: 553-8. PMID 11385460 DOI: 10.1038/89305  1
2000 Jacobs CL, Yarema KJ, Mahal LK, Nauman DA, Charters NW, Bertozzi CR. Metabolic labeling of glycoproteins with chemical tags through unnatural sialic acid biosynthesis. Methods in Enzymology. 327: 260-75. PMID 11044989 DOI: 10.1016/S0076-6879(00)27282-0  1
1999 Lemieux GA, Yarema KJ, Jacobs CL, Bertozzi CR. Exploiting differences in sialoside expression for selective targeting of MRI contrast reagents Journal of the American Chemical Society. 121: 4278-4279. DOI: 10.1021/Ja984228M  1
1998 Yarema KJ, Mahal LK, Bruehl RE, Rodriguez EC, Bertozzi CR. Metabolic delivery of ketone groups to sialic acid residues. Application To cell surface glycoform engineering. The Journal of Biological Chemistry. 273: 31168-79. PMID 9813021 DOI: 10.1074/Jbc.273.47.31168  1
1998 Yarema KJ, Bertozzi CR. Chemical approaches to glycobiology and emerging carbohydrate-based therapeutic agents. Current Opinion in Chemical Biology. 2: 49-61. PMID 9667919 DOI: 10.1016/S1367-5931(98)80035-5  1
1997 Mahal LK, Yarema KJ, Bertozzi CR. Engineering chemical reactivity on cell surfaces through oligosaccharide biosynthesis. Science (New York, N.Y.). 276: 1125-8. PMID 9173543 DOI: 10.1126/Science.276.5315.1125  1
1996 Rink SM, Yarema KJ, Solomon MS, Paige LA, Tadayoni-Rebek BM, Essigmann JM, Croy RG. Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 15063-8. PMID 8986764 DOI: 10.1073/Pnas.93.26.15063  1
1996 Moggs JG, Yarema KJ, Essigmann JM, Wood RD. Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct. The Journal of Biological Chemistry. 271: 7177-86. PMID 8636155 DOI: 10.1074/Jbc.271.12.7177  1
1995 Yarema KJ, Lippard SJ, Essigmann JM. Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II). Nucleic Acids Research. 23: 4066-72. PMID 7479066 DOI: 10.1093/Nar/23.20.4066  1
1995 Yarema KJ. Comparative Toxicities and Mutagenicities of Platinum Anticancer Drugs Drug Information Journal. 29: 1633S-1644S. DOI: 10.1177/00928615950290S110  0.01
1995 Yarema KJ, Essigmann JM. Evaluation of the Genetic Effects of Defined DNA Lesions Formed by DNA-Damaging Agents Methods. 7: 133-146. DOI: 10.1006/Meth.1995.1020  1
1994 Yarema KJ, Wilson JM, Lippard SJ, Essigmann JM. Effects of DNA adduct structure and distribution on the mutagenicity and genotoxicity of two platinum anticancer drugs. Journal of Molecular Biology. 236: 1034-48. PMID 8120885 DOI: 10.1016/0022-2836(94)90010-8  1
1993 Bradley LJ, Yarema KJ, Lippard SJ, Essigmann JM. Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry. 32: 982-8. PMID 8422401 DOI: 10.1021/Bi00054A031  1
1992 Szymkowski DE, Yarema K, Essigmann JM, Lippard SJ, Wood RD. An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts. Proceedings of the National Academy of Sciences of the United States of America. 89: 10772-6. PMID 1438274 DOI: 10.1073/Pnas.89.22.10772  1
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