Kevin Yarema - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kim C, Shores L, Guo Q, Aly A, Jeon OH, Kim DH, Bernstein N, Bhattacharya R, Chae JJ, Yarema KJ, Elisseeff JH. Electrospun microfiber scaffolds with anti-inflammatory tri-butanoylated N-acetyl-D-glucosamine promote cartilage regeneration. Tissue Engineering. Part A. PMID 27019285 DOI: 10.1089/ten.TEA.2015.0469  0.68
2015 Kim C, Jeon OH, Kim DH, Chae JJ, Shores L, Bernstein N, Bhattacharya R, Coburn JM, Yarema KJ, Elisseeff JH. Local delivery of a carbohydrate analog for reducing arthritic inflammation and rebuilding cartilage. Biomaterials. 83: 93-101. PMID 26773662 DOI: 10.1016/j.biomaterials.2015.12.029  0.68
2015 Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H. Lectin staining and Western blot data showing differential sialylation of nutrient-deprived cancer cells to sialic acid supplementation. Data in Brief. 5: 481-488. PMID 26629491 DOI: 10.1016/j.dib.2015.09.043  0.68
2015 Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H. Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation. Biomaterials. 70: 23-36. PMID 26295436 DOI: 10.1016/j.biomaterials.2015.08.020  0.68
2015 Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H. Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical Proteomics. 12: 11. PMID 25987888 DOI: 10.1186/s12014-015-9083-8  0.68
2015 Saeui CT, Urias E, Liu L, Mathew MP, Yarema KJ. Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications. Glycoconjugate Journal. 32: 425-41. PMID 25931032 DOI: 10.1007/s10719-015-9583-9  0.68
2014 Gibson M, Li H, Coburn J, Moroni L, Nahas Z, Bingham C, Yarema K, Elisseeff J. Intra-articular delivery of glucosamine for treatment of experimental osteoarthritis created by a medial meniscectomy in a rat model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 302-9. PMID 24600703 DOI: 10.1002/jor.22445  0.68
2014 Du J, Tan E, Kim HJ, Zhang A, Bhattacharya R, Yarema KJ. Comparative evaluation of chitosan, cellulose acetate, and polyethersulfone nanofiber scaffolds for neural differentiation. Carbohydrate Polymers. 99: 483-90. PMID 24274534 DOI: 10.1016/j.carbpol.2013.08.050  0.64
2013 Coburn JM, Wo L, Bernstein N, Bhattacharya R, Aich U, Bingham CO, Yarema KJ, Elisseeff JH. Short-chain fatty acid-modified hexosamine for tissue-engineering osteoarthritic cartilage. Tissue Engineering. Part A. 19: 2035-44. PMID 23638885 DOI: 10.1089/ten.TEA.2012.0317  0.32
2013 Coburn JM, Bernstein N, Bhattacharya R, Aich U, Yarema KJ, Elisseeff JH. Differential response of chondrocytes and chondrogenic-induced mesenchymal stem cells to C1-OH tributanoylated N-acetylhexosamines. Plos One. 8: e58899. PMID 23516573 DOI: 10.1371/journal.pone.0058899  0.32
2013 Shah P, Yang S, Sun S, Aiyetan P, Yarema KJ, Zhang H. Mass spectrometric analysis of sialylated glycans with use of solid-phase labeling of sialic acids. Analytical Chemistry. 85: 3606-13. PMID 23445396 DOI: 10.1021/ac3033867  0.68
2013 Bennun SV, Yarema KJ, Betenbaugh MJ, Krambeck FJ. Integration of the transcriptome and glycome for identification of glycan cell signatures. Plos Computational Biology. 9: e1002813. PMID 23326219 DOI: 10.1371/journal.pcbi.1002813  0.68
2012 Mathew MP, Tan E, Shah S, Bhattacharya R, Adam Meledeo M, Huang J, Espinoza FA, Yarema KJ. Extracellular and intracellular esterase processing of SCFA-hexosamine analogs: implications for metabolic glycoengineering and drug delivery. Bioorganic & Medicinal Chemistry Letters. 22: 6929-33. PMID 23041156 DOI: 10.1016/j.bmcl.2012.09.017  0.68
2012 Almaraz RT, Tian Y, Bhattarcharya R, Tan E, Chen SH, Dallas MR, Chen L, Zhang Z, Zhang H, Konstantopoulos K, Yarema KJ. Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis. Molecular & Cellular Proteomics : McP. 11: M112.017558. PMID 22457533 DOI: 10.1074/mcp.M112.017558  0.68
2012 Almaraz RT, Aich U, Khanna HS, Tan E, Bhattacharya R, Shah S, Yarema KJ. Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations. Biotechnology and Bioengineering. 109: 992-1006. PMID 22068462 DOI: 10.1002/bit.24363  0.68
2012 Almaraz RT, Mathew MP, Tan E, Yarema KJ. Metabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation. Annals of Biomedical Engineering. 40: 806-15. PMID 22037949 DOI: 10.1007/s10439-011-0450-y  0.68
2011 Granell AE, Palter KB, Akan I, Aich U, Yarema KJ, Betenbaugh MJ, Thornhill WB, Recio-Pinto E. DmSAS is required for sialic acid biosynthesis in cultured Drosophila third instar larvae CNS neurons. Acs Chemical Biology. 6: 1287-95. PMID 21919466 DOI: 10.1021/cb200238k  0.68
2011 Du J, Che PL, Aich U, Tan E, Kim HJ, Sampathkumar SG, Yarema KJ. Deciphering glycan linkages involved in Jurkat cell interactions with gold-coated nanofibers via sugar-displayed thiols. Bioorganic & Medicinal Chemistry Letters. 21: 4980-4. PMID 21684742 DOI: 10.1016/j.bmcl.2011.05.044  0.68
2011 Du J, Che PL, Wang ZY, Aich U, Yarema KJ. Designing a binding interface for control of cancer cell adhesion via 3D topography and metabolic oligosaccharide engineering. Biomaterials. 32: 5427-37. PMID 21549424 DOI: 10.1016/j.biomaterials.2011.04.005  0.68
2010 Tan E, Almaraz RT, Khanna HS, Du J, Yarema KJ. Experimental Design Considerations for In Vitro Non-Natural Glycan Display via Metabolic Oligosaccharide Engineering. Current Protocols in Chemical Biology. 2: 171-94. PMID 23839968 DOI: 10.1002/9780470559277.ch100059  0.64
2010 Wang Z, Che PL, Du J, Ha B, Yarema KJ. Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drug candidate ZM241385. Plos One. 5: e13883. PMID 21079735 DOI: 10.1371/journal.pone.0013883  0.68
2010 Lim SH, Liu XY, Song H, Yarema KJ, Mao HQ. The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells. Biomaterials. 31: 9031-9. PMID 20797783 DOI: 10.1016/j.biomaterials.2010.08.021  0.68
2010 Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconjugate Journal. 27: 445-59. PMID 20458533 DOI: 10.1007/s10719-010-9292-3  0.68
2010 Du J, Yarema KJ. Carbohydrate engineered cells for regenerative medicine. Advanced Drug Delivery Reviews. 62: 671-82. PMID 20117158 DOI: 10.1016/j.addr.2010.01.003  0.64
2009 Wang Z, Du J, Che PL, Meledeo MA, Yarema KJ. Hexosamine analogs: from metabolic glycoengineering to drug discovery Current Opinion in Chemical Biology. 13: 565-572. PMID 19747874 DOI: 10.1016/j.cbpa.2009.08.001  0.68
2009 Du J, Meledeo MA, Wang Z, Khanna HS, Paruchuri VD, Yarema KJ. Metabolic glycoengineering: sialic acid and beyond. Glycobiology. 19: 1382-401. PMID 19675091 DOI: 10.1093/glycob/cwp115  0.68
2009 Wang Z, Sarje A, Che PL, Yarema KJ. Moderate strength (0.23-0.28 T) static magnetic fields (SMF) modulate signaling and differentiation in human embryonic cells. Bmc Genomics. 10: 356. PMID 19653909 DOI: 10.1186/1471-2164-10-356  0.68
2009 Krambeck FJ, Bennun SV, Narang S, Choi S, Yarema KJ, Betenbaugh MJ. A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data. Glycobiology. 19: 1163-75. PMID 19506293 DOI: 10.1093/glycob/cwp081  0.68
2009 Elmouelhi N, Aich U, Paruchuri VD, Meledeo MA, Campbell CT, Wang JJ, Srinivas R, Khanna HS, Yarema KJ. Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. Journal of Medicinal Chemistry. 52: 2515-30. PMID 19326913 DOI: 10.1021/jm801661m  0.68
2008 Campbell CT, Aich U, Weier CA, Wang JJ, Choi SS, Wen MM, Maisel K, Sampathkumar SG, Yarema KJ. Targeting pro-invasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells. Journal of Medicinal Chemistry. 51: 8135-47. PMID 19053749 DOI: 10.1021/jm800873k  0.68
2008 Kim EJ, Shin HY, Park S, Sung D, Jon S, Sampathkumar SG, Yarema KJ, Choi SY, Kim K. Electrochemically active, anti-biofouling polymer adlayers on indium-tin-oxide electrodes. Chemical Communications (Cambridge, England). 3543-5. PMID 18654707 DOI: 10.1039/b804816a  1
2008 Aich U, Campbell CT, Elmouelhi N, Weier CA, Sampathkumar SG, Choi SS, Yarema KJ. Regioisomeric SCFA attachment to hexosamines separates metabolic flux from cytotoxicity and MUC1 suppression. Acs Chemical Biology. 3: 230-40. PMID 18338853 DOI: 10.1021/cb7002708  0.68
2007 Daubeuf S, Aucher A, Sampathkumar SG, Preville X, Yarema KJ, Hudrisier D. Chemical labels metabolically installed into the glycoconjugates of the target cell surface can be used to track lymphocyte/target cell interplay via trogocytosis: comparisons with lipophilic dyes and biotin. Immunological Investigations. 36: 687-712. PMID 18161525 DOI: 10.1080/08820130701674596  1
2007 Campbell CT, Sampathkumar SG, Yarema KJ. Metabolic oligosaccharide engineering: perspectives, applications, and future directions. Molecular Biosystems. 3: 187-94. PMID 17308665 DOI: 10.1039/b614939c  0.68
2007 Faure C, Chalazonitis A, Rhéaume C, Bouchard G, Sampathkumar SG, Yarema KJ, Gershon MD. Gangliogenesis in the enteric nervous system: roles of the polysialylation of the neural cell adhesion molecule and its regulation by bone morphogenetic protein-4. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 44-59. PMID 16958105 DOI: 10.1002/dvdy.20943  0.68
2006 Sampathkumar SG, Jones MB, Yarema KJ. Metabolic expression of thiol-derivatized sialic acids on the cell surface and their quantitative estimation by flow cytometry. Nature Protocols. 1: 1840-51. PMID 17487167 DOI: 10.1038/nprot.2006.252  1
2006 Sampathkumar SG, Li AV, Yarema KJ. Synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. Nature Protocols. 1: 2377-85. PMID 17406481 DOI: 10.1038/nprot.2006.319  1
2006 Sampathkumar SG, Jones MB, Meledeo MA, Campbell CT, Choi SS, Hida K, Gomutputra P, Sheh A, Gilmartin T, Head SR, Yarema KJ. Targeting glycosylation pathways and the cell cycle: sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. Chemistry & Biology. 13: 1265-75. PMID 17185222 DOI: 10.1016/j.chembiol.2006.09.016  0.68
2006 Sampathkumar SG, Li A, Yarema KJ. Sialic acid and the central nervous system: perspectives on biological functions, detection, imaging methods and manipulation. Cns & Neurological Disorders Drug Targets. 5: 425-40. PMID 16918394  1
2006 Wang Z, Sun Z, Li AV, Yarema KJ. Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation. The Journal of Biological Chemistry. 281: 27016-28. PMID 16847058 DOI: 10.1074/jbc.M604903200  0.64
2006 Sampathkumar SG, Li AV, Jones MB, Sun Z, Yarema KJ. Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology. Nature Chemical Biology. 2: 149-52. PMID 16474386 DOI: 10.1038/nchembio770  1
2005 Yarema KJ, Sun Z. A photochemical snapshot of CD22 binding. Nature Chemical Biology. 1: 69-70. PMID 16408000 DOI: 10.1038/nchembio0705-69  0.36
2005 Campbell CT, Yarema KJ. Large-scale approaches for glycobiology. Genome Biology. 6: 236. PMID 16277754 DOI: 10.1186/gb-2005-6-11-236  0.68
2005 Salama I, Hinderlich S, Shlomai Z, Eisenberg I, Krause S, Yarema K, Argov Z, Lochmuller H, Reutter W, Dabby R, Sadeh M, Ben-Bassat H, Mitrani-Rosenbaum S. No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation. Biochemical and Biophysical Research Communications. 328: 221-6. PMID 15670773 DOI: 10.1016/j.bbrc.2004.12.157  0.68
2005 Sampathkumar SG, Yarema KJ. Targeting cancer cells with dendrimers. Chemistry & Biology. 12: 5-6. PMID 15664507 DOI: 10.1016/j.chembiol.2004.12.007  1
2004 Kim EJ, Jones MB, Rhee JK, Sampathkumar SG, Yarema KJ. Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications. Biotechnology Progress. 20: 1674-82. PMID 15575698 DOI: 10.1021/bp049841q  1
2004 Murrell MP, Yarema KJ, Levchenko A. The systems biology of glycosylation. Chembiochem : a European Journal of Chemical Biology. 5: 1334-47. PMID 15457533 DOI: 10.1002/cbic.200400143  0.68
2004 Hinderlich S, Salama I, Eisenberg I, Potikha T, Mantey LR, Yarema KJ, Horstkorte R, Argov Z, Sadeh M, Reutter W, Mitrani-Rosenbaum S. The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy. Febs Letters. 566: 105-9. PMID 15147877 DOI: 10.1016/j.febslet.2004.04.013  0.68
2004 Kim EJ, Sampathkumar SG, Jones MB, Rhee JK, Baskaran G, Goon S, Yarema KJ. Characterization of the metabolic flux and apoptotic effects of O-hydroxyl- and N-acyl-modified N-acetylmannosamine analogs in Jurkat cells. The Journal of Biological Chemistry. 279: 18342-52. PMID 14966124 DOI: 10.1074/jbc.M400205200  1
2004 Jones MB, Teng H, Rhee JK, Lahar N, Baskaran G, Yarema KJ. Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids. Biotechnology and Bioengineering. 85: 394-405. PMID 14755557 DOI: 10.1002/bit.10901  0.6
2003 Tong L, Baskaran G, Jones MB, Rhee JK, Yarema KJ. Glycosylation changes as markers for the diagnosis and treatment of human disease. Biotechnology & Genetic Engineering Reviews. 20: 199-244. PMID 14997853  0.6
2003 Viswanathan K, Lawrence S, Hinderlich S, Yarema KJ, Lee YC, Betenbaugh MJ. Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them. Biochemistry. 42: 15215-25. PMID 14690432 DOI: 10.1021/bi034994s  0.68
2003 Luchansky SJ, Yarema KJ, Takahashi S, Bertozzi CR. GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism. The Journal of Biological Chemistry. 278: 8035-42. PMID 12499362 DOI: 10.1074/jbc.M212127200  0.68
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