Eric J. Toone - Publications

Affiliations: 
Chemistry Duke University, Durham, NC 
Area:
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
Website:
http://fds.duke.edu/db/aas/Chemistry/faculty/eric.toone

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhao J, Cochrane CS, Najeeb J, Gooden D, Sciandra C, Fan P, Lemaitre N, Newns K, Nicholas RA, Guan Z, Thaden JT, Fowler VG, Spasojevic I, Sebbane F, Toone EJ, et al. Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens. Science Translational Medicine. 15: eadf5668. PMID 37556556 DOI: 10.1126/scitranslmed.adf5668  0.664
2016 Lee CJ, Liang X, Wu Q, Najeeb J, Zhao J, Gopalaswamy R, Titecat M, Sebbane F, Lemaitre N, Toone EJ, Zhou P. Drug design from the cryptic inhibitor envelope. Nature Communications. 7: 10638. PMID 26912110 DOI: 10.1038/Ncomms10638  0.325
2015 King JR, Bowers CM, Toone EJ. Specific binding at the cellulose binding module-cellulose interface observed by force spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 3431-40. PMID 25738531 DOI: 10.1021/La504836U  0.69
2014 Xia W, Gooden D, Liu L, Zhao S, Soderblom EJ, Toone EJ, Beyer WF, Walder H, Spector NL. Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis. Plos One. 9: e88983. PMID 24551203 DOI: 10.1371/Journal.Pone.0088983  0.674
2014 Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC. Acs Chemical Biology. 9: 237-46. PMID 24117400 DOI: 10.1021/Cb400067G  0.323
2014 Sund JB, Causey CP, Wolter SD, Parker CB, Stoner BR, Toone EJ, Glass JT. Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors Applied Surface Science. 301: 293-299. DOI: 10.1016/J.Apsusc.2014.02.067  0.686
2014 Bowers CM, Zhang M, Lyubarskaya Y, Toone EJ, Tang C, Shestopalov AA. Organic Electronics: Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties (Adv. Mater. Interfaces 2/2014) Advanced Materials Interfaces. 1. DOI: 10.1002/Admi.201470012  0.721
2014 Bowers CM, Zhang M, Lyubarskaya Y, Toone EJ, Tang C, Shestopalov AA. Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties Advanced Materials Interfaces. 1. DOI: 10.1002/Admi.201300109  0.74
2013 Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors. Journal of Medicinal Chemistry. 56: 6954-66. PMID 23914798 DOI: 10.1021/Jm4007774  0.322
2013 Bowers CM, Carlson DA, Rivera M, Clark RL, Toone EJ. Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy. The Journal of Physical Chemistry. B. 117: 4755-62. PMID 23537272 DOI: 10.1021/Jp309393S  0.71
2013 Wang Y, King JR, Wu P, Pelzman DL, Beratan DN, Toone EJ. Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril. Journal of the American Chemical Society. 135: 6084-91. PMID 23510488 DOI: 10.1021/Ja311327V  0.31
2013 Sinclair S, Bhattacharyya J, Little D, Bowles R, Gooden D, Toone E, Chilkoti A, Setton L. Pharmacokinetics of a thermally responsive curcumin conjugate for local antagonism of neuroinflammation in disc herniation Osteoarthritis and Cartilage. 21: S292-S293. DOI: 10.1016/J.Joca.2013.02.613  0.649
2012 Wilfong EM, Du Y, Toone EJ. An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1. Bioorganic & Medicinal Chemistry Letters. 22: 6521-4. PMID 22985855 DOI: 10.1016/J.Bmcl.2012.05.032  0.76
2012 Bowers CM, Shestopalov AA, Clark RL, Toone EJ. Multicomponent patterning of indium tin oxide. Acs Applied Materials & Interfaces. 4: 3932-7. PMID 22834789 DOI: 10.1021/Am300768F  0.749
2012 Bowers CM, Carlson DA, Shestopalov AA, Clark RL, Toone EJ. A general and efficient cantilever functionalization technique for AFM molecular recognition studies. Biopolymers. 97: 761-5. PMID 22806495 DOI: 10.1002/Bip.22061  0.778
2012 Cheriyan M, Toone EJ, Fierke CA. Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates. Biochemistry. 51: 1658-68. PMID 22316217 DOI: 10.1021/Bi201899B  0.382
2012 Yamazaki A, Li J, Zeng Q, Khokhani D, Hutchins WC, Yost AC, Biddle E, Toone EJ, Chen X, Yang CH. Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. Antimicrobial Agents and Chemotherapy. 56: 36-43. PMID 21968370 DOI: 10.1128/Aac.00732-11  0.31
2012 Coombs GS, Schmitt AA, Canning CA, Alok A, Low IC, Banerjee N, Kaur S, Utomo V, Jones CM, Pervaiz S, Toone EJ, Virshup DM. Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer. Oncogene. 31: 213-25. PMID 21666721 DOI: 10.1038/Onc.2011.228  0.589
2011 Bowers CM, Toone EJ, Clark RL, Shestopalov AA. Soft lithographic functionalization and patterning oxide-free silicon and germanium. Journal of Visualized Experiments : Jove. PMID 22214997 DOI: 10.3791/3478  0.762
2011 Lund LN, Christensen T, Toone E, Houen G, Staby A, St. Hilaire PM. Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry Journal of Molecular Recognition. 24: 945-952. PMID 22038801 DOI: 10.1002/Jmr.1140  0.332
2011 Cheriyan M, Walters MJ, Kang BD, Anzaldi LL, Toone EJ, Fierke CA. Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate. Bioorganic & Medicinal Chemistry. 19: 6447-53. PMID 21944547 DOI: 10.1016/J.Bmc.2011.08.056  0.577
2011 Wilfong EM, Kogiso Y, Muthukrishnan S, Kowatz T, Du Y, Bowie A, Naismith JH, Hadad CM, Toone EJ, Gustafson TL. A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model. Journal of the American Chemical Society. 133: 11515-23. PMID 21692482 DOI: 10.1021/Ja1098287  0.747
2011 Nguyen BD, Cunningham D, Liang X, Chen X, Toone EJ, Raetz CR, Zhou P, Valdivia RH. Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. Proceedings of the National Academy of Sciences of the United States of America. 108: 10284-9. PMID 21628561 DOI: 10.1073/Pnas.1107478108  0.337
2011 Shestopalov AA, Morris CJ, Vogen BN, Hoertz A, Clark RL, Toone EJ. Soft-lithographic approach to functionalization and nanopatterning oxide-free silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 6478-85. PMID 21520913 DOI: 10.1021/La200373G  0.761
2011 Morris CJ, Shestopalov AA, Gold BH, Clark RL, Toone EJ. Patterning NHS-terminated SAMs on germanium. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 6486-9. PMID 21504221 DOI: 10.1021/La200374K  0.62
2011 Liang X, Lee CJ, Chen X, Chung HS, Zeng D, Raetz CR, Li Y, Zhou P, Toone EJ. Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. Bioorganic & Medicinal Chemistry. 19: 852-60. PMID 21194954 DOI: 10.1016/J.Bmc.2010.12.017  0.35
2011 Lee CJ, Liang X, Chen X, Zeng D, Joo SH, Chung HS, Barb AW, Swanson SM, Nicholas RA, Li Y, Toone EJ, Raetz CR, Zhou P. Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chemistry & Biology. 18: 38-47. PMID 21167751 DOI: 10.1016/J.Chembiol.2010.11.011  0.423
2011 Hwang S, Schmitt AA, Luteran AE, Toone EJ, McCafferty DG. Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST. Biochemistry. 50: 546-57. PMID 21142040 DOI: 10.1021/Bi101776T  0.758
2010 Colomer J, Schmitt AA, Toone EJ, Means AR. Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist. Biochemistry. 49: 4244-54. PMID 20392081 DOI: 10.1021/Bi1001213  0.613
2010 Shestopalov AA, Clark RL, Toone EJ. Catalytic microcontact printing on chemically functionalized H-terminated silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 1449-51. PMID 19950970 DOI: 10.1021/La903465F  0.623
2010 Shestopalov AA, Clark RL, Toone EJ. Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols. Nano Letters. 10: 43-6. PMID 19950928 DOI: 10.1021/Nl902588D  0.61
2010 Wilfong EM, Locklear U, Toone EJ. A single step purification for autolytic zinc proteinases. Bioorganic & Medicinal Chemistry Letters. 20: 280-2. PMID 19942433 DOI: 10.1016/J.Bmcl.2009.10.114  0.715
2010 Rivera M, Morris C, Carlson D, Toone EJ, Cole DG, Clark RL. Minimizing tip-sample contact force in automated atomic force microscope based force spectroscopy Proceedings of the Asme International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, Detc2009. 6: 731-736. DOI: 10.1115/DETC2009-87378  0.409
2009 Arnold JJ, Choksi Y, Chen X, Shimazaki A, Hatten J, Toone EJ, Epstein DL, Challa P. Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 25: 179-86. PMID 19456251 DOI: 10.1089/Jop.2008.0107  0.739
2009 Chakrapani H, Bartberger MD, Toone EJ. C-nitroso donors of nitric oxide. The Journal of Organic Chemistry. 74: 1450-3. PMID 19146387 DOI: 10.1021/Jo802517T  0.606
2008 Walters MJ, Srikannathasan V, McEwan AR, Naismith JH, Fierke CA, Toone EJ. Characterization and crystal structure of Escherichia coli KDPGal aldolase. Bioorganic & Medicinal Chemistry. 16: 710-20. PMID 17981470 DOI: 10.1016/J.Bmc.2007.10.043  0.579
2007 Cheriyan M, Toone EJ, Fierke CA. Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates. Protein Science : a Publication of the Protein Society. 16: 2368-77. PMID 17962400 DOI: 10.1110/Ps.073042907  0.412
2007 Shestopalov AA, Clark RL, Toone EJ. Inkless microcontact printing on self-assembled monolayers of fmoc-protected aminothiols. Journal of the American Chemical Society. 129: 13818-9. PMID 17949005 DOI: 10.1021/Ja076226K  0.597
2007 Snyder PW, Johannes MS, Vogen BN, Clark RL, Toone EJ. Biocatalytic microcontact printing. The Journal of Organic Chemistry. 72: 7459-61. PMID 17705546 DOI: 10.1021/Jo0711541  0.751
2007 Walters MJ, Toone EJ. Pyruvate aldolases in chiral carbon-carbon bond formation. Nature Protocols. 2: 1825-30. PMID 17641651 DOI: 10.1038/Nprot.2007.260  0.533
2007 Snyder PW, Lee G, Marszalek PE, Clark RL, Toone EJ. A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities. Proceedings of the National Academy of Sciences of the United States of America. 104: 2579-84. PMID 17307881 DOI: 10.1073/Pnas.0606604104  0.603
2007 Matsuoka K, Goshu Y, Takezawa Y, Mori T, Sakamoto JI, Yamada A, Onaga T, Koyama T, Hatano K, Snyder PW, Toone EJ, Terunuma D. Practical synthesis of fully protected globotriaose and its glycopolymers Carbohydrate Polymers. 69: 326-335. DOI: 10.1016/J.Carbpol.2006.10.011  0.55
2006 Perry JL, Goldsmith MR, Williams TR, Radack KP, Christensen T, Gorham J, Pasquinelli MA, Toone EJ, Beratan DN, Simon JD. Binding of warfarin influences the acid-base equilibrium of H242 in sudlow site I of human serum albumin. Photochemistry and Photobiology. 82: 1365-9. PMID 16563025 DOI: 10.1562/2006-02-23-Ra-811  0.346
2006 Fullerton SW, Griffiths JS, Merkel AB, Cheriyan M, Wymer NJ, Hutchins MJ, Fierke CA, Toone EJ, Naismith JH. Mechanism of the Class I KDPG aldolase. Bioorganic & Medicinal Chemistry. 14: 3002-10. PMID 16403639 DOI: 10.1016/J.Bmc.2005.12.022  0.789
2006 Lai T, Liu Y, Lee HY, Toone E, Greenberg CS. Human Tissue Transglutaminase Activity Is Inhibited by Protein Kinase Inhibitors: Potential Therapeutic Implication for Hematological Disorders. Blood. 108: 1614-1614. DOI: 10.1182/Blood.V108.11.1614.1614  0.323
2005 Gooden DM, Chakrapani H, Toone EJ. C-nitroso compounds: synthesis, physicochemical properties and biological activities. Current Topics in Medicinal Chemistry. 5: 687-705. PMID 16101429 DOI: 10.2174/1568026054679353  0.76
2005 Zhao YL, McCarren PR, Houk KN, Choi BY, Toone EJ. Nitrosonium-catalyzed decomposition of s-nitrosothiols in solution: a theoretical and experimental study. Journal of the American Chemical Society. 127: 10917-24. PMID 16076198 DOI: 10.1021/Ja050018F  0.482
2005 Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4336-41. PMID 15784746 DOI: 10.1073/Pnas.0408107102  0.698
2005 Pamula VK, Srinivasan V, Chakrapani H, Fair RB, Toone EJ. A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 722-725. DOI: 10.1109/MEMSYS.2005.1454031  0.537
2004 Griffiths JS, Cheriyan M, Corbell JB, Pocivavsek L, Fierke CA, Toone EJ. A bacterial selection for the directed evolution of pyruvate aldolases. Bioorganic & Medicinal Chemistry. 12: 4067-74. PMID 15246084 DOI: 10.1016/J.Bmc.2004.05.034  0.753
2003 Christensen T, Toone EJ. Calorimetric evaluation of protein-carbohydrate affinities. Methods in Enzymology. 362: 486-504. PMID 12968383 DOI: 10.1016/S0076-6879(03)01032-2  0.37
2003 Debenham SD, Snyder PW, Toone EJ. Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands. The Journal of Organic Chemistry. 68: 5805-11. PMID 12868911 DOI: 10.1021/Jo0207271  0.607
2003 Christensen T, Gooden DM, Kung JE, Toone EJ. Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction. Journal of the American Chemical Society. 125: 7357-66. PMID 12797810 DOI: 10.1021/Ja021240C  0.719
2003 Houk KN, Hietbrink BN, Bartberger MD, McCarren PR, Choi BY, Voyksner RD, Stamler JS, Toone EJ. Nitroxyl disulfides, novel intermediates in transnitrosation reactions. Journal of the American Chemical Society. 125: 6972-6. PMID 12783550 DOI: 10.1021/Ja029655L  0.466
2003 Perry JL, Christensen T, Goldsmith MR, Toone EJ, Beratan DN, Simon JD. Binding of ochratoxin A to human serum albumin stabilized by a protein-ligand ion pair Journal of Physical Chemistry B. 107: 7884-7888. DOI: 10.1021/Jp034783X  0.353
2002 Lundquist JJ, Toone EJ. The cluster glycoside effect. Chemical Reviews. 102: 555-78. PMID 11841254 DOI: 10.1021/Cr000418F  0.721
2002 Griffiths JS, Wymer NJ, Njolito E, Niranjanakumari S, Fierke CA, Toone EJ. Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase. Bioorganic & Medicinal Chemistry. 10: 545-50. PMID 11814840 DOI: 10.1016/S0968-0896(01)00307-8  0.781
2002 Lundquist JJ, Kiburz BM, Wu JK, Gibbs KD, Toone EJ. Towards high affinity carbohydrate-binding proteins: Directed evolution of murine galectin-3 Canadian Journal of Chemistry. 80: 999-1009. DOI: 10.1139/V02-086  0.768
2002 Choi BY, Voyksner RD, Toone EJ. Analysis of S-nitrosothiol decomposition Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 799-800.  0.355
2001 Bartberger MD, Mannion JD, Powell SC, Stamler JS, Houk KN, Toone EJ. S-N dissociation energies of S-nitrosothiols: on the origins of nitrosothiol decomposition rates. Journal of the American Chemical Society. 123: 8868-9. PMID 11535101 DOI: 10.1021/Ja0109390  0.706
2001 Wymer N, Buchanan LV, Henderson D, Mehta N, Botting CH, Pocivavsek L, Fierke CA, Toone EJ, Naismith JH. Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure (London, England : 1993). 9: 1-9. PMID 11342129 DOI: 10.1016/S0969-2126(00)00555-4  0.789
2001 DiTusa CA, McCall KA, Christensen T, Mahapatro M, Fierke CA, Toone EJ. Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants. Biochemistry. 40: 5345-51. PMID 11330997 DOI: 10.1021/Bi0017327  0.79
2001 DiTusa CA, Christensen T, McCall KA, Fierke CA, Toone EJ. Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase. Biochemistry. 40: 5338-44. PMID 11330996 DOI: 10.1021/Bi001731E  0.775
2000 Lundquist JJ, Debenham SD, Toone EJ. Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides. The Journal of Organic Chemistry. 65: 8245-50. PMID 11101380 DOI: 10.1021/Jo000943E  0.781
2000 Wymer N, Toone EJ. Enzyme-catalyzed synthesis of carbohydrates. Current Opinion in Chemical Biology. 4: 110-9. PMID 10679369 DOI: 10.1016/S1367-5931(99)00061-7  0.774
2000 Bartberger MD, Houk KN, Powell SC, Mannion JD, Lo KY, Stamler JS, Toone EJ. Theory, spectroscopy, and crystallographic analysis of S-nitrosothiols: Conformational distribution dictates spectroscopic behavior [7] Journal of the American Chemical Society. 122: 5889-5890. DOI: 10.1021/Ja994476Y  0.713
2000 Corbell JB, Lundquist JJ, Toone EJ. A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A Tetrahedron Asymmetry. 11: 95-111. DOI: 10.1016/S0957-4166(99)00589-3  0.753
1999 Buchanan LV, Mehta N, Pocivavsek L, Niranjanakumari S, Toone EJ, Naismith JH. Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 55: 1946-8. PMID 10531504 DOI: 10.1107/S0907444999011166  0.302
1999 Debenham SD, Cossrow J, Toone EJ. Synthesis of α- and β-carbon-linked serine analogues of the P(k) trisaccharide Journal of Organic Chemistry. 64: 9153-9163. DOI: 10.1021/Jo991096M  0.312
1999 Dimick SM, Powell SC, McMahon SA, Moothoo DN, Naismith JH, Toone EJ. On the meaning of affinity: Cluster glycoside effects and concanavalin A Journal of the American Chemical Society. 121: 10286-10296. DOI: 10.1021/Ja991729E  0.644
1998 Cotterill IC, Shelton MC, Machemer DEW, Henderson DP, Toone EJ. Effect of phosphorylation on the reaction rate of unnatural electrophiles with 2-keto-3-deoxy-6-phosphogluconate aldolase Journal of the Chemical Society - Perkin Transactions 1. 1335-1341. DOI: 10.1039/A706764J  0.306
1998 Cotterill IC, Henderson DP, Shelton MC, Toone EJ. The synthetic utility of KDPGal aldolase Journal of Molecular Catalysis - B Enzymatic. 5: 103-111. DOI: 10.1016/S1381-1177(98)00087-3  0.301
1996 Chervenak MC, Toone EJ. Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides. Bioorganic & Medicinal Chemistry. 4: 1963-77. PMID 9007280 DOI: 10.1016/S0968-0896(96)00178-2  0.364
1996 Gupta D, Oscarson S, Raju TS, Stanley P, Toone EJ, Brewer CF. A comparison of the fine saccharide-binding specificity of Dioclea grandiflora lectin and concanavalin A. European Journal of Biochemistry / Febs. 242: 320-6. PMID 8973650 DOI: 10.1111/J.1432-1033.1996.0320R.X  0.327
1996 Clark C, Bast D, Sharp AM, St Hilaire PM, Agha R, Stein PE, Toone EJ, Read RJ, Brunton JL. Phenylalanine 30 plays an important role in receptor binding of verotoxin-1. Molecular Microbiology. 19: 891-9. PMID 8820657 DOI: 10.1046/J.1365-2958.1996.427962.X  0.338
1996 Weatherman RV, Mortell KH, Chervenak M, Kiessling LL, Toone EJ. Specificity of C-glycoside complexation by mannose/glucose specific lectins. Biochemistry. 35: 3619-24. PMID 8639514 DOI: 10.1021/Bi951916Z  0.356
1996 Shelton MC, Cotterill IC, Novak STA, Poonawala RM, Sudarshan S, Toone EJ. 2-keto-3-deoxy-6-phosphogluconate aldolases as catalysts for stereocontrolled carbon-carbon bond formation Journal of the American Chemical Society. 118: X-2125. DOI: 10.1021/Ja952596+  0.353
1995 Chervenak MC, Toone EJ. Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities. Biochemistry. 34: 5685-95. PMID 7727428 DOI: 10.1021/Bi00016A045  0.361
1995 Isbister BD, St. Hilaire PM, Toone EJ. Spatial organization versus total surface area as a predictor of protein hydrophobicity. The hydrophobicity of the concanavalin A binding site Journal of the American Chemical Society. 117: 12877-12878. DOI: 10.1021/Ja00156A033  0.317
1995 Chervenak MC, Toone EJ. Calorimetric Analysis of the Binding of Lectins with Overlapping Carbohydrate-Binding Ligand Specificities. [Erratum to document cited in CA122:259064] Biochemistry. 34: 7966-7966. DOI: 10.1021/Bi00024A022  0.327
1994 St Hilaire PM, Boyd MK, Toone EJ. Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor. Biochemistry. 33: 14452-63. PMID 7981205 DOI: 10.1021/Bi00252A011  0.359
1994 Chervenak MC, Toone EJ. A Direct Measure of the Contribution of Solvent Reorganization to the Enthalpy of Binding Journal of the American Chemical Society. 116: 10533-10539. DOI: 10.1021/Ja00102A021  0.308
1993 Williams BA, Toone EJ. Calorimetric evaluation of enzyme kinetic parameters Journal of Organic Chemistry. 58: 3507-3510. DOI: 10.1021/Jo00065A010  0.321
1991 Toone EJ, Simon ES, Whitesides GM. Enzymic synthesis of uridine 5'-diphosphoglucuronic acid on a gram scale Journal of Organic Chemistry. 56: 5603-5606. DOI: 10.1021/Jo00019A026  0.4
1991 Toone EJ, Jones JB. Enzymes in organic synthesis 50. Probing the dimensions of the large hydrophobic binding region of the active site of pig liver esterase using substituted aryl malonate substrates Tetrahedron: Asymmetry. 2: 1041-1052. DOI: 10.1016/S0957-4166(00)86155-8  0.565
1991 Toone EJ, Jones JB. Enzymes in organic synthesis 49. Resolutions of racemic monocyclic esters with pig liver esterase Tetrahedron: Asymmetry. 2: 207-222. DOI: 10.1016/S0957-4166(00)82360-5  0.51
1990 von der Osten CH, Gioannetti C, Barbas C, Pederson RL, Wang YF, Wong CH, Ozaki A, Toone E, Whitesides GM, Sinskey AJ. Molecular cloning of aldolases for synthetic applications. Annals of the New York Academy of Sciences. 613: 771-5. PMID 2076016 DOI: 10.1111/J.1749-6632.1990.Tb18262.X  0.481
1990 Ozaki A, Toone EJ, Osten CHVd, Sinskey AJ, Whitesides GM. Overproduction and substrate specificity of a bacterial fuculose-1-phosphate aldolase: a new enzymic catalyst for stereocontrolled aldol condensation Journal of the American Chemical Society. 112: 4970-4971. DOI: 10.1021/Ja00168A058  0.432
1990 Toone EJ, Werth MJ, Jones JB. Enzymes in organic synthesis. 47. Active-site model for interpreting and predicting the specificity of pig liver esterase Journal of the American Chemical Society. 112: 4946-4952. DOI: 10.1021/Ja00168A047  0.501
1989 Simon ES, Toone EJ, Ostroff G, Bednarski MD, Whitesides GM. Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. Methods in Enzymology. 179: 275-87. PMID 2560122 DOI: 10.1016/0076-6879(89)79129-1  0.625
1989 Toone EJ, Simon ES, Bednarski MD, Whitesides GM. Enzyme-catalyzed synthesis of carbohydrates Tetrahedron. 45: 5365-5422. DOI: 10.1016/S0040-4020(01)89487-4  0.649
1988 Lam LKP, Brown CM, De Jeso B, Lym L, Toone EJ, Jones JB. Enzymes in organic synthesis. 42. Investigation of the effects of the isozymal composition of pig liver esterase on its stereoselectivity in preparative-scale ester hydrolysis of asymmetric synthetic value Journal of the American Chemical Society. 110: 4409-4411. DOI: 10.1021/Ja00221A049  0.489
1987 Toone EJ, Jones JB. Enzymes in organic synthesis. 40. Evaluation of the enantioselectivity of the pig liver esterase catalyzed hydrolyses of racemic piperidine carboxylic acid esters Canadian Journal of Chemistry. 65: 2722-2726. DOI: 10.1139/V87-452  0.487
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