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David A. Williams, MD - Publications

Affiliations: 
Boston Children's Hospital, Harvard Boston Children's Hospital, Harvard 
Website:
http://www.williamslaboratory.org/david-a-williams-md.html
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Year Citation  Score
2020 Zhu J, Eichler F, Biffi A, Duncan CN, Williams DA, Majzoub JA. The Changing Face of Adrenoleukodystrophy. Endocrine Reviews. PMID 32364223 DOI: 10.1210/Endrev/Bnaa013  0.304
2020 Brendel C, Negre O, Rothe M, Guda S, Parsons G, Harris C, McGuinness M, Abriss D, Tsytsykova A, Klatt D, Bentler M, Pellin D, Christiansen L, Schambach A, Manis J, ... ... Williams DA, et al. Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy. Molecular Therapy. Methods & Clinical Development. 17: 589-600. PMID 32300607 DOI: 10.1016/J.Omtm.2020.03.015  0.351
2020 Kohn DB, Booth C, Kang EM, Pai SY, Shaw KL, Santilli G, Armant M, Buckland KF, Choi U, De Ravin SS, Dorsey MJ, Kuo CY, Leon-Rico D, Rivat C, Izotova N, ... ... Williams DA, et al. Lentiviral gene therapy for X-linked chronic granulomatous disease. Nature Medicine. PMID 31988463 DOI: 10.1038/S41591-019-0735-5  0.338
2020 Walters MC, Locatelli F, Thrasher AJ, Tisdale JF, Orchard PJ, Duncan CN, Kühl J, De Oliveira SN, Sauer MG, Kulozik AE, Yannaki E, Hongeng S, Mapara MY, Krishnamurti L, Hermine O, ... ... Williams DA, et al. Safety of Autologous Hematopoietic Stem Cell Transplantation with Gene Addition Therapy for Transfusion-Dependent β-Thalassemia, Sickle Cell Disease, and Cerebral Adrenoleukodystrophy Biology of Blood and Marrow Transplantation. 26: S38-S39. DOI: 10.1016/J.Bbmt.2019.12.104  0.34
2020 Orchard PJ, Eichler F, Duncan C, De Oliveira S, Thrasher AJ, Kühl J, Lund TC, Sevin C, Gissen P, Amartino H, Smith NJ, Shamir E, Chin W, McNeil E, Aubourg P, ... Williams DA, et al. Lenti-D Hematopoietic Stem Cell Gene Therapy Stabilizes Neurologic Function in Boys with Cerebral Adrenoleukodystrophy Biology of Blood and Marrow Transplantation. 26: S37-S38. DOI: 10.1016/J.Bbmt.2019.12.103  0.307
2019 Curran KJ, Margossian S, Kernan NA, Silverman LB, Williams DA, Shukla NN, Kobos R, Forlenza C, Steinherz P, Prockop S, Boulad F, Spitzer B, Cancio MI, Boelens JJ, Kung AL, et al. Toxicity and Response following CD19-specific CAR T cells in pediatric/young adult relapsed/refractory B-ALL. Blood. PMID 31650176 DOI: 10.1182/Blood.2019001641  0.496
2019 Hu T, Chong Y, Lu S, McGuinness M, Williams DA, Cowell JK. RAC1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome. Haematologica. PMID 31221776 DOI: 10.3324/Haematol.2018.208058  0.3
2019 Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, ... Williams DA, et al. Highly efficient therapeutic gene editing of human hematopoietic stem cells. Nature Medicine. PMID 30911135 DOI: 10.1038/S41591-019-0401-Y  0.348
2019 Esrick EB, Achebe M, Armant M, Bartolucci P, Ciuculescu MF, Daley H, Dansereau C, Di Caprio G, Goncalves B, Hebert N, Heeney MM, Higgins JM, Lehmann LE, Manis JP, Negre O, ... ... Williams DA, et al. Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing Blood. 134: LBA-5-LBA-5. DOI: 10.1182/Blood-2019-132745  0.326
2019 Labrosse R, Chu J, Armant M, Spek Jvd, Miggelbrink A, Fong J, Everett JK, Raymond H, Kessler L, Dansereau C, Mackinnon B, Koo S, Morris E, London WB, Ozen A, ... ... Williams DA, et al. Outcome of Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome Blood. 134: 4629-4629. DOI: 10.1182/Blood-2019-126161  0.307
2019 Duncan C, Eichler F, Thrasher AJ, Orchard PJ, De Oliveira SN, Lund TC, Amartino H, Smith NJ, McNeil E, Chin W, Aubourg P, Williams DA. Updated Safety and Efficacy Outcomes from an Ongoing Phase 2/3 Trial of Lenti-D Autologous Hematopoietic Stem Cell Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy Biology of Blood and Marrow Transplantation. 25: S89-S90. DOI: 10.1016/J.Bbmt.2018.12.169  0.319
2018 Esrick EB, Manis JP, Daley H, Baricordi C, Trébéden-Negre H, Pierciey FJ, Armant M, Nikiforow S, Heeney MM, London WB, Biasco L, Asmal M, Williams DA, Biffi A. Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients. Blood Advances. 2: 2505-2512. PMID 30282642 DOI: 10.1182/Bloodadvances.2018016725  0.335
2018 Clarke EL, Connell AJ, Six E, Kadry NA, Abbas AA, Hwang Y, Everett JK, Hofstaedter CE, Marsh R, Armant M, Kelsen J, Notarangelo LD, Collman RG, Hacein-Bey-Abina S, Kohn DB, ... ... Williams DA, et al. T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency. Genome Medicine. 10: 70. PMID 30261899 DOI: 10.1186/S13073-018-0580-Z  0.309
2018 Zeng J, Bauer DE, Wu Y, Roscoe BP, Liu P, Yao Q, Lazzarrotto C, Clement MK, Cole MA, Luk K, Baricordi C, Esrick EB, Manis JP, Dorfma D, Williams DA, et al. Highly Efficient Therapeutic Gene Editing of BCL11A enhancer in Human Hematopoietic Stem Cells from ß-Hemoglobinopathy Patients for Fetal Hemoglobin Induction Blood. 132: 3482-3482. DOI: 10.1182/Blood-2018-99-119365  0.333
2018 Esrick EB, Brendel C, Manis JP, Armant MA, Negre H, Dansereau C, Ciuculescu MF, Patriarca S, Mackinnon B, Daley H, Richard S, Abriss D, Maxwell R, Braunewell S, Christiansen L, ... ... Williams DA, et al. Flipping the Switch: Initial Results of Genetic Targeting of the Fetal to Adult Globin Switch in Sickle Cell Patients Blood. 132: 1023-1023. DOI: 10.1182/Blood-2018-99-116733  0.358
2018 McCabe A, Brendel C, Frei S, Klatt D, Bentler M, Snapper S, Williams DA. Interleukin-10 Signaling in Hematopoietic Stem and Progenitor Cells Maintains Stem Cell Function and Regulates Inflammation-Induced Myeloid Cell Output Blood. 132: 2407-2407. DOI: 10.1182/Blood-2018-99-116168  0.325
2018 Renella R, Gagne K, Beauchamp E, Schlaeger T, Hofmann I, Shimamura A, Fogel J, Agarwal S, Ebert BL, Markianos K, Springer TA, Fleming MD, Williams DA. Congenital X-Linked Myelodysplasia with Tetraploidy Is Associated with De Novo Germline C-Terminal Mutation of SEPT6, a Septin Filament Protein Blood. 132: 644-644. DOI: 10.1182/Blood-2018-99-114682  0.336
2018 Duncan C, Eichler F, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant MA, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, ... ... Williams DA, et al. Lenti-D Hematopoietic Stem Cell Gene Therapy to Arrest Progression of Cerebral Adrenoleukodystrophy: Interim Results of an International Phase 2/3 Trial Biology of Blood and Marrow Transplantation. 24: S73-S74. DOI: 10.1016/J.Bbmt.2017.12.642  0.3
2017 Eichler F, Duncan C, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant M, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, ... ... Williams DA, et al. Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy. The New England Journal of Medicine. PMID 28976817 DOI: 10.1056/Nejmoa1700554  0.334
2017 Alonso-Ferrero ME, van Til NP, Bartolovic K, Mata MF, Wagemaker G, Moulding D, Williams DA, Kinnon C, Waddington SN, Milsom MD, Howe SJ. Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors. Experimental Hematology. PMID 28911908 DOI: 10.1016/J.Exphem.2017.09.003  0.349
2017 Thrasher AJ, Williams DA. Evolving Gene Therapy in Primary Immunodeficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 1132-1141. PMID 28366768 DOI: 10.1016/J.Ymthe.2017.03.018  0.323
2016 Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim YJ, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype. The Journal of Clinical Investigation. 126: 3868-3878. PMID 27599293 DOI: 10.1172/Jci87885  0.354
2016 Mino A, Troeger A, Brendel C, Cantor A, Harris C, Ciuculescu MF, Williams DA. RhoH participates in a multi-protein complex with the zinc finger protein kaiso that regulates both cytoskeletal structures and chemokine-induced T cells. Small Gtpases. 1-14. PMID 27574848 DOI: 10.1080/21541248.2016.1220780  0.308
2016 Altrock PM, Brendel C, Renella R, Orkin SH, Williams DA, Michor F. Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease. American Journal of Hematology. 91: 931-7. PMID 27299299 DOI: 10.1002/Ajh.24449  0.345
2016 Poletti V, Charrier S, Martin S, Gjata B, Vignaud A, Zhang F, Buckland K, Rothe M, Schambach A, Pai S, Williams DA, Gaspar HB, Thrasher AJ, Mavilio F. Preclinical Development of Gene Therapy for X-Linked Severe Combined Immunodeficiency (SCID-X1) Blood. 128: 4705-4705. DOI: 10.1182/Blood.V128.22.4705.4705  0.371
2016 De Vita S, Li Y, Harris CE, McGuinness M, Williams DA. Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation Blood. 128: 2149-2149. DOI: 10.1182/Blood.V128.22.2149.2149  0.341
2016 Altrock PM, Brendel C, Renella R, Orkin SH, Williams DA, Michor F. 314. Mathematical Modeling of Erythrocyte Chimerism Informs Clinical Strategies for Sickle Cell Disease Molecular Therapy. 24: S126-S127. DOI: 10.1016/S1525-0016(16)33123-9  0.338
2016 Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim Y, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. 282. Circumventing Hematopoietic Toxicities and Reversing Sickle Phenotype by Lineage-Specific BCL11A Knock Down and γ-Globin Induction Molecular Therapy. 24: S113. DOI: 10.1016/S1525-0016(16)33091-X  0.37
2015 Ciuculescu MF, Park SY, Canty K, Mathieu R, Silberstein LE, Williams DA. Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo. Blood. 125: 3105-13. PMID 25824687 DOI: 10.1182/Blood-2014-10-604892  0.367
2015 Walter D, Lier A, Geiselhart A, Thalheimer FB, Huntscha S, Sobotta MC, Moehrle B, Brocks D, Bayindir I, Kaschutnig P, Muedder K, Klein C, Jauch A, Schroeder T, Geiger H, ... ... Williams DA, et al. Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature. 520: 549-52. PMID 25707806 DOI: 10.1038/Nature14131  0.345
2015 Forester CM, Sartain SE, Guo D, Harris MH, Weinberg OK, Fleming MD, London WB, Williams DA, Hofmann I. Pediatric aplastic anemia and refractory cytopenia: A retrospective analysis assessing outcomes and histomorphologic predictors. American Journal of Hematology. 90: 320-6. PMID 25580823 DOI: 10.1002/Ajh.23937  0.308
2015 Zhang MY, Keel SB, Walsh T, Lee MK, Gulsuner S, Watts AC, Pritchard CC, Salipante SJ, Jeng MR, Hofmann I, Williams DA, Fleming MD, Abkowitz JL, King MC, Shimamura A. Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity. Haematologica. 100: 42-8. PMID 25239263 DOI: 10.3324/Haematol.2014.113456  0.329
2015 Chu JI, Henderson LA, Armant M, Male F, Dansereau CH, MacKinnon B, Burke CJ, Cavanaugh ME, London WB, Barlan IB, Özen A, Baris S, Karakoc-Aydiner E, Kiykim A, Hanson IC, ... ... Williams DA, et al. Gene Therapy Using a Self-Inactivating Lentiviral Vector Improves Clinical and Laboratory Manifestations of Wiskott-Aldrich Syndrome Blood. 126: 260-260. DOI: 10.1182/Blood.V126.23.260.260  0.361
2014 Bruedigam C, Bagger FO, Heidel FH, Paine Kuhn C, Guignes S, Song A, Austin R, Vu T, Lee E, Riyat S, Moore AS, Lock RB, Bullinger L, Hill GR, Armstrong SA, ... Williams DA, et al. Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell. 15: 775-90. PMID 25479751 DOI: 10.1016/J.Stem.2014.11.010  0.336
2014 Lane SW, Williams DA, Watt FM. Modulating the stem cell niche for tissue regeneration. Nature Biotechnology. 32: 795-803. PMID 25093887 DOI: 10.1038/Nbt.2978  0.337
2014 Ciuculescu MF, Brendel C, Harris CE, Williams DA. Retroviral transduction of murine and human hematopoietic progenitors and stem cells. Methods in Molecular Biology (Clifton, N.J.). 1185: 287-309. PMID 25062637 DOI: 10.1007/978-1-4939-1133-2_20  0.397
2014 Gordon PM, Dias S, Williams DA. Cytokines secreted by bone marrow stromal cells protect c-KIT mutant AML cells from c-KIT inhibitor-induced apoptosis. Leukemia. 28: 2257-60. PMID 25030047 DOI: 10.1038/Leu.2014.212  0.327
2014 De Vita S, Schneider RK, Garcia M, Wood J, Gavillet M, Ebert BL, Gerbaulet A, Roers A, Levine RL, Mullally A, Williams DA. Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis. Plos One. 9: e96209. PMID 24788138 DOI: 10.1371/Journal.Pone.0096209  0.32
2014 Williams DA, Thrasher AJ. Concise review: lessons learned from clinical trials of gene therapy in monogenic immunodeficiency diseases. Stem Cells Translational Medicine. 3: 636-42. PMID 24682287 DOI: 10.5966/Sctm.2013-0206  0.3
2014 Rose SR, Kim MO, Korbee L, Wilson KA, Ris MD, Eyal O, Sherafat-Kazemzadeh R, Bollepalli S, Harris R, Jeng MR, Williams DA, Smith FO. Oxandrolone for the treatment of bone marrow failure in Fanconi anemia. Pediatric Blood & Cancer. 61: 11-9. PMID 24019220 DOI: 10.1002/Pbc.24617  0.332
2014 Troeger A, Wood J, Williams DA. Investigation of T Cell Subsets and Germinal Center Reaction in a B Cell Malignancy Model of Mice Deficient in the Lymphoma Hyermutable Gene Rhoh Blood. 124: 3294-3294. DOI: 10.1182/Blood.V124.21.3294.3294  0.336
2014 Geiselhart A, Walter D, Lier A, Thalheimer FB, Huntscha S, Brocks D, Bayindir I, Kaschutnig P, Müdder K, Sobotta M, Dick T, Holland-Letz T, Schmezer P, Schröder T, Lane SW, ... ... Williams DA, et al. Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition Blood. 124: 255-255. DOI: 10.1182/Blood.V124.21.255.255  0.303
2013 Williams DA. Broadening the indications for hematopoietic stem cell genetic therapies. Cell Stem Cell. 13: 263-4. PMID 24012366 DOI: 10.1016/J.Stem.2013.08.006  0.322
2013 Pannucci NL, Li D, Sahay S, Thomas EK, Chen R, Tala I, Hu T, Ciccarelli BT, Megjugorac NJ, Adams Iii HC, Rodriguez PL, Fitzpatrick ER, Lagunoff D, Williams DA, Whitehead IP. Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity. Blood Cancer Journal. 3: e135. PMID 23955590 DOI: 10.1038/Bcj.2013.36  0.328
2013 Mullally A, Bruedigam C, Poveromo L, Heidel FH, Purdon A, Vu T, Austin R, Heckl D, Breyfogle LJ, Kuhn CP, Kalaitzidis D, Armstrong SA, Williams DA, Hill GR, Ebert BL, et al. Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera. Blood. 121: 3692-702. PMID 23487027 DOI: 10.1182/Blood-2012-05-432989  0.354
2013 Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA. The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment. Blood. 121: 2474-82. PMID 23335370 DOI: 10.1182/Blood-2012-10-460709  0.346
2013 Walter D, Lier A, Geiselhart A, Huntscha S, Brocks D, Bayindir I, Kaschutnig P, Schmezer P, Lane SW, Essers M, Williams DA, Trumpp A, Milsom MD. HSC Exit From Dormancy Provokes De Novo DNA Damage, Leading To Bone Marrow Failure If Unresolved By The Fanconi Anemia Pathway Blood. 122: 799-799. DOI: 10.1182/Blood.V122.21.799.799  0.318
2013 Hacein-Bey-Abina S, Bushman F, Armant M, Blanche S, Blondeau J, Caccavelli L, Daley H, Dansereau C, deOliveira S, Guo D, Hopkins G, Lim A, Sci M, London WB, Malani N, ... ... Williams DA, et al. Immune Reconstitution and Preliminary Safety Analysis Of 9 Patients Treated With Somatic Gene Therapy For X-Linked Severe Combined Immunodeficiency (SCID-X1) With a Self-Inactivating Gammaretroviral Vector Blood. 122: 715-715. DOI: 10.1182/Blood.V122.21.715.715  0.353
2013 Bruedigam C, Bagger FO, Kuhn CP, Vu T, Austin R, Heidel FH, Bullinger L, Hill GR, Armstrong SA, Williams DA, Lane SW. Inhibition Of Telomerase Is a Novel and Effective Therapy In MLL-Rearranged Acute Myeloid Leukemia (AML) Blood. 122: 2887-2887. DOI: 10.1182/Blood.V122.21.2887.2887  0.348
2013 Reddy PN, Wood J, Harris CE, Xu K, McGuinness M, Radu M, Kosoff R, Chernoff J, Williams DA. Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo Blood. 122: 2419-2419. DOI: 10.1182/Blood.V122.21.2419.2419  0.316
2012 Crequer A, Troeger A, Patin E, Ma CS, Picard C, Pedergnana V, Fieschi C, Lim A, Abhyankar A, Gineau L, Mueller-Fleckenstein I, Schmidt M, Taieb A, Krueger J, Abel L, ... ... Williams DA, et al. Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections. The Journal of Clinical Investigation. 122: 3239-47. PMID 22850876 DOI: 10.1172/Jci62949  0.301
2012 Müller LU, Schlaeger TM, DeVine AL, Williams DA. Induced pluripotent stem cells as a tool for gaining new insights into Fanconi anemia. Cell Cycle (Georgetown, Tex.). 11: 2985-90. PMID 22825249 DOI: 10.4161/Cc.21109  0.342
2012 van der Loo JC, Swaney WP, Grassman E, Terwilliger A, Higashimoto T, Schambach A, Hacein-Bey-Abina S, Nordling DL, Cavazzana-Calvo M, Thrasher AJ, Williams DA, Reeves L, Malik P. Critical variables affecting clinical-grade production of the self-inactivating gamma-retroviral vector for the treatment of X-linked severe combined immunodeficiency. Gene Therapy. 19: 872-6. PMID 22551777 DOI: 10.1038/Gt.2012.37  0.317
2012 Troeger A, Johnson AJ, Wood J, Blum WG, Andritsos LA, Byrd JC, Williams DA. RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans. Blood. 119: 4708-18. PMID 22474251 DOI: 10.1182/Blood-2011-12-395939  0.344
2012 Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, ... ... Williams DA, et al. Overcoming reprogramming resistance of Fanconi anemia cells. Blood. 119: 5449-57. PMID 22371882 DOI: 10.1182/Blood-2012-02-408674  0.356
2012 Lane SW, De Vita S, Alexander KA, Karaman R, Milsom MD, Dorrance AM, Purdon A, Louis L, Bouxsein ML, Williams DA. Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood. 119: 736-44. PMID 22123845 DOI: 10.1182/Blood-2011-07-368753  0.358
2012 Renella R, Perlov A, Harris CE, Bauer DE, Xu J, Guda S, Milsom MD, Orkin SH, Williams DA. Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial Blood. 120: 753-753. DOI: 10.1182/Blood.V120.21.753.753  0.338
2012 De Vita S, Harris CE, Renella R, Mathieu R, McGuinness M, Williams DA. Vav1 Deficiency Differentially Affects Engraftment of Fetal Hematopoietic Organs During Development Compared with Adult Marrow After Transplantation Blood. 120: 1212-1212. DOI: 10.1182/Blood.V120.21.1212.1212  0.334
2011 Croke M, Ross FP, Korhonen M, Williams DA, Zou W, Teitelbaum SL. Rac deletion in osteoclasts causes severe osteopetrosis. Journal of Cell Science. 124: 3811-21. PMID 22114304 DOI: 10.1242/Jcs.086280  0.314
2011 Mondal S, Ghosh-Roy S, Loison F, Li Y, Jia Y, Harris C, Williams DA, Luo HR. PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase. Journal of Immunology (Baltimore, Md. : 1950). 187: 5783-94. PMID 22043008 DOI: 10.4049/Jimmunol.1100484  0.302
2011 Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Differential niche and Wnt requirements during acute myeloid leukemia progression Blood. 118: 2849-2856. PMID 21765021 DOI: 10.1182/Blood-2011-03-345165  0.328
2011 Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA. Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 9607-12. PMID 21606370 DOI: 10.1073/Pnas.1102018108  0.355
2011 Tolar J, Adair JE, Antoniou M, Bartholomae CC, Becker PS, Blazar BR, Bueren J, Carroll T, Cavazzana-Calvo M, Clapp DW, Dalgleish R, Galy A, Gaspar HB, Hanenberg H, Von Kalle C, ... ... Williams DA, et al. Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1193-8. PMID 21540837 DOI: 10.1038/Mt.2011.78  0.33
2011 Dorrance AM, Kosoff R, McGuinness M, Harris C, De Vita S, Mathieu R, Lane SW, Milsom MD, Chernoff J, Williams DA. Pak A Proteins Are Essential for Hematopoietic Stem/Progenitor Cell (HSC/P) Engraftment Through Regulation of Signaling Pathways Controlling HSC/P Proliferation, Survival, Migration, and the Actin Cytoskeleton Blood. 118: 917-917. DOI: 10.1182/Blood.V118.21.917.917  0.343
2011 Mueller L, Milsom MD, Harris C, Vyas R, Brumme K, Parmar K, Schambach A, Grassman E, Park I, Wendy L, Strait K, Schlaeger T, Devine AL, D'Andrea AD, Daley GQ, ... Williams DA, et al. Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo Blood. 118: 672-672. DOI: 10.1182/Blood.V118.21.672.672  0.358
2011 Troeger A, Chae H, Wood J, Williams DA. Functional Characterization of the RhoH c-Terminus and Insert Domain As Potential Drug Targets Blood. 118: 1781-1781. DOI: 10.1182/Blood.V118.21.1781.1781  0.314
2011 Pai S, Notarangelo LD, Harris C, Cattaneo F, Wladkowski M, Armant M, Kao GS, Wielgosz M, Nienhuis AW, Modlich U, Brugman M, Schambach A, Rothe M, Thornhill SI, Gaspar HB, ... ... Williams DA, et al. Somatic Gene Therapy for X-Linked Severe Combined Immunodeficiency Using a Self-Inactivating Modified Gammaretroviral Vector Results in An Improved Preclinical Safety Profile and Early Clinical Efficacy in a Human Patient Blood. 118: 164-164. DOI: 10.1182/Blood.V118.21.164.164  0.375
2011 Mizukawa B, Shrestha M, Wunderlich M, Chou F, Griesinger A, Kumar A, Zheng Y, Williams DA, Mulloy JC. Rac GTPase Survival Signaling Through Anti-Apoptotic Bcl-2 Proteins Reveals a Target for Combination Therapy in MLL-AF9 Acute Myeloid Leukemia Blood. 118: 1536-1536. DOI: 10.1182/Blood.V118.21.1536.1536  0.343
2010 Williams DA, Keating A. Enhancing research in regenerative medicine. Blood. 116: 866-7. PMID 20705767 DOI: 10.1182/Blood-2010-05-282723  0.31
2010 Milsom MD, Williams DA. Gaining the hard yard: pre-clinical evaluation of lentiviral-mediated gene therapy for the treatment of beta-thalassemia. Embo Molecular Medicine. 2: 291-3. PMID 20677209 DOI: 10.1002/Emmm.201000086  0.333
2010 Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas JA. Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo. Blood. 116: 81-4. PMID 20407032 DOI: 10.1182/Blood-2009-10-247437  0.331
2010 Lane SW, Sykes SM, Al-Shahrour F, Shterental S, Paktinat M, Lo Celso C, Jesneck JL, Ebert BL, Williams DA, Gilliland DG. The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood. 115: 3489-97. PMID 20197553 DOI: 10.1182/Blood-2009-11-251728  0.334
2010 Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y. Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen. Haematologica. 95: 27-35. PMID 20065081 DOI: 10.3324/Haematol.2009.006239  0.318
2010 Sanchez-Aguilera A, Rattmann I, Drew DZ, Müller LU, Summey V, Lucas DM, Byrd JC, Croce CM, Gu Y, Cancelas JA, Johnston P, Moritz T, Williams DA. Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia. Leukemia. 24: 97-104. PMID 19847197 DOI: 10.1038/Leu.2009.217  0.333
2010 Xu J, Szczur K, Xu H, Geiger H, Zheng Y, Srour E, Williams DA, Filippi M. Rho GTPase Activating Protein p190-B Regulates Hematopoietic Stem Cell Fate Decision Blood. 116: 575-575. DOI: 10.1182/Blood.V116.21.575.575  0.326
2010 Sanchez-Aguilera A, Lee Y, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Adrienne D, Luo HR, Scadden DT, Williams DA. Vav1 Regulates Perivascular Homing, Bone Marrow Retention and Engraftment of Hematopoietic Stem Cells Via SDF1a Signaling Blood. 116: 400-400. DOI: 10.1182/Blood.V116.21.400.400  0.357
2010 Troeger A, Johann P, Senturk M, Milsom MD, Williams DA. Intact Rac Signaling Is Important for Leukemia Cell Survival Blood. 116: 2885-2885. DOI: 10.1182/Blood.V116.21.2885.2885  0.327
2010 Dorrance AM, Sanchez-Aguilera A, Vita SD, Milsom MD, Chernoff J, Williams DA. Group A Pak Proteins Are Essential for HSC/P Engraftment. Blood. 116: 2624-2624. DOI: 10.1182/Blood.V116.21.2624.2624  0.35
2010 Mueller L, Milsom MD, Brumme K, Harris C, Parmar K, Zhu K, Wendy L, Strait K, D'Andrea AD, Daley GQ, Williams DA. Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway Blood. 116: 196-196. DOI: 10.1182/Blood.V116.21.196.196  0.347
2010 Lane SW, Sykes SM, Ferraro F, Lin CP, Gilliland DG, Williams DA, Scadden DT, Celso CL. Leukemia stem cells occupy niches that are physically distinct and independent of the normal constraints that apply to hematopoietic stem cells Experimental Hematology. 38. DOI: 10.1016/J.Exphem.2010.07.008  0.307
2009 Williams DA. Correction and apology Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1660. PMID 19789558 DOI: 10.1038/Mt.2009.212  0.302
2009 Xu H, Eleswarapu S, Geiger H, Szczur K, Daria D, Zheng Y, Settleman J, Srour EF, Williams DA, Filippi MD. Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential. Blood. 114: 3557-66. PMID 19713466 DOI: 10.1182/Blood-2009-02-205815  0.316
2009 Williams DA. Gene therapy continues to mature and to face challenges Molecular Therapy. 17: 1305-1306. PMID 19644491 DOI: 10.1038/Mt.2009.162  0.319
2009 Müller LU, Williams DA. Finding the needle in the hay stack: hematopoietic stem cells in Fanconi anemia. Mutation Research. 668: 141-9. PMID 19508850 DOI: 10.1016/J.Mrfmmm.2009.03.010  0.349
2009 Williams DA. Rapid development of pluripotent stem cells as a potential therapeutic modality Molecular Therapy. 17: 929-930. PMID 19483764 DOI: 10.1038/Mt.2009.97  0.321
2009 Cancelas JA, Williams DA. Rho GTPases in hematopoietic stem cell functions. Current Opinion in Hematology. 16: 249-54. PMID 19417647 DOI: 10.1097/Moh.0B013E32832C4B80  0.323
2009 Williams DA. Recombinant DNA advisory committee updates recommendations on gene transfer for X-linked severe combined immunodeficiency Molecular Therapy. 17: 751-752. PMID 19404322 DOI: 10.1038/Mt.2009.76  0.316
2009 Müller LUW, Daley GQ, Williams DA. Upping the ante: recent advances in direct reprogramming. Molecular Therapy. 17: 947-953. PMID 19337233 DOI: 10.1038/Mt.2009.72  0.334
2009 Williams DA. Progress in genetic therapy for severe combined immunodeficiency associated with adenosine deaminase deficiency Molecular Therapy. 17: 577-578. PMID 19337228 DOI: 10.1038/Mt.2009.57  0.337
2009 Williams DA. ESCGT 2008: Progress in clinical gene therapy Molecular Therapy. 17: 1-2. PMID 19116631 DOI: 10.1038/Mt.2008.277  0.364
2009 Sanchez-Aguilera A, Lee Y, Lo Celso C, Brumme K, Lin CP, Scadden DT, Williams DA. Regulation of Rho GTPases by the Hematopoietic-Specific Guanine Nucleotide Exchange Factor Vav1 Is Critical for Hematopoietic Stem Cell Retention in the Endosteal Niche and Engraftment. Blood. 114: 80-80. DOI: 10.1182/Blood.V114.22.80.80  0.35
2009 Chang K, Sanchez-Aguilera A, Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas J. Vav3 and Rac2 Activation Are Required for B Progenitor Transformation Induced by p190-BCR-ABL. Blood. 114: 449-449. DOI: 10.1182/Blood.V114.22.449.449  0.317
2009 Mizukawa B, Wei J, Wunderlich M, Chou F, Zheng Y, Williams DA, Mulloy JC. Bcl-XL Is a Critical Mediator of Rac Signaling in MLL-AF9-Induced Acute Myeloid Leukemia. Blood. 114: 1971-1971. DOI: 10.1182/Blood.V114.22.1971.1971  0.335
2009 Milsom MD, Yabuuchi A, Daley GQ, Williams DA. The Rho GTPase Rac1 Is Not Required for Definitive Hematopoietic Specification in ES-Derived Hematopoiesis. Blood. 114: 1494-1494. DOI: 10.1182/Blood.V114.22.1494.1494  0.315
2009 Lane SW, Celso CL, Sykes SM, Shterental S, Paktinat M, Lin CP, Williams DA, Scadden DT, Gilliland DG. Leukemia Stem Cells Are Resistant to In Vivo, Cell Non-Autonomous Wnt Inhibition. Blood. 114: 1025-1025. DOI: 10.1182/Blood.V114.22.1025.1025  0.347
2008 Müller LU, Milsom MD, Kim MO, Schambach A, Schuesler T, Williams DA. Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca(-/-) Hematopoietic Stem Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1154-1160. PMID 28178472 DOI: 10.1038/Mt.2008.67  0.369
2008 Gan B, Sahin E, Jiang S, Sanchez-Aguilera A, Scott KL, Chin L, Williams DA, Kwiatkowski DJ, DePinho RA. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proceedings of the National Academy of Sciences of the United States of America. 105: 19384-9. PMID 19052232 DOI: 10.1073/Pnas.0810584105  0.32
2008 Milsom MD, Jerabek-Willemsen M, Harris CE, Schambach A, Broun E, Bailey J, Jansen M, Schleimer D, Nattamai K, Wilhelm J, Watson A, Geiger H, Margison GP, Moritz T, Baum C, ... ... Williams DA, et al. Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells. Cancer Research. 68: 6171-80. PMID 18676840 DOI: 10.1158/0008-5472.Can-08-0320  0.304
2008 Müller LU, Schore RJ, Zheng Y, Thomas EK, Kim MO, Cancelas JA, Gu Y, Williams DA. Rac guanosine triphosphatases represent a potential target in AML. Leukemia. 22: 1803-6. PMID 18668135 DOI: 10.1038/Leu.2008.196  0.362
2008 Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y. Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development Blood. 112: 1767-1775. PMID 18579797 DOI: 10.1182/Blood-2008-01-132068  0.306
2008 Zhang X, Shang X, Guo F, Murphy K, Kirby M, Kelly P, Reeves L, Smith FO, Williams DA, Zheng Y, Pang Q. Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A. Blood. 112: 1683-6. PMID 18565850 DOI: 10.1182/Blood-2008-03-147090  0.347
2008 Yamada Y, Sanchez-Aguilera A, Brandt EB, McBride M, Al-Moamen NJ, Finkelman FD, Williams DA, Cancelas JA, Rothenberg ME. FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood. 112: 2500-7. PMID 18539901 DOI: 10.1182/Blood-2007-11-126268  0.313
2008 Sadelain M, Williams DA. A "vector drain" in US gene therapy development? Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 801-2. PMID 18432266 DOI: 10.1038/Mt.2008.71  0.455
2008 Williams DA, Zheng Y, Cancelas JA. Rho GTPases and regulation of hematopoietic stem cell localization. Methods in Enzymology. 439: 365-93. PMID 18374178 DOI: 10.1016/S0076-6879(07)00427-2  0.36
2008 Thornhill SI, Schambach A, Howe SJ, Ulaganathan M, Grassman E, Williams D, Schiedlmeier B, Sebire NJ, Gaspar HB, Kinnon C, Baum C, Thrasher AJ. Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 590-8. PMID 18180772 DOI: 10.1038/Sj.Mt.6300393  0.304
2008 Grimes HL, Velu CS, Horman S, Chaubey A, Bourdeau T, Xu H, Zhu J, Paul W, Colmenares C, Williams DA, Gebelein B. Gfi1 as a Regulator of Hematopoietic Differentiation. Blood. 112: sci-16-sci-16. DOI: 10.1182/Blood.V112.11.Sci-16.Sci-16  0.325
2008 Xu H, Geiger H, Szczur K, Deira D, Zheng Y, Settleman J, Srour E, Williams DA, Filippi M. Absence of the Rho GTPase Activating Protein p190-B Enhances Long Term Hematopoietic Stem Cell Engraftment Blood. 112: 614-614. DOI: 10.1182/Blood.V112.11.614.614  0.337
2008 Grassman E, Higashimoto T, Rohrbach J, Hall D, Williams DA, Reeves L, Malik P. Pulmozyme® Treatment of Vectors Produced by Transient Transfection Reduces Residual Plasmid DNA on Human CD34+ Hematopoietic Progenitor Cells without Loss of Transduction or Engraftment Efficiency Blood. 112: 4626-4626. DOI: 10.1182/Blood.V112.11.4626.4626  0.343
2008 Sanchez-Aguilera A, Sengupta At, Mastin JP, Chang KH, Williams DA, Cancelas JA. Rac2 GTPase Activation Is Necessary for Development of p190-BCR-ABL-Induced B-Cell Acute Lymphoblastic Leukemia Blood. 112: 3790-3790. DOI: 10.1182/Blood.V112.11.3790.3790  0.301
2008 Wei J, Wunderlich M, Harris C, Mizukawa B, Zheng Y, Williams DA, Mulloy JC. Rac GTPases Are Required for MLL-AF9-Induced Mixed Lineage Leukemia. Blood. 112: 3368-3368. DOI: 10.1182/Blood.V112.11.3368.3368  0.356
2008 Velu CS, Berk M, Xu H, Bourdeau T, Kazanjian A, Williams DA, Colmenares C, Grimes HL. The Ski oncoprotein regulates Hematopoietic Stem Cell Fitness and Functions as a Corepressor for Gfi1. Blood. 112: 1403-1403. DOI: 10.1182/Blood.V112.11.1403.1403  0.337
2008 Zhang X, Shang X, Guo F, Murphy K, Kirby M, Kelly P, Reeves L, Smith FO, Williams DA, Zheng Y, Pang Q. A Cell-Autonomous Defect of Bone Marrow Hematopoietic Stem/Progenitor Cells and Impaired Stromal Function in FA-a Patients Blood. 112: 1364-1364. DOI: 10.1182/Blood.V112.11.1364.1364  0.356
2007 Williams DA. An international conversation on stem cell gene therapy Molecular Therapy. 15: 2058-2059. PMID 18026181 DOI: 10.1038/Sj.Mt.6300358  0.33
2007 Yang L, Wang L, Kalfa TA, Cancelas JA, Shang X, Pushkaran S, Mo J, Williams DA, Zheng Y. Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis. Blood. 110: 3853-61. PMID 17702896 DOI: 10.1182/Blood-2007-03-079582  0.346
2007 Ball CR, Pilz IH, Schmidt M, Fessler S, Williams DA, Von Kalle C, Glimm H. Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression Blood. 110: 1779-1787. PMID 17496202 DOI: 10.1182/Blood-2006-11-053710  0.341
2007 Milsom MD, Williams DA. Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection. Dna Repair. 6: 1210-21. PMID 17482893 DOI: 10.1016/J.Dnarep.2007.03.020  0.359
2007 Zhang X, Sejas DP, Qiu Y, Williams DA, Pang Q. Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence. Journal of Cell Science. 120: 1572-83. PMID 17405815 DOI: 10.1242/Jcs.003152  0.307
2007 Williams DA. Are lentivirus vectors safer? Molecular Therapy. 15: 439. PMID 17311027 DOI: 10.1038/Sj.Mt.6300111  0.313
2007 Will E, Bailey J, Schuesler T, Modlich U, Balcik B, Burzynski B, Witte D, Layh-Schmitt G, Rudolph C, Schlegelberger B, von Kalle C, Baum C, Sorrentino BP, Wagner LM, Kelly P, ... ... Williams DA, et al. Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 782-91. PMID 17299409 DOI: 10.1038/Sj.Mt.6300083  0.335
2007 Williams DA, Cancelas JA. Leukaemia: niche retreats for stem cells. Nature. 444: 827-8. PMID 17167463 DOI: 10.1038/444827A  0.327
2007 Kelly PF, Radtke S, von Kalle C, Balcik B, Bohn K, Mueller R, Schuesler T, Haren M, Reeves L, Cancelas JA, Leemhuis T, Harris R, Auerbach AD, Smith FO, Davies SM, ... Williams DA, et al. Stem cell collection and gene transfer in Fanconi anemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 211-9. PMID 17164793 DOI: 10.1038/Sj.Mt.6300033  0.346
2007 Williams DA, Xu H, Cancelas JA. Children are not little adults: just ask their hematopoietic stem cells. The Journal of Clinical Investigation. 116: 2593-6. PMID 17016556 DOI: 10.1172/Jci30083  0.347
2007 Thomas EK, Cancelas JA, Chae H, Cox AD, Keller PJ, Perrotti D, Neviani P, Druker BJ, Zheng Y, Harris CE, Williams DA. Rac GTPases Are Potential Therapeutic Targets in p210-BCR-ABL-Induced Myeloproliferative Disease (MPD). Blood. 110: 465-465. DOI: 10.1182/Blood.V110.11.465.465  0.35
2007 Velu CS, Porteous S, Xu H, Baktula AM, Roehrs P, Bourdeau T, Stavnezer E, Williams D, Colmenares C, Grimes HL. microRNA Control of Hematopoietic Stem Cell Fitness and Myelopoiesis. Blood. 110: 373-373. DOI: 10.1182/Blood.V110.11.373.373  0.304
2007 Muller LU, Milsom M, Harris CE, Bailey J, Williams DA. The Sooner the Better: Rapid Transduction Enhances the Engraftment/Selection of Gene Corrected Fanconi Anemia HSC. Blood. 110: 194-194. DOI: 10.1182/Blood.V110.11.194.194  0.381
2006 Debidda M, Williams DA, Zheng Y. Rac1 GTPase regulates cell genomic stability and senescence. The Journal of Biological Chemistry. 281: 38519-28. PMID 17032649 DOI: 10.1074/Jbc.M604607200  0.322
2006 Cancelas JA, Jansen M, Williams DA. The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization. Experimental Hematology. 34: 976-85. PMID 16863904 DOI: 10.1016/J.Exphem.2006.03.016  0.309
2006 Ghiaur G, Lee A, Bailey J, Cancelas JA, Zheng Y, Williams DA. Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment. Blood. 108: 2087-94. PMID 16709932 DOI: 10.1182/Blood-2006-02-001560  0.337
2006 Guo F, Debidda M, Yang L, Williams DA, Zheng Y. Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly. The Journal of Biological Chemistry. 281: 18652-9. PMID 16698790 DOI: 10.1074/Jbc.M603508200  0.302
2006 Cornetta K, Croop J, Dropcho E, Abonour R, Kieran MW, Kreissman S, Reeves L, Erickson LC, Williams DA. A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase. Cancer Gene Therapy. 13: 886-95. PMID 16645619 DOI: 10.1038/Sj.Cgt.7700963  0.342
2006 Williams DA. An emerging consensus on recommendations to facilitate clinical gene transfer Molecular Therapy. 13: 637-638. PMID 16530487 DOI: 10.1016/J.Ymthe.2006.03.003  0.304
2006 Cancelas JA, Williams DA. Stem cell mobilization by beta2-agonists. Nature Medicine. 12: 278-9. PMID 16520770 DOI: 10.1038/Nm0306-278  0.32
2006 Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y. Rational design and applications of a Rac GTPase-specific small molecule inhibitor. Methods in Enzymology. 406: 554-65. PMID 16472687 DOI: 10.1016/S0076-6879(06)06043-5  0.318
2006 Will E, Speidel D, Wang Z, Ghiaur G, Rimek A, Schiedlmeier B, Williams DA, Baum C, Ostertag W, Klump H. HOXB4 inhibits cell growth in a dose-dependent manner and sensitizes cells towards extrinsic cues. Cell Cycle (Georgetown, Tex.). 5: 14-22. PMID 16357528 DOI: 10.4161/Cc.5.1.2304  0.321
2006 Schambach A, Bohne J, Chandra S, Will E, Margison GP, Williams DA, Baum C. Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 391-400. PMID 16226060 DOI: 10.1016/J.Ymthe.2005.08.012  0.301
2006 Korhonen M, Zhao H, Faccio R, Ross PF, Hopkins TM, Cancelas JA, Williams DA. Rac1 and Rac2 GTPases Play Distinct Roles and Are Essential for Full Osteoclast Differentiation. Blood. 108: 4231-4231. DOI: 10.1182/Blood.V108.11.4231.4231  0.328
2006 Yamada Y, Rothenberg ME, Lee AW, Al-Moamen NJ, Williams DA, Cancelas JA. SCF and IL-5 Synergize with FIP1L1/PDGFRα To Induce Mastocytosis in a Chronic Eosinophilic Leukemia Murine Model. Blood. 108: 3631-3631. DOI: 10.1182/Blood.V108.11.3631.3631  0.305
2006 Ball CR, Schmidt M, Pilz IH, Sylvia F, Williams DA, Kalle Cv, Glimm H. Stable Polyclonal Murine Long-Term Hematopoiesis without Clonal Exhaustion of MGMT P140K Expressing Murine Hematopoietic Stem Cells after Extended Reduced Intensity Selection. Blood. 108: 3271-3271. DOI: 10.1182/Blood.V108.11.3271.3271  0.37
2006 Lee AW, Milsom MD, Zheng Y, Cancelas JA, Williams DA. Improved Engraftment of Bone Marrow and Mobilized Peripheral Blood Stem Cells in a Fanconi Anemia Murine Model. Blood. 108: 3186-3186. DOI: 10.1182/Blood.V108.11.3186.3186  0.303
2006 Xu H, Szczur K, Zheng Y, Settleman J, Williams DA, Filippi M. P190-B RhoGAP Is Critical for Hematopoietic Stem/Progenitor Cell Homing and Short Term Engraftment. Blood. 108: 1341-1341. DOI: 10.1182/Blood.V108.11.1341.1341  0.314
2006 Kelly P, Balcik B, Bohn K, Mueller R, Schuesler T, Reeves L, Leemhuis T, Harris R, Davies S, Smith F, von Kalle C, Williams D. 682. Collection and Genetic Correction of Fanconi Complement Type A Hematopoietic Stem Cells: Results of Two Pilot Studies Molecular Therapy. 13: S263. DOI: 10.1016/J.Ymthe.2006.08.759  0.344
2006 Will E, Bailey J, Schuesler T, Balcik B, Burzynski B, Witte D, Layh-Schmitt G, vonKalle C, Baum C, Sorrentino BP, Wagner LM, Reeves L, Williams DA. 459. Murine Study To Evaluate Long-Term Transgene Expression of the MSCV-MGMTP140K wc Retroviral Vector in Support of a Phase I Gene Transfer Trial-Limitations of the Murine Model as a Pre-Clinical Tool Molecular Therapy. 13: S177-S178. DOI: 10.1016/J.Ymthe.2006.08.528  0.322
2006 Worsham DN, Wang D, von Kalle C, Williams DA, Pan D. 97. Translational Studies toward Optimizing In Vivo Bone Marrow Stem Cell Gene Transfer Using Lentiviral Vector Molecular Therapy. 13: S40. DOI: 10.1016/J.Ymthe.2006.08.116  0.348
2006 Yamada Y, Cancelas J, Lee A, Williams D, Rothenberg M. FIP1L1-PDGFRα Induces Stem Cell Factor Dependent Eosinophil and Mast Cell Development from Murine Hematopoietic Stem Cell/Progenitors in Vitro Journal of Allergy and Clinical Immunology. 117: S271. DOI: 10.1016/J.Jaci.2005.12.1070  0.321
2005 Villella AD, Yao J, Getty RR, Juliar BE, Yiannoutsos C, Hartwell JR, Cai S, Sadat MA, Cornetta K, Williams DA, Pollok KE. Real-Time PCR: an Effective Tool for Measuring Transduction Efficiency in Human Hematopoietic Progenitor Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 483-491. PMID 28192683 DOI: 10.1016/J.Ymthe.2004.10.017  0.319
2005 Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA. Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization. Nature Medicine. 11: 886-91. PMID 16025125 DOI: 10.1038/Nm1274  0.331
2005 Gu Y, Zheng Y, Williams DA. RhoH GTPase: a key regulator of hematopoietic cell proliferation and apoptosis? Cell Cycle (Georgetown, Tex.). 4: 201-2. PMID 15611634 DOI: 10.4161/Cc.4.2.1490  0.32
2005 Filippi M, Szczur K, Xu H, Zheng Y, Settleman J, Williams DA. Regulation of the Rho GTPase, RhoA, Activity Is Critical for Erythropoiesis during Embryo Development. Blood. 106: 829-829. DOI: 10.1182/Blood.V106.11.829.829  0.313
2005 Filippi M, Xu H, Szczur K, Zheng Y, Williams DA. Rho GTPase CDC42 Signals Separately Regulate Directed Migration Versus Random Movement in Neutrophil. Blood. 106: 636-636. DOI: 10.1182/Blood.V106.11.636.636  0.304
2005 Filippi M, Berclaz P, Szczur K, Harris C, Williams DA. Cross Talk between Rho GTPases Is Critical for Hematopoietic-Derived Inflammatory Processes. Blood. 106: 631-631. DOI: 10.1182/Blood.V106.11.631.631  0.322
2005 Kelly P, Balcik B, Bohn K, Mueller R, Jurickova I, Schuesler T, Reeves L, Leemhuis T, Harris R, Davies SM, Smith FO, von Kalle C, Williams DA. Early Results of the Clinical Collection and Genetic Correction of Fanconi Complement Type A Hematopoietic Stem Cells. Blood. 106: 1283-1283. DOI: 10.1182/Blood.V106.11.1283.1283  0.345
2005 Schore RJ, Zheng Y, Williams DA, Gu Y. Inhibition of the Rho GTPase, Rac, Differentially Inhibits Proliferation of AML Cell Lines and May Serve as a Novel Molecular Target. Blood. 106: 1205-1205. DOI: 10.1182/Blood.V106.11.1205.1205  0.34
2005 Schambach A, Bohne J, Chandra S, Will E, Mueller L, Margison G, Williams DA, Baum C. 829. Design of a Safe and Efficient Vector for Bone Marrow Chemoprotection by O6-Methyl-Guanine-DNA-MethylTransferase Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.372  0.328
2005 Worsham DN, Bohn K, Kuhel D, Williams DA, Kalle Cv, Pan D. 6. In Vivo Adult Stem Cell Gene Transfer in Mice by In Situ Delivery of a Self-Inactivating Lentiviral Vector Using Intrafemoral Injection Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.009  0.351
2004 von Kalle C, Baum C, Williams DA. Lenti in red: progress in gene therapy for human hemoglobinopathies. The Journal of Clinical Investigation. 114: 889-91. PMID 15467825 DOI: 10.1172/Jci200423132  0.303
2004 Baum C, von Kalle C, Staal FJ, Li Z, Fehse B, Schmidt M, Weerkamp F, Karlsson S, Wagemaker G, Williams DA. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 5-13. PMID 14741772 DOI: 10.1016/J.Ymthe.2003.10.013  0.325
2004 Filippi M, Xu H, Towe J, Harris CE, Szczur K, Wang L, Atkinson S, Zheng Y, Williams DA. The RHO GTPASE CDC42 Regulator CDC42GAP Plays a Critical Role in Neutrophil Migration Via Podosome-Like Formation. Blood. 104: 651-651. DOI: 10.1182/Blood.V104.11.651.651  0.314
2004 Pan D, von Kalle C, Williams DA, Worsham DN, Bohn K, Lutz C. In Vivo Bone Marrow Stem Cell Gene Transfer in Mice by In Situ Delivery of a 3rd-Generation Lentiviral Vector Using Intrafemoral Injection. Blood. 104: 2104-2104. DOI: 10.1182/Blood.V104.11.2104.2104  0.35
2004 Kalfa TA, Pushkaran S, Johnson JF, Wei Q, Williams DA, Zheng Y. Erythrocyte Cytoskeletal Defects Induced in Mice by Deletion of Rac GTPases. Blood. 104: 1573-1573. DOI: 10.1182/Blood.V104.11.1573.1573  0.312
2004 Cancelas JA, Lee AW, Prabhakar R, Jansen M, Zheng Y, Williams DA. Rac1 and Rac2 Rho GTPases Distinctly Regulate Stem Cell Engraftment and Mobilization and Are Novel Targets for Pharmacologically-Induced Progenitor Mobilization. Blood. 104: 115-115. DOI: 10.1182/Blood.V104.11.115.115  0.328
2003 Pollok KE, Hartwell JR, Braber A, Cooper RJ, Jansen M, Ragg S, Bailey BJ, Erickson LC, Kreklau EL, Williams DA. In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations. Human Gene Therapy. 14: 1703-14. PMID 14670122 DOI: 10.1089/104303403322611728  0.353
2003 Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science (New York, N.Y.). 302: 445-9. PMID 14564009 DOI: 10.1126/Science.1088485  0.341
2003 Tan BL, Yazicioglu MN, Ingram D, McCarthy J, Borneo J, Williams DA, Kapur R. Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells. Blood. 101: 4725-32. PMID 12560232 DOI: 10.1182/Blood-2002-08-2521  0.305
2003 Baum C, Düllmann J, Li Z, Fehse B, Meyer J, Williams DA, von Kalle C. Side effects of retroviral gene transfer into hematopoietic stem cells. Blood. 101: 2099-114. PMID 12511419 DOI: 10.1182/Blood-2002-07-2314  0.358
2003 Neff T, Horn PA, Peterson LJ, Thomasson BM, Thompson J, Williams DA, Schmidt M, Georges GE, Kalle Cv, Kiem H. Methylguanine methyltransferase–mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model Journal of Clinical Investigation. 112: 1581-1588. DOI: 10.1172/Jci200318782  0.363
2002 Gu Y, Byrne MC, Paranavitana NC, Aronow B, Siefring JE, D'Souza M, Horton HF, Quilliam LA, Williams DA. Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells. Molecular and Cellular Biology. 22: 7645-57. PMID 12370311 DOI: 10.1128/Mcb.22.21.7645-7657.2002  0.333
2002 Jansen M, Sorg UR, Ragg S, Flasshove M, Seeber S, Williams DA, Moritz T. Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells. Cancer Gene Therapy. 9: 737-46. PMID 12189523 DOI: 10.1038/Sj.Cgt.7700490  0.342
2002 Tao W, Filippi M, Bailey JR, Atkinson SJ, Connors B, Evan A, Williams DA. The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization Blood. 100: 1679-1688. DOI: 10.1182/Blood.V100.5.1679.H81702001679_1679_1688  0.302
2001 Pollok KE, van Der Loo JC, Cooper RJ, Hartwell JR, Miles KR, Breese R, Williams EP, Montel A, Seshadri R, Hanenberg H, Williams DA. Differential transduction efficiency of SCID-repopulating cells derived from umbilical cord blood and granulocyte colony-stimulating factor-mobilized peripheral blood. Human Gene Therapy. 12: 2095-108. PMID 11747599 DOI: 10.1089/10430340152677430  0.34
2001 Croop JM, Cooper R, Fernandez C, Graves V, Kreissman S, Hanenberg H, Smith FO, Williams DA. Mobilization and collection of peripheral blood CD34+ cells from patients with Fanconi anemia. Blood. 98: 2917-21. PMID 11698271 DOI: 10.1182/Blood.V98.10.2917  0.3
2001 Gu Y, Jia B, Yang FC, D'Souza M, Harris CE, Derrow CW, Zheng Y, Williams DA. Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency. The Journal of Biological Chemistry. 276: 15929-38. PMID 11278678 DOI: 10.1074/Jbc.M010445200  0.372
2000 Williams DA, Nienhuis AW, Hawley RG, Smith FO. Gene Therapy 2000. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 376-393. PMID 11701552 DOI: 10.1182/Asheducation-2000.1.376  0.354
2000 Williams DA, Smith FO. Progress in the use of gene transfer methods to treat genetic blood diseases. Human Gene Therapy. 11: 2059-66. PMID 11044908 DOI: 10.1089/104303400750001372  0.332
2000 Abonour R, Williams DA, Einhorn L, Hall KM, Chen J, Coffman J, Traycoff CM, Bank A, Kato I, Ward M, Williams SD, Hromas R, Robertson MJ, Smith FO, Woo D, et al. Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nature Medicine. 6: 652-8. PMID 10835681 DOI: 10.1038/76225  0.341
2000 Williams DA, Tao W, Yang F, Kim C, Gu Y, Mansfield P, Levine JE, Petryniak B, Derrow CW, Harris C, Jia B, Zheng Y, Ambruso DR, Lowe JB, Atkinson SJ, et al. Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency Blood. 96: 1646-1654. DOI: 10.1182/Blood.V96.5.1646.H8001646_1646_1654  0.335
2000 Gommerman JL, Sittaro D, Klebasz NZ, Williams DA, Berger SA. Differential stimulation of c-Kit mutants by membrane-bound and soluble Steel Factor correlates with leukemic potential Blood. 96: 3734-3742. DOI: 10.1182/Blood.V96.12.3734.H8003734_3734_3742  0.303
2000 Williams DA, Yang F-, Borneo JB, Pennington J, King AJ. Role of rac 2 in hemopoietic stem cell motility Experimental Hematology. 28: 128-129. DOI: 10.1016/S0301-472X(00)00497-5  0.343
2000 Yang F, Atkinson SJ, Borneo JB, Pennington J, Williams DA. The hematopoietic-specific rho gtpase, RAC2, is essential for normal adhesion and controlled movement of hematopoietic progenitor cells In vitro And In vivo Experimental Hematology. 28: 67-68. DOI: 10.1016/S0301-472X(00)00299-X  0.339
2000 Yang F, Kapur R, King A, Tao W, Borneo J, Williams D. RAC2 Regulates the activation of akt and the balance between pro- and anti-apoptotic proteins bad and bcl-xl Experimental Hematology. 28: 67. DOI: 10.1016/S0301-472X(00)00298-8  0.326
2000 Williams DA. Cells and Genes in Molecular Therapeutics Cell. 101: 145-146. DOI: 10.1016/S0092-8674(00)80821-1  0.376
1999 Williams DA. Retroviral-fibronectin interactions in transduction of mammalian cells Annals of the New York Academy of Sciences. 872: 109-114. PMID 10372115 DOI: 10.1111/J.1749-6632.1999.Tb08457.X  0.323
1999 Sellers SE, Tisdale JF, Bodine DM, Williams DA, Karlsson S, Meztger M, Donahue RE, Dunbar CE. No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells Human Gene Therapy. 10: 633-640. PMID 10094206 DOI: 10.1089/10430349950018706  0.343
1999 Roberts AW, Kim C, Zhen L, Lowe JB, Kapur R, Petryniak B, Spaetti A, Pollock JD, Borneo JB, Bradford GB, Atkinson SJ, Dinauer MC, Williams DA. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity. 10: 183-96. PMID 10072071 DOI: 10.1016/S1074-7613(00)80019-9  0.316
1999 Kapur R, Cooper R, Xiao X, Weiss MJ, Donovan P, Williams DA. The Presence of Novel Amino Acids in the Cytoplasmic Domain of Stem Cell Factor Results in Hematopoietic Defects inSteel17H Mice Blood. 94: 1915-1925. DOI: 10.1182/Blood.V94.6.1915  0.337
1999 MacNeill EC, Hanenberg H, Pollok KE, van der Loo JCM, Bierhuizen MFA, Wagemaker G, Williams DA. Simultaneous Infection with Retroviruses Pseudotyped with Different Envelope Proteins Bypasses Viral Receptor Interference Associated with Colocalization of gp70 and Target Cells on Fibronectin CH-296 Journal of Virology. 73: 3960-3967. DOI: 10.1128/Jvi.73.5.3960-3967.1999  0.305
1998 van der Loo JC, Xiao X, McMillin D, Hashino K, Kato I, Williams DA. VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin. The Journal of Clinical Investigation. 102: 1051-61. PMID 9727075 DOI: 10.1172/Jci3687  0.332
1998 Du X, Williams DA. Update on development of interleukin-11. Current Opinion in Hematology. 2: 182-8. PMID 9371993 DOI: 10.1097/00062752-199502030-00005  0.342
1998 Veena P, Traycoff CM, Williams DA, McMahel J, Rice S, Cornetta K, Srour EF. Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34+ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes Blood. 91: 3693-3701. DOI: 10.1182/Blood.V91.10.3693  0.31
1997 Longley BJ, Tyrrell L, Ma Y, Williams DA, Halaban R, Langley K, Lu HS, Schechter NM. Chymase cleavage of stem cell factor yields a bioactive, soluble product. Proceedings of the National Academy of Sciences of the United States of America. 94: 9017-21. PMID 9256427 DOI: 10.1073/Pnas.94.17.9017  0.32
1997 Kapur R, Everett ET, Uffman J, McAndrews-Hill M, Cooper R, Ryder J, Vik T, Williams DA. Overexpression of Human Stem Cell Factor Impairs Melanocyte, Mast Cell, and Thymocyte Development: A Role for Receptor Tyrosine Kinase-Mediated Mitogen Activated Protein Kinase Activation in Cell Differentiation Blood. 90: 3018-3026. DOI: 10.1182/Blood.V90.8.3018  0.324
1996 Larochelle A, Vormoor J, Hanenberg H, Wang JCY, Bhatia M, Lapidot T, Moritz T, Murdoch B, Xiao XL, Kato I, Williams DA, Dick JE. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy Nature Medicine. 2: 1329-1337. PMID 8946831 DOI: 10.1038/Nm1296-1329  0.353
1996 Hanenberg H, Xiao XL, Dilloo D, Hashino K, Kato I, Williams DA. Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nature Medicine. 2: 876-82. PMID 8705856 DOI: 10.1038/Nm0896-876  0.332
1996 Maze R, Carney JP, Kelley MR, Glassner BJ, Williams DA, Samson L. Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent Proceedings of the National Academy of Sciences of the United States of America. 93: 206-210. PMID 8552605 DOI: 10.1073/Pnas.93.1.206  0.659
1996 Rackoff W, Orazi A, Robinson C, Cooper R, Alter B, Freedman M, Harris R, Williams D. Prolonged administration of granulocyte colony-stimulating factor (filgrastim) to patients with Fanconi anemia: a pilot study Blood. 88: 1588-1593. DOI: 10.1182/Blood.V88.5.1588.1588  0.3
1996 Moritz T, Dutt P, Xiao X, Carstanjen D, Vik T, Hanenberg H, Williams D. Fibronectin improves transduction of reconstituting hematopoietic stem cells by retroviral vectors: evidence of direct viral binding to chymotryptic carboxy-terminal fragments Blood. 88: 855-862. DOI: 10.1182/Blood.V88.3.855.Bloodjournal883855  0.352
1996 Majumdar M, Everett E, Xiao X, Cooper R, Langley K, Kapur R, Vik T, Williams D. Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations Blood. 87: 3203-3211. DOI: 10.1182/Blood.V87.8.3203.Bloodjournal8783203  0.313
1995 Williams DA, Moritz T. Genetic manipulation of hematopoietic stem cells in adenosine deaminase deficiency. Advances in Experimental Medicine and Biology. 370: 395-400. PMID 7660937 DOI: 10.1007/978-1-4615-2584-4_86  0.334
1995 Yoder M, King B, Hiatt K, Williams D. Murine embryonic yolk sac cells promote in vitro proliferation of bone marrow high proliferative potential colony-forming cells Blood. 86: 1322-1330. DOI: 10.1182/Blood.V86.4.1322.Bloodjournal8641322  0.322
1995 Du X, Scott D, Yang Z, Cooper R, Xiao X, Williams D. Interleukin-11 stimulates multilineage progenitors, but not stem cells, in murine and human long-term marrow cultures Blood. 86: 128-134. DOI: 10.1182/Blood.V86.1.128.Bloodjournal861128  0.311
1994 Moritz T, Patel VP, Williams DA. Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors. The Journal of Clinical Investigation. 93: 1451-7. PMID 8163649 DOI: 10.1172/Jci117122  0.344
1994 Yoder M, Papaioannou V, Breitfeld P, Williams D. Murine yolk sac endoderm- and mesoderm-derived cell lines support in vitro growth and differentiation of hematopoietic cells Blood. 83: 2436-2443. DOI: 10.1182/Blood.V83.9.2436.2436  0.336
1993 Bodine DM, Moritz T, Donahue RE, Luskey BD, Kessler SW, Martin DI, Orkin SH, Nienhuis AW, Williams DA. Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells. Blood. 82: 1975-80. PMID 7691243 DOI: 10.1182/Blood.V82.7.1975.Bloodjournal8271975  0.367
1993 Yoder M, Du X, Williams D. High proliferative potential colony-forming cell heterogeneity identified using counterflow centrifugal elutriation Blood. 82: 385-391. DOI: 10.1182/Blood.V82.2.385.Bloodjournal822385  0.315
1992 Toksoz D, Zsebo KM, Smith KA, Hu S, Brankow D, Suggs SV, Martin FH, Williams DA. Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 7350-4. PMID 1380155 DOI: 10.1073/Pnas.89.16.7350  0.348
1992 Sieff CA, Yokoyama CT, Zsebo KM, Trammell J, Andersen JW, Nathan DG, Williams DA. The production of steel factor mRNA in Diamond-Blackfan anaemia long-term cultures and interactions of steel factor with erythropoietin and interleukin-3. British Journal of Haematology. 82: 640-7. PMID 1282827 DOI: 10.1111/J.1365-2141.1992.Tb06938.X  0.307
1992 Luskey B, Rosenblatt M, Zsebo K, Williams D. Stem cell factor, interleukin-3, and interleukin-6 promote retroviral- mediated gene transfer into murine hematopoietic stem cells Blood. 80: 396-402. DOI: 10.1182/Blood.V80.2.396.Bloodjournal802396  0.307
1991 Luskey BD, Lim B, Apperley JF, Orkin SH, Williams DA. Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells. Annals of the New York Academy of Sciences. 612: 398-406. PMID 2291566 DOI: 10.1111/J.1749-6632.1990.Tb24327.X  0.361
1991 Williams DA, Rios M, Stephens C, Patel VP. Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature. 352: 438-41. PMID 1861722 DOI: 10.1038/352438A0  0.32
1991 Apperley J, Luskey B, Williams D. Retroviral gene transfer of human adenosine deaminase in murine hematopoietic cells: effect of selectable marker sequences on long-term expression Blood. 78: 310-317. DOI: 10.1182/Blood.V78.2.310.Bloodjournal782310  0.353
1991 Paul S, Yang Y, Donahue R, Goldring S, Williams D. Stromal cell-associated hematopoiesis: immortalization and characterization of a primate bone marrow-derived stromal cell line Blood. 77: 1723-1733. DOI: 10.1182/Blood.V77.8.1723.Bloodjournal7781723  0.338
1990 Apperley JF, Williams DA. Gene therapy: current status and future directions. British Journal of Haematology. 75: 148-55. PMID 2196929 DOI: 10.1111/J.1365-2141.1990.Tb02641.X  0.316
1990 Paul SR, Bennett F, Calvetti JA, Kelleher K, Wood CR, O'Hara RM, Leary AC, Sibley B, Clark SC, Williams DA. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proceedings of the National Academy of Sciences of the United States of America. 87: 7512-6. PMID 2145578 DOI: 10.1073/Pnas.87.19.7512  0.317
1990 Williams DA. Expression of introduced genetic sequences in hematopoietic cells following retroviral-mediated gene transfer Human Gene Therapy. 1: 229-239. PMID 1964394 DOI: 10.1089/Hum.1990.1.3-229  0.351
1990 Rios M, Williams DA. Systematic analysis of the ability of stromal cell lines derived from different murine adult tissues to support maintenance of hematopoietic stem cells in vitro Journal of Cellular Physiology. 145: 434-443. PMID 1703166 DOI: 10.1002/Jcp.1041450307  0.349
1990 Zsebo KM, Williams DA, Geissler EN, Broudy VC, Martin FH, Atkins HL, Hsu RY, Birkett NC, Okino KH, Murdock DC. Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell. 63: 213-24. PMID 1698556 DOI: 10.1016/0092-8674(90)90302-U  0.309
1990 Corey C, DeSilva A, Holland C, Williams D. Serial transplantation of methotrexate-resistant bone marrow: protection of murine recipients from drug toxicity by progeny of transduced stem cells Blood. 75: 337-343. DOI: 10.1182/Blood.V75.2.337.Bloodjournal752337  0.356
1989 Lim B, Apperley JF, Orkin SH, Williams DA. Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America. 86: 8892-8896. PMID 2573068 DOI: 10.1073/Pnas.86.22.8892  0.339
1988 Williams DA, Rosenblatt MF, Beier DR, Cone RD. Generation of murine stromal cell lines supporting hematopoietic stem cell proliferation by use of recombinant retrovirus vectors encoding simian virus 40 large T antigen. Molecular and Cellular Biology. 8: 3864-71. PMID 2851729 DOI: 10.1128/Mcb.8.9.3864  0.582
1988 Williams D, Lim B, Spooncer E, Longtine J, Dexter T. Restriction of expression of an integrated recombinant retrovirus in primary but not immortalized murine hematopoietic stem cells. Blood. 71: 1738-1743. DOI: 10.1182/Blood.V71.6.1738.Bloodjournal7161738  0.323
1988 Williams DA. Gene Transfer and the Prospects for Somatic Gene Therapy Hematology/Oncology Clinics of North America. 2: 277-287. DOI: 10.1016/S0889-8588(18)30621-X  0.305
1987 Lim B, Williams DA, Orkin SH. Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo Molecular and Cellular Biology. 7: 3459-3465. PMID 3683389 DOI: 10.1128/Mcb.7.10.3459  0.326
1987 Williams DA, Hsieh K, DeSilva A, Mulligan RC. Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow. The Journal of Experimental Medicine. 166: 210-8. PMID 3298524 DOI: 10.1084/Jem.166.1.210  0.553
1986 Williams DA, Orkin SH, Mulligan RC. Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 83: 2566-70. PMID 3458218 DOI: 10.1073/Pnas.83.8.2566  0.525
1984 Williams DA, Lemischka IR, Nathan DG, Mulligan RC. Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature. 310: 476-80. PMID 6087158 DOI: 10.1038/310476A0  0.661
Low-probability matches (unlikely to be authored by this person)
2020 Verboon JM, Mahmut D, Kim AR, Nakamura M, Abdulhay NJ, Nandakumar SK, Gupta N, Akie TE, Geddis AE, Manes B, Kapp ME, Hofmann I, Gabriel SB, Klein DE, Williams DA, et al. Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction. Journal of Clinical Immunology. PMID 32303876 DOI: 10.1007/S10875-020-00778-7  0.3
2003 Leurs C, Jansen M, Pollok KE, Heinkelein M, Schmidt M, Wissler M, Lindemann D, Von Kalle C, Rethwilm A, Williams DA, Hanenberg H. Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells. Human Gene Therapy. 14: 509-19. PMID 12718762 DOI: 10.1089/104303403764539305  0.3
1993 Du X, Neben T, Goldman S, Williams D. Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: acceleration of recovery of peripheral blood neutrophils and platelets Blood. 81: 27-34. DOI: 10.1182/Blood.V81.1.27.Bloodjournal81127  0.299
2001 Panchal RG, Williams DA, Kitchener PD, Reilly AM, Khan J, Bowser DN, Petrou S. Gene transfer: manipulating and monitoring function in cells and tissues. Clinical and Experimental Pharmacology & Physiology. 28: 687-91. PMID 11473537 DOI: 10.1046/J.1440-1681.2001.03504.X  0.299
2007 Kalfa TA, Pushkaran S, Cancelas JA, Johnson JF, Daria D, Geiger H, Williams DA, Zheng Y. Rac GTPases Regulate Erythropoiesis Both in the Early Steps of Differentiation and in Enucleation. Blood. 110: 1714-1714. DOI: 10.1182/Blood.V110.11.1714.1714  0.299
2020 Kan LK, Seneviratne S, Drummond KJ, Williams DA, O'Brien TJ, Monif M. P2X7 receptor antagonism inhibits tumour growth in human high-grade gliomas. Purinergic Signalling. PMID 32583309 DOI: 10.1007/S11302-020-09705-2  0.299
1997 Dutt P, Hanenberg H, Vik T, Williams DA, Yoder MC. A recombinant human fibronectin fragment facilitates retroviral mediated gene transfer into human hematopoietic progenitor cells Biochemistry and Molecular Biology International. 42: 909-917. PMID 9285058 DOI: 10.1080/15216549700203351  0.299
2014 Lehmann LE, Williams DA, London WB, Agarwal S. Full Donor Myeloid Engraftment with Minimal Toxicity in Dyskeratosis Congenita Patients Undergoing Allogeneic Bone Marrow Transplantation without Radiation or Alkylating Agents Blood. 124: 2941-2941. DOI: 10.1182/Blood.V124.21.2941.2941  0.299
2014 Brendel C, Guda S, Renella R, Du P, Bauer DE, Canver MC, Kamran SC, Thornton J, de Boer H, Milsom MD, Orkin SH, Gregory R, Williams DA. Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies Blood. 124: 2150-2150. DOI: 10.1182/Blood.V124.21.2150.2150  0.299
2012 Brennig S, Rattmann I, Lachmann N, Schambach A, Williams DA, Moritz T. In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application. Cytotherapy. 14: 451-60. PMID 22242831 DOI: 10.3109/14653249.2011.646043  0.298
2011 Nieborowska-Skorska M, Kopinski P, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Ambrozek M, Seferynska I, Niesiobedzka-Krezel J, Bolton E, ... ... Williams DA, et al. Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells Blood. 118: 2736-2736. DOI: 10.1182/Blood.V118.21.2736.2736  0.297
2006 Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y. Structure-function based design of small molecule inhibitors targeting Rho family GTPases. Current Topics in Medicinal Chemistry. 6: 1109-16. PMID 16842149 DOI: 10.2174/156802606777812095  0.297
2007 Ghiaur G, Ferkowicz MJ, Milsom MD, Bailey J, Witte D, Cancelas JA, Yoder MC, Williams DA. Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells. Blood. 111: 3313-21. PMID 18083846 DOI: 10.1182/Blood-2007-08-110114  0.297
2016 Wang F, Gao C, Lu J, Tatetsu H, Williams DA, Müller LU, Cui W, Chai L. Leukemic survival factor SALL4 contributes to defective DNA damage repair. Oncogene. PMID 27132514 DOI: 10.1038/Onc.2016.146  0.297
2003 Woods EJ, Liu J, Pollok K, Hartwell J, Smith FO, Williams DA, Yoder MC, Critser JK. A theoretically optimized method for cord blood stem cell cryopreservation. Journal of Hematotherapy & Stem Cell Research. 12: 341-50. PMID 12857375 DOI: 10.1089/152581603322023070  0.297
2009 Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P, Williams DA, Wikenheiser-Brokamp KA, Duensing S, Wells SI. Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture. Oncogene. 28: 674-85. PMID 19015634 DOI: 10.1038/Onc.2008.416  0.297
1990 Fletcher F, Williams D, Maliszewski C, Anderson D, Rives M, Belmont J. Murine leukemia inhibitory factor enhances retroviral-vector infection efficiency of hematopoietic progenitors. Blood. 76: 1098-1103. DOI: 10.1182/Blood.V76.6.1098.Bloodjournal7661098  0.297
2013 Troeger A, Chae HD, Senturk M, Wood J, Williams DA. A unique carboxyl-terminal insert domain in the hematopoietic-specific, GTPase-deficient Rho GTPase RhoH regulates post-translational processing. The Journal of Biological Chemistry. 288: 36451-62. PMID 24189071 DOI: 10.1074/Jbc.M113.505727  0.296
2004 Gu Y, Alvares CJ, Jasti AC, Jansen M, Bean J, Jegga AG, Aronow BJ, Williams DA. Alteration of RhoH Expression Is Associated with Human Diffuse Large B-Cell Lymphoma. Blood. 104: 4298-4298. DOI: 10.1182/Blood.V104.11.4298.4298  0.296
1998 Pollok KE, Hanenberg H, Noblitt TW, Schroeder WL, Kato I, Emanuel D, Williams DA. High-Efficiency Gene Transfer into Normal and Adenosine Deaminase-Deficient T Lymphocytes Is Mediated by Transduction on Recombinant Fibronectin Fragments Journal of Virology. 72: 4882-4892. DOI: 10.1128/Jvi.72.6.4882-4892.1998  0.295
2006 Kalfa TA, Pushkaran S, Cancelas JA, Jansen M, Johnson JF, Hebel K, Williams DA, Zheng Y. Deficiency of Rac1 and Rac2 GTPases Perturbs Erythroid Proliferation and Differentiation but Not Enucleation. Blood. 108: 467-467. DOI: 10.1182/Blood.V108.11.467.467  0.295
2008 Li J, Sejas DP, Zhang X, Qiu Y, Nattamai KJ, Rani R, Rathbun KR, Geiger H, Williams DA, Bagby GC, Pang Q. TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. The Journal of Clinical Investigation. 117: 3283-95. PMID 17960249 DOI: 10.1172/Jci31772  0.295
2012 Mehta P, Davies S, Duncan C, Guinan E, Klein E, Edwards S, Lehmann L, Margolis D, Williams D, Boulad F. Chemotherapy-Only Preparative Regimen for Alternative Donor Hematopoietic Stem Cell Transplantation for Patients with Fanconi Anemia Biology of Blood and Marrow Transplantation. 18: S301-S302. DOI: 10.1016/J.Bbmt.2011.12.252  0.295
2012 Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, Ficker AM, Dunn SK, Kuenzi AM, Arnett JL, Santho RA, Agirre X, Perentesis JP, Deininger MW, Zheng Y, Bustelo XR, ... Williams DA, et al. Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. Blood. 120: 800-11. PMID 22692505 DOI: 10.1182/Blood-2011-06-361709  0.295
2007 Thomas EK, Cancelas JA, Chae HD, Cox AD, Keller PJ, Perrotti D, Neviani P, Druker BJ, Setchell KD, Zheng Y, Harris CE, Williams DA. Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell. 12: 467-78. PMID 17996650 DOI: 10.1016/J.Ccr.2007.10.015  0.294
2017 De Vita S, Li Y, Harris CE, McGuinness MK, Ma C, Williams DA. The gp130 Cytokine IL-11 Regulates Engraftment of Vav1-/- Hematopoietic Stem and Progenitor Cells in Lethally Irradiated Recipients. Stem Cells (Dayton, Ohio). PMID 29235178 DOI: 10.1002/Stem.2760  0.294
1995 Clapp DW, Williams DA. The use of umbilical cord blood as a cellular source for correction of genetic diseases affecting the hematopoietic system Stem Cells. 13: 613-621. PMID 8590863 DOI: 10.1002/Stem.5530130606  0.294
2016 Vusirikala M, Naik S, Maziarz RT, Baumeister S, Aquino V, Ma H, Moseley A, Woolfrey AE, Krishnamurti L, Chen GL, Sandmaier BM, Bertaina A, Perales M, Williams DA, Kapoor N. BPX-501 Cells (Donor T Cells Transduced with iC9 Suicide Gene) Treatment Following TCR Alpha Beta Depleted Stem Cell Transplantation in Adults and Children with Hematological Disorders Biology of Blood and Marrow Transplantation. 22: S361. DOI: 10.1016/J.Bbmt.2015.11.863  0.294
2014 Forester C, Sartain SE, Guo D, Harris M, Weinberg O, Fleming MD, London WB, Williams DA, Hofmann I. Pediatric Aplastic Anemia and Refractory Cytopenia of Childhood: A Retrospective Single Institutional Analysis to Determine Outcomes and Histomorphological Predictors Blood. 124: 4382-4382. DOI: 10.1182/Blood.V124.21.4382.4382  0.294
2019 Williams DA. Pairing JAK with MEK for improved therapeutic efficiency in myeloproliferative disorders. The Journal of Clinical Investigation. 130. PMID 30829649 DOI: 10.1172/Jci127582  0.293
2003 Walmsley MJ, Ooi SK, Reynolds LF, Smith SH, Ruf S, Mathiot A, Vanes L, Williams DA, Cancro MP, Tybulewicz VL. Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. Science (New York, N.Y.). 302: 459-62. PMID 14564011 DOI: 10.1126/Science.1089709  0.293
2008 Van der Loo JC, Swaney W, Nordling D, Schambach A, Baum C, Williams DA, Reeves L, Malik P. Production of High Titer cGMP-Grade SIN Gamma-Retroviral Vectors by Transfection in a Closed System Bioreactor Blood. 112: 3539-3539. DOI: 10.1182/Blood.V112.11.3539.3539  0.293
1993 Keller D, Du X, Srour E, Hoffman R, Williams D. Interleukin-11 inhibits adipogenesis and stimulates myelopoiesis in human long-term marrow cultures Blood. 82: 1428-1435. DOI: 10.1182/Blood.V82.5.1428.Bloodjournal8251428  0.293
2005 Chandra S, Levran O, Jurickova I, Maas C, Kapur R, Schindler D, Henry R, Milton K, Batish SD, Cancelas JA, Hanenberg H, Auerbach AD, Williams DA. A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 976-84. PMID 16084127 DOI: 10.1016/J.Ymthe.2005.04.021  0.293
2000 Woods EJ, Liu J, Derrow CW, Smith FO, Williams DA, Critser JK. Osmometric and permeability characteristics of human placental/umbilical cord blood CD34+ cells and their application to cryopreservation Journal of Hematotherapy and Stem Cell Research. 9: 161-173. PMID 10813529 DOI: 10.1089/152581600319379  0.293
2003 Howard V, Myers LA, Williams DA, Wheeler G, Turner EV, Cunningham JM, Conley ME. Stem cell transplants for patients with X-linked agammaglobulinemia. Clinical Immunology (Orlando, Fla.). 107: 98-102. PMID 12763478 DOI: 10.1016/S1521-6616(03)00045-7  0.292
2012 Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Bolton E, Holyoake TL, Eaves CJ, Cerny-Reiterer S, ... ... Williams DA, et al. Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors. Blood. 119: 4253-63. PMID 22411871 DOI: 10.1182/Blood-2011-10-385658  0.292
1992 Gil KM, Abrams MR, Phillips G, Williams DA. Sickle cell disease pain: II. Predicting health care use and activity level at 9-month follow-up. Journal of Consulting and Clinical Psychology. 60: 267-273. DOI: 10.1037/0022-006X.60.2.267  0.292
2006 Yang L, Wang L, Geiger H, Cancelas JA, Williams DA, Zheng Y. Cdc42 Is Critical for Multi-Lineage Blood Cell Development from Hematopoietic Stem and Progenitor Cells. Blood. 108: 633-633. DOI: 10.1182/Blood.V108.11.633.633  0.291
2006 Li S, Hildeman DA, Grimes HL, Williams DA, Gu Y. T Cell Lymphopenia in Rhoh−/− Mice Results from Combined Defects of T Cell Migration and IL-7-Regulated Naïve T Cell Homeostasis. Blood. 108: 872-872. DOI: 10.1182/Blood.V108.11.872.872  0.291
1991 Matsui Y, Toksoz D, Nishikawa S, Nishikawa S, Williams D, Zsebo K, Hogan BL. Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture. Nature. 353: 750-2. PMID 1719421 DOI: 10.1038/353750A0  0.291
2016 Labenski V, Suerth JD, Barczak E, Heckl D, Levy C, Bernadin O, Charpentier E, Williams DA, Fehse B, Verhoeyen E, Schambach A. Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes. Biomaterials. 97: 97-109. PMID 27162078 DOI: 10.1016/J.Biomaterials.2016.04.019  0.291
2006 Yamada Y, Rothenberg ME, Lee AW, Akei HS, Brandt EB, Williams DA, Cancelas JA. The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease. Blood. 107: 4071-9. PMID 16418325 DOI: 10.1182/Blood-2005-08-3153  0.291
2017 Knoerl R, Yang J, Barton DL, Williams DA, Holden J, Krauss JC, Bridges C, Smith EML. Self-guided online cognitive behavioral strategies for chemotherapy-induced peripheral neuropathy (CIPN): A multicenter, single blind, randomized, wait-list controlled trial. Journal of Clinical Oncology. 35: e21710-e21710. DOI: 10.1200/Jco.2017.35.15_Suppl.E21710  0.29
2013 Henry NL, Harte S, Conlon AS, Griffith KA, Ramirez G, Hayden J, Smerage JB, Schott AF, Hayes DF, Williams DA, Clauw DA. Pain sensitivity and aromatase inhibitor (AI)-associated arthralgias (AIAA). Journal of Clinical Oncology. 31: 9615-9615. DOI: 10.1200/Jco.2013.31.15_Suppl.9615  0.289
2000 Croop J, Cooper R, Seshadri R, Fernandez C, Graves V, Kreissman S, Smith F, Cornetta K, Williams D, Abonour R. Large-scale mobilization and isolation of CD34+ cells from normal donors. Bone Marrow Transplantation. 26: 1271-1279. PMID 11223966 DOI: 10.1038/Sj.Bmt.1702720  0.289
2009 Williams DA. National institutes of health releases new guidelines on human stem cell research Molecular Therapy. 17: 1485-1486. PMID 19721416 DOI: 10.1038/Mt.2009.191  0.289
2019 Smith AR, Schiller GJ, Vercellotti GM, Kwiatkowski JL, Krishnamurti L, Esrick EB, Williams DA, Miller WP, Woolfson A, Walters MC. Preliminary Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent Beta Thalassemia Blood. 134: 3544-3544. DOI: 10.1182/Blood-2019-125743  0.288
2013 Troeger A, Williams DA. Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders. Experimental Cell Research. 319: 2375-83. PMID 23850828 DOI: 10.1016/J.Yexcr.2013.07.002  0.288
2011 Mizukawa B, Wei J, Shrestha M, Wunderlich M, Chou FS, Griesinger A, Harris CE, Kumar AR, Zheng Y, Williams DA, Mulloy JC. Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia. Blood. 118: 5235-45. PMID 21940819 DOI: 10.1182/Blood-2011-04-351817  0.288
2007 Sanchez-Aguilera A, Cancelas J, Williams DA. RhoH-Deficient Mice Show Altered B Cell Populations In Vivo. Blood. 110: 2307-2307. DOI: 10.1182/Blood.V110.11.2307.2307  0.288
2003 Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195  0.287
2010 Chae HD, Siefring JE, Hildeman DA, Gu Y, Williams DA. RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling. Plos One. 5: e13970. PMID 21103055 DOI: 10.1371/Journal.Pone.0013970  0.287
2007 Chae H, Siefring JE, Hildeman DA, Gu Y, Williams DA. RhoH Functions as an Adaptor Molecule for ZAP-70 in TCR Signaling Pathway. Blood. 110: 795-795. DOI: 10.1182/Blood.V110.11.795.795  0.286
2001 Chen J, Reeves L, Sanburn N, Croop J, Williams DA, Cornetta K. Packaging cell line DNA contamination of vector supernatants: implication for laboratory and clinical research. Virology. 282: 186-97. PMID 11259201 DOI: 10.1006/Viro.2001.0826  0.286
2017 Mehta PA, Davies SM, Leemhuis T, Myers K, Kernan NA, Prockop SE, Scaradavou A, O'Reilly RJ, Williams DA, Lehmann L, Guinan E, Margolis D, Baker KS, Lane A, Boulad F. Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study. Blood. 129: 2308-2315. PMID 28179273 DOI: 10.1182/Blood-2016-09-743112  0.286
2003 Giesecke T, Williams DA, Harris RE, Cupps TR, Tian X, Tian TX, Gracely RH, Clauw DJ. Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factors. Arthritis and Rheumatism. 48: 2916-22. PMID 14558098 DOI: 10.1002/Art.11272  0.286
2013 Keerthivasan G, Zhao B, Harris CE, Zhang L, Gao J, McElherne J, Yang J, Basiorka AA, Schipma M, Boultwood J, Verma A, List A, Williams DA, Ji P. Aberrant Overexpression Of CD14 In Granulocytes Sensitizes Innate Immune Response In mDia1 Heterozygous Myelodysplastic Syndromes Blood. 122: 1557-1557. DOI: 10.1182/Blood.V122.21.1557.1557  0.286
2006 Gu Y, Chae HD, Siefring JE, Jasti AC, Hildeman DA, Williams DA. RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development. Nature Immunology. 7: 1182-90. PMID 17028588 DOI: 10.1038/Ni1396  0.286
2004 Williams DA, Gendreau M, Hufford MR, Groner K, Gracely RH, Clauw DJ. Pain assessment in patients with fibromyalgia syndrome: a consideration of methods for clinical trials. The Clinical Journal of Pain. 20: 348-56. PMID 15322442 DOI: 10.1097/00002508-200409000-00010  0.285
2009 Singh TR, Bakker ST, Agarwal S, Jansen M, Grassman E, Godthelp BC, Ali AM, Du CH, Rooimans MA, Fan Q, Wahengbam K, Steltenpool J, Andreassen PR, Williams DA, Joenje H, et al. Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood. 114: 174-80. PMID 19423727 DOI: 10.1182/Blood-2009-02-207811  0.285
2014 Williams DA. Characterization of individuals with chronic pain: phenotyping approaches used in MAPP Molecular Pain. 10: O19. DOI: 10.1186/1744-8069-10-S1-O19  0.285
2005 Mehta PA, Ileri T, Harris RE, Williams DA, Auerbach AD, Smith FO, Mo J, Smolarek T, Kelly P, Davies SM. Tolerability of Chemotherapy for AML or MDS in Children with Fanconi Anemia. Blood. 106: 898-898. DOI: 10.1182/Blood.V106.11.898.898  0.285
2007 Williams DA. Of Mouse Models and Men. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 643. PMID 28192701 DOI: 10.1038/Sj.Mt.6300133  0.284
2007 Sejas DP, Rani R, Qiu Y, Zhang X, Fagerlie SR, Nakano H, Williams DA, Pang Q. Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 178: 5277-87. PMID 17404312 DOI: 10.4049/Jimmunol.178.8.5277  0.284
2016 Taylor AM, Phillips K, Patel KV, Turk DC, Dworkin RH, Beaton D, Clauw DJ, Gignac MA, Markman JD, Williams DA, Bujanover S, Burke LB, Carr DB, Choy EH, Conaghan PG, et al. Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations. Pain. 157: 1836-50. PMID 27058676 DOI: 10.1097/J.Pain.0000000000000577  0.284
1990 Gil KM, Williams DA, Keefe FJ, Beckham JC. The relationship of negative thoughts to pain and psychological distress Behavior Therapy. 21: 349-362. DOI: 10.1016/S0005-7894(05)80336-3  0.284
2015 Mehta PA, Davies SM, Myers KC, Leemhuis T, Williams DA, Lehmann LE, Guinan E, Margolis DA, Baker KS, Klein E, Boulad F. Chemotherapy-Only Preparative Regimen for Alternative Donor Hematopoietic Cell Transplantation for Patients with Fanconi Anemia (FA): Results of a Multi-Institutional Study Biology of Blood and Marrow Transplantation. 21: S104-S105. DOI: 10.1016/J.Bbmt.2014.11.126  0.284
2000 Li B, Yu H, Zheng W, Voll R, Na S, Roberts AW, Williams DA, Davis RJ, Ghosh S, Flavell RA. Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation. Science (New York, N.Y.). 288: 2219-22. PMID 10864872 DOI: 10.1126/Science.288.5474.2219  0.283
2017 Lumley MA, Schubiner H, Lockhart NA, Kidwell KM, Harte SE, Clauw DJ, Williams DA. Emotional awareness and expression therapy, cognitive-behavioral therapy, and education for fibromyalgia: a cluster-randomized controlled trial. Pain. PMID 28796118 DOI: 10.1097/J.Pain.0000000000001036  0.283
2011 Pai SY, Kim C, Williams DA. Rac GTPases in human diseases. Disease Markers. 29: 177-87. PMID 21178276 DOI: 10.3233/Dma-2010-0738  0.283
2017 Knoerl R, Smith EML, Barton DL, Williams DA, Holden JE, Krauss JC, LaVasseur B. Self-Guided Online Cognitive Behavioral Strategies for Chemotherapy-Induced Peripheral Neuropathy: a Multicenter, Pilot, Randomized, Wait-List Controlled Trial. The Journal of Pain : Official Journal of the American Pain Society. PMID 29229430 DOI: 10.1016/J.Jpain.2017.11.009  0.282
2016 Maixner W, Fillingim RB, Williams DA, Smith SB, Slade GD. Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification. The Journal of Pain : Official Journal of the American Pain Society. 17: T93-T107. PMID 27586833 DOI: 10.1016/J.Jpain.2016.06.002  0.282
2013 Tala I, Chen R, Hu T, Fitzpatrick ER, Williams DA, Whitehead IP. Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression. Leukemia. 27: 1080-9. PMID 23207522 DOI: 10.1038/Leu.2012.351  0.282
2020 Pulsipher MA, Lehmann LE, Bertuch AA, Sasa G, Olson T, Nakano T, Gilio A, Burroughs LM, Lipton JM, Huang JN, Dickerson K, Bertaina A, Zhuang C, Malsch M, Fleming M, ... ... Williams DA, et al. A study assessing the feasibility of randomization of pediatric and young adult patients between matched unrelated donor bone marrow transplantation and immune-suppressive therapy for newly diagnosed severe aplastic anemia: A joint pilot trial of the North American Pediatric Aplastic Anemia Consortium and the Pediatric Transplantation and Cellular Therapy Consortium. Pediatric Blood & Cancer. e28444. PMID 32776425 DOI: 10.1002/Pbc.28444  0.282
2003 Williams DA. Psychological and behavioural therapies in fibromyalgia and related syndromes Best Practice and Research: Clinical Rheumatology. 17: 649-665. PMID 12849717 DOI: 10.1016/S1521-6942(03)00034-2  0.282
1990 Keefe FJ, Caldwell DS, Williams DA, Gil KM, Mitchell D, Robertson C, Martinez S, Nunley J, Beckham JC, Helms M. Pain coping skills training in the management of osteoarthritic knee pain-II: Follow-up results Behavior Therapy. 21: 435-447. DOI: 10.1016/S0005-7894(05)80357-0  0.282
2012 McCarberg BH, Stanos S, Williams DA. Comprehensive chronic pain management: improving physical and psychological function (CME multimedia activity). The American Journal of Medicine. 125: S1. PMID 22624694 DOI: 10.1016/J.Amjmed.2011.10.004  0.281
1993 James LD, Thorn BE, Williams DA. Goal specification in cognitive-behavioral therapy for chronic headache pain Behavior Therapy. 24: 305-320. DOI: 10.1016/S0005-7894(05)80271-0  0.281
2012 Boulad F, Davies SM, Williams DA, Margolis DA, Klein EG, Lehmann LE, Duncan C, Guinan EC, Mehta PA. Chemotherapy-Only Preparative Regimen for T-Cell Depleted Hematopoietic Stem Cell Transplantation of Patients with Fanconi Anemia From Alternative Donors Blood. 120: 3471-3471. DOI: 10.1182/Blood.V120.21.3471.3471  0.281
2018 D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Chen AA, Gavillet M, Lawlor KE, Vince JE, Kelliher M, Hakem R, Pasparakis M, Williams DA, Ericsson M, Croker BA. Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl Blood. 132: 276-276. DOI: 10.1182/Blood-2018-99-110051  0.281
2001 Kapur R, Cooper R, Zhang L, Williams DA. Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways. Blood. 97: 1975-81. PMID 11264161 DOI: 10.1182/Blood.V97.7.1975  0.281
2019 Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, ... ... Williams DA, et al. Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study. Haematologica. PMID 30948484 DOI: 10.3324/Haematol.2018.206540  0.281
2002 Moritz T, Williams DA. Marrow protection - transduction of hematopoietic cells with drug resistance genes. Cytotherapy. 3: 67-84. PMID 12028830 DOI: 10.1080/14653240152584640  0.28
2005 Chae H, Lee KE, Jasti AC, Williams DA, Gu Y. Cross-Talk between Rho GTPases Regulates Actin Cytoskeleton and Chemotaxis of Hematopoietic Progenitor Cell. Blood. 106: 266-266. DOI: 10.1182/Blood.V106.11.266.266  0.28
2001 Ingram DA, Hiatt K, King AJ, Fisher L, Shivakumar R, Derstine C, Wenning MJ, Diaz B, Travers JB, Hood A, Marshall M, Williams DA, Clapp DW. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro. The Journal of Experimental Medicine. 194: 57-69. PMID 11435472 DOI: 10.1084/Jem.194.1.57  0.28
2016 Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Williams DA, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 29: 574-86. PMID 27070704 DOI: 10.1016/J.Ccell.2016.03.008  0.28
2014 Brendel C, Williams DA. Unexpected help: mTOR meets lentiviral vectors. Blood. 124: 832-3. PMID 25104861 DOI: 10.1182/Blood-2014-06-582411  0.279
2008 Thomas EK, Cancelas JA, Zheng Y, Williams DA. Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis. Leukemia. 22: 898-904. PMID 18354486 DOI: 10.1038/Leu.2008.71  0.279
2009 Williams DA, Clauw DJ. Understanding Fibromyalgia: Lessons from the Broader Pain Research Community Journal of Pain. 10: 777-791. PMID 19638325 DOI: 10.1016/J.Jpain.2009.06.001  0.279
2016 Reddy PN, Radu M, Xu K, Wood J, Harris CE, Chernoff J, Williams DA. p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix. Blood. 127: 1967-75. PMID 26932803 DOI: 10.1182/Blood-2016-01-693572  0.279
2018 Schrepf A, Williams DA, Gallop R, Naliboff B, Basu N, Kaplan C, Harper DE, Landis R, Clemens JQ, Strachan E, Griffith JW, Afari N, Hassett A, Pontari MA, Clauw DJ, et al. Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: a MAPP Research Network study. Pain. PMID 29863527 DOI: 10.1097/J.Pain.0000000000001299  0.279
2007 Chae HD, Lee KE, Williams DA, Gu Y. Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells. Blood. 111: 2597-605. PMID 18089848 DOI: 10.1182/Blood-2007-06-093237  0.278
2014 Keerthivasan G, Mei Y, Zhao B, Zhang L, Harris CE, Gao J, Basiorka AA, Schipma MJ, McElherne J, Yang J, Verma AK, Pellagatti A, Boultwood J, List AF, Williams DA, et al. Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS. Blood. 124: 780-90. PMID 24891322 DOI: 10.1182/Blood-2014-01-552463  0.278
2003 Chandra S, Kapur R, Chuzhanova N, Summey V, Prentice D, Barker J, Cooper DN, Williams DA. A rare complex DNA rearrangement in the murine Steel gene results in exon duplication and a lethal phenotype. Blood. 102: 3548-55. PMID 12881302 DOI: 10.1182/Blood-2003-05-1468  0.278
2011 Hassett AL, Williams DA. Non-pharmacological treatment of chronic widespread musculoskeletal pain. Best Practice & Research. Clinical Rheumatology. 25: 299-309. PMID 22094203 DOI: 10.1016/J.Berh.2011.01.005  0.277
2006 Harris RE, Gracely RH, McLean SA, Williams DA, Giesecke T, Petzke F, Sen A, Clauw DJ. Comparison of clinical and evoked pain measures in fibromyalgia. The Journal of Pain : Official Journal of the American Pain Society. 7: 521-7. PMID 16814691 DOI: 10.1016/J.Jpain.2006.01.455  0.277
2007 Milsom MD, Harris CE, Schambach A, Broun E, Jerabek-Willemsen M, Baum C, Moritz T, Margison G, Thomale J, Williams DA. Very High Expression of MGMT(P140K) Paradoxically Impairs Proliferation, In Vivo Selection and Protection of Transduced Hematopoietic Stem Cells. Blood. 110: 2588-2588. DOI: 10.1182/Blood.V110.11.2588.2588  0.277
2007 Rattmann I, Zhu D, Croce CM, Byrd JC, Gu Y, Moritz T, Williams DA. The Expression of the GTPase-Deficient, Hematopoietic-Specific RhoH GTPase Is Implicated in Development of Chronic Lymphocytic Leukemia (CLL). Blood. 110: 339-339. DOI: 10.1182/Blood.V110.11.339.339  0.277
2008 Williams DA. NIH recombinant DNA advisory committee continues to ponder adverse event associated with AAV gene therapy trial Molecular Therapy. 16: 427-428. PMID 18297091 DOI: 10.1038/Mt.2008.2  0.277
2012 Phillips K, Williams D, Hassett A, Morris M, Urquhart A, Hallstrom B, Clauw D, Brummett C. The prevalence and role of the central pain phenotype in patients undergoing knee or hip arthroplasty Osteoarthritis and Cartilage. 20: S254. DOI: 10.1016/J.Joca.2012.02.423  0.276
2014 Monif M, O'Brien TJ, Drummond KJ, Reid CA, Liubinas SV, Williams DA. P2X7 receptors are a potential novel target for anti-glioma therapies Journal of Inflammation (United Kingdom). 11. DOI: 10.1186/S12950-014-0025-4  0.276
2010 Hsu MC, Schubiner H, Lumley MA, Stracks JS, Clauw DJ, Williams DA. Sustained pain reduction through affective self-awareness in fibromyalgia: a randomized controlled trial. Journal of General Internal Medicine. 25: 1064-70. PMID 20532650 DOI: 10.1007/S11606-010-1418-6  0.276
2016 Williams DA, Kratz AL. Patient-Reported Outcomes and Fibromyalgia. Rheumatic Diseases Clinics of North America. 42: 317-32. PMID 27133492 DOI: 10.1016/J.Rdc.2016.01.009  0.276
2007 Williams DA, Park KM, Ambrose KR, Clauw DJ. Assessor Status Influences Pain Recall Journal of Pain. 8: 343-348. PMID 17223390 DOI: 10.1016/J.Jpain.2006.10.005  0.275
1995 Williams DA, Urban B, Keefe FJ, Shutty MS, France R. Cluster analyses of pain patients' responses to the SCL-90R. Pain. 61: 81-91. PMID 7644252 DOI: 10.1016/0304-3959(94)00165-B  0.275
1990 Keefe FJ, Crisson J, Urban BJ, Williams DA. Analyzing chronic low back pain: the relative contribution of pain coping strategies. Pain. 40: 293-301. PMID 2139204 DOI: 10.1016/0304-3959(90)91126-4  0.275
1998 Plehn K, Peterson RA, Williams DA. Anxiety sensitivity: Its relationship to functional status in patients with chronic pain Journal of Occupational Rehabilitation. 8: 213-222. DOI: 10.1023/A:1021330607652  0.275
2004 Giesecke T, Gracely RH, Grant MA, Nachemson A, Petzke F, Williams DA, Clauw DJ. Evidence of augmented central pain processing in idiopathic chronic low back pain. Arthritis and Rheumatism. 50: 613-23. PMID 14872506 DOI: 10.1002/Art.20063  0.275
2005 Yang L, Wang L, Cancelas JA, Williams DA, Zheng Y. A Critical Role of the Rho Family GTPase Cdc42 in Hematopoietic Stem Cell Mobilization, Homing, Engraftment and Differentiation. Blood. 106: 269-269. DOI: 10.1182/Blood.V106.11.269.269  0.275
2019 Boehnke KF, Scott JR, Litinas E, Sisley S, Williams DA, Clauw DJ. High frequency medical cannabis use is associated with worse pain among individuals with chronic pain. The Journal of Pain : Official Journal of the American Pain Society. PMID 31560957 DOI: 10.1016/J.Jpain.2019.09.006  0.274
2005 Ghiaur G, Ferkowicz MJ, Bailey J, Yoder MC, Williams DA. Rac1 Regulates Migration of Yolk Sac Hematopoietic Progenitors into the Blood, a Process Essential for Subsequent Seeding of Fetal Liver Hematopoiesis. Blood. 106: 518-518. DOI: 10.1182/Blood.V106.11.518.518  0.274
1990 Keefe FJ, Williams DA. A comparison of coping strategies in chronic pain patients in different age groups. Journal of Gerontology. 45: P161-5. PMID 2365972 DOI: 10.1093/Geronj/45.4.P161  0.274
2007 Yamada Y, Cancelas JA, Brandt EB, Sanchez-Aguilera A, McBride M, Al-Moamen NJ, Finkelman F, Williams DA, Rothenberg ME. FIP1L1/PDGFRa Synergizes with SCF/c-Kit Signaling To Induce Systemic Mastocytosis in a Chronic Eosinophilic Leukemia Murine Model Blood. 110: 1540-1540. DOI: 10.1182/Blood.V110.11.1540.1540  0.274
1999 Pollok KE, van der Loo JC, Cooper RJ, Kennedy L, Williams DA. Costimulation of transduced T lymphocytes via T cell receptor-CD3 complex and CD28 leads to increased transcription of integrated retrovirus. Human Gene Therapy. 10: 2221-36. PMID 10498253 DOI: 10.1089/10430349950017202  0.274
2006 Giesecke T, Gracely RH, Clauw DJ, Nachemson A, Dück MH, Sabatowski R, Gerbershagen HJ, Williams DA, Petzke F. [Central pain processing in chronic low back pain. Evidence for reduced pain inhibition]. Schmerz (Berlin, Germany). 20: 411-4, 416-7. PMID 16586062 DOI: 10.1007/S00482-006-0473-8  0.273
1980 Williams DA, Lessard J, Boxer LA, Rein D, Baehner RL. Metabolic and structural requirements for concanavalin A capping in phagocytic cells. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 162: 34-7. PMID 504238 DOI: 10.3181/00379727-162-40613  0.273
2005 Harris RE, Williams DA, McLean SA, Sen A, Hufford M, Gendreau RM, Gracely RH, Clauw DJ. Characterization and consequences of pain variability in individuals with fibromyalgia. Arthritis and Rheumatism. 52: 3670-4. PMID 16258905 DOI: 10.1002/Art.21407  0.273
2020 Bellomo T, Schrepf A, Kruger GH, Lumley MA, Schubiner H, Clauw DJ, Williams DA, Harte SE. Pressure Pain Tolerance Predicts the Success of Emotional Awareness and Expression Therapy in Patients with Fibromyalgia. The Clinical Journal of Pain. PMID 32271184 DOI: 10.1097/Ajp.0000000000000829  0.273
2007 Geisser ME, Gracely RH, Giesecke T, Petzke FW, Williams DA, Clauw DJ. The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndrome. European Journal of Pain (London, England). 11: 202-7. PMID 16546424 DOI: 10.1016/J.Ejpain.2006.02.001  0.273
2000 Petrou S, Bowser DN, Nicholls RA, Panchal RG, Smart ML, Reilly AM, Williams DA. Genetically targeted calcium sensors enhance the study of organelle function in living cells. Clinical and Experimental Pharmacology & Physiology. 27: 738-44. PMID 10972543 DOI: 10.1046/J.1440-1681.2000.03327.X  0.273
2012 Murphy SL, Phillips K, Williams DA, Clauw DJ. The role of the central nervous system in osteoarthritis pain and implications for rehabilitation. Current Rheumatology Reports. 14: 576-82. PMID 22879060 DOI: 10.1007/S11926-012-0285-Z  0.272
1992 Williams DA, Keefe FJ. Pain beliefs and the use of cognitive-behavioral coping strategies. Pain. 46: 185-90. PMID 1749641 DOI: 10.1016/0304-3959(91)90074-8  0.272
1990 Keefe FJ, Caldwell DS, Williams DA, Gil KM, Mitchell D, Robertson C, Martinez S, Nunley J, Beckham JC, Crisson JE, Helms M. Pain coping skills training in the management of osteoarthritic knee pain: A comparative study Behavior Therapy. 21: 49-62. DOI: 10.1016/S0005-7894(05)80188-1  0.272
2013 Hofmann I, Kierstead D, Krasker J, Campagna D, Schmitz-Abe K, Markianos K, Lee MA, Sieff CA, Agarwal S, Clark JJ, Jeng M, Loh ML, Shereck E, Williams DA, Fleming MD. GATA2 Mutations In Pediatric Myelodysplastic Syndromes and Bone Marrow Failure Blood. 122: 1520-1520. DOI: 10.1182/Blood.V122.21.1520.1520  0.272
2007 Goettig S, Pinter A, Deak E, Stroebele C, Seifried E, Cancelas J, Williams DA, Gille J, Henschler R. Rac GTPases Modulate Migration of Hematopoietic Progenitor Cells in an SDF-1α Dependent Manner in a Tumor Model. Blood. 110: 222-222. DOI: 10.1182/Blood.V110.11.222.222  0.272
2017 Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Chawla A, Castillo P, Wang W, Gillio A, Nalepa G, Kurre P, Bennett CM, Hanna R, Gamper C, Kupfer GM, Rothman JA, ... ... Williams DA, et al. Outcomes of Immunosuppressive Therapy for Pediatric Aplastic Anemia: A North American Pediatric Aplastic Anemia Consortium (NAPAAC) Study Blood. 130: 1168-1168. DOI: 10.1182/Blood.V130.Suppl_1.1168.1168  0.272
1992 Keefe FJ, Caldwell DS, Martinez S, Nunley J, Beckham J, Williams DA. Analyzing pain in rheumatoid arthritis patients. Pain coping strategies in patients who have had knee replacement surgery. Pain. 46: 153-60. PMID 1749638 DOI: 10.1016/0304-3959(91)90070-E  0.271
2004 Williams D, Bennett K, Feely J. Prescribing for osteoporosis following the use of inhaled and oral glucocorticoids in general practice British Journal of Clinical Pharmacology. 58: 665-672. PMID 15563364 DOI: 10.1111/J.1365-2125.2004.02218.X  0.271
2007 Williams DA. NIH decides against continuing NGVLs in their current form Molecular Therapy. 15: 1223. PMID 17579591 DOI: 10.1038/Sj.Mt.6300226  0.271
2005 Petzke F, Harris RE, Williams DA, Clauw DJ, Gracely RH. Differences in unpleasantness induced by experimental pressure pain between patients with fibromyalgia and healthy controls. European Journal of Pain (London, England). 9: 325-35. PMID 15862482 DOI: 10.1016/J.Ejpain.2004.09.001  0.271
2009 Milsom MD, Schiedlmeier B, Bailey J, Kim MO, Li D, Jansen M, Ali AM, Kirby M, Baum C, Fairbairn LJ, Williams DA. Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. Blood. 113: 5111-20. PMID 19270262 DOI: 10.1182/Blood-2008-09-180224  0.271
2003 Williams DA, Baum C. Gene Therapy--New Challenges Ahead Science. 302: 400-401. PMID 14563994 DOI: 10.1126/Science.1091258  0.27
2009 Williams DA, Schilling S. Advances in the assessment of fibromyalgia. Rheumatic Diseases Clinics of North America. 35: 339-57. PMID 19647147 DOI: 10.1016/J.Rdc.2009.05.007  0.27
2010 Geisser ME, Clauw DJ, Strand V, Gendreau RM, Palmer R, Williams DA. Contributions of change in clinical status parameters to Patient Global Impression of Change (PGIC) scores among persons with fibromyalgia treated with milnacipran. Pain. 149: 373-8. PMID 20332060 DOI: 10.1016/J.Pain.2010.02.043  0.27
2011 Williams DA, Arnold LM. Measures of fibromyalgia: Fibromyalgia Impact Questionnaire (FIQ), Brief Pain Inventory (BPI), Multidimensional Fatigue Inventory (MFI-20), Medical Outcomes Study (MOS) Sleep Scale, and Multiple Ability Self-Report Questionnaire (MASQ). Arthritis Care & Research. 63: S86-97. PMID 22588773 DOI: 10.1002/Acr.20531  0.27
2018 D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Wang S, Chen AA, Gavillet M, Al-Obeidi A, Lawlor KE, Vince JE, Kelliher MA, Hakem R, Pasparakis M, Williams DA, Ericsson M, et al. The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils. Science Signaling. 11. PMID 30181240 DOI: 10.1126/Scisignal.Aao1716  0.269
2011 Wong WS, Williams DA, Mak KH, Fielding R. Assessing attitudes toward and beliefs about pain among Chinese patients with chronic pain: Validity and reliability of the Chinese version of the Pain Beliefs and Perceptions Inventory (ChPBPI) Journal of Pain and Symptom Management. 42: 308-318. PMID 21402462 DOI: 10.1016/J.Jpainsymman.2010.10.263  0.269
2005 McLean SA, Williams DA, Harris RE, Kop WJ, Groner KH, Ambrose K, Lyden AK, Gracely RH, Crofford LJ, Geisser ME, Sen A, Biswas P, Clauw DJ. Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia. Arthritis and Rheumatism. 52: 3660-9. PMID 16258904 DOI: 10.1002/Art.21372  0.269
2006 McLean SA, Williams DA, Stein PK, Harris RE, Lyden AK, Whalen G, Park KM, Liberzon I, Sen A, Gracely RH, Baraniuk JN, Clauw DJ. Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2776-82. PMID 16936702 DOI: 10.1038/Sj.Npp.1301200  0.269
1999 Clauw DJ, Williams D, Lauerman W, Dahlman M, Aslami A, Nachemson AL, Kobrine AI, Wiesel SW. Pain sensitivity as a correlate of clinical status in individuals with chronic low back pain. Spine. 24: 2035-41. PMID 10528381 DOI: 10.1097/00007632-199910010-00013  0.269
2005 Kop WJ, Lyden A, Berlin AA, Ambrose K, Olsen C, Gracely RH, Williams DA, Clauw DJ. Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome. Arthritis and Rheumatism. 52: 296-303. PMID 15641057 DOI: 10.1002/Art.20779  0.269
2016 Brummett CM, Bakshi RR, Goesling J, Leung D, Moser SE, Zollars JW, Williams DA, Clauw DJ, Hassett AL. Preliminary validation of the Michigan Body Map. Pain. 157: 1205-12. PMID 26835782 DOI: 10.1097/J.Pain.0000000000000506  0.269
2012 Roth RS, Geisser ME, Williams DA. Interventional pain medicine: retreat from the biopsychosocial model of pain. Translational Behavioral Medicine. 2: 106-16. PMID 24073101 DOI: 10.1007/S13142-011-0090-7  0.269
2007 Williams DA. RAC reviews serious adverse event associated with AAV therapy trial Molecular Therapy. 15: 2053-2054. PMID 18026178 DOI: 10.1038/Sj.Mt.6300352  0.269
1989 Keefe FJ, Williams DA. New directions in pain assessment and treatment Clinical Psychology Review. 9: 549-568. DOI: 10.1016/0272-7358(89)90011-1  0.269
1994 Williams DA, Robinson ME, Geisser ME. Pain beliefs: assessment and utility Pain. 59: 71-78. PMID 7854805 DOI: 10.1016/0304-3959(94)90049-3  0.269
1990 Gil KM, Ginsberg B, Muir M, Sykes D, Williams DA. Patient-controlled analgesia in postoperative pain: The relation of psychological factors to pain and analgesic use Clinical Journal of Pain. 6: 137-142. PMID 2135004 DOI: 10.1097/00002508-199006000-00012  0.269
2011 Glass JM, Williams DA, Fernandez-Sanchez ML, Kairys A, Barjola P, Heitzeg MM, Clauw DJ, Schmidt-Wilcke T. Executive function in chronic pain patients and healthy controls: different cortical activation during response inhibition in fibromyalgia. The Journal of Pain : Official Journal of the American Pain Society. 12: 1219-29. PMID 21945593 DOI: 10.1016/J.Jpain.2011.06.007  0.268
2019 Kim S, Whibley D, Williams DA, Kratz AL. Pain acceptance in people with chronic pain and spinal cord injury: Daily fluctuation and impacts on physical and psychosocial functioning. The Journal of Pain : Official Journal of the American Pain Society. PMID 31520733 DOI: 10.1016/J.Jpain.2019.08.014  0.268
2012 van der Loo JC, Swaney WP, Grassman E, Terwilliger A, Higashimoto T, Schambach A, Baum C, Thrasher AJ, Williams DA, Nordling DL, Reeves L, Malik P. Scale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfection. Gene Therapy. 19: 246-54. PMID 21753795 DOI: 10.1038/Gt.2011.102  0.268
2014 Henry NL, Conlon A, Kidwell KM, Griffith K, Smerage JB, Schott AF, Hayes DF, Williams DA, Clauw DJ, Harte SE. Effect of estrogen depletion on pain sensitivity in aromatase inhibitor-treated women with early-stage breast cancer. The Journal of Pain : Official Journal of the American Pain Society. 15: 468-75. PMID 24462504 DOI: 10.1016/J.Jpain.2014.01.487  0.268
2019 Wenske B, Marischen L, Welzenbach J, Heimbach A, Hoffmann P, Corbacioglu S, Williams DA, Troeger A. Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells Blood. 134: 2754-2754. DOI: 10.1182/Blood-2019-128835  0.267
1996 Liu Q, Du XX, Schindel DT, Yang ZX, Rescorla FJ, Williams DA, Grosfeld JL. Trophic effects of interleukin-11 in rats with experimental short bowel syndrome. Journal of Pediatric Surgery. 31: 1047-50; discussion . PMID 8863231 DOI: 10.1016/S0022-3468(96)90084-6  0.267
2006 Williams DA, Croop J, Kelly P. Gene therapy in the treatment of Fanconi anemia, a progressive bone marrow failure syndrome. Current Opinion in Molecular Therapeutics. 7: 461-6. PMID 16248281  0.267
2007 Mehta PA, Ileri T, Harris RE, Williams DA, Mo J, Smolarek T, Auerbach AD, Kelly P, Davies SM. Chemotherapy for myeloid malignancy in children with Fanconi anemia. Pediatric Blood & Cancer. 48: 668-72. PMID 16609946 DOI: 10.1002/Pbc.20843  0.267
2014 Hacein-Bey-Abina S, Pai SY, Gaspar HB, Armant M, Berry CC, Blanche S, Bleesing J, Blondeau J, de Boer H, Buckland KF, Caccavelli L, Cros G, De Oliveira S, Fernández KS, Guo D, ... ... Williams DA, et al. A modified γ-retrovirus vector for X-linked severe combined immunodeficiency. The New England Journal of Medicine. 371: 1407-17. PMID 25295500 DOI: 10.1056/Nejmoa1404588  0.267
2007 Williams DA. AAV and Insertional Mutagenesis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1737. PMID 28182914 DOI: 10.1038/Sj.Mt.6300301  0.267
2008 Williams DA. Progress reported in two studies of clinical gene transfer into the retina Molecular Therapy. 16: 1181. PMID 18574492 DOI: 10.1038/Mt.2008.123  0.267
2014 Renella R, Schlehe JS, Selkoe DJ, Williams DA, LaVoie MJ. Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes. American Journal of Hematology. 89: 974-7. PMID 25043722 DOI: 10.1002/Ajh.23796  0.267
2006 Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, Joiner CH, Williams DA, Zheng Y. Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood. 108: 3637-45. PMID 16882712 DOI: 10.1182/Blood-2006-03-005942  0.266
2005 Fulkerson PC, Zhu H, Williams DA, Zimmermann N, Rothenberg ME. CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism. Blood. 106: 436-43. PMID 15802529 DOI: 10.1182/Blood-2005-02-0489  0.265
2017 Lai HH, Jemielita T, Sutcliffe S, Bradley CS, Naliboff B, Williams DA, Gereau RW, Kreder K, Clemens JQ, Rodriguez LV, Krieger JN, Farrar JT, Robinson N, Landis JR. Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study. The Journal of Urology. PMID 28373134 DOI: 10.1016/J.Juro.2017.03.132  0.265
2018 Park HH, Triboulet R, Bentler M, Guda S, Du P, Xu H, Gregory RI, Brendel C, Williams DA. DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAs. Molecular Therapy. Nucleic Acids. 12: 591-599. PMID 30195795 DOI: 10.1016/J.Omtn.2018.07.002  0.264
2002 Hanenberg H, Batish SD, Pollok KE, Vieten L, Verlander PC, Leurs C, Cooper RJ, Göttsche K, Haneline L, Clapp DW, Lobitz S, Williams DA, Auerbach AD. Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool. Experimental Hematology. 30: 410-20. PMID 12031647 DOI: 10.1016/S0301-472X(02)00782-8  0.264
1989 Williams DA, Thorn BE. An empirical assessment of pain beliefs. Pain. 36: 351-8. PMID 2710564 DOI: 10.1016/0304-3959(89)90095-X  0.264
2004 Williams DA, Farrell MJ, Cunningham J, Gracely RH, Ambrose K, Cupps T, Mohan N, Clauw DJ. Knee pain and radiographic osteoarthritis interact in the prediction of levels of self-reported disability. Arthritis and Rheumatism. 51: 558-61. PMID 15334427 DOI: 10.1002/Art.20537  0.264
2004 Gracely RH, Geisser ME, Giesecke T, Grant MA, Petzke F, Williams DA, Clauw DJ. Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain : a Journal of Neurology. 127: 835-43. PMID 14960499 DOI: 10.1093/Brain/Awh098  0.264
2005 Harris RE, Tian X, Williams DA, Tian TX, Cupps TR, Petzke F, Groner KH, Biswas P, Gracely RH, Clauw DJ. Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequency. Journal of Alternative and Complementary Medicine (New York, N.Y.). 11: 663-71. PMID 16131290 DOI: 10.1089/Acm.2005.11.663  0.264
2013 Henry N, Kidwell K, Hayes D, Storniolo A, Flockhart D, Stearns V, Clauw D, Williams D. Abstract S3-02: Associations between baseline patient-reported symptoms and discontinuation of adjuvant aromatase inhibitor (AI) therapy Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-S3-02  0.263
2004 Chandra S, Levran O, Jurickova I, Mass C, Kapur R, Hanenberg H, Auerbach AD, Williams DA. A Rapid Method for Retroviral Mediated Subtyping of Complementation Group in Fanconi Anemia Patients. Blood. 104: 5261-5261. DOI: 10.1182/Blood.V104.11.5261.5261  0.263
2019 Boehnke KF, Scott JR, Litinas E, Sisley S, Williams DA, Clauw DJ. Pills to pot: observational analyses of cannabis substitution among medical cannabis users with chronic pain. The Journal of Pain : Official Journal of the American Pain Society. PMID 30690169 DOI: 10.1016/J.Jpain.2019.01.010  0.263
2015 Gavillet M, Martinod K, Renella R, Harris C, Shapiro NI, Wagner DD, Williams DA. Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples. American Journal of Hematology. 90: 1155-8. PMID 26347989 DOI: 10.1002/Ajh.24185  0.263
2002 Worthington RA, Smart ML, Gu BJ, Williams DA, Petrou S, Wiley JS, Barden JA. Point mutations confer loss of ATP-induced human P2X(7) receptor function. Febs Letters. 512: 43-6. PMID 11852049 DOI: 10.1016/S0014-5793(01)03311-7  0.263
2010 Williams DA, Thrasher AJ, Baum C. Transatlantic consortium spotlights need for changes in gene therapy trials Molecular Therapy. 18: 1892. PMID 21042294 DOI: 10.1038/Mt.2010.227  0.262
2014 Gavillet M, Martinod K, Wagner DD, Williams DA. The Role of Rac and Pak in Neutrophil Histone Hypercitrullination and Neutrophil Extracellular Traps Formation Blood. 124: 462-462. DOI: 10.1182/Blood.V124.21.462.462  0.262
2002 Clauw DJ, Williams DA. Relationship between stress and pain in work-related upper extremity disorders: the hidden role of chronic multisymptom illnesses. American Journal of Industrial Medicine. 41: 370-82. PMID 12071490 DOI: 10.1002/Ajim.10068  0.262
2020 Afari N, Buchwald D, Clauw D, Hong B, Hou X, Krieger JN, Mullins C, Stephens-Shields AJ, Gasperi M, Williams DA. A MAPP Network Case-control Study of Urological Chronic Pelvic Pain Compared With Nonurological Pain Conditions. The Clinical Journal of Pain. 36: 8-15. PMID 31794439 DOI: 10.1097/Ajp.0000000000000769  0.262
2018 McKernan LC, Johnson BN, Reynolds WS, Williams DA, Cheavens JS, Dmochowski RR, Crofford LJ. Posttraumatic stress disorder in interstitial cystitis/bladder pain syndrome: Relationship to patient phenotype and clinical practice implications. Neurourology and Urodynamics. PMID 30350890 DOI: 10.1002/Nau.23861  0.262
2008 Williams DA. Sleeping beauty vector system moves toward human trials in the United States Molecular Therapy. 16: 1515-1516. PMID 18725873 DOI: 10.1038/Mt.2008.169  0.262
2011 Mease PJ, Clauw DJ, Christensen R, Crofford LJ, Gendreau RM, Martin SA, Simon LS, Strand V, Williams DA, Arnold LM. Toward development of a fibromyalgia responder index and disease activity score: OMERACT module update. The Journal of Rheumatology. 38: 1487-95. PMID 21724721 DOI: 10.3899/Jrheum.110277  0.262
1995 Pollock JD, Williams DA, Gifford MA, Li LL, Du X, Fisherman J, Orkin SH, Doerschuk CM, Dinauer MC. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nature Genetics. 9: 202-9. PMID 7719350 DOI: 10.1038/Ng0295-202  0.262
2016 Murphy SL, Kratz AL, Kidwell K, Lyden AK, Geisser ME, Williams DA. Brief time-based activity pacing instruction as a singular behavioral intervention was not effective in participants with symptomatic osteoarthritis. Pain. 157: 1563-73. PMID 26963847 DOI: 10.1097/J.Pain.0000000000000549  0.261
2003 Smart ML, Gu B, Panchal RG, Wiley J, Cromer B, Williams DA, Petrou S. P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. The Journal of Biological Chemistry. 278: 8853-60. PMID 12496266 DOI: 10.1074/Jbc.M211094200  0.261
1998 Hansen WK, Deutsch WA, Yacoub A, Xu Y, Williams DA, Kelley MR. Creation of a fully functional human chimeric DNA repair protein. Combining O6-methylguanine DNA methyltransferase (MGMT) and AP endonuclease (APE/redox effector factor 1 (Ref 1)) DNA repair proteins. The Journal of Biological Chemistry. 273: 756-62. PMID 9422728 DOI: 10.1074/Jbc.273.2.756  0.261
1993 Williams DA. Mechanisms of calcium release and propagation in cardiac cells. Do studies with confocal microscopy add to our understanding? Cell Calcium. 14: 724-735. PMID 8131189 DOI: 10.1016/0143-4160(93)90098-Q  0.261
1995 Miyazawa K, Williams D, Gotoh A, Nishimaki J, Broxmeyer H, Toyama K. Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form Blood. 85: 641-649. DOI: 10.1182/Blood.V85.3.641.Bloodjournal853641  0.261
2005 Giesecke T, Gracely RH, Williams DA, Geisser ME, Petzke FW, Clauw DJ. The relationship between depression, clinical pain, and experimental pain in a chronic pain cohort. Arthritis and Rheumatism. 52: 1577-84. PMID 15880832 DOI: 10.1002/Art.21008  0.26
2008 Milsom MD, Schiedlmeier B, Bailey J, Ali A, Kim M, Baum C, Jansen M, Williams DA. Ectopic HOXB4 Overcomes the Inhibitory Effect of TNFα on Hematopoietic Stem and Progenitor Cells in a Murine Fanconi Anemia Model. Blood. 112: 2041-2041. DOI: 10.1182/Blood.V112.11.2041.2041  0.26
2020 Clemens JQ, Kutch JJ, Mayer EA, Naliboff BD, Rodriguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Clauw DJ, Harte SE, Schrepf AD, Williams DA, Andriole GL, Lai HH, Buchwald D, et al. The Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS). Neurourology and Urodynamics. PMID 32578257 DOI: 10.1002/Nau.24423  0.26
2015 Hassett AL, Clauw DJ, Williams DA. Premature Aging in Fibromyalgia. Current Aging Science. 8: 178-85. PMID 26212052 DOI: 10.2174/1874609808666150727112214  0.26
2007 Williams DA. A new mechanism of leukemia drug resistance? New England Journal of Medicine. 357: 77-78. PMID 17611211 DOI: 10.1056/Nejmcibr072412  0.26
2001 Schmidt M, Hoffmann G, Wissler M, Lemke N, Müssig A, Glimm H, Williams DA, Ragg S, Hesemann CU, von Kalle C. Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples. Human Gene Therapy. 12: 743-9. PMID 11339891 DOI: 10.1089/104303401750148649  0.26
2016 Lumley M, Schubiner H, Clauw D, Lockhart N, Kidwell K, Williams D. (509) The PAST-FM (Pain and Stress Treatment for Fibromyalgia) randomized, controlled trial: main effects of emotional awareness and expression and cognitive-behavioral therapies. The Journal of Pain : Official Journal of the American Pain Society. 17: S102. PMID 28162316 DOI: 10.1016/J.Jpain.2016.01.316  0.26
2018 Schrepf A, Naliboff B, Williams DA, Stephens-Shields AJ, Landis JR, Gupta A, Mayer E, Rodriguez LV, Lai H, Luo Y, Bradley C, Kreder K, Lutgendorf SK. Adverse Childhood Experiences and Symptoms of Urologic Chronic Pelvic Pain Syndrome: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Study. Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine. 52: 865-877. PMID 30212850 DOI: 10.1093/Abm/Kax060  0.26
2012 Rini C, Williams DA, Broderick JE, Keefe FJ. Meeting them where they are: Using the Internet to deliver behavioral medicine interventions for pain. Translational Behavioral Medicine. 2: 82-92. PMID 22924084 DOI: 10.1007/S13142-011-0107-2  0.26
1998 Dy LC, Pei Y, Barber LA, Johnson C, Murphy RC, Nguyen T, Fertel RH, Kelley SW, Williams DA, Travers JB. Platelet-activating factor receptor activation induces both cytokine and cyclooxygenase biosynthesis in human epidermal cells Journal of Dermatological Science. 16: S180. DOI: 10.1016/S0923-1811(98)84078-4  0.26
2019 Higgins DM, Buta E, Williams DA, Halat A, Bair MJ, Heapy AA, Krein SL, Rajeevan H, Rosen MI, Kerns RD. Internet-based pain self-management for veterans: Feasibility and preliminary efficacy of the Pain EASE program. Pain Practice : the Official Journal of World Institute of Pain. PMID 31778281 DOI: 10.1111/Papr.12861  0.26
2012 Hassett AL, Epel E, Clauw DJ, Harris RE, Harte SE, Kairys A, Buyske S, Williams DA. Pain is associated with short leukocyte telomere length in women with fibromyalgia. The Journal of Pain : Official Journal of the American Pain Society. 13: 959-69. PMID 23031395 DOI: 10.1016/J.Jpain.2012.07.003  0.26
2010 Williams DA, Kuper D, Segar M, Mohan N, Sheth M, Clauw DJ. Internet-enhanced management of fibromyalgia: a randomized controlled trial. Pain. 151: 694-702. PMID 20855168 DOI: 10.1016/J.Pain.2010.08.034  0.26
2003 Kreklau EL, Pollok KE, Bailey BJ, Liu N, Hartwell JR, Williams DA, Erickson LC. Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea. Molecular Cancer Therapeutics. 2: 1321-9. PMID 14707273  0.259
2011 Williams DA. Web-based behavioral interventions for the management of chronic pain. Current Rheumatology Reports. 13: 543-9. PMID 21913061 DOI: 10.1007/S11926-011-0212-8  0.259
2011 Strober BE, Crowley JJ, Yamauchi PS, Olds M, Williams DA. Efficacy and safety results from a phase III, randomized controlled trial comparing the safety and efficacy of briakinumab with etanercept and placebo in patients with moderate to severe chronic plaque psoriasis. The British Journal of Dermatology. 165: 661-8. PMID 21574984 DOI: 10.1111/J.1365-2133.2011.10419.X  0.259
2014 Kidwell KM, Harte SE, Hayes DF, Storniolo AM, Carpenter J, Flockhart DA, Stearns V, Clauw DJ, Williams DA, Henry NL. Patient-reported symptoms and discontinuation of adjuvant aromatase inhibitor therapy. Cancer. 120: 2403-11. PMID 24802413 DOI: 10.1002/Cncr.28756  0.259
2015 Kimball AB, Sobell JM, Zouboulis CC, Gu Y, Williams DA, Sundaram M, Teixeira HD, Jemec GB. HiSCR (Hidradenitis Suppurativa Clinical Response): a novel clinical endpoint to evaluate therapeutic outcomes in patients with hidradenitis suppurativa from the placebo-controlled portion of a phase 2 adalimumab study. Journal of the European Academy of Dermatology and Venereology : Jeadv. PMID 26201313 DOI: 10.1111/Jdv.13216  0.259
1999 Minamikawa T, Williams DA, Bowser DN, Nagley P. Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells. Experimental Cell Research. 246: 26-37. PMID 9882512 DOI: 10.1006/Excr.1998.4290  0.258
2018 Clemens JQ, Stephens-Shields A, Naliboff BD, Lai HH, Rodriguez L, Krieger JN, Williams DA, Kusek JW, Landis JR. Correlates of Health-Care Seeking Activities in Patients with Urological Chronic Pelvic Pain Syndromes: Findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Cohort. The Journal of Urology. PMID 29307682 DOI: 10.1016/J.Juro.2017.12.055  0.258
2016 Reed BD, Plegue MA, Williams DA, Sen A. Presence of Spontaneous Pain and Comorbid Pain Conditions Identifies Vulvodynia Subgroups. Journal of Lower Genital Tract Disease. 20: 57-63. PMID 26704330 DOI: 10.1097/Lgt.0000000000000166  0.258
2003 Neff T, Horn PA, Peterson LJ, Thomasson BM, Thompson J, Williams DA, Schmidt M, Georges GE, von Kalle C, Kiem HP. Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model. The Journal of Clinical Investigation. 112: 1581-8. PMID 14617759 DOI: 10.1172/JCI18782  0.258
2009 Choy EH, Arnold LM, Clauw DJ, Crofford LJ, Glass JM, Simon LS, Martin SA, Strand CV, Williams DA, Mease PJ. Content and criterion validity of the preliminary core dataset for clinical trials in fibromyalgia syndrome. The Journal of Rheumatology. 36: 2330-4. PMID 19820222 DOI: 10.3899/Jrheum.090368  0.257
1988 Fay FS, Williams DA, Kargacin G, Tucker RW, Scanlon M. Role of local [Ca+2] in the control of cell function. Advances in Experimental Medicine and Biology. 232: 213-9. PMID 3063079 DOI: 10.1007/978-1-4757-0007-7_23  0.257
2014 Nguyen RH, Turner RM, Sieling J, Williams DA, Hodges JS, Harlow BL. Feasibility of collecting vulvar pain variability and its correlates using prospective collection with smartphones. Pain Research and Treatment. 2014: 659863. PMID 25006458 DOI: 10.1155/2014/659863  0.257
2019 Liu M, Degner J, Georgantas RW, Nader A, Mostafa NM, Teixeira HD, Williams DA, Kirsner RS, Nichols AJ, Davis JW, Waring JF. A GENETIC VARIANT IN THE BCL2 GENE ASSOCIATES WITH ADALIMUMAB RESPONSE IN HIDRADENITIS SUPPURATIVA CLINICAL TRIALS AND REGULATES EXPRESSION OF BCL2. The Journal of Investigative Dermatology. PMID 31465739 DOI: 10.1016/J.Jid.2019.06.152  0.257
2004 Krishnan N, Bailey JR, Summey-Harner V, Brunstein C, Verfaillie CM, Williams DA. Rhogtpase RAC2 Is Required for In Vivo Transformation Activity by P210 Bcr-Abl Fusion Oncogene. Blood. 104: 717-717. DOI: 10.1182/Blood.V104.11.717.717  0.257
2011 Murphy SL, Lyden AK, Phillips K, Clauw DJ, Williams DA. Subgroups of older adults with osteoarthritis based upon differing comorbid symptom presentations and potential underlying pain mechanisms. Arthritis Research & Therapy. 13: R135. PMID 21864381 DOI: 10.1186/Ar3449  0.256
1986 Williams DA, Fay FS. Calcium transients and resting levels in isolated smooth muscle cells as monitored with quin 2. The American Journal of Physiology. 250: C779-91. PMID 3085513 DOI: 10.1152/Ajpcell.1986.250.5.C779  0.256
1992 Gil KM, Ginsberg B, Muir M, Sullivan F, Williams DA. Patient Controlled Analgesia The Clinical Journal of Pain. 8: 215-221. DOI: 10.1097/00002508-199209000-00005  0.256
2020 Blauvelt A, Leonardi CL, Gooderham M, Papp KA, Philipp S, Wu JJ, Igarashi A, Flack M, Geng Z, Wu T, Camez A, Williams D, Langley RG. Efficacy and Safety of Continuous Risankizumab Therapy vs Treatment Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: A Phase 3 Randomized Clinical Trial. Jama Dermatology. PMID 32267471 DOI: 10.1001/Jamadermatol.2020.0723  0.256
2012 Williams DA. Review of internet-based interventions for pain finds some evidence to support the effectiveness of cognitive and behavioural interventions, but further quality study is needed to assess the effect of peer support and social networking programmes. Evidence-Based Nursing. 15: 41-2. PMID 22187498 DOI: 10.1136/Ebnurs.2011.100293  0.256
1998 Naliboff B, Williams DA, Salters K, Reyes R, Mayer EA. Symptom beliefs and their relationship to functional status in IBS and chronic pain Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83302-7  0.255
2011 Gottlieb AB, Leonardi C, Kerdel F, Mehlis S, Olds M, Williams DA. Efficacy and safety of briakinumab vs. etanercept and placebo in patients with moderate to severe chronic plaque psoriasis. The British Journal of Dermatology. 165: 652-60. PMID 21574983 DOI: 10.1111/J.1365-2133.2011.10418.X  0.255
2016 Schrepf A, Harper DE, Williams DA, Hassett AL, Harte SE. Somatic Awareness and Tender Points in a Community Sample. The Journal of Pain : Official Journal of the American Pain Society. 17: 1281-1290. PMID 27589911 DOI: 10.1016/J.Jpain.2016.08.009  0.255
2008 Geisser ME, Strader Donnell C, Petzke F, Gracely RH, Clauw DJ, Williams DA. Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanism. Psychosomatics. 49: 235-42. PMID 18448779 DOI: 10.1176/Appi.Psy.49.3.235  0.255
2003 Donta ST, Clauw DJ, Engel CC, Guarino P, Peduzzi P, Williams DA, Skinner JS, Barkhuizen A, Taylor T, Kazis LE, Sogg S, Hunt SC, Dougherty CM, Richardson RD, Kunkel C, et al. Cognitive behavioral therapy and aerobic exercise for Gulf War veterans' illnesses: a randomized controlled trial. Jama. 289: 1396-404. PMID 12636462 DOI: 10.1001/Jama.289.11.1396  0.255
2017 Lai HH, Jemielita T, Bradley CS, Naliboff B, Gereau R, Williams DA, Kreder K, Clemens JQ, Rodriguez LV, Krieger JN, Farrar JT, Robinson N, Landis JR. MP29-12 USE OF A BODY PAIN MAP TO CHARACTERIZE UROLOGIC CHRONIC PELVIC PAIN SYNDROME – A MAPP RESEARCH NETWORK STUDY Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.924  0.255
2020 Armstrong AW, Puig L, Joshi A, Skup M, Williams D, Li J, Betts KA, Augustin M. Comparison of Biologics and Oral Treatments for Plaque Psoriasis: A Meta-analysis. Jama Dermatology. PMID 32022825 DOI: 10.1001/Jamadermatol.2019.4029  0.255
2017 Schrepf A, Harte SE, Miller N, Fowler C, Nay C, Williams DA, Clauw DJ, Rothberg A. Improvement in the Spatial Distribution of Pain, Somatic Symptoms, and Depression Following a Weight-Loss Intervention. The Journal of Pain : Official Journal of the American Pain Society. PMID 28847734 DOI: 10.1016/J.Jpain.2017.08.004  0.255
2013 Smallwood RF, Laird AR, Ramage AE, Parkinson AL, Lewis J, Clauw DJ, Williams DA, Schmidt-Wilcke T, Farrell MJ, Eickhoff SB, Robin DA. Structural brain anomalies and chronic pain: a quantitative meta-analysis of gray matter volume. The Journal of Pain : Official Journal of the American Pain Society. 14: 663-75. PMID 23685185 DOI: 10.1016/J.Jpain.2013.03.001  0.254
2017 Burgess H, Park M, Ong J, Shakoor N, Williams D, Burns J. 1010 MORNING BRIGHT LIGHT TREATMENT IMPROVES FUNCTION AND REDUCES PAIN SENSITIVITY IN FIBROMYALGIA Sleep. 40: A376-A376. DOI: 10.1093/Sleepj/Zsx050.1009  0.254
2011 Williams DA, Clauw DJ, Glass JM. Perceived cognitive dysfunction in fibromyalgia syndrome Journal of Musculoskeletal Pain. 19: 66-75. DOI: 10.3109/10582452.2011.558989  0.254
2012 Gordon KB, Langley RG, Gottlieb AB, Papp KA, Krueger GG, Strober BE, Williams DA, Gu Y, Valdes JM. A phase III, randomized, controlled trial of the fully human IL-12/23 mAb briakinumab in moderate-to-severe psoriasis. The Journal of Investigative Dermatology. 132: 304-14. PMID 22011907 DOI: 10.1038/Jid.2011.304  0.254
1996 Du X, Everett ET, Wang G, Lee WH, Yang Z, Williams DA. Murine interleukin-11 (IL-11) is expressed at high levels in the hippocampus and expression is developmentally regulated in the testis. Journal of Cellular Physiology. 168: 362-372. PMID 8707872 DOI: 10.1002/(Sici)1097-4652(199608)168:2<362::Aid-Jcp15>3.0.Co;2-5  0.254
1999 Hayes A, Williams DA. Examining potential drug therapies for muscular dystrophy utilising the dy/dy mouse: I. Clenbuterol. Journal of the Neurological Sciences. 157: 122-8. PMID 9619633 DOI: 10.1016/S0022-510X(98)00084-7  0.254
1991 Gil KM, Williams DA, Thompson RJ, Kinney TR. Sickle cell disease in children and adolescents: the relation of child and parent pain coping strategies to adjustment. Journal of Pediatric Psychology. 16: 643-63. PMID 1744811 DOI: 10.1093/Jpepsy/16.5.643  0.254
2020 Brendel C, Williams DA. Current and future gene therapies for hemoglobinopathies. Current Opinion in Hematology. PMID 32205585 DOI: 10.1097/Moh.0000000000000581  0.253
2012 Murphy KT, Ham DJ, Church JE, Naim T, Trieu J, Williams DA, Lynch GS. Parvalbumin gene transfer impairs skeletal muscle contractility in old mice. Human Gene Therapy. 23: 824-36. PMID 22455364 DOI: 10.1089/Hum.2011.210  0.253
2017 Burgess HJ, Park M, Ong JC, Shakoor N, Williams DA, Burns J. Morning Versus Evening Bright Light Treatment at Home to Improve Function and Pain Sensitivity for Women with Fibromyalgia: A Pilot Study. Pain Medicine (Malden, Mass.). 18: 116-123. PMID 27473633 DOI: 10.1093/Pm/Pnw160  0.252
1993 Tota-Faucette ME, Gil KM, Williams DA, Keefe FJ, Goli V. Predictors of response to pain management treatment. The role of family environment and changes in cognitive processes. The Clinical Journal of Pain. 9: 115-23. PMID 8358134 DOI: 10.1097/00002508-199306000-00006  0.252
2006 Williams DA, Gracely RH. Biology and therapy of fibromyalgia. Functional magnetic resonance imaging findings in fibromyalgia. Arthritis Research & Therapy. 8: 224. PMID 17254318 DOI: 10.1186/Ar2094  0.252
2011 Murphy SL, Lyden AK, Clary M, Geisser ME, Yung RL, Clauw DJ, Williams DA. Activity pacing for osteoarthritis symptom management: study design and methodology of a randomized trial testing a tailored clinical approach using accelerometers for veterans and non-veterans. Bmc Musculoskeletal Disorders. 12: 177. PMID 21810253 DOI: 10.1186/1471-2474-12-177  0.252
1991 Davis PW, Williams DA, Shamberger RC. Immune thrombocytopenia: Surgical therapy and predictors of response Journal of Pediatric Surgery. 26: 407-413. PMID 2056400 DOI: 10.1016/0022-3468(91)90987-5  0.252
2019 Schrepf A, Phan V, Clemens JQ, Maixner W, Hanauer D, Williams DA. ICD-10 codes for the study of chronic overlapping pain conditions in administrative databases. The Journal of Pain : Official Journal of the American Pain Society. PMID 31154033 DOI: 10.1016/J.Jpain.2019.05.007  0.252
2009 Ali AM, Kirby M, Jansen M, Lach FP, Schulte J, Singh TR, Batish SD, Auerbach AD, Williams DA, Meetei AR. Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group. Human Mutation. 30: E761-70. PMID 19405097 DOI: 10.1002/Humu.21032  0.252
2012 Murphy SL, Kratz AL, Williams DA, Geisser ME. The Association between Symptoms, Pain Coping Strategies, and Physical Activity Among People with Symptomatic Knee and Hip Osteoarthritis. Frontiers in Psychology. 3: 326. PMID 22969747 DOI: 10.3389/Fpsyg.2012.00326  0.251
2006 Schambach A, Galla M, Modlich U, Will E, Chandra S, Reeves L, Colbert M, Williams DA, von Kalle C, Baum C. Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research. Experimental Hematology. 34: 588-92. PMID 16647564 DOI: 10.1016/J.Exphem.2006.02.005  0.251
1990 Gehring CA, Williams DA, Cody SH, Parish RW. Phototropism and geotropism in maize coleoptiles are spatially correlated with increases in cytosolic free calcium. Nature. 345: 528-530. PMID 11540625 DOI: 10.1038/345528A0  0.251
2013 Ciuculescu F, Gonchi PN, De Vita S, McGuinness M, Mathieu R, Harris C, Williams D. Deletion of murine Rac gtpases in the perivascular niche disrupts trabecular bone formation, medullary blood vessels and hematopoiesis Experimental Hematology. 41: S14. DOI: 10.1016/J.Exphem.2013.05.052  0.251
2004 Williams D, Baum C. Gene therapy needs both trials and new strategies Nature. 429: 129-129. PMID 15141184 DOI: 10.1038/429129C  0.25
2009 Amsterdam JD, Williams D, Michelson D, Adler LA, Dunner DL, Nierenberg AA, Reimherr FW, Schatzberg AF. Tachyphylaxis after repeated antidepressant drug exposure in patients with recurrent major depressive disorder. Neuropsychobiology. 59: 227-33. PMID 19571597 DOI: 10.1159/000226611  0.25
1991 Keefe FJ, Fillingim RB, Williams DA. Behavioral Assessment of Pain: Nonverbal Measures in Animals and Humans Ilar Journal. 33: 3-13. DOI: 10.1093/Ilar.33.1-2.3  0.25
1995 Ginsberg B, Gil KM, Muir M, Sullivan F, Williams DA, Glass PSA. The influence of lockout intervals and drug selection on patient-controlled analgesia following gynecological surgery Pain. 62: 95-100. PMID 7478713 DOI: 10.1016/0304-3959(94)00255-D  0.25
2014 Schmidt-Wilcke T, Kairys A, Ichesco E, Fernandez-Sanchez ML, Barjola P, Heitzeg M, Harris RE, Clauw DJ, Glass J, Williams DA. Changes in clinical pain in fibromyalgia patients correlate with changes in brain activation in the cingulate cortex in a response inhibition task. Pain Medicine (Malden, Mass.). 15: 1346-58. PMID 24995850 DOI: 10.1111/Pme.12460  0.25
2013 Williams DA. The importance of psychological assessment in chronic pain. Current Opinion in Urology. 23: 554-9. PMID 24080806 DOI: 10.1097/Mou.0B013E3283652Af1  0.25
2014 Lier A, Walter D, Geiselhart A, Huntscha S, Brocks D, Bayindir I, Kaschutnig P, Müdder K, Holland-Letz T, Schmezer P, Sobotta M, Dick T, Lane S, Essers M, Williams D, et al. Stress-induced exit from dormancy alters redox signaling in HSCs, resulting in de novo DNA damage and bone marrow failure in the absence of a functional fanconi anemia signaling pathway Experimental Hematology. 42: S45. DOI: 10.1016/J.Exphem.2014.07.168  0.25
2012 Keller RB, Gagne KE, Usmani GN, Asdourian GK, Williams DA, Hofmann I, Agarwal S. CTC1 Mutations in a patient with dyskeratosis congenita. Pediatric Blood & Cancer. 59: 311-4. PMID 22532422 DOI: 10.1002/Pbc.24193  0.25
2018 Horiguchi H, Ciuculescu MF, Troeger A, Xu H, Brendel C, Williams DA. Deletion of Murine Rhoh induces More Aggressive Diffuse Large B Cell Lymphoma (DLBCL) Via Interaction with Kaiso and Regulation of BCL-6 Expression Blood. 132: 1574-1574. DOI: 10.1182/Blood-2018-99-115238  0.25
2007 Williams DA. ASGT advises NIH on funding of gene therapy trials Molecular Therapy. 15: 1-2. PMID 17164764 DOI: 10.1038/Sj.Mt.6300051  0.249
2006 Williams DA. NIH Funding of Gene Therapy Trials Molecular Therapy. 14: 607. PMID 16979942 DOI: 10.1016/J.Ymthe.2006.09.004  0.249
2019 Boehnke KF, Scott JR, Litinas E, Sisley S, Clauw DJ, Goesling J, Williams DA. Cannabis use preferences and decision making among a cross-sectional cohort of medical cannabis patients with chronic pain. The Journal of Pain : Official Journal of the American Pain Society. PMID 31132510 DOI: 10.1016/J.Jpain.2019.05.009  0.248
1998 Compas BE, Haaga DA, Keefe FJ, Leitenberg H, Williams DA. Sampling of empirically supported psychological treatments from health psychology: smoking, chronic pain, cancer, and bulimia nervosa. Journal of Consulting and Clinical Psychology. 66: 89-112. PMID 9489263 DOI: 10.1037/0022-006X.66.1.89  0.248
2023 Labrosse R, Chu J, Armant M, Everett JK, Pellin D, Kareddy N, Frelinger AL, Henderson LA, O'Connell AE, Biswas A, Coenen-van der Spek J, Miggelbrink AM, Fiorini C, Adhikari H, Berry CC, ... ... Williams DA, et al. Outcomes of Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome. Blood. PMID 37478401 DOI: 10.1182/blood.2022019117  0.247
2019 Reich K, Gooderham M, Thaçi D, Crowley JJ, Ryan C, Krueger JG, Tsai TF, Flack M, Gu Y, Williams DA, Thompson EHZ, Paul C. Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial. Lancet (London, England). PMID 31280967 DOI: 10.1016/S0140-6736(19)30952-3  0.247
2015 Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA. Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study. The Journal of Urology. 193: 1254-62. PMID 25444992 DOI: 10.1016/J.Juro.2014.10.086  0.247
1998 Hayes A, Williams DA. Contractile function and low-intensity exercise effects of old dystrophic ( mdx) mice. American Journal of Physiology. Cell Physiology. 274: C1138-C1144. PMID 29585812 DOI: 10.1152/Ajpcell.1998.274.4.C1138  0.247
2010 Barrett GL, Reid CA, Tsafoulis C, Zhu W, Williams DA, Paolini AG, Trieu J, Murphy M. Enhanced spatial memory and hippocampal long-term potentiation in p75 neurotrophin receptor knockout mice. Hippocampus. 20: 145-52. PMID 19360854 DOI: 10.1002/Hipo.20598  0.247
2013 Burmester G, Emery P, Signorovitch J, Williams D, Valdes J, Bao Y, Mulani P. FRI0145 The effect of adalimumab on risk of major adverse cardiovascular events in rheumatoid arthritis: A meta-analysis of randomized trials: Annals of the Rheumatic Diseases. 71: 359.3-360. DOI: 10.1136/Annrheumdis-2012-Eular.2602  0.247
2016 Kimball AB, Okun MM, Williams DA, Gottlieb AB, Papp KA, Zouboulis CC, Armstrong AW, Kerdel F, Gold MH, Forman SB, Korman NJ, Giamarellos-Bourboulis EJ, Crowley JJ, Lynde C, Reguiai Z, et al. Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa. The New England Journal of Medicine. 375: 422-34. PMID 27518661 DOI: 10.1056/Nejmoa1504370  0.247
1999 Grosfeld JL, Du X, Williams DA. Interleukin-11: its biology and prospects for clinical use. Jpen. Journal of Parenteral and Enteral Nutrition. 23: S67-9. PMID 10483899 DOI: 10.1177/014860719902300517  0.247
2000 Bennell K, Page C, Khan K, Warmington S, Plant D, Thomas D, Palamara J, Williams D, Wark JD. Effects of resistance training on bone parameters in young and mature rats. Clinical and Experimental Pharmacology and Physiology. 27: 88-94. PMID 10696534 DOI: 10.1046/J.1440-1681.2000.03211.X  0.247
2001 Williams DA. Inflammatory cytokines and mucosal injury Journal of the National Cancer Institute. Monographs. 26-30. PMID 11694562 DOI: 10.1093/Oxfordjournals.Jncimonographs.A003435  0.247
2012 Konstantinidis DG, Pushkaran S, Johnson JF, Cancelas JA, Manganaris S, Harris CE, Williams DA, Zheng Y, Kalfa TA. Signaling and cytoskeletal requirements in erythroblast enucleation. Blood. 119: 6118-27. PMID 22461493 DOI: 10.1182/Blood-2011-09-379263  0.247
2009 Mease P, Arnold LM, Choy EH, Clauw DJ, Crofford LJ, Glass JM, Martin SA, Morea J, Simon L, Strand CV, Williams DA. Fibromyalgia syndrome module at OMERACT 9: domain construct. The Journal of Rheumatology. 36: 2318-29. PMID 19820221 DOI: 10.3899/Jrheum.090367  0.247
2014 Lee YC, Frits ML, Iannaccone CK, Weinblatt ME, Shadick NA, Williams DA, Cui J. Subgrouping of patients with rheumatoid arthritis based on pain, fatigue, inflammation, and psychosocial factors. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2006-14. PMID 24782222 DOI: 10.1002/Art.38682  0.247
2016 Horneff G, Seyger MMB, Arikan D, Kalabic J, Anderson JK, Lazar A, Williams DA, Wang C, Tarzynski-Potempa R, Hyams JS. THU0214 Safety of Adalimumab in Pediatric Patients with Polyarticular Juvenile Idiopathic Arthritis, Enthesitis-Related Arthritis, Psoriasis, and Crohn's Disease Annals of the Rheumatic Diseases. 75: 265-265. DOI: 10.1136/Annrheumdis-2016-Eular.4386  0.247
1997 Du X, Liu Q, Yang Z, Orazi A, Rescorla FJ, Grosfeld JL, Williams DA. Protective effects of interleukin-11 in a murine model of ischemic bowel necrosis. The American Journal of Physiology. 272: G545-52. PMID 9124575 DOI: 10.1152/Ajpgi.1997.272.3.G545  0.246
1986 Williams DA, Orkin SH. Somatic gene therapy. Current status and future prospects Journal of Clinical Investigation. 77: 1053-1056. PMID 3514670 DOI: 10.1172/Jci112403  0.246
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