| Year |
Citation |
Score |
| 2024 |
Schiroli G, Kartha V, Duarte FM, Kristiansen TA, Mayerhofer C, Shrestha R, Earl A, Hu Y, Tay T, Rhee C, Buenrostro JD, Scadden DT. Cell of origin epigenetic priming determines susceptibility to Tet2 mutation. Nature Communications. 15: 4325. PMID 38773071 DOI: 10.1038/s41467-024-48508-6 |
0.754 |
|
| 2024 |
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, ... ... Scadden DT, et al. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood. PMID 38447038 DOI: 10.1182/blood.2023023549 |
0.325 |
|
| 2024 |
Kristiansen T, Mayerhofer C, Gustafsson K, Scadden DT. Stromal Cell Isolation from Hematopoietic Organs. Journal of Visualized Experiments : Jove. PMID 38345255 DOI: 10.3791/66231 |
0.373 |
|
| 2024 |
Mei S, Alchahin AM, Tsea I, Kfoury Y, Hirz T, Jeffries NE, Zhao T, Xu Y, Zhang H, Sarkar H, Wu S, Subtelny AO, Johnsen JI, Zhang Y, Salari K, ... ... Scadden DT, et al. Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions. Genome Medicine. 16: 1. PMID 38281962 DOI: 10.1186/s13073-023-01272-6 |
0.321 |
|
| 2023 |
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee IH, Mentkowski K, Grune J, Schloss MJ, Honold L, Iwamoto Y, Zheng Y, Bredella MA, Buckless C, Ghoshhajra B, ... ... Scadden D, et al. Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction. Nature Cardiovascular Research. 2: 1277-1290. PMID 38344689 DOI: 10.1038/s44161-023-00388-7 |
0.331 |
|
| 2023 |
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy S, Boitano A, Nahrendorf M, Scadden DT. Clearing and replacing tissue-resident myeloid cells with an anti-CD45-antibody-drug conjugate. Blood Advances. PMID 37748049 DOI: 10.1182/bloodadvances.2023010561 |
0.786 |
|
| 2023 |
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy SL, Boitano AE, Nahrendorf M, Scadden DT. CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer. Biorxiv : the Preprint Server For Biology. PMID 37732224 DOI: 10.1101/2023.09.05.556397 |
0.789 |
|
| 2023 |
Miller PG, Sperling AS, Mayerhofer C, McConkey M, Ellegast JM, Da Silva C, Cohen DN, Wang C, Sharda A, Yan N, Saha S, Schluter C, Schechter IA, Słabicki M, Sandoval B, ... ... Scadden DT, et al. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. PMID 37595362 DOI: 10.1182/blood.2023020331 |
0.3 |
|
| 2023 |
Kfoury YS, Ji F, Jain E, Mazzola MC, Schiroli G, Papazian A, Mercier FE, Sykes DB, Kiem A, Randolph MA, Abdel-Wahab OI, Calvi LM, Sadreyev R, Scadden DT. The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression. Blood Advances. PMID 37450380 DOI: 10.1182/bloodadvances.2022008268 |
0.451 |
|
| 2023 |
Rhee C, Scadden EW, Wong LP, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee BK, Kim J, Nahrendorf M, Mansour M, Sykes DB, Sadreyev R, ... Scadden DT, et al. Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors. Blood. PMID 37267513 DOI: 10.1182/blood.2023020257 |
0.801 |
|
| 2023 |
Kawano Y, Kawano H, Ghoneim D, Fountaine TJ, Byun DK, LaMere MW, Mendler JH, Ho T, Salama NA, Myers JR, Hussein SE, Frisch BJ, Ashton JM, Azadniv M, Liesveld JL, ... ... Scadden DT, et al. Myelodysplastic syndromes disable human CD271 VCAM1 CD146 niches supporting normal hematopoietic stem/progenitor cells. Biorxiv : the Preprint Server For Biology. PMID 37066307 DOI: 10.1101/2023.04.09.536176 |
0.394 |
|
| 2022 |
Gustafsson K, Scadden DT. Isolation of Thymus Stromal Cells from Human and Murine Tissue. Methods in Molecular Biology (Clifton, N.J.). 2567: 191-201. PMID 36255703 DOI: 10.1007/978-1-0716-2679-5_13 |
0.352 |
|
| 2022 |
Torres LS, Asada N, Weiss MJ, Trumpp A, Suda T, Scadden DT, Ito K. Recent advances in "sickle and niche" research - Tribute to Dr. Paul S Frenette. Stem Cell Reports. 17: 1509-1535. PMID 35830837 DOI: 10.1016/j.stemcr.2022.06.004 |
0.352 |
|
| 2022 |
Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, ... ... Scadden DT, et al. B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nature Immunology. PMID 35352063 DOI: 10.1038/s41590-022-01165-7 |
0.37 |
|
| 2021 |
Fast EM, Sporrij A, Manning M, Rocha EL, Yang S, Zhou Y, Guo J, Baryawno N, Barkas N, Scadden D, Camargo F, Zon LI. External signals regulate continuous transcriptional states in hematopoietic stem cells. Elife. 10. PMID 34939923 DOI: 10.7554/eLife.66512 |
0.349 |
|
| 2021 |
Blanco MA, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, Jambhekar A, Cheloufi S, Meissner A, Hochedlinger K, Scadden DT, et al. Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports. 37: 109967. PMID 34758323 DOI: 10.1016/j.celrep.2021.109967 |
0.337 |
|
| 2021 |
van Gastel N, Spinelli JB, Haigis MC, Scadden DT. Analysis of Leukemia Cell Metabolism through Stable Isotope Tracing in Mice. Bio-Protocol. 11: e4171. PMID 34722818 DOI: 10.21769/BioProtoc.4171 |
0.317 |
|
| 2021 |
Shah NJ, Mao AS, Shih TY, Kerr MD, Sharda A, Raimondo TM, Weaver JC, Vrbanac VD, Deruaz M, Tager AM, Mooney DJ, Scadden DT. Author Correction: An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation. Nature Biotechnology. PMID 34663922 DOI: 10.1038/s41587-021-01081-5 |
0.401 |
|
| 2021 |
van Gastel N, Scadden DT. Young haematopoietic stem cells are picky eaters. Cell Research. PMID 33633351 DOI: 10.1038/s41422-021-00488-8 |
0.378 |
|
| 2021 |
Oki T, Mercier F, Kato H, Jung Y, McDonald TO, Spencer JA, Mazzola MC, van Gastel N, Lin CP, Michor F, Kitamura T, Scadden DT. Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML. Nature Communications. 12: 245. PMID 33431855 DOI: 10.1038/s41467-020-20491-8 |
0.313 |
|
| 2020 |
Shen YJ, Mishima Y, Shi J, Sklavenitis-Pistofidis R, Redd RA, Moschetta M, Manier S, Roccaro AM, Sacco A, Tai YT, Mercier FE, Kawano Y, Su NK, Berrios B, Doench J, ... ... Scadden DT, et al. Progression signature underlies clonal evolution and dissemination of multiple myeloma. Blood. PMID 33150374 DOI: 10.1016/J.Clml.2019.09.028 |
0.377 |
|
| 2020 |
Fang S, Chen S, Nurmi H, Leppänen VM, Jeltsch M, Scadden DT, Silberstein L, Mikkola H, Alitalo K. VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche. Blood. PMID 32842144 DOI: 10.1182/Blood.2020005699 |
0.452 |
|
| 2020 |
Kokkaliaris KD, Scadden DT. Cell interactions in the bone marrow microenvironment affecting myeloid malignancies. Blood Advances. 4: 3795-3803. PMID 32780848 DOI: 10.1182/Bloodadvances.2020002127 |
0.496 |
|
| 2020 |
Kokkaliaris K, Kunz L, Cabezas-Wallscheid N, Christodoulou C, Renders S, Camargo F, Trumpp A, Scadden DT, Schroeder T. Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations. Blood. PMID 32766876 DOI: 10.1182/Blood.2020006574 |
0.48 |
|
| 2020 |
van Gastel N, Spinelli JB, Sharda A, Schajnovitz A, Baryawno N, Rhee C, Oki T, Grace E, Soled HJ, Milosevic J, Sykes DB, Hsu PP, Vander Heiden MG, Vidoudez C, Trauger SA, ... ... Scadden DT, et al. Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance. Cell Metabolism. PMID 32763164 DOI: 10.1016/J.Cmet.2020.07.009 |
0.79 |
|
| 2020 |
Yusuf R, Saez B, Sharda A, van Gastel N, Yu V, Baryawno N, Scadden EW, Acharya SS, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, ... ... Scadden DT, et al. Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers. Blood. PMID 32458004 DOI: 10.1182/Blood.2019001808 |
0.433 |
|
| 2020 |
Castiello MC, Bosticardo M, Sacchetti N, Calzoni E, Fontana E, Yamazaki Y, Draghici E, Corsino C, Bortolomai I, Sereni L, Yu HH, Uva P, Palchaudhuri R, Scadden DT, Villa A, et al. Efficacy and safety of anti-CD45-Saporin as conditioning agent for RAG deficiency. The Journal of Allergy and Clinical Immunology. PMID 32387109 DOI: 10.1016/J.Jaci.2020.04.033 |
0.39 |
|
| 2020 |
Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, Kiem HP. Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Molecular Therapy. Methods & Clinical Development. 17: 455-464. PMID 32226796 DOI: 10.1016/J.Omtm.2020.02.001 |
0.476 |
|
| 2020 |
van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls VW, Baryawno N, Przybylski D, Depypere M, Stiers PJ, Lambrechts D, Van Looveren R, Torrekens S, Sharda A, Agostinis P, ... ... Scadden DT, et al. Lipid availability determines fate of skeletal progenitor cells via SOX9. Nature. PMID 32103177 DOI: 10.1038/S41586-020-2050-1 |
0.404 |
|
| 2020 |
Shah NJ, Najibi AJ, Shih TY, Mao AS, Sharda A, Scadden DT, Mooney DJ. A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia. Nature Biomedical Engineering. PMID 31937942 DOI: 10.1038/S41551-019-0503-3 |
0.387 |
|
| 2020 |
Dipersio J, Devine S, Hoggatt J, Scadden D, Howell H, Schmelmer V, Neale J, Boitano T, Cooke M, Morrow D, Raffel G, Savage W, Goncalves K, Falahee P, Davis J. Fri0235 Phase 1 Clinical Study Of Mgta-145 In Combination With Plerixafor Shows Rapid Single-Day Mobilisation And Collection Of Cd34+ Haematopoietic Stem Cells Without G-Csf Annals of the Rheumatic Diseases. 79: 701-702. DOI: 10.1136/Annrheumdis-2020-Eular.3750 |
0.414 |
|
| 2020 |
DiPersio JF, Devine SM, Hoggatt J, Scadden D, Howell H, Schmelmer V, Neale J, Boitano AE, Cooke MP, Goncalves KA, Raffel GD, Savage W, Falahee PC, Morrow DM, Davis JC. Phase 1 Clinical Study of Mgta-145 in Combination with Plerixafor Shows Rapid Single-Day Mobilization and Collection of CD34+ HSCs without G-CSF Biology of Blood and Marrow Transplantation. 26: S55. DOI: 10.1016/J.Bbmt.2019.12.129 |
0.391 |
|
| 2019 |
Ortinau LC, Wang H, Lei K, Deveza L, Jeong Y, Hara Y, Grafe I, Rosenfeld SB, Lee D, Lee B, Scadden DT, Park D. Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells. Cell Stem Cell. 25: 784-796.e5. PMID 31809737 DOI: 10.1016/J.Stem.2019.11.003 |
0.455 |
|
| 2019 |
Scadden DT. Metcalf Lecture Award Manuscript: Applying niche biology to engineer T-cell regenerative therapies. Experimental Hematology. PMID 31765673 DOI: 10.1016/J.Exphem.2019.11.004 |
0.506 |
|
| 2019 |
Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, ... ... Scadden DT, et al. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nature Medicine. PMID 31700184 DOI: 10.1038/S41591-019-0633-X |
0.415 |
|
| 2019 |
Mao AS, Özkale B, Shah NJ, Vining KH, Descombes T, Zhang L, Tringides CM, Wong SW, Shin JW, Scadden DT, Weitz DA, Mooney DJ. Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31311862 DOI: 10.1073/Pnas.1819415116 |
0.506 |
|
| 2019 |
Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. PMID 31279774 DOI: 10.1016/J.Stem.2019.06.003 |
0.802 |
|
| 2019 |
Baryawno N, Przybylski D, Kowalczyk MS, Kfoury Y, Severe N, Gustafsson K, Kokkaliaris KD, Mercier F, Tabaka M, Hofree M, Dionne D, Papazian A, Lee D, Ashenberg O, Subramanian A, ... ... Scadden DT, et al. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. Cell. PMID 31130381 DOI: 10.1016/J.Cell.2019.04.040 |
0.516 |
|
| 2019 |
Gustafsson K, Scadden DT. Growing old in the age of heterogeneity: the perils of shifting clonality. Current Opinion in Hematology. PMID 31045646 DOI: 10.1097/Moh.0000000000000513 |
0.406 |
|
| 2019 |
Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS. Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell. PMID 31006621 DOI: 10.1016/J.Stem.2019.03.020 |
0.671 |
|
| 2019 |
Christian S, Merz C, Evans L, Gradl S, Seidel H, Friberg A, Eheim A, Lejeune P, Brzezinka K, Zimmermann K, Ferrara S, Meyer H, Lesche R, Stoeckigt D, Bauser M, ... ... Scadden DT, et al. The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia. PMID 30940908 DOI: 10.1038/S41375-019-0461-5 |
0.346 |
|
| 2019 |
Ni F, Yu WM, Wang X, Fay ME, Young KM, Qiu Y, Lam WA, Sulchek TA, Cheng T, Scadden DT, Qu CK. Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell Stem Cell. PMID 30880025 DOI: 10.1016/J.Stem.2019.02.009 |
0.527 |
|
| 2019 |
Shah NJ, Mao AS, Shih TY, Kerr MD, Sharda A, Raimondo TM, Weaver JC, Vrbanac VD, Deruaz M, Tager AM, Mooney DJ, Scadden DT. An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation. Nature Biotechnology. PMID 30742125 DOI: 10.1038/S41587-019-0017-2 |
0.482 |
|
| 2019 |
Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Hoggatt J, Saez B, Pang WW, Mansour MK, Tate TA, Chan YY, Walck E, Wernig G, Shizuru JA, Winau F, Scadden DT, et al. Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. Nature Communications. 10: 617. PMID 30728354 DOI: 10.1038/S41467-018-08201-X |
0.801 |
|
| 2019 |
Fountaine TJ, LaMere MW, Byun DK, Myers JR, Ashton JM, Liesveld JL, Kfoury Y, Scadden DT, Becker MW, Calvi LM. A Specific Mesenchymal Stem and Progenitor Cell (MSPC) Subpopulation with a Multi-Potent Gene Signature Is Transcriptionally Altered in the Setting of Myelodysplastic Syndrome (MDS) in Primary Human Bone Marrow Aspirates Blood. 134: 1708-1708. DOI: 10.1182/Blood-2019-130227 |
0.423 |
|
| 2019 |
Gustafsson K, Barkas N, Baryawno N, Scadden EW, Severe N, Spencer JA, Gessessew H, Kooshesh K, Guo J, Lin C, Kharchenko P, Scadden DT. Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations Blood. 134: 586-586. DOI: 10.1182/Blood-2019-126708 |
0.524 |
|
| 2019 |
Kfoury Y, Ji F, Mazzola M, Sykes DB, Anthony A, Akiyama Y, Scherer A, Mercier F, Severe N, Saez B, Seidl J, Papazian A, Brouse T, Mansour MK, Ivanov P, ... ... Scadden DT, et al. Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to Stress Blood. 134: 1207-1207. DOI: 10.1182/Blood-2019-124794 |
0.485 |
|
| 2019 |
van Gastel N, Spinelli JB, Sharda A, Schajnovitz A, Baryawno N, Rhee CS, Oki T, Grace E, Soled HJ, Vidoudez C, Trauger SA, Haigis MC, Scadden DT. The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance Blood. 134: 3725-3725. DOI: 10.1182/Blood-2019-124789 |
0.798 |
|
| 2019 |
Rhee CS, Scadden EW, Phillip CL, Lee B, Mistry M, Hoyer FF, Kato H, Mantica G, Kim J, Nahrendorf M, Mansour MK, Sykes DB, Scadden DT. Functionally Distinct Subsets of Monocytes in Mouse and Human Blood Blood. 134: 438-438. DOI: 10.1182/Blood-2019-124054 |
0.83 |
|
| 2019 |
Man C, Scadden DT, Mercier F, Liu N, Dong W, Stephanopoulos G, Jiang L, Jung Y, Lin C, Leung AY. Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting Blood. 134: 3765-3765. DOI: 10.1182/Blood-2019-123604 |
0.422 |
|
| 2019 |
Eheim A, Christian S, Meyer H, Stoeckigt D, Merz C, Zimmermann K, Bauser M, Haegebarth A, Ferrara S, Sykes DB, Scadden DT, Gradl S, Janzer A. Abstract 3597: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of diffuse large B-cell lymphoma (DLBCL) Cancer Research. 79: 3597-3597. DOI: 10.1158/1538-7445.Am2019-3597 |
0.402 |
|
| 2019 |
Gradl SN, Mueller T, Ferrara S, Sheikh SE, Janzer A, Zhou H, Friberg A, Guenther J, Schaefer M, Stellfeld T, Eis K, Kroeber M, Nguyen D, Merz C, Niehues M, ... ... Scadden DT, et al. Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies Cancer Research. 79: 2-2. DOI: 10.1158/1538-7445.Am2019-2 |
0.312 |
|
| 2019 |
Scadden D. 1001 - PRIMITIVE SENSING AND COMMUNICATION MECHANISMS REGULATING BONE MARROW Experimental Hematology. 76: S23. DOI: 10.1016/J.Exphem.2019.06.239 |
0.485 |
|
| 2018 |
Galvin A, Weglarz M, Folz-Donahue K, Handley M, Baum M, Mazzola M, Litwa H, Scadden DT, Silberstein L. Cell Cycle Analysis of Hematopoietic Stem and Progenitor Cells by Multicolor Flow Cytometry. Current Protocols in Cytometry. e50. PMID 30335223 DOI: 10.1002/Cpcy.50 |
0.484 |
|
| 2018 |
Almeida FF, Tognarelli S, Marçais A, Kueh AJ, Friede ME, Liao Y, Willis SN, Luong K, Faure F, Mercier FE, Galluso J, Firth M, Narni-Mancinelli E, Rais B, Scadden DT, et al. A point mutation in the signal peptide impairs the development of innate lymphoid cell subsets. Oncoimmunology. 7: e1475875. PMID 30288342 DOI: 10.1080/2162402X.2018.1475875 |
0.408 |
|
| 2018 |
Ubellacker JM, Baryawno N, Severe N, DeCristo MJ, Sceneay J, Hutchinson JN, Haider MT, Rhee CS, Qin Y, Gregory WM, Garrido-Castro AC, Holen I, Brown JE, Coleman RE, Scadden DT, et al. Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer. Cancer Research. PMID 30065048 DOI: 10.1158/0008-5472.Can-18-0548 |
0.766 |
|
| 2018 |
Petukhov V, Guo J, Baryawno N, Severe N, Scadden DT, Samsonova MG, Kharchenko PV. dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments. Genome Biology. 19: 78. PMID 29921301 DOI: 10.1186/S13059-018-1449-6 |
0.336 |
|
| 2018 |
Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA. The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow. Nature Communications. 9: 2377. PMID 29915352 DOI: 10.1038/S41467-018-04716-5 |
0.369 |
|
| 2018 |
García-Peydró M, Fuentes P, Mosquera M, García-León MJ, Alcain J, Rodríguez A, de Miguel PG, Menéndez P, Weijer K, Spits H, Scadden DT, Cuesta-Mateos C, Muñoz-Calleja C, Sánchez-Madrid F, Toribio ML. The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model. The Journal of Clinical Investigation. PMID 29781813 DOI: 10.1172/Jci92981 |
0.371 |
|
| 2018 |
Xiao P, Dolinska M, Sandhow L, Kondo M, Johansson AS, Bouderlique T, Zhao Y, Li X, Dimitriou M, Rassidakis GZ, Hellström-Lindberg E, Minato N, Walfridsson J, Scadden DT, Sigvardsson M, et al.
deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm. Blood Advances. 2: 534-548. PMID 29514790 DOI: 10.1182/Bloodadvances.2017013599 |
0.521 |
|
| 2018 |
Kfoury Y, Jain E, Myers JR, Ji F, Sykes DB, Mercier F, Papazian A, Le C, Randolph MA, Steensma DP, Abdel-Wahab OI, Calvi LM, Sadreyev RI, Becker MW, Scadden DT. Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells Blood. 132: 938-938. DOI: 10.1182/Blood-2018-99-115242 |
0.453 |
|
| 2018 |
Shen Y, Mishima Y, Shi J, Moschetta M, Manier S, Roccaro AM, Mercier F, Takagi S, Kawano Y, Tsukamoto S, Sahin I, Sacco A, Huynh D, Berrios B, Pistofidis R, ... ... Scadden DT, et al. Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo Blood. 132: 55-55. DOI: 10.1182/Blood-2018-99-113916 |
0.394 |
|
| 2018 |
Hsu PP, Kfoury Y, Aziz N, Elkhoury J, Hallgren B, Scadden DT, Vander Heiden M, Sykes DB. DHODH Inhibitors in the Treatment of Acute Myeloid Leukemia: Defining the Mechanism of Action and the Basis of the Metabolic Therapeutic Window Blood. 132: 2716-2716. DOI: 10.1182/Blood-2018-99-113387 |
0.44 |
|
| 2018 |
Janzer A, Gradl S, Christian S, Zimmermann K, Merz C, Meyer H, Stellfeld T, Guenther J, Stoeckigt D, Seidel H, Lejeune P, Bruening M, Eheim A, Mueller T, Lesche R, ... ... Scadden D, et al. Abstract DDT02-04: BAY 2402234: A novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ddt02-04 |
0.405 |
|
| 2018 |
Mercier F, Shi J, Sykes D, Oki T, Miller E, Vasic R, Zhu A, Severe N, Schajnovitz A, Man C, Kfoury Y, Lee D, Doench J, Hide W, Michor F, ... Scadden D, et al. In Vivo Profiling of Leukemic Stem Cell Fitness Identifies Therapeutically Actionable Determinants of Growth Experimental Hematology. 64: S86. DOI: 10.1016/J.Exphem.2018.06.095 |
0.444 |
|
| 2018 |
Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Winau F, Hoggatt J, Saez B, Mansour MK, Sykes D, Scadden D, Rossi D. Immune Sparing Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins Biology of Blood and Marrow Transplantation. 24: S60-S61. DOI: 10.1016/J.Bbmt.2017.12.633 |
0.739 |
|
| 2017 |
Hoggatt J, Singh P, Tate TA, Chou BK, Datari SR, Fukuda S, Liu L, Kharchenko PV, Schajnovitz A, Baryawno N, Mercier FE, Boyer J, Gardner J, Morrow DM, Scadden DT, et al. Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell. Cell. PMID 29224778 DOI: 10.1016/J.Cell.2017.11.003 |
0.481 |
|
| 2017 |
Dietrich J, Baryawno N, Nayyar N, Valtis YK, Yang B, Ly I, Besnard A, Severe N, Gustafsson KU, Andronesi OC, Batchelor TT, Sahay A, Scadden DT. Bone marrow drives central nervous system regeneration after radiation injury. The Journal of Clinical Investigation. PMID 29202481 DOI: 10.1172/Jci90647 |
0.388 |
|
| 2017 |
Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, ... ... Scadden DT, et al. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science (New York, N.Y.). 358. PMID 29191879 DOI: 10.1126/Science.Aal5081 |
0.382 |
|
| 2017 |
Schiroli G, Ferrari S, Conway A, Jacob A, Capo V, Albano L, Plati T, Castiello MC, Sanvito F, Gennery AR, Bovolenta C, Palchaudhuri R, Scadden DT, Holmes MC, Villa A, et al. Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1. Science Translational Medicine. 9. PMID 29021165 DOI: 10.1126/Scitranslmed.Aan0820 |
0.406 |
|
| 2017 |
Lee PY, Sykes DB, Ameri S, Kalaitzidis D, Charles JF, Nelson-Maney N, Wei K, Cunin P, Morris A, Cardona AE, Root DE, Scadden DT, Nigrovic PA. The metabolic regulator mTORC1 controls terminal myeloid differentiation. Science Immunology. 2. PMID 28763796 DOI: 10.1126/Sciimmunol.Aam6641 |
0.434 |
|
| 2017 |
Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ. ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells. Blood. PMID 28615219 DOI: 10.1182/Blood-2016-09-738591 |
0.714 |
|
| 2017 |
Baryawno N, Severe N, Scadden DT. Hematopoiesis: Reconciling Historic Controversies about the Niche. Cell Stem Cell. 20: 590-592. PMID 28475884 DOI: 10.1016/J.Stem.2017.03.025 |
0.466 |
|
| 2017 |
Kalaitzidis D, Lee D, Efeyan A, Kfoury Y, Nayyar N, Sykes DB, Mercier FE, Papazian A, Baryawno N, Victora GD, Neuberg D, Sabatini DM, Scadden DT. Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells. The Journal of Clinical Investigation. PMID 28319048 DOI: 10.1172/Jci89452 |
0.468 |
|
| 2017 |
Gustafsson K, Scadden DT. Written in bone: young bone makes young blood. The Embo Journal. PMID 28289055 DOI: 10.15252/Embj.201796634 |
0.452 |
|
| 2017 |
Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 168: 944-945. PMID 28235203 DOI: 10.1016/J.Cell.2017.02.010 |
0.426 |
|
| 2017 |
Mercier F, Shi J, Sykes DB, Miller E, Oki T, Man C, Yan X, Kfoury Y, Lee D, Doench JG, Michor F, Scadden DT. A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing Blood. 130: 2493-2493. DOI: 10.1182/Blood.V130.Suppl_1.2493.2493 |
0.433 |
|
| 2017 |
Janzer A, Sykes D, Gradl S, Ferrara S, Christian S, Merz C, Seidel H, Bernthaler A, Lesche R, Wawer M, Scadden DT. Abstract 3086: Inhibitors of the enzyme dihydroorotate dehydrogenase, overcome the differentiation blockade in acute myeloid leukemia Cancer Research. 77: 3086-3086. DOI: 10.1158/1538-7445.Am2017-3086 |
0.388 |
|
| 2017 |
Chattopadhyay S, Huang C, Baryawno N, Severe N, Viswanathan V, Costa C, Scadden D, Schreiber S. Abstract 3026: Targeting GPX4 in tumor-associated stromal cells increases inflammatory-cell infiltration Cancer Research. 77: 3026-3026. DOI: 10.1158/1538-7445.Am2017-3026 |
0.427 |
|
| 2016 |
Papazian AE, Kfoury YS, Scadden DT. Shipping mouse bone marrow: Keep it in the bone. Experimental Hematology. PMID 28043821 DOI: 10.1016/J.Exphem.2016.12.008 |
0.458 |
|
| 2016 |
Lewis TA, Sykes DB, Law JM, Muñoz B, Rustiguel JK, Nonato MC, Scadden DT, Schreiber SL. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. Acs Medicinal Chemistry Letters. 7: 1112-1117. PMID 27994748 DOI: 10.1021/Acsmedchemlett.6B00316 |
0.391 |
|
| 2016 |
Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, ... ... Scadden DT, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nature Medicine. PMID 27941791 DOI: 10.1038/Nm.4242 |
0.405 |
|
| 2016 |
Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 167: 1310-1322.e17. PMID 27863245 DOI: 10.1016/j.cell.2016.10.045 |
0.371 |
|
| 2016 |
Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. PMID 27783593 DOI: 10.1038/Nature20131 |
0.484 |
|
| 2016 |
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, ... ... Scadden DT, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. PMID 27641501 DOI: 10.1016/J.Cell.2016.08.057 |
0.412 |
|
| 2016 |
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, et al. PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2. Molecular Cell. 63: 1006-1020. PMID 27635760 DOI: 10.1016/J.Molcel.2016.08.014 |
0.33 |
|
| 2016 |
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, ... ... Scadden DT, et al. Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators. Cell Stem Cell. PMID 27524439 DOI: 10.1016/J.Stem.2016.07.004 |
0.517 |
|
| 2016 |
Goncalves KA, Silberstein L, Li S, Severe N, Hu MG, Yang H, Scadden DT, Hu GF. Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells. Cell. 166: 894-906. PMID 27518564 DOI: 10.1016/J.Cell.2016.06.042 |
0.517 |
|
| 2016 |
Yu VW, Lymperi S, Oki T, Jones A, Swiatek P, Vasic R, Ferraro F, Scadden DT. Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow. Stem Cell Reports. PMID 27453006 DOI: 10.1016/J.Stemcr.2016.06.009 |
0.528 |
|
| 2016 |
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, ... ... Scadden DT, et al. Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27437586 DOI: 10.1038/Nature19088 |
0.313 |
|
| 2016 |
Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nature Biotechnology. PMID 27272386 DOI: 10.1038/Nbt.3584 |
0.825 |
|
| 2016 |
Hoggatt J, Kfoury Y, Scadden DT. Hematopoietic Stem Cell Niche in Health and Disease. Annual Review of Pathology. 11: 555-81. PMID 27193455 DOI: 10.1146/Annurev-Pathol-012615-044414 |
0.542 |
|
| 2016 |
Mercier FE, Sykes DB, Scadden DT. Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1(STEM) Mouse. Stem Cell Reports. PMID 27185283 DOI: 10.1016/J.Stemcr.2016.04.010 |
0.417 |
|
| 2016 |
Yu VW, Scadden DT. Heterogeneity of the bone marrow niche. Current Opinion in Hematology. PMID 27177311 DOI: 10.1097/Moh.0000000000000265 |
0.432 |
|
| 2016 |
Scadden DT. Blood and Bone. The New England Journal of Medicine. 374: 1891-3. PMID 27168440 DOI: 10.1056/Nejmcibr1601737 |
0.442 |
|
| 2016 |
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, Butler JM, ... ... Scadden DT, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27074509 DOI: 10.1038/Nature17624 |
0.484 |
|
| 2016 |
Lee D, Wang YH, Kalaitzidis D, Ramachandran J, Eda H, Sykes DB, Raje N, Scadden DT. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. The Journal of Clinical Investigation. PMID 26927669 DOI: 10.1172/Jci84620 |
0.33 |
|
| 2016 |
Mishima Y, Shi J, Moschetta M, Shen Y, Manier S, Roccaro AM, Mercier F, Takagi S, Kawano Y, Tsukamoto S, Sahin I, Sacco A, Hatake K, Michor F, Scadden DT, et al. In Vivo Analysis of Clonal Evolution of Multiple Myeloma Blood. 128: 799-799. DOI: 10.1182/Blood.V128.22.799.799 |
0.391 |
|
| 2016 |
Czechowicz A, Palchaudhuri R, Scheck A, Hoggatt J, Saez B, Scadden DT, Rossi DJ. Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins Blood. 128: 493-493. DOI: 10.1182/Blood.V128.22.493.493 |
0.807 |
|
| 2016 |
Severe N, Karabacak M, Baryawno N, Gustafsson K, Kfoury YS, Toner M, Scadden DT. Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis Blood. 128: 430-430. DOI: 10.1182/Blood.V128.22.430.430 |
0.514 |
|
| 2016 |
Silberstein L, Goncalves K, Severe N, Hu G, Scadden DT. Angiogenin Is a Niche-Secreted RNase Which Regulates Hematopoietic Regeneration Blood. 128: 171-171. DOI: 10.1182/Blood.V128.22.171.171 |
0.545 |
|
| 2016 |
Sykes DB, Kfoury YS, Mercier F, Wawer M, Schajnovitz A, Meyer H, Pierce KA, Stoeckigt D, Clish CB, Clemons PA, Janzer A, Scadden DT. Inhibition of the Enzyme Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Blood. 128: 1656-1656. DOI: 10.1182/Blood.V128.22.1656.1656 |
0.48 |
|
| 2016 |
Chattopadhyay S, Huang C, Baryawno N, Severe N, Viswanathan V, Boskovic Z, Mukherjee S, Gentry J, Wittner B, Ramaswamy S, Shamji A, Scadden D, Schreiber S. Abstract B11: Targeting mesenchymal cells in the tumor stroma by GPX4 inhibition Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-B11 |
0.442 |
|
| 2016 |
Silberstein L, Goncalves K, Kharchenko P, Turcotte R, Kfoury Y, Mercier F, Severe N, Baryawno N, Lin C, Scadden D. Proximity-based analysis of the bone marrow niche identifies novel extrinsic regulators of hematopoietic regeneration Experimental Hematology. 44: S100. DOI: 10.1016/J.Exphem.2016.06.218 |
0.402 |
|
| 2016 |
Yu VWC, Scadden DT. Hematopoietic Stem Cell and Its Bone Marrow Niche Current Topics in Developmental Biology. DOI: 10.1016/Bs.Ctdb.2016.01.009 |
0.525 |
|
| 2016 |
Dahéron L, Scadden DT. Generation of Definitive Engraftable Hematopoietic Stem Cells from Human Pluripotent Stem Cells Thomas' Hematopoietic Cell Transplantation: Fifth Edition. 1: 16-26. DOI: 10.1002/9781118416426.ch3 |
0.423 |
|
| 2015 |
Wang YH, Scadden DT. Targeting the Warburg effect for leukemia therapy: Magnitude matters. Molecular & Cellular Oncology. 2: e981988. PMID 27308458 DOI: 10.4161/23723556.2014.981988 |
0.448 |
|
| 2015 |
Mercier FE, Scadden DT. Not All Created Equal: Lineage Hard-Wiring in the Production of Blood. Cell. 163: 1568-70. PMID 26687347 DOI: 10.1016/J.Cell.2015.12.013 |
0.418 |
|
| 2015 |
Krause DS, Scadden DT. A hostel for the hostile: the bone marrow niche in hematologic neoplasms. Haematologica. 100: 1376-87. PMID 26521296 DOI: 10.3324/Haematol.2014.113852 |
0.488 |
|
| 2015 |
Yu VW, Lymperi S, Ferraro F, Scadden DT. Transcriptome comparison of distinct osteolineage subsets in the hematopoietic stem cell niche using a triple fluorescent transgenic mouse model. Genomics Data. 5: 318-9. PMID 26484277 DOI: 10.1016/J.Gdata.2015.06.001 |
0.471 |
|
| 2015 |
Yu VW, Scadden DT. Global transcriptome analysis of T-competent progenitors in the bone marrow. Genomics Data. 5: 100-2. PMID 26484235 DOI: 10.1016/J.Gdata.2015.05.024 |
0.468 |
|
| 2015 |
Ren X, Moser PT, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier FE, Xiong L, Ghawi R, Scadden DT, Mathisen DJ, Ott HC. Engineering pulmonary vasculature in decellularized rat and human lungs. Nature Biotechnology. PMID 26368048 DOI: 10.1038/Nbt.3354 |
0.339 |
|
| 2015 |
Wang YH, Scadden DT. Harnessing the apoptotic programs in cancer stem-like cells. Embo Reports. PMID 26253117 DOI: 10.15252/Embr.201439675 |
0.404 |
|
| 2015 |
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, ... ... Scadden DT, et al. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 16: 477-87. PMID 25957903 DOI: 10.1016/J.Stem.2015.04.008 |
0.44 |
|
| 2015 |
Yu VW, Saez B, Cook C, Lotinun S, Pardo-Saganta A, Wang YH, Lymperi S, Ferraro F, Raaijmakers MH, Wu JY, Zhou L, Rajagopal J, Kronenberg HM, Baron R, Scadden DT. Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. The Journal of Experimental Medicine. 212: 759-74. PMID 25918341 DOI: 10.1084/Jem.20141843 |
0.494 |
|
| 2015 |
Wang W, Yu S, Zimmerman G, Wang Y, Myers J, Yu VW, Huang D, Huang X, Shim J, Huang Y, Xin W, Qiao P, Yan M, Xin W, Scadden DT, et al. Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention. Stem Cells (Dayton, Ohio). 33: 2280-93. PMID 25851125 DOI: 10.1002/Stem.2031 |
0.409 |
|
| 2015 |
Kfoury Y, Scadden DT. Mesenchymal cell contributions to the stem cell niche. Cell Stem Cell. 16: 239-53. PMID 25748931 DOI: 10.1016/J.Stem.2015.02.019 |
0.547 |
|
| 2015 |
Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, ... ... Scadden DT, et al. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell Reports. PMID 25660025 DOI: 10.1016/J.Celrep.2015.01.017 |
0.411 |
|
| 2015 |
Méndez-Ferrer S, Scadden DT, Sánchez-Aguilera A. Bone marrow stem cells: current and emerging concepts. Annals of the New York Academy of Sciences. 1335: 32-44. PMID 25573321 DOI: 10.1111/Nyas.12641 |
0.533 |
|
| 2015 |
Courties G, Herisson F, Sager HB, Heidt T, Ye Y, Wei Y, Sun Y, Severe N, Dutta P, Scharff J, Scadden DT, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M. Ischemic stroke activates hematopoietic bone marrow stem cells. Circulation Research. 116: 407-17. PMID 25362208 DOI: 10.1161/Circresaha.116.305207 |
0.356 |
|
| 2015 |
Scadden DT. Heterogeneity in the Making of Blood Blood. 126. DOI: 10.1182/Blood.V126.23.Sci-27.Sci-27 |
0.549 |
|
| 2015 |
Itkin T, Gur Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Jung Y, Ledergor G, Milo I, Poulos MG, Fernandez MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, ... ... Scadden DT, et al. Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells Blood. 126: 664-664. DOI: 10.1182/Blood.V126.23.664.664 |
0.516 |
|
| 2015 |
Silberstein L, Kharchenko PV, Kfoury YS, Mercier F, Turcotte R, Lin CP, Baryawno N, Severe N, Tate T, Hoggatt J, Scadden DT. Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells Blood. 126: 663-663. DOI: 10.1182/Blood.V126.23.663.663 |
0.559 |
|
| 2015 |
Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Mansour MK, Scadden DT. Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation Blood. 126: 32-32. DOI: 10.1182/Blood.V126.23.32.32 |
0.447 |
|
| 2015 |
Rasmussen HK, Wong F, Tate T, Scadden DT, Hoggatt J. Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment Blood. 126: 31-31. DOI: 10.1182/Blood.V126.23.31.31 |
0.454 |
|
| 2014 |
Kfoury Y, Scadden DT. Cellular thrust and parry in the leukemic niche. Blood. 124: 2760-1. PMID 25359983 DOI: 10.1182/Blood-2014-09-597716 |
0.343 |
|
| 2014 |
Velardi E, Tsai JJ, Holland AM, Wertheimer T, Yu VW, Zakrzewski JL, Tuckett AZ, Singer NV, West ML, Smith OM, Young LF, Kreines FM, Levy ER, Boyd RL, Scadden DT, et al. Sex steroid blockade enhances thymopoiesis by modulating Notch signaling. The Journal of Experimental Medicine. 211: 2341-9. PMID 25332287 DOI: 10.1182/Blood.V122.21.291.291 |
0.366 |
|
| 2014 |
Wang YH, Israelsen WJ, Lee D, Yu VW, Jeanson NT, Clish CB, Cantley LC, Vander Heiden MG, Scadden DT. Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis. Cell. 158: 1309-23. PMID 25215489 DOI: 10.1016/J.Cell.2014.07.048 |
0.799 |
|
| 2014 |
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, ... ... Scadden DT, et al. Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning. Blood. 124: 2937-47. PMID 25202142 DOI: 10.1182/Blood-2014-08-593426 |
0.533 |
|
| 2014 |
Kalaitzidis D, Scadden DT. Deep diving in the blood stem cell-ome. The Embo Journal. 33: 2281-2. PMID 25190519 DOI: 10.15252/Embj.201489778 |
0.525 |
|
| 2014 |
Choi YJ, Saez B, Anders L, Hydbring P, Stefano J, Bacon NA, Cook C, Kalaszczynska I, Signoretti S, Young RA, Scadden DT, Sicinski P. D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL. Developmental Cell. 30: 255-67. PMID 25087893 DOI: 10.1016/J.Devcel.2014.06.015 |
0.365 |
|
| 2014 |
Baryawno N, Scadden DT. Blood loses it when nerves go bad. Cell Research. 24: 1151-2. PMID 25070156 DOI: 10.1038/Cr.2014.98 |
0.445 |
|
| 2014 |
Kfoury Y, Mercier F, Scadden DT. SnapShot: The hematopoietic stem cell niche. Cell. 158: 228-228.e1. PMID 24995988 DOI: 10.1016/J.Cell.2014.06.019 |
0.507 |
|
| 2014 |
Cho J, Yusuf R, Kook S, Attar E, Lee D, Park B, Cheng T, Scadden DT, Lee BC. Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence. The Journal of Clinical Investigation. 124: 3159-71. PMID 24937426 DOI: 10.1172/Jci61636 |
0.497 |
|
| 2014 |
Park D, Spencer JA, Lin CP, Scadden DT. Sequential in vivo imaging of osteogenic stem/progenitor cells during fracture repair. Journal of Visualized Experiments : Jove. PMID 24894331 DOI: 10.3791/51289 |
0.459 |
|
| 2014 |
Kharchenko PV, Silberstein L, Scadden DT. Bayesian approach to single-cell differential expression analysis. Nature Methods. 11: 740-2. PMID 24836921 DOI: 10.1038/Nmeth.2967 |
0.372 |
|
| 2014 |
Kalaitzidis D, Scadden DT. Tic-TACs: refreshing hair growth. Cell. 157: 769-70. PMID 24813602 DOI: 10.1016/J.Cell.2014.04.014 |
0.482 |
|
| 2014 |
Scadden DT. Nice neighborhood: emerging concepts of the stem cell niche. Cell. 157: 41-50. PMID 24679525 DOI: 10.1016/J.Cell.2014.02.013 |
0.47 |
|
| 2014 |
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 508: 269-73. PMID 24590072 DOI: 10.1038/Nature13034 |
0.497 |
|
| 2014 |
Schajnovitz A, Scadden DT. Bone's dark side: mutated osteoblasts implicated in leukemia. Cell Research. 24: 383-4. PMID 24589711 DOI: 10.1038/Cr.2014.26 |
0.408 |
|
| 2014 |
Li X, Romain RD, Park D, Scadden DT, Merchant JL, Arnaout MA. Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89. Stem Cells (Dayton, Ohio). 32: 791-801. PMID 24549639 DOI: 10.1002/Stem.1598 |
0.461 |
|
| 2014 |
Morrison SJ, Scadden DT. The bone marrow niche for haematopoietic stem cells. Nature. 505: 327-34. PMID 24429631 DOI: 10.1038/Nature12984 |
0.536 |
|
| 2014 |
Silberstein L, Kharchenko P, Kfoury Y, Mercier F, Osawa M, Hoggatt J, Tate T, Lin C, Scadden DT. Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors Blood. 124: 773-773. DOI: 10.1182/Blood.V124.21.773.773 |
0.434 |
|
| 2014 |
Zhou L, Wang W, Zimmerman G, Myers J, Huang Y, Yu VW, Huang D, Yu S, Wang Y, Huang X, Shim J, Yan M, Lowe J, Xin W, Stanley P, ... Scadden DT, et al. Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization Blood. 124: 652-652. DOI: 10.1182/Blood.V124.21.652.652 |
0.454 |
|
| 2014 |
Meister M, Spencer JA, Wu J, Zhao C, Stefania L, Ferraro F, Lo Celso C, Scadden DT, Van Etten RA, Lin C, Krause DS. The Microanatomy of the Leukemic Stem Cell Niche in Murine Chronic Myelogenous Leukemia Blood. 124: 351-351. DOI: 10.1182/Blood.V124.21.351.351 |
0.531 |
|
| 2014 |
Mishima Y, Moschetta M, Shi J, Mercier F, Manier S, Glavey S, Reagan MR, Kawano Y, Munshi NC, Anderson KC, Roccaro AM, Hide W, Scadden DT, Ghobrial IM. Clonal-Heterogeneity and Propensity for Bone Metastasis in Multiple Myeloma Blood. 124: 3370-3370. DOI: 10.1182/Blood.V124.21.3370.3370 |
0.399 |
|
| 2014 |
Mercier F, Shi J, Sykes D, Kfoury YS, Yusuf RZ, Miller E, Vasic R, Zhu A, Michor F, Hide W, Scadden DT. Identification of a Gene Expression Signature Characterizing Clonal Fitness and Dominance in Vivo in a Murine Model of MLL-AF9 Leukemia Blood. 124: 2383-2383. DOI: 10.1182/Blood.V124.21.2383.2383 |
0.455 |
|
| 2014 |
Chattopadhyay S, Huang C, Mukherjee S, Yusuf RZ, Viswanathan V, Wittner BS, Gentry J, Shamji A, Ramaswamy S, Scadden DT, Schreiber SL. Abstract 181: Therapeutic approaches to metastasis induced by mesenchymal stem cells in the tumor microenvironment Cancer Research. 74: 181-181. DOI: 10.1158/1538-7445.Am2014-181 |
0.402 |
|
| 2014 |
Sykes D, Kfoury Y, Blanco A, Scadden D. Phenotypic screening identifies prostacyclin agonists as differentiation agents in the treatment of acute myeloid leukemia Experimental Hematology. 42: S25. DOI: 10.1016/J.Exphem.2014.07.085 |
0.465 |
|
| 2013 |
Sykes SM, Scadden DT. Modeling human hematopoietic stem cell biology in the mouse. Seminars in Hematology. 50: 92-100. PMID 24216169 DOI: 10.1053/J.Seminhematol.2013.03.029 |
0.478 |
|
| 2013 |
Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Diruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, ... ... Scadden DT, et al. Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia. Cancer Cell. 24: 575-88. PMID 24183681 DOI: 10.1016/J.Ccr.2013.09.018 |
0.329 |
|
| 2013 |
Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT. Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nature Medicine. 19: 1513-7. PMID 24162813 DOI: 10.1038/Nm.3364 |
0.515 |
|
| 2013 |
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, ... ... Scadden DT, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nature Chemical Biology. 9: 840-8. PMID 24161946 DOI: 10.1038/Nchembio.1367 |
0.496 |
|
| 2013 |
Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Scadden DT, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177 |
0.41 |
|
| 2013 |
Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP. Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label. Plos One. 8: e69257. PMID 23990881 DOI: 10.1371/Journal.Pone.0069257 |
0.446 |
|
| 2013 |
Samuel R, Daheron L, Liao S, Vardam T, Kamoun WS, Batista A, Buecker C, Schäfer R, Han X, Au P, Scadden DT, Duda DG, Fukumura D, Jain RK. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12774-9. PMID 23861493 DOI: 10.1073/Pnas.1310675110 |
0.45 |
|
| 2013 |
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, ... ... Scadden DT, et al. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 24: 45-58. PMID 23770013 DOI: 10.1016/J.Ccr.2013.05.004 |
0.449 |
|
| 2013 |
Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, ... ... Scadden DT, et al. Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature. 495: 365-9. PMID 23485965 DOI: 10.1038/Nature11929 |
0.498 |
|
| 2013 |
Roccaro AM, Sacco A, Maiso P, Azab AK, Tai YT, Reagan M, Azab F, Flores LM, Campigotto F, Weller E, Anderson KC, Scadden DT, Ghobrial IM. BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. The Journal of Clinical Investigation. 123: 1542-55. PMID 23454749 DOI: 10.1172/Jci66517 |
0.433 |
|
| 2013 |
Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT. Xist RNA is a potent suppressor of hematologic cancer in mice. Cell. 152: 727-42. PMID 23415223 DOI: 10.1016/J.Cell.2013.01.034 |
0.31 |
|
| 2013 |
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D. SIRT3 reverses aging-associated degeneration. Cell Reports. 3: 319-27. PMID 23375372 DOI: 10.1016/J.Celrep.2013.01.005 |
0.347 |
|
| 2013 |
Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin. Embo Molecular Medicine. 5: 430-40. PMID 23364955 DOI: 10.1002/Emmm.201201606 |
0.439 |
|
| 2013 |
Pozzi S, Fulciniti M, Yan H, Vallet S, Eda H, Patel K, Santo L, Cirstea D, Hideshima T, Schirtzinge L, Kuhstoss S, Anderson KC, Munshi N, Scadden D, Kronenberg HM, et al. In vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma. Bone. 53: 487-96. PMID 23333523 DOI: 10.1016/J.Bone.2013.01.012 |
0.35 |
|
| 2013 |
Krause DS, Scadden DT, Preffer FI. The hematopoietic stem cell niche--home for friend and foe? Cytometry. Part B, Clinical Cytometry. 84: 7-20. PMID 23281119 DOI: 10.1002/Cyto.B.21066 |
0.486 |
|
| 2013 |
Fulzele K, Krause DS, Panaroni C, Saini V, Barry KJ, Liu X, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Wu JY, Kronenberg HM, Scadden DT, et al. Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood. 121: 930-9. PMID 23160461 DOI: 10.1182/Blood-2012-06-437160 |
0.479 |
|
| 2013 |
Van Etten RA, Mauro M, Radich JP, Goldman JM, Saglio G, Jamieson C, Soverini S, Gambacorti-Passerini C, Hehlmann R, Martinelli G, Perrotti D, Scadden DT, Skorski T, Tefferi A, Mughal TI. Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop. Leukemia & Lymphoma. 54: 1151-8. PMID 23121619 DOI: 10.3109/10428194.2012.745524 |
0.314 |
|
| 2013 |
Schajnovitz A, Kalinkovich A, Lapid K, Berchanski A, Itkin T, Ludin A, Gur-Cohen S, Golan K, Saez B, Kollet O, Ahrens K, Proksch E, Lapidot A, Fridkin M, Scadden DT, et al. Human and Murine β-Defensin-Derived Peptides Induce Rapid Mobilization Of Murine Hematopoietic Stem and Progenitor Cells Via Activation Of CXCR4 Signaling and CXCL12 Release Blood. 122: 890-890. DOI: 10.1182/Blood.V122.21.890.890 |
0.414 |
|
| 2013 |
Wang Y, Israelsen WJ, Lee D, Yu VW, Jeanson NT, Clish CB, Cantley LC, Vander Heiden MG, Scadden DT. Differential Dependence On Aerobic Glycolysis In Normal and Malignant Hematopoietic Stem and Progenitor Cells To Sustain Daughter Cell Production Blood. 122: 793-793. DOI: 10.1182/Blood.V122.21.793.793 |
0.832 |
|
| 2013 |
Khan S, Stewart AL, Mukherjee S, Scheiber SL, Ebert BL, Golub TR, Scadden DT, Moore MA. Ex Vivo expansion Of Umbilical Cord Blood CD34+ Cells Under Hypoxic Conditions Using Novel Compound#999 With Cytokines Blood. 122: 4508-4508. DOI: 10.1182/Blood.V122.21.4508.4508 |
0.484 |
|
| 2013 |
Palchaudhuri R, Ang K, Saez B, Sykes DB, Verdine GL, Scadden DT. Differentiation Induction In Acute Myeloid Leukemia Using Site-Specific DNA-Targeting Blood. 122: 3940-3940. DOI: 10.1182/Blood.V122.21.3940.3940 |
0.365 |
|
| 2013 |
Krause DS, Lazarides K, Lewis JB, von Andrian UH, Scadden DT, Van Etten RA. BCR-ABL1+ Leukemic Stem Cells Are Dependent On Selectin-Ligand Interactions For Engraftment In The Bone Marrow Niche Blood. 122: 2703-2703. DOI: 10.1182/Blood.V122.21.2703.2703 |
0.532 |
|
| 2013 |
Park D, Hoggatt J, Ferraro F, Scadden DT. The Skeletal Stem Cell Osteoporosis: Fourth Edition. 127-147. DOI: 10.1016/B978-0-12-415853-5.00007-8 |
0.422 |
|
| 2013 |
Cheng T, Scadden DT. Cell Cycle Regulators in Stem Cells Essentials of Stem Cell Biology: Third Edition. 95-106. DOI: 10.1016/B978-0-12-409503-8.00008-1 |
0.437 |
|
| 2013 |
Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. Corrigendum to SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin [EMBO Mol Med] DOI:10.1002/emmm.201201606 Embo Molecular Medicine. 5: 482. DOI: 10.1002/Emmm.201390004 |
0.405 |
|
| 2012 |
Yusuf RZ, Scadden DT. Fate through fat: lipid metabolism determines stem cell division outcome. Cell Metabolism. 16: 411-3. PMID 23040066 DOI: 10.1016/J.Cmet.2012.09.011 |
0.471 |
|
| 2012 |
Kalaitzidis D, Sykes SM, Wang Z, Punt N, Tang Y, Ragu C, Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D, Gilliland DG, Scadden DT, Guertin DA, Armstrong SA. mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell. 11: 429-39. PMID 22958934 DOI: 10.1016/j.stem.2012.06.009 |
0.395 |
|
| 2012 |
Hoggatt J, Scadden DT. The stem cell niche: tissue physiology at a single cell level. The Journal of Clinical Investigation. 122: 3029-34. PMID 22945635 DOI: 10.1172/Jci60238 |
0.454 |
|
| 2012 |
Scadden DT. Rethinking stroma: lessons from the blood. Cell Stem Cell. 10: 648-9. PMID 22704500 DOI: 10.1016/J.Stem.2012.05.011 |
0.447 |
|
| 2012 |
Yusuf RZ, Wang YH, Scadden DT. The secrets of the bone marrow niche: Metabolic priming for AML. Nature Medicine. 18: 865-7. PMID 22673998 DOI: 10.1038/Nm.2831 |
0.371 |
|
| 2012 |
Krause DS, Scadden DT. Deconstructing the complexity of a microenvironmental niche. Cell. 149: 16-7. PMID 22464318 DOI: 10.1016/J.Cell.2012.03.005 |
0.353 |
|
| 2012 |
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell. 10: 259-72. PMID 22385654 DOI: 10.1016/J.Stem.2012.02.003 |
0.513 |
|
| 2012 |
Scadden D, Srivastava A. Advancing stem cell biology toward stem cell therapeutics. Cell Stem Cell. 10: 149-50. PMID 22305564 DOI: 10.1016/J.Stem.2012.01.010 |
0.472 |
|
| 2012 |
Park D, Sykes DB, Scadden DT. The hematopoietic stem cell niche. Frontiers in Bioscience (Landmark Edition). 17: 30-9. PMID 22201730 DOI: 10.2741/3913 |
0.492 |
|
| 2012 |
Mercier FE, Ragu C, Scadden DT. The bone marrow at the crossroads of blood and immunity. Nature Reviews. Immunology. 12: 49-60. PMID 22193770 DOI: 10.1038/Nri3132 |
0.509 |
|
| 2012 |
Bungartz G, Land H, Scadden DT, Emerson SG. NF-Y is necessary for hematopoietic stem cell proliferation and survival. Blood. 119: 1380-9. PMID 22072554 DOI: 10.1182/Blood-2011-06-359406 |
0.371 |
|
| 2012 |
Adams G, Scadden D. Defining the hematopoietic stem cell niche. Discovery Medicine. 4: 118-9. PMID 20705006 |
0.388 |
|
| 2012 |
Saez B, Ferraro F, Yusuf RZ, Cook CM, Sykes SM, Pardo A, Yu VW, Lotinun S, Palchaudhuri R, Lee D, Lymperi S, Day R, Vasic R, Acharya SS, Baron R, ... ... Scadden DT, et al. Hematopoietic Stem/Progenitor Cell Retention in the Bone Marrow Depends On Tissue Specific Heparan Sulfate Proteoglycans Blood. 120: 637-637. DOI: 10.1182/Blood.V120.21.637.637 |
0.565 |
|
| 2012 |
Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Carmody L, Yusuf RZ, Sykes DB, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Cheah J, ... ... Scadden DT, et al. Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma Blood. 120: 571-571. DOI: 10.1182/Blood.V120.21.571.571 |
0.411 |
|
| 2012 |
Sykes DB, Haynes MK, Tolliday N, Waller A, Cobert JM, Szekely BA, Hasaka TP, Sklar L, Zon LI, Scadden DT. Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia Blood. 120: 3513-3513. DOI: 10.1182/Blood.V120.21.3513.3513 |
0.476 |
|
| 2012 |
Yusuf RZ, Acharya SS, Yu VW, Saez B, Cobert JM, Doench J, Bullinger L, S'aulis D, Lee D, Palchaudhuri R, Uzosike AC, Duvet M, Logan DJ, Das S, Cook CM, ... ... Scadden DT, et al. Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells Blood. 120: 208-208. DOI: 10.1182/Blood.V120.21.208.208 |
0.473 |
|
| 2011 |
Lo Celso C, Scadden DT. The haematopoietic stem cell niche at a glance. Journal of Cell Science. 124: 3529-35. PMID 22083139 DOI: 10.1242/Jcs.074112 |
0.461 |
|
| 2011 |
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, ... ... Scadden DT, et al. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Science Translational Medicine. 3: 104ra101. PMID 21998408 DOI: 10.1126/Scitranslmed.3002191 |
0.459 |
|
| 2011 |
Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Schöll C, Tothova Z, Attar EC, ... ... Scadden DT, et al. AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell. 146: 697-708. PMID 21884932 DOI: 10.1016/J.Cell.2011.07.032 |
0.377 |
|
| 2011 |
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Differential niche and Wnt requirements during acute myeloid leukemia progression Blood. 118: 2849-2856. PMID 21765021 DOI: 10.1182/Blood-2011-03-345165 |
0.481 |
|
| 2011 |
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 474: 216-9. PMID 21654805 DOI: 10.1038/Nature10160 |
0.511 |
|
| 2011 |
Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez CK, Rivera-Muñoz P, Rameau P, Tothova Z, Aster JC, DePinho RA, Scadden DT, Gilliland DG, Mercher T. Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification. Blood. 118: 1264-73. PMID 21653327 DOI: 10.1182/Blood-2011-01-328567 |
0.43 |
|
| 2011 |
Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA. Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 9607-12. PMID 21606370 DOI: 10.1073/Pnas.1102018108 |
0.528 |
|
| 2011 |
Vallet S, Pozzi S, Patel K, Vaghela N, Fulciniti MT, Veiby P, Hideshima T, Santo L, Cirstea D, Scadden DT, Anderson KC, Raje N. A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function. Leukemia. 25: 1174-81. PMID 21403648 DOI: 10.1038/Leu.2011.43 |
0.406 |
|
| 2011 |
Vunjak-Novakovic G, Scadden DT. Biomimetic platforms for human stem cell research. Cell Stem Cell. 8: 252-61. PMID 21362565 DOI: 10.1016/J.Stem.2011.02.014 |
0.41 |
|
| 2011 |
Lo Celso C, Lin CP, Scadden DT. In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nature Protocols. 6: 1-14. PMID 21212779 DOI: 10.1038/Nprot.2010.168 |
0.497 |
|
| 2011 |
Hartwell KA, Miller PG, Stewart AL, Kahn AR, Logan DJ, Negri J, Duvet M, Chattopadhyay S, Shterental S, Chu LP, Shieh JH, Jaeraas M, Dancik V, Narayan R, Huang C, ... ... Scadden DT, et al. Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics Blood. 118: 760-760. DOI: 10.1182/Blood.V118.21.760.760 |
0.525 |
|
| 2011 |
Yusuf RZ, Acharya SS, Yu V, Saez B, Duvet M, Scadden E, Warraich G, Clish C, Churchill M, Doench J, Logan DJ, Cook C, Das S, Brown A, Sykes SM, ... ... Scadden DT, et al. Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model Blood. 118: 759-759. DOI: 10.1182/Blood.V118.21.759.759 |
0.45 |
|
| 2011 |
Silberstein L, Osawa M, Lin C, Kharchenko P, Celso CL, Aribeana C, Scadden DT. Real-Time RT-PCR Analysis of Individual Osteolineage Cells within the Hematopoietic Stem Cell Niche Blood. 118: 2389-2389. DOI: 10.1182/Blood.V118.21.2389.2389 |
0.523 |
|
| 2011 |
Krause DS, Fulzele K, Barry K, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Bouxsein M, Scadden DT, Divieti-Pajevic P. Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling Blood. 118: 219-219. DOI: 10.1182/Blood.V118.21.219.219 |
0.464 |
|
| 2011 |
Krause DS, Fulzele K, Catic A, Hurley M, Lezeau S, Hasserjian R, Wu J, Divieti-Pajevic P, Van Etten RA, Schipani E, Scadden DT. Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway Blood. 118: 1670-1670. DOI: 10.1182/Blood.V118.21.1670.1670 |
0.485 |
|
| 2011 |
Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar EC, Fröhling S, ... ... Scadden DT, et al. Erratum: AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias (Cell (2011) 146 (697-708)) Cell. 147. DOI: 10.1016/J.Cell.2011.09.015 |
0.407 |
|
| 2010 |
Ferraro F, Celso CL, Scadden D. Adult stem cels and their niches. Advances in Experimental Medicine and Biology. 695: 155-68. PMID 21222205 DOI: 10.1007/978-1-4419-7037-4_11 |
0.481 |
|
| 2010 |
Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, Tzatsos A, Ozsolak F, Milos P, Ferrari F, Park PJ, Shirihai OS, Scadden DT, Bardeesy N. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature. 468: 659-63. PMID 21124451 DOI: 10.1038/Nature09572 |
0.492 |
|
| 2010 |
Guo S, Scadden DT. A microRNA regulating adult hematopoietic stem cells. Cell Cycle (Georgetown, Tex.). 9: 3637-8. PMID 20855952 DOI: 10.4161/Cc.9.18.13174 |
0.519 |
|
| 2010 |
Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 466: 829-34. PMID 20703299 DOI: 10.1038/Nature09262 |
0.519 |
|
| 2010 |
Lane AA, Scadden DT. Stem cells and DNA damage: persist or perish? Cell. 142: 360-2. PMID 20691895 DOI: 10.1016/J.Cell.2010.07.030 |
0.38 |
|
| 2010 |
Jeanson NT, Scadden DT. Vitamin D receptor deletion leads to increased hematopoietic stem and progenitor cells residing in the spleen. Blood. 116: 4126-9. PMID 20664059 DOI: 10.1182/Blood-2010-04-280552 |
0.813 |
|
| 2010 |
Guo S, Lu J, Schlanger R, Zhang H, Wang JY, Fox MC, Purton LE, Fleming HH, Cobb B, Merkenschlager M, Golub TR, Scadden DT. MicroRNA miR-125a controls hematopoietic stem cell number. Proceedings of the National Academy of Sciences of the United States of America. 107: 14229-34. PMID 20616003 DOI: 10.1073/Pnas.0913574107 |
0.384 |
|
| 2010 |
Lymperi S, Ferraro F, Scadden DT. The HSC niche concept has turned 31. Has our knowledge matured? Annals of the New York Academy of Sciences. 1192: 12-8. PMID 20392212 DOI: 10.1111/J.1749-6632.2009.05223.X |
0.519 |
|
| 2010 |
Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayashi T, Schoonmaker JA, Ebert BL, Al-Shahrour F, Hasserjian RP, Scadden EO, Aung Z, Matza M, Merkenschlager M, Lin C, Rommens JM, ... Scadden DT, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 464: 852-7. PMID 20305640 DOI: 10.1038/Nature08851 |
0.519 |
|
| 2010 |
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, ... ... Scadden DT, et al. Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 5124-9. PMID 20194748 DOI: 10.1073/Pnas.0911929107 |
0.407 |
|
| 2010 |
Krause DS, Lezeau S, Hurley M, Schipani E, Scadden DT. Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Inhibits the Development of Murine Chronic Myelogenous-Leukemia-Like Disease Blood. 116: 937-937. DOI: 10.1182/Blood.V116.21.937.937 |
0.42 |
|
| 2010 |
Vallet S, Patel K, Cirstea D, Luly K, Pozzi S, Santo L, Eda H, Seehra J, Mahindra A, Scadden DT, Raje N. Lenalidomide In Combination with the Activin Receptor Type II Murine Fc Protein RAP-011: Preclinical Rationale for a Novel Anti-Myeloma Strategy Blood. 116: 4075-4075. DOI: 10.1182/Blood.V116.21.4075.4075 |
0.384 |
|
| 2010 |
Sanchez-Aguilera A, Lee Y, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Adrienne D, Luo HR, Scadden DT, Williams DA. Vav1 Regulates Perivascular Homing, Bone Marrow Retention and Engraftment of Hematopoietic Stem Cells Via SDF1a Signaling Blood. 116: 400-400. DOI: 10.1182/Blood.V116.21.400.400 |
0.481 |
|
| 2010 |
Pozzi S, Cirstea D, Santo L, Nabikejje DM, Patel K, Luly KM, Gharti-Chhetry G, Vallet S, Eda H, Hideshima T, Green SR, Anderson KC, Scadden DT, Raje N. CYC065, a Potent Derivative of Seliciclib Is Active In Multiple Myeloma In Preclinical Studies Blood. 116: 2999-2999. DOI: 10.1182/Blood.V116.21.2999.2999 |
0.394 |
|
| 2010 |
Steinbicker AU, Vonner AJ, Sachidanandan C, Lohmeyer L, Scadden DT, Peterson RT, Bloch KD, Yu PB. Role of BMP Signaling In the Anemia of Chronic Disease Blood. 116: 2043-2043. DOI: 10.1182/Blood.V116.21.2043.2043 |
0.312 |
|
| 2010 |
Lane SW, Sykes SM, Ferraro F, Lin CP, Gilliland DG, Williams DA, Scadden DT, Celso CL. Leukemia stem cells occupy niches that are physically distinct and independent of the normal constraints that apply to hematopoietic stem cells Experimental Hematology. 38. DOI: 10.1016/J.Exphem.2010.07.008 |
0.484 |
|
| 2009 |
Curley MD, Therrien VA, Cummings CL, Sergent PA, Koulouris CR, Friel AM, Roberts DJ, Seiden MV, Scadden DT, Rueda BR, Foster R. CD133 expression defines a tumor initiating cell population in primary human ovarian cancer. Stem Cells (Dayton, Ohio). 27: 2875-83. PMID 19816957 DOI: 10.1002/Stem.236 |
0.35 |
|
| 2009 |
Jones R, Capen DE, Jacobson M, Cohen KS, Scadden DT, Duda DG. VEGFR2+PDGFRbeta+ circulating precursor cells participate in capillary restoration after hyperoxia acute lung injury (HALI). Journal of Cellular and Molecular Medicine. 13: 3720-9. PMID 19426150 DOI: 10.1111/J.1582-4934.2009.00785.X |
0.342 |
|
| 2009 |
Lane SW, Scadden DT, Gilliland DG. The leukemic stem cell niche: current concepts and therapeutic opportunities. Blood. 114: 1150-7. PMID 19401558 DOI: 10.1182/Blood-2009-01-202606 |
0.498 |
|
| 2009 |
Qiu J, Takagi Y, Harada J, Topalkara K, Wang Y, Sims JR, Zheng G, Huang P, Ling Y, Scadden DT, Moskowitz MA, Cheng T. p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions. Stem Cells (Dayton, Ohio). 27: 920-7. PMID 19353520 DOI: 10.1002/Stem.1 |
0.371 |
|
| 2009 |
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT. Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature. 459: 103-7. PMID 19322176 DOI: 10.1038/Nature07859 |
0.808 |
|
| 2009 |
Yusuf RZ, Scadden DT. Homing of hematopoietic cells to the bone marrow. Journal of Visualized Experiments : Jove. PMID 19295497 DOI: 10.3791/1104 |
0.52 |
|
| 2009 |
Wu JY, Scadden DT, Kronenberg HM. Role of the osteoblast lineage in the bone marrow hematopoietic niches. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 759-64. PMID 19257832 DOI: 10.1359/Jbmr.090225 |
0.517 |
|
| 2009 |
Ali N, Karlsson C, Aspling M, Hu G, Hacohen N, Scadden DT, Larsson J. Forward RNAi screens in primary human hematopoietic stem/progenitor cells. Blood. 113: 3690-5. PMID 19188664 DOI: 10.1182/Blood-2008-10-176396 |
0.468 |
|
| 2009 |
Raje N, Hideshima T, Mukherjee S, Raab M, Vallet S, Chhetri S, Cirstea D, Pozzi S, Mitsiades C, Rooney M, Kiziltepe T, Podar K, Okawa Y, Ikeda H, Carrasco R, ... ... Scadden D, et al. Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma. Leukemia. 23: 961-70. PMID 19151776 DOI: 10.1038/Leu.2008.378 |
0.361 |
|
| 2009 |
Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Côté D, Rowe DW, Lin CP, Scadden DT. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 457: 92-6. PMID 19052546 DOI: 10.1038/Nature07434 |
0.545 |
|
| 2009 |
Sanchez-Aguilera A, Lee Y, Lo Celso C, Brumme K, Lin CP, Scadden DT, Williams DA. Regulation of Rho GTPases by the Hematopoietic-Specific Guanine Nucleotide Exchange Factor Vav1 Is Critical for Hematopoietic Stem Cell Retention in the Endosteal Niche and Engraftment. Blood. 114: 80-80. DOI: 10.1182/Blood.V114.22.80.80 |
0.474 |
|
| 2009 |
Vallet S, Patel K, Vaghela N, Fulciniti M, Veiby P, Hideshima T, Pozzi S, Santo L, Mukherjee S, Cirstea D, Scadden DT, Anderson KC, Raje N. CCL3 Impairs Osteoblast Function Via Downregulation of Osteocalcin. Blood. 114: 739-739. DOI: 10.1182/Blood.V114.22.739.739 |
0.418 |
|
| 2009 |
Cornejo MG, Sykes SM, Celso CL, Tothova Z, Aster J, DePinho RA, Scadden DT, Gilliland DG, Mercher T. A Regulatory Network Between Notch and AKT Signaling Pathways Differentially Controls Megakaryocyte Development From Hematopoietic Stem or Committed Progenitor Cells. Blood. 114: 384-384. DOI: 10.1182/Blood.V114.22.384.384 |
0.432 |
|
| 2009 |
Raaijmakers MH, Mukherjee S, Guo S, Kobayashi T, Schoonmaker J, Aung Z, Ebert BL, Al-Shahrour F, Hasserjian RP, Vallet S, Scadden E, Lin CP, Scadden DT. Niche Induced Myelodysplasia and Secondary Hematopoietic Neoplasia Caused by Deletion of Dicer1 in Osteoprogenitor Cells. Blood. 114: 247-247. DOI: 10.1182/Blood.V114.22.247.247 |
0.542 |
|
| 2009 |
Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom A, MacArthur B, Lira S, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS. Coordinated Regulation of Hematopoietic and Mesenchymal Stem Cells in a Bone Marrow Niche. Blood. 114: 2-2. DOI: 10.1182/Blood.V114.22.2.2 |
0.533 |
|
| 2009 |
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Rahemtullah A, Attar EC, Guimaraes AR, Chauhan D, Xie W, Patel C, Schoonmaker J, ... ... Scadden DT, et al. Molecular Sequaele of Activin A-Dependent Osteoblast Inhibition in Myeloma. Blood. 114: 1789-1789. DOI: 10.1182/Blood.V114.22.1789.1789 |
0.418 |
|
| 2009 |
Lane SW, Celso CL, Sykes SM, Shterental S, Paktinat M, Lin CP, Williams DA, Scadden DT, Gilliland DG. Leukemia Stem Cells Are Resistant to In Vivo, Cell Non-Autonomous Wnt Inhibition. Blood. 114: 1025-1025. DOI: 10.1182/Blood.V114.22.1025.1025 |
0.48 |
|
| 2009 |
Vallet S, Mukherjee S, Vaghela N, Pozzi S, Santo L, Cirstea D, Fulciniti M, Rahemtullah A, Attar E, Xie W, Patel C, Schoonmaker J, Weller E, Hideshima T, Munshi N, ... ... Scadden D, et al. B357 Targeting Myeloma Bone Disease via Activin A Inhibition Clinical Lymphoma and Myeloma. 9: S126-S127. DOI: 10.1016/S1557-9190(11)70715-6 |
0.313 |
|
| 2009 |
Pozzi S, Yan H, Vallet, S, Fulciniti M, Vaghela, N, Cirstea D, Santo L, Patel K, Mukherjee S, Hideshima T, Schirtzinger L, Kuhstoss S, Anderson K, ... Scadden D, et al. B203 A New Anti-Dkk-1 Antibody Targeting Myeloma Bone Disease Clinical Lymphoma and Myeloma. 9: S111. DOI: 10.1016/S1557-9190(11)70681-3 |
0.302 |
|
| 2009 |
Lensch MW, Jaenisch R, Scadden D, Daley GQ. Konrad Hochedlinger: ISSCR Outstanding Young Investigator for 2009 Cell Stem Cell. 5: 154-155. DOI: 10.1016/J.Stem.2009.07.010 |
0.401 |
|
| 2009 |
Cheng T, Scadden DT. Cell Cycle Regulators in Adult Stem Cells Essentials of Stem Cell Biology. 81-87. DOI: 10.1016/B978-0-12-374729-7.00009-3 |
0.424 |
|
| 2009 |
Dahéron L, Scadden DT. Generation of Definitive Engraftable Hematopoietic Stem Cells from Human Embryonic Stem Cells Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition. 23-35. DOI: 10.1002/9781444303537.ch4 |
0.38 |
|
| 2009 |
Scadden DT. Stem cell-based medicine Proceedings of the American Philosophical Society. 153: 185-192. |
0.359 |
|
| 2008 |
Scadden DT, Komaroff AL. Will stem cells finally deliver? Newsweek. 152: 57-8. PMID 19105310 |
0.384 |
|
| 2008 |
Raaijmakers MH, Scadden DT. Divided within: heterogeneity within adult stem cell pools. Cell. 135: 1006-8. PMID 19070570 DOI: 10.1016/J.Cell.2008.11.034 |
0.469 |
|
| 2008 |
Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 16976-81. PMID 18957542 DOI: 10.1073/Pnas.0802898105 |
0.379 |
|
| 2008 |
Rodrigues NP, Boyd AS, Fugazza C, May GE, Guo Y, Tipping AJ, Scadden DT, Vyas P, Enver T. GATA-2 regulates granulocyte-macrophage progenitor cell function. Blood. 112: 4862-73. PMID 18840712 DOI: 10.1182/Blood-2008-01-136564 |
0.503 |
|
| 2008 |
Larsson J, Ohishi M, Garrison B, Aspling M, Janzen V, Adams GB, Curto M, McClatchey AI, Schipani E, Scadden DT. Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture. Cell Stem Cell. 3: 221-7. PMID 18682243 DOI: 10.1016/J.Stem.2008.06.005 |
0.532 |
|
| 2008 |
Raaijmakers MHGP, Scadden DT. Evolving concepts on the microenvironmental niche for hematopoietic stem cells Current Opinion in Hematology. 15: 301-306. PMID 18536566 DOI: 10.1097/Moh.0B013E328303E14C |
0.474 |
|
| 2008 |
Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. Cell Stem Cell. 2: 584-94. PMID 18522851 DOI: 10.1016/J.Stem.2008.03.012 |
0.482 |
|
| 2008 |
Orford K, Kharchenko P, Lai W, Dao MC, Worhunsky DJ, Ferro A, Janzen V, Park PJ, Scadden DT. Differential H3K4 methylation identifies developmentally poised hematopoietic genes. Developmental Cell. 14: 798-809. PMID 18477461 DOI: 10.1016/J.Devcel.2008.04.002 |
0.345 |
|
| 2008 |
Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Experimental Hematology. 36: 545-558. PMID 18439488 DOI: 10.1016/J.Exphem.2007.12.012 |
0.441 |
|
| 2008 |
Papayannopoulou T, Scadden DT. Stem-cell ecology and stem cells in motion Blood. 111: 3923-3930. PMID 18398055 DOI: 10.1182/Blood-2007-08-078147 |
0.42 |
|
| 2008 |
Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2: 274-83. PMID 18371452 DOI: 10.1016/J.Stem.2008.01.003 |
0.475 |
|
| 2008 |
Craiu A, Scadden D. Flow electroporation with pulsed electric fields for purging tumor cells. Methods in Molecular Biology (Clifton, N.J.). 423: 301-10. PMID 18370208 DOI: 10.1007/978-1-59745-194-9_22 |
0.444 |
|
| 2008 |
Scadden DT. Circadian rhythms: Stem cells traffic in time Nature. 452: 416-417. PMID 18368105 DOI: 10.1038/452416A |
0.481 |
|
| 2008 |
Kim WJ, Okimoto RA, Purton LE, Goodwin M, Haserlat SM, Dayyani F, Sweetser DA, McClatchey AI, Bernard OA, Look AT, Bell DW, Scadden DT, Haber DA. Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias. Blood. 111: 4716-22. PMID 18299447 DOI: 10.1182/Blood-2007-10-113068 |
0.372 |
|
| 2008 |
Daley GQ, Scadden DT. Prospects for Stem Cell-Based Therapy Cell. 132: 544-548. PMID 18295571 DOI: 10.1016/J.Cell.2008.02.009 |
0.48 |
|
| 2008 |
Friel AM, Sergent PA, Patnaude C, Szotek PP, Oliva E, Scadden DT, Seiden MV, Foster R, Rueda BR. Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells Cell Cycle. 7: 242-249. PMID 18256549 DOI: 10.4161/Cc.7.2.5207 |
0.418 |
|
| 2008 |
Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, ... ... Scadden DT, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. The Journal of Clinical Investigation. 118: 491-504. PMID 18219387 DOI: 10.1172/Jci33102 |
0.5 |
|
| 2008 |
Orford KW, Scadden DT. Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation Nature Reviews Genetics. 9: 115-128. PMID 18202695 DOI: 10.1038/Nrg2269 |
0.496 |
|
| 2008 |
Spitzer TR, Ambinder RF, Lee JY, Kaplan LD, Wachsman W, Straus DJ, Aboulafia DM, Scadden DT. Dose-reduced busulfan, cyclophosphamide, and autologous stem cell transplantation for human immunodeficiency virus-associated lymphoma: AIDS Malignancy Consortium study 020. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 14: 59-66. PMID 18158962 DOI: 10.1016/J.Bbmt.2007.03.014 |
0.321 |
|
| 2008 |
Adams GB, Scadden DT. A niche opportunity for stem cell therapeutics Gene Therapy. 15: 96-99. PMID 18004404 DOI: 10.1038/Sj.Gt.3303063 |
0.523 |
|
| 2008 |
Au P, Daheron LM, Duda DG, Cohen KS, Tyrrell JA, Lanning RM, Fukumura D, Scadden DT, Jain RK. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 111: 1302-5. PMID 17993613 DOI: 10.1182/Blood-2007-06-094318 |
0.317 |
|
| 2008 |
Scadden DT. Live-Animal Tracking of Individual Hematopoietic Stem Cells in Their Niche. Blood. 112: sci-41-sci-41. DOI: 10.1182/Blood.V112.11.Sci-41.Sci-41 |
0.539 |
|
| 2008 |
Vallet S, Mukherjee S, Vaghela N, Pozzi S, Santo L, Cirstea D, Fulciniti M, Rahemtullah A, Attar E, Guimaraes AR, Xie W, Patel C, Schoonmaker J, Weller E, Hideshima T, ... ... Scadden DT, et al. Restoration of Bone Balance Via Activin a Inhibition Results in Anti-Myeloma Activity Blood. 112: 645-645. DOI: 10.1182/Blood.V112.11.645.645 |
0.438 |
|
| 2008 |
Vallet Sa, Vaghela N, Fulciniti M, Veiby P, Hideshima T, Pozzi S, Santo L, Mukherjee S, Cirstea D, Scadden DT, Anderson KC, Raje N. CCR1 Inhibition Targets Osteoclast-Myeloma Adhesion and Exerts in Vivo Anti-Osteoclast Activity Blood. 112: 2757-2757. DOI: 10.1182/Blood.V112.11.2757.2757 |
0.457 |
|
| 2008 |
Pozzi S, Yan H, Vallet S, Vaghela N, Fulciniti M, Cirstea D, Santo L, Mukherjee S, Hideshima T, Schirtzinger L, Kuhstoss S, Munshi NC, Anderson KC, Scadden D, Raje N. Promoting Osteoblastogenesis Using a Novel Dkk-1 Neutralizing Antibody in the Treatment of Multiple Myeloma Related Bone Disease Blood. 112: 2739-2739. DOI: 10.1182/Blood.V112.11.2739.2739 |
0.424 |
|
| 2008 |
Adams GB, Martin RP, Alley IR, Chabner KT, Cohen KS, Calvi LM, Kronenberg HM, Scadden DT. Erratum: Corrigendum: Therapeutic targeting of a stem cell niche Nature Biotechnology. 26: 241-241. DOI: 10.1038/Nbt0208-241C |
0.453 |
|
| 2007 |
Lo Celso C, Scadden D. Isolation and transplantation of hematopoietic stem cells (HSCs). Journal of Visualized Experiments : Jove. 157. PMID 18830434 DOI: 10.3791/157 |
0.44 |
|
| 2007 |
Celso CL, Klein RJ, Scadden DT. Analysis of the hematopoietic stem cell niche Current Protocols in Stem Cell Biology. PMID 18785177 DOI: 10.1002/9780470151808.Sc02A05S3 |
0.531 |
|
| 2007 |
Purton LE, Scadden DT. Limiting Factors in Murine Hematopoietic Stem Cell Assays Cell Stem Cell. 1: 263-270. PMID 18371361 DOI: 10.1016/J.Stem.2007.08.016 |
0.496 |
|
| 2007 |
Lo Celso C, Scadden DT. Stem Cells Remember Their Grade Cell Stem Cell. 1: 132-134. PMID 18371344 DOI: 10.1016/J.Stem.2007.07.011 |
0.487 |
|
| 2007 |
Scadden DT. The weight of cell identity Journal of Clinical Investigation. 117: 3653-3655. PMID 18060026 DOI: 10.1172/Jci34181 |
0.497 |
|
| 2007 |
Walkley CR, Olsen GH, Dworkin S, Fabb SA, Swann J, McArthur GA, Westmoreland SV, Chambon P, Scadden DT, Purton LE. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell. 129: 1097-110. PMID 17574023 DOI: 10.1016/J.Cell.2007.05.014 |
0.388 |
|
| 2007 |
Duda DG, Cohen KS, Scadden DT, Jain RK. A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood. Nature Protocols. 2: 805-10. PMID 17446880 DOI: 10.1038/Nprot.2007.111 |
0.44 |
|
| 2007 |
Scadden DT. The stem cell niche in health and leukemic disease Best Practice and Research in Clinical Haematology. 20: 19-27. PMID 17336251 DOI: 10.1016/J.Beha.2006.11.001 |
0.511 |
|
| 2007 |
Bihl F, Narayan M, Chisholm JV, Henry LM, Suscovich TJ, Brown EE, Welzel TM, Kaufmann DE, Zaman TM, Dollard S, Martin JN, Wang F, Scadden DT, Kaye KM, Brander C. Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes. Journal of Virology. 81: 4904-8. PMID 17329344 DOI: 10.1128/Jvi.02509-06 |
0.675 |
|
| 2007 |
Wang ZZ, Au P, Chen T, Shao Y, Daheron LM, Bai H, Arzigian M, Fukumura D, Jain RK, Scadden DT. Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo. Nature Biotechnology. 25: 317-8. PMID 17322871 DOI: 10.1038/Nbt1287 |
0.477 |
|
| 2007 |
Zhang J, Scadden DT, Crumpacker CS. Primitive hematopoietic cells resist HIV-1 infection via p21 Waf1/Cip1/Sdi1 Journal of Clinical Investigation. 117: 473-481. PMID 17273559 DOI: 10.1182/Blood.V108.11.490.490 |
0.345 |
|
| 2007 |
Adams GB, Martin RP, Alley IR, Chabner KT, Cohen KS, Calvi LM, Kronenberg HM, Scadden DT. Therapeutic targeting of a stem cell niche. Nature Biotechnology. 25: 238-43. PMID 17237769 DOI: 10.1038/Nbt1281 |
0.519 |
|
| 2007 |
Chen T, Bai H, Shao Y, Arzigian M, Janzen V, Attar E, Xie Y, Scadden DT, Wang ZZ. Stromal cell-derived factor-1/CXCR4 signaling modifies the capillary-like organization of human embryonic stem cell-derived endothelium in vitro. Stem Cells (Dayton, Ohio). 25: 392-401. PMID 17038674 DOI: 10.1634/Stemcells.2006-0145 |
0.384 |
|
| 2007 |
Adams GB, Martin RP, Alley IR, Chabner KT, Cohen KS, Calvi LM, Kronenberg HM, Scadden DT. Erratum: Corrigendum: Therapeutic targeting of a stem cell niche Nature Biotechnology. 25: 944-944. DOI: 10.1038/nbt0807-944b |
0.345 |
|
| 2007 |
Scadden D. 11: Therapeutic Manipulation of the Stem Cell Niche Biology of Blood and Marrow Transplantation. 13: 1396-1397. DOI: 10.1016/J.Bbmt.2007.08.019 |
0.483 |
|
| 2006 |
Aghi M, Cohen KS, Klein RJ, Scadden DT, Chiocca EA. Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes. Cancer Research. 66: 9054-64. PMID 16982747 DOI: 10.1158/0008-5472.Can-05-3759 |
0.39 |
|
| 2006 |
Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature. 443: 421-6. PMID 16957735 DOI: 10.1038/Nature05159 |
0.475 |
|
| 2006 |
Fleming HE, Scadden DT. Embryonic stem cells make human T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 12213-4. PMID 16894150 DOI: 10.1073/Pnas.0605344103 |
0.491 |
|
| 2006 |
Scadden DT. The stem-cell niche as an entity of action Nature. 441: 1075-1079. PMID 16810242 DOI: 10.1038/Nature04957 |
0.496 |
|
| 2006 |
Purton LE, Scadden DT. Osteoclasts eat stem cells out of house and home Nature Medicine. 12: 610-611. PMID 16761001 DOI: 10.1038/Nm0606-610 |
0.509 |
|
| 2006 |
Janzen V, Scadden DT. Stem cells: Good, bad and reformable Nature. 441: 418-419. PMID 16724049 DOI: 10.1038/441418B |
0.5 |
|
| 2006 |
Adams GB, Scadden DT. The hematopoietic stem cell in its place Nature Immunology. 7: 333-337. PMID 16550195 DOI: 10.1038/Ni1331 |
0.502 |
|
| 2006 |
Duda DG, Cohen KS, di Tomaso E, Au P, Klein RJ, Scadden DT, Willett CG, Jain RK. Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 1449-53. PMID 16549839 DOI: 10.1200/Jco.2005.04.2861 |
0.407 |
|
| 2006 |
Robertson P, Means TK, Luster AD, Scadden DT. CXCR4 and CCR5 mediate homing of primitive bone marrow-derived hematopoietic cells to the postnatal thymus. Experimental Hematology. 34: 308-19. PMID 16543065 DOI: 10.1016/J.Exphem.2005.11.017 |
0.507 |
|
| 2006 |
Larsson J, Scadden D. Nervous activity in a stem cell niche. Cell. 124: 253-5. PMID 16439198 DOI: 10.1016/J.Cell.2006.01.006 |
0.502 |
|
| 2006 |
Adams GB, Chabner KT, Alley IR, Olson DP, Szczepiorkowski ZM, Poznansky MC, Kos CH, Pollak MR, Brown EM, Scadden DT. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature. 439: 599-603. PMID 16382241 DOI: 10.1038/Nature04247 |
0.466 |
|
| 2006 |
Duda DG, Cohen KS, Kozin SV, Perentes JY, Fukumura D, Scadden DT, Jain RK. Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. Blood. 107: 2774-6. PMID 16339405 DOI: 10.1182/Blood-2005-08-3210 |
0.385 |
|
| 2006 |
Miyake N, Brun ACM, Magnusson M, Miyake K, Scadden DT, Karlsson S. HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency Stem Cells. 24: 653-661. PMID 16210402 DOI: 10.1634/Stemcells.2005-0328 |
0.471 |
|
| 2006 |
Zhang J, Attar E, Cohen K, Crumpacker C, Scadden D. Silencing p21(Waf1/Cip1/Sdi1) expression increases gene transduction efficiency in primitive human hematopoietic cells. Gene Therapy. 12: 1444-52. PMID 15877047 DOI: 10.1038/Sj.Gt.3302544 |
0.475 |
|
| 2006 |
Duda DG, Cohen KS, Di Tomaso E, Scadden DT, Willett CG, Jain RK. Differential circulation kinetics during antiangiogenic therapy of four distinct blood cell populations expressing endothelial markers Journal of Clinical Oncology. 24: 3038-3038. DOI: 10.1200/Jco.2006.24.18_Suppl.3038 |
0.333 |
|
| 2006 |
Mukherjee S, Raje N, Patel C, Vallet S, Aronson J, Chhetri S, Mitsiades C, Hideshima T, Anderson KC, Scadden DT. Bortezomib Induces Proliferation of Mesenchymal Progenitor Cells and Promotes Differentiation towards Osteoblastic Lineage. Blood. 108: 88-88. DOI: 10.1182/Blood.V108.11.88.88 |
0.527 |
|
| 2006 |
Janzen V, Fleming HE, Waring MT, Milne CD, Scadden DT. Multifunctional Role of Caspase-3 in Regulating Hematopoietic Stem Cells. Blood. 108: 861-861. DOI: 10.1182/Blood.V108.11.861.861 |
0.533 |
|
| 2006 |
Adams GB, Alley IR, Chabner KT, Chung U, Marsters ES, Weinstein LS, Kronenberg HM, Scadden DT. Hematopoietic Stem Cell Engraftment in Bone Marrow Is Dependent upon G s α. Blood. 108: 857-857. DOI: 10.1182/Blood.V108.11.857.857 |
0.468 |
|
| 2006 |
Saito Y, Attar E, Jana S, Dombkowski D, Janzen V, Lee B, Morrison AD, Abuin A, Pickering S, Livi GP, Adams GB, Scadden DT. Nucleotide Receptor P2Y14 Modulates Hematopoietic Stem Cell Response to Tissue Injury Altering Stem Cell Preservation and Tissue Recovery. Blood. 108: 679-679. DOI: 10.1182/Blood.V108.11.679.679 |
0.443 |
|
| 2006 |
Chadburn A, Chen X, Chiu A, Hyjek E, Tam W, Kaplan L, Scadden DT, Knowles DM, Cesarman E. Neither Germinal Center (GC) vs Non-Germinal Center (Non-GC) Phenotype nor FOXP1 Expression Correlate with Outcome in AIDS-Associated Diffuse Large B-Cell Lymphoma (DLBCL): Study of Patients from AIDS Malignancies Consortium Trials 010 and 034. Blood. 108: 2023-2023. DOI: 10.1182/Blood.V108.11.2023.2023 |
0.313 |
|
| 2006 |
Stier S, Forkert R, Scadden D, Ko Y. Constituent components of the hematopoietic stem cell niche Pneumologie. 59. DOI: 10.1055/s-2005-925491 |
0.36 |
|
| 2005 |
Robertson P, Scadden DT. Differentiation and characterization of T cells Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. PMID 18432955 DOI: 10.1002/0471142735.Im22F08S69 |
0.368 |
|
| 2005 |
Dong HY, Scadden DT, De Leval L, Tang Z, Isaacson PG, Harris NL. Plasmablastic lymphoma in HIV-positive patients: An aggressive Epstein-Barr virus-associated extramedullary plasmacytic neoplasm American Journal of Surgical Pathology. 29: 1633-1641. PMID 16327436 DOI: 10.1097/01.Pas.0000173023.02724.1F |
0.339 |
|
| 2005 |
Woodberry T, Suscovich TJ, Henry LM, Davis JK, Frahm N, Walker BD, Scadden DT, Wang F, Brander C. Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection. The Journal of Infectious Diseases. 192: 1513-24. PMID 16206065 DOI: 10.1086/491741 |
0.658 |
|
| 2005 |
Woodberry T, Suscovich TJ, Henry LM, August M, Waring MT, Kaur A, Hess C, Kutok JL, Aster JC, Wang F, Scadden DT, Brander C. Alpha E beta 7 (CD103) expression identifies a highly active, tonsil-resident effector-memory CTL population. Journal of Immunology (Baltimore, Md. : 1950). 175: 4355-62. PMID 16177076 DOI: 10.4049/Jimmunol.175.7.4355 |
0.674 |
|
| 2005 |
Johnson J, Bagley J, Skaznik-Wikiel M, Lee HJ, Adams GB, Niikura Y, Tschudy KS, Tilly JC, Cortes ML, Forkert R, Spitzer T, Iacomini J, Scadden DT, Tilly JL. Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood. Cell. 122: 303-15. PMID 16051153 DOI: 10.1016/J.Cell.2005.06.031 |
0.49 |
|
| 2005 |
Woodberry T, Suscovich TJ, Henry LM, Martin JN, Dollard S, O'Connor PG, Davis JK, Osmond D, Lee TH, Kedes DH, Khatri A, Lee J, Walker BD, Scadden DT, Brander C. Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins. The Journal of Infectious Diseases. 192: 622-9. PMID 16028131 DOI: 10.1086/432103 |
0.647 |
|
| 2005 |
Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. The Journal of Clinical Investigation. 115: 1743-55. PMID 16007251 DOI: 10.1172/Jci22593 |
0.489 |
|
| 2005 |
Sipkins DA, Wei X, Wu JW, Runnels JM, Côté D, Means TK, Luster AD, Scadden DT, Lin CP. In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. Nature. 435: 969-73. PMID 15959517 DOI: 10.1038/Nature03703 |
0.529 |
|
| 2005 |
Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grünewald E, Cheng T, Dombkowski D, Calvi LM, Rittling SR, Scadden DT. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. The Journal of Experimental Medicine. 201: 1781-91. PMID 15928197 DOI: 10.1084/Jem.20041992 |
0.533 |
|
| 2005 |
Rodrigues NP, Janzen V, Forkert R, Dombkowski DM, Boyd AS, Orkin SH, Enver T, Vyas P, Scadden DT. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis Blood. 106: 477-484. PMID 15811962 DOI: 10.1182/Blood-2004-08-2989 |
0.547 |
|
| 2005 |
Li ZJ, Wang ZZ, Zheng YZ, Xu B, Yang RC, Scadden DT, Han ZC. Kinetic expression of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) during embryonic stem cell differentiation Journal of Cellular Biochemistry. 95: 559-570. PMID 15786495 DOI: 10.1002/Jcb.20436 |
0.464 |
|
| 2005 |
Kutok JL, Yang X, Folkerth RD, Imitola J, Raddassi K, Yano Y, Salahuddin S, Lawitts J, Imboden H, Chinami M, Shirakawa T, Turner H, Khoury S, Sayegh MH, Scadden D, et al. The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice. Journal of Molecular Histology. 36: 77-87. PMID 15704002 DOI: 10.1007/S10735-004-3913-8 |
0.411 |
|
| 2005 |
Scadden DT, Feder D, Groopman JE. Scratching the surface. Current Biology : Cb. 1: 301-3. PMID 15336104 DOI: 10.1016/0960-9822(91)90091-A |
0.444 |
|
| 2005 |
Craiu A, Saito Y, Limon A, Eppich HM, Olson DP, Rodrigues N, Adams GB, Dombkowski D, Richardson P, Schlossman R, Choi PS, Grogins J, O'Connor PG, Cohen K, Attar EC, ... ... Scadden DT, et al. Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood. 105: 2235-8. PMID 15292069 DOI: 10.1182/Blood-2003-12-4399 |
0.5 |
|
| 2005 |
Wang ZZ, Chen T, Au P, Shao Y, Jain R, Scadden DT. A Novel Culture System of Human ES Cells for High Efficient Hematopoietic and Endothelial Differentiation. Blood. 106: 3616-3616. DOI: 10.1182/Blood.V106.11.3616.3616 |
0.467 |
|
| 2005 |
Janzen V, Fleming H, Reynolds G, Waring M, Scadden DT. Caspase-3 Has Apoptotic and Non-Apoptotic Functions in Regulating the Fate of Hematopoietic Stem Cells. Blood. 106: 1717-1717. DOI: 10.1182/Blood.V106.11.1717.1717 |
0.506 |
|
| 2005 |
Scadden DT. Adult Stem Cells American Journal of Transplantation. 5: 193-193. DOI: 10.1111/J.1600-6143.2004.00668.X |
0.431 |
|
| 2004 |
Attar EC, Scadden DT. Regulation of hematopoietic stem cell growth Leukemia. 18: 1760-1768. PMID 15457182 DOI: 10.1038/Sj.Leu.2403515 |
0.504 |
|
| 2004 |
Suscovich TJ, Paulose-Murphy M, Harlow JD, Chen Y, Thomas SY, Mellott TJ, Walker BD, Scadden DT, Zeichner S, Brander C. Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles. Leukemia & Lymphoma. 45: 1223-38. PMID 15360006 DOI: 10.1080/10428190310001643358 |
0.709 |
|
| 2004 |
Scadden DT. Cancer stem cells refined Nature Immunology. 5: 701-703. PMID 15224098 DOI: 10.1038/Ni0704-701 |
0.487 |
|
| 2004 |
Chabner KT, Adams GB, Qiu J, Moskowitz M, Marsters ES, Topulos GP, Scadden DT. Direct vascular delivery of primitive hematopoietic cells to bone marrow improves localization but not engraftment Blood. 103: 4685-4686. PMID 15178586 DOI: 10.1182/Blood-2003-12-4145 |
0.467 |
|
| 2004 |
Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nature Cell Biology. 6: 436-42. PMID 15122268 DOI: 10.1038/Ncb1126 |
0.481 |
|
| 2004 |
Qiu J, Takagi Y, Harada J, Rodrigues N, Moskowitz MA, Scadden DT, Cheng T. Regenerative response in ischemic brain restricted by p21cip1/waf1. The Journal of Experimental Medicine. 199: 937-45. PMID 15067031 DOI: 10.1084/Jem.20031385 |
0.425 |
|
| 2004 |
Wang Z, Cohen K, Shao Y, Mole P, Dombkowski D, Scadden DT. Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels. Blood. 103: 100-9. PMID 12958066 DOI: 10.1182/Blood-2003-04-1063 |
0.44 |
|
| 2004 |
Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Gruenewald E, Dombkowski D, Rittling SR, Scadden DT. Matrix Glycoprotein Osteopontin Is a Stem Cell Niche Constituent That Constrains the Hematopoietic Stem Cell Pool Size. Blood. 104: 664-664. DOI: 10.1182/Blood.V104.11.664.664 |
0.541 |
|
| 2004 |
Sipkins DA, Wei X, Wu JW, Means TK, Luster AD, Lin CP, Scadden DT. Specialized Bone Marrow Endothelium Defines Microdomains for Tumor and Stem Cell Engraftment. Blood. 104: 663-663. DOI: 10.1182/Blood.V104.11.663.663 |
0.511 |
|
| 2004 |
Han ZC, Li ZJ, Wang ZZ, Zheng YZ, Xu B, Yang RC, Scadden DT. Unique Expression of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) on Embryonic Stem Cells. Blood. 104: 3914-3914. DOI: 10.1182/Blood.V104.11.3914.3914 |
0.44 |
|
| 2004 |
Miyake N, Brun AC, Magnusson M, Scadden DT, Karlsson S. Hematopoietic Stem Cell Expansion by HOXB4 Is Greatly Enhanced in p21 Deficient Stem Cells. Blood. 104: 1688-1688. DOI: 10.1182/Blood.V104.11.1688.1688 |
0.491 |
|
| 2003 |
Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature. 425: 841-6. PMID 14574413 DOI: 10.1038/Nature02040 |
0.556 |
|
| 2003 |
Scadden DT. Stem cells and immune reconstitution in AIDS Blood Reviews. 17: 227-231. PMID 14556777 DOI: 10.1016/S0268-960X(03)00021-3 |
0.374 |
|
| 2003 |
Lee BC, Cheng T, Adams GB, Attar EC, Miura N, Lee SB, Saito Y, Olszak I, Dombkowski D, Olson DP, Hancock J, Choi PS, Haber DA, Luster AD, Scadden DT. P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells. Genes & Development. 17: 1592-604. PMID 12842911 DOI: 10.1101/Gad.1071503 |
0.491 |
|
| 2003 |
Christmas P, Carlesso N, Shang H, Cheng SM, Weber BM, Preffer FI, Scadden DT, Soberman RJ. Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter. The Journal of Biological Chemistry. 278: 25133-42. PMID 12709424 DOI: 10.1074/Jbc.M302106200 |
0.38 |
|
| 2003 |
Stier S, Cheng T, Forkert R, Lutz C, Dombkowski DM, Zhang JL, Scadden DT. Ex vivo targeting of p21Cip1/Waf1 permits relative expansion of human hematopoietic stem cells. Blood. 102: 1260-6. PMID 12702511 DOI: 10.1182/Blood-2002-10-3053 |
0.513 |
|
| 2003 |
Fukushima T, Miyazaki Y, Tsushima H, Tsutsumi C, Taguchi J, Yoshida S, Kuriyama K, Scadden D, Nimer S, Tomonaga M. The level of MEF but not ELF-1 correlates with FAB subtype of acute myeloid leukemia and is low in good prognosis cases. Leukemia Research. 27: 387-92. PMID 12620289 DOI: 10.1016/S0145-2126(02)00214-X |
0.333 |
|
| 2003 |
Scadden DT. Toward cellular-based therapies for HIV infection. Journal of Hematotherapy & Stem Cell Research. 11: 759-64. PMID 12427282 DOI: 10.1089/152581602760404568 |
0.323 |
|
| 2003 |
Adams GB, Chabner KT, Foxall RB, Weibrecht KW, Rodrigues NP, Dombkowski D, Fallon R, Poznansky MC, Scadden DT. Heterologous cells cooperate to augment stem cell migration, homing, and engraftment. Blood. 101: 45-51. PMID 12393569 DOI: 10.1182/Blood-2002-02-0486 |
0.458 |
|
| 2003 |
Preffer FI, Dombkowski D, Sykes M, Scadden D, Yang YG. Lineage-negative side-population (SP) cells with restricted hematopoietic capacity circulate in normal human adult blood: immunophenotypic and functional characterization. Stem Cells (Dayton, Ohio). 20: 417-27. PMID 12351812 DOI: 10.1634/Stemcells.20-5-417 |
0.457 |
|
| 2003 |
Cheng T, Scadden DT. Cell cycle entry of hematopoietic stem and progenitor cells controlled by distinct cyclin-dependent kinase inhibitors. International Journal of Hematology. 75: 460-5. PMID 12095144 DOI: 10.1007/Bf02982107 |
0.502 |
|
| 2003 |
Scadden DT, Shen H, Cheng T. Hematopoietic stem cells in HIV disease. Journal of the National Cancer Institute. Monographs. 24-9. PMID 11158203 DOI: 10.1093/Oxfordjournals.Jncimonographs.A024253 |
0.414 |
|
| 2002 |
Jiang Z, Adams GB, Hanash AM, Scadden DT, Levy RB. The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 8: 588-96. PMID 12463477 DOI: 10.1053/Bbmt.2002.V8.Abbmt080588 |
0.425 |
|
| 2002 |
Brander C, Raje N, O'Connor PG, Davies F, Davis J, Chauhan D, Hideshima T, Martin J, Osmond D, Kedes DH, Walker BD, Scadden DT, Anderson KC. Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma. Blood. 100: 698-700. PMID 12091368 DOI: 10.1182/Blood.V100.2.698 |
0.327 |
|
| 2002 |
Deeks SG, Wagner B, Anton PA, Mitsuyasu RT, Scadden DT, Huang C, Macken C, Richman DD, Christopherson C, June CH, Lazar R, Broad DF, Jalali S, Hege KM. A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy Molecular Therapy. 5: 788-797. PMID 12027564 DOI: 10.1006/Mthe.2002.0611 |
0.351 |
|
| 2002 |
Poznansky MC, Olszak IT, Evans RH, Wang Z, Foxall RB, Olson DP, Weibrecht K, Luster AD, Scadden DT. Thymocyte emigration is mediated by active movement away from stroma-derived factors. The Journal of Clinical Investigation. 109: 1101-10. PMID 11956248 DOI: 10.1172/Jci13853 |
0.406 |
|
| 2002 |
Wang Z, Miura N, Bonelli A, Mole P, Carlesso N, Olson DP, Scadden DT. Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells. Blood. 99: 2740-7. PMID 11929761 DOI: 10.1182/Blood.V99.8.2740 |
0.532 |
|
| 2002 |
Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood. 99: 2369-78. PMID 11895769 DOI: 10.1182/Blood.V99.7.2369 |
0.486 |
|
| 2002 |
Donato JL, Ko J, Kutok JL, Cheng T, Shirakawa T, Mao XQ, Beach D, Scadden DT, Sayegh MH, Adra CN. Human HTm4 is a hematopoietic cell cycle regulator. The Journal of Clinical Investigation. 109: 51-8. PMID 11781350 DOI: 10.1172/Jci14025 |
0.461 |
|
| 2001 |
Levine AM, Scadden DT, Zaia JA, Krishnan A. Hematologic Aspects of HIV/AIDS Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 463-478. PMID 11722999 DOI: 10.1182/Asheducation-2001.1.463 |
0.357 |
|
| 2001 |
Christmas P, Jones JP, Patten CJ, Rock DA, Zheng Y, Cheng SM, Weber BM, Carlesso N, Scadden DT, Rettie AE, Soberman RJ. Alternative splicing determines the function of CYP4F3 by switching substrate specificity. The Journal of Biological Chemistry. 276: 38166-72. PMID 11461919 DOI: 10.1074/Jbc.M104818200 |
0.314 |
|
| 2001 |
Brander C, O'Connor P, Suscovich T, Jones NG, Lee Y, Kedes D, Ganem D, Martin J, Osmond D, Southwood S, Sette A, Walker BD, Scadden DT. Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. The Journal of Infectious Diseases. 184: 119-26. PMID 11424007 DOI: 10.1086/322003 |
0.644 |
|
| 2001 |
Poznansky MC, Olszak IT, Foxall RB, Piascik A, Adams GB, Evans RH, Cheng T, Scadden DT. Tissue source dictates lineage outcome of human fetal CD34 +CD38 - cells Experimental Hematology. 29: 766-774. PMID 11378272 DOI: 10.1016/S0301-472X(01)00643-9 |
0.47 |
|
| 2001 |
Ellisen LW, Carlesso N, Cheng T, Scadden DT, Haber DA. The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells. The Embo Journal. 20: 1897-909. PMID 11296223 DOI: 10.1093/Emboj/20.8.1897 |
0.46 |
|
| 2001 |
Shen H, Cheng T, Olszak I, Garcia-Zepeda E, Lu Z, Herrmann S, Fallon R, Luster AD, Scadden DT. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 5027-33. PMID 11290783 DOI: 10.4049/Jimmunol.166.8.5027 |
0.486 |
|
| 2000 |
Cheng T, Rodrigues N, Dombkowski D, Stier S, Scadden DT. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nature Medicine. 6: 1235-40. PMID 11062534 DOI: 10.1038/81335 |
0.512 |
|
| 2000 |
Evans RH, Scadden DT. Haematological aspects of HIV infection. Bailliere's Best Practice & Research. Clinical Haematology. 13: 215-30. PMID 10942622 DOI: 10.1053/Beha.1999.0069 |
0.332 |
|
| 2000 |
Eppich HM, Foxall R, Gaynor K, Dombkowski D, Miura N, Cheng T, Silva-Arrieta S, Evans RH, Mangano JA, Preffer FI, Scadden DT. Pulsed electric fields for selection of hematopoietic cells and depletion of tumor cell contaminants. Nature Biotechnology. 18: 882-7. PMID 10932160 DOI: 10.1038/78504 |
0.505 |
|
| 2000 |
Brander C, Suscovich T, Lee Y, Nguyen PT, O'Connor P, Seebach J, Jones NG, van Gorder M, Walker BD, Scadden DT. Impaired CTL recognition of cells latently infected with Kaposi's sarcoma-associated herpes virus. Journal of Immunology (Baltimore, Md. : 1950). 165: 2077-83. PMID 10925292 DOI: 10.4049/Jimmunol.165.4.2077 |
0.668 |
|
| 2000 |
Poznansky MC, Evans RH, Foxall RB, Olszak IT, Piascik AH, Hartman KE, Brander C, Meyer TH, Pykett MJ, Chabner KT, Kalams SA, Rosenzweig M, Scadden DT. Efficient generation of human T cells from a tissue-engineered thymic organoid. Nature Biotechnology. 18: 729-34. PMID 10888839 DOI: 10.1038/77288 |
0.427 |
|
| 2000 |
Poznansky MC, Olszak IT, Foxall R, Evans RH, Luster AD, Scadden DT. Active movement of T cells away from a chemokine. Nature Medicine. 6: 543-8. PMID 10802710 DOI: 10.1038/75022 |
0.423 |
|
| 2000 |
Olszak IT, Poznansky MC, Evans RH, Olson D, Kos C, Pollak MR, Brown EM, Scadden DT. Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo Journal of Clinical Investigation. 105: 1299-1305. PMID 10792005 DOI: 10.1172/Jci9799 |
0.302 |
|
| 2000 |
Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nature Biotechnology. 18: 410-4. PMID 10748521 DOI: 10.1038/74464 |
0.49 |
|
| 2000 |
Podestà M, Zocchi E, Pitto A, Usai C, Franco L, Bruzzone S, Guida L, Bacigalupo A, Scadden DT, Walseth TF, De Flora A, Daga A. Extracellular cyclic ADP-ribose increases intracellular free calcium concentration and stimulates proliferation of human hemopoietic progenitors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 680-90. PMID 10744625 DOI: 10.1096/Fasebj.14.5.680 |
0.383 |
|
| 2000 |
Cheng T, Rodrigues N, Shen H, Yang Y, Dombkowski D, Sykes M, Scadden DT. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science (New York, N.Y.). 287: 1804-8. PMID 10710306 DOI: 10.1126/Science.287.5459.1804 |
0.532 |
|
| 2000 |
Mitsuyasu RT, Anton PA, Deeks SG, Scadden DT, Connick E, Downs MT, Bakker A, Roberts MR, June CH, Jalali S, Lin AA, Pennathur-Das R, Hege KM. Prolonged survival and tissue trafficking following adoptive transfer of CD4ζ gene-modified autologous CD4+ and CD8+ T cells in human immunodeficiency virus–infected subjects Blood. 96: 785-793. DOI: 10.1182/Blood.V96.3.785.015K10_785_793 |
0.359 |
|
| 1999 |
Cavacini LA, Wisnewski A, Peterson JE, Montefiori D, Emes C, Duval M, Kingsbury G, Wang A, Scadden D, Posner MR. A human anti-HIV autoantibody enhances EBV transformation and HIV infection. Clinical Immunology (Orlando, Fla.). 93: 263-73. PMID 10600338 DOI: 10.1006/Clim.1999.4790 |
0.329 |
|
| 1999 |
Scadden DT. Immune reconstitution in AIDS: oncologic implications and hematologic approaches. Current Opinion in Oncology. 11: 503-7. PMID 10550015 DOI: 10.1097/00001622-199911000-00012 |
0.302 |
|
| 1999 |
Poznansky MC, La Vecchio J, Silva-Arietta S, Porter-Brooks J, Brody K, Olszak IT, Adams GB, Ramstedt U, Marasco WA, Scadden DT. Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells and monocytes derived from CD34+ cells transduced with an intracellular antibody directed against human immunodeficiency virus type 1 Tat Human Gene Therapy. 10: 2505-2514. PMID 10543615 DOI: 10.1089/10430349950016843 |
0.426 |
|
| 1999 |
Turnbull JL, Patchen ML, Scadden DT. The polysaccharide, PGG-glucan, enhances human myelopoiesis by direct action independent of and additive to early-acting cytokines. Acta Haematologica. 102: 66-71. PMID 10529508 DOI: 10.1159/000040972 |
0.43 |
|
| 1999 |
Adams GB, McMullen M, Turner S, Olszak IT, Scadden DT, McClure MO, Poznansky MC. Isolation and transduction of CD34+ cells from small quantities of peripheral blood from HIV-1-infected patients not treated with hemopoietic growth factors Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 21: 1-8. PMID 10235508 DOI: 10.1097/00126334-199905010-00001 |
0.361 |
|
| 1999 |
Shen H, Cheng T, Preffer FI, Dombkowski D, Tomasson MH, Golan DE, Yang O, Hofmann W, Sodroski JG, Luster AD, Scadden DT. Intrinsic human immunodeficiency virus type 1 resistance of hematopoietic stem cells despite coreceptor expression. Journal of Virology. 73: 728-37. PMID 9847379 DOI: 10.1128/Jvi.73.1.728-737.1999 |
0.441 |
|
| 1999 |
Carlesso N, Aster JC, Sklar J, Scadden DT. Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics Blood. 93: 838-848. DOI: 10.1182/Blood.V93.3.838 |
0.491 |
|
| 1998 |
Radomska HS, Huettner CS, Zhang P, Cheng T, Scadden DT, Tenen DG. CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Molecular and Cellular Biology. 18: 4301-14. PMID 9632814 DOI: 10.1128/Mcb.18.7.4301 |
0.38 |
|
| 1998 |
Yamaguchi T, Olozak I, Chattopadhyay N, Butters RR, Kifor O, Scadden DT, Brown EM. Expression of extracellular calcium (Ca2+o)-sensing receptor in human peripheral blood monocytes. Biochemical and Biophysical Research Communications. 246: 501-6. PMID 9610391 DOI: 10.1006/Bbrc.1998.8648 |
0.373 |
|
| 1997 |
Scadden DT. Cytokine use in the management of HIV disease. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. S23-9. PMID 9389312 DOI: 10.1097/00042560-199701001-00004 |
0.306 |
|
| 1997 |
Franken M, Estabrooks A, Cavacini L, Sherburne B, Wang F, Scadden DT. Epstein-Barr virus-driven gene therapy for EBV-related lymphomas. Nature Medicine. 2: 1379-82. PMID 8946840 DOI: 10.1038/Nm1296-1379 |
0.382 |
|
| 1997 |
Gardner JP, Zhu H, Colosi PC, Kurtzman GJ, Scadden DT. Robust, But Transient Expression of Adeno-Associated Virus-Transduced Genes During Human T Lymphopoiesis Blood. 90: 4854-4864. DOI: 10.1182/Blood.V90.12.4854 |
0.455 |
|
| 1996 |
Cheng T, Shen H, Giokas D, Gere J, Tenen DG, Scadden DT. Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 93: 13158-13163. PMID 8917561 DOI: 10.1073/Pnas.93.23.13158 |
0.401 |
|
| 1996 |
Freedman AR, Zhu H, Levine JD, Kalams S, Scadden DT. Generation of human T lymphocytes from bone marrow CD34+ cells in vitro. Nature Medicine. 2: 46-51. PMID 8564838 DOI: 10.1038/Nm0196-46 |
0.48 |
|
| 1996 |
Rosenzweig M, Marks D, Zhu H, Hempel D, Mansfield K, Sehgal P, Kalams S, Scadden D, Johnson R. In vitro T lymphopoiesis of human and rhesus CD34+ progenitor cells Blood. 87: 4040-4048. DOI: 10.1182/Blood.V87.10.4040.Bloodjournal87104040 |
0.388 |
|
| 1995 |
Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT. Functional isolation and characterization of human hematopoietic stem cells. Science (New York, N.Y.). 267: 104-8. PMID 7528940 DOI: 10.1126/Science.7528940 |
0.557 |
|
| 1995 |
Price P, Johnson RP, Scadden DT, Jassoy C, Rosenthal T, Kalams S, Walker BD. Cytotoxic CD8+ T lymphocytes reactive with human immunodeficiency virus-1 produce granulocyte/macrophage colony-stimulating factor and variable amounts of interleukins 2, 3, and 4 following stimulation with the cognate epitope. Clinical Immunology and Immunopathology. 74: 100-6. PMID 7527747 DOI: 10.1006/Clin.1995.1014 |
0.337 |
|
| 1995 |
Berardi A, Wang A, Abraham J, Scadden D. Basic fibroblast growth factor mediates its effects on committed myeloid progenitors by direct action and has no effect on hematopoietic stem cells Blood. 86: 2123-2129. DOI: 10.1182/Blood.V86.6.2123.Bloodjournal8662123 |
0.478 |
|
| 1994 |
Scadden DT, Wang A, Zsebo KM, Groopman JE. In vitro effects of stem-cell factor or interleukin-3 on myelosuppression associated with AIDS. Aids (London, England). 8: 193-6. PMID 7519020 DOI: 10.1097/00002030-199402000-00006 |
0.446 |
|
| 1994 |
Avraham H, Banu N, Scadden D, Abraham J, Groopman J. Modulation of megakaryocytopoiesis by human basic fibroblast growth factor Blood. 83: 2126-2132. DOI: 10.1182/Blood.V83.8.2126.2126 |
0.333 |
|
| 1992 |
Avraham H, Scadden D, Chi S, Broudy V, Zsebo K, Groopman J. Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand Blood. 80: 1679-1684. DOI: 10.1182/Blood.V80.7.1679.Bloodjournal8071679 |
0.409 |
|
| 1991 |
Scadden DT, Bering HA, Levine JD, Bresnahan J, Evans L, Epstein C, Groopman JE. Granulocyte-macrophage colony-stimulating factor mitigates the neutropenia of combined interferon alfa and zidovudine treatment of acquired immune deficiency syndrome-associated Kaposi's sarcoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 9: 802-8. PMID 2016623 DOI: 10.1200/Jco.1991.9.5.802 |
0.303 |
|
| 1990 |
Scadden DT, Fuller B, Cunningham JM. Human cells infected with retrovirus vectors acquire an endogenous murine provirus. Journal of Virology. 64: 424-7. PMID 2152828 DOI: 10.1128/Jvi.64.1.424-427.1990 |
0.377 |
|
| 1990 |
Scadden D, Zeira M, Woon A, Wang Z, Schieve L, Ikeuchi K, Lim B, Groopman J. Human immunodeficiency virus infection of human bone marrow stromal fibroblasts Blood. 76: 317-322. DOI: 10.1182/Blood.V76.2.317.Bloodjournal762317 |
0.389 |
|
| 1990 |
Molina J, Scadden D, Sakaguchi M, Fuller B, Woon A, Groopman J. Lack of evidence for infection of or effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus Blood. 76: 2476-2482. DOI: 10.1182/Blood.V76.12.2476.Bloodjournal76122476 |
0.369 |
|
| 1989 |
Groopman JE, Molina JM, Scadden DT. Hematopoietic growth factors. Biology and clinical applications New England Journal of Medicine. 321: 1449-1459. PMID 2682244 DOI: 10.1056/Nejm198911233212106 |
0.37 |
|
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