Year |
Citation |
Score |
2023 |
Bourne N, Keith CA, Miller AL, Pyles RB, Cohen G, Milligan GN. Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease. Journal of Virology. e0066923. PMID 37655939 DOI: 10.1128/jvi.00669-23 |
0.307 |
|
2019 |
Charles DD, Fisher JR, Hoskinson SM, Medina-Colorado AA, Shen YC, Chaaban MR, Widen SG, Eaves-Pyles TD, Maxwell CA, Miller AL, Popov VL, Pyles RB. Development of a Novel Nasal Epithelial Cell Model Supporting Colonization With Human Nasal Microbiota. Frontiers in Cellular and Infection Microbiology. 9: 165. PMID 31165051 DOI: 10.3389/Fcimb.2019.00165 |
0.324 |
|
2018 |
Amerson-Brown MH, Miller AL, Maxwell CA, White MM, Vincent KL, Bourne N, Pyles RB. Cultivated Human Vaginal Microbiome Communities Impact Zika and Herpes Simplex Virus Replication in Vaginal Mucosal Cultures. Frontiers in Microbiology. 9: 3340. PMID 30692980 DOI: 10.3389/Fmicb.2018.03340 |
0.431 |
|
2018 |
Bourne N, Perry CL, Banasik BN, Miller AL, White M, Pyles RB, Schäfer H, Milligan GN. Increased frequency of virus shedding by herpes simplex virus type 2-infected guinea pigs in the absence of CD4+ T lymphocytes. Journal of Virology. PMID 30463981 DOI: 10.1128/Jvi.01721-18 |
0.354 |
|
2018 |
Bourne N, Banasik BN, Perry CL, Miller AL, White M, Pyles RB, Milligan GN. Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2. Virology. 526: 180-188. PMID 30412859 DOI: 10.1016/J.Virol.2018.10.023 |
0.426 |
|
2018 |
Vincent KL, Moss JA, Marzinke MA, Hendrix CW, Anton PA, Gunawardana M, Dawson LN, Olive TJ, Pyles RB, Baum MM. Phase I trial of pod-intravaginal rings delivering antiretroviral agents for HIV-1 prevention: Rectal drug exposure from vaginal dosing with tenofovir disoproxil fumarate, emtricitabine, and maraviroc. Plos One. 13: e0201952. PMID 30133534 DOI: 10.1371/Journal.Pone.0201952 |
0.312 |
|
2018 |
Milligan GN, White M, Zavala D, Pyles RB, Sarathy VV, Barrett ADT, Bourne N. Spectrum of activity testing for therapeutics against all four dengue virus serotypes in AG129 mouse models: Proof-of-concept studies with the adenosine nucleoside inhibitor NITD-008. Antiviral Research. PMID 29665374 DOI: 10.1016/J.Antiviral.2018.04.012 |
0.355 |
|
2018 |
Veselenak RL, Milligan GN, Miller AL, Pyles RB, Bourne N. Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2. Virology. 518: 349-357. PMID 29604476 DOI: 10.1016/J.Virol.2018.03.019 |
0.431 |
|
2017 |
Milligan GN, Sarathy VV, White MM, Greenberg MB, Campbell GA, Pyles RB, Barrett ADT, Bourne N. A lethal model of disseminated dengue virus type 1 infection in AG129 mice. The Journal of General Virology. PMID 28949904 DOI: 10.1099/Jgv.0.000923 |
0.379 |
|
2017 |
Medina-Colorado AA, Vincent KL, Miller AL, Maxwell CA, Dawson LN, Olive T, Kozlova EV, Baum MM, Pyles RB. Vaginal ecosystem modeling of growth patterns of anaerobic bacteria in microaerophilic conditions. Anaerobe. PMID 28456518 DOI: 10.1016/J.Anaerobe.2017.04.014 |
0.305 |
|
2016 |
Grimes L, Doyle A, Miller AL, Pyles RB, Olah G, Szabo C, Hoskins S, Eaves-Pyles T. Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury. Plos One. 11: e0166770. PMID 27907005 DOI: 10.1371/Journal.Pone.0166770 |
0.305 |
|
2016 |
Herbst-Kralovetz MM, Pyles RB, Ratner AJ, Sycuro LK, Mitchell C. New Systems for Studying Intercellular Interactions in Bacterial Vaginosis. The Journal of Infectious Diseases. 214: S6-S13. PMID 27449872 DOI: 10.1093/Infdis/Jiw130 |
0.592 |
|
2016 |
Chonmaitree T, Trujillo R, Jennings K, Alvarez-Fernandez P, Patel JA, Loeffelholz MJ, Nokso-Koivisto J, Matalon R, Pyles RB, Miller AL, McCormick DP. Acute Otitis Media and Other Complications of Viral Respiratory Infection. Pediatrics. PMID 27020793 DOI: 10.1542/Peds.2015-3555 |
0.358 |
|
2016 |
Castro Wagner J, Pyles RB, Miller AL, Nokso-Koivisto J, Loeffelholz MJ, Chonmaitree T. Determining Persistence of Bocavirus DNA in the Respiratory Tract of Children by Pyrosequencing. The Pediatric Infectious Disease Journal. PMID 26766144 DOI: 10.1097/Inf.0000000000001058 |
0.323 |
|
2015 |
Nuckols JT, Huang YJ, Higgs S, Miller AL, Pyles RB, Spratt HM, Horne KM, Vanlandingham DL. Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae). Journal of Medical Entomology. 52: 447-51. PMID 26334820 DOI: 10.1093/Jme/Tjv017 |
0.372 |
|
2015 |
Sarathy VV, White M, Li L, Gorder SR, Pyles RB, Campbell GA, Milligan GN, Bourne N, Barrett AD. A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease. Journal of Virology. 89: 1254-66. PMID 25392217 DOI: 10.1128/Jvi.01320-14 |
0.415 |
|
2015 |
Chonmaitree T, Alvarez-Fernandez P, Jennings K, Trujillo R, Marom T, Loeffelholz MJ, Miller AL, McCormick DP, Patel JA, Pyles RB. Symptomatic and asymptomatic respiratory viral infections in the first year of life: association with acute otitis media development. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 1-9. PMID 25205769 DOI: 10.1093/Cid/Ciu714 |
0.379 |
|
2014 |
Nokso-Koivisto J, Pyles RB, Miller AL, Jennings K, Loeffelholz M, Chonmaitree T. Role of Human Bocavirus in Upper Respiratory Tract Infections and Acute Otitis Media. Journal of the Pediatric Infectious Diseases Society. 3: 98-103. PMID 26625362 DOI: 10.1093/Jpids/Pit061 |
0.349 |
|
2014 |
Wali S, Gupta R, Veselenak RL, Li Y, Yu JJ, Murthy AK, Cap AP, Guentzel MN, Chambers JP, Zhong G, Rank RG, Pyles RB, Arulanandam BP. Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs. Plos One. 9: e114261. PMID 25502875 DOI: 10.1371/Journal.Pone.0114261 |
0.304 |
|
2014 |
Pyles RB, Vincent KL, Baum MM, Elsom B, Miller AL, Maxwell C, Eaves-Pyles TD, Li G, Popov VL, Nusbaum RJ, Ferguson MR. Cultivated vaginal microbiomes alter HIV-1 infection and antiretroviral efficacy in colonized epithelial multilayer cultures. Plos One. 9: e93419. PMID 24676219 DOI: 10.1371/Journal.Pone.0093419 |
0.351 |
|
2014 |
Yi M, Hu F, Joyce M, Saxena V, Welsch C, Chavez D, Guerra B, Yamane D, Veselenak R, Pyles R, Walker CM, Tyrrell L, Bourne N, Lanford RE, Lemon SM. Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee. Journal of Virology. 88: 3678-94. PMID 24429362 DOI: 10.1128/Jvi.03540-13 |
0.381 |
|
2014 |
Enderle JL, Miller AL, Pyles RB. Quantification of bacterial uropathogens in preclinical samples using real-time PCR assays. Current Microbiology. 68: 220-6. PMID 24114413 DOI: 10.1007/S00284-013-0465-8 |
0.323 |
|
2013 |
Eaves-Pyles T, Patel J, Arigi E, Cong Y, Cao A, Garg N, Dhiman M, Pyles RB, Arulanandam B, Miller AL, Popov VL, Soong L, Carlsen ED, Coletta C, Szabo C, et al. Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis. Molecular Medicine (Cambridge, Mass.). 19: 263-75. PMID 23922243 DOI: 10.2119/Molmed.2013.00081 |
0.388 |
|
2013 |
Vanlandingham DL, Keil SD, Horne KM, Pyles R, Goodrich RP, Higgs S. Photochemical inactivation of chikungunya virus in plasma and platelets using the Mirasol pathogen reduction technology system. Transfusion. 53: 284-90. PMID 22626525 DOI: 10.1111/J.1537-2995.2012.03717.X |
0.346 |
|
2012 |
Veselenak RL, Shlapobersky M, Pyles RB, Wei Q, Sullivan SM, Bourne N. A Vaxfectin(®)-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes. Vaccine. 30: 7046-51. PMID 23041125 DOI: 10.1016/J.Vaccine.2012.09.057 |
0.381 |
|
2012 |
Rose WA, McGowin CL, Spagnuolo RA, Eaves-Pyles TD, Popov VL, Pyles RB. Commensal bacteria modulate innate immune responses of vaginal epithelial cell multilayer cultures. Plos One. 7: e32728. PMID 22412914 DOI: 10.1371/Journal.Pone.0032728 |
0.372 |
|
2012 |
Nokso-Koivisto J, Pyles RB, Miller AL, Patel JA, Loeffelholz M, Chonmaitree T. Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection. The Pediatric Infectious Disease Journal. 31: 763-6. PMID 22411051 DOI: 10.1097/Inf.0B013E3182539D92 |
0.332 |
|
2011 |
Loeffelholz MJ, Pong DL, Pyles RB, Xiong Y, Miller AL, Bufton KK, Chonmaitree T. Comparison of the filmarray respiratory panel and prodesse real-time PCR assays for detection of respiratory pathogens Journal of Clinical Microbiology. 49: 4083-4088. PMID 21998418 DOI: 10.1128/Jcm.05010-11 |
0.341 |
|
2011 |
Buckner LR, Schust DJ, Ding J, Nagamatsu T, Beatty W, Chang TL, Greene SJ, Lewis ME, Ruiz B, Holman SL, Spagnuolo RA, Pyles RB, Quayle AJ. Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix. Journal of Reproductive Immunology. 92: 8-20. PMID 21943934 DOI: 10.1016/J.Jri.2011.08.002 |
0.355 |
|
2011 |
Pettigrew MM, Gent JF, Pyles RB, Miller AL, Nokso-Koivisto J, Chonmaitree T. Viral-bacterial interactions and risk of acute otitis media complicating upper respiratory tract infection. Journal of Clinical Microbiology. 49: 3750-5. PMID 21900518 DOI: 10.1128/Jcm.01186-11 |
0.35 |
|
2010 |
Pyles RB, Jezek GE, Eaves-Pyles TD. Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection. Infection and Immunity. 78: 1700-10. PMID 20123717 DOI: 10.1128/Iai.00736-09 |
0.343 |
|
2010 |
McGowin CL, Pyles RB. Mucosal treatments for herpes simplex virus: insights on targeted immunoprophylaxis and therapy. Future Microbiology. 5: 15-22. PMID 20020827 DOI: 10.2217/Fmb.09.111 |
0.413 |
|
2010 |
McGowin CL, Spagnuolo RA, Pyles RB. Mycoplasma genitalium rapidly disseminates to the upper reproductive tracts and knees of female mice following vaginal inoculation. Infection and Immunity. 78: 726-36. PMID 19995897 DOI: 10.1128/Iai.00840-09 |
0.361 |
|
2009 |
Rose WA, McGowin CL, Pyles RB. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virology Journal. 6: 195. PMID 19903337 DOI: 10.1186/1743-422X-6-195 |
0.436 |
|
2009 |
McGowin CL, Popov VL, Pyles RB. Intracellular Mycoplasma genitalium infection of human vaginal and cervical epithelial cells elicits distinct patterns of inflammatory cytokine secretion and provides a possible survival niche against macrophage-mediated killing. Bmc Microbiology. 9: 139. PMID 19602269 DOI: 10.1186/1471-2180-9-139 |
0.389 |
|
2009 |
McGowin CL, Ma L, Martin DH, Pyles RB. Mycoplasma genitalium-encoded MG309 activates NF-kappaB via Toll-like receptors 2 and 6 to elicit proinflammatory cytokine secretion from human genital epithelial cells. Infection and Immunity. 77: 1175-81. PMID 19103762 DOI: 10.1128/Iai.00845-08 |
0.373 |
|
2008 |
Rose WA, Tuthill C, Pyles RB. An immunomodulating dipeptide, SCV-07, is a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2). International Journal of Antimicrobial Agents. 32: 262-6. PMID 18619817 DOI: 10.1016/J.Ijantimicag.2008.04.010 |
0.37 |
|
2008 |
Herbst-Kralovetz MM, Quayle AJ, Ficarra M, Greene S, Rose WA, Chesson R, Spagnuolo RA, Pyles RB. Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 59: 212-24. PMID 18201283 DOI: 10.1111/J.1600-0897.2007.00566.X |
0.623 |
|
2007 |
Gentry M, Taormina J, Pyles RB, Yeager L, Kirtley M, Popov VL, Klimpel G, Eaves-Pyles T. Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection. Infection and Immunity. 75: 3969-78. PMID 17502386 DOI: 10.1128/Iai.00157-07 |
0.327 |
|
2007 |
Kawana K, Quayle AJ, Ficarra M, Ibana JA, Shen L, Kawana Y, Yang H, Marrero L, Yavagal S, Greene SJ, Zhang YX, Pyles RB, Blumberg RS, Schust DJ. CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity. The Journal of Biological Chemistry. 282: 7368-75. PMID 17215251 DOI: 10.1074/Jbc.M610754200 |
0.366 |
|
2006 |
Herbst-Kralovetz MM, Pyles RB. Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection. Journal of Virology. 80: 9988-97. PMID 17005677 DOI: 10.1128/Jvi.01099-06 |
0.658 |
|
2006 |
Herbst-Kralovetz MM, Pyles RB. Toll-like receptors, innate immunity and HSV pathogenesis Herpes. 13: 37-41. PMID 16895653 |
0.634 |
|
2005 |
Bourne N, Milligan GN, Stanberry LR, Stegall R, Pyles RB. Impact of immunization with glycoprotein D2/AS04 on herpes simplex virus type 2 shedding into the genital tract in guinea pigs that become infected. The Journal of Infectious Diseases. 192: 2117-23. PMID 16288376 DOI: 10.1086/498247 |
0.431 |
|
2003 |
Herbst MM, Pyles RB. Immunostimulatory CpG treatment for genital HSV-2 infections. The Journal of Antimicrobial Chemotherapy. 52: 887-9. PMID 14585849 DOI: 10.1093/Jac/Dkg481 |
0.332 |
|
2002 |
Pyles RB, Higgins D, Chalk C, Zalar A, Eiden J, Brown C, Van Nest G, Stanberry LR. Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection. Journal of Virology. 76: 11387-96. PMID 12388699 DOI: 10.1128/Jvi.76.22.11387-11396.2002 |
0.418 |
|
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