| Year |
Citation |
Score |
| 2024 |
Yuki K, Vallon M, Ding J, Rada CC, Tang AT, Vilches-Moure JG, McCormick AK, Echeverri MFH, Alwahabi S, Braunger BM, Ergün S, Kahn ML, Kuo CJ. GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism. Development (Cambridge, England). PMID 38682276 DOI: 10.1242/dev.202794 |
0.345 |
|
| 2023 |
Jannaway M, Iyer D, Mastrogiacomo DM, Li K, Sung DC, Yang Y, Kahn ML, Scallan JP. VEGFR3 is required for button junction formation in lymphatic vessels. Cell Reports. 42: 112777. PMID 37454290 DOI: 10.1016/j.celrep.2023.112777 |
0.341 |
|
| 2022 |
Sung DC, Chen X, Chen M, Yang J, Schultz S, Babu A, Xu Y, Gao S, Stevenson Keller TC, Mericko P, Lee M, Yang Y, Scallan JP, Kahn ML. VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development. Elife. 11. PMID 35486098 DOI: 10.7554/eLife.77241 |
0.321 |
|
| 2022 |
Yang Y, Mumau M, Tober J, Zhu Q, Bennett L, Hong C, Sung DC, Keller TCS, Uzun Y, Gao P, Shewale S, Chen M, Yang J, Chen X, Thomas SA, ... ... Kahn ML, et al. Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis. Blood. PMID 35245372 DOI: 10.1182/blood.2021013934 |
0.325 |
|
| 2021 |
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, ... ... Kahn ML, et al. PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism. Nature. PMID 33910229 DOI: 10.1038/s41586-021-03562-8 |
0.312 |
|
| 2020 |
Hong CC, Tang AT, Detter MR, Choi JP, Wang R, Yang X, Guerrero AA, Wittig CF, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Goddard LM, ... ... Kahn ML, et al. Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican. The Journal of Experimental Medicine. 217. PMID 32648916 DOI: 10.1084/Jem.20200140 |
0.412 |
|
| 2020 |
Betterman KL, Sutton DL, Secker GA, Kazenwadel J, Oszmiana A, Lim L, Miura N, Sorokin L, Hogan BM, Kahn ML, McNeill H, Harvey NL. Atypical cadherin Fat4 orchestrates lymphatic endothelial cell polarity in response to flow. The Journal of Clinical Investigation. PMID 32182215 DOI: 10.1172/Jci99027 |
0.387 |
|
| 2019 |
Tang AT, Sullivan KR, Hong CC, Goddard LM, Mahadevan A, Ren A, Pardo H, Peiper A, Griffin E, Tanes C, Mattei LM, Yang J, Li L, Mericko-Ishizuka P, Shen L, ... ... Kahn ML, et al. Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Science Translational Medicine. 11. PMID 31776290 DOI: 10.1126/Scitranslmed.Aaw3521 |
0.368 |
|
| 2019 |
Welsh JD, Hoofnagle MH, Bamezai S, Oxendine M, Lim L, Hall JD, Yang J, Schultz S, Engel JD, Kume T, Oliver G, Jimenez JM, Kahn ML. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. The Journal of Clinical Investigation. PMID 31710307 DOI: 10.1172/Jci124791 |
0.432 |
|
| 2019 |
Lim L, Bui H, Farrelly O, Yang J, Li L, Enis D, Ma W, Chen M, Oliver G, Welsh J, Kahn ML. Hemostasis stimulates lymphangiogenesis through release and activation of VEGFC. Blood. PMID 31562136 DOI: 10.1182/Blood.2019001736 |
0.34 |
|
| 2019 |
Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, ... ... Kahn ML, et al. Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations. Acta Neuropathologica Communications. 7: 132. PMID 31426861 DOI: 10.1186/S40478-019-0789-0 |
0.325 |
|
| 2019 |
Pawlak JB, Bálint L, Lim L, Ma W, Davis RB, Benyo Z, Soares MJ, Oliver G, Kahn ML, Jakus Z, Caron KM. Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling. The Journal of Clinical Investigation. PMID 31415243 DOI: 10.1172/Jci120446 |
0.417 |
|
| 2019 |
Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, ... ... Kahn ML, et al. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes. Jci Insight. 4. PMID 30728328 DOI: 10.1172/Jci.Insight.126167 |
0.306 |
|
| 2019 |
Koskimäki J, Girard R, Li Y, Zeineddine H, Lightle R, Moore T, Lyne S, Shenkar R, Saadat L, Cao Y, Polster SP, Zhang D, Carrion-Penagos J, Lopez-Ramirez MA, Chapman E, ... ... Kahn ML, et al. Abstract 64: Novel and Known Genes Elucidated in Cerebral Cavernous Malformation Through Comparative Transcriptomic Analysis of Multiple Model Species and Human Microdissected Lesional Endothelial Cells Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.64 |
0.327 |
|
| 2018 |
Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A. Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proceedings of the National Academy of Sciences of the United States of America. 115: 12817-12822. PMID 30482854 DOI: 10.1073/Pnas.1817070115 |
0.374 |
|
| 2018 |
Sweet DT, Hall JD, Welsh J, Kahn ML, Jiménez JM. Investigating Effects of Fluid Shear Stress on Lymphatic Endothelial Cells. Methods in Molecular Biology (Clifton, N.J.). 1846: 213-227. PMID 30242762 DOI: 10.1007/978-1-4939-8712-2_14 |
0.392 |
|
| 2018 |
Gollomp K, Kim M, Johnston I, Hayes V, Welsh J, Arepally GM, Kahn M, Lambert MP, Cuker A, Cines DB, Rauova L, Kowalska MA, Poncz M. Neutrophil accumulation and NET release contribute to thrombosis in HIT. Jci Insight. 3. PMID 30232279 DOI: 10.1172/Jci.Insight.99445 |
0.41 |
|
| 2018 |
Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, ... ... Kahn ML, et al. Phenotypic characterization of murine models of cerebral cavernous malformations. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29946133 DOI: 10.1038/S41374-018-0030-Y |
0.312 |
|
| 2017 |
Goddard LM, Duchemin AL, Ramalingan H, Wu B, Chen M, Bamezai S, Yang J, Li L, Morley MP, Wang T, Scherrer-Crosbie M, Frank DB, Engleka KA, Jameson SC, Morrisey EE, ... ... Kahn ML, et al. Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis. Developmental Cell. PMID 29056552 DOI: 10.1016/J.Devcel.2017.09.023 |
0.374 |
|
| 2017 |
Goddard LM, Kahn ML. A BMPy Road for Venous Development. Developmental Cell. 42: 435-436. PMID 28898672 DOI: 10.1016/J.Devcel.2017.08.016 |
0.361 |
|
| 2017 |
Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, ... ... Kahn ML, et al. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. PMID 28489816 DOI: 10.1038/Nature22075 |
0.415 |
|
| 2016 |
Welsh JD, Kahn ML, Sweet DT. Lymphovenous hemostasis and the role of platelets in regulating lymphatic flow and lymphatic vessel maturation. Blood. PMID 27385789 DOI: 10.1182/Blood-2016-04-636415 |
0.513 |
|
| 2016 |
Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS. Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes & Development. PMID 27313318 DOI: 10.1101/Gad.282400.116 |
0.393 |
|
| 2016 |
Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, ... Kahn ML, et al. Corrigendum: Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. PMID 27281211 DOI: 10.1038/Nature18311 |
0.433 |
|
| 2016 |
Bui HM, Enis D, Robciuc MR, Nurmi HJ, Cohen J, Chen M, Yang Y, Dhillon V, Johnson K, Zhang H, Kirkpatrick R, Traxler E, Anisimov A, Alitalo K, Kahn ML. Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD. The Journal of Clinical Investigation. PMID 27159393 DOI: 10.1172/Jci83967 |
0.355 |
|
| 2016 |
Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, ... Kahn ML, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. PMID 27027284 DOI: 10.1038/Nature17178 |
0.452 |
|
| 2015 |
Sweet DT, Jiménez JM, Chang J, Hess PR, Mericko-Ishizuka P, Fu J, Xia L, Davies PF, Kahn ML. Lymph flow regulates collecting lymphatic vessel maturation in vivo. The Journal of Clinical Investigation. 125: 2995-3007. PMID 26214523 DOI: 10.1172/Jci79386 |
0.442 |
|
| 2015 |
Kahn ML. Vascular development for climate control. Developmental Cell. 33: 241-2. PMID 25942619 DOI: 10.1016/J.Devcel.2015.04.011 |
0.376 |
|
| 2015 |
Manne BK, Badolia R, Dangelmaier C, Eble JA, Ellmeier W, Kahn M, Kunapuli SP. Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets. The Journal of Biological Chemistry. 290: 11557-68. PMID 25767114 DOI: 10.1074/Jbc.M114.629527 |
0.421 |
|
| 2015 |
Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML. Cell Adhesion Mediated by VCAM-ITGα9 Interactions Enables Lymphatic Development. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1179-89. PMID 25745057 DOI: 10.1161/Atvbaha.114.304997 |
0.429 |
|
| 2015 |
Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Developmental Cell. 32: 168-80. PMID 25625206 DOI: 10.1016/J.Devcel.2014.12.009 |
0.448 |
|
| 2014 |
Boulaftali Y, Hess PR, Kahn ML, Bergmeier W. Platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling and vascular integrity. Circulation Research. 114: 1174-84. PMID 24677237 DOI: 10.1161/Circresaha.114.301611 |
0.467 |
|
| 2014 |
Zheng X, Riant F, Bergametti F, Myers CD, Tang AT, Kleaveland B, Pan W, Yang J, Tournier-Lasserve E, Kahn ML. Cerebral cavernous malformations arise independent of the heart of glass receptor. Stroke; a Journal of Cerebral Circulation. 45: 1505-9. PMID 24643410 DOI: 10.1161/Strokeaha.114.004809 |
0.775 |
|
| 2014 |
Hess PR, Rawnsley DR, Jakus Z, Yang Y, Sweet DT, Fu J, Herzog B, Lu M, Nieswandt B, Oliver G, Makinen T, Xia L, Kahn ML. Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. The Journal of Clinical Investigation. 124: 273-84. PMID 24292710 DOI: 10.1172/Jci70422 |
0.458 |
|
| 2013 |
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, ... ... Kahn ML, et al. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature. 502: 105-9. PMID 23995678 DOI: 10.1038/Nature12501 |
0.421 |
|
| 2013 |
Stanger BZ, Kahn ML. Platelets and tumor cells: a new form of border control. Cancer Cell. 24: 9-11. PMID 23845439 DOI: 10.1016/J.Ccr.2013.06.009 |
0.309 |
|
| 2013 |
Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML. The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. The Journal of Biological Chemistry. 288: 24429-40. PMID 23836893 DOI: 10.1074/Jbc.M113.463083 |
0.328 |
|
| 2013 |
Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML. The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 121: 3228-36. PMID 23426945 DOI: 10.1182/Blood-2012-10-462689 |
0.338 |
|
| 2013 |
Boulaftali Y, Hess PR, Getz TM, Cholka A, Stolla M, Mackman N, Owens AP, Ware J, Kahn ML, Bergmeier W. Platelet ITAM signaling is critical for vascular integrity in inflammation. The Journal of Clinical Investigation. 123: 908-16. PMID 23348738 DOI: 10.1172/Jci65154 |
0.499 |
|
| 2013 |
Liang X, Russell SR, Estelle S, Jones LH, Cho S, Kahn ML, Berndt MC, Bunting ST, Ware J, Li R. Specific Inhibition Of Ectodomain Shedding Of GPIba By Targeting Its Shedding Cleavage Site Blood. 122: 21-21. DOI: 10.1182/Blood.V122.21.21.21 |
0.382 |
|
| 2012 |
Zheng X, Xu C, Smith AO, Stratman AN, Zou Z, Kleaveland B, Yuan L, Didiku C, Sen A, Liu X, Skuli N, Zaslavsky A, Chen M, Cheng L, Davis GE, ... Kahn ML, et al. Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth. Developmental Cell. 23: 342-55. PMID 22898778 DOI: 10.1016/J.Devcel.2012.06.004 |
0.776 |
|
| 2012 |
Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, ... ... Kahn ML, et al. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity. 37: 276-89. PMID 22884313 DOI: 10.1016/J.Immuni.2012.05.022 |
0.371 |
|
| 2012 |
Chen CY, Bertozzi C, Zou Z, Yuan L, Lee JS, Lu M, Stachelek SJ, Srinivasan S, Guo L, Vicente A, Vincente A, Mericko P, Levy RJ, Makinen T, Oliver G, ... Kahn ML, et al. Blood flow reprograms lymphatic vessels to blood vessels. The Journal of Clinical Investigation. 122: 2006-17. PMID 22622036 DOI: 10.1172/Jci57513 |
0.715 |
|
| 2012 |
Chen CY, Bertozzi C, Zou Z, Yuan L, Lee JS, Lu M, Stachelek SJ, Srinivasan S, Guo L, Vicente A, Mericko P, Levy RJ, Makinen T, Oliver G, Kahn ML. Blood flow reprograms lymphatic vessels to blood vessels (Journal of Clinical Investigation (2012) 122, 6 (2006-2017) DOI: 10.1172/JCI57513) Journal of Clinical Investigation. 122: 2702. DOI: 10.1172/Jci65314 |
0.58 |
|
| 2011 |
Schmaier AA, Stalker TJ, Runge JJ, Lee D, Nagaswami C, Mericko P, Chen M, Cliché S, Gariépy C, Brass LF, Hammer DA, Weisel JW, Rosenthal K, Kahn ML. Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease. Blood. 118: 3661-9. PMID 21816834 DOI: 10.1182/Blood-2011-02-338244 |
0.728 |
|
| 2010 |
Bertozzi CC, Hess PR, Kahn ML. Platelets: covert regulators of lymphatic development. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2368-71. PMID 21071706 DOI: 10.1161/Atvbaha.110.217281 |
0.666 |
|
| 2010 |
Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML. CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations. The Journal of Clinical Investigation. 120: 2795-804. PMID 20592472 DOI: 10.1172/Jci39679 |
0.784 |
|
| 2010 |
Bertozzi CC, Schmaier AA, Mericko P, Hess PR, Zou Z, Chen M, Chen CY, Xu B, Lu MM, Zhou D, Sebzda E, Santore MT, Merianos DJ, Stadtfeld M, Flake AW, ... ... Kahn ML, et al. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood. 116: 661-70. PMID 20363774 DOI: 10.1182/Blood-2010-02-270876 |
0.81 |
|
| 2010 |
Kahn ML. Jazzing up vessel growth. Blood. 115: 1479. PMID 20185593 DOI: 10.1182/Blood-2009-11-254995 |
0.469 |
|
| 2009 |
Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the United States of America. 106: 21167-72. PMID 19940238 DOI: 10.1073/Pnas.0906436106 |
0.739 |
|
| 2009 |
Schmaier AA, Kahn ML. Platelet integrin signaling: wherefore art thou? Blood. 114: 2571-2. PMID 19779046 DOI: 10.1182/Blood-2009-08-235283 |
0.733 |
|
| 2009 |
Zou Z, Schmaier AA, Cheng L, Mericko P, Dickeson SK, Stricker TP, Santoro SA, Kahn ML. Negative regulation of activated alpha-2 integrins during thrombopoiesis. Blood. 113: 6428-39. PMID 19258597 DOI: 10.1182/Blood-2008-08-175356 |
0.727 |
|
| 2009 |
Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nature Medicine. 15: 169-76. PMID 19151727 DOI: 10.1038/Nm.1918 |
0.791 |
|
| 2009 |
Miller MW, Basra S, Kulp DW, Billings PC, Choi S, Beavers MP, McCarty OJ, Zou Z, Kahn ML, Bennett JS, DeGrado WF. Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism. Proceedings of the National Academy of Sciences of the United States of America. 106: 719-24. PMID 19141632 DOI: 10.1073/Pnas.0811622106 |
0.368 |
|
| 2009 |
Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu M, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. Erratum: Corrigendum: Regulation of cardiovascular development and integrity by the heart of glass– cerebral cavernous malformation protein pathway Nature Medicine. 15: 584-584. DOI: 10.1038/Nm0509-584A |
0.747 |
|
| 2008 |
Neeves KB, Maloney SF, Fong KP, Schmaier AA, Kahn ML, Brass LF, Diamond SL. Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates. Journal of Thrombosis and Haemostasis : Jth. 6: 2193-201. PMID 18983510 DOI: 10.1111/J.1538-7836.2008.03188.X |
0.732 |
|
| 2008 |
Bezman NA, Lian L, Abrams CS, Brass LF, Kahn ML, Jordan MS, Koretzky GA. Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo. The Journal of Experimental Medicine. 205: 1775-88. PMID 18663126 DOI: 10.1084/Jem.20080240 |
0.432 |
|
| 2008 |
Sebzda E, Zou Z, Lee JS, Wang T, Kahn ML. Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns. Nature Immunology. 9: 292-300. PMID 18246069 DOI: 10.1038/Ni1565 |
0.322 |
|
| 2008 |
Kahn ML. Blood is thicker than lymph. The Journal of Clinical Investigation. 118: 23-6. PMID 18097477 DOI: 10.1172/Jci34485 |
0.423 |
|
| 2008 |
Gardiner EE, Karunakaran D, Arthur JF, Mu FT, Powell MS, Baker RI, Hogarth PM, Kahn ML, Andrews RK, Berndt MC. Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa. Blood. 111: 165-74. PMID 17848620 DOI: 10.1182/Blood-2007-04-086983 |
0.449 |
|
| 2008 |
Bur AM, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kahn ML, Brass LF. Microfluidic Flow Studies of Murine Thrombus Formation and Stability on Collagen. Blood. 112: 1835-1835. DOI: 10.1182/Blood.V112.11.1835.1835 |
0.3 |
|
| 2007 |
Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE. Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. The Journal of Biological Chemistry. 282: 30434-41. PMID 17690106 DOI: 10.1074/Jbc.M701330200 |
0.436 |
|
| 2007 |
Kasirer-Friede A, Kahn ML, Shattil SJ. Platelet integrins and immunoreceptors. Immunological Reviews. 218: 247-64. PMID 17624957 DOI: 10.1111/J.1600-065X.2007.00532.X |
0.454 |
|
| 2007 |
Zou Z, Chen H, Schmaier AA, Hynes RO, Kahn ML. Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets. Blood. 109: 3284-90. PMID 17170121 DOI: 10.1182/Blood-2006-10-051664 |
0.736 |
|
| 2007 |
Arthur J, Gardiner E, Shen Y, Kahn M, Berndt M, Andrews R. RAPID LIGAND-INDUCED DIMERIZATION OF PLATELET GLYCOPROTEIN VI Journal of Thrombosis and Haemostasis. 5: O-M-028-O-M-028. DOI: 10.1111/J.1538-7836.2007.Tb00855.X |
0.338 |
|
| 2006 |
Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML. Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Developmental Cell. 11: 845-57. PMID 17141159 DOI: 10.1016/J.Devcel.2006.09.006 |
0.625 |
|
| 2006 |
Kahn ML, Koretzky GA. Integrins and ITAMs: more than just good neighbors. Nature Immunology. 7: 1286-8. PMID 17110948 DOI: 10.1038/Ni1206-1286 |
0.307 |
|
| 2006 |
Samaha FF, Kahn ML. Novel platelet and vascular roles for immunoreceptor signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2588-93. PMID 17023681 DOI: 10.1161/01.Atv.0000248734.89782.37 |
0.519 |
|
| 2006 |
Sebzda E, Hibbard C, Sweeney S, Abtahian F, Bezman N, Clemens G, Maltzman JS, Cheng L, Liu F, Turner M, Tybulewicz V, Koretzky GA, Kahn ML. Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Developmental Cell. 11: 349-61. PMID 16950126 DOI: 10.1016/J.Devcel.2006.07.007 |
0.439 |
|
| 2006 |
Abtahian F, Bezman N, Clemens R, Sebzda E, Cheng L, Shattil SJ, Kahn ML, Koretzky GA. Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. Molecular and Cellular Biology. 26: 6936-49. PMID 16943434 DOI: 10.1128/Mcb.01040-06 |
0.371 |
|
| 2006 |
Horii K, Kahn ML, Herr AB. Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI. Blood. 108: 936-42. PMID 16861347 DOI: 10.1182/Blood-2006-01-010215 |
0.419 |
|
| 2006 |
Chen H, Zou Z, Sarratt KL, Zhou D, Zhang M, Sebzda E, Hammer DA, Kahn ML. In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines. Genes & Development. 20: 927-32. PMID 16618804 DOI: 10.1101/Gad.1408306 |
0.319 |
|
| 2006 |
Boylan B, Berndt MC, Kahn ML, Newman PJ. Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents. Blood. 108: 908-14. PMID 16569773 DOI: 10.1182/Blood-2005-07-2937 |
0.4 |
|
| 2006 |
Kahn ML. GPVI: No magic bullet for thrombosis Blood. 107: 4199. DOI: 10.1182/Blood-2006-03-008342 |
0.414 |
|
| 2005 |
Sarratt KL, Chen H, Zutter MM, Santoro SA, Hammer DA, Kahn ML. GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Blood. 106: 1268-77. PMID 15886326 DOI: 10.1182/Blood-2004-11-4434 |
0.451 |
|
| 2005 |
Arthur JF, Gardiner EE, Matzaris M, Taylor SG, Wijeyewickrema L, Ozaki Y, Kahn ML, Andrews RK, Berndt MC. Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets. Thrombosis and Haemostasis. 93: 716-23. PMID 15841318 DOI: 10.1160/Th04-09-0584 |
0.377 |
|
| 2004 |
Samaha FF, Hibbard C, Sacks J, Chen H, Varello MA, George T, Kahn ML. Measurement of platelet collagen receptor density in human subjects. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: e181-2. PMID 15528484 DOI: 10.1161/01.Atv.0000144809.49724.71 |
0.439 |
|
| 2004 |
Xu B, deWaal RM, Mor-Vaknin N, Hibbard C, Markovitz DM, Kahn ML. The endothelial cell-specific antibody PAL-E identifies a secreted form of vimentin in the blood vasculature. Molecular and Cellular Biology. 24: 9198-206. PMID 15456890 DOI: 10.1128/Mcb.24.20.9198-9206.2004 |
0.406 |
|
| 2004 |
Kahn ML. Platelet-collagen responses: molecular basis and therapeutic promise. Seminars in Thrombosis and Hemostasis. 30: 419-25. PMID 15354263 DOI: 10.1055/S-2004-833477 |
0.442 |
|
| 2004 |
Gardiner EE, Arthur JF, Kahn ML, Berndt MC, Andrews RK. Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase. Blood. 104: 3611-7. PMID 15308568 DOI: 10.1182/Blood-2004-04-1549 |
0.419 |
|
| 2004 |
Sarratt KL, Chen H, Kahn ML, Hammer DA. Platelet receptor glycoprotein VI-mediated adhesion to type I collagen under hydrodynamic flow. Annals of Biomedical Engineering. 32: 970-6. PMID 15298434 DOI: 10.1023/B:Abme.0000032459.29696.65 |
0.415 |
|
| 2004 |
Boylan B, Chen H, Rathore V, Paddock C, Salacz M, Friedman KD, Curtis BR, Stapleton M, Newman DK, Kahn ML, Newman PJ. Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. Blood. 104: 1350-5. PMID 15150079 DOI: 10.1182/Blood-2004-03-0896 |
0.4 |
|
| 2004 |
Berndt MC, Arthur JF, Gardiner EE, Ozaki Y, Kahn ML, Andrews RK. Glycoprotein (GP) VI Is Associated with GPIb-IX-V on the Membrane of Resting and Activated Platelets. Blood. 104: 1553-1553. DOI: 10.1182/Blood.V104.11.1553.1553 |
0.381 |
|
| 2004 |
Kahn ML. Platelet collagen receptors play molecular ping-pong Blood. 103: 1180-1181. DOI: 10.1182/Blood-2003-11-4080 |
0.442 |
|
| 2004 |
Sebzda E, Hibbard C, Abtahian F, Tybulewicz V, Koretzky GA, Kahn ML. BLOOD-LYMPHATIC VESSEL INTEGRITY REQUIRES SYK TYROSINE KINASE SIGNALING WITHIN THE ENDOTHELIAL CELL COMPARTMENT Cardiovascular Pathology. 13: 21. DOI: 10.1016/J.Carpath.2004.03.056 |
0.321 |
|
| 2003 |
Chen H, Kahn ML. Reciprocal signaling by integrin and nonintegrin receptors during collagen activation of platelets. Molecular and Cellular Biology. 23: 4764-77. PMID 12832464 DOI: 10.1128/Mcb.23.14.4764-4777.2003 |
0.479 |
|
| 2003 |
Locke D, Liu C, Peng X, Chen H, Kahn ML. Fc Rgamma -independent signaling by the platelet collagen receptor glycoprotein VI. The Journal of Biological Chemistry. 278: 15441-8. PMID 12594225 DOI: 10.1074/Jbc.M212338200 |
0.412 |
|
| 2003 |
Abtahian F, Guerriero A, Sebzda E, Lu MM, Zhou R, Mocsai A, Myers EE, Huang B, Jackson DG, Ferrari VA, Tybulewicz V, Lowell CA, Lepore JJ, Koretzky GA, Kahn ML. Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science (New York, N.Y.). 299: 247-51. PMID 12522250 DOI: 10.1126/Science.1079477 |
0.484 |
|
| 2003 |
Larson MK, Chen H, Kahn ML, Taylor AM, Fabre JE, Mortensen RM, Conley PB, Parise LV. Identification of P2Y12-dependent and -independent mechanisms of glycoprotein VI-mediated Rap1 activation in platelets. Blood. 101: 1409-15. PMID 12393417 DOI: 10.1182/Blood-2002-05-1533 |
0.457 |
|
| 2003 |
Samaha FF, Varello M, Kahn ML. Platelet collagen receptor glycoprotein VI as a novel risk factor for myocardial infarction Journal of the American College of Cardiology. 41: 404. DOI: 10.1016/S0735-1097(03)81176-2 |
0.344 |
|
| 2002 |
Camerer E, Kataoka H, Kahn M, Lease K, Coughlin SR. Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. The Journal of Biological Chemistry. 277: 16081-7. PMID 11850418 DOI: 10.1074/Jbc.M108555200 |
0.461 |
|
| 2002 |
Locke D, Chen H, Liu Y, Liu C, Kahn ML. Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI. The Journal of Biological Chemistry. 277: 18801-9. PMID 11844795 DOI: 10.1074/Jbc.M111520200 |
0.397 |
|
| 2002 |
Chen H, Locke D, Liu Y, Liu C, Kahn ML. The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion. The Journal of Biological Chemistry. 277: 3011-9. PMID 11723134 DOI: 10.1074/Jbc.M109714200 |
0.456 |
|
| 2001 |
Tulasne D, Judd BA, Johansen M, Asazuma N, Best D, Brown EJ, Kahn M, Koretzky GA, Watson SP. C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination. Blood. 98: 3346-52. PMID 11719373 DOI: 10.1182/Blood.V98.12.3346 |
0.406 |
|
| 2001 |
Moog S, Mangin P, Lenain N, Strassel C, Ravanat C, Schuhler S, Freund M, Santer M, Kahn M, Nieswandt B, Gachet C, Cazenave JP, Lanza F. Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation. Blood. 98: 1038-46. PMID 11493449 DOI: 10.1182/Blood.V98.4.1038 |
0.41 |
|
| 2001 |
O'Brien PJ, Molino M, Kahn M, Brass LF. Protease activated receptors: Theme and variations Oncogene. 20: 1570-1581. PMID 11313904 DOI: 10.1038/Sj.Onc.1204194 |
0.319 |
|
| 2001 |
Zheng YM, Liu C, Chen H, Locke D, Ryan JC, Kahn ML. Expression of the platelet receptor GPVI confers signaling via the Fc receptor gamma -chain in response to the snake venom convulxin but not to collagen. The Journal of Biological Chemistry. 276: 12999-3006. PMID 11152687 DOI: 10.1074/Jbc.M009344200 |
0.47 |
|
| 2000 |
Lindner JR, Kahn ML, Coughlin SR, Sambrano GR, Schauble E, Bernstein D, Foy D, Hafezi-Moghadam A, Ley K. Delayed onset of inflammation in protease-activated receptor-2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 6504-10. PMID 11086091 DOI: 10.4049/Jimmunol.165.11.6504 |
0.335 |
|
| 1999 |
Kahn ML, Diacovo TG, Bainton DF, Lanza F, Trejo J, Coughlin SR. Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype. Blood. 94: 4112-21. PMID 10590056 DOI: 10.1182/Blood.V94.12.4112 |
0.431 |
|
| 1999 |
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. The Journal of Clinical Investigation. 103: 879-87. PMID 10079109 DOI: 10.1172/Jci6042 |
0.417 |
|
| 1998 |
Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng D, Moff S, Farese RV, Tam C, Coughlin SR. A dual thrombin receptor system for platelet activation. Nature. 394: 690-4. PMID 9716134 DOI: 10.1038/29325 |
0.443 |
|
| 1997 |
Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature. 386: 502-6. PMID 9087410 DOI: 10.1038/386502A0 |
0.433 |
|
| 1996 |
Connolly AJ, Ishihara H, Kahn ML, Farese RV, Coughlin SR. Role of the thrombin receptor in development and evidence for a second receptor. Nature. 381: 516-9. PMID 8632823 DOI: 10.1038/381516A0 |
0.463 |
|
| 1996 |
Kahn M, Ishii K, Kuo W, Piper M, Connolly A, Shi Y, Wu R, Lin CC, Coughlin SR. Conserved Structure and Adjacent Location of the Thrombin Receptor and Protease-Activated Receptor 2 Genes Define a Protease-Activated Receptor Gene Cluster Molecular Medicine. 2: 349-357. DOI: 10.1007/Bf03401632 |
0.335 |
|
| 1993 |
Lee SW, Kahn ML, Dichek DA. Control of clot lysis by gene transfer Trends in Cardiovascular Medicine. 3: 61-66. DOI: 10.1016/1050-1738(93)90038-8 |
0.352 |
|
| 1992 |
Kahn ML, Lee SW, Dichek DA. Optimization of retroviral vector-mediated gene transfer into endothelial cells in vitro Circulation Research. 71: 1508-1517. PMID 1423943 DOI: 10.1161/01.Res.71.6.1508 |
0.323 |
|
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