| Year |
Citation |
Score |
| 2024 |
Khan N, Hu Y, Lowell CA, Rothstein TL. TLR Engagement Induces an Alternate Pathway for BCR Signaling that Results in PKCδ Phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). PMID 38629913 DOI: 10.4049/jimmunol.2300784 |
0.304 |
|
| 2022 |
Brian BF, Sauer ML, Greene JT, Senevirathne SE, Lindstedt AJ, Funk OL, Ruis BL, Ramirez LA, Auger JL, Swanson WL, Nunez MG, Moriarity BS, Lowell CA, Binstadt BA, Freedman TS. A dominant function of LynB kinase in preventing autoimmunity. Science Advances. 8: eabj5227. PMID 35452291 DOI: 10.1126/sciadv.abj5227 |
0.317 |
|
| 2021 |
Margraf A, Lowell CA, Zarbock A. Neutrophils in acute inflammation - current concepts and translational implications. Blood. PMID 34624098 DOI: 10.1182/blood.2021012295 |
0.301 |
|
| 2020 |
Grimes D, Johnson R, Pashos M, Cummings C, Kang C, Sampedro GR, Tycksen E, McBride HJ, Sah R, Lowell CA, Clemens RA. ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929002 DOI: 10.1073/Pnas.2008032117 |
0.35 |
|
| 2020 |
Cleary SJ, Kwaan N, Tian JJ, Calabrese DR, Mallavia B, Magnen M, Greenland JR, Urisman A, Singer JP, Hays SR, Kukreja J, Hay AM, Howie HL, Toy P, Lowell CA, et al. Complement activation on endothelium initiates antibody-mediated acute lung injury. The Journal of Clinical Investigation. PMID 32730229 DOI: 10.1172/Jci138136 |
0.342 |
|
| 2020 |
Liang J, Zhang JJ, Huang HI, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, Hammer GE. The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection. Infection and Immunity. PMID 32540868 DOI: 10.1128/Iai.00048-20 |
0.349 |
|
| 2020 |
Poh AR, Dwyer AR, Eissmann MF, Chand AL, Baloyan D, Boon L, Murrey MW, Whitehead L, O'Brien M, Lowell CA, Putoczki TL, Pixley FJ, O'Donoghue RJ, Ernst M. Inhibition of the SRC kinase HCK impairs STAT3-dependent gastric tumor growth in mice. Cancer Immunology Research. PMID 31992566 DOI: 10.1158/2326-6066.Cir-19-0623 |
0.402 |
|
| 2019 |
Rohwedder I, Kurz ARM, Pruenster M, Immler R, Pick R, Eggersmann T, Klapproth S, Johnson JL, Masgrau Alsina S, Lowell CA, Mócsai A, Catz SD, Sperandio M. Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration. Haematologica. PMID 31699792 DOI: 10.3324/Haematol.2019.225722 |
0.496 |
|
| 2019 |
Ma J, Abram CL, Hu Y, Lowell CA. CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases. Science Signaling. 12. PMID 31594855 DOI: 10.1126/Scisignal.Aao3829 |
0.443 |
|
| 2019 |
Cappenberg A, Margraf A, Thomas K, Bardel B, McCreedy DA, Van Marck V, Mellmann A, Lowell CA, Zarbock A. L-selectin shedding affects bacterial clearance in the lung - a new regulatory pathway for integrin-outside-in signaling. Blood. PMID 31366620 DOI: 10.1182/Blood.2019000685 |
0.379 |
|
| 2019 |
Clemens RA, Lowell CA. CRAC channel regulation of innate immune cells in health and disease. Cell Calcium. 78: 56-65. PMID 30641250 DOI: 10.1016/J.Ceca.2019.01.003 |
0.364 |
|
| 2017 |
Herter JM, Margraf A, Volmering S, Correia BE, Bradshaw JM, Bisconte A, Hill RJ, Langrish CL, Lowell CA, Zarbock A. The Bruton's tyrosine kinase inhibitor PRN473 inhibits neutrophil recruitment via inhibition of Mac-1 signaling. British Journal of Pharmacology. PMID 29130484 DOI: 10.1111/Bph.14090 |
0.429 |
|
| 2017 |
Zikherman J, Lowell CA. B cell autoimmunity at the extremes. Nature Immunology. 18: 1065-1066. PMID 28926534 DOI: 10.1038/Ni.3840 |
0.355 |
|
| 2017 |
Clemens RA, Chong J, Grimes D, Hu Y, Lowell CA. STIM1 and STIM2 cooperatively regulate mouse neutrophil store operated calcium entry and cytokine production. Blood. PMID 28724541 DOI: 10.1182/Blood-2016-11-751230 |
0.369 |
|
| 2017 |
Costa S, Marini O, Bevilacqua D, DeFranco AL, Hou B, Lonardi S, Vermi W, Rodegher P, Panato A, Tagliaro F, Lowell CA, Cassatella MA, Girolomoni G, Scapini P. Role of MyD88 signaling in the imiquimod-induced mouse model of psoriasis: focus on innate myeloid cells. Journal of Leukocyte Biology. PMID 28642279 DOI: 10.1189/Jlb.3Ma0217-054Rr |
0.423 |
|
| 2017 |
Abram CL, Lowell CA. Shp1 function in myeloid cells. Journal of Leukocyte Biology. PMID 28606940 DOI: 10.1189/Jlb.2Mr0317-105R |
0.415 |
|
| 2017 |
Chen J, Zhong MC, Guo H, Davidson D, Mishel S, Lu Y, Rhee I, Pérez-Quintero LA, Zhang S, Cruz-Munoz ME, Wu N, Vinh DC, Sinha M, Calderon V, Lowell CA, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. PMID 28424516 DOI: 10.1038/Nature22076 |
0.443 |
|
| 2017 |
Poh AR, Love CG, Masson F, Preaudet A, Tsui C, Whitehead L, Monard S, Khakham Y, Burstroem L, Lessene G, Sieber O, Lowell C, Putoczki TL, O'Donoghue RJ, Ernst M. Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell. 31: 563-575.e5. PMID 28399411 DOI: 10.1016/J.Ccell.2017.03.006 |
0.404 |
|
| 2017 |
Sinha M, Lowell CA. Efficiency and Specificity of Gene Deletion in Lung Epithelial Doxycycline-Inducible Cre Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 28287822 DOI: 10.1165/Rcmb.2016-0208Oc |
0.374 |
|
| 2017 |
Boras M, Volmering S, Bokemeyer A, Rossaint J, Block H, Bardel B, Van Marck V, Heitplatz B, Kliche S, Reinhold A, Lowell C, Zarbock A. Skap2 is required for β integrin-mediated neutrophil recruitment and functions. The Journal of Experimental Medicine. 214: 851-874. PMID 28183734 DOI: 10.1084/Jem.20160647 |
0.401 |
|
| 2016 |
Lee LM, Ji M, Sinha M, Dong MB, Ren X, Wang Y, Lowell CA, Ghosh S, Locksley RM, DeFranco AL. Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9. Plos One. 11: e0167693. PMID 27977701 DOI: 10.1371/Journal.Pone.0167693 |
0.386 |
|
| 2016 |
Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, et al. Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection. Immunity. PMID 27742545 DOI: 10.1016/J.Immuni.2016.09.012 |
0.41 |
|
| 2016 |
Proekt I, Miller CN, Jeanne M, Fasano KJ, Moon JJ, Lowell CA, Gould DB, Anderson MS, DeFranco AL. LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity. The Journal of Clinical Investigation. PMID 27571405 DOI: 10.1172/Jci84440 |
0.38 |
|
| 2016 |
Hang L, Blum AM, Kumar S, Urban JF, Mitreva M, Geary TG, Jardim A, Stevenson MM, Lowell CA, Weinstock JV. Downregulation of the Syk Signaling Pathway in Intestinal Dendritic Cells Is Sufficient To Induce Dendritic Cells That Inhibit Colitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27559049 DOI: 10.4049/Jimmunol.1600063 |
0.403 |
|
| 2016 |
Wang H, Li M, Hung CY, Sinha M, Lee LM, Wiesner DL, LeBert V, Lerksuthirat T, Galles K, Suresh M, DeFranco AL, Lowell CA, Klein BS, Wüthrich M. MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. Plos Pathogens. 12: e1005787. PMID 27542117 DOI: 10.1371/Journal.Ppat.1005787 |
0.347 |
|
| 2016 |
Németh T, Mócsai A, Lowell CA. Neutrophils in animal models of autoimmune disease. Seminars in Immunology. PMID 27067180 DOI: 10.1016/J.Smim.2016.04.001 |
0.385 |
|
| 2016 |
Kerr SC, Fischer GJ, Sinha M, McCabe O, Palmer JM, Choera T, Yun Lim F, Wimmerova M, Carrington SD, Yuan S, Lowell CA, Oscarson S, Keller NP, Fahy JV. FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. Plos Pathogens. 12: e1005555. PMID 27058347 DOI: 10.1371/Journal.Ppat.1005555 |
0.34 |
|
| 2016 |
Rosales C, Demaurex N, Lowell CA, Uribe-Querol E. Neutrophils: Their Role in Innate and Adaptive Immunity. Journal of Immunology Research. 2016: 1469780. PMID 27006954 DOI: 10.1155/2016/1469780 |
0.409 |
|
| 2016 |
Volmering S, Block H, Boras M, Lowell CA, Zarbock A. The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation. Immunity. 44: 73-87. PMID 26777396 DOI: 10.1016/J.Immuni.2015.11.011 |
0.433 |
|
| 2016 |
Geng H, Gao H, Kadoch C, Lu M, Chen L, Anjum R, Drew L, Degorce S, Dillman K, Mayo M, Anderson S, Collins C, Lowell CA, Rubenstein JL. Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma Blood. 128: 777-777. DOI: 10.1182/Blood.V128.22.777.777 |
0.351 |
|
| 2016 |
Chen Z, Geng H, Lowell CA, Hunger SP, Müschen M. Abstract PR11: Targeted engagement of B cell autoimmunity checkpoints to overcome drug resistance in pediatric Ph-like ALL Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-Pr11 |
0.424 |
|
| 2015 |
Sinha M, Lowell CA. Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 26574781 DOI: 10.1165/Rcmb.2015-0171Oc |
0.44 |
|
| 2015 |
Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 4. PMID 26517880 DOI: 10.7554/Elife.09183 |
0.417 |
|
| 2015 |
Yi T, Li J, Chen H, Wu J, An J, Xu Y, Hu Y, Lowell CA, Cyster JG. Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses. Immunity. PMID 26453377 DOI: 10.1016/J.Immuni.2015.08.021 |
0.358 |
|
| 2015 |
Mazzi P, Caveggion E, Lapinet-Vera JA, Lowell CA, Berton G. The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines. Journal of Immunology (Baltimore, Md. : 1950). 195: 2383-95. PMID 26232427 DOI: 10.4049/Jimmunol.1402011 |
0.398 |
|
| 2015 |
Prakash A, Sundar SV, Zhu YG, Tran A, Lee JW, Lowell C, Hellman J. Lung Ischemia Reperfusion (IR) is a Sterile Inflammatory Process Influenced by Commensal Microbiota in Mice. Shock (Augusta, Ga.). PMID 26196836 DOI: 10.1097/Shk.0000000000000415 |
0.353 |
|
| 2015 |
Stadtmann A, Block H, Volmering S, Abram C, Sohlbach C, Boras M, Lowell CA, Zarbock A. Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment. Journal of Immunology (Baltimore, Md. : 1950). 195: 1152-61. PMID 26101325 DOI: 10.4049/Jimmunol.1500606 |
0.464 |
|
| 2015 |
Mócsai A, Walzog B, Lowell CA. Intracellular signalling during neutrophil recruitment. Cardiovascular Research. 107: 373-85. PMID 25998986 DOI: 10.1093/Cvr/Cvv159 |
0.447 |
|
| 2015 |
Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, ... ... Lowell CA, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 521: 357-61. PMID 25799995 DOI: 10.1038/Nature14231 |
0.449 |
|
| 2015 |
Clemens RA, Lowell CA. Store-operated calcium signaling in neutrophils. Journal of Leukocyte Biology. 98: 497-502. PMID 25714804 DOI: 10.1189/Jlb.2Mr1114-573R |
0.321 |
|
| 2015 |
Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. Author response: LynA regulates an inflammation-sensitive signaling checkpoint in macrophages Elife. DOI: 10.7554/Elife.09183.029 |
0.378 |
|
| 2015 |
Chen Z, Geng H, Lowell CA, Weiss A, Hunger SP, Melnick A, Muschen M. Targeted Activation of B Cell Autoimmunity Checkpoints in Acute Lymphoblastic Leukemia Blood. 126: 3716-3716. DOI: 10.1182/Blood.V126.23.3716.3716 |
0.442 |
|
| 2015 |
Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Loh ML, Jung JU, Coligan JE, Bolland S, ... ... Lowell CA, et al. Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia Cancer Research. 75: 2075-2075. DOI: 10.1158/1538-7445.Am2015-2075 |
0.455 |
|
| 2014 |
Kovács M, Németh T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell CA, Mócsai A. The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment. The Journal of Experimental Medicine. 211: 1993-2011. PMID 25225462 DOI: 10.1084/Jem.20132496 |
0.501 |
|
| 2014 |
Jaumouillé V, Farkash Y, Jaqaman K, Das R, Lowell CA, Grinstein S. Actin cytoskeleton reorganization by syk regulates fcγ receptor responsiveness by increasing its lateral mobility and clustering Developmental Cell. 29: 534-546. PMID 24914558 DOI: 10.1016/J.Devcel.2014.04.031 |
0.343 |
|
| 2014 |
Abram CL, Roberge GL, Hu Y, Lowell CA. Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice. Journal of Immunological Methods. 408: 89-100. PMID 24857755 DOI: 10.1016/J.Jim.2014.05.009 |
0.307 |
|
| 2014 |
Acín-Pérez R, Carrascoso I, Baixauli F, Roche-Molina M, Latorre-Pellicer A, Fernández-Silva P, Mittelbrunn M, Sanchez-Madrid F, Pérez-Martos A, Lowell CA, Manfredi G, Enríquez JA. ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use. Cell Metabolism. 19: 1020-33. PMID 24856931 DOI: 10.1016/J.Cmet.2014.04.015 |
0.348 |
|
| 2014 |
Suzuki R, Leach S, Liu W, Ralston E, Scheffel J, Zhang W, Lowell CA, Rivera J. Molecular editing of cellular responses by the high-affinity receptor for IgE. Science (New York, N.Y.). 343: 1021-5. PMID 24505132 DOI: 10.1126/Science.1246976 |
0.395 |
|
| 2014 |
Zhang H, Clemens RA, Liu F, Hu Y, Baba Y, Theodore P, Kurosaki T, Lowell CA. STIM1 calcium sensor is required for activation of the phagocyte oxidase during inflammation and host defense. Blood. 123: 2238-49. PMID 24493668 DOI: 10.1182/Blood-2012-08-450403 |
0.413 |
|
| 2014 |
Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL. Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 192: 875-85. PMID 24379120 DOI: 10.4049/Jimmunol.1300683 |
0.453 |
|
| 2014 |
Lamagna C, Hu Y, DeFranco AL, Lowell CA. B cell-specific loss of Lyn kinase leads to autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 192: 919-28. PMID 24376269 DOI: 10.4049/Jimmunol.1301979 |
0.44 |
|
| 2014 |
Kadoch C, Li J, Wong VS, Chen L, Cha S, Munster P, Lowell CA, Shuman MA, Rubenstein JL. Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1029-41. PMID 24190981 DOI: 10.1158/1078-0432.Ccr-13-0474 |
0.311 |
|
| 2014 |
Mayadas TN, Cullere X, Lowell CA. The multifaceted functions of neutrophils. Annual Review of Pathology. 9: 181-218. PMID 24050624 DOI: 10.1146/Annurev-Pathol-020712-164023 |
0.387 |
|
| 2014 |
Chen Z, Shojaee S, Geng H, Lee J, Buchner M, Klemm L, Lowell CA, Paietta E, Willman CL, Carroll WL, Melnick A, Jung JU, Jumaa H, Coligan JE, Bolland S, et al. Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia Blood. 124: 792-792. DOI: 10.1182/Blood.V124.21.792.792 |
0.426 |
|
| 2013 |
Graham MT, Abram CL, Hu Y, Lowell CA. Expression of the TEL-Syk fusion protein in hematopoietic stem cells leads to rapidly fatal myelofibrosis in mice. Plos One. 8: e77542. PMID 24116232 DOI: 10.1371/Journal.Pone.0077542 |
0.458 |
|
| 2013 |
Han J, Zhang G, Welch EJ, Liang Y, Fu J, Vogel SM, Lowell CA, Du X, Cheresh DA, Malik AB, Li Z. A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood. 122: 4140-9. PMID 24108461 DOI: 10.1182/Blood-2013-03-491423 |
0.366 |
|
| 2013 |
Albanesi M, Mancardi DA, Jönsson F, Iannascoli B, Fiette L, Di Santo JP, Lowell CA, Bruhns P. Neutrophils mediate antibody-induced antitumor effects in mice. Blood. 122: 3160-4. PMID 23980063 DOI: 10.1182/Blood-2013-04-497446 |
0.354 |
|
| 2013 |
Lamagna C, Scapini P, van Ziffle JA, DeFranco AL, Lowell CA. Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: E3311-20. PMID 23940344 DOI: 10.1073/Pnas.1300617110 |
0.715 |
|
| 2013 |
Vérollet C, Gallois A, Dacquin R, Lastrucci C, Pandruvada SNM, Ortega N, Poincloux R, Behar A, Cougoule C, Lowell C, Al Saati T, Jurdic P, Maridonneau-Parini I. Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors Faseb Journal. 27: 3608-3618. PMID 23742809 DOI: 10.1096/Fj.13-232736 |
0.312 |
|
| 2013 |
Abram CL, Roberge GL, Pao LI, Neel BG, Lowell CA. Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice. Immunity. 38: 489-501. PMID 23521885 DOI: 10.1016/J.Immuni.2013.02.018 |
0.502 |
|
| 2013 |
Fumagalli L, Campa CC, Germena G, Lowell CA, Hirsch E, Berton G. Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation. Journal of Immunology (Baltimore, Md. : 1950). 190: 3648-60. PMID 23447687 DOI: 10.4049/Jimmunol.1201951 |
0.401 |
|
| 2013 |
Heit B, Kim H, Cosío G, Castaño D, Collins R, Lowell CA, Kain KC, Trimble WS, Grinstein S. Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Developmental Cell. 24: 372-83. PMID 23395392 DOI: 10.1016/J.Devcel.2013.01.007 |
0.314 |
|
| 2013 |
Gao H, Anderson S, Kadoch C, Maiti M, Chen L, Yao D, Melkus G, Wang M, Ren Y, Breider M, Heise C, Lowell CA, Collins C, Rubenstein JL. Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy Blood. 122: 374-374. DOI: 10.1182/Blood.V122.21.374.374 |
0.325 |
|
| 2013 |
Chen Z, Shojaee S, Geng H, Lee J, Buchner M, Klemm L, Lowell CA, Paietta E, Willman CL, Carroll WL, Melnick AM, Jung JU, Jumaa H, Coligan JE, Bolland S, et al. Inhibitory Receptors and Phosphatases Enable Oncogenic Tyrosine Kinase Signaling In B Cell Lineage Leukemia Blood. 122: 229-229. DOI: 10.1182/Blood.V122.21.229.229 |
0.449 |
|
| 2012 |
Jhingran A, Mar KB, Kumasaka DK, Knoblaugh SE, Ngo LY, Segal BH, Iwakura Y, Lowell CA, Hamerman JA, Lin X, Hohl TM. Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung. Cell Reports. 2: 1762-73. PMID 23200858 DOI: 10.1016/J.Celrep.2012.10.026 |
0.348 |
|
| 2012 |
Alenghat FJ, Baca QJ, Rubin NT, Pao LI, Matozaki T, Lowell CA, Golan DE, Neel BG, Swanson KD. Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement. Journal of Cell Science. 125: 5535-45. PMID 22976304 DOI: 10.1242/Jcs.111260 |
0.335 |
|
| 2012 |
Ma J, Becker C, Lowell CA, Underhill DM. Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens. The Journal of Biological Chemistry. 287: 34149-56. PMID 22902620 DOI: 10.1074/Jbc.M112.382812 |
0.427 |
|
| 2012 |
Séverin S, Nash CA, Mori J, Zhao Y, Abram C, Lowell CA, Senis YA, Watson SP. Distinct and overlapping functional roles of Src family kinases in mouse platelets. Journal of Thrombosis and Haemostasis : Jth. 10: 1631-45. PMID 22694307 DOI: 10.1111/J.1538-7836.2012.04814.X |
0.403 |
|
| 2012 |
Block H, Herter JM, Rossaint J, Stadtmann A, Kliche S, Lowell CA, Zarbock A. Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury. The Journal of Experimental Medicine. 209: 407-21. PMID 22291096 DOI: 10.1084/Jem.20111493 |
0.46 |
|
| 2012 |
Ni M, MacFarlane AW, Toft M, Lowell CA, Campbell KS, Hamerman JA. B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K. Proceedings of the National Academy of Sciences of the United States of America. 109: 267-72. PMID 22187458 DOI: 10.1073/Pnas.1111957108 |
0.453 |
|
| 2012 |
Xu X, Zhang H, Song Y, Lynch SV, Lowell CA, Wiener-Kronish JP, Caughey GH. Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa. Journal of Leukocyte Biology. 91: 275-84. PMID 22075928 DOI: 10.1189/Jlb.0711356 |
0.386 |
|
| 2012 |
Lowell CA, Mayadas TN. Overview: studying integrins in vivo. Methods in Molecular Biology (Clifton, N.J.). 757: 369-97. PMID 21909923 DOI: 10.1007/978-1-61779-166-6_22 |
0.452 |
|
| 2011 |
Zhu JW, Doan K, Park J, Chau AH, Zhang H, Lowell CA, Weiss A. Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus. Immunity. 35: 757-69. PMID 22078799 DOI: 10.1016/J.Immuni.2011.09.011 |
0.43 |
|
| 2011 |
Elliott ER, Van Ziffle JA, Scapini P, Sullivan BM, Locksley RM, Lowell CA. Deletion of Syk in neutrophils prevents immune complex arthritis. Journal of Immunology (Baltimore, Md. : 1950). 187: 4319-30. PMID 21918195 DOI: 10.4049/Jimmunol.1100341 |
0.68 |
|
| 2011 |
Scapini P, Lamagna C, Hu Y, Lee K, Tang Q, DeFranco AL, Lowell CA. B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 108: E823-32. PMID 21911371 DOI: 10.1073/Pnas.1107913108 |
0.356 |
|
| 2011 |
Andre P, Morooka T, Sim D, Abe K, Lowell C, Nanda N, Delaney S, Siu G, Yan Y, Hollenbach S, Pandey A, Gao H, Wang Y, Nakajima K, Parikh SA, et al. Critical role for Syk in responses to vascular injury. Blood. 118: 5000-10. PMID 21881044 DOI: 10.1182/Blood-2011-06-360743 |
0.334 |
|
| 2011 |
Cai H, Smith DA, Memarzadeh S, Lowell CA, Cooper JA, Witte ON. Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 6579-84. PMID 21464326 DOI: 10.1073/Pnas.1103904108 |
0.37 |
|
| 2011 |
Lowell CA. Neutrophils give us a shock. The Journal of Clinical Investigation. 121: 1260-3. PMID 21436575 DOI: 10.1172/Jci57296 |
0.381 |
|
| 2011 |
Ma G, Pan PY, Eisenstein S, Divino CM, Lowell CA, Takai T, Chen SH. Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells. Immunity. 34: 385-95. PMID 21376641 DOI: 10.1016/J.Immuni.2011.02.004 |
0.399 |
|
| 2011 |
Nelson MP, Christmann BS, Werner JL, Metz AE, Trevor JL, Lowell CA, Steele C. IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina. Journal of Immunology (Baltimore, Md. : 1950). 186: 2372-81. PMID 21220696 DOI: 10.4049/Jimmunol.1002558 |
0.366 |
|
| 2011 |
Kamen LA, Schlessinger J, Lowell CA. Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 186: 1656-65. PMID 21187437 DOI: 10.4049/Jimmunol.1002093 |
0.498 |
|
| 2011 |
Yamada M, Gomez JC, Chugh PE, Lowell CA, Dinauer MC, Dittmer DP, Doerschuk CM. Interferon-γ production by neutrophils during bacterial pneumonia in mice. American Journal of Respiratory and Critical Care Medicine. 183: 1391-401. PMID 21169470 DOI: 10.1164/Rccm.201004-0592Oc |
0.345 |
|
| 2011 |
Lowell CA. Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk. Cold Spring Harbor Perspectives in Biology. 3. PMID 21068150 DOI: 10.1101/Cshperspect.A002352 |
0.458 |
|
| 2011 |
Kadoch C, Wong V, Chen L, Bet-Lachin A, Roy R, Hyun W, Behler C, Lowell C, Rubenstein JL. Dynamic Changes in Macrophage Polarization Correlate with Progression and Response in CNS Lymphoma: Insights Into the Transcriptome of Lymphoma-Associated M2 Macrophages, Blood. 118: 3219-3219. DOI: 10.1182/Blood.V118.21.3219.3219 |
0.329 |
|
| 2010 |
Tavares RM, Turer EE, Liu CL, Advincula R, Scapini P, Rhee L, Barrera J, Lowell CA, Utz PJ, Malynn BA, Ma A. The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. Immunity. 33: 181-91. PMID 20705491 DOI: 10.1016/J.Immuni.2010.07.017 |
0.34 |
|
| 2010 |
Scapini P, Hu Y, Chu CL, Migone TS, Defranco AL, Cassatella MA, Lowell CA. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. The Journal of Experimental Medicine. 207: 1757-73. PMID 20624892 DOI: 10.1084/Jem.20100086 |
0.433 |
|
| 2010 |
Li Z, Zhang G, Liu J, Stojanovic A, Ruan C, Lowell CA, Du X. An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. The Journal of Biological Chemistry. 285: 12559-70. PMID 20189992 DOI: 10.1074/Jbc.M109.098756 |
0.362 |
|
| 2010 |
Baruzzi A, Iacobucci I, Soverini S, Lowell CA, Martinelli G, Berton G. c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration. Febs Letters. 584: 15-21. PMID 19903482 DOI: 10.1016/J.Febslet.2009.11.009 |
0.408 |
|
| 2010 |
Cougoule C, Le Cabec V, Poincloux R, Al Saati T, Mège JL, Tabouret G, Lowell CA, Laviolette-Malirat N, Maridonneau-Parini I. Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis. Blood. 115: 1444-52. PMID 19897576 DOI: 10.1182/Blood-2009-04-218735 |
0.361 |
|
| 2010 |
Ng C, Nahar R, Elliott E, Lowell CA, Muschen M. SYK Is a Tumor Suppressor In Pre-B Cell Acute Lymphoblastic Leukemia and Not a Therapeutic Target Blood. 116: 4199-4199. DOI: 10.1182/Blood.V116.21.4199.4199 |
0.407 |
|
| 2010 |
Duy C, Nowak D, Klemm L, Nahar R, Ng C, Elliott E, Hofmann W, Heisterkamp N, Lowell CA, Koeffler P, Muschen M. Mechanisms of Pre-B Cell Receptor-Inactivation In Acute Lymphoblastic Leukemia Blood. 116: 147-147. DOI: 10.1182/Blood.V116.21.147.147 |
0.418 |
|
| 2010 |
Kadoch C, Wong VS, Rambaldo TC, Hyun WC, Gao HX, Lowell CA, Rubenstein JL. Abstract 5580: Macrophage polarization and acquired resistance to rituximab in CNS lymphoma Cancer Research. 70: 5580-5580. DOI: 10.1158/1538-7445.Am10-5580 |
0.333 |
|
| 2009 |
Hamerman JA, Ni M, Killebrew JR, Chu CL, Lowell CA. The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells. Immunological Reviews. 232: 42-58. PMID 19909355 DOI: 10.1111/J.1600-065X.2009.00841.X |
0.396 |
|
| 2009 |
Looney MR, Nguyen JX, Hu Y, Van Ziffle JA, Lowell CA, Matthay MA. Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. The Journal of Clinical Investigation. 119: 3450-61. PMID 19809160 DOI: 10.1172/Jci38432 |
0.68 |
|
| 2009 |
Van Ziffle JA, Lowell CA. Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection. Blood. 114: 4871-82. PMID 19797524 DOI: 10.1182/Blood-2009-05-220806 |
0.728 |
|
| 2009 |
Abram CL, Lowell CA. Leukocyte adhesion deficiency syndrome: a controversy solved. Immunology and Cell Biology. 87: 440-2. PMID 19417769 DOI: 10.1038/Icb.2009.32 |
0.385 |
|
| 2009 |
Abram CL, Lowell CA. The ins and outs of leukocyte integrin signaling. Annual Review of Immunology. 27: 339-62. PMID 19302044 DOI: 10.1146/Annurev.Immunol.021908.132554 |
0.411 |
|
| 2009 |
Scapini P, Pereira S, Zhang H, Lowell CA. Multiple roles of Lyn kinase in myeloid cell signaling and function. Immunological Reviews. 228: 23-40. PMID 19290919 DOI: 10.1111/J.1600-065X.2008.00758.X |
0.514 |
|
| 2009 |
Kadoch C, Dinca EB, Voicu R, Chen L, Nguyen D, Parikh S, Karrim J, Shuman MA, Lowell CA, Treseler PA, James CD, Rubenstein JL. Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1989-97. PMID 19276270 DOI: 10.1158/1078-0432.Ccr-08-2054 |
0.305 |
|
| 2009 |
Nelson MP, Metz AE, Li S, Lowell CA, Steele C. The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina. Infection and Immunity. 77: 1790-7. PMID 19255189 DOI: 10.1128/Iai.01441-08 |
0.48 |
|
| 2009 |
N'Diaye EN, Branda CS, Branda SS, Nevarez L, Colonna M, Lowell C, Hamerman JA, Seaman WE. TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria. The Journal of Cell Biology. 184: 215-23. PMID 19171755 DOI: 10.1083/Jcb.200808080 |
0.462 |
|
| 2009 |
Miller AL, Zhang C, Shokat KM, Lowell CA. Generation of a novel system for studying spleen tyrosine kinase function in macrophages and B cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 988-98. PMID 19124742 DOI: 10.4049/Jimmunol.182.2.988 |
0.484 |
|
| 2009 |
Kadoch C, Wong VD, Rambaldo T, Hyun W, Lowell C, Rubenstein J. Macrophage Polarization and Acquired Resistance to Rituximab in CNS Lymphoma. Blood. 114: 3749-3749. DOI: 10.1182/Blood.V114.22.3749.3749 |
0.329 |
|
| 2009 |
Hamerman JA, Tchao NK, Lowell CA, Lanier LL. Erratum: Corrigendum: Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12 Nature Immunology. 10: 223-223. DOI: 10.1038/Ni0209-223B |
0.349 |
|
| 2008 |
Sarantos MR, Zhang H, Schaff UY, Dixit N, Hayenga HN, Lowell CA, Simon SI. Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. Journal of Immunology (Baltimore, Md. : 1950). 181: 8660-9. PMID 19050286 DOI: 10.4049/Jimmunol.181.12.8660 |
0.396 |
|
| 2008 |
Ng G, Sharma K, Ward SM, Desrosiers MD, Stephens LA, Schoel WM, Li T, Lowell CA, Ling CC, Amrein MW, Shi Y. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity. 29: 807-18. PMID 18993083 DOI: 10.1016/J.Immuni.2008.09.013 |
0.397 |
|
| 2008 |
Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K. PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling. The Journal of Experimental Medicine. 205: 2339-47. PMID 18794338 DOI: 10.1084/Jem.20072660 |
0.494 |
|
| 2008 |
Liu J, Joglekar M, Ware J, Fitzgerald MEC, Lowell CA, Berndt MC, Gartner TK. Evaluation of the physiological significance of botrocetin/von Willebrand factor in vitro signaling Journal of Thrombosis and Haemostasis. 6: 1915-1922. PMID 18752568 DOI: 10.1111/J.1538-7836.2008.03135.X |
0.38 |
|
| 2008 |
Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase. Journal of Leukocyte Biology. 84: 1141-50. PMID 18625913 DOI: 10.1189/Jlb.0208118 |
0.725 |
|
| 2008 |
Yin H, Liu J, Li Z, Berndt MC, Lowell CA, Du X. Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood. 112: 1139-46. PMID 18550847 DOI: 10.1182/Blood-2008-02-140970 |
0.394 |
|
| 2008 |
Abram CL, Lowell CA. The diverse functions of Src family kinases in macrophages. Frontiers in Bioscience : a Journal and Virtual Library. 13: 4426-50. PMID 18508521 DOI: 10.2741/3015 |
0.463 |
|
| 2008 |
Xiao W, Hong H, Kawakami Y, Lowell CA, Kawakami T. Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5. The Journal of Clinical Investigation. 118: 924-34. PMID 18246197 DOI: 10.1172/Jci34013 |
0.415 |
|
| 2008 |
Chu CL, Yu YL, Shen KY, Lowell CA, Lanier LL, Hamerman JA. Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma. European Journal of Immunology. 38: 166-73. PMID 18081038 DOI: 10.1002/Eji.200737600 |
0.394 |
|
| 2007 |
Jakus Z, Fodor S, Abram CL, Lowell CA, Mócsai A. Immunoreceptor-like signaling by beta 2 and beta 3 integrins. Trends in Cell Biology. 17: 493-501. PMID 17913496 DOI: 10.1016/J.Tcb.2007.09.001 |
0.436 |
|
| 2007 |
Abram CL, Lowell CA. Convergence of immunoreceptor and integrin signaling. Immunological Reviews. 218: 29-44. PMID 17624942 DOI: 10.1111/J.1600-065X.2007.00531.X |
0.492 |
|
| 2007 |
Zarbock A, Lowell CA, Ley K. Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1. Immunity. 26: 773-83. PMID 17543554 DOI: 10.1016/J.Immuni.2007.04.011 |
0.415 |
|
| 2007 |
Hong H, Kitaura J, Xiao W, Horejsi V, Ra C, Lowell CA, Kawakami Y, Kawakami T. The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn. Blood. 110: 2511-9. PMID 17513616 DOI: 10.1182/Blood-2007-01-066092 |
0.476 |
|
| 2007 |
Guo B, Blair D, Chiles TC, Lowell CA, Rothstein TL. Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn. Journal of Immunology (Baltimore, Md. : 1950). 178: 4726-30. PMID 17404251 DOI: 10.4049/Jimmunol.178.8.4726 |
0.393 |
|
| 2007 |
Abram CL, Lowell CA. The expanding role for ITAM-based signaling pathways in immune cells. Science's Stke : Signal Transduction Knowledge Environment. 2007: re2. PMID 17356173 DOI: 10.1126/Stke.3772007Re2 |
0.431 |
|
| 2007 |
Fumagalli L, Zhang H, Baruzzi A, Lowell CA, Berton G. The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine. Journal of Immunology (Baltimore, Md. : 1950). 178: 3874-85. PMID 17339487 DOI: 10.4049/Jimmunol.178.6.3874 |
0.456 |
|
| 2007 |
Evangelista V, Pamuklar Z, Piccoli A, Manarini S, Dell'elba G, Pecce R, Martelli N, Federico L, Rojas M, Berton G, Lowell CA, Totani L, Smyth SS. Src family kinases mediate neutrophil adhesion to adherent platelets. Blood. 109: 2461-9. PMID 17095622 DOI: 10.1182/Blood-2006-06-029082 |
0.389 |
|
| 2006 |
Xu X, Zhang D, Zhang H, Wolters PJ, Killeen NP, Sullivan BM, Locksley RM, Lowell CA, Caughey GH. Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. The Journal of Experimental Medicine. 203: 2907-17. PMID 17158962 DOI: 10.1084/Jem.20061232 |
0.388 |
|
| 2006 |
Mócsai A, Abram CL, Jakus Z, Hu Y, Lanier LL, Lowell CA. Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs. Nature Immunology. 7: 1326-33. PMID 17086186 DOI: 10.1038/Ni1407 |
0.489 |
|
| 2006 |
Zhang H, Schaff UY, Green CE, Chen H, Sarantos MR, Hu Y, Wara D, Simon SI, Lowell CA. Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity. 25: 285-95. PMID 16901726 DOI: 10.1016/J.Immuni.2006.06.014 |
0.366 |
|
| 2006 |
Hirahashi J, Mekala D, Van Ziffle J, Xiao L, Saffaripour S, Wagner DD, Shapiro SD, Lowell C, Mayadas TN. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity. 25: 271-83. PMID 16872848 DOI: 10.1016/J.Immuni.2006.05.014 |
0.722 |
|
| 2006 |
Giagulli C, Ottoboni L, Caveggion E, Rossi B, Lowell C, Constantin G, Laudanna C, Berton G. The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion. Journal of Immunology (Baltimore, Md. : 1950). 177: 604-11. PMID 16785558 DOI: 10.4049/Jimmunol.177.1.604 |
0.405 |
|
| 2006 |
Mermel CH, McLemore ML, Liu F, Pereira S, Woloszynek J, Lowell CA, Link DC. Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis. Blood. 108: 2562-8. PMID 16772601 DOI: 10.1182/Blood-2006-05-024307 |
0.402 |
|
| 2006 |
Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA. Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. The Journal of Clinical Investigation. 116: 1615-23. PMID 16710475 DOI: 10.1172/Jci27238 |
0.645 |
|
| 2006 |
Karur VG, Lowell CA, Besmer P, Agosti V, Wojchowski DM. Lyn kinase promotes erythroblast expansion and late-stage development. Blood. 108: 1524-32. PMID 16705093 DOI: 10.1182/Blood-2005-09-008243 |
0.413 |
|
| 2006 |
Lowell CA. Rewiring phagocytic signal transduction. Immunity. 24: 243-5. PMID 16546092 DOI: 10.1016/J.Immuni.2006.03.002 |
0.354 |
|
| 2006 |
Soriani A, Moran B, de Virgilio M, Kawakami T, Altman A, Lowell C, Eto K, Shattil SJ. A role for PKCtheta in outside-in alpha(IIb)beta3 signaling. Journal of Thrombosis and Haemostasis : Jth. 4: 648-55. PMID 16460447 DOI: 10.1111/J.1538-7836.2006.01806.X |
0.336 |
|
| 2006 |
Sasanuma H, Tatsuno A, Hidano S, Ohshima K, Matsuzaki Y, Hayashi K, Lowell CA, Kitamura D, Goitsuka R. Dual function for the adaptor MIST in IFN-gamma production by NK and CD4+NKT cells regulated by the Src kinase Fgr. Blood. 107: 3647-55. PMID 16439675 DOI: 10.1182/Blood-2005-10-4102 |
0.424 |
|
| 2006 |
Totani L, Piccoli A, Manarini S, Federico L, Pecce R, Martelli N, Cerletti C, Piccardoni P, Lowell CA, Smyth SS, Berton G, Evangelista V. Src-family kinases mediate an outside-in signal necessary for beta2 integrins to achieve full activation and sustain firm adhesion of polymorphonuclear leucocytes tethered on E-selectin. The Biochemical Journal. 396: 89-98. PMID 16433632 DOI: 10.1042/Bj20051924 |
0.405 |
|
| 2006 |
De Franceschi L, Villa-Moruzzi E, Biondani A, Siciliano A, Brugnara C, Alper SL, Lowell CA, Berton G. Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes. PflüGers Archiv : European Journal of Physiology. 451: 760-8. PMID 16283202 DOI: 10.1007/S00424-005-1502-7 |
0.441 |
|
| 2006 |
Zhu QS, Xia L, Mills GB, Lowell CA, Touw IP, Corey SJ. G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. Blood. 107: 1847-56. PMID 16282349 DOI: 10.1182/Blood-2005-04-1612 |
0.375 |
|
| 2005 |
Hernandez-Hansen V, Bard JD, Tarleton CA, Wilder JA, Lowell CA, Wilson BS, Oliver JM. Increased expression of genes linked to FcepsilonRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 7880-8. PMID 16339523 DOI: 10.4049/Jimmunol.175.12.7880 |
0.452 |
|
| 2005 |
Xiao W, Nishimoto H, Hong H, Kitaura J, Nunomura S, Maeda-Yamamoto M, Kawakami Y, Lowell CA, Ra C, Kawakami T. Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI. Journal of Immunology (Baltimore, Md. : 1950). 175: 6885-92. PMID 16272347 DOI: 10.4049/Jimmunol.175.10.6885 |
0.376 |
|
| 2005 |
Lee JY, Lowell CA, Lemay DG, Youn HS, Rhee SH, Sohn KH, Jang B, Ye J, Chung JH, Hwang DH. The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4. Biochemical Pharmacology. 70: 1231-40. PMID 16140274 DOI: 10.1016/J.Bcp.2005.07.020 |
0.426 |
|
| 2005 |
Chu CL, Lowell CA. The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation. Journal of Immunology (Baltimore, Md. : 1950). 175: 2880-9. PMID 16116174 DOI: 10.4049/Jimmunol.175.5.2880 |
0.396 |
|
| 2005 |
Underhill DM, Rossnagle E, Lowell CA, Simmons RM. Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood. 106: 2543-50. PMID 15956283 DOI: 10.1182/Blood-2005-03-1239 |
0.479 |
|
| 2005 |
Hamerman JA, Tchao NK, Lowell CA, Lanier LL. Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12. Nature Immunology. 6: 579-86. PMID 15895090 DOI: 10.1038/Ni1204 |
0.482 |
|
| 2005 |
Kitaura J, Eto K, Kinoshita T, Kawakami Y, Leitges M, Lowell CA, Kawakami T. Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases. Journal of Immunology (Baltimore, Md. : 1950). 174: 4495-504. PMID 15814670 DOI: 10.4049/Jimmunol.174.8.4495 |
0.466 |
|
| 2005 |
Berton G, Mócsai A, Lowell CA. Src and Syk kinases: key regulators of phagocytic cell activation. Trends in Immunology. 26: 208-14. PMID 15797511 DOI: 10.1016/J.It.2005.02.002 |
0.455 |
|
| 2005 |
Zhang H, Meng F, Chu CL, Takai T, Lowell CA. The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B. Immunity. 22: 235-46. PMID 15723811 DOI: 10.1016/J.Immuni.2005.01.004 |
0.468 |
|
| 2005 |
Kitaura J, Kinoshita T, Matsumoto M, Chung S, Kawakami Y, Leitges M, Wu D, Lowell CA, Kawakami T. IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion. Blood. 105: 3222-9. PMID 15637135 DOI: 10.1182/Blood-2004-11-4205 |
0.453 |
|
| 2005 |
Continolo S, Baruzzi A, Majeed M, Caveggion E, Fumagalli L, Lowell CA, Berton G. The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization. Experimental Cell Research. 302: 253-69. PMID 15561106 DOI: 10.1016/J.Yexcr.2004.09.005 |
0.442 |
|
| 2004 |
Pereira S, Zhang H, Takai T, Lowell CA. The inhibitory receptor PIR-B negatively regulates neutrophil and macrophage integrin signaling. Journal of Immunology (Baltimore, Md. : 1950). 173: 5757-65. PMID 15494528 DOI: 10.4049/Jimmunol.173.9.5757 |
0.439 |
|
| 2004 |
Tassiulas I, Hu X, Ho H, Kashyap Y, Paik P, Hu Y, Lowell CA, Ivashkiv LB. Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. Nature Immunology. 5: 1181-9. PMID 15467722 DOI: 10.1038/Ni1126 |
0.386 |
|
| 2004 |
Kitaura J, Xiao W, Maeda-Yamamoto M, Kawakami Y, Lowell CA, Kawakami T. Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival. Journal of Immunology (Baltimore, Md. : 1950). 173: 4317-23. PMID 15383560 DOI: 10.4049/Jimmunol.173.7.4317 |
0.401 |
|
| 2004 |
Jakus Z, Berton G, Ligeti E, Lowell CA, Mócsai A. Responses of neutrophils to anti-integrin antibodies depends on costimulation through low affinity Fc gamma Rs: full activation requires both integrin and nonintegrin signals. Journal of Immunology (Baltimore, Md. : 1950). 173: 2068-77. PMID 15265942 DOI: 10.4049/Jimmunol.173.3.2068 |
0.398 |
|
| 2004 |
Chou WH, Choi DS, Zhang H, Mu D, McMahon T, Kharazia VN, Lowell CA, Ferriero DM, Messing RO. Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury. The Journal of Clinical Investigation. 114: 49-56. PMID 15232611 DOI: 10.1172/Jci21655 |
0.351 |
|
| 2004 |
Lowell CA. Src-family kinases: rheostats of immune cell signaling. Molecular Immunology. 41: 631-43. PMID 15220000 DOI: 10.1016/J.Molimm.2004.04.010 |
0.467 |
|
| 2004 |
Hernandez-Hansen V, Smith AJ, Surviladze Z, Chigaev A, Mazel T, Kalesnikoff J, Lowell CA, Krystal G, Sklar LA, Wilson BS, Oliver JM. Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 100-12. PMID 15210764 DOI: 10.4049/Jimmunol.173.1.100 |
0.494 |
|
| 2004 |
Mócsai A, Humphrey MB, Van Ziffle JA, Hu Y, Burghardt A, Spusta SC, Majumdar S, Lanier LL, Lowell CA, Nakamura MC. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 101: 6158-63. PMID 15073337 DOI: 10.1073/Pnas.0401602101 |
0.702 |
|
| 2004 |
Scapini P, Morini M, Tecchio C, Minghelli S, Di Carlo E, Tanghetti E, Albini A, Lowell C, Berton G, Noonan DM, Cassatella MA. CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A. Journal of Immunology (Baltimore, Md. : 1950). 172: 5034-40. PMID 15067085 DOI: 10.4049/Jimmunol.172.8.5034 |
0.405 |
|
| 2004 |
Hernandez-Hansen V, Mackay GA, Lowell CA, Wilson BS, Oliver JM. The Src kinase Lyn is a negative regulator of mast cell proliferation. Journal of Leukocyte Biology. 75: 143-51. PMID 14525964 DOI: 10.1189/Jlb.0503224 |
0.489 |
|
| 2004 |
Karur V, Vincent B, Lowell C, Wojchowski DM. Lyn Kinase Supports Primary Erythroid Progenitor Cell Development. Blood. 104: 1622-1622. DOI: 10.1182/Blood.V104.11.1622.1622 |
0.409 |
|
| 2003 |
Newbrough SA, Mocsai A, Clemens RA, Wu JN, Silverman MA, Singer AL, Lowell CA, Koretzky GA. SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils. Immunity. 19: 761-9. PMID 14614862 DOI: 10.1016/S1074-7613(03)00305-4 |
0.483 |
|
| 2003 |
Kitaura J, Song J, Tsai M, Asai K, Maeda-Yamamoto M, Mocsai A, Kawakami Y, Liu FT, Lowell CA, Barisas BG, Galli SJ, Kawakami T. Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proceedings of the National Academy of Sciences of the United States of America. 100: 12911-6. PMID 14569021 DOI: 10.1073/Pnas.1735525100 |
0.413 |
|
| 2003 |
Whyburn LR, Halcomb KE, Contreras CM, Lowell CA, Witte ON, Satterthwaite AB. Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 1850-8. PMID 12902486 DOI: 10.4049/Jimmunol.171.4.1850 |
0.445 |
|
| 2003 |
Pereira S, Lowell C. The Lyn tyrosine kinase negatively regulates neutrophil integrin signaling. Journal of Immunology. 171: 1319-1327. PMID 12874221 DOI: 10.4049/Jimmunol.171.3.1319 |
0.486 |
|
| 2003 |
Chen H, Mocsai A, Zhang H, Ding RX, Morisaki JH, White M, Rothfork JM, Heiser P, Colucci-Guyon E, Lowell CA, Gresham HD, Allen PM, Brown EJ. Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading. Immunity. 19: 95-104. PMID 12871642 DOI: 10.1016/S1074-7613(03)00172-9 |
0.44 |
|
| 2003 |
Caveggion E, Continolo S, Pixley FJ, Stanley ER, Bowtell DDL, Lowell CA, Berton G. Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement Journal of Cellular Physiology. 195: 276-289. PMID 12652654 DOI: 10.1002/Jcp.10236 |
0.443 |
|
| 2003 |
Saijo K, Schmedt C, Su IH, Karasuyama H, Lowell CA, Reth M, Adachi T, Patke A, Santana A, Tarakhovsky A. Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nature Immunology. 4: 274-9. PMID 12563261 DOI: 10.1038/Ni893 |
0.455 |
|
| 2003 |
Mócsai A, Zhang H, Jakus Z, Kitaura J, Kawakami T, Lowell CA. G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells. Blood. 101: 4155-63. PMID 12531806 DOI: 10.1182/Blood-2002-07-2346 |
0.493 |
|
| 2003 |
Abtahian F, Guerriero A, Sebzda E, Lu MM, Zhou R, Mocsai A, Myers EE, Huang B, Jackson DG, Ferrari VA, Tybulewicz V, Lowell CA, Lepore JJ, Koretzky GA, Kahn ML. Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science (New York, N.Y.). 299: 247-51. PMID 12522250 DOI: 10.1126/Science.1079477 |
0.354 |
|
| 2002 |
Vicentini L, Mazzi P, Caveggion E, Continolo S, Fumagalli L, Lapinet-Vera JA, Lowell CA, Berton G. Fgr deficiency results in defective eosinophil recruitment to the lung during allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 168: 6446-54. PMID 12055264 DOI: 10.4049/Jimmunol.168.12.6446 |
0.368 |
|
| 2002 |
Mócsai A, Zhou M, Meng F, Tybulewicz VL, Lowell CA. Syk is required for integrin signaling in neutrophils. Immunity. 16: 547-58. PMID 11970878 DOI: 10.1016/S1074-7613(02)00303-5 |
0.456 |
|
| 2002 |
Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ. Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. The Journal of Cell Biology. 157: 265-75. PMID 11940607 DOI: 10.1083/Jcb.200112113 |
0.434 |
|
| 2002 |
Cho MJ, Pestina TI, Steward SA, Lowell CA, Jackson CW, Gartner TK. Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin. Blood. 99: 2442-7. PMID 11895777 DOI: 10.1182/Blood.V99.7.2442 |
0.396 |
|
| 2002 |
Stafford S, Lowell C, Sur S, Alam R. Lyn tyrosine kinase is important for IL-5-stimulated eosinophil differentiation. Journal of Immunology (Baltimore, Md. : 1950). 168: 1978-83. PMID 11823534 DOI: 10.4049/Jimmunol.168.4.1978 |
0.361 |
|
| 2002 |
Dan Q, Sanchez R, Delgado C, Wepsic HT, Morgan K, Chen Y, Jeffes EW, Lowell CA, Morgan TR, Jadus MR. Non-immunogenic murine hepatocellular carcinoma Hepa1-6 cells expressing the membrane form of macrophage colony stimulating factor are rejected in vivo and lead to CD8+ T-cell immunity against the parental tumor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 427-37. PMID 11708879 DOI: 10.1006/Mthe.2001.0477 |
0.385 |
|
| 2001 |
Vines CM, Potter JW, Xu Y, Geahlen RL, Costello PS, Tybulewicz VL, Lowell CA, Chang PW, Gresham HD, Willman CL. Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr. Immunity. 15: 507-19. PMID 11672534 DOI: 10.1016/S1074-7613(01)00221-7 |
0.425 |
|
| 2001 |
Hanna Z, Weng X, Kay DG, Poudrier J, Lowell C, Jolicoeur P. The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck. Journal of Virology. 75: 9378-92. PMID 11533201 DOI: 10.1128/Jvi.75.19.9378-9392.2001 |
0.313 |
|
| 2001 |
Hasegawa M, Fujimoto M, Poe JC, Steeber DA, Lowell CA, Tedder TF. A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 2469-78. PMID 11509585 DOI: 10.4049/Jimmunol.167.5.2469 |
0.397 |
|
| 2001 |
O'Laughlin-Bunner B, Radosevic N, Taylor ML, Shivakrupa, DeBerry C, Metcalfe DD, Zhou M, Lowell C, Linnekin D. Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells. Blood. 98: 343-350. PMID 11435302 DOI: 10.1182/Blood.V98.2.343 |
0.436 |
|
| 2001 |
Pereira S, Zhou M, Mócsai A, Lowell C. Resting murine neutrophils express functional α 4 integrins that signal through Src family kinases Journal of Immunology. 166: 4115-4123. PMID 11238661 DOI: 10.4049/Jimmunol.166.6.4115 |
0.359 |
|
| 2001 |
Yu CCK, Yen TSB, Lowell CA, DeFranco AL. Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn Current Biology. 11: 34-38. PMID 11166177 DOI: 10.1016/S0960-9822(00)00024-5 |
0.401 |
|
| 2001 |
Majeed M, Caveggion E, Lowell CA, Berton G. Role of Src kinases and Syk in Fcγ receptor‐mediated phagocytosis and phagosome‐lysosome fusion Journal of Leukocyte Biology. 70: 801-811. DOI: 10.1189/Jlb.70.5.801 |
0.421 |
|
| 2000 |
Fujimoto M, Fujimoto Y, Poe JC, Jansen PJ, Lowell CA, DeFranco AL, Tedder TF. CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification Immunity. 13: 47-57. PMID 10933394 DOI: 10.1016/S1074-7613(00)00007-8 |
0.397 |
|
| 2000 |
Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, Kawakami T. Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation. Journal of Immunology (Baltimore, Md. : 1950). 165: 1210-9. PMID 10903718 DOI: 10.4049/Jimmunol.165.3.1210 |
0.502 |
|
| 2000 |
Pasquet J, Quek L, Pasquet S, Poole A, Matthews JR, Lowell C, Watson SP. Evidence of a role for SHP-1 in platelet activation by the collagen receptor glycoprotein VI. Journal of Biological Chemistry. 275: 28526-28531. PMID 10871605 DOI: 10.1074/Jbc.M001531200 |
0.418 |
|
| 2000 |
Kawakami Y, Kitaura J, Hartman SE, Lowell CA, Siraganian RP, Kawakami T. Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and Syk. Proceedings of the National Academy of Sciences of the United States of America. 97: 7423-8. PMID 10852954 DOI: 10.1073/Pnas.120175097 |
0.459 |
|
| 2000 |
Satterthwaite AB, Willis F, Kanchanastit P, Fruman D, Cantley LC, Helgason CD, Humphries RK, Lowell CA, Simon M, Leitges M, Tarakhovsky A, Tedder TF, Lesche R, Wu H, Witte ON. A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 97: 6687-92. PMID 10829070 DOI: 10.1073/Pnas.110146697 |
0.491 |
|
| 2000 |
Mócsai A, Jakus Z, Vántus T, Berton G, Lowell CA, Ligeti E. Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases. Journal of Immunology (Baltimore, Md. : 1950). 164: 4321-31. PMID 10754332 DOI: 10.4049/Jimmunol.164.8.4321 |
0.423 |
|
| 2000 |
Weinstein SL, Finn AJ, Davé SH, Meng F, Lowell CA, Sanghera JS, DeFranco AL. Phosphatidylinositol 3-kinase and mTOR mediate lipopolysaccharide-stimulated nitric oxide production in macrophages via interferon-beta. Journal of Leukocyte Biology. 67: 405-14. PMID 10733102 DOI: 10.1002/Jlb.67.3.405 |
0.401 |
|
| 2000 |
Fitzer-Attas CJ, Lowry M, Crowley MT, Finn AJ, Meng F, DeFranco AL, Lowell CA. Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. The Journal of Experimental Medicine. 191: 669-82. PMID 10684859 DOI: 10.1084/Jem.191.4.669 |
0.452 |
|
| 2000 |
Gresham HD, Dale BM, Potter JW, Chang PW, Vines CM, Lowell CA, Lagenaur CF, Willman CL. Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr Journal of Experimental Medicine. 191: 515-528. PMID 10662797 DOI: 10.1084/Jem.191.3.515 |
0.473 |
|
| 2000 |
Quek LS, Pasquet J, Hers I, Cornall R, Knight G, Barnes M, Hibbs ML, Dunn AR, Lowell CA, Watson SP. Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway Blood. 96: 4246-4253. DOI: 10.1182/Blood.V96.13.4246.H8004246_4246_4253 |
0.443 |
|
| 1999 |
Berton G, Lowell CA. Integrin signalling in neutrophils and macrophages. Cellular Signalling. 11: 621-35. PMID 10530871 DOI: 10.1016/S0898-6568(99)00003-0 |
0.448 |
|
| 1999 |
Lowell CA, Berton G. Integrin signal transduction in myeloid leukocytes. Journal of Leukocyte Biology. 65: 313-20. PMID 10080533 DOI: 10.1002/Jlb.65.3.313 |
0.52 |
|
| 1998 |
Satterthwaite AB, Lowell CA, Khan WN, Sideras P, Alt FW, Witte ON. Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways. The Journal of Experimental Medicine. 188: 833-44. PMID 9730885 DOI: 10.1084/Jem.188.5.833 |
0.484 |
|
| 1998 |
DeFranco AL, Chan VWF, Lowell CA. Positive and negative roles of the tyrosine kinase Lyn in B cell function Seminars in Immunology. 10: 299-307. PMID 9695186 DOI: 10.1006/Smim.1998.0122 |
0.451 |
|
| 1998 |
Meng F, Lowell CA. A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration. The Embo Journal. 17: 4391-403. PMID 9687507 DOI: 10.1093/Emboj/17.15.4391 |
0.476 |
|
| 1998 |
Chan VW, Mecklenbräuker I, Su I, Texido G, Leitges M, Carsetti R, Lowell CA, Rajewsky K, Miyake K, Tarakhovsky A. The molecular mechanism of B cell activation by toll-like receptor protein RP-105. The Journal of Experimental Medicine. 188: 93-101. PMID 9653087 DOI: 10.1084/Jem.188.1.93 |
0.464 |
|
| 1998 |
Lowell CA, Berton G. Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr. Proceedings of the National Academy of Sciences of the United States of America. 95: 7580-4. PMID 9636192 DOI: 10.1073/Pnas.95.13.7580 |
0.475 |
|
| 1998 |
Chan VWF, Lowell CA, DeFranco AL. Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes Current Biology. 8: 545-553. PMID 9601638 DOI: 10.1016/S0960-9822(98)70223-4 |
0.483 |
|
| 1997 |
Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, Varmus HE. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes & Development. 11: 2835-44. PMID 9353253 DOI: 10.1101/Gad.11.21.2835 |
0.454 |
|
| 1997 |
Crowley MT, Costello PS, Fitzer-Attas CJ, Turner M, Meng F, Lowell C, Tybulewicz VL, DeFranco AL. A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. The Journal of Experimental Medicine. 186: 1027-39. PMID 9314552 DOI: 10.1084/Jem.186.7.1027 |
0.527 |
|
| 1997 |
Chan VWF, Meng F, Soriano P, DeFranco AL, Lowell CA. Characterization of the B lymphocyte populations in lyn-deficient mice and the role of lyn in signal initiation and down-regulation Immunity. 7: 69-81. PMID 9252121 DOI: 10.1016/S1074-7613(00)80511-7 |
0.442 |
|
| 1997 |
Meng F, Lowell CA. Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn Journal of Experimental Medicine. 185: 1661-1670. PMID 9151903 DOI: 10.1084/Jem.185.9.1661 |
0.449 |
|
| 1997 |
De Franceschi L, Fumagalli L, Olivieri O, Corrocher R, Lowell CA, Berton G. Deficiency of Src family kinases Fgr and Hck results in activation of erythrocyte K/Cl cotransport. The Journal of Clinical Investigation. 99: 220-7. PMID 9005990 DOI: 10.1172/Jci119150 |
0.337 |
|
| 1997 |
Berton G, Yan SR, Fumagalli L, Lowell CA. Neutrophil activation by adhesion: mechanisms and pathophysiological implications. International Journal of Clinical & Laboratory Research. 26: 160-77. PMID 8905448 DOI: 10.1007/Bf02592978 |
0.404 |
|
| 1996 |
Lowell CA, Soriano P. Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories. Genes & Development. 10: 1845-57. PMID 8756343 DOI: 10.1101/Gad.10.15.1845 |
0.32 |
|
| 1996 |
Lowell CA, Fumagalli L, Berton G. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. The Journal of Cell Biology. 133: 895-910. PMID 8666673 DOI: 10.1083/Jcb.133.4.895 |
0.458 |
|
| 1996 |
Lowell CA, Niwa M, Soriano P, Varmus HE. Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood. 87: 1780-92. PMID 8634424 DOI: 10.1182/Blood.V87.5.1780.Bloodjournal8751780 |
0.435 |
|
| 1994 |
Lowell CA, Soriano P, Varmus HE. Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes & Development. 8: 387-98. PMID 8125254 DOI: 10.1101/Gad.8.4.387 |
0.369 |
|
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