| Year |
Citation |
Score |
| 2024 |
Bell RD, Cann EA, Mishra B, Valencia M, Zhang Q, Huang M, Yang X, Carli A, Bostrom M, Ivashkiv LB. Staphyloccocus aureus biofilm, in absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 38922976 DOI: 10.1002/jor.25919 |
0.791 |
|
| 2024 |
Mishra B, Ivashkiv LB. Interferons and epigenetic mechanisms in training, priming and tolerance of monocytes and hematopoietic progenitors. Immunological Reviews. PMID 38567833 DOI: 10.1111/imr.13330 |
0.799 |
|
| 2023 |
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Falco MM, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, et al. Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. Research Square. PMID 38168227 DOI: 10.21203/rs.3.rs-3683989/v1 |
0.732 |
|
| 2023 |
Yang C, Yuan R, Brauner C, Du Y, Ah Kioon MD, Barrat FJ, Ivashkiv LB. Dichotomous roles of RIPK3 in regulating the IFN response and NLRP3 inflammasome in human monocytes. Journal of Leukocyte Biology. PMID 37648661 DOI: 10.1093/jleuko/qiad095 |
0.48 |
|
| 2023 |
Herrero C, Hu X, Li WP, Samuels S, Sharif MN, Kotenko S, Ivashkiv LB. Expressions of Concern: Reprogramming of IL-10 Activity and Signaling by IFN-γ. Journal of Immunology (Baltimore, Md. : 1950). 211: 164. PMID 37339406 DOI: 10.4049/jimmunol.2300295 |
0.333 |
|
| 2023 |
Hu X, Park-Min KH, Ho HH, Ivashkiv LB. Correction: IFN-γ-Primed Macrophages Exhibit Increased CCR2-Dependent Migration and Altered IFN-γ Responses Mediated by Stat1. Journal of Immunology (Baltimore, Md. : 1950). PMID 36883848 DOI: 10.4049/jimmunol.2300060 |
0.696 |
|
| 2022 |
Murata K, Fang C, Terao C, Giannopoulou EG, Lee YJ, Lee MJ, Mun SH, Bae S, Qiao Y, Yuan R, Furu M, Ito H, Ohmura K, Matsuda S, Mimori T, ... ... Ivashkiv LB, et al. Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. Immunity. 55: 2209. PMID 36351378 DOI: 10.1016/j.immuni.2022.10.007 |
0.67 |
|
| 2022 |
Laurent P, Yang C, Rendeiro AF, Nilsson-Payant BE, Carrau L, Chandar V, Bram Y, tenOever BR, Elemento O, Ivashkiv LB, Schwartz RE, Barrat FJ. Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19. Science Immunology. 7: eadd4906. PMID 36083891 DOI: 10.1126/sciimmunol.add4906 |
0.341 |
|
| 2022 |
Yang C, Bachu M, Du Y, Brauner C, Yuan R, Ah Kioon MD, Chesi G, Barrat FJ, Ivashkiv LB. CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes. Nature Communications. 13: 3426. PMID 35701499 DOI: 10.1038/s41467-022-31132-7 |
0.457 |
|
| 2022 |
Du Y, Ah Kioon MD, Laurent P, Chaudhary V, Pierides M, Yang C, Oliver D, Ivashkiv LB, Barrat FJ. Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. The Journal of Experimental Medicine. 219. PMID 35640018 DOI: 10.1084/jem.20212142 |
0.339 |
|
| 2022 |
Doi K, Murata K, Ito S, Suzuki A, Terao C, Ishie S, Umemoto A, Murotani Y, Nishitani K, Yoshitomi H, Fujii T, Watanabe R, Hashimoto M, Murakami K, Tanaka M, ... ... Ivashkiv LB, et al. LSD1 metabolically integrates osteoclast differentiation and inflammatory bone resorption through HIF-1α and E2F1. Arthritis & Rheumatology (Hoboken, N.J.). PMID 35077015 DOI: 10.1002/art.42074 |
0.678 |
|
| 2021 |
Fujii T, Murata K, Mun SH, Bae S, Lee YJ, Pannellini T, Kang K, Oliver D, Park-Min KH, Ivashkiv LB. MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS. Bone Research. 9: 4. PMID 33424022 DOI: 10.1038/s41413-020-00120-2 |
0.789 |
|
| 2019 |
Ivashkiv LB. The hypoxia-lactate axis tempers inflammation. Nature Reviews. Immunology. PMID 31819164 DOI: 10.1038/S41577-019-0259-8 |
0.481 |
|
| 2019 |
Barrat FJ, Crow MK, Ivashkiv LB. Interferon target-gene expression and epigenomic signatures in health and disease. Nature Immunology. 20: 1574-1583. PMID 31745335 DOI: 10.1038/S41590-019-0466-2 |
0.508 |
|
| 2019 |
Kang K, Bachu M, Park SH, Kang K, Bae S, Park-Min KH, Ivashkiv LB. IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation. Nature Communications. 10: 3320. PMID 31346169 DOI: 10.1038/S41467-019-11147-3 |
0.836 |
|
| 2019 |
Kusnadi A, Park SH, Yuan R, Pannellini T, Giannopoulou E, Oliver D, Lu T, Park-Min KH, Ivashkiv LB. The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair. Immunity. PMID 31303399 DOI: 10.1016/J.Immuni.2019.06.005 |
0.8 |
|
| 2019 |
Loh C, Park SH, Lee A, Yuan R, Ivashkiv LB, Kalliolias GD. TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis. Annals of the Rheumatic Diseases. PMID 31097419 DOI: 10.1136/Annrheumdis-2018-214783 |
0.658 |
|
| 2019 |
Kuo D, Ding J, Cohn IS, Zhang F, Wei K, Rao DA, Rozo C, Sokhi UK, Shanaj S, Oliver DJ, Echeverria AP, DiCarlo EF, Brenner MB, Bykerk VP, Goodman SM, ... ... Ivashkiv LB, et al. HBEGF macrophages in rheumatoid arthritis induce fibroblast invasiveness. Science Translational Medicine. 11. PMID 31068444 DOI: 10.1126/Scitranslmed.Aau8587 |
0.426 |
|
| 2019 |
Donlin LT, Park SH, Giannopoulou E, Ivovic A, Park-Min KH, Siegel RM, Ivashkiv LB. Insights into rheumatic diseases from next-generation sequencing. Nature Reviews. Rheumatology. PMID 31000790 DOI: 10.1038/S41584-019-0217-7 |
0.708 |
|
| 2018 |
Ivashkiv LB. IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy. Nature Reviews. Immunology. PMID 29921905 DOI: 10.1038/S41577-018-0029-Z |
0.513 |
|
| 2018 |
Manni M, Gupta S, Ricker E, Chinenov Y, Park SH, Shi M, Pannellini T, Jessberger R, Ivashkiv LB, Pernis AB. Regulation of age-associated B cells by IRF5 in systemic autoimmunity. Nature Immunology. PMID 29483597 DOI: 10.1038/S41590-018-0056-8 |
0.63 |
|
| 2018 |
Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, ... ... Ivashkiv LB, et al. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nature Communications. 9: 789. PMID 29476097 DOI: 10.1038/S41467-018-02892-Y |
0.382 |
|
| 2018 |
Sokhi UK, Liber MP, Frye L, Park S, Kang K, Pannellini T, Zhao B, Norinsky R, Ivashkiv LB, Gong S. Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nature Communications. 9: 658. PMID 29440643 DOI: 10.1038/S41467-018-03081-7 |
0.8 |
|
| 2017 |
Park SH, Kang K, Giannopoulou E, Qiao Y, Kang K, Kim G, Park-Min KH, Ivashkiv LB. Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation. Nature Immunology. PMID 28825701 DOI: 10.1038/Ni.3818 |
0.843 |
|
| 2017 |
Kang K, Park SH, Chen J, Qiao Y, Giannopoulou E, Berg K, Hanidu A, Li J, Nabozny G, Kang K, Park-Min KH, Ivashkiv LB. Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF. Immunity. 47: 235-250.e4. PMID 28813657 DOI: 10.1016/J.Immuni.2017.07.017 |
0.822 |
|
| 2017 |
Murata K, Fang C, Terao C, Giannopoulou EG, Lee YJ, Lee MJ, Mun SH, Bae S, Qiao Y, Yuan R, Furu M, Ito H, Ohmura K, Matsuda S, Mimori T, ... ... Ivashkiv LB, et al. Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. Immunity. 47: 66-79.e5. PMID 28723554 DOI: 10.1016/J.Immuni.2017.06.018 |
0.765 |
|
| 2017 |
Loupasakis K, Kuo D, Sokhi UK, Sohn C, Syracuse B, Giannopoulou EG, Park SH, Kang H, Rätsch G, Ivashkiv LB, Kalliolias GD. Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes. Plos One. 12: e0179762. PMID 28708839 DOI: 10.1371/Journal.Pone.0179762 |
0.654 |
|
| 2017 |
Binder N, Miller C, Yoshida M, Inoue K, Nakano S, Hu X, Ivashkiv LB, Schett G, Pernis A, Goldring SR, Ross FP, Zhao B. Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption. Journal of Immunology (Baltimore, Md. : 1950). PMID 28314855 DOI: 10.4049/Jimmunol.1601716 |
0.466 |
|
| 2017 |
Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, ... ... Ivashkiv LB, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 542: 110-114. PMID 28150777 DOI: 10.1038/Nature20810 |
0.348 |
|
| 2017 |
Loupasakis K, Kuo D, Sohn C, Syracuse B, Giannopoulou EG, Park SH, Rätsch G, Ivashkiv LB, Kalliolias GD. 04.10 Chronic inflammation regulates the mrna stabilome in rheumatoid arthritis fibroblast-like synoviocytes Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211051.10 |
0.458 |
|
| 2016 |
Qiao Y, Kang K, Giannopoulou E, Fang C, Ivashkiv LB. IFN-γ Induces Histone 3 Lysine 27 Trimethylation in a Small Subset of Promoters to Stably Silence Gene Expression in Human Macrophages. Cell Reports. 16: 3121-9. PMID 27653678 DOI: 10.1016/J.Celrep.2016.08.051 |
0.81 |
|
| 2016 |
Huynh L, Kusnadi A, Park SH, Murata K, Park-Min KH, Ivashkiv LB. Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Scientific Reports. 6: 31959. PMID 27558590 DOI: 10.1038/Srep31959 |
0.843 |
|
| 2016 |
Ivashkiv LB, Park SH. Epigenetic Regulation of Myeloid Cells. Microbiology Spectrum. 4. PMID 27337441 DOI: 10.1128/Microbiolspec.Mchd-0010-2015 |
0.613 |
|
| 2016 |
Miller CH, Smith SM, Elguindy M, Zhang T, Xiang JZ, Hu X, Ivashkiv LB, Zhao B. RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183593 DOI: 10.4049/Jimmunol.1502044 |
0.396 |
|
| 2016 |
Fang C, Qiao Y, Mun SH, Lee MJ, Murata K, Bae S, Zhao B, Park-Min KH, Ivashkiv LB. Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183582 DOI: 10.4049/Jimmunol.1501466 |
0.693 |
|
| 2016 |
Foldi J, Shang Y, Zhao B, Ivashkiv LB, Hu X. RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes. Protein & Cell. PMID 26874522 DOI: 10.1007/S13238-016-0248-7 |
0.725 |
|
| 2016 |
Kalliolias GD, Ivashkiv LB. TNF biology, pathogenic mechanisms and emerging therapeutic strategies. Nature Reviews. Rheumatology. 12: 49-62. PMID 26656660 DOI: 10.1038/Nrrheum.2015.169 |
0.492 |
|
| 2015 |
Lee MJ, Lim E, Mun S, Bae S, Murata K, Ivashkiv LB, Park-Min KH. Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression. Journal of Cellular Physiology. PMID 26189496 DOI: 10.1002/Jcp.25091 |
0.75 |
|
| 2015 |
Su X, Yu Y, Zhong Y, Giannopoulou EG, Hu X, Liu H, Cross JR, Rätsch G, Rice CM, Ivashkiv LB. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nature Immunology. 16: 838-49. PMID 26147685 DOI: 10.1038/Ni.3205 |
0.499 |
|
| 2015 |
Giannopoulou EG, Elemento O, Ivashkiv LB. Use of RNA sequencing to evaluate rheumatic disease patients. Arthritis Research & Therapy. 17: 167. PMID 26126608 DOI: 10.1186/S13075-015-0677-3 |
0.302 |
|
| 2015 |
Ivashkiv LB. Metabolic-epigenetic coupling in osteoclast differentiation. Nature Medicine. 21: 212-3. PMID 25742453 DOI: 10.1038/Nm.3815 |
0.362 |
|
| 2015 |
Chan CH, Fang C, Qiao Y, Yarilina A, Prinjha RK, Ivashkiv LB. BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes. European Journal of Immunology. 45: 287-97. PMID 25345375 DOI: 10.1002/Eji.201444862 |
0.575 |
|
| 2015 |
Sohn C, Lee A, Qiao Y, Loupasakis K, Ivashkiv LB, Kalliolias GD. Prolonged tumor necrosis factor α primes fibroblast-like synoviocytes in a gene-specific manner by altering chromatin. Arthritis & Rheumatology (Hoboken, N.J.). 67: 86-95. PMID 25199798 DOI: 10.1002/Art.38871 |
0.388 |
|
| 2015 |
Qiao Y, Ivashkiv LB. Effect and mechanism of BET bromodomain inhibition in macrophage transcriptional programming Inflammation and Cell Signaling. 1. DOI: 10.14800/Ics.600 |
0.541 |
|
| 2014 |
Park-Min KH, Lim E, Lee MJ, Park SH, Giannopoulou E, Yarilina A, van der Meulen M, Zhao B, Smithers N, Witherington J, Lee K, Tak PP, Prinjha RK, Ivashkiv LB. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nature Communications. 5: 5418. PMID 25391636 DOI: 10.1038/Ncomms6418 |
0.787 |
|
| 2014 |
Li S, Miller CH, Giannopoulou E, Hu X, Ivashkiv LB, Zhao B. RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis. The Journal of Clinical Investigation. 124: 5057-73. PMID 25329696 DOI: 10.1172/Jci71882 |
0.468 |
|
| 2014 |
Donlin LT, Jayatilleke A, Giannopoulou EG, Kalliolias GD, Ivashkiv LB. Modulation of TNF-induced macrophage polarization by synovial fibroblasts. Journal of Immunology (Baltimore, Md. : 1950). 193: 2373-83. PMID 25057003 DOI: 10.4049/Jimmunol.1400486 |
0.569 |
|
| 2014 |
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 41: 14-20. PMID 25035950 DOI: 10.1016/J.Immuni.2014.06.008 |
0.381 |
|
| 2014 |
Ivashkiv LB, Donlin LT. Regulation of type I interferon responses. Nature Reviews. Immunology. 14: 36-49. PMID 24362405 DOI: 10.1038/Nri3581 |
0.481 |
|
| 2014 |
Sohn C, Loupasakis K, Lee A, Ivashkiv L, Kalliolias G. THU0535 Chronic TNF Alpha Primes Fibroblast-Like Synoviocytes in A Gene-Specific Manner by Removing the Chromatin Barrier Annals of the Rheumatic Diseases. 73: 368.1-368. DOI: 10.1136/Annrheumdis-2014-Eular.4536 |
0.472 |
|
| 2014 |
Chakravarty S, Au K, Ivashkiv L, Hu X. FRI0363 Deletion of RBP-J in A Murine Model of Inflammatory Arthritis Reveals Pro-Inflammatory Cytokine Expression and Immunophenotypic Differences Annals of the Rheumatic Diseases. 73: 518.2-518. DOI: 10.1136/Annrheumdis-2014-Eular.1086 |
0.494 |
|
| 2014 |
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, et al. Correction tp Macrophage activation and polarization: Nomenclature and experimental guidelines [Immunity, 41, 2014 (14-20)] Immunity. 41: 339-340. DOI: 10.1016/J.Immuni.2014.07.009 |
0.332 |
|
| 2013 |
Qiao Y, Giannopoulou EG, Chan CH, Park SH, Gong S, Chen J, Hu X, Elemento O, Ivashkiv LB. Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling. Immunity. 39: 454-69. PMID 24012417 DOI: 10.1016/J.Immuni.2013.08.009 |
0.731 |
|
| 2013 |
Ivashkiv LB. PTPN22 in autoimmunity: different cell and different way. Immunity. 39: 91-3. PMID 23890067 DOI: 10.1016/J.Immuni.2013.07.007 |
0.379 |
|
| 2013 |
Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, et al. iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. The Journal of Clinical Investigation. 123: 928-32. PMID 23348744 DOI: 10.1172/Jci66168 |
0.734 |
|
| 2013 |
Lee A, Qiao Y, Grigoriev G, Chen J, Park-Min KH, Park SH, Ivashkiv LB, Kalliolias GD. Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts. Arthritis and Rheumatism. 65: 928-38. PMID 23335080 DOI: 10.1002/Art.37853 |
0.815 |
|
| 2013 |
Ivashkiv LB. Epigenetic regulation of macrophage polarization and function. Trends in Immunology. 34: 216-23. PMID 23218730 DOI: 10.1016/J.It.2012.11.001 |
0.457 |
|
| 2013 |
Park-Min KH, Lee EY, Moskowitz NK, Lim E, Lee SK, Lorenzo JA, Huang C, Melnick AM, Purdue PE, Goldring SR, Ivashkiv LB. Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 135-49. PMID 22893614 DOI: 10.1002/Jbmr.1739 |
0.746 |
|
| 2013 |
Chakravarty SD, Au K, Hu X, Ivashkiv LB. A3.25 Deletion of RBP-J in a Murine Model of Inflammatory Arthritis Reveals Differential Pro-Inflammatory Cytokine and FoxP3 Gene Expression Annals of the Rheumatic Diseases. 72: A22.3-A23. DOI: 10.1136/annrheumdis-2013-203216.25 |
0.333 |
|
| 2013 |
Smith S, Shang Y, Xu H, Zhu J, Zhao B, Shi C, Kageyama R, Ivashkiv LB, Hu X. 250 Cytokine. 63: 302. DOI: 10.1016/J.Cyto.2013.06.253 |
0.578 |
|
| 2013 |
Ivashkiv LB. 129 Cytokine. 63: 273. DOI: 10.1016/J.Cyto.2013.06.132 |
0.578 |
|
| 2012 |
Yarilina A, Xu K, Chan C, Ivashkiv LB. Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors. Arthritis and Rheumatism. 64: 3856-66. PMID 22941906 DOI: 10.1002/Art.37691 |
0.408 |
|
| 2012 |
Gordon RA, Grigoriev G, Lee A, Kalliolias GD, Ivashkiv LB. The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor α and counter-regulated by the synovial fluid microenvironment. Arthritis and Rheumatism. 64: 3119-28. PMID 22614743 DOI: 10.1002/Art.34544 |
0.495 |
|
| 2012 |
Xu H, Zhu J, Smith S, Foldi J, Zhao B, Chung AY, Outtz H, Kitajewski J, Shi C, Weber S, Saftig P, Li Y, Ozato K, Blobel CP, Ivashkiv LB, et al. Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nature Immunology. 13: 642-50. PMID 22610140 DOI: 10.1038/Ni.2304 |
0.787 |
|
| 2012 |
Huynh L, Wang L, Shi C, Park-Min KH, Ivashkiv LB. ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 188: 3447-57. PMID 22368279 DOI: 10.4049/Jimmunol.1102211 |
0.821 |
|
| 2012 |
Zhao B, Grimes SN, Li S, Hu X, Ivashkiv LB. TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J. The Journal of Experimental Medicine. 209: 319-34. PMID 22249448 DOI: 10.1084/Jem.20111566 |
0.489 |
|
| 2012 |
Yarilina A, Xu K, Chan C, Ivashkiv LB. Regulation of macrophage-mediated chronic inflammation by JAK inhibitors Arthritis Research & Therapy. 14: P78. DOI: 10.1186/Ar3679 |
0.538 |
|
| 2012 |
Kalliolias GD, Chen J, Grigoriev G, Ivashkiv LB. Synovial fibroblasts display an uncontrolled inflammatory and tissue destructive response to TNF-α Arthritis Research & Therapy. 14. DOI: 10.1186/Ar3591 |
0.375 |
|
| 2012 |
Ivashkiv LB. New mechanisms of action and signaling by TNF-α Arthritis Research & Therapy. 14. DOI: 10.1186/Ar3590 |
0.513 |
|
| 2012 |
Triantafyllopoulou A, Ivashkiv L. Macrophage activation in polyinosinic:polycytidylic acid-accelerated murine lupus nephritis Annals of the Rheumatic Diseases. 71: A78.2-A79. DOI: 10.1136/Annrheumdis-2011-201238.15 |
0.437 |
|
| 2012 |
Su X, Ivashkiv L. P138 Crosstalk between ITAM and IFN-gamma signaling mediated by GSK3 Cytokine. 59: 563. DOI: 10.1016/J.Cyto.2012.06.230 |
0.545 |
|
| 2011 |
Ivashkiv LB, Zhao B, Park-Min KH, Takami M. Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8. Annals of the New York Academy of Sciences. 1237: 88-94. PMID 22082370 DOI: 10.1111/J.1749-6632.2011.06217.X |
0.758 |
|
| 2011 |
Ivashkiv LB. Inflammatory signaling in macrophages: transitions from acute to tolerant and alternative activation states. European Journal of Immunology. 41: 2477-81. PMID 21952800 DOI: 10.1002/Eji.201141783 |
0.466 |
|
| 2011 |
Zhao B, Ivashkiv LB. Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors. Arthritis Research & Therapy. 13: 234. PMID 21861861 DOI: 10.1186/Ar3379 |
0.382 |
|
| 2011 |
Park SH, Park-Min KH, Chen J, Hu X, Ivashkiv LB. Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages. Nature Immunology. 12: 607-15. PMID 21602809 DOI: 10.1038/Ni.2043 |
0.798 |
|
| 2011 |
Ivashkiv LB. How ITAMs inhibit signaling. Science Signaling. 4: pe20. PMID 21505184 DOI: 10.1126/Scisignal.2001917 |
0.401 |
|
| 2011 |
Bethunaickan R, Berthier CC, Ramanujam M, Sahu R, Zhang W, Sun Y, Bottinger EP, Ivashkiv L, Kretzler M, Davidson A. A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis. Journal of Immunology (Baltimore, Md. : 1950). 186: 4994-5003. PMID 21411733 DOI: 10.4049/Jimmunol.1003010 |
0.353 |
|
| 2011 |
Antoniv TT, Ivashkiv LB. Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway. Immunology. 132: 567-77. PMID 21255011 DOI: 10.1111/J.1365-2567.2010.03402.X |
0.501 |
|
| 2011 |
Yarilina A, Xu K, Chen J, Ivashkiv LB. TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages. Proceedings of the National Academy of Sciences of the United States of America. 108: 1573-8. PMID 21220349 DOI: 10.1073/Pnas.1010030108 |
0.522 |
|
| 2011 |
Yuan W, DiMartino SJ, Redecha PB, Ivashkiv LB, Salmon JE. Systemic lupus erythematosus monocytes are less responsive to interleukin-10 in the presence of immune complexes. Arthritis and Rheumatism. 63: 212-8. PMID 20954190 DOI: 10.1002/Art.30083 |
0.367 |
|
| 2011 |
Ivashkiv L, Park S, Chen J. CS11-6. Repression of Inflammatory Cytokine Genes by TNF- and IFNg-regulated Signaling and Epigenetic Mechanisms Cytokine. 56: 61. DOI: 10.1016/J.Cyto.2011.07.374 |
0.689 |
|
| 2010 |
Chen J, Ivashkiv LB. IFN-γ abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling. Proceedings of the National Academy of Sciences of the United States of America. 107: 19438-43. PMID 20974955 DOI: 10.1073/Pnas.1007816107 |
0.57 |
|
| 2010 |
Kalliolias GD, Gordon RA, Ivashkiv LB. Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27. Journal of Immunology (Baltimore, Md. : 1950). 185: 7047-56. PMID 20971923 DOI: 10.4049/Jimmunol.1001290 |
0.47 |
|
| 2010 |
Lee B, Kim TH, Jun JB, Yoo DH, Woo JH, Choi SJ, Lee YH, Song GG, Sohn J, Park-Min KH, Ivashkiv LB, Ji JD. Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta. Journal of Immunology (Baltimore, Md. : 1950). 185: 5926-34. PMID 20935210 DOI: 10.4049/Jimmunol.1001591 |
0.722 |
|
| 2010 |
Leslie K, Gao SP, Berishaj M, Podsypanina K, Ho H, Ivashkiv L, Bromberg J. Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation. Breast Cancer Research : Bcr. 12: R80. PMID 20929542 DOI: 10.1186/Bcr2725 |
0.412 |
|
| 2010 |
Ho HH, Ivashkiv LB. Downregulation of Friend leukemia virus integration 1 as a feedback mechanism that restrains lipopolysaccharide induction of matrix metalloproteases and interleukin-10 in human macrophages. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 893-900. PMID 20879862 DOI: 10.1089/Jir.2010.0046 |
0.464 |
|
| 2010 |
Foldi J, Chung AY, Xu H, Zhu J, Outtz HH, Kitajewski J, Li Y, Hu X, Ivashkiv LB. Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. Journal of Immunology (Baltimore, Md. : 1950). 185: 5023-31. PMID 20870935 DOI: 10.4049/Jimmunol.1001544 |
0.776 |
|
| 2010 |
Ivashkiv LB. STAT activation during viral infection in vivo: where's the interferon? Cell Host & Microbe. 8: 132-5. PMID 20709291 DOI: 10.1016/J.Chom.2010.07.011 |
0.426 |
|
| 2010 |
Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, Rogatsky I. The type I interferon signaling pathway is a target for glucocorticoid inhibition. Molecular and Cellular Biology. 30: 4564-74. PMID 20679482 DOI: 10.1128/Mcb.00146-10 |
0.537 |
|
| 2010 |
James DE, Nestor BJ, Sculco TP, Ivashkiv LB, Ross FP, Goldring SR, Purdue PE. The relative timing of exposure to phagocytosable particulates and to osteoclastogenic cytokines is critically important in the determination of myeloid cell fate. Journal of Immunology (Baltimore, Md. : 1950). 185: 1265-73. PMID 20543106 DOI: 10.4049/Jimmunol.0902808 |
0.491 |
|
| 2010 |
Kelly EK, Wang L, Ivashkiv LB. Calcium-activated pathways and oxidative burst mediate zymosan-induced signaling and IL-10 production in human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 5545-52. PMID 20400701 DOI: 10.4049/Jimmunol.0901293 |
0.488 |
|
| 2010 |
Kalliolias GD, Ivashkiv LB. Overview of the biology of type I interferons. Arthritis Research & Therapy. 12: S1. PMID 20392288 DOI: 10.1186/Ar2881 |
0.405 |
|
| 2010 |
Wang L, Gordon RA, Huynh L, Su X, Park Min KH, Han J, Arthur JS, Kalliolias GD, Ivashkiv LB. Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins. Immunity. 32: 518-30. PMID 20362473 DOI: 10.1016/J.Immuni.2010.03.014 |
0.75 |
|
| 2010 |
Yarilina A, Ivashkiv LB. Type I interferon: a new player in TNF signaling. Current Directions in Autoimmunity. 11: 94-104. PMID 20173389 DOI: 10.1159/000289199 |
0.532 |
|
| 2010 |
Triantafyllopoulou A, Franzke CW, Seshan SV, Perino G, Kalliolias GD, Ramanujam M, van Rooijen N, Davidson A, Ivashkiv LB. Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages. Proceedings of the National Academy of Sciences of the United States of America. 107: 3012-7. PMID 20133703 DOI: 10.1073/Pnas.0914902107 |
0.374 |
|
| 2010 |
Kalliolias GD, Zhao B, Triantafyllopoulou A, Park-Min KH, Ivashkiv LB. Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling. Arthritis and Rheumatism. 62: 402-13. PMID 20112358 DOI: 10.1002/Art.27200 |
0.728 |
|
| 2010 |
Xu H, Zhu J, Foldi J, Chung AY, Shi C, Li Y, Ivashkiv LB, Hu X. PS2-44 Notch signaling regulates interleukin-12 expression via interferon regulatory factor 8 Cytokine. 52: 59. DOI: 10.1016/J.Cyto.2010.07.249 |
0.749 |
|
| 2010 |
Flammer JR, Kennedy MA, Chinenov Y, Ivashkiv LB, Rogatsky I. PS1-56 Type I interferon-dependent gene expression is a target for glucocorticoid inhibition Cytokine. 52: 29. DOI: 10.1016/J.Cyto.2010.07.128 |
0.361 |
|
| 2010 |
Xu H, Zhu J, Foldi J, Chung AY, Outtz H, Kitajewski J, Kageyama R, Gessler M, Li Y, Ivashkiv LB, Hu X. SS3-3 Positive and negative regulation of cytokine expression by Notch pathway Cytokine. 52: 15. DOI: 10.1016/J.Cyto.2010.07.067 |
0.732 |
|
| 2009 |
Kalliolias GD, Ivashkiv LB. Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammation. F1000 Biology Reports. 1: 70. PMID 20948617 DOI: 10.3410/B1-70 |
0.395 |
|
| 2009 |
Ji JD, Park-Min KH, Shen Z, Fajardo RJ, Goldring SR, McHugh KP, Ivashkiv LB. Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors. Journal of Immunology (Baltimore, Md. : 1950). 183: 7223-33. PMID 19890054 DOI: 10.4049/Jimmunol.0900072 |
0.758 |
|
| 2009 |
Hu X, Ivashkiv LB. Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity. 31: 539-50. PMID 19833085 DOI: 10.1016/J.Immuni.2009.09.002 |
0.555 |
|
| 2009 |
Zhao B, Takami M, Yamada A, Wang X, Koga T, Hu X, Tamura T, Ozato K, Choi Y, Ivashkiv LB, Takayanagi H, Kamijo R. Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nature Medicine. 15: 1066-71. PMID 19718038 DOI: 10.1038/Nm.2007 |
0.449 |
|
| 2009 |
Park-Min KH, Ji JD, Antoniv T, Reid AC, Silver RB, Humphrey MB, Nakamura M, Ivashkiv LB. IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression. Journal of Immunology (Baltimore, Md. : 1950). 183: 2444-55. PMID 19625651 DOI: 10.4049/Jimmunol.0804165 |
0.741 |
|
| 2009 |
Ji JD, Park-Min KH, Ivashkiv LB. Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Human Immunology. 70: 211-7. PMID 19480842 DOI: 10.1016/J.Humimm.2009.01.026 |
0.739 |
|
| 2009 |
Ivashkiv LB. Cross-regulation of signaling by ITAM-associated receptors. Nature Immunology. 10: 340-7. PMID 19295630 DOI: 10.1038/Ni.1706 |
0.416 |
|
| 2009 |
Ji JD, Ivashkiv LB. Roles of semaphorins in the immune and hematopoietic system. Rheumatology International. 29: 727-34. PMID 19139899 DOI: 10.1007/S00296-009-0852-4 |
0.356 |
|
| 2009 |
Foldi J, Hu X, Ivashkiv LB. Regulation and function of notch ligands in macrophages Cytokine. 48: 38. DOI: 10.1016/J.Cyto.2009.07.345 |
0.719 |
|
| 2008 |
Hu X, Chakravarty SD, Ivashkiv LB. Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms. Immunological Reviews. 226: 41-56. PMID 19161415 DOI: 10.1111/J.1600-065X.2008.00707.X |
0.573 |
|
| 2008 |
Hu X, Chung AY, Wu I, Foldi J, Chen J, Ji JD, Tateya T, Kang YJ, Han J, Gessler M, Kageyama R, Ivashkiv LB. Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity. 29: 691-703. PMID 18976936 DOI: 10.1016/J.Immuni.2008.08.016 |
0.803 |
|
| 2008 |
Ho HH, Antoniv TT, Ji JD, Ivashkiv LB. Lipopolysaccharide-induced expression of matrix metalloproteinases in human monocytes is suppressed by IFN-gamma via superinduction of ATF-3 and suppression of AP-1. Journal of Immunology (Baltimore, Md. : 1950). 181: 5089-97. PMID 18802113 DOI: 10.4049/Jimmunol.181.7.5089 |
0.456 |
|
| 2008 |
Ivashkiv LB. A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways. Nature Reviews. Immunology. 8: 816-22. PMID 18787561 DOI: 10.1038/Nri2396 |
0.426 |
|
| 2008 |
Hu Y, Park-Min KH, Yarilina A, Ivashkiv LB. Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2. Journal of Leukocyte Biology. 84: 1353-60. PMID 18678606 DOI: 10.1189/Jlb.0107040 |
0.743 |
|
| 2008 |
Hu Y, Hu X, Boumsell L, Ivashkiv LB. IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways. Journal of Immunology (Baltimore, Md. : 1950). 180: 8057-65. PMID 18523269 DOI: 10.4049/Jimmunol.180.12.8057 |
0.516 |
|
| 2008 |
Kalliolias GD, Ivashkiv LB. IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38. Journal of Immunology (Baltimore, Md. : 1950). 180: 6325-33. PMID 18424756 DOI: 10.4049/Jimmunol.180.9.6325 |
0.442 |
|
| 2008 |
Yarilina A, Park-Min KH, Antoniv T, Hu X, Ivashkiv LB. TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes. Nature Immunology. 9: 378-87. PMID 18345002 DOI: 10.1038/Ni1576 |
0.773 |
|
| 2008 |
DiMartino SJ, Yuan W, Redecha P, Ivashkiv LB, Salmon JE. Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a. Clinical Immunology (Orlando, Fla.). 127: 56-65. PMID 18201931 DOI: 10.1016/J.Clim.2007.11.014 |
0.382 |
|
| 2008 |
Wang L, Tassiulas I, Park-Min KH, Reid AC, Gil-Henn H, Schlessinger J, Baron R, Zhang JJ, Ivashkiv LB. 'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages. Nature Immunology. 9: 186-93. PMID 18084294 DOI: 10.1038/Ni1548 |
0.741 |
|
| 2008 |
Koulouvaris P, Ly K, Ivashkiv LB, Bostrom MP, Nestor BJ, Sculco TP, Purdue PE. Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 106-16. PMID 17729302 DOI: 10.1002/Jor.20486 |
0.519 |
|
| 2008 |
Flammer JR, Kennedy MA, Chinenov Y, Ivashkiv LB, Rogatsky I. 187 Glucocorticoid regulation of the type I interferon-JAK/STAT signaling pathway Cytokine. 43: 283-284. DOI: 10.1016/J.Cyto.2008.07.249 |
0.401 |
|
| 2007 |
Hu X, Chen J, Wang L, Ivashkiv LB. Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. Journal of Leukocyte Biology. 82: 237-43. PMID 17502339 DOI: 10.1189/Jlb.1206763 |
0.552 |
|
| 2007 |
Zhu W, Boachie-Adjei O, Rawlins BA, Frenkel B, Boskey AL, Ivashkiv LB, Blobel CP. A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells. The Journal of Biological Chemistry. 282: 18676-85. PMID 17439946 DOI: 10.1074/Jbc.M610232200 |
0.418 |
|
| 2007 |
Tassiulas I, Park-Min KH, Hu Y, Kellerman L, Mevorach D, Ivashkiv LB. Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages. Human Immunology. 68: 156-64. PMID 17349870 DOI: 10.1016/J.Humimm.2006.12.008 |
0.773 |
|
| 2007 |
Yarilina A, DiCarlo E, Ivashkiv LB. Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs. Journal of Immunology (Baltimore, Md. : 1950). 178: 2204-11. PMID 17277125 DOI: 10.4049/Jimmunol.178.4.2204 |
0.477 |
|
| 2007 |
Park-Min KH, Serbina NV, Yang W, Ma X, Krystal G, Neel BG, Nutt SL, Hu X, Ivashkiv LB. FcγRIII-Dependent Inhibition of Interferon-γ Responses Mediates Suppressive Effects of Intravenous Immune Globulin Immunity. 26: 67-78. PMID 17239631 DOI: 10.1016/J.Immuni.2006.11.010 |
0.748 |
|
| 2006 |
Antoniv TT, Ivashkiv LB. Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages. Arthritis and Rheumatism. 54: 2711-21. PMID 16947381 DOI: 10.1002/Art.22055 |
0.482 |
|
| 2006 |
Rakshit DS, Lim JT, Ly K, Ivashkiv LB, Nestor BJ, Sculco TP, Purdue PE. Involvement of complement receptor 3 (CR3) and scavenger receptor in macrophage responses to wear debris. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 2036-44. PMID 16947312 DOI: 10.1002/Jor.20275 |
0.365 |
|
| 2006 |
Sharif MN, Sosic D, Rothlin CV, Kelly E, Lemke G, Olson EN, Ivashkiv LB. Twist mediates suppression of inflammation by type I IFNs and Axl. The Journal of Experimental Medicine. 203: 1891-901. PMID 16831897 DOI: 10.1084/Jem.20051725 |
0.513 |
|
| 2006 |
Rogatsky I, Ivashkiv LB. Glucocorticoid modulation of cytokine signaling. Tissue Antigens. 68: 1-12. PMID 16774534 DOI: 10.1111/J.1399-0039.2006.00599.X |
0.535 |
|
| 2006 |
Hu X, Paik PK, Chen J, Yarilina A, Kockeritz L, Lu TT, Woodgett JR, Ivashkiv LB. IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity. 24: 563-74. PMID 16713974 DOI: 10.1016/J.Immuni.2006.02.014 |
0.528 |
|
| 2006 |
Hu Y, Ivashkiv LB. Costimulation of chemokine receptor signaling by matrix metalloproteinase-9 mediates enhanced migration of IFN-alpha dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 6022-33. PMID 16670311 DOI: 10.4049/Jimmunol.176.10.6022 |
0.394 |
|
| 2006 |
Rakshit DS, Ly K, Sengupta TK, Nestor BJ, Sculco TP, Ivashkiv LB, Purdue PE. Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis. The Journal of Bone and Joint Surgery. American Volume. 88: 788-99. PMID 16595469 DOI: 10.2106/Jbjs.E.00711 |
0.499 |
|
| 2006 |
Du Z, Kelly E, Mecklenbräuker I, Agle L, Herrero C, Paik P, Ivashkiv LB. Selective regulation of IL-10 signaling and function by zymosan. Journal of Immunology (Baltimore, Md. : 1950). 176: 4785-92. PMID 16585572 DOI: 10.4049/Jimmunol.176.8.4785 |
0.78 |
|
| 2006 |
Ho HH, Ivashkiv LB. Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation. The Journal of Biological Chemistry. 281: 14111-8. PMID 16571725 DOI: 10.1074/Jbc.M511797200 |
0.526 |
|
| 2005 |
Rosenkranz ME, Schulte DJ, Agle LM, Wong MH, Zhang W, Ivashkiv L, Doherty TM, Fishbein MC, Lehman TJ, Michelsen KS, Arditi M. TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease. Circulation. 112: 2966-73. PMID 16275884 DOI: 10.1161/Circulationaha.105.537530 |
0.378 |
|
| 2005 |
Sun W, Xu W, Snyder M, He W, Ho H, Ivashkiv LB, Zhang JJ. The conserved Leu-724 residue is required for both serine phosphorylation and co-activator recruitment for Stat1-mediated transcription activation in response to interferon-gamma. The Journal of Biological Chemistry. 280: 41844-51. PMID 16257975 DOI: 10.1074/Jbc.M505797200 |
0.403 |
|
| 2005 |
Antoniv TT, Park-Min KH, Ivashkiv LB. Kinetics of IL-10-induced gene expression in human macrophages. Immunobiology. 210: 87-95. PMID 16164015 DOI: 10.1016/J.Imbio.2005.05.003 |
0.742 |
|
| 2005 |
Park-Min KH, Antoniv TT, Ivashkiv LB. Regulation of macrophage phenotype by long-term exposure to IL-10. Immunobiology. 210: 77-86. PMID 16164014 DOI: 10.1016/J.Imbio.2005.05.002 |
0.723 |
|
| 2005 |
Hu X, Park-Min KH, Ho HH, Ivashkiv LB. IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1. Journal of Immunology (Baltimore, Md. : 1950). 175: 3637-47. PMID 16148108 DOI: 10.4049/Jimmunol.175.6.3637 |
0.756 |
|
| 2005 |
Du Z, Shen Y, Yang W, Mecklenbrauker I, Neel BG, Ivashkiv LB. Inhibition of IFN-α signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway Proceedings of the National Academy of Sciences of the United States of America. 102: 10267-10272. PMID 16000408 DOI: 10.1073/Pnas.0408854102 |
0.767 |
|
| 2005 |
Hu X, Ho HH, Lou O, Hidaka C, Ivashkiv LB. Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction. Journal of Immunology (Baltimore, Md. : 1950). 175: 131-8. PMID 15972639 DOI: 10.4049/Jimmunol.175.1.131 |
0.513 |
|
| 2004 |
Tassiulas I, Hu X, Ho H, Kashyap Y, Paik P, Hu Y, Lowell CA, Ivashkiv LB. Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. Nature Immunology. 5: 1181-9. PMID 15467722 DOI: 10.1038/Ni1126 |
0.507 |
|
| 2004 |
Ivashkiv LB, Hu X. Signaling by STATs. Arthritis Research & Therapy. 6: 159-68. PMID 15225360 DOI: 10.1186/Ar1197 |
0.476 |
|
| 2004 |
Sharif MN, Tassiulas I, Hu Y, Mecklenbräuker I, Tarakhovsky A, Ivashkiv LB. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 172: 6476-81. PMID 15128840 DOI: 10.4049/Jimmunol.172.10.6476 |
0.479 |
|
| 2003 |
Ivashkiv LB. Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesis. Autoimmunity. 36: 473-9. PMID 14984024 DOI: 10.1080/08916930310001605882 |
0.468 |
|
| 2003 |
Herrero C, Hu X, Li WP, Samuels S, Sharif MN, Kotenko S, Ivashkiv LB. Reprogramming of IL-10 activity and signaling by IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 171: 5034-41. PMID 14607900 DOI: 10.4049/Jimmunol.171.10.5034 |
0.527 |
|
| 2003 |
Ivashkiv LB, Hu X. The JAK/STAT pathway in rheumatoid arthritis: pathogenic or protective? Arthritis and Rheumatism. 48: 2092-6. PMID 12905460 DOI: 10.1002/Art.11095 |
0.353 |
|
| 2003 |
Ji JD, Tassiulas I, Park-Min KH, Aydin A, Mecklenbrauker I, Tarakhovsky A, Pricop L, Salmon JE, Ivashkiv LB. Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis. The Journal of Experimental Medicine. 197: 1573-83. PMID 12782719 DOI: 10.1084/Jem.20021820 |
0.752 |
|
| 2003 |
Hu X, Li WP, Meng C, Ivashkiv LB. Inhibition of IFN-gamma signaling by glucocorticoids. Journal of Immunology (Baltimore, Md. : 1950). 170: 4833-9. PMID 12707366 DOI: 10.4049/Jimmunol.170.9.4833 |
0.507 |
|
| 2003 |
Ivashkiv LB, Tassiulas I. Can SOCS make arthritis better? The Journal of Clinical Investigation. 111: 795-7. PMID 12639982 DOI: 10.1172/Jci18113 |
0.453 |
|
| 2002 |
Krause A, Scaletta N, Ji JD, Ivashkiv LB. Rheumatoid arthritis synoviocyte survival is dependent on Stat3. Journal of Immunology (Baltimore, Md. : 1950). 169: 6610-6. PMID 12444174 DOI: 10.4049/Jimmunol.169.11.6610 |
0.4 |
|
| 2002 |
Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, Woods JM, Haines GK, Ivashkiv LB. Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation. Nature Immunology. 3: 859-66. PMID 12172544 DOI: 10.1038/Ni828 |
0.476 |
|
| 2002 |
Ahmed ST, Mayer A, Ji JD, Ivashkiv LB. Inhibition of IL-6 signaling by a p38-dependent pathway occurs in the absence of new protein synthesis. Journal of Leukocyte Biology. 72: 154-62. PMID 12101275 DOI: 10.1189/Jlb.72.1.154 |
0.456 |
|
| 2001 |
Deon D, Ahmed S, Tai K, Scaletta N, Herrero C, Lee IH, Krause A, Ivashkiv LB. Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts. Journal of Immunology (Baltimore, Md. : 1950). 167: 5395-403. PMID 11673558 DOI: 10.4049/Jimmunol.167.9.5395 |
0.474 |
|
| 2000 |
Ahmed ST, Ivashkiv LB. Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways. Journal of Immunology (Baltimore, Md. : 1950). 165: 5227-37. PMID 11046056 DOI: 10.4049/Jimmunol.165.9.5227 |
0.47 |
|
| 2000 |
Bianchi M, Meng C, Ivashkiv LB. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. 97: 9573-8. PMID 10920190 DOI: 10.1073/Pnas.160099797 |
0.459 |
|
| 1999 |
Lee IH, Li WP, Hisert KB, Ivashkiv LB. Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion. The Journal of Experimental Medicine. 190: 1263-74. PMID 10544198 DOI: 10.1084/Jem.190.9.1263 |
0.448 |
|
| 1998 |
Sengupta TK, Talbot ES, Scherle PA, Ivashkiv LB. Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 95: 11107-12. PMID 9736697 DOI: 10.1073/Pnas.95.19.11107 |
0.464 |
|
| 1997 |
Ivashkiv LB. Cytokine expression and cell activation in inflammatory arthritis. Advances in Immunology. 63: 337-76. PMID 8787634 DOI: 10.1016/S0065-2776(08)60859-7 |
0.456 |
|
| 1996 |
Sengupta TK, Schmitt EM, Ivashkiv LB. Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 93: 9499-9504. PMID 8790359 DOI: 10.1073/Pnas.93.18.9499 |
0.507 |
|
| 1995 |
Glimcher LH, Ivashkiv LB. Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins. American Journal of Therapeutics. 2: 676. PMID 11854845 DOI: 10.1097/00045391-199509000-00016 |
0.331 |
|
| 1995 |
Sengupta TK, Chen A, Zhong Z, Darnell JE, Ivashkiv LB. Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma. The Journal of Experimental Medicine. 181: 1015-25. PMID 7869026 DOI: 10.1084/Jem.181.3.1015 |
0.508 |
|
| 1995 |
Ivashkiv LB. Cytokines and STATs: how can signals achieve specificity? Immunity. 3: 1-4. PMID 7621070 DOI: 10.1016/1074-7613(95)90152-3 |
0.429 |
|
| 1995 |
Wang F, Sengupta TK, Zhong Z, Ivashkiv LB. Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids Journal of Experimental Medicine. 182: 1825-1831. PMID 7500028 DOI: 10.1084/Jem.182.6.1825 |
0.548 |
|
| 1994 |
Ivashkiv LB, Ayres A, Glimcher LH. Inhibition of IFN-γ induction of class II MHC genes by cAMP and prostaglandins Immunopharmacology. 27: 67-77. PMID 8206755 DOI: 10.1016/0162-3109(94)90008-6 |
0.417 |
|
| 1991 |
Whitley MZ, Sisk R, Ivashkiv LB, Finn PW, Glimcher LH, Boothby MR. Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha. International Immunology. 3: 877-88. PMID 1931814 DOI: 10.1093/Intimm/3.9.877 |
0.325 |
|
| 1991 |
Ivashkiv LB, Glimcher LH. Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements Journal of Experimental Medicine. 174: 1583-1592. PMID 1660527 DOI: 10.1084/Jem.174.6.1583 |
0.394 |
|
| 1990 |
Kara CJ, Liou HC, Ivashkiv LB, Glimcher LH. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain Molecular and Cellular Biology. 10: 1347-1357. PMID 2320002 DOI: 10.1128/Mcb.10.4.1347 |
0.3 |
|
| 1990 |
Ivashkiv LB, Liou HC, Kara CJ, Lamph WW, Verma IM, Glimcher LH. mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Molecular and Cellular Biology. 10: 1609-21. PMID 2138707 DOI: 10.1128/Mcb.10.4.1609 |
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| 1989 |
Wiren KM, Ivashkiv L, Ma P, Freeman MW, Potts JT, Kronenberg HM. Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties Molecular Endocrinology. 3: 240-250. PMID 2710131 DOI: 10.1210/Mend-3-2-240 |
0.302 |
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