Year |
Citation |
Score |
2024 |
Rahman MM, Tollefsbol TO. Combinatorial phenethyl isothiocyanate and withaferin A targets multiple epigenetics pathways to inhibit MCF-7 and MDA-MB-231 human breast cancer cells. Cancer Cell International. 24: 422. PMID 39707321 DOI: 10.1186/s12935-024-03619-4 |
0.345 |
|
2024 |
Rahman MM, Tollefsbol TO. dCas9-HDAC8-EGFP fusion enables epigenetic editing of breast cancer cells by H3K9 deacetylation. European Journal of Cell Biology. 103: 151463. PMID 39437453 DOI: 10.1016/j.ejcb.2024.151463 |
0.42 |
|
2024 |
Rahman MM, Wu H, Tollefsbol TO. A novel combinatorial approach using sulforaphane- and withaferin A-rich extracts for prevention of estrogen receptor-negative breast cancer through epigenetic and gut microbial mechanisms. Scientific Reports. 14: 12091. PMID 38802425 DOI: 10.1038/s41598-024-62084-1 |
0.314 |
|
2023 |
Witt BL, Tollefsbol TO. Molecular, Cellular, and Technical Aspects of Breast Cancer Cell Lines as a Foundational Tool in Cancer Research. Life (Basel, Switzerland). 13. PMID 38137912 DOI: 10.3390/life13122311 |
0.311 |
|
2023 |
Wu H, Van Der Pol WJ, Dubois LG, Morrow CD, Tollefsbol TO. Dietary Supplementation of Inulin Contributes to the Prevention of Estrogen Receptor-Negative Mammary Cancer by Alteration of Gut Microbial Communities and Epigenetic Regulations. International Journal of Molecular Sciences. 24. PMID 37240357 DOI: 10.3390/ijms24109015 |
0.309 |
|
2023 |
Brane A, Arora I, Tollefsbol TO. Peripubertal Nutritional Prevention of Cancer-Associated Gene Expression and Phenotypes. Cancers. 15. PMID 36765634 DOI: 10.3390/cancers15030674 |
0.306 |
|
2022 |
Arora I, Li S, Crowley MR, Li Y, Tollefsbol TO. Genome-Wide Analysis on Transcriptome and Methylome in Prevention of Mammary Tumor Induced by Early Life Combined Botanicals. Cells. 12. PMID 36611809 DOI: 10.3390/cells12010014 |
0.375 |
|
2022 |
Sharma M, Tollefsbol TO. Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. Experimental Cell Research. 416: 113160. PMID 35447103 DOI: 10.1016/j.yexcr.2022.113160 |
0.397 |
|
2022 |
Arora I, Sharma M, Li S, Crowley M, Crossman DK, Li Y, Tollefsbol TO. An integrated analysis of the effects of maternal broccoli sprouts exposure on transcriptome and methylome in prevention of offspring mammary cancer. Plos One. 17: e0264858. PMID 35263365 DOI: 10.1371/journal.pone.0264858 |
0.302 |
|
2022 |
Chen M, Li S, Srinivasasainagendra V, Sharma M, Li Z, Tiwari H, Tollefsbol TO, Li Y. Maternal soybean genistein on prevention of later-life breast cancer through inherited epigenetic regulations. Carcinogenesis. PMID 35084457 DOI: 10.1093/carcin/bgac009 |
0.302 |
|
2021 |
Sharma M, Arora I, Chen M, Wu H, Crowley MR, Tollefsbol TO, Li Y. Therapeutic Effects of Dietary Soybean Genistein on Triple-Negative Breast Cancer via Regulation of Epigenetic Mechanisms. Nutrients. 13. PMID 34836197 DOI: 10.3390/nu13113944 |
0.369 |
|
2021 |
Ganguly S, Arora I, Tollefsbol TO. Impact of Stilbenes as Epigenetic Modulators of Breast Cancer Risk and Associated Biomarkers. International Journal of Molecular Sciences. 22. PMID 34576196 DOI: 10.3390/ijms221810033 |
0.338 |
|
2021 |
Arora I, Li Y, Sharma M, Crowley MR, Crossman DK, Li S, Tollefsbol TO. Systematic integrated analyses of methylomic and transcriptomic impacts of early combined botanicals on estrogen receptor-negative mammary cancer. Scientific Reports. 11: 9481. PMID 33947955 DOI: 10.1038/s41598-021-89131-5 |
0.306 |
|
2020 |
Li S, Wu H, Tollefsbol TO. Combined Broccoli Sprouts and Green Tea Polyphenols Contribute to the Prevention of Estrogen Receptor-Negative Mammary Cancer via Cell Cycle Arrest and Inducing Apoptosis in HER2/neu Mice. The Journal of Nutrition. PMID 33188406 DOI: 10.1093/jn/nxaa315 |
0.303 |
|
2020 |
Arora I, Sharma M, Sun LY, Tollefsbol TO. The Epigenetic Link between Polyphenols, Aging and Age-Related Diseases. Genes. 11. PMID 32962067 DOI: 10.3390/Genes11091094 |
0.426 |
|
2020 |
Arora I, Tollefsbol TO. Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications. Methods (San Diego, Calif.). PMID 32941995 DOI: 10.1016/J.Ymeth.2020.09.008 |
0.411 |
|
2020 |
Rahman MM, Tollefsbol TO. Targeting cancer epigenetics with CRISPR-dCAS9: Principles and prospects. Methods (San Diego, Calif.). PMID 32315755 DOI: 10.1016/J.Ymeth.2020.04.006 |
0.411 |
|
2020 |
Li S, Chen M, Wu H, Li Y, Tollefsbol TO. Maternal epigenetic regulation contributes to prevention of estrogen receptor-negative mammary cancer with broccoli sprout consumption. Cancer Prevention Research (Philadelphia, Pa.). PMID 32184225 DOI: 10.1158/1940-6207.Capr-19-0491 |
0.485 |
|
2020 |
Steed KL, Jordan HR, Tollefsbol TO. SAHA and EGCG Promote Apoptosis in Triple-negative Breast Cancer Cells, Possibly Through the Modulation of cIAP2. Anticancer Research. 40: 9-26. PMID 31892549 DOI: 10.21873/Anticanres.13922 |
0.434 |
|
2020 |
Lewis KA, Tollefsbol TO. Abstract B046: SAHA and EGCG reduce breast cancer migration, possibly through modulation of cIAP2 Cancer Epidemiology, Biomarkers & Prevention. DOI: 10.1158/1538-7755.Disp18-B046 |
0.336 |
|
2019 |
Sharma M, Li Y, Stoll ML, Tollefsbol TO. The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes. Frontiers in Genetics. 10: 1329. PMID 32010189 DOI: 10.3389/Fgene.2019.01329 |
0.328 |
|
2019 |
Rahman MM, Brane AC, Tollefsbol TO. MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer. Cells. 8. PMID 31597272 DOI: 10.3390/Cells8101214 |
0.46 |
|
2019 |
Arora I, Sharma M, Tollefsbol TO. Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy. International Journal of Molecular Sciences. 20. PMID 31540128 DOI: 10.3390/Ijms20184567 |
0.453 |
|
2019 |
Akinyemiju T, Salako O, Daramola A, Alatise O, Adeniyi A, Ogun G, Ayandipo O, Olajide T, Olasehinde O, Arowolo O, Adisa A, Afuwape O, Olusanya A, Adegoke A, Ojo A, ... Tollefsbol T, et al. Collaborative Molecular Epidemiology Study of Metabolic Dysregulation, DNA Methylation, and Breast Cancer Risk Among Nigerian Women: MEND Study Objectives and Design. Journal of Global Oncology. 5: 1-9. PMID 31194608 DOI: 10.1200/Jgo.18.00226 |
0.377 |
|
2019 |
Li S, Chen M, Li Y, Tollefsbol TO. Prenatal epigenetics diets play protective roles against environmental pollution. Clinical Epigenetics. 11: 82. PMID 31097039 DOI: 10.1186/S13148-019-0659-4 |
0.332 |
|
2019 |
Brane AC, Tollefsbol TO. Targeting Telomeres and Telomerase: Studies in Aging and Disease Utilizing CRISPR/Cas9 Technology. Cells. 8. PMID 30795542 DOI: 10.3390/Cells8020186 |
0.366 |
|
2019 |
Li Y, Chen M, Li S, Tollefsbol T. Abstract 1605: Time-dependent maternal soybean genistein exposure leads to later-life breast cancer chemoprevention in mice Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1605 |
0.313 |
|
2018 |
Lewis KA, Jordan HR, Tollefsbol TO. Effects of SAHA and EGCG on Growth Potentiation of Triple-Negative Breast Cancer Cells. Cancers. 11. PMID 30591655 DOI: 10.3390/Cancers11010023 |
0.447 |
|
2018 |
Gao Y, Tollefsbol TO. Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery. International Journal of Molecular Sciences. 19. PMID 30060527 DOI: 10.3390/Ijms19082204 |
0.522 |
|
2018 |
Paul B, Li Y, Tollefsbol TO. The Effects of Combinatorial Genistein and Sulforaphane in Breast Tumor Inhibition: Role in Epigenetic Regulation. International Journal of Molecular Sciences. 19. PMID 29899271 DOI: 10.3390/Ijms19061754 |
0.471 |
|
2018 |
Li Y, Buckhaults P, Li S, Tollefsbol TO. Temporal efficacy of a sulforaphane-based broccoli sprout diet in prevention of breast cancer through modulation of epigenetic mechanisms. Cancer Prevention Research (Philadelphia, Pa.). PMID 29764806 DOI: 10.1158/1940-6207.Capr-17-0423 |
0.42 |
|
2018 |
Royston KJ, Paul B, Nozell S, Rajbhandari R, Tollefsbol TO. Withaferin A and Sulforaphane Regulate Breast Cancer Cell Cycle Progression through Epigenetic Mechanisms. Experimental Cell Research. PMID 29689276 DOI: 10.1016/J.Yexcr.2018.04.015 |
0.506 |
|
2018 |
Martin SL, Royston KJ, Tollefsbol TO. The Role of Non-coding RNAs and Isothiocyanates in Cancer. Molecular Nutrition & Food Research. PMID 29532604 DOI: 10.1002/Mnfr.201700913 |
0.404 |
|
2018 |
Lewis KA, Tollefsbol TO. Abstract A67: The effects of SAHA and EGCG on metastatic potential in triple-negative breast cancer Cancer Epidemiology, Biomarkers & Prevention. 27. DOI: 10.1158/1538-7755.Disp17-A67 |
0.432 |
|
2017 |
García-Giménez JL, Seco-Cervera M, Tollefsbol TO, Romá-Mateo C, Peiró-Chova L, Lapunzina P, Pallardó FV. Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory. Critical Reviews in Clinical Laboratory Sciences. 54: 529-550. PMID 29226748 DOI: 10.1080/10408363.2017.1410520 |
0.336 |
|
2017 |
Daniel M, Tollefsbol TO. Pterostilbene down-regulates hTERT at physiological concentrations in breast cancer cells: potentially through the inhibition of cMyc. Journal of Cellular Biochemistry. PMID 29125889 DOI: 10.1002/Jcb.26495 |
0.469 |
|
2017 |
Li Y, Meeran SM, Tollefsbol TO. Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression. Scientific Reports. 7: 9345. PMID 28839265 DOI: 10.1038/S41598-017-09764-3 |
0.443 |
|
2017 |
Lewis KA, Tollefsbol TO. The influence of an epigenetics diet on the cancer epigenome. Epigenomics. PMID 28799802 DOI: 10.2217/Epi-2017-0077 |
0.389 |
|
2017 |
Royston KJ, Udayakumar N, Lewis K, Tollefsbol TO. A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells. International Journal of Molecular Sciences. 18. PMID 28534825 DOI: 10.3390/Ijms18051092 |
0.506 |
|
2017 |
Dates CR, Tollefsbol TO. Transforming Cancer Epigenetics Using Nutritive Approaches and Non-coding RNAs. Current Cancer Drug Targets. PMID 28176654 DOI: 10.2174/1568009617666170203165326 |
0.434 |
|
2017 |
Martin SL, Kala R, Tollefsbol TO. Mechanisms for inhibition of colon cancer cells by sulforaphane through epigenetic modulation of microRNA-21 and human telomerase reverse transcriptase (hTERT) down-regulation. Current Cancer Drug Targets. PMID 28176652 DOI: 10.2174/1568009617666170206104032 |
0.507 |
|
2016 |
Li Y, Tollefsbol TO. Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases. Epigenomics. PMID 27882781 DOI: 10.2217/Epi-2016-0078 |
0.41 |
|
2016 |
Li Y, Buckhaults P, Cui X, Tollefsbol TO. Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals. Epigenomics. PMID 27478970 DOI: 10.2217/Epi-2016-0024 |
0.446 |
|
2016 |
Peek GW, Tollefsbol TO. Erratum to "Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 cancer cells with PX-866 and Raloxifene" [Exp. Cell Res. 344 (2016) 95-102]. Experimental Cell Research. PMID 27265745 DOI: 10.1016/J.Yexcr.2016.05.021 |
0.396 |
|
2016 |
Lewis KA, Tollefsbol TO. Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms. Frontiers in Genetics. 7: 83. PMID 27242892 DOI: 10.3389/Fgene.2016.00083 |
0.512 |
|
2016 |
Kala R, Tollefsbol TO. A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells. Plos One. 11: e0155057. PMID 27159275 DOI: 10.1371/Journal.Pone.0155057 |
0.483 |
|
2016 |
Peek GW, Tollefsbol TO. Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene. Experimental Cell Research. 344: 95-102. PMID 27017931 DOI: 10.1016/J.Yexcr.2016.03.022 |
0.441 |
|
2016 |
Saldanha SN, Royston KJ, Udayakumar N, Tollefsbol TO. Epigenetic Regulation of Epidermal Stem Cell Biomarkers and Their Role in Wound Healing. International Journal of Molecular Sciences. 17. PMID 26712738 DOI: 10.3390/Ijms17010016 |
0.79 |
|
2016 |
Peek GW, Tollefsbol TO. Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells. Journal of Cellular Biochemistry. 117: 1688-96. PMID 26660119 DOI: 10.1002/Jcb.25462 |
0.451 |
|
2015 |
Paul B, Barnes S, Demark-Wahnefried W, Morrow C, Salvador C, Skibola C, Tollefsbol TO. Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases. Clinical Epigenetics. 7: 112. PMID 26478753 DOI: 10.1186/S13148-015-0144-7 |
0.434 |
|
2015 |
Kala R, Shah HN, Martin SL, Tollefsbol TO. Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer. Bmc Cancer. 15: 672. PMID 26459286 DOI: 10.1186/S12885-015-1693-Z |
0.489 |
|
2015 |
Krakowsky RH, Tollefsbol TO. Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer. Frontiers in Nutrition. 2: 16. PMID 26075205 DOI: 10.3389/Fnut.2015.00016 |
0.385 |
|
2015 |
Gao Y, Tollefsbol TO. Impact of Epigenetic Dietary Components on Cancer through Histone Modifications. Current Medicinal Chemistry. 22: 2051-64. PMID 25891109 DOI: 10.2174/0929867322666150420102641 |
0.465 |
|
2015 |
Royston KJ, Tollefsbol TO. The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention. Current Pharmacology Reports. 1: 46-51. PMID 25774338 DOI: 10.1007/S40495-014-0003-9 |
0.46 |
|
2015 |
Sinha S, Shukla S, Khan S, Tollefsbol TO, Meeran SM. Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERα-dependent in ERα-negative human breast cancer cells. Molecular and Cellular Endocrinology. 406: 102-14. PMID 25725373 DOI: 10.1016/J.Mce.2015.02.020 |
0.473 |
|
2015 |
Daniel M, Tollefsbol TO. Epigenetic linkage of aging, cancer and nutrition. The Journal of Experimental Biology. 218: 59-70. PMID 25568452 DOI: 10.1242/Jeb.107110 |
0.461 |
|
2015 |
Tollefsbol T, Li Y. Abstract CN12-03: Epigenetic targets of sulforaphane and epigallocatechin gallate in cancer prevention Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-Cn12-03 |
0.473 |
|
2014 |
Saldanha SN, Kala R, Tollefsbol TO. Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. Experimental Cell Research. 324: 40-53. PMID 24518414 DOI: 10.1016/J.Yexcr.2014.01.024 |
0.823 |
|
2014 |
Tollefsbol TO. Dietary epigenetics in cancer and aging. Cancer Treatment and Research. 159: 257-67. PMID 24114485 DOI: 10.1007/978-3-642-38007-5_15 |
0.465 |
|
2014 |
Li Y, Saldanha SN, Tollefsbol TO. Impact of epigenetic dietary compounds on transgenerational prevention of human diseases. The Aaps Journal. 16: 27-36. PMID 24114450 DOI: 10.1208/S12248-013-9538-7 |
0.801 |
|
2014 |
Saldanha SN, Tollefsbol TO. Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis. Journal of Cellular Physiology. 229: 393-406. PMID 24105793 DOI: 10.1002/Jcp.24466 |
0.813 |
|
2013 |
Li Y, Tollefsbol TO. Analysis of biomarkers of caloric restriction in aging cells. Methods in Molecular Biology (Clifton, N.J.). 1048: 19-29. PMID 23929095 DOI: 10.1007/978-1-62703-556-9_3 |
0.348 |
|
2013 |
Chen H, Li Y, Tollefsbol TO. Cell senescence culturing methods. Methods in Molecular Biology (Clifton, N.J.). 1048: 1-10. PMID 23929093 DOI: 10.1007/978-1-62703-556-9_1 |
0.656 |
|
2013 |
Martin SL, Hardy TM, Tollefsbol TO. Medicinal chemistry of the epigenetic diet and caloric restriction Current Medicinal Chemistry. 20: 4050-4059. PMID 23895687 DOI: 10.2174/09298673113209990189 |
0.421 |
|
2013 |
Mitchell NE, Wilson ML, Bray MS, Crossman DK, Tollefsbol TO. Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis. Epigenomics. 5: 155-65. PMID 23566093 DOI: 10.2217/Epi.13.6 |
0.402 |
|
2013 |
Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO. Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane. Journal of Oncology. 2013: 872957. PMID 23476648 DOI: 10.1155/2013/872957 |
0.682 |
|
2013 |
Li Y, Meeran SM, Patel SN, Chen H, Hardy TM, Tollefsbol TO. Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. Molecular Cancer. 12: 9. PMID 23379261 DOI: 10.1186/1476-4598-12-9 |
0.655 |
|
2013 |
Li Y, Chen H, Hardy TM, Tollefsbol TO. Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein. Plos One. 8: e54369. PMID 23342141 DOI: 10.1371/Journal.Pone.0054369 |
0.689 |
|
2013 |
Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO. Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation. Experimental Cell Research. 319: 697-706. PMID 23333498 DOI: 10.1016/J.Yexcr.2012.12.026 |
0.704 |
|
2013 |
Shukla S, Khan S, Tollefsbol T, Meeran S. Genetics and Epigenetics of Lung Cancer: Mechanisms and Future Perspectives Current Cancer Therapy Reviews. 9: 97-110. DOI: 10.2174/15733947113099990002 |
0.428 |
|
2012 |
Meeran SM, Patel SN, Li Y, Shukla S, Tollefsbol TO. Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications. Plos One. 7: e37748. PMID 22662208 DOI: 10.1371/Journal.Pone.0037748 |
0.473 |
|
2012 |
Minocherhomji S, Tollefsbol TO, Singh KK. Mitochondrial regulation of epigenetics and its role in human diseases. Epigenetics. 7: 326-34. PMID 22419065 DOI: 10.4161/Epi.19547 |
0.318 |
|
2012 |
Daniel M, Peek GW, Tollefsbol TO. Regulation of the human catalytic subunit of telomerase (hTERT). Gene. 498: 135-46. PMID 22381618 DOI: 10.1016/J.Gene.2012.01.095 |
0.474 |
|
2012 |
Saldanha SN, Tollefsbol TO. The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. Journal of Oncology. 2012: 192464. PMID 22187555 DOI: 10.1155/2012/192464 |
0.789 |
|
2012 |
Kala R, Tollefsbol TO, Li Y. Potential of Resveratrol in Inhibiting Cancer and Slowing Aging Journal of Nutrition and Food Sciences. 2015: 1-9. DOI: 10.4172/2155-9600.S5-001 |
0.428 |
|
2012 |
Chen H, Landen CN, Alvarez RD, Li Y, Tollefsbol TO. Abstract 783: Combination treatment with epigallocatechin-3-gallate and sulforaphane sensitize ovarian cancer cells to cisplatin Cancer Research. 72: 783-783. DOI: 10.1158/1538-7445.Am2012-783 |
0.681 |
|
2012 |
Li Y, Tollefsbol T. Abstract 4029: Enhanced chemosensitivity of estrogen receptor-α (ERα)-negative breast cancer through soybean genistein-induced epigenetic reactivation of ERα Cancer Research. 72: 4029-4029. DOI: 10.1158/1538-7445.Am2012-4029 |
0.429 |
|
2011 |
Liu L, van Groen T, Kadish I, Li Y, Wang D, James SR, Karpf AR, Tollefsbol TO. Insufficient DNA methylation affects healthy aging and promotes age-related health problems. Clinical Epigenetics. 2: 349-60. PMID 22704347 DOI: 10.1007/S13148-011-0042-6 |
0.398 |
|
2011 |
Peek GW, Tollefsbol TO. The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention. Clinical Epigenetics. 2: 97-112. PMID 22704332 DOI: 10.1007/S13148-011-0020-Z |
0.398 |
|
2011 |
Chen H, Hardy TM, Tollefsbol TO. Epigenomics of ovarian cancer and its chemoprevention. Frontiers in Genetics. 2: 67. PMID 22303362 DOI: 10.3389/Fgene.2011.00067 |
0.693 |
|
2011 |
Hardy TM, Tollefsbol TO. Epigenetic diet: impact on the epigenome and cancer. Epigenomics. 3: 503-18. PMID 22022340 DOI: 10.2217/Epi.11.71 |
0.419 |
|
2011 |
Li Y, Tollefsbol TO. Combined chromatin immunoprecipitation and bisulfite methylation sequencing analysis. Methods in Molecular Biology (Clifton, N.J.). 791: 239-51. PMID 21913084 DOI: 10.1007/978-1-61779-316-5_18 |
0.427 |
|
2011 |
Mitchell N, Deangelis JT, Tollefsbol TO. Methylated-CpG Island Recovery Assay. Methods in Molecular Biology (Clifton, N.J.). 791: 125-33. PMID 21913076 DOI: 10.1007/978-1-61779-316-5_10 |
0.788 |
|
2011 |
Li Y, Tollefsbol TO. DNA methylation detection: bisulfite genomic sequencing analysis. Methods in Molecular Biology (Clifton, N.J.). 791: 11-21. PMID 21913068 DOI: 10.1007/978-1-61779-316-5_2 |
0.385 |
|
2011 |
Tollefsbol TO. Advances in epigenetic technology. Methods in Molecular Biology (Clifton, N.J.). 791: 1-10. PMID 21913067 DOI: 10.1007/978-1-61779-316-5_1 |
0.392 |
|
2011 |
Li Y, Daniel M, Tollefsbol TO. Epigenetic regulation of caloric restriction in aging. Bmc Medicine. 9: 98. PMID 21867551 DOI: 10.1186/1741-7015-9-98 |
0.428 |
|
2011 |
Meeran SM, Patel SN, Chan TH, Tollefsbol TO. A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 1243-54. PMID 21411498 DOI: 10.1158/1940-6207.Capr-11-0009 |
0.515 |
|
2011 |
Li Y, Tollefsbol TO. p16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms. Plos One. 6: e17421. PMID 21390332 DOI: 10.1371/Journal.Pone.0017421 |
0.41 |
|
2011 |
Nandakumar V, Vaid M, Tollefsbol TO, Katiyar SK. Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice. Carcinogenesis. 32: 597-604. PMID 21186298 DOI: 10.1093/Carcin/Bgq282 |
0.343 |
|
2011 |
DeAngelis JT, Li Y, Mitchell N, Wilson L, Kim H, Tollefsbol TO. 2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells. Journal of Proteome Research. 10: 447-58. PMID 21105747 DOI: 10.1021/Pr100533K |
0.793 |
|
2011 |
Sanders YY, Tollefsbol TO, Varisco BM, Hagood JS. Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 45: 16-23. PMID 20724553 DOI: 10.1165/Rcmb.2010-0154Oc |
0.428 |
|
2011 |
Hardy TM, Tollefsbol TO. Abstract B33: Differential responses of Caucasian and African American breast cancer cell lines after EGCG and sulforaphane treatment Cancer Epidemiology, Biomarkers & Prevention. 20. DOI: 10.1158/1055-9965.Disp-11-B33 |
0.367 |
|
2010 |
Meeran SM, Ahmed A, Tollefsbol TO. Epigenetic targets of bioactive dietary components for cancer prevention and therapy. Clinical Epigenetics. 1: 101-116. PMID 21258631 DOI: 10.1007/S13148-010-0011-5 |
0.494 |
|
2010 |
Li Y, Yuan YY, Meeran SM, Tollefsbol TO. Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells. Molecular Cancer. 9: 274. PMID 20946668 DOI: 10.1186/1476-4598-9-274 |
0.433 |
|
2010 |
Meeran SM, Patel SN, Tollefsbol TO. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. Plos One. 5: e11457. PMID 20625516 DOI: 10.1371/Journal.Pone.0011457 |
0.468 |
|
2010 |
Li Y, Tollefsbol TO. Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Current Medicinal Chemistry. 17: 2141-51. PMID 20423306 DOI: 10.2174/092986710791299966 |
0.487 |
|
2010 |
Queen BL, Tollefsbol TO. Polyphenols and aging. Current Aging Science. 3: 34-42. PMID 20298168 DOI: 10.2174/1874609811003010034 |
0.386 |
|
2010 |
Li Y, Liu L, Tollefsbol TO. Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1442-53. PMID 20019239 DOI: 10.1096/Fj.09-149328 |
0.43 |
|
2010 |
Meeran SM, Li Y, Ahmed A, Tollefsbol TO. Abstract 4878: Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by epigenetic mechanisms involving active chromatin modification Cancer Research. 70: 4878-4878. DOI: 10.1158/1538-7445.Am10-4878 |
0.441 |
|
2010 |
Meeran SM, Patel SN, Chan T, Tollefsbol TO. Abstract 3206: A novel prodrug of the green tea polyphenol (−)-epigallocatechin-3-gallate inhibits the telomerase gene by modifying DNA methylation and histone acetylation in breast cancer cells Cancer Research. 70: 3206-3206. DOI: 10.1158/1538-7445.Am10-3206 |
0.524 |
|
2009 |
Phipps SM, Love WK, White T, Andrews LG, Tollefsbol TO. Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells. Anticancer Research. 29: 4959-64. PMID 20044602 |
0.821 |
|
2009 |
Li Y, Liu L, Andrews LG, Tollefsbol TO. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. International Journal of Cancer. 125: 286-96. PMID 19358274 DOI: 10.1002/Ijc.24398 |
0.532 |
|
2009 |
Chen H, Li Y, Tollefsbol TO. Strategies targeting telomerase inhibition. Molecular Biotechnology. 41: 194-9. PMID 18956258 DOI: 10.1007/S12033-008-9117-9 |
0.692 |
|
2009 |
Phipps SM, Love WK, Mott TE, Andrews LG, Tollefsbol TO. Differential expression of epigenetic modulators during human embryonic stem cell differentiation. Molecular Biotechnology. 41: 201-7. PMID 18953677 DOI: 10.1007/S12033-008-9118-8 |
0.814 |
|
2009 |
Liu L, van Groen T, Kadish I, Tollefsbol TO. DNA methylation impacts on learning and memory in aging. Neurobiology of Aging. 30: 549-60. PMID 17850924 DOI: 10.1016/J.Neurobiolaging.2007.07.020 |
0.356 |
|
2008 |
Love WK, Deangelis JT, Berletch JB, Phipps SM, Andrews LG, Brouillette WJ, Muccio DD, Tollefsbol TO. The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells. Translational Oncology. 1: 148-52. PMID 18795149 DOI: 10.1593/Tlo.08142 |
0.779 |
|
2008 |
Punathil T, Tollefsbol TO, Katiyar SK. EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase. Biochemical and Biophysical Research Communications. 375: 162-7. PMID 18692479 DOI: 10.1016/J.Bbrc.2008.07.157 |
0.419 |
|
2008 |
Sanders YY, Pardo A, Selman M, Nuovo GJ, Tollefsbol TO, Siegal GP, Hagood JS. Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 39: 610-8. PMID 18556592 DOI: 10.1165/Rcmb.2007-0322Oc |
0.444 |
|
2008 |
Liu L, Li Y, Tollefsbol TO. Gene-environment interactions and epigenetic basis of human diseases. Current Issues in Molecular Biology. 10: 25-36. PMID 18525104 |
0.317 |
|
2008 |
Love WK, Berletch JB, Andrews LG, Tollefsbol TO. Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells. International Journal of Oncology. 32: 625-31. PMID 18292940 DOI: 10.3892/Ijo.32.3.625 |
0.805 |
|
2008 |
DeAngelis JT, Farrington WJ, Tollefsbol TO. An overview of epigenetic assays. Molecular Biotechnology. 38: 179-83. PMID 17943463 DOI: 10.1007/S12033-007-9010-Y |
0.804 |
|
2008 |
Berletch JB, Liu C, Love WK, Andrews LG, Katiyar SK, Tollefsbol TO. Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG. Journal of Cellular Biochemistry. 103: 509-19. PMID 17570133 DOI: 10.1002/Jcb.21417 |
0.809 |
|
2007 |
Cunningham AP, Andrews LG, Tollefsbol TO. Retrovirus-mediated RNA interference. Targeting hTERT through stable expression of short-hairpin RNA. Methods in Molecular Biology (Clifton, N.J.). 405: 39-46. PMID 18369816 DOI: 10.1007/978-1-60327-070-0_5 |
0.328 |
|
2007 |
Lai SR, Andrews LG, Tollefsbol TO. hTERT knockdown in human embryonic kidney cells using double-stranded RNA. Methods in Molecular Biology (Clifton, N.J.). 405: 23-9. PMID 18369814 DOI: 10.1007/978-1-60327-070-0_3 |
0.333 |
|
2007 |
Andrews LG, Tollefsbol TO. Methods of telomerase inhibition. Methods in Molecular Biology (Clifton, N.J.). 405: 1-7. PMID 18369812 DOI: 10.1007/978-1-60327-070-0_1 |
0.395 |
|
2007 |
Berletch JB, Phipps SM, Walthall SL, Andrews LG, Tollefsbol TO. A method to study the expression of DNA methyltransferases in aging systems in vitro. Methods in Molecular Biology (Clifton, N.J.). 371: 81-7. PMID 17634575 DOI: 10.1007/978-1-59745-361-5_7 |
0.787 |
|
2007 |
Berletch JB, Andrews LG, Tollefsbol TO. A method to detect DNA methyltransferase I gene transcription in vitro in aging systems. Methods in Molecular Biology (Clifton, N.J.). 371: 73-80. PMID 17634574 DOI: 10.1007/978-1-59745-361-5_6 |
0.777 |
|
2007 |
Phipps SM, Berletch JB, Andrews LG, Tollefsbol TO. Aging cell culture: methods and observations. Methods in Molecular Biology (Clifton, N.J.). 371: 9-19. PMID 17634570 DOI: 10.1007/978-1-59745-361-5_2 |
0.77 |
|
2007 |
Tollefsbol TO. Techniques for analysis of biological aging. Methods in Molecular Biology (Clifton, N.J.). 371: 1-7. PMID 17634569 DOI: 10.1007/978-1-59745-361-5_1 |
0.333 |
|
2007 |
Hansen NJ, Wylie RC, Phipps SM, Love WK, Andrews LG, Tollefsbol TO. The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells. International Journal of Oncology. 30: 641-50. PMID 17273765 DOI: 10.3892/Ijo.30.3.641 |
0.817 |
|
2007 |
Lai SR, Cunningham AP, Huynh VQ, Andrews LG, Tollefsbol TO. Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop. Experimental Cell Research. 313: 322-30. PMID 17134697 DOI: 10.1016/J.Yexcr.2006.10.014 |
0.437 |
|
2006 |
Cunningham AP, Love WK, Zhang RW, Andrews LG, Tollefsbol TO. Telomerase inhibition in cancer therapeutics: molecular-based approaches. Current Medicinal Chemistry. 13: 2875-88. PMID 17073634 DOI: 10.2174/092986706778521887 |
0.438 |
|
2006 |
Liu L, Andrews LG, Tollefsbol TO. Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death. Oncogene. 25: 4370-5. PMID 16501599 DOI: 10.1038/Sj.Onc.1209454 |
0.469 |
|
2005 |
Ulrey CL, Liu L, Andrews LG, Tollefsbol TO. The impact of metabolism on DNA methylation. Human Molecular Genetics. 14: R139-47. PMID 15809266 DOI: 10.1093/Hmg/Ddi100 |
0.386 |
|
2005 |
Lai SR, Phipps SM, Liu L, Andrews LG, Tollefsbol TO. Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1779-96. PMID 15769667 DOI: 10.2741/1661 |
0.82 |
|
2005 |
Phipps S, Woodfin W, Tollefsbol T. The Epigenetics of Breast Carcinogenesis and Metastasis Current Genomics. 6: 129-135. DOI: 10.2174/1389202053971956 |
0.318 |
|
2004 |
Liu L, Lai S, Andrews LG, Tollefsbol TO. Genetic and epigenetic modulation of telomerase activity in development and disease. Gene. 340: 1-10. PMID 15556289 DOI: 10.1016/J.Gene.2004.06.011 |
0.464 |
|
2004 |
Liu L, Berletch JB, Green JG, Pate MS, Andrews LG, Tollefsbol TO. Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation. Molecular Cancer Therapeutics. 3: 1003-9. PMID 15299083 |
0.771 |
|
2004 |
Liu L, Wylie RC, Hansen NJ, Andrews LG, Tollefsbol TO. Profiling DNA methylation by bisulfite genomic sequencing: problems and solutions. Methods in Molecular Biology (Clifton, N.J.). 287: 169-79. PMID 15273411 DOI: 10.1385/1-59259-828-5:169 |
0.308 |
|
2004 |
Tollefsbol TO. Methods of epigenetic analysis. Methods in Molecular Biology (Clifton, N.J.). 287: 1-8. PMID 15273399 DOI: 10.1385/1-59259-828-5:001 |
0.403 |
|
2004 |
Liu L, Saldanha SN, Pate MS, Andrews LG, Tollefsbol TO. Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation. Genes, Chromosomes & Cancer. 41: 26-37. PMID 15236314 DOI: 10.1002/Gcc.20058 |
0.828 |
|
2004 |
Mittal A, Pate MS, Wylie RC, Tollefsbol TO, Katiyar SK. EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis. International Journal of Oncology. 24: 703-10. PMID 14767556 DOI: 10.3892/Ijo.24.3.703 |
0.469 |
|
2004 |
Berletch J, Green J, Cunningham A, Andrews L, Tollefsbol T. Novel Approaches for RNA Interference and their Application in Cancer Therapy Current Pharmacogenomics. 2: 313-324. DOI: 10.2174/1570160043377321 |
0.714 |
|
2003 |
Ahmed A, Tollefsbol TO. Telomerase, telomerase inhibition, and cancer. Journal of Anti-Aging Medicine. 6: 315-25. PMID 15142433 DOI: 10.1089/109454503323028911 |
0.479 |
|
2003 |
Liu L, Wylie RC, Andrews LG, Tollefsbol TO. Aging, cancer and nutrition: the DNA methylation connection. Mechanisms of Ageing and Development. 124: 989-98. PMID 14659588 DOI: 10.1016/J.Mad.2003.08.001 |
0.473 |
|
2003 |
Casillas MA, Lopatina N, Andrews LG, Tollefsbol TO. Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Molecular and Cellular Biochemistry. 252: 33-43. PMID 14577574 DOI: 10.1023/A:1025548623524 |
0.513 |
|
2003 |
Casillas MA, Brotherton SL, Andrews LG, Ruppert JM, Tollefsbol TO. Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements. Gene. 316: 57-65. PMID 14563552 DOI: 10.1016/S0378-1119(03)00739-X |
0.405 |
|
2003 |
Lopatina NG, Poole JC, Saldanha SN, Hansen NJ, Key JS, Pita MA, Andrews LG, Tollefsbol TO. Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. Biochemical and Biophysical Research Communications. 306: 650-9. PMID 12810068 DOI: 10.1016/S0006-291X(03)01033-7 |
0.836 |
|
2003 |
Saldanha SN, Andrews LG, Tollefsbol TO. Analysis of telomerase activity and detection of its catalytic subunit, hTERT. Analytical Biochemistry. 315: 1-21. PMID 12672407 DOI: 10.1016/S0003-2697(02)00663-2 |
0.78 |
|
2003 |
Saldanha SN, Andrews LG, Tollefsbol TO. Assessment of telomere length and factors that contribute to its stability. European Journal of Biochemistry / Febs. 270: 389-403. PMID 12542689 DOI: 10.1046/J.1432-1033.2003.03410.X |
0.768 |
|
2003 |
Ahmed A, Tollefsbol T. Telomeres, telomerase, and telomerase inhibition: clinical implications for cancer. Journal of the American Geriatrics Society. 51: 116-22. PMID 12534855 DOI: 10.1034/J.1601-5215.2002.51019.X |
0.457 |
|
2002 |
Lopatina N, Haskell JF, Andrews LG, Poole JC, Saldanha S, Tollefsbol T. Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts. Journal of Cellular Biochemistry. 84: 324-34. PMID 11787061 DOI: 10.1002/Jcb.10015 |
0.818 |
|
2001 |
Ahmed A, Tollefsbol T. Telomeres and telomerase: basic science implications for aging. Journal of the American Geriatrics Society. 49: 1105-9. PMID 11555075 DOI: 10.1046/J.1532-5415.2001.49217.X |
0.399 |
|
2001 |
Tollefsbol TO, Andrews LG. Mechanisms for telomerase gene control in aging cells and tumorigenesis. Medical Hypotheses. 56: 630-7. PMID 11399111 DOI: 10.1054/Mehy.2000.1241 |
0.502 |
|
2001 |
Poole JC, Andrews LG, Tollefsbol TO. Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT). Gene. 269: 1-12. PMID 11376932 DOI: 10.1016/S0378-1119(01)00440-1 |
0.42 |
|
1998 |
Tollefsbol TO, Hutchison CA. Analysis in Escherichia coli of the effects of in vivo CpG methylation catalyzed by the cloned murine maintenance methyltransferase. Biochemical and Biophysical Research Communications. 245: 670-8. PMID 9588173 DOI: 10.1006/Bbrc.1998.8422 |
0.45 |
|
1997 |
Tollefsbol TO, Hutchison CA. Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase. Journal of Molecular Biology. 269: 494-504. PMID 9217255 DOI: 10.1006/Jmbi.1997.1064 |
0.365 |
|
1995 |
Tollefsbol TO, Hutchison CA. Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized. The Journal of Biological Chemistry. 270: 18543-50. PMID 7629184 DOI: 10.1074/Jbc.270.31.18543 |
0.379 |
|
1993 |
Tollefsbol TO, Andrews LG. Mechanisms for methylation-mediated gene silencing and aging. Medical Hypotheses. 41: 83-92. PMID 8231986 DOI: 10.1016/0306-9877(93)90040-W |
0.412 |
|
1991 |
Tollefsbol TO, Cohen HJ. The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. Biochemical Medicine and Metabolic Biology. 44: 282-91. PMID 2149643 DOI: 10.1016/0885-4505(90)90073-A |
0.333 |
|
1987 |
Tollefsbol TO, Cohen HJ. Expression of intracellular biochemical defects of lymphocytes in aging: proposal of a general aging mechanism which is not cell-specific. Experimental Gerontology. 21: 129-48. PMID 3542542 DOI: 10.1016/0531-5565(86)90067-7 |
0.369 |
|
1985 |
Gracy RW, Chapman ML, Cini JK, Jahani M, Tollefsbol TO, Yüksel KU. Molecular basis of the accumulation of abnormal proteins in progeria and aging fibroblasts Basic Life Sciences. 35: 427-442. PMID 4062822 DOI: 10.1007/978-1-4899-2218-2_27 |
0.306 |
|
1985 |
Tollefsbol TO, Cohen HJ. Decreased protein synthesis of transforming lymphocytes from aged humans: relationship to impaired mitogenesis with age. Mechanisms of Ageing and Development. 30: 53-62. PMID 3999813 DOI: 10.1016/0047-6374(85)90058-2 |
0.347 |
|
1985 |
Tollefsbol TO, Cohen HJ. Carbohydrate metabolism in transforming lymphocytes from the aged. Journal of Cellular Physiology. 123: 417-24. PMID 3988814 DOI: 10.1002/Jcp.1041230318 |
0.31 |
|
1985 |
Tollefsbol TO, Cohen HJ. Culture kinetics of glycolytic enzyme induction, glucose utilization, and thymidine incorporation of extended-exposure phytohemagglutinin-stimulated human lymphocytes. Journal of Cellular Physiology. 122: 98-104. PMID 3965487 DOI: 10.1002/Jcp.1041220115 |
0.322 |
|
1984 |
Tollefsbol TO, Cohen HJ. The effect of age on the accumulation of labile triosephosphate isomerase and thymidine incorporation in pokeweed mitogen stimulated human lymphocytes. Journal of Gerontology. 39: 398-405. PMID 6736575 DOI: 10.1093/Geronj/39.4.398 |
0.319 |
|
1982 |
Tollefsbol TO, Zaun MR, Gracy RW. Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts Mechanisms of Ageing and Development. 20: 93-101. PMID 7176709 DOI: 10.1016/0047-6374(82)90061-6 |
0.311 |
|
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