Benjamin Ebert - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Cell Biology, Oncology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Uddin MM, Saadatagah S, Niroula A, Yu B, Hornsby WE, Ganesh S, Lannery K, Schuermans A, Honigberg MC, Bick AG, Libby P, Ebert BL, Ballantyne CM, Natarajan P. Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis. Nature Communications. 15: 7858. PMID 39251642 DOI: 10.1038/s41467-024-52302-9  0.302
2023 Rauch PJ, Gopakumar J, Silver AJ, Nachun D, Ahmad H, McConkey M, Nakao T, Bosse M, Rentz T, Vivanco Gonzalez N, Greenwald NF, McCaffrey EF, Khair Z, Gopakumar M, Rodrigues KB, ... ... Ebert BL, et al. Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes. Nature Cardiovascular Research. 2: 805-818. PMID 39196062 DOI: 10.1038/s44161-023-00326-7  0.301
2023 Schuermans A, Vlasschaert C, Nauffal V, Cho SMJ, Uddin MM, Nakao T, Niroula A, Klarqvist MDR, Weeks LD, Lin AE, Saadatagah S, Lannery K, Wong M, Hornsby W, Lubitz SA, ... ... Ebert BL, et al. Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias. European Heart Journal. PMID 37952204 DOI: 10.1093/eurheartj/ehad670  0.637
2023 Ahmad MH, Hegde M, Wong WJ, M Hosseini M, Garrett LJ, Carrascoso A, Issac N, Ebert BL, Silva JC, Pihan G, Zhu LJ, Wolfe S, Agarwal A, Liu PP, Castilla LH. Runx1-R188Q germline mutation induces inflammation and predisposition to hematologic malignancies in mice. Blood Advances. PMID 37756546 DOI: 10.1182/bloodadvances.2023010398  0.304
2023 Yu Z, Filder TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, ... ... Ebert BL, et al. Genetic modification of inflammation and clonal hematopoiesis-associated cardiovascular risk. The Journal of Clinical Investigation. PMID 37498674 DOI: 10.1172/JCI168597  0.649
2023 Weeks LD, Niroula A, Neuberg D, Wong W, Lindsley RC, Luskin M, Berliner N, Stone RM, DeAngelo DJ, Soiffer R, Uddin MM, Griffin G, Vlasschaert C, Gibson CJ, Jaiswal S, ... ... Ebert BL, et al. Prediction of risk for myeloid malignancy in clonal hematopoiesis. Nejm Evidence. 2. PMID 37483562 DOI: 10.1056/evidoa2200310  0.652
2023 Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, ... ... Ebert BL, et al. Author Correction: Clonal haematopoiesis and risk of chronic liver disease. Nature. PMID 37400552 DOI: 10.1038/s41586-023-06375-z  0.586
2023 Marion W, Koppe T, Chen CC, Wang D, Frenis K, Fierstein S, Sensharma P, Aumais O, Peters M, Ruiz-Torres S, Chihanga T, Boettcher S, Shimamura A, Bauer DE, Schlaeger T, ... ... Ebert BL, et al. RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia. Leukemia. PMID 37391485 DOI: 10.1038/s41375-023-01945-6  0.307
2023 Schuermans A, Nakao T, Ruan Y, Koyama S, Yu Z, Uddin MM, Haidermota S, Hornsby W, Lewandowski AJ, Bick AG, Niroula A, Jaiswal S, Ebert BL, Natarajan P, Honigberg MC. Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood. Journal of the American Heart Association. e030220. PMID 37345823 DOI: 10.1161/JAHA.123.030220  0.619
2023 Gumuser ED, Schuermans A, Cho SMJ, Sporn ZA, Uddin MM, Paruchuri K, Nakao T, Yu Z, Haidermota S, Hornsby W, Weeks LD, Niroula A, Jaiswal S, Libby P, Ebert BL, et al. Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease. Journal of the American College of Cardiology. 81: 1996-2009. PMID 37197843 DOI: 10.1016/j.jacc.2023.03.401  0.665
2023 Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, ... ... Ebert BL, et al. Clonal haematopoiesis and risk of chronic liver disease. Nature. PMID 37046084 DOI: 10.1038/s41586-023-05857-4  0.598
2023 Vlasschaert C, Mack T, Heimlich JB, Niroula A, Uddin MM, Weinstock JS, Sharber B, Silver AJ, Xu Y, Savona MR, Gibson CJ, Lanktree MB, Rauh MJ, Ebert BL, Natarajan P, et al. A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets. Blood. PMID 36652671 DOI: 10.1182/blood.2022018825  0.639
2022 Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, ... ... Ebert BL, et al. Genomic Profiling for Clinical Decision Making in Myeloid Neoplasms and Acute Leukemia. Blood. PMID 36130297 DOI: 10.1182/blood.2022015853  0.632
2022 Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, ... ... Ebert BL, et al. Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Nature Communications. 13: 5350. PMID 36097025 DOI: 10.1038/s41467-022-33093-3  0.664
2022 Miller PG, Sathappa M, Moroco JA, Jiang W, Qian Y, Iqbal S, Guo Q, Giacomelli AO, Shaw S, Vernier C, Bajrami B, Yang X, Raffier C, Sperling AS, Gibson CJ, ... ... Ebert BL, et al. Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state. Nature Communications. 13: 3778. PMID 35773251 DOI: 10.1038/s41467-022-30463-9  0.7
2022 Agrawal M, Niroula A, Cunin P, McConkey M, Kovalcik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, ... ... Ebert BL, et al. TET2-mutant clonal hematopoiesis and risk of gout. Blood. PMID 35714308 DOI: 10.1182/blood.2022015384  0.614
2022 Nakao T, Bick AG, Taub MA, Zekavat SM, Uddin MM, Niroula A, Carty CL, Lane J, Honigberg MC, Weinstock JS, Pampana A, Gibson CJ, Griffin GK, Clarke SL, Bhattacharya R, ... ... Ebert BL, et al. Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential. Science Advances. 8: eabl6579. PMID 35385311 DOI: 10.1126/sciadv.abl6579  0.635
2021 Miller P, Qiao D, Rojas-Quintero J, Honigberg MC, Sperling AS, Gibson CJ, Bick AG, Niroula A, McConkey ME, Sandoval B, Miller B, Shi W, Viswanathan K, Leventhal MJ, Werner L, ... ... Ebert BL, et al. Association of Clonal Hematopoiesis with Chronic Obstructive Pulmonary Disease. Blood. PMID 34855941 DOI: 10.1182/blood.2021013531  0.633
2021 Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MM, Bick AG, Niroula A, Yu B, Gibson C, Griffin G, Morrison AC, Psaty BM, Longstreth WT, Bis JC, ... ... Ebert BL, et al. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke. Stroke. STROKEAHA121037388. PMID 34743536 DOI: 10.1161/STROKEAHA.121.037388  0.582
2021 Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Słabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, ... ... Ebert BL, et al. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. The Journal of Experimental Medicine. 218. PMID 34698806 DOI: 10.1084/jem.20211872  0.64
2021 Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, Bick AG, Uddin MM, Gibson CJ, Griffin GK, Honigberg MC, Zekavat SM, Paruchuri K, Natarajan P, Ebert BL. Distinction of lymphoid and myeloid clonal hematopoiesis. Nature Medicine. PMID 34663986 DOI: 10.1038/s41591-021-01521-4  0.311
2021 Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, ... ... Ebert BL, et al. is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discovery. 2: 500-517. PMID 34568833 DOI: 10.1158/2643-3230.BCD-20-0224  0.661
2021 Huang YH, Chen CW, Sundaramurthy V, Slabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, ... ... Ebert BL, et al. Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor. Cancer Discovery. PMID 34429321 DOI: 10.1158/2159-8290.CD-21-0560  0.305
2021 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, ... ... Ebert BL, et al. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33707633 DOI: 10.1038/s41586-021-03280-1  0.573
2021 Iacobucci I, Qu C, Varotto E, Janke LJ, Yang X, Seth A, Shelat A, Friske J, Fukano R, Yu J, Freeman BB, Kennedy JA, Sperling AS, Zheng R, Wang Y, ... ... Ebert BL, et al. Modeling and targeting of erythroleukemia by hematopoietic genome editing. Blood. PMID 33512458 DOI: 10.1182/blood.2020009103  0.312
2020 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, ... ... Ebert BL, et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33057201 DOI: 10.1038/s41586-020-2819-2  0.682
2020 Sidlow R, Lin AE, Gupta D, Bolton KL, Steensma DP, Levine RL, Ebert BL, Libby P. The Clinical Challenge of Clonal Hematopoiesis, a Newly Recognized Cardiovascular Risk Factor. Jama Cardiology. PMID 32459358 DOI: 10.1001/jamacardio.2020.1271  0.309
2019 Steensma DP, Ebert BL. Clonal hematopoiesis as a model for premalignant changes during aging. Experimental Hematology. PMID 31838005 DOI: 10.1016/j.exphem.2019.12.001  0.326
2019 Jaiswal S, Ebert BL. Clonal hematopoiesis in human aging and disease. Science (New York, N.Y.). 366. PMID 31672865 DOI: 10.1126/Science.Aan4673  0.659
2019 Libby P, Sidlow R, Lin AE, Gupta D, Jones LW, Moslehi J, Zeiher A, Jaiswal S, Schulz C, Blankstein R, Bolton KL, Steensma D, Levine RL, Ebert BL. Clonal Hematopoiesis: Crossroads of Aging, Cardiovascular Disease, and Cancer: JACC Review Topic of the Week. Journal of the American College of Cardiology. 74: 567-577. PMID 31345432 DOI: 10.1016/J.Jacc.2019.06.007  0.642
2019 Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, ... ... Ebert BL, et al. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nature Genetics. 51: 694-704. PMID 30926971 DOI: 10.1038/S41588-019-0375-1  0.305
2019 De Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, Matthews G, Yiguo H, Sheffer M, Dhimolea E, Dashevsky O, Gandolfi S, Dempster J, Meyers RM, Bryan J, McFarland JM, Brueggenthies J, Tang H, ... ... Ebert B, et al. Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma Blood. 134: 4407-4407. DOI: 10.1182/Blood-2019-130901  0.347
2019 Vallurupalli M, Gorelov R, Garcia JS, Morgan EA, Ebert B, Tothova Z. Talazoparib Treatment Preferentially Depletes Cohesin-Mutant Clones in New In Vivo Models of Cohesin-Mutant Myeloid Diseases Blood. 134: 560-560. DOI: 10.1182/Blood-2019-130308  0.386
2019 Goll JB, Lindsley RC, Hooper WF, Bejar R, Walker J, Fulton R, Abel GA, Al Baghdadi T, Deeg HJ, DeZern AE, Ebert B, Epling-Burnette P, Foran JM, Gorak EJ, Gore SD, et al. Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study Blood. 134: 4271-4271. DOI: 10.1182/Blood-2019-126978  0.368
2018 Libby P, Jaiswal S, Lin AE, Ebert BL. CHIPping Away at the Pathogenesis of Heart Failure. Jama Cardiology. PMID 30566187 DOI: 10.1001/Jamacardio.2018.4039  0.554
2018 Sellar RS, Jaiswal S, Ebert BL. Predicting progression to AML. Nature Medicine. 24: 904-906. PMID 29988142 DOI: 10.1038/S41591-018-0114-7  0.645
2018 Kahn JD, Miller PG, Silver AJ, Sellar RS, Bhatt S, Gibson C, McConkey M, Adams D, Mar B, Mertins P, Fereshetian S, Krug K, Zhu H, Letai A, Carr SA, ... ... Ebert BL, et al. PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells. Blood. PMID 29954749 DOI: 10.1182/Blood-2018-05-850339  0.658
2018 Iacobucci I, Varotto E, Qu C, Janke L, Seth A, Shelat A, Freeman B, Kennedy J, Sperling AS, Lindsley RC, Dickerson K, Payne-Turner D, Morris SM, Ghosn N, Ebert BL, et al. Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets Blood. 132: 5-5. DOI: 10.1182/Blood-2018-99-118817  0.33
2018 Rauch PJ, Silver AJ, Gopakumar J, McConkey M, Sinha E, Fefer M, Shvartz E, Sukhova G, Libby P, Ebert BL, Jaiswal S. Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice Blood. 132: 745-745. DOI: 10.1182/Blood-2018-99-118288  0.661
2018 Wang L, Yin S, Martinez Az, Regis FF, Brooks A, Herman SEM, Ten Hacken E, Obeng E, Campagna D, Fleming MD, Ebert BL, Wiestner A, Leshchiner I, Getz G, Carrasco RD, et al. Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling Blood. 132: 947-947. DOI: 10.1182/Blood-2018-99-117691  0.331
2018 Renella R, Gagne K, Beauchamp E, Schlaeger T, Hofmann I, Shimamura A, Fogel J, Agarwal S, Ebert BL, Markianos K, Springer TA, Fleming MD, Williams DA. Congenital X-Linked Myelodysplasia with Tetraploidy Is Associated with De Novo Germline C-Terminal Mutation of SEPT6, a Septin Filament Protein Blood. 132: 644-644. DOI: 10.1182/Blood-2018-99-114682  0.331
2017 Jaiswal S, Natarajan P, Ebert BL. Clonal Hematopoiesis and Atherosclerosis. The New England Journal of Medicine. 377: 1401-1402. PMID 28976867 DOI: 10.1056/Nejmc1710381  0.59
2017 Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, Baber U, Mehran R, Fuster V, Danesh J, Frossard P, ... ... Ebert BL, et al. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease. The New England Journal of Medicine. PMID 28636844 DOI: 10.1056/Nejmoa1701719  0.65
2017 Jan M, Ebert BL, Jaiswal S. Clonal hematopoiesis. Seminars in Hematology. 54: 43-50. PMID 28088988 DOI: 10.1053/j.seminhematol.2016.10.002  0.672
2017 Gibson CJ, Lindsley RC, Tchekmedyian V, Mar BG, Shi J, Jaiswal S, Bosworth A, Francisco L, He J, Bansal A, Morgan EA, Lacasce AS, Freedman AS, Fisher DC, Jacobsen E, ... ... Ebert BL, et al. Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016716712. PMID 28068180 DOI: 10.1200/Jco.2016.71.6712  0.649
2016 Li H, Mar BG, Zhang H, Puram RV, Vazquez F, Weir BA, Hahn WC, Ebert B, Pellman D. The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia. Blood. PMID 27756750 DOI: 10.1182/Blood-2016-05-714493  0.357
2016 Gibson CJ, Lindsley RC, Tchekmedyian V, Shi J, Mar BG, Jaiswal S, Bosworth A, Francisco LF, He J, Morgan EA, LaCasce AS, Koreth J, Ho VT, Ritz J, Nikiforow S, ... ... Ebert BL, et al. Clonal Hematopoiesis Associated with Adverse Outcomes Following Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma Blood. 128: 986-986. DOI: 10.1182/Blood.V128.22.986.986  0.658
2016 Wang L, Gambe R, Sun J, Shukla S, Kim J, Brooks AN, Neuberg DS, Fleming MD, Ebert BL, Carrasco RD, Wu CJ. Genome-Wide Analysis of a Novel Murine Model of Chronic Lymphocytic Leukemia Blood. 128: 967-967. DOI: 10.1182/Blood.V128.22.967.967  0.312
2016 Tothova Z, Krill-Burger JM, Popova KD, Sievers Q, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL. Generation of Models of Human Hematologic Malignancies Using CRISPR Genome Engineering Blood. 128: 741-741. DOI: 10.1182/Blood.V128.22.741.741  0.319
2016 Kahn J, Silver AJ, Mertins P, Carr S, Jaiswal S, Ebert BL. PPM1D Truncating Mutations Confer Chemotherapy Resistance in Hematopoietic Stem Cells, Which Is Reversible By PPM1D Inhibition Blood. 128: 740-740. DOI: 10.1182/Blood.V128.22.740.740  0.644
2016 Vu LP, Prieto C, Amin E, Minuesa G, Chhangawala S, Vidal MJ, Krivtsov AV, Chou T, Barlowe T, Taggart J, Tivnan P, Deering RP, Gonen M, Figueroa ME, Paietta E, ... ... Ebert B, et al. RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program Blood. 128: 739-739. DOI: 10.1182/Blood.V128.22.739.739  0.353
2016 McGraw K, Cheng C, Chen A, Genovese G, Cluzeau T, Lin H, Przychodzen B, Mallo M, Arenillas L, Mohamedali A, Ades L, Basiorka A, Irvine B, Sallman D, Padron E, ... ... Ebert B, et al. Abstract 2570: Identification of genetic polymorphisms associated with myelodysplastic syndromes by genome-wide association study Cancer Research. 76: 2570-2570. DOI: 10.1158/1538-7445.Am2016-2570  0.323
2016 Wang L, Brooks A, Gambe R, Fan J, Sun J, Hergert S, Wan Y, Neuberg D, Kharchenko P, Meyerson M, Fleming M, Ebert B, Wu C. From Human Genetic to Mouse Model: SF3B1 Mutation and its Impact on Chronic Lymphocytic Leukemia Clinical Lymphoma Myeloma and Leukemia. 16: S52. DOI: 10.1016/J.Clml.2016.07.076  0.338
2015 Steensma DP, Bejar R, Jaiswal S, Lindsley RC, Sekeres MA, Hasserjian RP, Ebert BL. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood. 126: 9-16. PMID 25931582 DOI: 10.1182/Blood-2015-03-631747  0.675
2015 Genovese G, Jaiswal S, Ebert BL, McCarroll SA. Clonal hematopoiesis and blood-cancer risk. The New England Journal of Medicine. 372: 1071-2. PMID 25760361 DOI: 10.1056/NEJMc1500684  0.599
2015 Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, ... ... Ebert BL, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nature Medicine. 21: 71-5. PMID 25485910 DOI: 10.1038/Nm.3751  0.633
2015 Ebert BL. Clonal Diversity and Mutated Genes in Myelodysplastic Syndromes Blood. 126: SCI-3-SCI-3. DOI: 10.1182/blood.v126.23.sci-3.sci-3  0.315
2015 Sigmans J, Noort W, Lindsley C, Pan L, Aalders L, Bariteau M, Ebert B, Aster J, Steidl U, Schuringa J, Yuan H, Bruijn Jd, Raymakers R, Lokhorst H, Mutis T, et al. Abstract PR12: Biological insights into tumor-bone marrow microenvironment interactions derived from a humanized murine model Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-Pr12  0.316
2015 Ebert B. Abstract SY13-03: Novel targeted therapies in myelodysplastic syndrome Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy13-03  0.307
2015 Buonamici S, Perino S, Lim K, Darman R, Feala J, Peng S, Bhavsar E, Corson L, Keaney G, Mizui Y, Obeng E, Park E, Wang J, Warmuth M, Yu L, ... ... Ebert B, et al. 21 SF3B1 MUTATIONS INDUCE ABERRANT SPLICING LEADING TO A BLOCK IN ERYTHROID DIFFERENTIATION AND COMPETITIVE ADVANTAGE Leukemia Research. 39: S9. DOI: 10.1016/S0145-2126(15)30022-9  0.304
2014 Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, ... ... Ebert BL, et al. Age-related clonal hematopoiesis associated with adverse outcomes. The New England Journal of Medicine. 371: 2488-98. PMID 25426837 DOI: 10.1056/Nejmoa1408617  0.645
2014 Jaiswal S, Ebert BL. MDS is a stem cell disorder after all Cancer Cell. 25: 713-714. PMID 24937455 DOI: 10.1016/J.Ccr.2014.06.001  0.622
2012 Bejar R, Stevenson KE, Stojanov P, Zaneveld JE, Bar-Natan M, Caughey B, Wang H, Garcia-Manero G, Kantarjian HM, Cutler C, Ritz J, Cibulskis K, Getz G, Steensma DP, Stone RM, ... ... Ebert BL, et al. Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation Blood. 120: 311-311. DOI: 10.1182/Blood.V120.21.311.311  0.326
2011 Ebert B, Bernard OA. Mutations in RNA splicing machinery in human cancers. The New England Journal of Medicine. 365: 2534-5. PMID 22150007 DOI: 10.1056/Nejme1111584  0.33
2011 Ashton JM, Balys M, Neering S, Cowley G, Root DE, Miller PG, Ebert B, McMurray H, Hassane DC, Land H, Jordan CT. Oncogene Cooperativity Analysis Reveals a Novel Set of Genes That Regulate the In Vivo Growth and Survival of Leukemia Stem Cells Blood. 118: 553-553. DOI: 10.1182/Blood.V118.21.553.553  0.369
2011 Bejar R, Stevenson K, Abdel-Wahab O, Galili N, Nilsson B, Garcia-Manero G, Kantarjian H, Raza A, Levine R, Neuberg D, Ebert B. 288 Point mutations in myelodysplastic syndromes: Associations with clinical features and independent predictors of overall survival Leukemia Research. 35: S113. DOI: 10.1016/S0145-2126(11)70290-9  0.322
2010 Bejar R, Stevenson K, Abdel-Wahab O, Marie M, Lin K, McAuley JR, Cheung K, Galili N, Garcia-Manero G, Kantarjian H, Raza A, Levine R, Neuberg D, Ebert BL. Point Mutations In Myelodysplastic Syndromes Are Associated with Clinical Features and Are Independent Predictors of Overall Survival Blood. 116: 300-300. DOI: 10.1182/Blood.V116.21.300.300  0.304
1997 Ratcliffe PJ, Ebert BL, Firth JD, Gleadle JM, Maxwell PH, Nagao M, O'Rourke JF, Pugh CW, Wood SM. Oxygen regulated gene expression: erythropoietin as a model system. Kidney International. 51: 514-26. PMID 9027732 DOI: 10.1038/Ki.1997.72  0.398
1996 Nagao M, Ebert BL, Ratcliffe PJ, Pugh CW. Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-binding sites. Febs Letters. 387: 161-6. PMID 8674541 DOI: 10.1016/0014-5793(96)00484-X  0.417
1996 Ebert BL, Gleadle JM, O'Rourke JF, Bartlett SM, Poulton J, Ratcliffe PJ. Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin. The Biochemical Journal. 809-14. PMID 8611159 DOI: 10.1042/Bj3130809  0.414
1996 Gleadle JM, Ebert BL, Ratcliffe PJ. Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing. European Journal of Biochemistry. 234: 92-9. PMID 8529674 DOI: 10.1111/J.1432-1033.1995.092_C.X  0.472
1996 Ebert BL, Firth JD, Ratcliffe PJ. Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences. The Journal of Biological Chemistry. 270: 29083-9. PMID 7493931 DOI: 10.1074/Jbc.270.49.29083  0.413
1995 Firth JD, Ebert BL, Ratcliffe PJ. Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements. The Journal of Biological Chemistry. 270: 21021-7. PMID 7673128 DOI: 10.1074/Jbc.270.36.21021  0.443
1995 Ratcliffe PJ, Ebert BL, Ferguson DJ, Firth JD, Gleadle JM, Maxwell PH, Pugh CW. Regulation of the erythropoietin gene. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 18-27. PMID 7644101 DOI: 10.1093/Ndt/10.Supp2.18  0.397
1995 Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ. Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. The American Journal of Physiology. 268: C1362-8. PMID 7541940 DOI: 10.1152/Ajpcell.1995.268.6.C1362  0.419
1995 Gleadle J, Ebert B, Firth J, Ratcliffe P. Oxygen Sensing and Vascular Growth Factor Gene Expression: Comparison with Erythropoietin Regulation Clinical Science. 88. DOI: 10.1042/Cs088002Pa  0.461
1994 Pugh CW, Ebert BL, Ebrahim O, Maxwell PH, Ratcliffe PJ, Caro J, Acker H, Goldwasser E. Analysis of cis-acting sequences required for operation of the erythropoietin 3' enhancer in different cell lines Annals of the New York Academy of Sciences. 718: 31-40. PMID 8185238 DOI: 10.1111/J.1749-6632.1994.Tb55701.X  0.406
1994 Pugh CW, Ebert BL, Ebrahim O, Ratcliffe PJ. Characterisation of functional domains within the mouse erythropoietin 3' enhancer conveying oxygen-regulated responses in different cell lines. Biochimica Et Biophysica Acta. 1217: 297-306. PMID 8148375 DOI: 10.1016/0167-4781(94)90289-5  0.431
1994 Firth JD, Ebert BL, Pugh CW, Ratcliffe PJ. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. Proceedings of the National Academy of Sciences of the United States of America. 91: 6496-500. PMID 8022811 DOI: 10.1073/Pnas.91.14.6496  0.445
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