| Year |
Citation |
Score |
| 2023 |
Jin JC, Chen BY, Deng CH, Chen JN, Xu F, Tao Y, Hu CL, Xu CH, Chang BH, Wang Y, Fei MY, Liu P, Yu PC, Li ZJ, Li XY, et al. deficiency impairs HSPC homeostasis and erythropoiesis via and predicts poor prognosis in MDS. Science Advances. 9: eadi7375. PMID 38019913 DOI: 10.1126/sciadv.adi7375 |
0.331 |
|
| 2023 |
Ahmad MH, Hegde M, Wong WJ, M Hosseini M, Garrett LJ, Carrascoso A, Issac N, Ebert BL, Silva JC, Pihan G, Zhu LJ, Wolfe S, Agarwal A, Liu PP, Castilla LH. Runx1-R188Q germline mutation induces inflammation and predisposition to hematologic malignancies in mice. Blood Advances. PMID 37756546 DOI: 10.1182/bloodadvances.2023010398 |
0.693 |
|
| 2023 |
Yang J, Liu Y, Yin H, Xie S, Zhang L, Dong X, Ni H, Bu W, Ma H, Liu P, Zhu H, Guo R, Sun L, Wu Y, Qin J, et al. HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells. Embo Reports. e56009. PMID 37642636 DOI: 10.15252/embr.202256009 |
0.321 |
|
| 2023 |
Zezulin AU, Yen D, Ye D, Howell ED, Bresciani E, Diemer J, Ren JG, Ahmad MH, Castilla LH, Touw IP, Minn AJ, Tong W, Liu PP, Tan K, Yu W, et al. RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils. Genes & Development. PMID 37536952 DOI: 10.1101/gad.350418.123 |
0.625 |
|
| 2023 |
Fei MY, Wang Y, Chang BH, Xue K, Dong F, Huang D, Li XY, Li ZJ, Hu CL, Liu P, Wu JC, Yu PC, Hong MH, Chen SB, Xu CH, et al. The cell non-autonomous function of ID1 promotes AML progression via ANGPTL7 from the microenvironment. Blood. PMID 37319434 DOI: 10.1182/blood.2022019537 |
0.331 |
|
| 2023 |
Xu J, Zhong A, Zhang S, Chen M, Zhang L, Hang X, Zheng J, Wu B, Deng X, Pan X, Wang Z, Qi L, Shi K, Li S, Wang Y, ... ... Liu P, et al. KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2206098. PMID 37142882 DOI: 10.1002/advs.202206098 |
0.348 |
|
| 2023 |
Zheng J, Wang Z, Pan X, Zhang Z, Li H, Deng X, Liu P, Zhang Q, Na F, Chen C, Niu T, Liu Y. DNMT3A accelerates angioimmunoblastic T-cell lymphoma in mice. Oncogene. PMID 37127775 DOI: 10.1038/s41388-023-02699-2 |
0.303 |
|
| 2023 |
Zezulin AU, Ye D, Howell E, Yen D, Bresciani E, Diemer J, Ren JG, Ahmad MH, Castilla LH, Touw IP, Minn AJ, Tong W, Liu PP, Tan K, Yu W, et al. RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils. Biorxiv : the Preprint Server For Biology. PMID 36747636 DOI: 10.1101/2023.01.27.525911 |
0.626 |
|
| 2022 |
Chai W, Hao W, Liu J, Han Z, Chang S, Cheng L, Sun M, Yan G, Liu Z, Liu Y, Zhang G, Xing L, Chen H, Liu P. Visualizing Cathepsin K-Cre Expression at the Single-Cell Level with GFP Reporters. Jbmr Plus. 7: e10706. PMID 36699636 DOI: 10.1002/jbm4.10706 |
0.313 |
|
| 2022 |
Wang F, Huang X, Sun Y, Li Z, Sun R, Zhao T, Wang M, Yan C, Liu P. Sulforaphane regulates the proliferation of leukemia stem-like cells via Sonic Hedgehog signaling pathway. European Journal of Pharmacology. 919: 174824. PMID 35157913 DOI: 10.1016/j.ejphar.2022.174824 |
0.3 |
|
| 2021 |
Bresciani E, Carrington B, Yu K, Kim EMK, Zhen T, Guzman VS, Broadbridge E, Bishop K, Kirby M, Harper U, Wincovitch S, Dell'Orso S, Sartorelli V, Sood R, Liu PP. Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development. Blood Advances. PMID 34492681 DOI: 10.1182/bloodadvances.2020003969 |
0.328 |
|
| 2021 |
Estevez B, Borst S, Jarocha DJ, Sudunagunta VS, Gonzalez M, Garifallou J, Hakonarson H, Gao P, Tan K, Liu PP, Bagga S, Holdreith N, Tong W, Speck NA, French DL, et al. RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells. Blood. PMID 33569577 DOI: 10.1182/blood.2020006389 |
0.301 |
|
| 2020 |
Zhen T, Cao Y, Ren G, Zhao L, Hyde RK, Lopez G, Feng D, Alemu L, Zhao K, Liu PP. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development. Blood. PMID 32929473 DOI: 10.1182/Blood.2020007747 |
0.509 |
|
| 2020 |
Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, ... ... Liu PP, et al. CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883883 DOI: 10.1073/Pnas.2003228117 |
0.412 |
|
| 2020 |
Chen BY, Song J, Hu CL, Chen SB, Zhang Q, Xu CH, Wu JC, Hou D, Sun M, Zhang YL, Liu N, Yu PC, Liu P, Zong LJ, Zhang JY, et al. SETD2 deficiency predicts poor prognosis in MDS and accelerated MDS-associated leukemogenesis via S100a9. Blood. PMID 32202636 DOI: 10.1182/blood.2019001963 |
0.332 |
|
| 2019 |
McElderry J, Carrington B, Bishop K, Kim E, Pei W, Chen Z, Ramanagoudr-Bhojappa R, Prakash A, Burgess SM, Liu PP, Sood R. Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage. Human Molecular Genetics. PMID 31691804 DOI: 10.1093/Hmg/Ddz261 |
0.397 |
|
| 2019 |
Saida S, Zhen T, Kim E, Yu K, Lopez G, McReynolds LJ, Liu PP. Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice. Leukemia. PMID 31624376 DOI: 10.1038/s41375-019-0605-7 |
0.374 |
|
| 2019 |
Geng YM, Liu CX, Lu WY, Liu P, Yuan PY, Liu WL, Xu PP, Shen XQ. LAPTM5 is transactivated by RUNX2 and involved in RANKL trafficking in osteoblastic cells. Molecular Medicine Reports. PMID 31545469 DOI: 10.3892/mmr.2019.10688 |
0.301 |
|
| 2018 |
Fei DL, Zhen T, Durham B, Ferrarone J, Zhang T, Garrett L, Yoshimi A, Abdel-Wahab O, Bradley RK, Liu P, Varmus H. Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene . Proceedings of the National Academy of Sciences of the United States of America. PMID 30322915 DOI: 10.1073/Pnas.1812669115 |
0.333 |
|
| 2017 |
Morita K, Maeda S, Suzuki K, Kiyose H, Taniguchi J, Liu PP, Sugiyama H, Adachi S, Kamikubo Y. Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions. Blood Advances. 1: 1440-1451. PMID 29296785 DOI: 10.1182/Bloodadvances.2017007591 |
0.452 |
|
| 2017 |
Jiang X, Hu C, Ferchen K, Nie J, Cui X, Chen CH, Cheng L, Zuo Z, Seibel W, He C, Tang Y, Skibbe JR, Wunderlich M, Reinhold WC, Dong L, ... ... Liu PP, et al. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nature Communications. 8: 2099. PMID 29235481 DOI: 10.1038/S41467-017-02290-W |
0.303 |
|
| 2017 |
Morita K, Noura M, Tokushige C, Maeda S, Kiyose H, Kashiwazaki G, Taniguchi J, Bando T, Yoshida K, Ozaki T, Matsuo H, Ogawa S, Liu PP, Nakahata T, Sugiyama H, et al. Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells. Scientific Reports. 7: 16604. PMID 29192243 DOI: 10.1038/S41598-017-16799-Z |
0.396 |
|
| 2017 |
Li Y, Jin C, Bai H, Gao Y, Sun S, Chen L, Qin L, Liu PP, Cheng L, Wang QF. Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation. Blood. PMID 29101237 DOI: 10.1182/Blood-2017-04-780379 |
0.315 |
|
| 2017 |
Zhen T, Kwon E, Zhao L, Hsu J, Hyde RK, Lu Y, Alemu L, Speck NA, Liu PP. CHD7 deficiency delays leukemogenesis in mice induced by CBFB-MYH11. Blood. PMID 29018080 DOI: 10.1182/Blood-2017-04-780106 |
0.448 |
|
| 2016 |
Zhen T, Fei DL, Zhao L, Lopez G, Varmus H, Liu PP. Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model Blood. 128: 964-964. DOI: 10.1182/Blood.V128.22.964.964 |
0.418 |
|
| 2016 |
Zhen T, Kwon EM, Hyde RK, Zhao L, Lopez G, Alemu L, Liu PP. Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development Blood. 128: 2722-2722. DOI: 10.1182/Blood.V128.22.2722.2722 |
0.471 |
|
| 2016 |
Wang Y, Hannon K, Richter L, Becker M, Garett L, Rivas C, Alemu L, Zhao L, Liu PP, Hyde RK. RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML Blood. 128: 2715-2715. DOI: 10.1182/Blood.V128.22.2715.2715 |
0.484 |
|
| 2015 |
Zhao L, Alemu L, Cheng J, Zhen T, Friedman AD, Liu PP. The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis Blood. 126: 3666-3666. DOI: 10.1182/Blood.V126.23.3666.3666 |
0.473 |
|
| 2015 |
Zhen T, Zhao L, Hyde RK, Alemu L, Liu PP. CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis Blood. 126: 3662-3662. DOI: 10.1182/Blood.V126.23.3662.3662 |
0.404 |
|
| 2015 |
Chou B, Bai H, Gao Y, Wang Y, Ye Z, Kwon EM, Liu PP, Friedman AD, Wang ZZ, Cheng L. The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model Blood. 126: 1167-1167. DOI: 10.1182/Blood.V126.23.1167.1167 |
0.429 |
|
| 2014 |
Connelly JP, Kwon EM, Gao Y, Trivedi NS, Elkahloun AG, Horwitz MS, Cheng L, Liu PP. Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Blood. 124: 1926-30. PMID 25114263 DOI: 10.1182/Blood-2014-01-550525 |
0.402 |
|
| 2014 |
Bresciani E, Carrington B, Wincovitch S, Jones M, Gore AV, Weinstein BM, Sood R, Liu PP. CBFβ and RUNX1 are required at 2 different steps during the development of hematopoietic stem cells in zebrafish. Blood. 124: 70-8. PMID 24850758 DOI: 10.1182/Blood-2013-10-531988 |
0.406 |
|
| 2014 |
Zhao L, Alemu L, Cheng J, Zhen T, Friedman AD, Liu PP. Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis Blood. 124: 2218-2218. DOI: 10.1182/Blood.V124.21.2218.2218 |
0.436 |
|
| 2013 |
Hyde RK, Liu PP. Germline PAX5 mutations and B cell leukemia. Nature Genetics. 45: 1104-5. PMID 24071841 DOI: 10.1038/Ng.2778 |
0.342 |
|
| 2013 |
Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link KA, Mizukawa B, Grimes HL, Kurokawa M, Liu PP, Huang G, et al. Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells. The Journal of Clinical Investigation. 123: 3876-88. PMID 23979164 DOI: 10.1172/Jci68557 |
0.445 |
|
| 2013 |
Kamikubo Y, Hyde RK, Zhao L, Alemu L, Rivas C, Garrett LJ, Liu PP. The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis. Blood. 121: 638-42. PMID 23152542 DOI: 10.1182/Blood-2012-06-434688 |
0.36 |
|
| 2013 |
Kwon EM, Connelly JP, Gao Y, Horwitz M, Cheng L, Liu PP. Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation Blood. 122: 738-738. DOI: 10.1182/Blood.V122.21.738.738 |
0.399 |
|
| 2013 |
Zhao L, Hyde RK, Alemu L, Liu PP. Abstract 3850: The interaction of RUNX1 with CBFβ-SMMHC during leukemogenesis. Cancer Research. 73: 3850-3850. DOI: 10.1158/1538-7445.Am2013-3850 |
0.469 |
|
| 2012 |
Jin H, Li L, Xu J, Zhen F, Zhu L, Liu PP, Zhang M, Zhang W, Wen Z. Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood. 119: 5239-49. PMID 22493295 DOI: 10.1182/Blood-2011-12-398362 |
0.392 |
|
| 2012 |
English MA, Lei L, Blake T, Wincovitch SM, Sood R, Azuma M, Hickstein D, Liu PP. Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 879-89. PMID 22411201 DOI: 10.1002/Dvdy.23774 |
0.418 |
|
| 2012 |
Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, Ye Z, Chandrasekharappa SC, Yang H, Mullikin JC, ... Liu PP, et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell. 10: 337-44. PMID 22385660 DOI: 10.1016/J.Stem.2012.01.005 |
0.319 |
|
| 2012 |
Zhao L, Melenhorst JJ, Alemu L, Kirby M, Anderson S, Kench M, Hoogstraten-Miller S, Brinster L, Kamikubo Y, Gilliland DG, Liu PP. KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice. Blood. 119: 1511-21. PMID 22160378 DOI: 10.1182/Blood-2011-02-338210 |
0.424 |
|
| 2012 |
Connelly JP, Horwitz MS, Liu PP. Towards Cell Therapy for FPD/AML with Patient-Specific IPS Cells Blood. 120: 4677-4677. DOI: 10.1182/Blood.V120.21.4677.4677 |
0.44 |
|
| 2012 |
Li Z, Zhang Z, Li Y, Arnovitz S, Chen P, Huang H, Jiang X, Hong G, He C, Wang C, Elkahloun A, Valk PJM, Dohner K, Neilly MB, Bullinger L, ... ... Liu PP, et al. The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL-Rearranged Acute Leukemia Blood. 120: 3522-3522. DOI: 10.1182/Blood.V120.21.3522.3522 |
0.493 |
|
| 2012 |
Hyde RK, Zhao L, Alemu L, Liu PP. Runx1 Is Required by the Inv(16) Fusion Gene Cbfb-MYH11. Blood. 120: 2434-2434. DOI: 10.1182/Blood.V120.21.2434.2434 |
0.498 |
|
| 2011 |
Hyde RK, Liu PP. GATA2 mutations lead to MDS and AML. Nature Genetics. 43: 926-7. PMID 21956389 DOI: 10.1038/Ng.949 |
0.343 |
|
| 2011 |
Chae JJ, Cho Y, Lee G, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL. Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice Immunity. 34: 755-768. PMID 21600797 DOI: 10.1016/J.Immuni.2011.02.020 |
0.371 |
|
| 2011 |
Hyde RK, Kamikubo Y, Zhao L, Alemu L, Garrett L, Liu PP. The C-Terminal of MYH11 Is Required for Cbfb-MYH11 Activity During Embryonic Hematopoiesis and Leukemogenesis Blood. 118: 2472-2472. DOI: 10.1182/Blood.V118.21.2472.2472 |
0.486 |
|
| 2011 |
Hyde RK, Zhao L, Alemu L, Liu PP. Runx1 Is Required for Cbfb-MYH11 Activity During Primitive Hematopoiesis Blood. 118: 1357-1357. DOI: 10.1182/Blood.V118.21.1357.1357 |
0.461 |
|
| 2010 |
Gill JA, Lowe L, Nguyen J, Liu PP, Blake T, Venkatesh B, Aplan PD. Enforced expression of Simian virus 40 large T-antigen leads to testicular germ cell tumors in zebrafish. Zebrafish. 7: 333-41. PMID 21158563 DOI: 10.1089/Zeb.2010.0663 |
0.41 |
|
| 2010 |
Hyde RK, Liu PP. RUNX1 repression-independent mechanisms of leukemogenesis by fusion genes CBFB-MYH11 and AML1-ETO (RUNX1-RUNX1T1). Journal of Cellular Biochemistry. 110: 1039-45. PMID 20589720 DOI: 10.1002/Jcb.22596 |
0.41 |
|
| 2010 |
Kamikubo Y, Zhao L, Wunderlich M, Corpora T, Hyde RK, Paul TA, Kundu M, Garrett L, Compton S, Huang G, Wolff L, Ito Y, Bushweller J, Mulloy JC, Liu PP. Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1. Cancer Cell. 17: 455-68. PMID 20478528 DOI: 10.1016/J.Ccr.2010.03.022 |
0.356 |
|
| 2010 |
Sood R, English MA, Belele CL, Jin H, Bishop K, Haskins R, McKinney MC, Chahal J, Weinstein BM, Wen Z, Liu PP. Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation. Blood. 115: 2806-9. PMID 20154212 DOI: 10.1182/Blood-2009-08-236729 |
0.345 |
|
| 2010 |
Hyde RK, Kamikubo Y, Anderson S, Kirby M, Alemu L, Zhao L, Liu PP. Cbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11. Blood. 115: 1433-43. PMID 20007544 DOI: 10.1182/Blood-2009-06-227413 |
0.513 |
|
| 2009 |
Belele CL, English MA, Chahal J, Burnetti A, Finckbeiner SM, Gibney G, Kirby M, Sood R, Liu PP. Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish. Blood. 114: 5162-72. PMID 19843882 DOI: 10.1182/Blood-2009-05-224709 |
0.339 |
|
| 2009 |
Novotny E, Compton S, Liu PP, Collins FS, Chandrasekharappa SC. In vitro hematopoietic differentiation of mouse embryonic stem cells requires the tumor suppressor menin and is mediated by Hoxa9. Mechanisms of Development. 126: 517-22. PMID 19393316 DOI: 10.1016/J.Mod.2009.04.001 |
0.553 |
|
| 2009 |
Jin H, Sood R, Xu J, Zhen F, English MA, Liu PP, Wen Z. Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI. Development (Cambridge, England). 136: 647-54. PMID 19168679 DOI: 10.1242/Dev.029637 |
0.386 |
|
| 2009 |
Zhao L, Melenhorst JJ, Alemu L, Kirby M, Anderson SM, Hoogstraten-Miller S, Kamikubo Y, Gilliland DG, Liu PP. C-KIT with D816Y/V Mutations Cooperate with CBFB-MYH11 to Accelerate Leukemogenesis in Mice. Blood. 114: 274-274. DOI: 10.1182/Blood.V114.22.274.274 |
0.414 |
|
| 2008 |
Hyde RK, Kamikubo Y, Alemu L, Zhao L, Wang C, Liu PP. Cbfb-MYH11 Can Block Hematopoiesis and Alter Gene Expression through Mechanisms Independent of Cbfb and Runx1 Repression Blood. 112: 747-747. DOI: 10.1182/Blood.V112.11.747.747 |
0.461 |
|
| 2008 |
Kamikubo Y, Garrett-Beal L, Kirby M, Liu PP. The C-Terminus of the CBFβ-SMMHC Fusion Protein Is Required for the Myeloblastic Transformation of inv16 Leukemia Blood. 112: 3799-3799. DOI: 10.1182/Blood.V112.11.3799.3799 |
0.5 |
|
| 2007 |
Markus J, Garin MT, Bies J, Galili N, Raza A, Thirman MJ, Le Beau MM, Rowley JD, Liu PP, Wolff L. Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16). Cancer Research. 67: 992-1000. PMID 17283131 DOI: 10.1158/0008-5472.Can-06-2964 |
0.384 |
|
| 2007 |
Zhao L, Cannons JL, Anderson S, Kirby M, Xu L, Castilla LH, Schwartzberg PL, Bosselut R, Liu PP. CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus. Blood. 109: 3432-40. PMID 17185462 DOI: 10.1182/Blood-2006-10-051508 |
0.711 |
|
| 2007 |
Kamikubo Y, Garrett-Beal L, Liu PP. Leukemogenesis by Truncated CBFβ-SMMHC Defective in Repressing RUNX1. Blood. 110: 462-462. DOI: 10.1182/Blood.V110.11.462.462 |
0.486 |
|
| 2007 |
Hyde RK, Kreycik CE, Liu PP. CBFB-Independent Activities of the Inv(16) Fusion Gene CBFB-MYH11. Blood. 110: 3376-3376. DOI: 10.1182/Blood.V110.11.3376.3376 |
0.453 |
|
| 2007 |
Sood R, English M, Belele C, Haskins R, Burnetti A, Chahal J, Liu PP. Identification of Three Phases of Hematopoieisis in Zebrafish and Their Differential Requirements for Runx1 and Gata1 Functions. Blood. 110: 202-202. DOI: 10.1182/Blood.V110.11.202.202 |
0.411 |
|
| 2006 |
Kuo YH, Landrette SF, Heilman SA, Perrat PN, Garrett L, Liu PP, Le Beau MM, Kogan SC, Castilla LH. Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia. Cancer Cell. 9: 57-68. PMID 16413472 DOI: 10.1016/J.Ccr.2005.12.014 |
0.715 |
|
| 2006 |
Zhao L, Cannons JL, Anderson S, Kirby MR, Xu L, Castilla L, Schwartzberg PL, Bosselut R, Liu PP. CBFB Is Required for Early T Cell Development in the Thymus. Blood. 108: 648-648. DOI: 10.1182/Blood.V108.11.648.648 |
0.715 |
|
| 2005 |
Kundu M, Compton S, Garrett-Beal L, Stacy T, Starost MF, Eckhaus M, Speck NA, Liu PP. Runx1 deficiency predisposes mice to T-lymphoblastic lymphoma. Blood. 106: 3621-4. PMID 16051740 DOI: 10.1182/Blood-2005-04-1447 |
0.505 |
|
| 2005 |
Bushweller JH, Gorczynski MJ, Grembecka J, Newman M, Corpora T, Zhou Y, Kong Y, Jeon J, Liu PP, Brown ML. Development of Small Molecule Inhibitors of the CBFβ-SMMHC Oncoprotein. Blood. 106: 3359-3359. DOI: 10.1182/Blood.V106.11.3359.3359 |
0.301 |
|
| 2005 |
Lee S, Chen J, Zhou G, Shi R, Kocherginsky M, Karrison TG, Kim YC, Ge X, Jayathilaka N, Neilly MB, Bouffard G, Young A, Kornblau S, Bloomfield C, Bohlander S, ... Liu PP, et al. Gene Expression Profiles in Acute Myeloid Leukemia (AML): From Diagnosis to Prognosis. Blood. 106: 2996-2996. DOI: 10.1182/Blood.V106.11.2996.2996 |
0.428 |
|
| 2004 |
Castilla LH, Perrat P, Martinez NJ, Landrette SF, Keys R, Oikemus S, Flanegan J, Heilman S, Garrett L, Dutra A, Anderson S, Pihan GA, Wolff L, Liu PP. Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 101: 4924-9. PMID 15044690 DOI: 10.1073/Pnas.0400930101 |
0.731 |
|
| 2004 |
Kuo Y, Heilman S, Chen A, Liu PP, Gernstein R, Kogan S, Castilla LH. Cbfb-MYH11 Induces Expansion of a Lin-Kit+Sca1- Abnormal Progenitor Compartment that Predisposes Acute Myeloid Leukemia in Mice. Blood. 104: 543-543. DOI: 10.1182/Blood.V104.11.543.543 |
0.778 |
|
| 2004 |
Zhao L, Cannons JL, Castilla LH, Schwartzberg PL, Liu PP. The Role of CBFβ in T Cell Development. Blood. 104: 3234-3234. DOI: 10.1182/Blood.V104.11.3234.3234 |
0.723 |
|
| 2004 |
Lee S, Chen J, Zhou G, Touma E, Shi R, Sun M, Kocherginsky M, Karrison TG, Kim YC, Ge X, Jayathilaka N, Emmanuel N, Bouffard G, Dietrich N, Young A, ... ... Liu PP, et al. Gene Expression Profiles in Acute Myeloid Leukemias (AML): A Novel Approach Using SAGE and Custom Microarray. Blood. 104: 197-197. DOI: 10.1182/Blood.V104.11.197.197 |
0.444 |
|
| 2003 |
Huang G, Shigesada K, Wee HJ, Liu PP, Osato M, Ito Y. Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera. Blood. 103: 3200-7. PMID 15070703 DOI: 10.1182/Blood-2003-07-2188 |
0.335 |
|
| 2003 |
Nishikawa K, Kobayashi M, Masumi A, Lyons SE, Weinstein BM, Liu PP, Yamamoto M. Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos. Molecular and Cellular Biology. 23: 8295-305. PMID 14585986 DOI: 10.1128/Mcb.23.22.8295-8305.2003 |
0.41 |
|
| 2003 |
Kundu M, Liu PP. Cbfβ is involved in maturation of all lineages of hematopoietic cells during embryogenesis except erythroid Blood Cells Molecules and Diseases. 30: 164-169. PMID 12732179 DOI: 10.1016/S1079-9796(03)00030-5 |
0.431 |
|
| 2003 |
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Molecular Cell. 11: 591-604. PMID 12667444 DOI: 10.1016/S1097-2765(03)00056-X |
0.362 |
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| 2002 |
Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP. Cbfbeta interacts with Runx2 and has a critical role in bone development. Nature Genetics. 32: 639-44. PMID 12434156 DOI: 10.1038/Ng1050 |
0.44 |
|
| 2002 |
Lukasik SM, Zhang L, Corpora T, Tomanicek S, Li Y, Kundu M, Hartman K, Liu PP, Laue TM, Biltonen RL, Speck NA, Bushweller JH. Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis. Nature Structural Biology. 9: 674-9. PMID 12172539 DOI: 10.1038/Nsb831 |
0.316 |
|
| 2002 |
Lyons SE, Lawson ND, Lei L, Bennett PE, Weinstein BM, Liu PP. A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. Proceedings of the National Academy of Sciences of the United States of America. 99: 5454-9. PMID 11960002 DOI: 10.1073/Pnas.082695299 |
0.414 |
|
| 2001 |
Kundu M, Liu PP. Function of the inv(16) fusion gene CBFB-MYH11. Current Opinion in Hematology. 8: 201-205. PMID 11561156 DOI: 10.1097/00062752-200107000-00004 |
0.41 |
|
| 2001 |
Lyons SE, Shue BC, Oates AC, Zon LI, Liu PP. A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain. Blood. 97: 2611-7. PMID 11313249 DOI: 10.1182/Blood.V97.9.2611 |
0.353 |
|
| 2001 |
Miller JD, Stacy T, Liu PP, Speck NA. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells. Blood. 97: 2248-56. PMID 11290585 DOI: 10.1182/Blood.V97.8.2248 |
0.481 |
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| 2000 |
Blake T, Adya N, Kim CH, Oates AC, Zon L, Chitnis A, Weinstein BM, Liu PP. Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scl and gata-1 in hematopoiesis. Blood. 96: 4178-84. PMID 11110689 DOI: 10.1182/Blood.V96.13.4178 |
0.433 |
|
| 2000 |
Chae JJ, Centola M, Aksentijevich I, Dutra A, Tran M, Wood G, Nagaraju K, Kingma DW, Liu PP, Kastner DL. Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever Mammalian Genome. 11: 428-435. PMID 10818206 DOI: 10.1007/S003350010082 |
0.386 |
|
| 1999 |
Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, Owens J, Eckhaus M, Bodine D, Liu PP. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nature Genetics. 23: 144-6. PMID 10508507 DOI: 10.1038/13776 |
0.72 |
|
| 1998 |
Centola M, Chen X, Sood R, Deng Z, Aksentijevich I, Blake T, Ricke DO, Chen X, Wood G, Zaks N, Richards N, Krizman D, Mansfield E, Apostolou S, Liu J, ... ... Liu PP, et al. Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3. Genome Research. 8: 1172-91. PMID 9847080 DOI: 10.1101/Gr.8.11.1172 |
0.482 |
|
| 1998 |
Adya N, Stacy T, Speck NA, Liu PP. The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates. Molecular and Cellular Biology. 18: 7432-43. PMID 9819429 DOI: 10.1128/Mcb.18.12.7432 |
0.402 |
|
| 1998 |
Cao W, Adya N, Britos-Bray M, Liu PP, Friedman AD. The Core Binding Factor (CBF) α Interaction Domain and the Smooth Muscle Myosin Heavy Chain (SMMHC) Segment of CBFβ-SMMHC Are Both Required to Slow Cell Proliferation Journal of Biological Chemistry. 273: 31534-31540. PMID 9813068 DOI: 10.1074/Jbc.273.47.31534 |
0.328 |
|
| 1998 |
Britos-Bray M, Ramirez M, Cao W, Wang X, Liu PP, Civin CI, Friedman AD. CBFβ-SMMHC, Expressed in M4eo Acute Myeloid Leukemia, Reduces p53 Induction and Slows Apoptosis in Hematopoietic Cells Exposed to DNA-Damaging Agents Blood. 92: 4344-4352. DOI: 10.1182/Blood.V92.11.4344.423A01_4344_4352 |
0.329 |
|
| 1997 |
Yamanaka R, Barlow C, Lekstrom-Himes J, Castilla LH, Liu PP, Eckhaus M, Decker T, Wynshaw-Boris A, Xanthopoulos KG. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13187-13192. PMID 9371821 DOI: 10.1073/Pnas.94.24.13187 |
0.687 |
|
| 1997 |
Balow JE, Shelton DA, Orsborn A, Mangelsdorf M, Aksentijevich I, Blake T, Sood R, Gardner D, Liu R, Pras E, Levy EN, Centola M, Deng Z, Zaks N, Wood G, ... ... Liu PP, et al. A high-resolution genetic map of the familial Mediterranean fever candidate region allows identification of haplotype-sharing among ethnic groups. Genomics. 44: 280-91. PMID 9325049 DOI: 10.1006/Geno.1997.4860 |
0.457 |
|
| 1997 |
Cao W, Britos-Bray M, Claxton DF, Kelley CA, Speck NA, Liu PP, Friedman AD. CBFβ-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells Oncogene. 15: 1315-1327. PMID 9315100 DOI: 10.1038/Sj.Onc.1201305 |
0.361 |
|
| 1997 |
Aksentijevich I, Centola M, Deng Z, Sood R, Balow J.E. J, Wood G, Zaks N, Mansfield E, Chen X, Eisenberg S, Vedula A, Shafran N, Raben N, Pras E, Pras M, ... ... Liu PP, et al. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever Cell. 90: 797-807. PMID 9288758 DOI: 10.1016/S0092-8674(00)80539-5 |
0.52 |
|
| 1997 |
Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, Huang X, Bushweller JH, Bories JC, Alt FW, Ryan G, Liu PP, Wynshaw-Boris A, Binder M, Marín-Padilla M, Sharpe AH, et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 87: 697-708. PMID 8929538 DOI: 10.1016/S0092-8674(00)81389-6 |
0.381 |
|
| 1996 |
Castilla LH, Wijmenga C, Wang Q, Stacy T, Speck NA, Eckhaus M, Marín-Padilla M, Collins FS, Wynshaw-Boris A, Liu PP. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell. 87: 687-96. PMID 8929537 DOI: 10.1016/S0092-8674(00)81388-4 |
0.751 |
|
| 1996 |
Liu PP, Wijmenga C, Hajra A, Blake TB, Kelley CA, Adelstein RS, Bagg A, Rector J, Cotelingam J, Willman CL, Collins FS. Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells. Genes, Chromosomes & Cancer. 16: 77-87. PMID 8818654 DOI: 10.1002/(Sici)1098-2264(199606)16:2<77::Aid-Gcc1>3.0.Co;2-# |
0.558 |
|
| 1996 |
Wijmenga C, Gregory PE, Hajra A, Schröck E, Ried T, Eils R, Liu PP, Collins FS. Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 1630-5. PMID 8643682 DOI: 10.1073/Pnas.93.4.1630 |
0.519 |
|
| 1995 |
Liu PP, Hajra A, Wijmenga C, Collins FS. Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia Blood. 85: 2289-2302. PMID 7727763 DOI: 10.1182/Blood.V85.9.2289.Bloodjournal8592289 |
0.595 |
|
| 1994 |
Liu P, Seidel N, Bodine D, Speck N, Tarlé S, Collins FS. Acute myeloid leukemia with Inv (16) produces a chimeric transcription factor with a myosin heavy chain tail. Cold Spring Harbor Symposia On Quantitative Biology. 59: 547-53. PMID 7587111 DOI: 10.1101/Sqb.1994.059.01.061 |
0.485 |
|
| 1994 |
Claxton D, Liu P, Hsu H, Marlton P, Hester J, Collins F, Deisseroth A, Rowley J, Siciliano M. Detection of Fusion Transcripts Generated by the Inversion 16 Chromosome in Acute Myelogenous Leukemia Blood. 83: 1750-1756. DOI: 10.1182/Blood.V83.7.1750.Bloodjournal8371750 |
0.379 |
|
| 1993 |
Liu P, Siciliano J, White B, Legerski RJ, Callen D, Reeders S, Siciliano MJ, Thompson LH. Regional mapping of human DNA excision repair gene ERCC4 to chromosome 16pl3.13–pl3.2 Mutagenesis. 8: 199-205. PMID 8332082 DOI: 10.1093/Mutage/8.3.199 |
0.309 |
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