| Year |
Citation |
Score |
| 2022 |
Kim KB, Kabra A, Kim DW, Xue Y, Huang Y, Hou PC, Zhou Y, Miranda LJ, Park JI, Shi X, Bender TP, Bushweller JH, Park KS. KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer. Science Advances. 8: eabl4618. PMID 35171684 DOI: 10.1126/sciadv.abl4618 |
0.591 |
|
| 2018 |
Zhou Y, Bushweller JH. Solution structure and elevator mechanism of the membrane electron transporter CcdA. Nature Structural & Molecular Biology. PMID 29379172 DOI: 10.1038/S41594-018-0022-Z |
0.573 |
|
| 2017 |
Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH. A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells. Leukemia & Lymphoma. 1-13. PMID 29249175 DOI: 10.1080/10428194.2017.1410882 |
0.627 |
|
| 2017 |
Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, et al. Corrigendum to: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers" [EBioMedicine 8 (2016) 117-131]. Ebiomedicine. PMID 29104075 DOI: 10.1016/J.Ebiom.2017.10.029 |
0.615 |
|
| 2016 |
Ren J, Xu W, Tang L, Su M, Chen D, Chen YL, Zang Y, Li J, Shen J, Zhou Y, Xiong B. Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface. Bioorganic & Medicinal Chemistry Letters. PMID 27528435 DOI: 10.1016/J.Bmcl.2016.07.074 |
0.341 |
|
| 2016 |
Illendula A, Gilmour J, Grembecka J, Tirumala VS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. Ebiomedicine. 8: 117-131. PMID 27428424 DOI: 10.1016/J.Ebiom.2016.04.032 |
0.671 |
|
| 2016 |
Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers Ebiomedicine. DOI: 10.1016/j.ebiom.2016.04.032 |
0.646 |
|
| 2015 |
Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science (New York, N.Y.). 347: 779-84. PMID 25678665 DOI: 10.1126/Science.Aaa0314 |
0.662 |
|
| 2012 |
Bushweller JH, Illendula A, Pulikkan JA, Grembecka J, Bradley P, Zhou Y, Xue L, Gao Y, Castilla LH. A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv(16) Leukemia in Vivo Blood. 120: 286-286. DOI: 10.1182/Blood.V120.21.286.286 |
0.633 |
|
| 2011 |
Chen H, Ji F, Olman V, Mobley CK, Liu Y, Zhou Y, Bushweller JH, Prestegard JH, Xu Y. Optimal mutation sites for PRE data collection and membrane protein structure prediction. Structure (London, England : 1993). 19: 484-95. PMID 21481772 DOI: 10.1016/J.Str.2011.02.002 |
0.689 |
|
| 2010 |
Früh V, Zhou Y, Chen D, Loch C, Ab E, Grinkova YN, Verheij H, Sligar SG, Bushweller JH, Siegal G. Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB. Chemistry & Biology. 17: 881-91. PMID 20797617 DOI: 10.1016/J.Chembiol.2010.06.011 |
0.632 |
|
| 2008 |
Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Molecular Cell. 31: 896-908. PMID 18922471 DOI: 10.1016/J.Molcel.2008.08.028 |
0.713 |
|
| 2008 |
Zhou Y, Cierpicki T, Jimenez RHF, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. Solution NMR structure of integral membrane protein DsbB Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K73/Pdb |
0.378 |
|
| 2007 |
Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, et al. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chemistry & Biology. 14: 1186-97. PMID 17961830 DOI: 10.1016/J.Chembiol.2007.09.006 |
0.728 |
|
| 2007 |
Matheny CJ, Speck ME, Cushing PR, Zhou Y, Corpora T, Regan M, Newman M, Roudaia L, Speck CL, Gu TL, Griffey SM, Bushweller JH, Speck NA. Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. The Embo Journal. 26: 1163-75. PMID 17290219 DOI: 10.1038/Sj.Emboj.7601568 |
0.677 |
|
| 2007 |
Bushweller JH, Zhou Y, Cierpicki T. Solution NMR structure and dynamics of the integral membrane enzyme DsbB ‐ insights into periplasmic disulfide bond formation The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A148-B |
0.569 |
|
| 2005 |
Bushweller JH, Gorczynski MJ, Grembecka J, Newman M, Corpora T, Zhou Y, Kong Y, Jeon J, Liu PP, Brown ML. Development of Small Molecule Inhibitors of the CBFβ-SMMHC Oncoprotein. Blood. 106: 3359-3359. DOI: 10.1182/Blood.V106.11.3359.3359 |
0.733 |
|
| 2005 |
Grembecka J, Graf K, Newman M, Zhou Y, Cheney M, Speck NA, Brown ML, Bushweller JH. Development of Small Molecule Inhibitor of the AML1-ETO Oncoprotein. Blood. 106: 1515-1515. DOI: 10.1182/Blood.V106.11.1515.1515 |
0.511 |
|
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