| Year |
Citation |
Score |
| 2024 |
Shimagaki KS, Lynch RM, Barton JP. Parallel HIV-1 evolutionary dynamics in humans and rhesus macaques who develop broadly neutralizing antibodies. Biorxiv : the Preprint Server For Biology. PMID 39071321 DOI: 10.1101/2024.07.12.603090 |
0.561 |
|
| 2024 |
Premazzi Papa M, Mendoza-Torres E, Sun P, Encinales L, Goulet J, Defang G, Vihasi J, Cheng Y, Suchowiecki K, Rosales W, Amdur R, Porras-Ramirez A, Rico-Mendoza A, Herrera Gomez C, Nicholes S, ... ... Lynch RM, et al. Dengue NS1 antibodies are associated with clearance of viral NS1. The Journal of Infectious Diseases. PMID 38842497 DOI: 10.1093/infdis/jiae299 |
0.352 |
|
| 2024 |
Whitehill GD, Joy J, Marino FE, Krause RJ, Mallick S, Courtney HM, Park K, Carey JW, Hoh R, Hartig H, Pae V, Sarvadhavabhatla S, Donaire MSB, Deeks SG, Lynch RM, et al. Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1. The Journal of Clinical Investigation. PMID 38652564 DOI: 10.1172/JCI176673 |
0.445 |
|
| 2023 |
Vukovich MJ, Raju N, Kgagudi P, Manamela NP, Abu-Shmais AA, Gripenstraw KR, Wasdin PT, Shen X, Dwyer B, Akoad J, Lynch RM, Montefiori DC, Richardson SI, Moore PL, Georgiev IS. Development of LIBRA-seq for the guinea pig model system as a tool for the evaluation of antibody responses to multivalent HIV-1 vaccines. Journal of Virology. e0147823. PMID 38085509 DOI: 10.1128/jvi.01478-23 |
0.304 |
|
| 2023 |
Williamson C, Lynch RM, Moore PL. Anticipating HIV viral escape - resistance to active and passive immunization. Current Opinion in Hiv and Aids. PMID 37678357 DOI: 10.1097/COH.0000000000000816 |
0.413 |
|
| 2023 |
Sankhala RS, Dussupt V, Donofrio G, Gromowski GD, De La Barrera RA, Larocca RA, Mendez-Rivera L, Lee A, Choe M, Zaky W, Mantus G, Jensen JL, Chen WH, Gohain N, Bai H, ... ... Lynch RM, et al. Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Reports. 42: 112942. PMID 37561630 DOI: 10.1016/j.celrep.2023.112942 |
0.371 |
|
| 2023 |
Ghofrani J, Bowen A, Chen J, Balakrishnan PB, Powell AB, Cherukula K, Cruz CRY, Jones RB, Lynch RM, Sweeney EE, Fernandes R. Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent HIV. International Journal of Nanomedicine. 18: 4055-4066. PMID 37520301 DOI: 10.2147/IJN.S401304 |
0.492 |
|
| 2023 |
Lynch RM, Bar KJ. Development of screening assays for use of broadly neutralizing antibodies in people with HIV. Current Opinion in Hiv and Aids. 18: 171-177. PMID 37265260 DOI: 10.1097/COH.0000000000000798 |
0.413 |
|
| 2022 |
Wilson A, Manuzak J, Liang H, Leda AR, Klatt NR, Lynch R. Probiotic therapy during vaccination alters antibody response to SHIV infection but not to commensals. Aids Research and Human Retroviruses. PMID 36517984 DOI: 10.1089/AID.2022.0123 |
0.439 |
|
| 2022 |
Stevenson EM, Terry S, Copertino D, Leyre L, Danesh A, Weiler J, Ward AR, Khadka P, McNeil E, Bernard K, Miller IG, Ellsworth GB, Johnston CD, Finkelsztein EJ, Zumbo P, ... ... Lynch RM, et al. SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8 T-cells. Nature Communications. 13: 4888. PMID 35985993 DOI: 10.1038/s41467-022-32376-z |
0.442 |
|
| 2021 |
Wilson A, Shakhtour L, Ward A, Ren Y, Recarey M, Stevenson E, Korom M, Kovacs C, Benko E, Jones RB, Lynch RM. Characterizing the Relationship Between Neutralization Sensitivity and Gene Diversity During ART Suppression. Frontiers in Immunology. 12: 710327. PMID 34603284 DOI: 10.3389/fimmu.2021.710327 |
0.545 |
|
| 2021 |
Kinloch NN, Ren Y, Alberto WDC, Dong W, Khadka P, Huang SH, Mota TM, Wilson A, Shahid A, Kirkby D, Harris M, Kovacs C, Benko E, Ostrowski MA, Del Rio Estrada PM, ... ... Lynch RM, et al. Author Correction: HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA). Nature Communications. 12: 2958. PMID 33986282 DOI: 10.1038/s41467-021-23515-z |
0.31 |
|
| 2021 |
Klatt NR, Broedlow C, Osborn JM, Gustin AT, Dross S, O'Connor MA, Coronado E, Barnette P, Hensley-McBain T, Zevin AS, Muir R, Roederer A, Wangari S, Iwayama N, Ahrens CY, ... ... Lynch RM, et al. Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques. Npj Vaccines. 6: 34. PMID 33707443 DOI: 10.1038/s41541-021-00298-4 |
0.385 |
|
| 2021 |
Kinloch NN, Ren Y, Conce Alberto WD, Dong W, Khadka P, Huang SH, Mota TM, Wilson A, Shahid A, Kirkby D, Harris M, Kovacs C, Benko E, Ostrowski MA, Del Rio Estrada PM, ... ... Lynch RM, et al. HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA). Nature Communications. 12: 165. PMID 33420062 DOI: 10.1038/s41467-020-20442-3 |
0.404 |
|
| 2020 |
Wilson A, Lynch RM. Embracing diversity: how can broadly neutralizing antibodies effectively target a diverse HIV-1 reservoir? Current Opinion in Pharmacology. 54: 173-178. PMID 33189993 DOI: 10.1016/j.coph.2020.10.004 |
0.463 |
|
| 2020 |
Ren Y, Korom M, Ward AR, Truong R, Chan D, Huang SH, Kovacs CC, Benko E, Safrit JT, Lee J, Garbán H, Lynch R, Jones RB. Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV. Journal of Virology. PMID 33115874 DOI: 10.1128/JVI.01808-20 |
0.483 |
|
| 2020 |
Powell AB, Ren Y, Korom M, Saunders D, Hanley PJ, Goldstein H, Nixon DF, Bollard CM, Lynch RM, Jones RB, Cruz CRY. Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV. Molecular Therapy. Methods & Clinical Development. 19: 78-88. PMID 33005704 DOI: 10.1016/J.Omtm.2020.08.015 |
0.507 |
|
| 2020 |
Cale EM, Bai H, Bose M, Messina MA, Colby D, Sanders-Buell E, Dearlove BL, Li Y, Engeman E, Silas D, O'Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, ... ... Lynch RM, et al. Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound. The Journal of Clinical Investigation. PMID 32182219 DOI: 10.1172/JCI134395 |
0.512 |
|
| 2019 |
Rawi R, Mall R, Shen CH, Farney SK, Shiakolas A, Zhou J, Bensmail H, Chun TW, Doria-Rose NA, Lynch RM, Mascola JR, Kwong PD, Chuang GY. Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates. Scientific Reports. 9: 14696. PMID 31604961 DOI: 10.1038/S41598-019-50635-W |
0.395 |
|
| 2019 |
Yu WH, Su D, Torabi J, Fennessey CM, Shiakolas A, Lynch R, Chun TW, Doria-Rose N, Alter G, Seaman MS, Keele BF, Lauffenburger DA, Julg B. Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir. Jci Insight. 4. PMID 31484826 DOI: 10.1172/Jci.Insight.130153 |
0.495 |
|
| 2019 |
Bar KJ, Coronado E, Hensley-McBain T, O'Connor MA, Osborn JM, Miller C, Gott TM, Wangari S, Iwayama N, Ahrens CY, Smedley J, Moats C, Lynch RM, Haddad EK, Haigwood NL, et al. SHIV.CH505 infection of rhesus macaques results in persistent viral replication and induces intestinal immunopathology. Journal of Virology. PMID 31217249 DOI: 10.1128/Jvi.00372-19 |
0.475 |
|
| 2019 |
Flerin NC, Bardhi A, Zheng JH, Korom M, Folkvord J, Kovacs C, Benko E, Truong R, Mota T, Connick E, Jones RB, Lynch RM, Goldstein H. Establishment of A Novel Humanized Mouse Model To Investigate Activation and Depletion of Patient-Derived HIV Latent Reservoirs. Journal of Virology. PMID 30626677 DOI: 10.1128/Jvi.02051-18 |
0.468 |
|
| 2018 |
Ren Y, Korom M, Truong R, Chan D, Huang SH, Kovacs CC, Benko E, Safrit JT, Lee J, Garbán H, Apps R, Goldstein H, Lynch RM, Jones RB. Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs. Journal of Virology. PMID 30209173 DOI: 10.1128/Jvi.00895-18 |
0.547 |
|
| 2018 |
Lynch RM, Mantus G, Encinales L, Pacheco N, Li G, Porras A, Mendoza AR, Peng J, Rengifo-Pardo M, Cruz MM, Harris E, Bethony JM, Simon GL, Chang AY. Augmented Zika and dengue neutralizing antibodies are associated with Guillain-Barré syndrome. The Journal of Infectious Diseases. PMID 30113672 DOI: 10.1093/Infdis/Jiy466 |
0.385 |
|
| 2018 |
González N, McKee K, Lynch RM, Georgiev IS, Jimenez L, Grau E, Yuste E, Kwong PD, Mascola JR, Alcamí J. Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors. Plos One. 13: e0193773. PMID 29558468 DOI: 10.1371/Journal.Pone.0193773 |
0.551 |
|
| 2017 |
Bhiman JN, Lynch RM. Broadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune System. Current Hiv/Aids Reports. PMID 28349376 DOI: 10.1007/s11904-017-0352-1 |
0.319 |
|
| 2017 |
de Bree GJ, Wheatley AK, Lynch RM, Prabhakaran M, Grijsen ML, Prins JM, Schmidt SD, Koup RA, Mascola JR, McDermott AB. Longitudinal dynamics of the HIV-specific B cell response during intermittent treatment of primary HIV infection. Plos One. 12: e0173577. PMID 28296911 DOI: 10.1371/Journal.Pone.0173577 |
0.559 |
|
| 2016 |
Bar KJ, Sneller MC, Harrison LJ, Justement JS, Overton ET, Petrone ME, Salantes DB, Seamon CA, Scheinfeld B, Kwan RW, Learn GH, Proschan MA, Kreider EF, Blazkova J, Bardsley M, ... ... Lynch RM, et al. Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption. The New England Journal of Medicine. 375: 2037-2050. PMID 27959728 DOI: 10.1056/Nejmoa1608243 |
0.507 |
|
| 2016 |
de Bree GJ, Lynch RM. B cells in HIV pathogenesis. Current Opinion in Infectious Diseases. 29: 23-30. PMID 26658653 DOI: 10.1097/Qco.0000000000000225 |
0.594 |
|
| 2015 |
Lynch RM, Boritz E, Coates EE, DeZure A, Madden P, Costner P, Enama ME, Plummer S, Holman L, Hendel CS, Gordon I, Casazza J, Conan-Cibotti M, Migueles SA, Tressler R, et al. Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection. Science Translational Medicine. 7: 319ra206. PMID 26702094 DOI: 10.1126/Scitranslmed.Aad5752 |
0.581 |
|
| 2015 |
Doria-Rose NA, Bhiman JN, Roark RS, Schramm CA, Gorman J, Chuang GY, Pancera M, Cale EM, Ernandes MJ, Louder MK, Asokan M, Bailer RT, Druz A, Fraschilla IR, Garrett NJ, ... ... Lynch RM, et al. A new member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency. Journal of Virology. PMID 26468542 DOI: 10.1128/Jvi.01791-15 |
0.533 |
|
| 2015 |
Ledgerwood JE, Coates EE, Yamshchikov G, Saunders JG, Holman L, Enama ME, DeZure A, Lynch R, Gordon I, Plummer S, Hendel CS, Pegu A, Conan-Cibotti M, Sitar S, Bailer RT, et al. Safety, Pharmacokinetics, and Neutralization of the Broadly Neutralizing HIV-1 Human Monoclonal Antibody VRC01 in Healthy Adults. Clinical and Experimental Immunology. PMID 26332605 DOI: 10.1111/Cei.12692 |
0.471 |
|
| 2015 |
Yamamoto T, Lynch RM, Gautam R, Matus-Nicodemos R, Schmidt SD, Boswell KL, Darko S, Wong P, Sheng Z, Petrovas C, McDermott AB, Seder RA, Keele BF, Shapiro L, Douek DC, et al. Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection. Science Translational Medicine. 7: 298ra120. PMID 26223303 DOI: 10.1126/Scitranslmed.Aab3964 |
0.58 |
|
| 2015 |
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, et al. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 161: 1280-92. PMID 26004070 DOI: 10.1016/J.Cell.2015.05.007 |
0.517 |
|
| 2015 |
Wu X, Zhang Z, Schramm CA, Joyce MG, Kwon YD, Zhou T, Sheng Z, Zhang B, O'Dell S, McKee K, Georgiev IS, Chuang GY, Longo NS, Lynch RM, Saunders KO, et al. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell. 161: 470-85. PMID 25865483 DOI: 10.1016/J.Cell.2015.03.004 |
0.578 |
|
| 2015 |
Francica JR, Sheng Z, Zhang Z, Nishimura Y, Shingai M, Ramesh A, Keele BF, Schmidt SD, Flynn BJ, Darko S, Lynch RM, Yamamoto T, Matus-Nicodemos R, Wolinsky D, et al. Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization. Nature Communications. 6: 6565. PMID 25858157 DOI: 10.1038/Ncomms7565 |
0.525 |
|
| 2015 |
Lynch RM, Wong P, Tran L, O'Dell S, Nason MC, Li Y, Wu X, Mascola JR. HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies. Journal of Virology. 89: 4201-13. PMID 25631091 DOI: 10.1128/Jvi.03608-14 |
0.593 |
|
| 2014 |
Gao F, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, et al. Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies. Cell. 158: 481-91. PMID 25065977 DOI: 10.1016/J.Cell.2014.06.022 |
0.58 |
|
| 2014 |
Bonsignori M, Wiehe K, Grimm SK, Lynch R, Yang G, Kozink DM, Perrin F, Cooper AJ, Hwang KK, Chen X, Liu M, McKee K, Parks RJ, Eudailey J, Wang M, et al. An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. The Journal of Clinical Investigation. 124: 1835-43. PMID 24614107 DOI: 10.1172/Jci73441 |
0.573 |
|
| 2014 |
Lynch RM, Yamamoto T, Wong P, Georgiev I, Matus-Nicodemos R, Schmidt S, Gautam R, Sheng Z, Shapiro L, Nishimura Y, Martin MA, Mascola JR, Koup RA. Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5145.Abstract |
0.608 |
|
| 2013 |
Lynch RM, Yamamoto T, McDermott AB. HIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infection. Current Opinion in Hiv and Aids. 8: 288-94. PMID 23666390 DOI: 10.1097/Coh.0B013E328361Cfe8 |
0.489 |
|
| 2013 |
Liao HX, Lynch R, Zhou T, Gao F, Munir Alam S, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L, Mullikin JC, Gnanakaran S, Hraber P, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature. 496: 469-476. PMID 23552890 DOI: 10.1038/Nature12053 |
0.606 |
|
| 2012 |
Lynch RM, Tran L, Louder MK, Schmidt SD, Cohen M, Dersimonian R, Euler Z, Gray ES, Abdool Karim S, Kirchherr J, Montefiori DC, Sibeko S, Soderberg K, Tomaras G, et al. The development of CD4 binding site antibodies during HIV-1 infection. Journal of Virology. 86: 7588-95. PMID 22573869 DOI: 10.1128/Jvi.00734-12 |
0.617 |
|
| 2012 |
Zhou T, Moquin S, Lynch R, Wu X, Zhu J, Yang Y, Zhang B, Mascola J, Kwong P. Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120 Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P57 |
0.537 |
|
| 2011 |
Klatt NR, Vinton CL, Lynch RM, Canary LA, Ho J, Darrah PA, Estes JD, Seder RA, Moir SL, Brenchley JM. SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination. Blood. 118: 5803-12. PMID 21960586 DOI: 10.1182/Blood-2011-07-365874 |
0.449 |
|
| 2011 |
Lynch RM, Rong R, Boliar S, Sethi A, Li B, Mulenga J, Allen S, Robinson JE, Gnanakaran S, Derdeyn CA. The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. Journal of Virology. 85: 905-15. PMID 20980495 DOI: 10.1128/Jvi.02006-10 |
0.684 |
|
| 2010 |
Lynch RM, Rong R, Li B, Shen T, Honnen W, Mulenga J, Allen S, Pinter A, Gnanakaran S, Derdeyn CA. Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection. Virology. 404: 59-70. PMID 20494390 DOI: 10.1016/J.Virol.2010.04.010 |
0.654 |
|
| 2010 |
Alexander M, Lynch R, Mulenga J, Allen S, Derdeyn CA, Hunter E. Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry. Journal of Virology. 84: 4100-4. PMID 20147398 DOI: 10.1128/Jvi.02068-09 |
0.638 |
|
| 2009 |
Rong R, Li B, Lynch RM, Haaland RE, Murphy MK, Mulenga J, Allen SA, Pinter A, Shaw GM, Hunter E, Robinson JE, Gnanakaran S, Derdeyn CA. Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. Plos Pathogens. 5: e1000594. PMID 19763269 DOI: 10.1371/Journal.Ppat.1000594 |
0.698 |
|
| 2009 |
Lynch RM, Shen T, Gnanakaran S, Derdeyn CA. Appreciating HIV type 1 diversity: subtype differences in Env. Aids Research and Human Retroviruses. 25: 237-48. PMID 19327047 DOI: 10.1089/Aid.2008.0219 |
0.674 |
|
| 2009 |
Rong R, Li B, Lynch RM, Mulenga J, Allen S, Hunter E, Blackwell JL, Derdeyn CA. 107 Escape from Neutralizing Antibody in Early Subtype C HIV-1 Infection Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351064.57428.B1 |
0.703 |
|
| 2008 |
Do Y, Park CG, Kang YS, Park SH, Lynch RM, Lee H, Powell BS, Steinman RM. Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205/CD205-positive mouse dendritic cells. European Journal of Immunology. 38: 20-9. PMID 18081041 DOI: 10.1002/Eji.200737799 |
0.366 |
|
| 2007 |
Bostik P, Stephenson ST, Lynch RM, Cardona A, Ansari AA. Maintenance of CD4+ T cell TCR Vbeta repertoire heterogeneity is characteristic of apathogenic SIV infection in non-human primate model of AIDS. Virology. 369: 324-8. PMID 17889219 DOI: 10.1016/J.Virol.2007.07.019 |
0.355 |
|
| 2006 |
Kang YS, Do Y, Lee HK, Park SH, Cheong C, Lynch RM, Loeffler JM, Steinman RM, Park CG. A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. Cell. 125: 47-58. PMID 16615889 DOI: 10.1016/J.Cell.2006.01.046 |
0.323 |
|
| 2002 |
Kozlowski PA, Williams SB, Lynch RM, Flanigan TP, Patterson RR, Cu-Uvin S, Neutra MR. Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle. Journal of Immunology (Baltimore, Md. : 1950). 169: 566-74. PMID 12077289 DOI: 10.4049/Jimmunol.169.1.566 |
0.335 |
|
| 2000 |
Kozlowski PA, Lynch RM, Patterson RR, Cu-Uvin S, Flanigan TP, Neutra MR. Modified wick method using weck-cel sponges for collection of human rectal secretions and analysis of mucosal HIV antibody Journal of Acquired Immune Deficiency Syndromes. 24: 297-309. PMID 11015145 DOI: 10.1097/00126334-200008010-00001 |
0.479 |
|
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