| Year |
Citation |
Score |
| 2024 |
Varco-Merth B, Chaunzwa M, Duell DM, Marenco A, Goodwin W, Dannay R, Nekorchuk M, Shao D, Busman-Sahay K, Fennessey CM, Silipino L, Hull M, Bosche WJ, Fast R, Oswald K, ... ... Keele BF, et al. Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence. Plos Pathogens. 20: e1012496. PMID 39173097 DOI: 10.1371/journal.ppat.1012496 |
0.675 |
|
| 2024 |
Pitchai FNN, Tanner EJ, Khetan N, Vasen G, Levrel C, Kumar AJ, Pandey S, Ordonez T, Barnette P, Spencer D, Jung SY, Glazier J, Thompson C, Harvey-Vera A, Son HI, ... ... Keele BF, et al. Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates. Science (New York, N.Y.). 385: eadn5866. PMID 39116226 DOI: 10.1126/science.adn5866 |
0.664 |
|
| 2024 |
Sui Y, Meyer TJ, Fennessey CM, Keele BF, Dadkhah K, Ma C, LaBranche CC, Breed MW, Kramer JA, Li J, Howe SE, Ferrari G, Williams LD, Cam M, Kelly MC, et al. Innate protection against intrarectal SIV acquisition by a live SHIV vaccine. Jci Insight. 9. PMID 38912579 DOI: 10.1172/jci.insight.175800 |
0.332 |
|
| 2024 |
Klenchin VA, Clark NM, Keles NK, Capuano S, Mason R, Gao G, Broman A, Kose E, Immonen TT, Fennessey CM, Keele BF, Lifson JD, Roederer M, Gardner MR, Evans DT. Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy. Biorxiv : the Preprint Server For Biology. PMID 38895320 DOI: 10.1101/2024.05.30.593694 |
0.335 |
|
| 2024 |
Simpson J, Starke CE, Ortiz AM, Ransier A, Darko S, Llewellyn-Lacey S, Fennessey CM, Keele BF, Douek DC, Price DA, Brenchley JM. Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of Simian immunodeficiency virus. Jci Insight. PMID 38885329 DOI: 10.1172/jci.insight.174168 |
0.399 |
|
| 2024 |
Immonen TT, Fennessey CM, Lipkey L, Newman L, Macairan A, Bosche M, Waltz N, Del Prete GQ, Lifson JD, Keele BF. No evidence for ongoing replication on ART in SIV-infected macaques. Nature Communications. 15: 5093. PMID 38877003 DOI: 10.1038/s41467-024-49369-9 |
0.4 |
|
| 2024 |
Keele BF, Okoye AA, Fennessey CM, Varco-Merth B, Immonen TT, Kose E, Conchas A, Pinkevych M, Lipkey L, Newman L, Macairan A, Bosche M, Bosche WJ, Berkemeier B, Fast R, et al. Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir. Plos Pathogens. 20: e1012135. PMID 38593120 DOI: 10.1371/journal.ppat.1012135 |
0.385 |
|
| 2024 |
Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, et al. TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo. Nature Communications. 15: 1348. PMID 38355731 DOI: 10.1038/s41467-024-45555-x |
0.418 |
|
| 2024 |
Grunst MW, Gil HM, Grandea AG, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S, Fennessey CM, Friedrich TC, ... ... Keele BF, et al. Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge. Plos Pathogens. 20: e1011819. PMID 38252675 DOI: 10.1371/journal.ppat.1011819 |
0.358 |
|
| 2023 |
Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Lymphoid tissues contribute to plasma viral clonotypes early after antiretroviral therapy interruption in SIV-infected rhesus macaques. Science Translational Medicine. 15: eadi9867. PMID 38091409 DOI: 10.1126/scitranslmed.adi9867 |
0.411 |
|
| 2023 |
Docken SS, McCormick K, Pampena MB, Samer S, Lindemuth E, Pinkevych M, Viox EG, Wu Y, Schlub TE, Cromer D, Keele BF, Paiardini M, Betts MR, Bar KJ, Davenport MP. Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency. Plos Pathogens. 19: e1011755. PMID 38032851 DOI: 10.1371/journal.ppat.1011755 |
0.452 |
|
| 2023 |
Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, et al. TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs . Biorxiv : the Preprint Server For Biology. PMID 38014094 DOI: 10.1101/2023.09.05.556422 |
0.42 |
|
| 2023 |
Pinkevych M, Docken SS, Okoye AA, Fennessey CM, Del Prete GQ, Pino M, Harper JL, Betts MR, Paiardini M, Keele BF, Davenport MP. Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication. Plos Pathogens. 19: e1011660. PMID 37801446 DOI: 10.1371/journal.ppat.1011660 |
0.469 |
|
| 2023 |
Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection. Plos Pathogens. 19: e1011676. PMID 37747933 DOI: 10.1371/journal.ppat.1011676 |
0.574 |
|
| 2023 |
Smedley J, Turkbey B, Bernardo ML, Del Prete GQ, Estes JD, Griffiths GL, Kobayashi H, Choyke PL, Lifson JD, Keele BF. Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission. Plos One. 18: e0288566. PMID 37418480 DOI: 10.1371/journal.pone.0288566 |
0.563 |
|
| 2023 |
Bauer A, Lindemuth E, Marino FE, Krause R, Joy J, Docken SS, Mallick S, McCormick K, Holt C, Georgiev I, Felber B, Keele BF, Veazey R, Davenport MP, Li H, et al. Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques. Plos Pathogens. 19: e1011059. PMID 37399208 DOI: 10.1371/journal.ppat.1011059 |
0.464 |
|
| 2023 |
Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Lymphoid tissues contribute to viral clonotypes present in plasma at early post-ATI in SIV-infected rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37398418 DOI: 10.1101/2023.05.30.542512 |
0.435 |
|
| 2023 |
Lisco A, Lange C, Manion M, Kuriakose S, Dewar R, Gorelick RJ, Huik K, Yu Q, Hammoud DA, Smith BR, Muranski P, Rehm C, Sherman BT, Sykes C, Lindo N, ... ... Keele BF, et al. Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV. Nature Medicine. PMID 37322122 DOI: 10.1038/s41591-023-02387-4 |
0.438 |
|
| 2023 |
Sanders-Beer BE, Archin NM, Brumme ZL, Busch M, Deleage C, O'Doherty U, Hughes SH, Jerome K, Jones RB, Karn J, Kearney MF, Keele B, Kulpa D, Laird G, Li JZ, et al. Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary. Aids Research and Human Retroviruses. PMID 37126090 DOI: 10.1089/AID.2022.0188 |
0.408 |
|
| 2023 |
Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Keele BF, et al. Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 19: e1011343. PMID 37075022 DOI: 10.1371/journal.ppat.1011343 |
0.467 |
|
| 2023 |
Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques. Biorxiv : the Preprint Server For Biology. PMID 36909458 DOI: 10.1101/2023.03.01.530655 |
0.566 |
|
| 2023 |
Statzu M, Jin W, Fray EJ, Wong AKH, Kumar MR, Ferrer E, Docken SS, Pinkevych M, McBrien JB, Fennessey CM, Keele BF, Liang S, Harper JL, Mutascio S, Franchitti L, et al. CD8 lymphocytes do not impact SIV reservoir establishment under ART. Nature Microbiology. PMID 36690860 DOI: 10.1038/s41564-022-01311-9 |
0.52 |
|
| 2022 |
Woolley G, Mosher M, Kroll K, Jones R, Hueber B, Sugawara S, Manickam C, Terry K, Varner V, Lifton M, Ram D, Fennessey CM, Keele BF, Reeves RK. Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. Journal of Virology. e0151922. PMID 36511699 DOI: 10.1128/jvi.01519-22 |
0.451 |
|
| 2022 |
Gorman J, Wang C, Mason RD, Nazzari AF, Welles HC, Zhou T, Bess JW, Bylund T, Lee M, Tsybovsky Y, Verardi R, Wang S, Yang Y, Zhang B, Rawi R, ... Keele BF, et al. Cryo-EM structures of prefusion SIV envelope trimer. Nature Structural & Molecular Biology. PMID 36344847 DOI: 10.1038/s41594-022-00852-1 |
0.321 |
|
| 2022 |
Rawson JMO, Nikolaitchik OA, Shakya S, Keele BF, Pathak VK, Hu WS. Transcription Start Site Heterogeneity and Preferential Packaging of Specific Full-Length RNA Species Are Conserved Features of Primate Lentiviruses. Microbiology Spectrum. e0105322. PMID 35736240 DOI: 10.1128/spectrum.01053-22 |
0.414 |
|
| 2022 |
Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, ... ... Keele BF, et al. A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. Plos Pathogens. 18: e1010507. PMID 35714165 DOI: 10.1371/journal.ppat.1010507 |
0.337 |
|
| 2022 |
Pegu A, Xu L, DeMouth ME, Fabozzi G, March K, Almasri CG, Cully MD, Wang K, Yang ES, Dias J, Fennessey CM, Hataye J, Wei RR, Rao E, Casazza JP, ... ... Keele BF, et al. Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys. Cell Reports. 38: 110199. PMID 34986348 DOI: 10.1016/j.celrep.2021.110199 |
0.506 |
|
| 2021 |
Moriarty RV, Golfinos AE, Gellerup DD, Schweigert H, Mathiaparanam J, Balgeman AJ, Weiler AM, Friedrich TC, Keele BF, Davenport MP, Venturi V, O'Connor SL. The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth. Plos One. 16: e0260010. PMID 34855793 DOI: 10.1371/journal.pone.0260010 |
0.463 |
|
| 2021 |
Frank I, Cigoli M, Arif MS, Fahlberg MD, Maldonado S, Calenda G, Pegu A, Yang ES, Rawi R, Chuang GY, Geng H, Liu C, Zhou T, Kwong PD, Arthos J, ... ... Keele BF, et al. Blocking αβ integrin delays viral rebound in SHIV-infected macaques treated with anti-HIV broadly neutralizing antibodies. Science Translational Medicine. 13. PMID 34408080 DOI: 10.1126/scitranslmed.abf7201 |
0.414 |
|
| 2021 |
Immonen TT, Fennessey CM, Lipkey L, Thorpe A, Del Prete GQ, Lifson JD, Davenport MP, Keele BF. Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir. Plos Pathogens. 17: e1009686. PMID 34143853 DOI: 10.1371/journal.ppat.1009686 |
0.435 |
|
| 2021 |
Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Keele BF, et al. Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 17: e1009565. PMID 33970966 DOI: 10.1371/journal.ppat.1009565 |
0.581 |
|
| 2021 |
Kleinman A, Sivanandham R, Sette P, Brocca-Cofano E, McAndrews C, Keele B, Pandrea I, Apetrei C. Lack of Specific Regulatory T-Cell Depletion and Cytoreduction Associated with Extensive Toxicity after Administration of Low and High Doses of Cyclophosphamide. Aids Research and Human Retroviruses. PMID 33957772 DOI: 10.1089/AID.2021.0036 |
0.401 |
|
| 2021 |
Boltz VF, Ceriani C, Rausch JW, Shao W, Bale MJ, Keele BF, Hoh R, Milush JM, Deeks SG, Maldarelli F, Kearney MF, Coffin JM. CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART. Viruses. 13. PMID 33946976 DOI: 10.3390/v13050799 |
0.386 |
|
| 2021 |
Li H, Wang S, Lee FH, Roark RS, Murphy AI, Smith J, Zhao C, Rando J, Chohan N, Ding Y, Kim E, Lindemuth E, Bar KJ, Pandrea I, Apetrei C, ... Keele BF, et al. New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure. Journal of Virology. PMID 33658341 DOI: 10.1128/JVI.00071-21 |
0.576 |
|
| 2021 |
Okoye AA, Duell DD, Fukazawa Y, Varco-Merth B, Marenco A, Behrens H, Chaunzwa TM, Selseth AN, Gilbride RM, Shao J, Edlefsen PT, Geleziunas R, Pinkevych M, Davenport MP, Busman-Sahay K, ... ... Keele BF, et al. CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification. The Journal of Clinical Investigation. PMID 33630764 DOI: 10.1172/JCI141677 |
0.626 |
|
| 2021 |
Swanstrom AE, Immonen TT, Oswald K, Pyle C, Thomas JA, Bosche WJ, Silipino L, Hull M, Newman L, Coalter V, Wiles A, Wiles R, Kiser J, Morcock DR, Shoemaker R, ... ... Keele BF, et al. Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy. The Journal of Clinical Investigation. PMID 33465055 DOI: 10.1172/JCI142421 |
0.683 |
|
| 2020 |
Wei Q, Hargett AA, Knoppova B, Duverger A, Rawi R, Shen CH, Farney SK, Hall S, Brown R, Keele BF, Heath SL, Saag MS, Kutsch O, Chuang GY, Kwong PD, et al. Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies. Iscience. 23: 101711. PMID 33205023 DOI: 10.1016/j.isci.2020.101711 |
0.349 |
|
| 2020 |
Liu PT, Keele BF, Abbink P, Mercado NB, Liu J, Bondzie EA, Chandrashekar A, Borducchi EN, Hesselgesser J, Mish M, Chin G, Bekerman E, Geleziunas R, Barouch DH. Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation. Nature Communications. 11: 5412. PMID 33110078 DOI: 10.1038/s41467-020-19254-2 |
0.467 |
|
| 2020 |
Halvas EK, Joseph KW, Brandt LD, Guo S, Sobolewski MD, Jacobs JL, Tumiotto C, Bui JK, Cyktor JC, Keele BF, Morse GD, Bale MJ, Shao W, Kearney MF, Coffin JM, et al. HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus. The Journal of Clinical Investigation. PMID 33016926 DOI: 10.1172/JCI138099 |
0.438 |
|
| 2020 |
Wu Y, Pinkevych M, Xu Z, Keele BF, Davenport MP, Cromer D. Impact of fluctuation in frequency of human immunodeficiency virus/simian immunodeficiency virus reactivation during antiretroviral therapy interruption. Proceedings. Biological Sciences. 287: 20200354. PMID 32811309 DOI: 10.1098/rspb.2020.0354 |
0.527 |
|
| 2020 |
Rust BJ, Kean LS, Colonna L, Brandenstein K, Poole NH, Obenza W, Enstrom MR, Maldini CR, Ellis GI, Fennessey CM, Huang ML, Keele BF, Jerome K, Riley JL, Kiem HP, et al. Robust Expansion of HIV CAR T Cells Following Antigen Boosting in ART-Suppressed Nonhuman Primates. Blood. PMID 32614969 DOI: 10.1182/Blood.2020006372 |
0.504 |
|
| 2020 |
Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M, Keele BF, Estes JD, Apetrei C, et al. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333. PMID 32119719 DOI: 10.1371/Journal.Ppat.1008333 |
0.662 |
|
| 2020 |
Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, ... ... Keele BF, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. PMID 31969707 DOI: 10.1038/S41586-020-1951-3 |
0.529 |
|
| 2020 |
Melody K, Roy CN, Kline C, Cottrell ML, Evans D, Shutt K, Pennings PS, Keele BF, Bility M, Kashuba ADM, Ambrose Z. Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice. Journal of Virology. PMID 31969438 DOI: 10.1128/Jvi.01912-19 |
0.434 |
|
| 2019 |
Immonen TT, Camus C, Reid C, Fennessey CM, Del Prete GQ, Davenport MP, Lifson JD, Keele BF. Genetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escape. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843933 DOI: 10.1073/pnas.1914967117 |
0.327 |
|
| 2019 |
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, ... ... Keele BF, et al. Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31776247 DOI: 10.1073/Pnas.1910334116 |
0.404 |
|
| 2019 |
Hataye JM, Casazza JP, Best K, Liang CJ, Immonen TT, Ambrozak DR, Darko S, Henry AR, Laboune F, Maldarelli F, Douek DC, Hengartner NW, Yamamoto T, Keele BF, Perelson AS, et al. Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread. Cell Host & Microbe. PMID 31761718 DOI: 10.1016/j.chom.2019.10.006 |
0.559 |
|
| 2019 |
Pinkevych M, Fennessey CM, Cromer D, Reid C, Trubey CM, Lifson JD, Keele BF, Davenport MP. Predictors of SIV recrudescence following antiretroviral treatment interruption. Elife. 8. PMID 31650954 DOI: 10.7554/eLife.49022 |
0.418 |
|
| 2019 |
Musick A, Spindler J, Boritz E, Pérez L, Crespo-Vélez D, Patro SC, Sobolewski MD, Bale MJ, Reid C, Keele BF, Capoferri A, Shao W, Wiegand A, Simonetti FR, Mellors JW, et al. HIV Infected T Cells Can Proliferate Without Inducing Expression of the Integrated Provirus. Frontiers in Microbiology. 10: 2204. PMID 31632364 DOI: 10.3389/Fmicb.2019.02204 |
0.547 |
|
| 2019 |
Long S, Fennessey CM, Newman L, Reid C, O'Brien SP, Li Y, Del Prete GQ, Lifson JD, Gorelick RJ, Keele BF. Evaluating the intactness of persistent viral genomes in SIV-infected rhesus macaques initiating antiretroviral therapy within one year of infection. Journal of Virology. PMID 31597776 DOI: 10.1128/JVI.01308-19 |
0.418 |
|
| 2019 |
Khanal S, Fennessey CM, O'Brien SP, Thorpe A, Reid C, Immonen TT, Smith R, Bess JW, Swanstrom AE, Del Prete GQ, Davenport MP, Okoye AA, Picker LJ, Lifson JD, Keele BF. validation of the viral barcoding of SIVmac239 and the development of new barcoded SIV and subtype B and C SHIVs. Journal of Virology. PMID 31597757 DOI: 10.1128/JVI.01420-19 |
0.44 |
|
| 2019 |
Redd AD, Doria-Rose NA, Weiner JA, Nason M, Seivers M, Schmidt SD, Laeyendecker O, Martens C, Bruno D, Keele BF, Raju N, Georgiev IS, Lamers SL, Astemborski J, Kirk GD, et al. Longitudinal antibody responses in people who inject drugs infected with similar HIV strains. The Journal of Infectious Diseases. PMID 31581292 DOI: 10.1093/Infdis/Jiz503 |
0.423 |
|
| 2019 |
Abbink P, Mercado NB, Nkolola JP, Peterson RL, Tuyishime H, McMahan K, Moseley ET, Borducchi EN, Chandrashekar A, Bondzie EA, Agarwal A, Belli AJ, Reimann KA, Keele BF, Geleziunas R, et al. Lack of therapeutic efficacy of an antibody to αβ in SIVmac251-infected rhesus macaques. Science (New York, N.Y.). 365: 1029-1033. PMID 31488689 DOI: 10.1126/science.aaw8562 |
0.493 |
|
| 2019 |
Di Mascio M, Lifson JD, Srinivasula S, Kim I, DeGrange P, Keele BF, Belli AJ, Reimann KA, Wang Y, Proschan M, Lane HC, Fauci AS. Evaluation of an antibody to αβ in the control of SIVmac239- infection. Science (New York, N.Y.). 365: 1025-1029. PMID 31488688 DOI: 10.1126/Science.Aav6695 |
0.401 |
|
| 2019 |
Yu WH, Su D, Torabi J, Fennessey CM, Shiakolas A, Lynch R, Chun TW, Doria-Rose N, Alter G, Seaman MS, Keele BF, Lauffenburger DA, Julg B. Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir. Jci Insight. 4. PMID 31484826 DOI: 10.1172/Jci.Insight.130153 |
0.459 |
|
| 2019 |
Deleage C, Immonen TT, Fennessey CM, Reynaldi A, Reid C, Newman L, Lipkey L, Schlub TE, Camus C, O'Brien S, Smedley J, Conway JM, Del Prete GQ, Davenport MP, Lifson JD, ... ... Keele BF, et al. Defining early SIV replication and dissemination dynamics following vaginal transmission. Science Advances. 5: eaav7116. PMID 31149634 DOI: 10.1126/Sciadv.Aav7116 |
0.647 |
|
| 2019 |
Schmidt F, Keele BF, Del Prete GQ, Voronin D, Fennessey CM, Soll S, Kane M, Raymond A, Gifford RJ, KewalRamani V, Lifson JD, Bieniasz PD, Hatziioannou T. Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host. Proceedings of the National Academy of Sciences of the United States of America. PMID 31048506 DOI: 10.1073/Pnas.1818059116 |
0.474 |
|
| 2019 |
Fennessey CM, Camus C, Immonen TT, Reid C, Maldarelli F, Lifson JD, Keele BF. Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo. Retrovirology. 16: 11. PMID 30947720 DOI: 10.1186/s12977-019-0473-2 |
0.308 |
|
| 2019 |
O'Brien SP, Swanstrom AE, Pegu A, Ko SY, Immonen TT, Del Prete GQ, Fennessey CM, Gorman J, Foulds KE, Schmidt SD, Doria-Rose N, Williamson C, Hatziioannou T, Bieniasz PD, Li H, ... ... Keele BF, et al. Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes. Plos Pathogens. 15: e1007632. PMID 30943274 DOI: 10.1371/journal.ppat.1007632 |
0.484 |
|
| 2019 |
Martinez-Navio JM, Fuchs SP, Pantry SN, Lauer WA, Duggan NN, Keele BF, Rakasz EG, Gao G, Lifson JD, Desrosiers RC. Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression. Immunity. PMID 30850342 DOI: 10.1016/J.Immuni.2019.02.005 |
0.391 |
|
| 2019 |
Patro SC, Wu X, Guo S, Bale MJ, Wiegand A, Spindler J, Fennessey CM, Halvas EK, Keele BF, Hughes SH, Mellors JW, Coffin JM, Rausch JW, Kearney MF. A9 A method to obtain full-length HIV proviral sequences and their sites of integration Virus Evolution. 5. DOI: 10.1093/Ve/Vez002.008 |
0.368 |
|
| 2018 |
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| 2014 |
Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Keele BF, et al. Erratum: Corrigendum: Immune clearance of highly pathogenic SIV infection Nature. 514: 654-654. DOI: 10.1038/Nature13840 |
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Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA. A single amino acid mutation in the envelope cytoplasmic tail restores the ability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells. Journal of Virology. 87: 13048-52. PMID 24027336 DOI: 10.1128/Jvi.02126-13 |
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Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Keele BF, et al. Immune clearance of highly pathogenic SIV infection. Nature. 502: 100-4. PMID 24025770 DOI: 10.1038/Nature12519 |
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Fennessey CM, Keele BF. Using nonhuman primates to model HIV transmission. Current Opinion in Hiv and Aids. 8: 280-7. PMID 23666391 DOI: 10.1097/COH.0b013e328361cfff |
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Lopker M, Easlick J, Sterrett S, Decker JM, Barbian H, Learn G, Keele BF, Robinson JE, Li H, Hahn BH, Shaw GM, Bar KJ. Heterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock. Journal of Virology. 87: 5477-92. PMID 23468494 DOI: 10.1128/Jvi.03419-12 |
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| 2013 |
Del Prete GQ, Scarlotta M, Newman L, Reid C, Parodi LM, Roser JD, Oswald K, Marx PA, Miller CJ, Desrosiers RC, Barouch DH, Pal R, Piatak M, Chertova E, Giavedoni LD, ... ... Keele BF, et al. Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies. Journal of Virology. 87: 4584-95. PMID 23408608 DOI: 10.1128/Jvi.03507-12 |
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| 2013 |
Vaccari M, Keele BF, Bosinger SE, Doster MN, Ma ZM, Pollara J, Hryniewicz A, Ferrari G, Guan Y, Forthal DN, Venzon D, Fenizia C, Morgan T, Montefiori D, Lifson JD, et al. Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure. Journal of Virology. 87: 3538-48. PMID 23325681 DOI: 10.1128/Jvi.02863-12 |
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| 2013 |
Pegu P, Vaccari M, Gordon S, Keele BF, Doster M, Guan Y, Ferrari G, Pal R, Ferrari MG, Whitney S, Hudacik L, Billings E, Rao M, Montefiori D, Tomaras G, et al. Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial. Journal of Virology. 87: 1708-19. PMID 23175374 DOI: 10.1128/Jvi.02544-12 |
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| 2013 |
Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M, Lifson JD, ... Keele BF, et al. Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression. Journal of Virology. 87: 1528-43. PMID 23152518 DOI: 10.1128/Jvi.01928-12 |
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| 2013 |
Baalwa J, Wang S, Parrish NF, Decker JM, Keele BF, Learn GH, Yue L, Ruzagira E, Ssemwanga D, Kamali A, Amornkul PN, Price MA, Kappes JC, Karita E, Kaleebu P, et al. Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. Virology. 436: 33-48. PMID 23123038 DOI: 10.1016/J.Virol.2012.10.009 |
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| 2012 |
Li Y, Ndjango JB, Learn GH, Ramirez MA, Keele BF, Bibollet-Ruche F, Liu W, Easlick JL, Decker JM, Rudicell RS, Inogwabini BI, Ahuka-Mundeke S, Leendertz FH, Reynolds V, Muller MN, et al. Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir. Journal of Virology. 86: 10776-91. PMID 22837215 DOI: 10.1128/Jvi.01498-12 |
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Bar KJ, Tsao CY, Iyer SS, Decker JM, Yang Y, Bonsignori M, Chen X, Hwang KK, Montefiori DC, Liao HX, Hraber P, Fischer W, Li H, Wang S, Sterrett S, ... Keele BF, et al. Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. Plos Pathogens. 8: e1002721. PMID 22693447 DOI: 10.1371/Journal.Ppat.1002721 |
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| 2012 |
Gautam R, Nishimura Y, Lee WR, Donau O, Buckler-White A, Shingai M, Sadjadpour R, Schmidt SD, LaBranche CC, Keele BF, Montefiori D, Mascola JR, Martin MA. Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies. Journal of Virology. 86: 8516-26. PMID 22647691 DOI: 10.1128/Jvi.00644-12 |
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Bibollet-Ruche F, Heigele A, Keele BF, Easlick JL, Decker JM, Takehisa J, Learn G, Sharp PM, Hahn BH, Kirchhoff F. Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation. The Journal of Clinical Investigation. 122: 1644-52. PMID 22505456 DOI: 10.1172/Jci61429 |
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Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, Shaw GM, Wyatt RT, Mascola JR. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. Journal of Virology. 86: 5844-56. PMID 22419808 DOI: 10.1128/Jvi.07139-11 |
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Xiao P, Patterson LJ, Kuate S, Brocca-Cofano E, Thomas MA, Venzon D, Zhao J, DiPasquale J, Fenizia C, Lee EM, Kalisz I, Kalyanaraman VS, Pal R, Montefiori D, Keele BF, et al. Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge. Journal of Virology. 86: 4644-57. PMID 22345466 DOI: 10.1128/JVI.06812-11 |
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| 2012 |
Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW, Nagashima K, Keele BF, et al. Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques. Journal of Virology. 86: 3152-66. PMID 22238316 DOI: 10.1128/Jvi.06886-11 |
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Sharma UK, Schito M, Welte A, Rousseau C, Fitzgibbon J, Keele B, Shapiro S, McMichael A, Burns DN. Workshop summary: Novel biomarkers for HIV incidence assay development. Aids Research and Human Retroviruses. 28: 532-9. PMID 22206265 DOI: 10.1089/AID.2011.0332 |
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Ochsenbauer C, Edmonds TG, Ding H, Keele BF, Decker J, Salazar MG, Salazar-Gonzalez JF, Shattock R, Haynes BF, Shaw GM, Hahn BH, Kappes JC. Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages. Journal of Virology. 86: 2715-28. PMID 22190722 DOI: 10.1128/Jvi.06157-11 |
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Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Corrigendum to "Modeling sequence evolution in acute HIV-1 infection" [J. Theor. Biol. 261 (2009) 341-360] Journal of Theoretical Biology. 297: 187. DOI: 10.1016/J.Jtbi.2011.12.010 |
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| 2011 |
Terio KA, Kinsel MJ, Raphael J, Mlengeya T, Lipende I, Kirchhoff CA, Gilagiza B, Wilson ML, Kamenya S, Estes JD, Keele BF, Rudicell RS, Liu W, Patton S, Collins A, et al. Pathologic lesions in chimpanzees (Pan trogylodytes schweinfurthii) from Gombe National Park, Tanzania, 2004-2010. Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 42: 597-607. PMID 22204054 DOI: 10.1638/2010-0237.1 |
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Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/Journal.Ppat.1002209 |
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| 2011 |
Fenizia C, Keele BF, Nichols D, Cornara S, Binello N, Vaccari M, Pegu P, Robert-Guroff M, Ma ZM, Miller CJ, Venzon D, Hirsch V, Franchini G. TRIM5α does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposure. Journal of Virology. 85: 12399-409. PMID 21917950 DOI: 10.1128/Jvi.05707-11 |
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Asmal M, Hellmann I, Liu W, Keele BF, Perelson AS, Bhattacharya T, Gnanakaran S, Daniels M, Haynes BF, Korber BT, Hahn BH, Shaw GM, Letvin NL. A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity. Plos One. 6: e23673. PMID 21876761 DOI: 10.1371/Journal.Pone.0023673 |
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| 2011 |
Pandrea I, Gaufin T, Gautam R, Kristoff J, Mandell D, Montefiori D, Keele BF, Ribeiro RM, Veazey RS, Apetrei C. Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion. Plos Pathogens. 7: e1002170. PMID 21829366 DOI: 10.1371/Journal.Ppat.1002170 |
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| 2011 |
Ma ZM, Keele BF, Qureshi H, Stone M, Desilva V, Fritts L, Lifson JD, Miller CJ. SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasma. Aids Research and Human Retroviruses. 27: 1259-69. PMID 21732792 DOI: 10.1089/Aid.2011.0090 |
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Gay C, Dibben O, Anderson JA, Stacey A, Mayo AJ, Norris PJ, Kuruc JD, Salazar-Gonzalez JF, Li H, Keele BF, Hicks C, Margolis D, Ferrari G, Haynes B, Swanstrom R, et al. Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy. Plos One. 6: e19617. PMID 21573003 DOI: 10.1371/Journal.Pone.0019617 |
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Keele BF, Estes JD. Barriers to mucosal transmission of immunodeficiency viruses. Blood. 118: 839-46. PMID 21555745 DOI: 10.1182/Blood-2010-12-325860 |
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| 2010 |
Rudicell RS, Holland Jones J, Wroblewski EE, Learn GH, Li Y, Robertson JD, Greengrass E, Grossmann F, Kamenya S, Pintea L, Mjungu DC, Lonsdorf EV, Mosser A, Lehman C, Collins DA, ... Keele BF, et al. Impact of simian immunodeficiency virus infection on chimpanzee population dynamics. Plos Pathogens. 6: e1001116. PMID 20886099 DOI: 10.1371/Journal.Ppat.1001116 |
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Fischer W, Ganusov VV, Giorgi EE, Hraber PT, Keele BF, Leitner T, Han CS, Gleasner CD, Green L, Lo CC, Nag A, Wallstrom TC, Wang S, McMichael AJ, Haynes BF, et al. Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. Plos One. 5: e12303. PMID 20808830 DOI: 10.1371/Journal.Pone.0012303 |
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Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/Jvi.01155-10 |
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Keele BF. Identifying and characterizing recently transmitted viruses. Current Opinion in Hiv and Aids. 5: 327-34. PMID 20543609 DOI: 10.1097/COH.0b013e32833a0b9b |
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Li H, Bar KJ, Wang S, Decker JM, Chen Y, Sun C, Salazar-Gonzalez JF, Salazar MG, Learn GH, Morgan CJ, Schumacher JE, Hraber P, Giorgi EE, Bhattacharya T, Korber BT, ... ... Keele BF, et al. High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. Plos Pathogens. 6: e1000890. PMID 20485520 DOI: 10.1371/Journal.Ppat.1000890 |
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Stone M, Keele BF, Ma ZM, Bailes E, Dutra J, Hahn BH, Shaw GM, Miller CJ. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251. Journal of Virology. 84: 7083-95. PMID 20463069 DOI: 10.1128/Jvi.00481-10 |
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Bar KJ, Li H, Chamberland A, Tremblay C, Routy JP, Grayson T, Sun C, Wang S, Learn GH, Morgan CJ, Schumacher JE, Haynes BF, Keele BF, Hahn BH, Shaw GM. Wide variation in the multiplicity of HIV-1 infection among injection drug users. Journal of Virology. 84: 6241-7. PMID 20375173 DOI: 10.1128/Jvi.00077-10 |
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Yeh WW, Rahman I, Hraber P, Coffey RT, Nevidomskyte D, Giri A, Asmal M, Miljkovic S, Daniels M, Whitney JB, Keele BF, Hahn BH, Korber BT, Shaw GM, Seaman MS, et al. Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys. Journal of Virology. 84: 6018-32. PMID 20357097 DOI: 10.1128/Jvi.02741-09 |
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Kraus MH, Parrish NF, Shaw KS, Decker JM, Keele BF, Salazar-Gonzalez JF, Grayson T, McPherson DT, Ping LH, Anderson JA, Swanstrom R, Williamson C, Shaw GM, Hahn BH. A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays. Virology. 397: 346-57. PMID 20003995 DOI: 10.1016/J.Virol.2009.11.019 |
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Goonetilleke N, Liu M, Ganusov V, Giorgi E, Salazar J, Li H, Kirchner J, Turnbull E, Bourne V, Moore S, Yang H, Keele B, Borrow P, Cohen M, Perelson A, et al. The Role of T Cell Immunity in the Control of HIV Infection International Journal of Infectious Diseases. 14: e19-e20. DOI: 10.1016/J.Ijid.2010.02.1528 |
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Keele BF, Derdeyn CA. Genetic and antigenic features of the transmitted virus. Current Opinion in Hiv and Aids. 4: 352-7. PMID 20048697 DOI: 10.1097/Coh.0B013E32832D9Fef |
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Sauter D, Schindler M, Specht A, Landford WN, Münch J, Kim KA, Votteler J, Schubert U, Bibollet-Ruche F, Keele BF, Takehisa J, Ogando Y, Ochsenbauer C, Kappes JC, Ayouba A, et al. Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. Cell Host & Microbe. 6: 409-21. PMID 19917496 DOI: 10.1016/J.Chom.2009.10.004 |
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Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Modeling sequence evolution in acute HIV-1 infection. Journal of Theoretical Biology. 261: 341-60. PMID 19660475 DOI: 10.1016/J.Jtbi.2009.07.038 |
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Keele BF, Jones JH, Terio KA, Estes JD, Rudicell RS, Wilson ML, Li Y, Learn GH, Beasley TM, Schumacher-Stankey J, Wroblewski E, Mosser A, Raphael J, Kamenya S, Lonsdorf EV, et al. Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz. Nature. 460: 515-9. PMID 19626114 DOI: 10.1038/Nature08200 |
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Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, Li H, Decker JM, Wang S, Baalwa J, Kraus MH, Parrish NF, Shaw KS, Guffey MB, Bar KJ, Davis KL, et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. The Journal of Experimental Medicine. 206: 1273-89. PMID 19487424 DOI: 10.1084/Jem.20090378 |
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Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, Keele BF, Learn GH, Turnbull EL, Salazar MG, Weinhold KJ, Moore S, Letvin N, Haynes BF, et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. The Journal of Experimental Medicine. 206: 1253-72. PMID 19487423 DOI: 10.1084/Jem.20090365 |
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Turnbull EL, Wong M, Wang S, Wei X, Jones NA, Conrod KE, Aldam D, Turner J, Pellegrino P, Keele BF, Williams I, Shaw GM, Borrow P. Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 182: 7131-45. PMID 19454710 DOI: 10.4049/jimmunol.0803658 |
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Wood N, Bhattacharya T, Keele BF, Giorgi E, Liu M, Gaschen B, Daniels M, Ferrari G, Haynes BF, McMichael A, Shaw GM, Hahn BH, Korber B, Seoighe C. HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC. Plos Pathogens. 5: e1000414. PMID 19424423 DOI: 10.1371/Journal.Ppat.1000414 |
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Keele BF, Li H, Learn GH, Hraber P, Giorgi EE, Grayson T, Sun C, Chen Y, Yeh WW, Letvin NL, Mascola JR, Nabel GJ, Haynes BF, Bhattacharya T, Perelson AS, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. The Journal of Experimental Medicine. 206: 1117-34. PMID 19414559 DOI: 10.1084/Jem.20082831 |
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Wilson NA, Keele BF, Reed JS, Piaskowski SM, MacNair CE, Bett AJ, Liang X, Wang F, Thoryk E, Heidecker GJ, Citron MP, Huang L, Lin J, Vitelli S, Ahn CD, et al. Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge. Journal of Virology. 83: 6508-21. PMID 19403685 DOI: 10.1128/Jvi.00272-09 |
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Abrahams MR, Anderson JA, Giorgi EE, Seoighe C, Mlisana K, Ping LH, Athreya GS, Treurnicht FK, Keele BF, Wood N, Salazar-Gonzalez JF, Bhattacharya T, Chu H, Hoffman I, Galvin S, et al. Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. Journal of Virology. 83: 3556-67. PMID 19193811 DOI: 10.1128/Jvi.02132-08 |
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Shen X, Parks RJ, Montefiori DC, Kirchherr JL, Keele BF, Decker JM, Blattner WA, Gao F, Weinhold KJ, Hicks CB, Greenberg ML, Hahn BH, Shaw GM, Haynes BF, Tomaras GD. In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth. Journal of Virology. 83: 3617-25. PMID 19193787 DOI: 10.1128/Jvi.02631-08 |
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Haaland RE, Hawkins PA, Salazar-Gonzalez J, Johnson A, Tichacek A, Karita E, Manigart O, Mulenga J, Keele BF, Shaw GM, Hahn BH, Allen SA, Derdeyn CA, Hunter E. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1. Plos Pathogens. 5: e1000274. PMID 19165325 DOI: 10.1371/Journal.Ppat.1000274 |
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Thacker TC, Zhou X, Estes JD, Jiang Y, Keele BF, Elton TS, Burton GF. Follicular dendritic cells and human immunodeficiency virus type 1 transcription in CD4+ T cells. Journal of Virology. 83: 150-8. PMID 18971284 DOI: 10.1128/Jvi.01652-08 |
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Stone M, Keele BF, Ma Z, Bailes E, Dutra J, Hahn BH, Shaw GM, Miller CJ. P20-13. Identification and characterization of early founder populations in Rhesus macaques vaginally infected with SIVmac251 Retrovirology. 6: P383. DOI: 10.1186/1742-4690-6-S3-P383 |
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Bar KJ, Keele BF, Decker J, McLellan J, Salazar-Gonzales J, Salazar M, Li H, Wang S, Yang Y, Hahn BH, Kwong PD, Shaw GM. P04-43. Neutralizing antibody responses against conformational envelope epitopes in early HIV-1 infection Retrovirology. 6. |
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Yeh WW, Rahman I, Hraber P, Giri A, Nevidomskyte D, Coffey RT, Asmal M, Miljkovic S, Whitney JB, Keele BF, Shaw GM, Korber BT, Seaman MS, Letvin NL. P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys Retrovirology. 6. |
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Tomaras GD, Yates NL, Liu P, Qin L, Fouda GG, Chavez LL, Decamp AC, Parks RJ, Ashley VC, Lucas JT, Cohen M, Eron J, Hicks CB, Liao HX, Self SG, ... ... Keele BF, et al. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. Journal of Virology. 82: 12449-63. PMID 18842730 DOI: 10.1128/Jvi.01708-08 |
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Liu W, Worobey M, Li Y, Keele BF, Bibollet-Ruche F, Guo Y, Goepfert PA, Santiago ML, Ndjango JB, Neel C, Clifford SL, Sanz C, Kamenya S, Wilson ML, Pusey AE, et al. Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees. Plos Pathogens. 4: e1000097. PMID 18604273 DOI: 10.1371/Journal.Ppat.1000097 |
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Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 105: 7552-7. PMID 18490657 DOI: 10.1073/Pnas.0802203105 |
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Keele BF, Tazi L, Gartner S, Liu Y, Burgon TB, Estes JD, Thacker TC, Crandall KA, McArthur JC, Burton GF. Characterization of the follicular dendritic cell reservoir of human immunodeficiency virus type 1. Journal of Virology. 82: 5548-61. PMID 18385252 DOI: 10.1128/Jvi.00124-08 |
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Heuverswyn FV, Li Y, Bailes E, Neel C, Lafay B, Keele BF, Shaw KS, Takehisa J, Kraus MH, Loul S, Butel C, Liegeois F, Yangda B, Sharp PM, Mpoudi-Ngole E, et al. Genetic diversity and phylogeographic clustering of SIVcpzPtt in wild chimpanzees in Cameroon Virology. 368: 155-171. PMID 17651775 DOI: 10.1016/J.Virol.2007.06.018 |
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| 2007 |
Wain LV, Bailes E, Bibollet-Ruche F, Decker JM, Keele BF, Van Heuverswyn F, Li Y, Takehisa J, Ngole EM, Shaw GM, Peeters M, Hahn BH, Sharp PM. Adaptation of HIV-1 to Its Human Host Molecular Biology and Evolution. 24: 1853-1860. PMID 17545188 DOI: 10.1093/Molbev/Msm110 |
0.519 |
|
| 2007 |
Takehisa J, Kraus MH, Decker JM, Li Y, Keele BF, Bibollet-Ruche F, Zammit KP, Weng Z, Santiago ML, Kamenya S, Wilson ML, Pusey AE, Bailes E, Sharp PM, Shaw GM, et al. Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees. Journal of Virology. 81: 7463-75. PMID 17494082 DOI: 10.1128/Jvi.00551-07 |
0.34 |
|
| 2006 |
Van Heuverswyn F, Li Y, Neel C, Bailes E, Keele BF, Liu W, Loul S, Butel C, Liegeois F, Bienvenue Y, Ngolle EM, Sharp PM, Shaw GM, Delaporte E, Hahn BH, et al. Human immunodeficiency viruses: SIV infection in wild gorillas Nature. 444: 164. PMID 17093443 DOI: 10.1038/444164A |
0.494 |
|
| 2006 |
Keele BF, Van Heuverswyn F, Li Y, Bailes E, Takehisa J, Santiago ML, Bibollet-Ruche F, Chen Y, Wain LV, Liegeois F, Loul S, Ngole EM, Bienvenue Y, Delaporte E, Brookfield JF, et al. Chimpanzee reservoirs of pandemic and nonpandemic HIV-1. Science (New York, N.Y.). 313: 523-6. PMID 16728595 DOI: 10.1126/Science.1126531 |
0.502 |
|
| 2005 |
Santiago ML, Range F, Keele BF, Li Y, Bailes E, Bibollet-Ruche F, Fruteau C, Noë R, Peeters M, Brookfield JF, Shaw GM, Sharp PM, Hahn BH. Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2. Journal of Virology. 79: 12515-27. PMID 16160179 DOI: 10.1128/Jvi.79.19.12515-12527.2005 |
0.45 |
|
| 2004 |
Estes JD, Thacker TC, Hampton DL, Kell SA, Keele BF, Palenske EA, Druey KM, Burton GF. Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration. Journal of Immunology (Baltimore, Md. : 1950). 173: 6169-78. PMID 15528354 DOI: 10.4049/Jimmunol.173.10.6169 |
0.752 |
|
| 2004 |
Worobey M, Santiago ML, Keele BF, Ndjango JBN, Joy JB, Labama BL, Dhed'a BD, Rambaut A, Sharp PM, Shaw GM, Hahn BH. Contaminated polio vaccine theory refuted Nature. 428: 820. PMID 15103367 DOI: 10.1038/428820A |
0.392 |
|
| 2002 |
Estes JD, Keele BF, Tenner-Racz K, Racz P, Redd MA, Thacker TC, Jiang Y, Lloyd MJ, Gartner S, Burton GF. Follicular dendritic cell-mediated up-regulation of CXCR4 expression on CD4 T cells and HIV pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 169: 2313-22. PMID 12193696 DOI: 10.4049/Jimmunol.169.5.2313 |
0.808 |
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| 2002 |
Burton GF, Keele BF, Estes JD, Thacker TC, Gartner S. Follicular dendritic cell contributions to HIV pathogenesis. Seminars in Immunology. 14: 275-84. PMID 12163303 DOI: 10.1016/S1044-5323(02)00060-X |
0.831 |
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| 2002 |
Smith-Franklin BA, Keele BF, Tew JG, Gartner S, Szakal AK, Estes JD, Thacker TC, Burton GF. Follicular dendritic cells and the persistence of HIV infectivity: the role of antibodies and Fcgamma receptors. Journal of Immunology (Baltimore, Md. : 1950). 168: 2408-14. PMID 11859132 DOI: 10.4049/Jimmunol.168.5.2408 |
0.827 |
|
| 2001 |
Smith BA, Gartner S, Liu Y, Perelson AS, Stilianakis NI, Keele BF, Kerkering TM, Ferreira-Gonzalez A, Szakal AK, Tew JG, Burton GF. Persistence of infectious HIV on follicular dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 690-6. PMID 11123354 DOI: 10.4049/Jimmunol.166.1.690 |
0.803 |
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