| Year |
Citation |
Score |
| 2024 |
Jang S, Bedwell GJ, Singh SP, Yu HJ, Arnarson B, Singh PK, Radhakrishnan R, Douglas AW, Ingram ZM, Freniere C, Akkermans O, Sarafianos SG, Ambrose Z, Xiong Y, Anekal PV, et al. HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration. Nucleic Acids Research. PMID 39258548 DOI: 10.1093/nar/gkae769 |
0.437 |
|
| 2024 |
Ingram Z, Kline C, Hughson AK, Singh PK, Fischer HL, Sowd GA, Watkins SC, Kane M, Engelman AN, Ambrose Z. Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration. Biorxiv : the Preprint Server For Biology. PMID 38645162 DOI: 10.1101/2024.04.08.588584 |
0.437 |
|
| 2023 |
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Hawes CE, Lakshmanappa YS, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. Deep analysis of CD4 T cells in the rhesus CNS during SIV infection. Plos Pathogens. 19: e1011844. PMID 38060615 DOI: 10.1371/journal.ppat.1011844 |
0.414 |
|
| 2023 |
Roy CN, Shu ST, Kline C, Rigatti L, Smithgall TE, Ambrose Z. Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission. Scientific Reports. 13: 17067. PMID 37816950 DOI: 10.1038/s41598-023-44366-2 |
0.348 |
|
| 2023 |
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. CD4 T cell Responses in the CNS during SIV infection. Biorxiv : the Preprint Server For Biology. PMID 37662237 DOI: 10.1101/2023.08.24.554055 |
0.425 |
|
| 2022 |
Dwivedi R, Wang Y, Kline C, Fischer DK, Ambrose Z. APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants. Frontiers in Virology. 2. PMID 35957953 DOI: 10.3389/fviro.2022.919825 |
0.494 |
|
| 2021 |
Tisthammer KH, Kline C, Rutledge T, Diedrich CR, Ita S, Lin PL, Ambrose Z, Pennings PS. SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV- Co-Infection. Viruses. 14. PMID 35062252 DOI: 10.3390/v14010048 |
0.422 |
|
| 2021 |
Ingram Z, Fischer DK, Ambrose Z. Disassembling the Nature of Capsid: Biochemical, Genetic, and Imaging Approaches to Assess HIV-1 Capsid Functions. Viruses. 13. PMID 34835043 DOI: 10.3390/v13112237 |
0.5 |
|
| 2021 |
Roy CN, Benitez Moreno MA, Kline C, Ambrose Z. CG dinucleotide removal in bioluminescent and fluorescent reporters improves HIV-1 replication and reporter gene expression for dual imaging in humanized mice. Journal of Virology. JVI0044921. PMID 34232063 DOI: 10.1128/JVI.00449-21 |
0.513 |
|
| 2021 |
Zhong Z, Ning J, Boggs EA, Jang S, Wallace C, Telmer C, Bruchez MP, Ahn J, Engelman AN, Zhang P, Watkins SC, Ambrose Z. Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner. Mbio. 12. PMID 33758083 DOI: 10.1128/mBio.03142-20 |
0.554 |
|
| 2020 |
Xu C, Fischer DK, Rankovic S, Li W, Dick RA, Runge B, Zadorozhnyi R, Ahn J, Aiken C, Polenova T, Engelman AN, Ambrose Z, Rousso I, Perilla JR. Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis. Plos Biology. 18: e3001015. PMID 33332391 DOI: 10.1371/journal.pbio.3001015 |
0.42 |
|
| 2020 |
Diedrich CR, Rutledge T, Maiello P, Baranowski TM, White AG, Borish HJ, Karell P, Hopkins F, Brown J, Fortune SM, Flynn JL, Ambrose Z, Lin PL. SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis. Plos Pathogens. 16: e1008413. PMID 32730321 DOI: 10.1371/Journal.Ppat.1008413 |
0.41 |
|
| 2020 |
Melody K, Roy CN, Kline C, Cottrell ML, Evans D, Shutt K, Pennings PS, Keele BF, Bility M, Kashuba ADM, Ambrose Z. Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice. Journal of Virology. PMID 31969438 DOI: 10.1128/Jvi.01912-19 |
0.565 |
|
| 2019 |
Fu X, Ning J, Zhong Z, Ambrose Z, Charles Watkins S, Zhang P. AutoCLEM: An Automated Workflow for Correlative Live-Cell Fluorescence Microscopy and Cryo-Electron Tomography. Scientific Reports. 9: 19207. PMID 31844138 DOI: 10.1038/S41598-019-55766-8 |
0.312 |
|
| 2019 |
Siddiqui MA, Saito A, Halambage UD, Ferhadian D, Fischer DK, Francis AC, Melikyan GB, Ambrose Z, Aiken C, Yamashita M. A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing. Journal of Virology. PMID 31167922 DOI: 10.1128/Jvi.00706-19 |
0.454 |
|
| 2019 |
Boyer PL, Melody K, Smith SJ, Dunn LL, Kline C, Fischer DK, Dwivedi R, Clark P, Hughes SH, Ambrose Z. Two Co-Selected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Non-nucleoside RT Inhibitors and Nucleoside Analogs. Journal of Virology. PMID 30894467 DOI: 10.1128/Jvi.00224-19 |
0.423 |
|
| 2019 |
Fischer DK, Saito A, Kline C, Cohen R, Watkins SC, Yamashita M, Ambrose Z. CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes. Journal of Virology. PMID 30814280 DOI: 10.1128/Jvi.00214-19 |
0.594 |
|
| 2018 |
Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P. Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid. Journal of Virology. PMID 29643241 DOI: 10.1128/Jvi.00368-18 |
0.574 |
|
| 2017 |
Akiyama H, Ramirez NP, Gibson G, Kline C, Watkins S, Ambrose Z, Gummuluru S. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of IFN-α. Journal of Virology. PMID 28794041 DOI: 10.1128/Jvi.00972-17 |
0.52 |
|
| 2017 |
Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z. A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host. Plos Pathogens. 13: e1006358. PMID 28542550 DOI: 10.1371/Journal.Ppat.1006358 |
0.543 |
|
| 2016 |
Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N. Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro. Journal of Virology. 90: 8059-73. PMID 27356901 DOI: 10.1128/Jvi.00553-16 |
0.548 |
|
| 2016 |
Smith SJ, Pauly GT, Akram A, Melody K, Ambrose Z, Schneider JP, Hughes SH. Rilpivirine and Doravirine have complementary efficacies against NNRTI-Resistant HIV-1 mutants. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27124362 DOI: 10.1097/Qai.0000000000001031 |
0.516 |
|
| 2016 |
Smith SJ, Pauly GT, Akram A, Melody K, Rai G, Maloney DJ, Ambrose Z, Thomas CJ, Schneider JT, Hughes SH. Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants. Retrovirology. 13: 11. PMID 26880034 DOI: 10.1186/S12977-016-0244-2 |
0.512 |
|
| 2015 |
Kearney MF, Anderson EM, Coomer C, Smith L, Shao W, Johnson N, Kline C, Spindler J, Mellors JW, Coffin JM, Ambrose Z. Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy. Retrovirology. 12: 93. PMID 26559632 DOI: 10.1186/S12977-015-0212-2 |
0.434 |
|
| 2015 |
Melody K, McBeth S, Kline C, Kashuba AD, Mellors JW, Ambrose Z. Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase. Antimicrobial Agents and Chemotherapy. 59: 7762-70. PMID 26438501 DOI: 10.1128/Aac.01937-15 |
0.546 |
|
| 2015 |
Song J, Cai Z, White AG, Jin T, Wang X, Kadayakkara D, Anderson CJ, Ambrose Z, Young WB. Visualization and quantification of simian immunodeficiency virus (SIV)-infected cells using non-invasive molecular imaging. The Journal of General Virology. PMID 26297664 DOI: 10.1099/Jgv.0.000245 |
0.414 |
|
| 2014 |
Ambrose Z, Kline C, Polacino P, Hu SL. Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy. Journal of Medical Primatology. 43: 298-309. PMID 24784552 DOI: 10.1111/Jmp.12126 |
0.557 |
|
| 2014 |
Ambrose Z, Aiken C. HIV-1 uncoating: connection to nuclear entry and regulation by host proteins. Virology. 454: 371-9. PMID 24559861 DOI: 10.1016/J.Virol.2014.02.004 |
0.533 |
|
| 2014 |
Song J, Young W, Cai Z, Jin T, Wang X, Kadayakkara D, Anderson C, Ambrose Z. P-B3 Visualize and quantify simian immunodeficiency virus-infected cells in vivo Jaids Journal of Acquired Immune Deficiency Syndromes. 67: 83. DOI: 10.1097/01.Qai.0000456183.19724.3F |
0.407 |
|
| 2014 |
Zhang P, Jun S, Zhao G, Ambrose Z, Watkins SC. Correlative imaging and cryo-FIB processing for direct visualization of HIV-1 infection Microscopy and Microanalysis. 20: 974-975. DOI: 10.1017/S143192761400659X |
0.398 |
|
| 2013 |
Kline C, Ndjomou J, Franks T, Kiser R, Coalter V, Smedley J, Piatak M, Mellors JW, Lifson JD, Ambrose Z. Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model. Plos One. 8: e84275. PMID 24367650 DOI: 10.1371/Journal.Pone.0084275 |
0.575 |
|
| 2013 |
Xu H, Franks T, Gibson G, Huber K, Rahm N, De Castillia CS, Luban J, Aiken C, Watkins S, Sluis-Cremer N, Ambrose Z. Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology. 10: 70. PMID 23835323 DOI: 10.1186/1742-4690-10-70 |
0.564 |
|
| 2012 |
Boltz VF, Ambrose Z, Kearney MF, Shao W, Kewalramani VN, Maldarelli F, Mellors JW, Coffin JM. Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase. Journal of Virology. 86: 12525-30. PMID 22933296 DOI: 10.1128/Jvi.01963-12 |
0.534 |
|
| 2012 |
Acevedo O, Ambrose Z, Flaherty PT, Aamer H, Jain P, Sambasivarao SV. Identification of HIV inhibitors guided by free energy perturbation calculations. Current Pharmaceutical Design. 18: 1199-216. PMID 22316150 DOI: 10.2174/138920012799362828 |
0.545 |
|
| 2012 |
Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN. Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. Journal of Virology. 86: 4708-14. PMID 22301145 DOI: 10.1128/Jvi.05887-11 |
0.608 |
|
| 2011 |
Jun S, Ke D, Debiec K, Zhao G, Meng X, Ambrose Z, Gibson GA, Watkins SC, Zhang P. Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography. Structure (London, England : 1993). 19: 1573-81. PMID 22078557 DOI: 10.1016/J.Str.2011.09.006 |
0.557 |
|
| 2011 |
Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, KewalRamani VN, Mellors JW, Coffin JM, Ambrose Z. Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy. Journal of Virology. 85: 1067-76. PMID 21084490 DOI: 10.1128/Jvi.01701-10 |
0.574 |
|
| 2010 |
Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, et al. Flexible use of nuclear import pathways by HIV-1. Cell Host & Microbe. 7: 221-33. PMID 20227665 DOI: 10.1016/J.Chom.2010.02.007 |
0.556 |
|
| 2009 |
Shao W, Kearney M, Maldarelli F, Mellors JW, Stephens RM, Lifson JD, KewalRamani VN, Ambrose Z, Coffin JM, Palmer SE. RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy. Retrovirology. 6: 101. PMID 19889213 DOI: 10.1186/1742-4690-6-101 |
0.562 |
|
| 2009 |
Boyer PL, Vu BC, Ambrose Z, Julias JG, Warnecke S, Liao C, Meier C, Marquez VE, Hughes SH. The nucleoside analogue D-carba T blocks HIV-1 reverse transcription. Journal of Medicinal Chemistry. 52: 5356-64. PMID 19678643 DOI: 10.1021/Jm801176E |
0.526 |
|
| 2009 |
Hatziioannou T, Ambrose Z, Chung NP, Piatak M, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, et al. A macaque model of HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 106: 4425-9. PMID 19255423 DOI: 10.1073/Pnas.0812587106 |
0.613 |
|
| 2009 |
Ambrose Z, Herman BD, Sheen CW, Zelina S, Moore KL, Tachedjian G, Nissley DV, Sluis-Cremer N. The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs. Journal of Virology. 83: 3826-33. PMID 19193782 DOI: 10.1128/Jvi.01968-08 |
0.48 |
|
| 2009 |
Lee K, Martin TD, Ambrose Z, Mulky A, KewalRamani VN. 117 CA-Dependent HIV-1 Nuclear Import Relies on Transportin-SR2 Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351074.66837.E3 |
0.442 |
|
| 2008 |
Ambrose Z, Compton L, Piatak M, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN. Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges. Journal of Virology. 82: 6591-9. PMID 18434406 DOI: 10.1128/Jvi.02730-07 |
0.582 |
|
| 2008 |
Ambrose Z, KewalRamani VN. Of mice and monkeys: New advances in animal models to study HIV-1 therapy and prophylaxis Future Hiv Therapy. 2: 363-373. DOI: 10.2217/17469600.2.4.363 |
0.618 |
|
| 2007 |
Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, et al. Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy. Journal of Virology. 81: 12145-55. PMID 17855539 DOI: 10.1128/Jvi.01301-07 |
0.589 |
|
| 2007 |
Boyer PL, Julias JG, Ambrose Z, Siddiqui MA, Marquez VE, Hughes SH. The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants. Journal of Molecular Biology. 371: 873-82. PMID 17597154 DOI: 10.1016/J.Jmb.2007.05.043 |
0.461 |
|
| 2007 |
Ambrose Z, KewalRamani VN, Bieniasz PD, Hatziioannou T. HIV/AIDS: in search of an animal model. Trends in Biotechnology. 25: 333-7. PMID 17574286 DOI: 10.1016/J.Tibtech.2007.05.004 |
0.601 |
|
| 2007 |
Nissley DV, Radzio J, Ambrose Z, Sheen CW, Hamamouch N, Moore KL, Tachedjian G, Sluis-Cremer N. Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT. The Biochemical Journal. 404: 151-7. PMID 17286555 DOI: 10.1042/Bj20061814 |
0.464 |
|
| 2006 |
Ambrose Z, Julias JG, Boyer PL, Kewalramani VN, Hughes SH. The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine. Journal of Virology. 80: 2578-81. PMID 16474164 DOI: 10.1128/Jvi.80.5.2578-2581.2006 |
0.535 |
|
| 2004 |
Ambrose Z, Boltz V, Palmer S, Coffin JM, Hughes SH, Kewalramani VN. In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques. Journal of Virology. 78: 13553-61. PMID 15564466 DOI: 10.1128/Jvi.78.24.13553-13561.2004 |
0.608 |
|
| 2003 |
Ambrose Z, Thompson J, Larsen K, Kuller L, Panicali DL, Clements JD, Agy M, Montefiori DC, Hu SL, Bosch ML. Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6). Virology. 308: 178-90. PMID 12706101 DOI: 10.1016/S0042-6822(03)00027-8 |
0.629 |
|
| 2001 |
Ambrose Z, Larsen K, Thompson J, Stevens Y, Finn E, Hu SL, Bosch ML. Evidence for early local viral replication and local production of antiviral immunity upon mucosal simian-human immunodeficiency virus SHIV(89.6) infection in Macaca nemestrina. Journal of Virology. 75: 8589-96. PMID 11507204 DOI: 10.1128/Jvi.75.18.8589-8596.2001 |
0.686 |
|
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