| Year |
Citation |
Score |
| 2021 |
Chatterjee Bhowmick D, Ahn M, Oh E, Veluthakal R, Thurmond DC. Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection. International Journal of Molecular Sciences. 22. PMID 33673206 DOI: 10.3390/ijms22041833 |
0.466 |
|
| 2020 |
Merz KE, Thurmond DC. Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake. Comprehensive Physiology. 10: 785-809. PMID 32940941 DOI: 10.1002/cphy.c190029 |
0.556 |
|
| 2019 |
Zhang J, Oh E, Merz KE, Aslamy A, Veluthakal R, Salunkhe VA, Ahn M, Tunduguru R, Thurmond DC. DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle. Diabetologia. PMID 30707251 DOI: 10.1007/S00125-019-4824-2 |
0.713 |
|
| 2018 |
Oh E, Ahn M, Afelik S, Becker TC, Roep BO, Thurmond DC. Syntaxin 4 Expression in Pancreatic β-Cells Promotes and Protects Functional β-Cell Mass. Diabetes. PMID 30305365 DOI: 10.2337/db18-0259 |
0.441 |
|
| 2018 |
Veluthakal R, Chepurny OG, Leech CA, Schwede F, Holz GG, Thurmond DC. Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets. Diabetes. PMID 29986926 DOI: 10.2337/Db17-1174 |
0.566 |
|
| 2018 |
Salunkhe VA, Veluthakal R, Kahn SE, Thurmond DC. Novel approaches to restore beta cell function in prediabetes and type 2 diabetes. Diabetologia. PMID 29947922 DOI: 10.1007/S00125-018-4658-3 |
0.414 |
|
| 2018 |
Aslamy A, Oh E, Olson EM, Zhang J, Ahn M, Md Moin AS, Tunduguru R, Salunkhe VA, Veluthakal R, Thurmond DC. Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function. Diabetes. PMID 29661782 DOI: 10.2337/db17-1352 |
0.328 |
|
| 2017 |
Tunduguru R, Thurmond DC. Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out. Frontiers in Endocrinology. 8: 329. PMID 29209279 DOI: 10.3389/fendo.2017.00329 |
0.6 |
|
| 2017 |
Tunduguru R, Zhang J, Aslamy A, Salunkhe VA, Brozinick JT, Elmendorf JS, Thurmond DC. The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells. The Journal of Biological Chemistry. PMID 28972183 DOI: 10.1074/Jbc.M117.801340 |
0.558 |
|
| 2017 |
Aslamy A, Thurmond DC. Exocytosis Proteins as Novel Targets for Diabetes Prevention and/or Remediation? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00002.2017. PMID 28356294 DOI: 10.1152/ajpregu.00002.2017 |
0.463 |
|
| 2015 |
Oh E, Miller RA, Thurmond DC. Syntaxin 4 Overexpression Ameliorates Effects of Aging and High-Fat Diet on Glucose Control and Extends Lifespan. Cell Metabolism. 22: 499-507. PMID 26331606 DOI: 10.1016/j.cmet.2015.07.023 |
0.611 |
|
| 2015 |
Veluthakal R, Tunduguru R, Arora DK, Sidarala V, Syeda K, Vlaar CP, Thurmond DC, Kowluru A. VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells. Diabetologia. 58: 2573-81. PMID 26224100 DOI: 10.1007/S00125-015-3707-4 |
0.493 |
|
| 2015 |
Blue EK, Ballman K, Boyle F, Oh E, Kono T, Quinney SK, Thurmond DC, Evans-Molina C, Haneline LS. Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats. Pediatric Research. 77: 316-25. PMID 25412163 DOI: 10.1038/Pr.2014.185 |
0.362 |
|
| 2014 |
Tunduguru R, Chiu TT, Ramalingam L, Elmendorf JS, Klip A, Thurmond DC. Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells. Biochemical Pharmacology. 92: 380-8. PMID 25199455 DOI: 10.1016/J.Bcp.2014.08.033 |
0.696 |
|
| 2014 |
Ramalingam L, Lu J, Hudmon A, Thurmond DC. Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells. The Biochemical Journal. 464: 251-8. PMID 25190515 DOI: 10.1042/Bj20140845 |
0.365 |
|
| 2014 |
Ramalingam L, Yoder SM, Oh E, Thurmond DC. Munc18c: a controversial regulator of peripheral insulin action. Trends in Endocrinology and Metabolism: Tem. 25: 601-8. PMID 25028245 DOI: 10.1016/j.tem.2014.06.010 |
0.685 |
|
| 2014 |
Ramalingam L, Oh E, Thurmond DC. Doc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivity. Diabetologia. 57: 1476-84. PMID 24705606 DOI: 10.1007/s00125-014-3227-7 |
0.693 |
|
| 2014 |
Yoder SM, Dineen SL, Wang Z, Thurmond DC. YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cells. The Journal of Biological Chemistry. 289: 11476-87. PMID 24610809 DOI: 10.1074/jbc.M114.559328 |
0.567 |
|
| 2014 |
Oh E, Stull ND, Mirmira RG, Thurmond DC. Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 99: E866-70. PMID 24552216 DOI: 10.1210/jc.2013-2221 |
0.433 |
|
| 2013 |
Kalwat MA, Thurmond DC. Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells. Experimental & Molecular Medicine. 45: e37. PMID 23969997 DOI: 10.1038/emm.2013.73 |
0.589 |
|
| 2013 |
Kalwat MA, Yoder SM, Wang Z, Thurmond DC. A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells. Biochemical Pharmacology. 85: 808-16. PMID 23246867 DOI: 10.1016/J.Bcp.2012.12.003 |
0.544 |
|
| 2013 |
Ramalingam L, Oh E, Thurmond DC. Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates. Cellular and Molecular Life Sciences : Cmls. 70: 2815-34. PMID 23052216 DOI: 10.1007/s00018-012-1176-1 |
0.596 |
|
| 2012 |
Ramalingam L, Oh E, Yoder SM, Brozinick JT, Kalwat MA, Groffen AJ, Verhage M, Thurmond DC. Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity. Diabetes. 61: 2424-32. PMID 22698913 DOI: 10.2337/Db11-1525 |
0.755 |
|
| 2012 |
Jain SS, Snook LA, Glatz JF, Luiken JJ, Holloway GP, Thurmond DC, Bonen A. Munc18c provides stimulus-selective regulation of GLUT4 but not fatty acid transporter trafficking in skeletal muscle. Febs Letters. 586: 2428-35. PMID 22687245 DOI: 10.1016/J.Febslet.2012.05.061 |
0.522 |
|
| 2012 |
Oh E, Kalwat MA, Kim MJ, Verhage M, Thurmond DC. Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms. The Journal of Biological Chemistry. 287: 25821-33. PMID 22685295 DOI: 10.1074/Jbc.M112.361501 |
0.579 |
|
| 2012 |
Wiseman DA, Thurmond DC. The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act. Current Diabetes Reviews. 8: 303-15. PMID 22587517 DOI: 10.2174/157339912800840514 |
0.371 |
|
| 2012 |
Kalwat MA, Wiseman DA, Luo W, Wang Z, Thurmond DC. Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis. Molecular Endocrinology (Baltimore, Md.). 26: 128-41. PMID 22108804 DOI: 10.1210/Me.2011-1112 |
0.545 |
|
| 2011 |
Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD. Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. Plos Genetics. 7: e1002323. PMID 21998599 DOI: 10.1371/Journal.Pgen.1002323 |
0.57 |
|
| 2011 |
Wang Z, Oh E, Clapp DW, Chernoff J, Thurmond DC. Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo. The Journal of Biological Chemistry. 286: 41359-67. PMID 21969371 DOI: 10.1074/Jbc.M111.291500 |
0.614 |
|
| 2011 |
Kepner EM, Yoder SM, Oh E, Kalwat MA, Wang Z, Quilliam LA, Thurmond DC. Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 301: E1072-80. PMID 21828338 DOI: 10.1152/Ajpendo.00312.2011 |
0.563 |
|
| 2011 |
Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC. Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. The Journal of Cell Biology. 193: 185-99. PMID 21444687 DOI: 10.1083/Jcb.201007176 |
0.47 |
|
| 2011 |
Wiseman DA, Kalwat MA, Thurmond DC. Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosis. The Journal of Biological Chemistry. 286: 16344-54. PMID 21393240 DOI: 10.1074/Jbc.M110.214031 |
0.568 |
|
| 2010 |
Jewell JL, Oh E, Thurmond DC. Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R517-31. PMID 20053958 DOI: 10.1152/Ajpregu.00597.2009 |
0.592 |
|
| 2010 |
Wang Z, Thurmond DC. Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion. The Journal of Biological Chemistry. 285: 6186-97. PMID 20028975 DOI: 10.1074/Jbc.M109.072421 |
0.47 |
|
| 2009 |
Thurmond DC. Insulin-regulated glucagon-like peptide-1 release from L cells: actin' out. Endocrinology. 150: 5202-4. PMID 19933397 DOI: 10.1210/en.2009-1178 |
0.365 |
|
| 2009 |
Wang Z, Thurmond DC. Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins. Journal of Cell Science. 122: 893-903. PMID 19295123 DOI: 10.1242/jcs.034355 |
0.513 |
|
| 2009 |
Oh E, Thurmond DC. Munc18c depletion selectively impairs the sustained phase of insulin release. Diabetes. 58: 1165-74. PMID 19188424 DOI: 10.2337/Db08-1059 |
0.565 |
|
| 2009 |
Habets DD, Thurmond DC, Coumans WA, Bonen A, Glatz JF, Luiken JJ. Munc18c is not rate-limiting for glucose and long-chain fatty acid uptake in the heart. Molecular and Cellular Biochemistry. 322: 81-6. PMID 19009238 DOI: 10.1007/s11010-008-9942-y |
0.525 |
|
| 2008 |
Jewell JL, Oh E, Bennett SM, Meroueh SO, Thurmond DC. The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta. The Journal of Biological Chemistry. 283: 21734-46. PMID 18541526 DOI: 10.1074/Jbc.M710445200 |
0.349 |
|
| 2008 |
Jewell JL, Luo W, Oh E, Wang Z, Thurmond DC. Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4. The Journal of Biological Chemistry. 283: 10716-26. PMID 18285343 DOI: 10.1074/Jbc.M709876200 |
0.417 |
|
| 2007 |
Oh E, Heise CJ, English JM, Cobb MH, Thurmond DC. WNK1 is a novel regulator of Munc18c-syntaxin 4 complex formation in soluble NSF attachment protein receptor (SNARE)-mediated vesicle exocytosis. The Journal of Biological Chemistry. 282: 32613-22. PMID 17848561 DOI: 10.1074/jbc.M706591200 |
0.368 |
|
| 2007 |
Ke B, Oh E, Thurmond DC. Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis. The Journal of Biological Chemistry. 282: 21786-97. PMID 17548353 DOI: 10.1074/Jbc.M701661200 |
0.499 |
|
| 2007 |
Wang Z, Oh E, Thurmond DC. Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion. The Journal of Biological Chemistry. 282: 9536-46. PMID 17289663 DOI: 10.1074/Jbc.M610553200 |
0.567 |
|
| 2007 |
Thurmond DC. Regulation of insulin action and insulin secretion by SNARE-mediated vesicle exocytosis Mechanisms of Insulin Action: Medical Intelligence Unit. 52-70. DOI: 10.1007/978-0-387-72204-7_3 |
0.673 |
|
| 2006 |
Nevins AK, Thurmond DC. Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells. The Journal of Biological Chemistry. 281: 18961-72. PMID 16714282 DOI: 10.1074/Jbc.M603604200 |
0.376 |
|
| 2006 |
Oh E, Thurmond DC. The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis. The Journal of Biological Chemistry. 281: 17624-34. PMID 16638745 DOI: 10.1074/Jbc.M601581200 |
0.399 |
|
| 2006 |
Spurlin BA, Thurmond DC. Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells. Molecular Endocrinology (Baltimore, Md.). 20: 183-93. PMID 16099818 DOI: 10.1210/Me.2005-0157 |
0.67 |
|
| 2005 |
Oh E, Spurlin BA, Pessin JE, Thurmond DC. Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance. Diabetes. 54: 638-47. PMID 15734838 DOI: 10.2337/Diabetes.54.3.638 |
0.715 |
|
| 2005 |
Nevins AK, Thurmond DC. A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis. The Journal of Biological Chemistry. 280: 1944-52. PMID 15537656 DOI: 10.1074/Jbc.M409528200 |
0.537 |
|
| 2004 |
Spurlin BA, Park SY, Nevins AK, Kim JK, Thurmond DC. Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle. Diabetes. 53: 2223-31. PMID 15331531 DOI: 10.2337/Diabetes.53.9.2223 |
0.645 |
|
| 2003 |
Spurlin BA, Thomas RM, Nevins AK, Kim HJ, Kim YJ, Noh HL, Shulman GI, Kim JK, Thurmond DC. Insulin resistance in tetracycline-repressible Munc18c transgenic mice. Diabetes. 52: 1910-7. PMID 12882905 DOI: 10.2337/Diabetes.52.8.1910 |
0.636 |
|
| 2003 |
Nevins AK, Thurmond DC. Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion. American Journal of Physiology. Cell Physiology. 285: C698-710. PMID 12760905 DOI: 10.1152/Ajpcell.00093.2003 |
0.591 |
|
| 2003 |
Thurmond DC, Gonelle-Gispert C, Furukawa M, Halban PA, Pessin JE. Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex. Molecular Endocrinology (Baltimore, Md.). 17: 732-42. PMID 12554769 DOI: 10.1210/Me.2002-0333 |
0.572 |
|
| 2003 |
Chen G, Liu P, Thurmond DC, Elmendorf JS. Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c. Febs Letters. 534: 54-60. PMID 12527361 DOI: 10.1016/S0014-5793(02)03774-2 |
0.47 |
|
| 2001 |
Thurmond DC, Pessin JE. Molecular machinery involved in the insulin-regulated fusion of GLUT4-containing vesicles with the plasma membrane Molecular Membrane Biology. 18: 237-245. PMID 11780752 DOI: 10.1080/09687680110082400 |
0.529 |
|
| 2001 |
Yang C, Coker KJ, Kim JK, Mora S, Thurmond DC, Davis AC, Yang B, Williamson RA, Shulman GI, Pessin JE. Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance. The Journal of Clinical Investigation. 107: 1311-8. PMID 11375421 DOI: 10.1172/Jci12274 |
0.636 |
|
| 2001 |
Chiang SH, Baumann CA, Kanzaki M, Thurmond DC, Watson RT, Neudauer CL, Macara IG, Pessin JE, Saltiel AR. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature. 410: 944-8. PMID 11309621 DOI: 10.1038/35073608 |
0.638 |
|
| 2001 |
Khan AH, Thurmond DC, Yang C, Ceresa BP, Sigmund CD, Pessin JE. Munc18c Regulates Insulin-stimulated GLUT4 Translocation to the Transverse Tubules in Skeletal Muscle Journal of Biological Chemistry. 276: 4063-4069. PMID 11054418 DOI: 10.1074/Jbc.M007419200 |
0.594 |
|
| 2001 |
Thurmond DC, Pessin JE. Molecular basis for insulin-stimulated GLUT4 translocation Current Opinion in Endocrinology and Diabetes. 8: 67-73. DOI: 10.1097/00060793-200104000-00003 |
0.562 |
|
| 2000 |
Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 407: 202-7. PMID 11001060 DOI: 10.1038/35025089 |
0.615 |
|
| 2000 |
Thurmond DC, Pessin JE. Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant Embo Journal. 19: 3565-3575. PMID 10899111 DOI: 10.1093/Emboj/19.14.3565 |
0.373 |
|
| 2000 |
Thurmond DC, Kanzaki M, Khan AH, Pessin JE. Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles Molecular and Cellular Biology. 20: 379-388. PMID 10594040 DOI: 10.1128/Mcb.20.1.379-388.2000 |
0.46 |
|
| 1999 |
Pessin JE, Thurmond DC, Elmendorf JS, Coker KJ, Okada S. Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location! Journal of Biological Chemistry. 274: 2593-2596. PMID 9915783 DOI: 10.1074/Jbc.274.5.2593 |
0.513 |
|
| 1998 |
Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE. Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes Journal of Biological Chemistry. 273: 33876-33883. PMID 9837979 DOI: 10.1074/Jbc.273.50.33876 |
0.527 |
|
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