David A. Knecht - Publications

Affiliations: 
Molecular and Cell Biology University of Connecticut, Storrs, CT, United States 
Area:
cell motility
Website:
http://web.uconn.edu/mcbstaff/knecht/Knecht_Lab/Knecht_Lab.html

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Paschke P, Knecht DA, Williams TD, Thomason PA, Insall RH, Chubb JR, Kay RR, Veltman DM. Genetic Engineering of Dictyostelium discoideum Cells Based on Selection and Growth on Bacteria. Journal of Visualized Experiments : Jove. PMID 30735174 DOI: 10.3791/58981  0.349
2018 Paschke P, Knecht DA, Silale A, Traynor D, Williams TD, Thomason PA, Insall RH, Chubb JR, Kay RR, Veltman DM. Rapid and efficient genetic engineering of both wild type and axenic strains of Dictyostelium discoideum. Plos One. 13: e0196809. PMID 29847546 DOI: 10.1371/Journal.Pone.0196809  0.331
2017 Joshi GN, Gilberti RM, Knecht DA. Single Cell Analysis of Phagocytosis, Phagosome Maturation, Phagolysosomal Leakage, and Cell Death Following Exposure of Macrophages to Silica Particles. Methods in Molecular Biology (Clifton, N.J.). 1519: 55-77. PMID 27815873 DOI: 10.1007/978-1-4939-6581-6_5  0.78
2016 Tweedy L, Knecht DA, Mackay GM, Insall RH. Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis. Plos Biology. 14: e1002404. PMID 26981861 DOI: 10.1371/Journal.Pbio.1002404  0.328
2015 Joshi GN, Goetjen AM, Knecht DA. Silica particles cause NADPH oxidase-independent ROS generation and transient phagolysosomal leakage. Molecular Biology of the Cell. 26: 3150-64. PMID 26202463 DOI: 10.1091/Mbc.E15-03-0126  0.758
2015 Gilberti RM, Knecht DA. Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway. Molecular Biology of the Cell. 26: 518-29. PMID 25428990 DOI: 10.1091/Mbc.E14-08-1301  0.781
2014 Muinonen-Martin AJ, Susanto O, Zhang Q, Smethurst E, Faller WJ, Veltman DM, Kalna G, Lindsay C, Bennett DC, Sansom OJ, Herd R, Jones R, Machesky LM, Wakelam MJ, Knecht DA, et al. Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. Plos Biology. 12: e1001966. PMID 25313567 DOI: 10.1371/Journal.Pbio.1001966  0.363
2014 Veltman DM, Lemieux MG, Knecht DA, Insall RH. PIP₃-dependent macropinocytosis is incompatible with chemotaxis. The Journal of Cell Biology. 204: 497-505. PMID 24535823 DOI: 10.1083/Jcb.201309081  0.384
2014 Lemieux MG, Janzen D, Hwang R, Roldan J, Jarchum I, Knecht DA. Visualization of the actin cytoskeleton: different F-actin-binding probes tell different stories. Cytoskeleton (Hoboken, N.J.). 71: 157-69. PMID 24347465 DOI: 10.1002/Cm.21160  0.348
2014 Joshi GN, Knecht DA. Multi-parametric analysis of intrinsic cell death using live cell microscopy Microscopy and Microanalysis. 20: 1422-1423. DOI: 10.1017/S1431927614008848  0.649
2013 Joshi GN, Knecht DA. Multi-parametric analysis of cell death pathways using live-cell microscopy. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 58: Unit 4.40.. PMID 24510543 DOI: 10.1002/0471140856.Tx0440S58  0.652
2013 Pietrosimone KM, Bhandari S, Lemieux MG, Knecht DA, Lynes MA. In vitro assays of chemotaxis as a window into mechanisms of toxicant-induced immunomodulation. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 58: Unit 18.17.. PMID 24510542 DOI: 10.1002/0471140856.Tx1817S58  0.308
2013 Muinonen-Martin AJ, Knecht DA, Veltman DM, Thomason PA, Kalna G, Insall RH. Measuring chemotaxis using direct visualization microscope chambers. Methods in Molecular Biology (Clifton, N.J.). 1046: 307-21. PMID 23868596 DOI: 10.1007/978-1-62703-538-5_18  0.311
2013 Joshi GN, Knecht DA. Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages. Apoptosis : An International Journal On Programmed Cell Death. 18: 271-85. PMID 23329178 DOI: 10.1007/S10495-012-0798-Y  0.688
2013 Joshi GN, Cheng C, Knecht Da. Investigation of the Role of ROS in Silica Induced Phago-Lysosomal Leakage and Cell Death in Alveolar Macrophages Free Radical Biology and Medicine. 65: S143-S144. DOI: 10.1016/J.Freeradbiomed.2013.10.757  0.649
2012 Pietrosimone KM, Yin X, Knecht DA, Lynes MA. Measurement of cellular chemotaxis with ECIS/Taxis. Journal of Visualized Experiments : Jove. PMID 22491349 DOI: 10.3791/3840  0.339
2011 Costantini LM, Gilberti RM, Knecht DA. The phagocytosis and toxicity of amorphous silica. Plos One. 6: e14647. PMID 21311600 DOI: 10.1371/Journal.Pone.0014647  0.789
2010 Knecht DA, LaFleur RA, Kahsai AW, Argueta CE, Beshir AB, Fenteany G. Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics. Plos One. 5: e14039. PMID 21124831 DOI: 10.1371/Journal.Pone.0014039  0.313
2008 Tang L, Franca-Koh J, Xiong Y, Chen MY, Long Y, Bickford RM, Knecht DA, Iglesias PA, Devreotes PN. tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis. Genes & Development. 22: 2278-90. PMID 18708585 DOI: 10.1101/Gad.1694508  0.316
2008 Gilberti RM, Joshi GN, Knecht DA. The phagocytosis of crystalline silica particles by macrophages. American Journal of Respiratory Cell and Molecular Biology. 39: 619-27. PMID 18556590 DOI: 10.1165/Rcmb.2008-0046Oc  0.773
2008 Luo B, Norris C, Bolstad ES, Knecht DA, Grant DF. Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase. Journal of Molecular Biology. 380: 31-41. PMID 18513744 DOI: 10.1016/J.Jmb.2008.04.064  0.34
2008 Lombardi ML, Knecht DA, Lee J. Mechano-chemical signaling maintains the rapid movement of Dictyostelium cells. Experimental Cell Research. 314: 1850-9. PMID 18359017 DOI: 10.1016/J.Yexcr.2008.02.001  0.331
2008 Washington RW, Knecht DA. Actin binding domains direct actin-binding proteins to different cytoskeletal locations. Bmc Cell Biology. 9: 10. PMID 18269770 DOI: 10.1186/1471-2121-9-10  0.764
2007 Lombardi ML, Knecht DA, Dembo M, Lee J. Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement. Journal of Cell Science. 120: 1624-34. PMID 17452624 DOI: 10.1242/Jcs.002527  0.316
2007 Hadjout N, Yin X, Knecht DA, Lynes MA. Automated real-time measurements of leukocyte chemotaxis. Journal of Immunological Methods. 320: 70-80. PMID 17275834 DOI: 10.1016/J.Jim.2006.12.005  0.318
2006 Woznica D, Knecht DA. Under-agarose chemotaxis of Dictyostelium discoideum. Methods in Molecular Biology (Clifton, N.J.). 346: 311-25. PMID 16957299 DOI: 10.1385/1-59745-144-4:311  0.355
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/Jcb.200412162  0.33
2004 Gao T, Knecht D, Tang L, Hatton RD, Gomer RH. A cell number counting factor regulates Akt/protein kinase B to regulate Dictyostelium discoideum group size. Eukaryotic Cell. 3: 1176-84. PMID 15470246 DOI: 10.1128/Ec.3.5.1176-1184.2004  0.404
2004 Thibodeau MS, Giardina C, Knecht DA, Helble J, Hubbard AK. Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 34-48. PMID 15056807 DOI: 10.1093/Toxsci/Kfh121  0.38
2003 Laevsky G, Knecht DA. Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments. Journal of Cell Science. 116: 3761-70. PMID 12890752 DOI: 10.1242/Jcs.00684  0.383
2003 Lee E, Seastone DJ, Harris E, Cardelli JA, Knecht DA. RacB regulates cytoskeletal function in Dictyostelium spp. Eukaryotic Cell. 2: 474-85. PMID 12796292 DOI: 10.1128/Ec.2.3.474-485.2003  0.417
2002 Gomer R, Gao T, Tang Y, Knecht D, Titus MA. Cell motility mediates tissue size regulation in Dictyostelium. Journal of Muscle Research and Cell Motility. 23: 809-15. PMID 12952079 DOI: 10.1023/A:1024487930787  0.407
2002 Olazabal IM, Caron E, May RC, Schilling K, Knecht DA, Machesky LM. Rho-kinase and myosin-II control phagocytic cup formation during CR, but not FcgammaR, phagocytosis. Current Biology : Cb. 12: 1413-18. PMID 12194823 DOI: 10.1016/S0960-9822(02)01069-2  0.341
2002 Lee E, Knecht DA. Visualization of actin dynamics during macropinocytosis and exocytosis. Traffic (Copenhagen, Denmark). 3: 186-92. PMID 11886589 DOI: 10.1034/J.1600-0854.2002.030304.X  0.313
2002 Maselli A, Laevsky G, Knecht DA. Kinetics of binding, uptake and degradation of live fluorescent (DsRed) bacteria by Dictyostelium discoideum. Microbiology (Reading, England). 148: 413-20. PMID 11832505 DOI: 10.1099/00221287-148-2-413  0.369
2001 Laevsky G, Knecht DA. Under-agarose folate chemotaxis of Dictyostelium discoideum amoebae in permissive and mechanically inhibited conditions. Biotechniques. 31: 1140-2, 1144, 1146-9. PMID 11730020 DOI: 10.2144/01315Rr03  0.398
2001 Hadjout N, Laevsky G, Knecht DA, Lynes MA. Automated real-time measurement of chemotactic cell motility. Biotechniques. 31: 1130-8. PMID 11730019 DOI: 10.2144/01315Rr02  0.351
2001 Rupper A, Lee K, Knecht D, Cardelli J. Sequential activities of phosphoinositide 3-kinase, PKB/Aakt, and Rab7 during macropinosome formation in Dictyostelium. Molecular Biology of the Cell. 12: 2813-24. PMID 11553719 DOI: 10.1091/Mbc.12.9.2813  0.404
2001 Lee E, Knecht DA. Cytoskeletal alterations in Dictyostelium induced by expression of human cdc42. European Journal of Cell Biology. 80: 399-409. PMID 11484931 DOI: 10.1078/0171-9335-00177  0.406
2001 Lee E, Pang K, Knecht D. The regulation of actin polymerization and cross-linking in Dictyostelium. Biochimica Et Biophysica Acta. 1525: 217-27. PMID 11257435 DOI: 10.1016/S0304-4165(01)00107-6  0.321
2001 Xu XS, Lee E, Chen T, Kuczmarski E, Chisholm RL, Knecht DA. During multicellular migration, myosin ii serves a structural role independent of its motor function. Developmental Biology. 232: 255-64. PMID 11254362 DOI: 10.1006/Dbio.2000.0132  0.383
2000 Palmieri SJ, Nebl T, Pope RK, Seastone DJ, Lee E, Hinchcliffe EH, Sluder G, Knecht D, Cardelli J, Luna EJ. Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton. Cell Motility and the Cytoskeleton. 46: 285-304. PMID 10962483 DOI: 10.1002/1097-0169(200008)46:4<285::Aid-Cm6>3.0.Co;2-N  0.388
2000 Ichetovkin I, Han J, Pang KM, Knecht DA, Condeelis JS. Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents. Cell Motility and the Cytoskeleton. 45: 293-306. PMID 10744862 DOI: 10.1002/(Sici)1097-0169(200004)45:4<293::Aid-Cm5>3.0.Co;2-1  0.312
1998 Seastone DJ, Lee E, Bush J, Knecht D, Cardelli J. Overexpression of a novel rho family GTPase, RacC, induces unusual actin-based structures and positively affects phagocytosis in Dictyostelium discoideum. Molecular Biology of the Cell. 9: 2891-904. PMID 9763450 DOI: 10.1091/Mbc.9.10.2891  0.44
1998 Pang KM, Lee E, Knecht DA. Use of a fusion protein between GFP and an actin-binding domain to visualize transient filamentous-actin structures. Current Biology : Cb. 8: 405-8. PMID 9545201 DOI: 10.1016/S0960-9822(98)70159-9  0.382
1998 Lee E, Shelden EA, Knecht DA. Formation of F-actin aggregates in cells treated with actin stabilizing drugs. Cell Motility and the Cytoskeleton. 39: 122-33. PMID 9484954 DOI: 10.1002/(Sici)1097-0169(1998)39:2<122::Aid-Cm3>3.0.Co;2-8  0.372
1998 Koonce MP, Knecht DA. Cytoplasmic dynein heavy chain is an essential gene product in Dictyostelium. Cell Motility and the Cytoskeleton. 39: 63-72. PMID 9453714 DOI: 10.1002/(Sici)1097-0169(1998)39:1<63::Aid-Cm6>3.0.Co;2-H  0.322
1997 Lee E, Shelden EA, Knecht DA. Changes in actin filament organization during pseudopod formation. Experimental Cell Research. 235: 295-9. PMID 9281379 DOI: 10.1006/Excr.1997.3665  0.322
1996 Shelden E, Knecht DA. Dictyostelium cell shape generation requires myosin II. Cell Motility and the Cytoskeleton. 35: 59-67. PMID 8874966 DOI: 10.1002/(Sici)1097-0169(1996)35:1<59::Aid-Cm5>3.0.Co;2-D  0.398
1996 Cohen NR, Knecht DA, Lodish HF. Functional expression of rat GLUT 1 glucose transporter in Dictyostelium discoideum. The Biochemical Journal. 315: 971-5. PMID 8645185 DOI: 10.1042/Bj3150971  0.432
1996 Xu XS, Kuspa A, Fuller D, Loomis WF, Knecht DA. Cell-cell adhesion prevents mutant cells lacking myosin II from penetrating aggregation streams of Dictyostelium. Developmental Biology. 175: 218-26. PMID 8626027 DOI: 10.1006/Dbio.1996.0109  0.58
1995 Knecht DA, Shelden E. Three-dimensional localization of wild-type and myosin II mutant cells during morphogenesis of Dictyostelium. Developmental Biology. 170: 434-44. PMID 7649374 DOI: 10.1006/Dbio.1995.1227  0.383
1993 Knecht D, Kern H, Scherczinger C. Bidirectional transcription from actin promoters in Dictyostelium. Biochimica Et Biophysica Acta. 1216: 105-9. PMID 8218397 DOI: 10.1016/0167-4781(93)90042-C  0.322
1992 Cox D, Condeelis J, Wessels D, Soll D, Kern H, Knecht DA. Targeted disruption of the ABP-120 gene leads to cells with altered motility. The Journal of Cell Biology. 116: 943-55. PMID 1310321 DOI: 10.1083/Jcb.116.4.943  0.404
1990 Knecht DA, Jung J, Matthews L. Quantification of transformation efficiency using a new method for clonal growth and selection of axenic Dictyostelium cells. Developmental Genetics. 11: 403-9. PMID 2096016 DOI: 10.1002/Dvg.1020110513  0.306
1988 Knecht DA, Loomis WF. Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum. Developmental Biology. 128: 178-84. PMID 3384173 DOI: 10.1016/0012-1606(88)90280-1  0.582
1988 Wessels D, Soll DR, Knecht D, Loomis WF, De Lozanne A, Spudich J. Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Developmental Biology. 128: 164-77. PMID 2838348 DOI: 10.1016/0012-1606(88)90279-5  0.596
1988 Peters DJ, Knecht DA, Loomis WF, De Lozanne A, Spudich J, Van Haastert PJ. Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain. Developmental Biology. 128: 158-63. PMID 2838347 DOI: 10.1016/0012-1606(88)90278-3  0.6
1987 Knecht DA, Loomis WF. Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science (New York, N.Y.). 236: 1081-6. PMID 3576221 DOI: 10.1126/Science.3576221  0.561
1987 Knecht DA, Fuller DL, Loomis WF. Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum. Developmental Biology. 121: 277-83. PMID 3569662 DOI: 10.1016/0012-1606(87)90160-6  0.549
1986 Cohen SM, Knecht D, Lodish HF, Loomis WF. DNA sequences required for expression of a Dictyostelium actin gene. The Embo Journal. 5: 3361-6. PMID 3028782 DOI: 10.1002/J.1460-2075.1986.Tb04651.X  0.595
1986 Knecht DA, Cohen SM, Loomis WF, Lodish HF. Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors. Molecular and Cellular Biology. 6: 3973-83. PMID 3025622 DOI: 10.1128/Mcb.6.11.3973  0.612
1986 Green ED, Knecht DA, Dimond RL. Examination of isoelectric focusing and electrophoretic methods for resolving acidic proteins Electrophoresis. 7: 407-413. DOI: 10.1002/Elps.1150070904  0.625
1985 Knecht DA, Green ED, Loomis WF, Dimond RL. Developmental changes in the modification of lysosomal enzymes in Dictyostelium discoideum. Developmental Biology. 107: 490-502. PMID 3918896 DOI: 10.1016/0012-1606(85)90330-6  0.711
1985 Cardelli JA, Knecht DA, Wunderlich R, Dimond RL. Major changes in gene expression occur during at least four stages of development of Dictyostelium discoideum. Developmental Biology. 110: 147-56. PMID 2408940 DOI: 10.1016/0012-1606(85)90072-7  0.649
1984 Knecht DA, Dimond RL, Wheeler S, Loomis WF. Antigenic determinants shared by lysosomal proteins of Dictyostelium discoideum. Characterization using monoclonal antibodies and isolation of mutations affecting the determinant. The Journal of Biological Chemistry. 259: 10633-40. PMID 6206057  0.692
1984 Knecht DA, Dimond RL. Visualization of antigenic proteins on Western blots. Analytical Biochemistry. 136: 180-4. PMID 6201085 DOI: 10.1016/0003-2697(84)90321-X  0.629
1983 Dimond RL, Knecht DA, Jordan KB, Burns RA, Livi GP. Secretory mutants in the cellular slime mold Dictyostelium discoideum. Methods in Enzymology. 96: 815-28. PMID 6656654 DOI: 10.1016/S0076-6879(83)96069-X  0.638
1983 Knecht DA, Mierendorf RC, Dimond RL. Immunological recognition of modifications on functionally related proteins. Methods in Enzymology. 98: 159-66. PMID 6199650 DOI: 10.1016/0076-6879(83)98146-6  0.642
1981 Cardelli JA, Knecht DA, Dimond RL. Membrane-bound and free polysomes in Dictyostelium discoideum. I. Isolation and developmental effects on size and distribution. Developmental Biology. 82: 180-5. PMID 7227633 DOI: 10.1016/0012-1606(81)90440-1  0.617
1981 Knecht DA, Dimond RL. Lysosomal enzymes possess a common antigenic determinant in the cellular slime mold, Dictyostelium discoideum. The Journal of Biological Chemistry. 256: 3564-75. PMID 6162850  0.613
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