| Year |
Citation |
Score |
| 2024 |
Woods KE, Akhter S, Rodriguez B, Townsend KA, Smith N, Smith B, Wambua A, Craddock V, Abisado-Duque RG, Santa EE, Manson DE, Oakley BR, Hancock LE, Miao Y, Blackwell HE, et al. Characterization of natural product inhibitors of quorum sensing reveals competitive inhibition of RhlR by -vanillin. Microbiology Spectrum. e0068124. PMID 39046261 DOI: 10.1128/spectrum.00681-24 |
0.408 |
|
| 2024 |
Eisenbraun EL, Vulpis TD, Prosser BN, Horswill AR, Blackwell HE. Synthetic Peptides Capable of Potent Multigroup Quorum Sensing Activation and Inhibition in Both Cultures and Biofilm Communities. Journal of the American Chemical Society. PMID 38832917 DOI: 10.1021/jacs.4c02694 |
0.366 |
|
| 2024 |
Woods KE, Akhter S, Rodriguez B, Townsend KA, Smith N, Smith B, Wambua A, Craddock V, Abisado-Duque RG, Santa EE, Manson DE, Oakley BR, Hancock LE, Miao Y, Blackwell HE, et al. Characterization of natural product inhibitors of quorum sensing in reveals competitive inhibition of RhlR by -vanillin. Biorxiv : the Preprint Server For Biology. PMID 38559250 DOI: 10.1101/2024.02.24.581676 |
0.408 |
|
| 2024 |
Manson DE, Ananiev GE, Guo S, Ericksen SS, Santa EE, Blackwell HE. Abiotic Small Molecule Inhibitors and Activators of the LasR Quorum Sensing Receptor in with Potencies Comparable or Surpassing -Acyl Homoserine Lactones. Acs Infectious Diseases. PMID 38506163 DOI: 10.1021/acsinfecdis.3c00593 |
0.384 |
|
| 2023 |
West KHJ, Ma SV, Pensinger DA, Tucholski T, Tiambeng TN, Eisenbraun EL, Yehuda A, Hayouka Z, Ge Y, Sauer JD, Blackwell HE. Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation in . Biochemistry. PMID 37699554 DOI: 10.1021/acs.biochem.3c00373 |
0.38 |
|
| 2023 |
Zhang Q, Linke V, Overmyer KA, Traeger LL, Kasahara K, Miller IJ, Manson DE, Polaske TJ, Kerby RL, Kemis JH, Trujillo EA, Reddy TR, Russell JD, Schueler KL, Stapleton DS, ... ... Blackwell HE, et al. Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut. Nature Microbiology. PMID 36973420 DOI: 10.1038/s41564-023-01366-2 |
0.761 |
|
| 2023 |
Zhang Q, Linke V, Overmyer KA, Traeger LL, Kasahara K, Miller IJ, Manson DE, Polaske TJ, Kerby RL, Kemis JH, Trujillo EA, Reddy TR, Russell JD, Schueler KL, Stapleton DS, ... ... Blackwell HE, et al. Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut. Nature Microbiology. PMID 36759753 DOI: 10.1038/s41564-023-01326-w |
0.78 |
|
| 2022 |
Gahan CG, Van Lehn RC, Blackwell HE, Lynn DM. Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Membrane Composition on Membrane Remodeling. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 36534123 DOI: 10.1021/acs.langmuir.2c02506 |
0.492 |
|
| 2022 |
Nyffeler KE, Santa EE, Blackwell HE. Small Molecules with Either Receptor-Selective or Pan-Receptor Activity in the Three LuxR-Type Receptors that Regulate Quorum Sensing in . Acs Chemical Biology. 17: 2979-2985. PMID 36239990 DOI: 10.1021/acschembio.2c00675 |
0.377 |
|
| 2022 |
Agarwal H, Quinn LJ, Walter SC, Polaske TJ, Chang DH, Palecek SP, Blackwell HE, Lynn DM. Slippery Antifouling Polymer Coatings Fabricated Entirely from Biodegradable and Biocompatible Components. Acs Applied Materials & Interfaces. 14: 17940-17949. PMID 35394750 DOI: 10.1021/acsami.1c25218 |
0.484 |
|
| 2022 |
West KHJ, Gahan CG, Kierski PR, Calderon DF, Zhao K, Czuprynski CJ, McAnulty JF, Lynn DM, Blackwell HE. Sustained Release of a Synthetic Autoinducing Peptide Mimetic Blocks Bacterial Communication and Virulence In Vivo. Angewandte Chemie (International Ed. in English). e202201798. PMID 35334139 DOI: 10.1002/anie.202201798 |
0.543 |
|
| 2021 |
Polaske TJ, Gahan CG, Nyffeler KE, Lynn DM, Blackwell HE. Identification of small molecules that strongly inhibit bacterial quorum sensing using a high-throughput lipid vesicle lysis assay. Cell Chemical Biology. PMID 34932995 DOI: 10.1016/j.chembiol.2021.12.005 |
0.608 |
|
| 2021 |
Agarwal H, Polaske TJ, Sánchez-Velázquez G, Blackwell HE, Lynn DM. Slippery nanoemulsion-infused porous surfaces (SNIPS): anti-fouling coatings that can host and sustain the release of water-soluble agents. Chemical Communications (Cambridge, England). 57: 12691-12694. PMID 34781330 DOI: 10.1039/d1cc04645d |
0.488 |
|
| 2021 |
Agarwal H, Nyffeler KE, Blackwell HE, Lynn DM. Fabrication of Slippery Liquid-Infused Coatings in Flexible Narrow-Bore Tubing. Acs Applied Materials & Interfaces. 13: 55621-55632. PMID 34775755 DOI: 10.1021/acsami.1c14662 |
0.473 |
|
| 2021 |
Gahan CG, Van Lehn RC, Blackwell HE, Lynn DM. Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Acyl Tail Structure on Multiscale Response. Langmuir : the Acs Journal of Surfaces and Colloids. 37: 12049-12058. PMID 34606725 DOI: 10.1021/acs.langmuir.1c01825 |
0.538 |
|
| 2021 |
Gahan CG, Patel SJ, Chen LM, Manson DE, Ehmer ZJ, Blackwell HE, Van Lehn RC, Lynn DM. Bacterial Quorum Sensing Signals Promote Large-Scale Remodeling of Lipid Membranes. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 34283628 DOI: 10.1021/acs.langmuir.1c01204 |
0.797 |
|
| 2021 |
Agarwal H, Nyffeler KE, Manna U, Blackwell HE, Lynn DM. Liquid Crystal-Infused Porous Polymer Surfaces: A "Slippery" Soft Material Platform for the Naked-Eye Detection and Discrimination of Amphiphilic Species. Acs Applied Materials & Interfaces. PMID 34236833 DOI: 10.1021/acsami.1c08170 |
0.485 |
|
| 2021 |
West KHJ, Shen W, Eisenbraun EL, Yang T, Vasquez JK, Horswill AR, Blackwell HE. Non-Native Peptides Capable of Pan-Activating the Quorum Sensing System across Multiple Specificity Groups of . Acs Chemical Biology. PMID 33988969 DOI: 10.1021/acschembio.1c00240 |
0.339 |
|
| 2020 |
Styles MJ, Early SA, Tucholski T, West KHJ, Ge Y, Blackwell HE. Chemical Control of Quorum Sensing in : Identification of Small Molecule Modulators of SdiA and Mechanistic Characterization of a Covalent Inhibitor. Acs Infectious Diseases. PMID 33124430 DOI: 10.1021/acsinfecdis.0c00654 |
0.398 |
|
| 2020 |
Ortiz BJ, Boursier ME, Barrett KL, Manson DE, Amador-Noguez D, Abbott NL, Blackwell HE, Lynn DM. Liquid Crystal Emulsions that Intercept and Report on Bacterial Quorum Sensing. Acs Applied Materials & Interfaces. PMID 32484648 DOI: 10.1021/Acsami.0C05792 |
0.81 |
|
| 2020 |
Gahan CG, Patel SJ, Boursier ME, Nyffeler KE, Jennings J, Abbott NL, Blackwell HE, Van Lehn RC, Lynn DM. Bacterial Quorum Sensing Signals Self-Assemble in Aqueous Media to Form Micelles and Vesicles: An Integrated Experimental and Molecular Dynamics Study. The Journal of Physical Chemistry. B. PMID 32271573 DOI: 10.1021/Acs.Jpcb.0C00496 |
0.568 |
|
| 2020 |
Manson DE, O'Reilly MC, Nyffeler KE, Blackwell HE. Design, Synthesis, and Biochemical Characterization of Non-Native Antagonists of the Quorum Sensing Receptor LasR with Nanomolar IC Values. Acs Infectious Diseases. PMID 32037806 DOI: 10.1021/Acsinfecdis.9B00518 |
0.829 |
|
| 2019 |
Vasquez JK, West KHJ, Yang T, Polaske TJ, Cornilescu G, Tonelli M, Blackwell HE. Conformational Switch to a β-turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency. Journal of the American Chemical Society. PMID 31859506 DOI: 10.1021/Jacs.9B05513 |
0.457 |
|
| 2019 |
Shin D, Gorgulla C, Boursier ME, Rexrode N, Brown EC, Arthanari H, Blackwell HE, Nagarajan R. N-Acyl homoserine lactone analog modulators of the Pseudomonas aeruginosa RhlI quorum sensing signal synthase. Acs Chemical Biology. PMID 31545595 DOI: 10.1021/Acschembio.9B00671 |
0.442 |
|
| 2019 |
Slinger BL, Deay JJ, Chandler JR, Blackwell HE. Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands. Scientific Reports. 9: 13449. PMID 31530834 DOI: 10.1038/S41598-019-49693-X |
0.45 |
|
| 2019 |
Vasquez JK, Blackwell HE. Simplified Autoinducing Peptide Mimetics with Single-Nanomolar Activity Against the Staphylococcus aureus AgrC Quorum Sensing Receptor. Acs Infectious Diseases. PMID 30817121 DOI: 10.1021/Acsinfecdis.9B00002 |
0.443 |
|
| 2019 |
Boursier ME, Combs JB, Blackwell HE. N-Acyl L-homocysteine thiolactones are potent and stable synthetic modulators of the RhlR quorum sensing receptor in Pseudomonas aeruginosa. Acs Chemical Biology. PMID 30668907 DOI: 10.1021/Acschembio.8B01079 |
0.476 |
|
| 2018 |
Styles MJ, Blackwell HE. Non-native autoinducer analogs capable of modulating the SdiA quorum sensing receptor in serovar Typhimurium. Beilstein Journal of Organic Chemistry. 14: 2651-2664. PMID 30410627 DOI: 10.3762/Bjoc.14.243 |
0.5 |
|
| 2018 |
Palmer AG, Senechal AC, Haire TC, Mehta NP, Valiquette SD, Blackwell HE. Selection of appropriate autoinducer analogs for the modulation of quorum sensing at the host-bacteria interface. Acs Chemical Biology. PMID 30296049 DOI: 10.1021/Acschembio.8B00676 |
0.821 |
|
| 2018 |
Boursier ME, Moore JD, Heitman KM, Shepardson-Fungairino SP, Combs JB, Koenig LC, Shin D, Brown EC, Nagarajan R, Blackwell HE. Structure-function analyses of the N-butanoyl L-homoserine lactone quorum-sensing signal define features critical to activity in RhlR. Acs Chemical Biology. PMID 30114353 DOI: 10.1021/Acschembio.8B00577 |
0.745 |
|
| 2018 |
O'Reilly MC, Dong SH, Rossi FM, Karlen KM, Kumar RS, Nair SK, Blackwell HE. Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR. Cell Chemical Biology. PMID 30033130 DOI: 10.1016/J.Chembiol.2018.06.007 |
0.417 |
|
| 2018 |
Boursier ME, Manson DE, Combs JB, Blackwell HE. A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence. Bioorganic & Medicinal Chemistry. PMID 29793752 DOI: 10.1016/J.Bmc.2018.05.018 |
0.828 |
|
| 2018 |
Mooney JA, Pridgen EM, Manasherob R, Suh G, Blackwell HE, Barron AE, Bollyky PL, Goodman SB, Amanatullah DF. Implant-Associated Bacterial Biofilm and Quorum Sensing in Periprosthetic Joint Infections. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29663554 DOI: 10.1002/Jor.24019 |
0.347 |
|
| 2018 |
Wysoczynski-Horita CL, Boursier ME, Hill R, Hansen K, Blackwell HE, Churchill MEA. Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands. Molecular Microbiology. PMID 29437248 DOI: 10.1111/Mmi.13930 |
0.454 |
|
| 2017 |
Schneider A, Fritz D, Vasquez JK, Vollrath S, Blackwell HE, Brase PS. Microwave-Facilitated SPOT-Synthesis of Antibacterial Dipeptoids. Acs Combinatorial Science. PMID 29035557 DOI: 10.1021/Acscombsci.7B00096 |
0.362 |
|
| 2017 |
Gerdt JP, Wittenwyler DM, Combs JB, Boursier ME, Brummond JW, Xu H, Blackwell HE. Chemical interrogation of LuxR-type quorum sensing receptors reveals new insights into receptor selectivity and the potential for interspecies bacterial signaling. Acs Chemical Biology. PMID 28829573 DOI: 10.1021/Acschembio.7B00458 |
0.797 |
|
| 2017 |
Kratochvil MJ, Yang T, Blackwell HE, Lynn DM. Non-Woven Polymer Nanofiber Coatings that Inhibit Quorum Sensing in Staphylococcus aureus: Toward New Non-Bactericidal Approaches to Infection Control. Acs Infectious Diseases. PMID 28118541 DOI: 10.1021/Acsinfecdis.6B00173 |
0.618 |
|
| 2016 |
Manna U, Raman N, Welsh MA, Zayas-Gonzalez YM, Blackwell HE, Palecek SP, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Microbial Surface Fouling and Kill Non-Adherent Pathogens in Surrounding Media: A Controlled Release Approach. Advanced Functional Materials. 26: 3599-3611. PMID 28713229 DOI: 10.1002/Adfm.201505522 |
0.586 |
|
| 2016 |
Vasquez JK, Tal-Gan Y, Cornilescu G, Tyler KA, Blackwell HE. Simplified AIP-II Peptidomimetics are Potent Inhibitors of Staphylococcus aureus AgrC Quorum Sensing Receptors. Chembiochem : a European Journal of Chemical Biology. PMID 28006082 DOI: 10.1002/Cbic.201600516 |
0.71 |
|
| 2016 |
Palmer AG, Mukherjee A, Stacy DM, Lazar S, Ané JM, Blackwell HE. Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume-Rhizobia Symbiosis. Chembiochem : a European Journal of Chemical Biology. PMID 27739645 DOI: 10.1002/Cbic.201600373 |
0.824 |
|
| 2016 |
Patel NM, Moore JD, Blackwell HE, Amador-Noguez D. Identification of Unanticipated and Novel N-Acyl L-Homoserine Lactones (AHLs) Using a Sensitive Non-Targeted LC-MS/MS Method. Plos One. 11: e0163469. PMID 27706219 DOI: 10.1371/Journal.Pone.0163469 |
0.651 |
|
| 2016 |
Kratochvil MJ, Welsh MA, Manna U, Ortiz BJ, Blackwell HE, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Bacterial Surface Fouling and Inhibit Virulence Phenotypes in Surrounding Planktonic Cells. Acs Infectious Diseases. 2: 509-517. PMID 27626103 DOI: 10.1021/Acsinfecdis.6B00065 |
0.595 |
|
| 2016 |
Tal-Gan Y, Ivancic M, Cornilescu G, Yang T, Blackwell HE. Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus. Angewandte Chemie (International Ed. in English). PMID 27276693 DOI: 10.1002/Anie.201602974 |
0.745 |
|
| 2016 |
Welsh MA, Blackwell HE. Chemical probes of quorum sensing: from compound development to biological discovery. Fems Microbiology Reviews. PMID 27268906 DOI: 10.1093/Femsre/Fuw009 |
0.465 |
|
| 2016 |
Yang T, Tal-Gan Y, Paharik AE, Horswill AR, Blackwell HE. Structure-Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation. Acs Chemical Biology. PMID 27159024 DOI: 10.1021/Acschembio.6B00120 |
0.73 |
|
| 2016 |
Welsh MA, Blackwell HE. Chemical Genetics Reveals Environment-Specific Roles for Quorum Sensing Circuits in Pseudomonas aeruginosa. Cell Chemical Biology. PMID 26905657 DOI: 10.1016/J.Chembiol.2016.01.006 |
0.412 |
|
| 2016 |
O'Reilly MC, Blackwell HE. Structure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor. Acs Infectious Diseases. 2: 32-38. PMID 26807436 DOI: 10.1021/Acsinfecdis.5B00112 |
0.464 |
|
| 2015 |
Kratochvil MJ, Tal-Gan Y, Yang T, Blackwell HE, Lynn DM. Nanoporous Superhydrophobic Coatings that Promote the Extended Release of Water-Labile Quorum Sensing Inhibitors and Enable Long-Term Modulation of Quorum Sensing in Staphylococcus aureus. Acs Biomaterials Science & Engineering. 1: 1039-1049. PMID 26501126 DOI: 10.1021/Acsbiomaterials.5B00313 |
0.727 |
|
| 2015 |
Moore JD, Rossi FM, Welsh MA, Nyffeler KE, Blackwell HE. A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design. Journal of the American Chemical Society. PMID 26491787 DOI: 10.1021/Jacs.5B06728 |
0.737 |
|
| 2015 |
Eibergen NR, Moore JD, Mattmann ME, Blackwell HE. Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa. Chembiochem : a European Journal of Chemical Biology. 16: 2348-56. PMID 26460240 DOI: 10.1002/Cbic.201500357 |
0.819 |
|
| 2015 |
Tal-Gan Y, Ivancic M, Cornilescu G, Blackwell HE. Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus. Organic & Biomolecular Chemistry. PMID 26416476 DOI: 10.1039/C5Ob01735A |
0.731 |
|
| 2015 |
Welsh MA, Eibergen NR, Moore JD, Blackwell HE. Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes. Journal of the American Chemical Society. 137: 1510-9. PMID 25574853 DOI: 10.1021/Ja5110798 |
0.828 |
|
| 2015 |
Gerdt JP, McInnis CE, Schell TL, Blackwell HE. Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR. Organic & Biomolecular Chemistry. 13: 1453-62. PMID 25474181 DOI: 10.1039/C4Ob02252A |
0.83 |
|
| 2014 |
Gerdt JP, McInnis CE, Schell TL, Rossi FM, Blackwell HE. Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands. Chemistry & Biology. 21: 1361-9. PMID 25242287 DOI: 10.1016/J.Chembiol.2014.08.008 |
0.82 |
|
| 2014 |
Gerdt JP, Blackwell HE. Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria. Acs Chemical Biology. 9: 2291-9. PMID 25105594 DOI: 10.1021/Cb5004288 |
0.766 |
|
| 2014 |
Palmer AG, Senechal AC, Mukherjee A, Ané JM, Blackwell HE. Plant responses to bacterial N-acyl L-homoserine lactones are dependent on enzymatic degradation to L-homoserine. Acs Chemical Biology. 9: 1834-45. PMID 24918118 DOI: 10.1021/Cb500191A |
0.603 |
|
| 2014 |
Tal-Gan Y, Stacy DM, Blackwell HE. N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus aureus. Chemical Communications (Cambridge, England). 50: 3000-3. PMID 24509706 DOI: 10.1039/C4Cc00117F |
0.809 |
|
| 2014 |
Moore JD, Gerdt JP, Eibergen NR, Blackwell HE. Active efflux influences the potency of quorum sensing inhibitors in Pseudomonas aeruginosa. Chembiochem : a European Journal of Chemical Biology. 15: 435-42. PMID 24478193 DOI: 10.1002/Cbic.201300701 |
0.825 |
|
| 2014 |
McInnis CE, Blackwell HE. Non-native N-aroyl L-homoserine lactones are potent modulators of the quorum sensing receptor RpaR in Rhodopseudomonas palustris. Chembiochem : a European Journal of Chemical Biology. 15: 87-93. PMID 24281952 DOI: 10.1002/Cbic.201300570 |
0.755 |
|
| 2014 |
Studer SV, Schwartzman JA, Ho JS, Geske GD, Blackwell HE, Ruby EG. Non-native acylated homoserine lactones reveal that LuxIR quorum sensing promotes symbiont stability. Environmental Microbiology. 16: 2623-34. PMID 24191970 DOI: 10.1111/1462-2920.12322 |
0.801 |
|
| 2014 |
Broderick AH, Stacy DM, Tal-Gan Y, Kratochvil MJ, Blackwell HE, Lynn DM. Surface coatings that promote rapid release of peptide-based AgrC inhibitors for attenuation of quorum sensing in Staphylococcus aureus. Advanced Healthcare Materials. 3: 97-105. PMID 23813683 DOI: 10.1002/Adhm.201300119 |
0.802 |
|
| 2014 |
Moore JD, Gerdt JP, Eibergen NR, Blackwell HE. Corrigendum: Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa Chembiochem. 15: 634-634. DOI: 10.1002/Cbic.201400080 |
0.786 |
|
| 2013 |
Tal-Gan Y, Ivancic M, Cornilescu G, Cornilescu CC, Blackwell HE. Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. Journal of the American Chemical Society. 135: 18436-44. PMID 24219181 DOI: 10.1021/Ja407533E |
0.735 |
|
| 2013 |
Tal-Gan Y, Stacy DM, Foegen MK, Koenig DW, Blackwell HE. Highly potent inhibitors of quorum sensing in Staphylococcus aureus revealed through a systematic synthetic study of the group-III autoinducing peptide. Journal of the American Chemical Society. 135: 7869-82. PMID 23647400 DOI: 10.1021/Ja3112115 |
0.815 |
|
| 2013 |
Crapster JA, Guzei IA, Blackwell HE. A peptoid ribbon secondary structure Angewandte Chemie - International Edition. 52: 5079-5084. PMID 23576308 DOI: 10.1002/Anie.201208630 |
0.344 |
|
| 2013 |
Broderick AH, Breitbach AS, Frei R, Blackwell HE, Lynn DM. Surface-mediated release of a small-molecule modulator of bacterial biofilm formation: a non-bactericidal approach to inhibiting biofilm formation in Pseudomonas aeruginosa. Advanced Healthcare Materials. 2: 993-1000. PMID 23335593 DOI: 10.1002/Adhm.201200334 |
0.8 |
|
| 2013 |
Stacy DM, Le Quement ST, Hansen CL, Clausen JW, Tolker-Nielsen T, Brummond JW, Givskov M, Nielsen TE, Blackwell HE. Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators. Organic & Biomolecular Chemistry. 11: 938-54. PMID 23258305 DOI: 10.1039/C2Ob27155A |
0.848 |
|
| 2013 |
Tal-Gan Y, Ivancic M, Cornilescu G, Cornilescu C, Blackwell H. AIP-III_F5A cyclic peptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr21039 |
0.642 |
|
| 2012 |
Frei R, Breitbach AS, Blackwell HE. Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing. Chemical Science (Royal Society of Chemistry : 2010). 3: 1555-1561. PMID 23198087 DOI: 10.1039/C2Sc01089E |
0.814 |
|
| 2012 |
Praneenararat T, Palmer AG, Blackwell HE. Chemical methods to interrogate bacterial quorum sensing pathways. Organic & Biomolecular Chemistry. 10: 8189-99. PMID 22948815 DOI: 10.1039/C2Ob26353J |
0.626 |
|
| 2012 |
Stacy DM, Welsh MA, Rather PN, Blackwell HE. Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones. Acs Chemical Biology. 7: 1719-28. PMID 22853441 DOI: 10.1021/Cb300351X |
0.82 |
|
| 2012 |
Frei R, Breitbach AS, Blackwell HE. 2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms. Angewandte Chemie (International Ed. in English). 51: 5226-9. PMID 22488868 DOI: 10.1002/Anie.201109258 |
0.806 |
|
| 2011 |
Crapster JA, Stringer JR, Guzei IA, Blackwell HE. Design and conformational analysis of peptoids containing N-hydroxy amides reveals a unique sheet-like secondary structure. Biopolymers. 96: 604-16. PMID 22180908 DOI: 10.1002/Bip.21599 |
0.673 |
|
| 2011 |
Lindemann A, Pessi G, Schaefer AL, Mattmann ME, Christensen QH, Kessler A, Hennecke H, Blackwell HE, Greenberg EP, Harwood CS. Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. Proceedings of the National Academy of Sciences of the United States of America. 108: 16765-70. PMID 21949379 DOI: 10.1073/Pnas.1114125108 |
0.738 |
|
| 2011 |
Palmer AG, Streng E, Blackwell HE. Attenuation of virulence in pathogenic bacteria using synthetic quorum-sensing modulators under native conditions on plant hosts. Acs Chemical Biology. 6: 1348-56. PMID 21932837 DOI: 10.1021/Cb200298G |
0.638 |
|
| 2011 |
Stringer JR, Crapster JA, Guzei IA, Blackwell HE. Extraordinarily robust polyproline type I peptoid helices generated via the incorporation of α-chiral aromatic N-1-naphthylethyl side chains. Journal of the American Chemical Society. 133: 15559-67. PMID 21861531 DOI: 10.1021/Ja204755P |
0.669 |
|
| 2011 |
McInnis CE, Blackwell HE. Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing. Bioorganic & Medicinal Chemistry. 19: 4812-9. PMID 21798749 DOI: 10.1016/J.Bmc.2011.06.072 |
0.772 |
|
| 2011 |
McInnis CE, Blackwell HE. Thiolactone modulators of quorum sensing revealed through library design and screening. Bioorganic & Medicinal Chemistry. 19: 4820-8. PMID 21798746 DOI: 10.1016/J.Bmc.2011.06.071 |
0.783 |
|
| 2011 |
Praneenararat T, Beary TMJ, Breitbach AS, Blackwell HE. Synthesis and application of an N-acylated l-homoserine lactone derivatized affinity matrix for the isolation of quorum sensing signal receptors Bioorganic and Medicinal Chemistry Letters. 21: 5054-5057. PMID 21592793 DOI: 10.1016/J.Bmcl.2011.04.062 |
0.785 |
|
| 2011 |
Mattmann ME, Shipway PM, Heth NJ, Blackwell HE. Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones. Chembiochem : a European Journal of Chemical Biology. 12: 942-9. PMID 21365734 DOI: 10.1002/Cbic.201000708 |
0.8 |
|
| 2011 |
Blackwell HE, Fuqua C. Introduction to bacterial signals and chemical communication Chemical Reviews. 111: 1-3. PMID 21222491 DOI: 10.1021/Cr100407J |
0.328 |
|
| 2011 |
Stringer JR, Bowman MD, Weisblum B, Blackwell HE. Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones. Acs Combinatorial Science. 13: 175-80. PMID 21210707 DOI: 10.1021/Co100053P |
0.769 |
|
| 2011 |
Palmer AG, Streng E, Jewell KA, Blackwell HE. Quorum sensing in bacterial species that use degenerate autoinducers can be tuned by using structurally identical non-native ligands. Chembiochem : a European Journal of Chemical Biology. 12: 138-47. PMID 21154995 DOI: 10.1002/Cbic.201000551 |
0.673 |
|
| 2011 |
Breitbach AS, Broderick AH, Jewell CM, Gunasekaran S, Lin Q, Lynn DM, Blackwell HE. Surface-mediated release of a synthetic small-molecule modulator of bacterial quorum sensing: gradual release enhances activity. Chemical Communications (Cambridge, England). 47: 370-2. PMID 20830354 DOI: 10.1039/C0Cc02316G |
0.795 |
|
| 2011 |
Stringer JR, Bowman MD, Weisblum B, Blackwell HE. Correction to Improved Small-Molecule Macroarray Platform for the Rapid Synthesis and Discovery of Antibacterial Chalcones Acs Combinatorial Science. 13: 345-345. DOI: 10.1021/Co2000345 |
0.661 |
|
| 2010 |
Borlee BR, Geske GD, Blackwell HE, Handelsman J. Identification of synthetic inducers and inhibitors of the quorum-sensing regulator LasR in Pseudomonas aeruginosa by high-throughput screening. Applied and Environmental Microbiology. 76: 8255-8. PMID 20935125 DOI: 10.1128/Aem.00499-10 |
0.787 |
|
| 2010 |
Stringer JR, Crapster JA, Guzei IA, Blackwell HE. Construction of peptoids with all trans-amide backbones and peptoid reverse turns via the tactical incorporation of N-aryl side chains capable of hydrogen bonding. The Journal of Organic Chemistry. 75: 6068-78. PMID 20722367 DOI: 10.1021/Jo101075A |
0.672 |
|
| 2010 |
Mattmann ME, Blackwell HE. Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa. The Journal of Organic Chemistry. 75: 6737-46. PMID 20672805 DOI: 10.1021/Jo101237E |
0.786 |
|
| 2010 |
Frei R, Blackwell HE. Small molecule macroarray construction via palladium-mediated carbon-carbon bond-forming reactions: highly efficient synthesis and screening of stilbene arrays. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 2692-5. PMID 20135652 DOI: 10.1002/Chem.200903445 |
0.606 |
|
| 2010 |
Blackwell HE, Sadowsky JD, Howard RJ, Sampson JN, Chao JA, Steinmetz WE, O'Leary DJ, Grubbs RH. ChemInform Abstract: Ring-Closing Metathesis of Olefinic Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides. Cheminform. 32: no-no. DOI: 10.1002/chin.200146206 |
0.379 |
|
| 2010 |
Blackwell HE, O'Leary DJ, Chatterjee AK, Washenfelder RA, Bussmann DA, Grubbs RH. ChemInform Abstract: New Approaches to Olefin Cross-Metathesis. Cheminform. 31: no-no. DOI: 10.1002/chin.200015061 |
0.536 |
|
| 2010 |
MILLER SJ, BLACKWELL HE, GRUBBS RH. ChemInform Abstract: Application of Ring-Closing Metathesis to the Synthesis of Rigidified Amino Acids and Peptides. Cheminform. 28: no-no. DOI: 10.1002/chin.199707217 |
0.352 |
|
| 2009 |
Campbell J, Lin Q, Geske GD, Blackwell HE. New and unexpected insights into the modulation of LuxR-type quorum sensing by cyclic dipeptides. Acs Chemical Biology. 4: 1051-9. PMID 19928886 DOI: 10.1021/Cb900165Y |
0.835 |
|
| 2009 |
Gorske BC, Stringer JR, Bastian BL, Fowler SA, Blackwell HE. New strategies for the design of folded peptoids revealed by a survey of noncovalent interactions in model systems. Journal of the American Chemical Society. 131: 16555-67. PMID 19860427 DOI: 10.1021/Ja907184G |
0.791 |
|
| 2009 |
Campbell J, Blackwell HE. Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeri. Journal of Combinatorial Chemistry. 11: 1094-9. PMID 19831384 DOI: 10.1021/Cc900115X |
0.593 |
|
| 2009 |
Praneenararat T, Geske GD, Blackwell HE. Efficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarrays. Organic Letters. 11: 4600-3. PMID 19743816 DOI: 10.1021/Ol901871Y |
0.788 |
|
| 2009 |
Buck ME, Breitbach AS, Belgrade SK, Blackwell HE, Lynn DM. Chemical modification of reactive multilayered films fabricated from poly(2-alkenyl azlactone)s: design of surfaces that prevent or promote mammalian cell adhesion and bacterial biofilm growth. Biomacromolecules. 10: 1564-74. PMID 19438231 DOI: 10.1021/Bm9001552 |
0.778 |
|
| 2009 |
Fowler SA, Blackwell HE. Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function. Organic & Biomolecular Chemistry. 7: 1508-24. PMID 19343235 DOI: 10.1039/B817980H |
0.559 |
|
| 2009 |
Fowler SA, Luechapanichkul R, Blackwell HE. Synthesis and characterization of nitroaromatic peptoids: fine tuning peptoid secondary structure through monomer position and functionality. The Journal of Organic Chemistry. 74: 1440-9. PMID 19159244 DOI: 10.1021/Jo8023363 |
0.596 |
|
| 2008 |
Geske GD, Mattmann ME, Blackwell HE. Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorganic & Medicinal Chemistry Letters. 18: 5978-81. PMID 18760602 DOI: 10.1016/J.Bmcl.2008.07.089 |
0.811 |
|
| 2008 |
Borlee BR, Geske GD, Robinson CJ, Blackwell HE, Handelsman J. Quorum-sensing signals in the microbial community of the cabbage white butterfly larval midgut. The Isme Journal. 2: 1101-11. PMID 18650927 DOI: 10.1038/Ismej.2008.70 |
0.789 |
|
| 2008 |
Palmer AG, Blackwell HE. Deciphering a protolanguage for bacteria-host communication. Nature Chemical Biology. 4: 452-4. PMID 18641623 DOI: 10.1038/Nchembio0808-452 |
0.59 |
|
| 2008 |
Geske GD, O'Neill JC, Blackwell HE. Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chemical Society Reviews. 37: 1432-47. PMID 18568169 DOI: 10.1039/B703021P |
0.81 |
|
| 2008 |
Fowler SA, Stacy DM, Blackwell HE. Design and synthesis of macrocyclic peptomers as mimics of a quorum sensing signal from Staphylococcus aureus. Organic Letters. 10: 2329-32. PMID 18476747 DOI: 10.1021/Ol800908H |
0.812 |
|
| 2008 |
Geske GD, O'Neill JC, Miller DM, Wezeman RJ, Mattmann ME, Lin Q, Blackwell HE. Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing. Chembiochem : a European Journal of Chemical Biology. 9: 389-400. PMID 18224645 DOI: 10.1002/Cbic.200700551 |
0.824 |
|
| 2008 |
Mattmann ME, Geske GD, Worzalla GA, Chandler JR, Sappington KJ, Greenberg EP, Blackwell HE. Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry Letters. 18: 3072-5. PMID 18083553 DOI: 10.1016/J.Bmcl.2007.11.095 |
0.821 |
|
| 2007 |
O'Neill JC, Blackwell HE. Solid-phase and microwave-assisted syntheses of 2,5-diketopiperazines: Small molecules with great potential Combinatorial Chemistry and High Throughput Screening. 10: 857-876. PMID 18288948 DOI: 10.2174/138620707783220365 |
0.362 |
|
| 2007 |
Geske GD, O'Neill JC, Miller DM, Mattmann ME, Blackwell HE. Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action. Journal of the American Chemical Society. 129: 13613-25. PMID 17927181 DOI: 10.1021/Ja074135H |
0.82 |
|
| 2007 |
Gorske BC, Bastian BL, Geske GD, Blackwell HE. Local and tunable n-->pi* interactions regulate amide isomerism in the peptoid backbone. Journal of the American Chemical Society. 129: 8928-9. PMID 17608423 DOI: 10.1021/Ja071310L |
0.777 |
|
| 2007 |
Geske GD, O'Neill JC, Blackwell HE. N-phenylacetanoyl-L-homoserine lactones can strongly antagonize or superagonize quorum sensing in Vibrio fischeri. Acs Chemical Biology. 2: 315-9. PMID 17480049 DOI: 10.1021/Cb700036X |
0.804 |
|
| 2007 |
Bowman MD, O'Neill JC, Stringer JR, Blackwell HE. Rapid identification of antibacterial agents effective against Staphylococcus aureus using small-molecule macroarrays. Chemistry & Biology. 14: 351-7. PMID 17462570 DOI: 10.1016/J.Chembiol.2007.03.006 |
0.764 |
|
| 2007 |
Chan YY, Bian HS, Tan TM, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL. Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump. Journal of Bacteriology. 189: 4320-4. PMID 17384185 DOI: 10.1128/Jb.00003-07 |
0.777 |
|
| 2007 |
Guzei IA, Spencer LC, Lin Q, Blackwell HE. N-{(Aminocarbonyl)[(S)-4-nitrobenzyl]methyl}-N-{[(R)-cyclohexyl] (cyclohexylaminocarbonyl)methyl}propanamide methanol solvate Acta Crystallographica Section E: Structure Reports Online. 63: o1892-o1894. DOI: 10.1107/S1600536807012299 |
0.431 |
|
| 2006 |
Gorske BC, Blackwell HE. Tuning peptoid secondary structure with pentafluoroaromatic functionality: A new design paradigm for the construction of discretely folded peptoid structures Journal of the American Chemical Society. 128: 14378-14387. PMID 17076512 DOI: 10.1021/Ja065248O |
0.8 |
|
| 2006 |
Lin Q, Blackwell HE. Rapid synthesis of diketopiperazine macroarrays via Ugi four-component reactions on planar solid supports Chemical Communications. 2884-2886. PMID 17007405 DOI: 10.1039/B604329A |
0.462 |
|
| 2006 |
Blackwell HE. Hitting the SPOT: small-molecule macroarrays advance combinatorial synthesis Current Opinion in Chemical Biology. 10: 203-212. PMID 16682247 DOI: 10.1016/J.Cbpa.2006.04.026 |
0.366 |
|
| 2006 |
Guzei IA, Gorske BC, Blackwell HE. N-[1-(pentafluorophenyl)ethyl]acetamide Acta Crystallographica Section C: Crystal Structure Communications. 62: o286-o288. PMID 16679606 DOI: 10.1107/S0108270106012121 |
0.777 |
|
| 2006 |
Gorske BC, Blackwell HE. Interception of quorum sensing in Staphylococcus aureus: A new niche for peptidomimetics Organic and Biomolecular Chemistry. 4: 1441-1445. PMID 16604206 DOI: 10.1039/B517681F |
0.808 |
|
| 2006 |
Bowman MD, Jacobson MM, Blackwell HE. Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays. Organic Letters. 8: 1645-8. PMID 16597131 DOI: 10.1021/Ol0602708 |
0.562 |
|
| 2006 |
Blackwell H, Lin Q. Rapid Synthesis of Diketopiperazine Macroarrays Synfacts. 2006: 1073-1073. DOI: 10.1055/S-2006-949299 |
0.434 |
|
| 2006 |
Hollenbeck JJ, Wixson EN, Geske GD, Dodge MW, Tseng TA, Clauss AD, Blackwell HE. A new model for transitioning students from the undergraduate teaching laboratory to the research laboratory. The evolution of an intermediate organic synthesis laboratory course Journal of Chemical Education. 83: 1835-1843. DOI: 10.1021/Ed083P1835 |
0.733 |
|
| 2006 |
Bowman MD, Jacobson MM, Pujanauski BG, Blackwell HE. Efficient synthesis of small molecule macroarrays: optimization of the macroarray synthesis platform and examination of microwave and conventional heating methods Tetrahedron. 62: 4715-4727. DOI: 10.1016/J.Tet.2006.02.083 |
0.561 |
|
| 2005 |
Lin Q, O'Neill JC, Blackwell HE. Small molecule macroarray construction via Ugi four-component reactions Organic Letters. 7: 4455-4458. PMID 16178557 DOI: 10.1021/Ol051684O |
0.434 |
|
| 2005 |
Geske GD, Wezeman RJ, Siegel AP, Blackwell HE. Small molecule inhibitors of bacterial quorum sensing and biofilm formation. Journal of the American Chemical Society. 127: 12762-3. PMID 16159245 DOI: 10.1021/Ja0530321 |
0.817 |
|
| 2005 |
Blackwell HE. Bacterial crowd control with iron Chemistry and Biology. 12: 721-723. PMID 16039519 DOI: 10.1016/J.Chembiol.2005.07.001 |
0.328 |
|
| 2005 |
Gorske BC, Jewell SA, Guerard EJ, Blackwell HE. Expedient synthesis and design strategies for new peptoid construction Organic Letters. 7: 1521-1524. PMID 15816742 DOI: 10.1021/Ol0502984 |
0.781 |
|
| 2004 |
Bowman MD, Jeske RC, Blackwell HE. Microwave-accelerated SPOT-synthesis on cellulose supports. Organic Letters. 6: 2019-22. PMID 15176808 DOI: 10.1021/Ol049313F |
0.554 |
|
| 2003 |
Zhao Y, Dai X, Blackwell HE, Schreiber SL, Chory J. SIR1, an upstream component in auxin signaling identified by chemical genetics. Science (New York, N.Y.). 301: 1107-10. PMID 12893885 DOI: 10.1126/Science.1084161 |
0.486 |
|
| 2002 |
Spring DR, Krishnan S, Blackwell HE, Schreiber SL. Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform. Journal of the American Chemical Society. 124: 1354-63. PMID 11841305 DOI: 10.1021/Ja017248O |
0.717 |
|
| 2001 |
Blackwell HE, Pérez L, Stavenger RA, Tallarico JA, Cope Eatough E, Foley MA, Schreiber SL. A one-bead, one-stock solution approach to chemical genetics: part 1. Chemistry & Biology. 8: 1167-82. PMID 11755396 DOI: 10.1016/S1074-5521(01)00085-0 |
0.745 |
|
| 2001 |
Blackwell HE, Pérez L, Schreiber SL. Decoding Products of Diversity Pathways from Stock Solutions Derived from Single Polymeric Macrobeads H.E.B. and L.P. contributed equally to this work. We thank the National Institute of General Medical Sciences (GM-52067) for the support of this research. We are especially grateful to Dr. Andrew Tyler for expert mass spectroscopy support. The Harvard ICCB is supported by Merck & Co., Merck KGaA, the Keck Foundation, and the National Cancer Institute. H.E.B. is supported by a postdoctoral fellowship from the Jane Coffin Childs Memorial Fund for Medical Research (sponsored by Merck & Co.). L.P. is a Research Fellow, and S.L.S. is an Investigator with the Howard Hughes Medical Institute at the Department of Chemistry and Chemical Biology, Harvard University. Angewandte Chemie (International Ed. in English). 40: 3421-3425. PMID 11592158 DOI: 10.1002/1521-3773(20010917)40:18<3421::Aid-Anie3421>3.0.Co;2-B |
0.467 |
|
| 2001 |
Blackwell HE, Sadowsky JD, Howard RJ, Sampson JN, Chao JA, Steinmetz WE, O'Leary DJ, Grubbs RH. Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides. The Journal of Organic Chemistry. 66: 5291-302. PMID 11485448 DOI: 10.1021/Jo015533K |
0.461 |
|
| 2001 |
Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. The Journal of Biological Chemistry. 276: 38837-43. PMID 11483616 DOI: 10.1074/Jbc.M106779200 |
0.681 |
|
| 2001 |
Blackwell HE, Clemons PA, Schreiber SL. Exploiting site-site interactions on solid support to generate dimeric molecules. Organic Letters. 3: 1185-8. PMID 11348190 DOI: 10.1021/Ol015647I |
0.617 |
|
| 2001 |
Blackwell HE, Pérez L, Stavenger RA, Tallarico JA, Cope Eatough E, Foley MA, Schreiber SL. A one-bead, one-stock solution approach to chemical genetics: Part 1 Chemistry and Biology. 8: 1167-1182. DOI: 10.1016/S1074-5521(01)00085-0 |
0.663 |
|
| 2000 |
Blackwell HE, O'Leary DJ, Chatterjee AK, Washenfelder RA, Bussmann DA, Grubbs RH. New approaches to olefin cross-metathesis Journal of the American Chemical Society. 122: 58-71. DOI: 10.1021/Ja993063U |
0.593 |
|
| 1999 |
O'Leary DJ, Blackwell HE, Washenfelder RA, Miura K, Grubbs RH. Terminal olefin cross-metathesis with acrolein acetals Tetrahedron Letters. 40: 1091-1094. DOI: 10.1016/S0040-4039(98)02641-0 |
0.4 |
|
| 1998 |
Blackwell HE, Grubbs RH. Highly Efficient Synthesis of Covalently Cross-Linked Peptide Helices by Ring-Closing Metathesis. Angewandte Chemie (International Ed. in English). 37: 3281-3284. PMID 29711420 DOI: 10.1002/(Sici)1521-3773(19981217)37:23<3281::Aid-Anie3281>3.0.Co;2-V |
0.451 |
|
| 1998 |
O'Leary DJ, Blackwell HE, Washenfelder RA, Grubbs RH. A new method for cross-metathesis of terminal olefins Tetrahedron Letters. 39: 7427-7430. DOI: 10.1016/S0040-4039(98)01647-5 |
0.383 |
|
| 1998 |
Blackwell HE, Grubbs RH. Highly efficient synthesis of covalently cross-linked peptide helices by ring-closing metathesis Angewandte Chemie - International Edition. 37: 3281-3284. DOI: 10.1002/(SICI)1521-3773(19981217)37:23<3281::AID-ANIE3281>3.0.CO;2-V |
0.374 |
|
| 1998 |
Blackwell HE, Grubbs RH. Die Ringschluß-Olefin-Metathese als hocheffiziente Methode zur Synthese kovalent querverbrückter Peptide Angewandte Chemie. 110: 3469-3472. DOI: 10.1002/(Sici)1521-3757(19981204)110:23<3469::Aid-Ange3469>3.0.Co;2-A |
0.417 |
|
| 1996 |
Miller SJ, Blackwell HE, Grubbs RH. Application of ring-closing metathesis to the synthesis of rigidified amino acids and peptides Journal of the American Chemical Society. 118: 9606-9614. DOI: 10.1021/Ja961626L |
0.534 |
|
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