Giuseppe M. Attardi, M.D.
|Biology||California Institute of Technology, Pasadena, CA|
Area:Mitochondrial biogenesis, mitochondrial genetics
Discovered heterogeneous nuclear RNA in avian and mammalian cells. Discovered mtDNA transcription in mammalian cells. Showed complete symmetrical transcription of mtDNA. Made early transcript maps.
First mammalian mtDNA-less cells were created in his laboratory. Established cellular models of mitochondrial diseases.