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Amy M. Barrios

Affiliations: 
Chemistry: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Inorganic Chemistry, Pharmaceutical Chemistry, Biochemistry
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Parents

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Children

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Shamila S. Gunatilleke grad student 2007 USC
Sayantan Mitra grad student 2007 USC
Caitlin E. Hubbard grad student 2009 USC
Mark R. Karver grad student 2009 USC

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Publications

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Wang H, Gaston R, Ahmed KT, et al. (2023) Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1. Chemmedchem. e202300187
McCullough BS, Wang H, Barrios AM. (2022) Inhibitor Screen Identifies Covalent Inhibitors of the Protein Histidine Phosphatase PHPT1. Acs Medicinal Chemistry Letters. 13: 1198-1201
Barrios AM. (2020) PTPs: Degrading the Undruggable. Journal of Medicinal Chemistry
McCullough BS, Barrios AM. (2020) Fluorogenic probes for imaging cellular phosphatase activity. Current Opinion in Chemical Biology. 57: 34-40
McCullough BS, Barrios AM. (2020) In Vitro Assays for Measuring Protein Histidine Phosphatase Activity. Methods in Molecular Biology (Clifton, N.J.). 2077: 109-120
McCullough BS, Batsomboon P, Hutchinson KB, et al. (2019) Synthesis and PTP Inhibitory Activity of Illudalic Acid and Its Methyl Ether, with Insights into Selectivity for LAR PTP over Other Tyrosine Phosphatases under Physiologically Relevant Conditions. Journal of Natural Products
Ma ES, Barrios AM. (2019) Rational design of a SHP-2 targeted, fluorogenic peptide substrate. Bioorganic & Medicinal Chemistry Letters
McCullough BS, Barrios AM. (2018) Facile, Fluorogenic Assay for Protein Histidine Phosphatase Activity. Biochemistry
Biswas S, McCullough BS, Ma ES, et al. (2017) Dual colorimetric and fluorogenic probes for visualizing tyrosine phosphatase activity. Chemical Communications (Cambridge, England)
Thorson MK, Van Wagoner RM, Harper MK, et al. (2015) Marine natural products as inhibitors of cystathionine beta-synthase activity. Bioorganic & Medicinal Chemistry Letters. 25: 1064-6
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