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Cheryl Arrowsmith

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
General Biophysics, Biochemistry
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"Cheryl Arrowsmith"
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Parents

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Children

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Valerie K. Booth grad student 2000 University of Toronto
Timothy S. Davison grad student 2004 University of Toronto
Blair R. Szymczyna grad student 2004 University of Toronto
Jack C. Liao grad student 2011 University of Toronto
Nataliya Nady grad student 2012 University of Toronto

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Publications

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Münzker L, Kimani SW, Fowkes MM, et al. (2024) A ligand discovery toolbox for the WWE domain family of human E3 ligases. Communications Biology. 7: 901
Dilworth D, Hanley RP, Ferreira de Freitas R, et al. (2021) A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization. Nature Chemical Biology
Mann MK, Zepeda-Velázquez CA, González-Álvarez H, et al. (2021) Structure-Activity Relationship of USP5 Inhibitors. Journal of Medicinal Chemistry
Dölle A, Adhikari B, Krämer A, et al. (2021) Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Journal of Medicinal Chemistry
Ferreira de Freitas R, Liu Y, Szewczyk MM, et al. (2021) Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. Journal of Medicinal Chemistry
Tauber M, Kreuz S, Lemak A, et al. (2020) Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Research
Arrowsmith CH, Schapira M. (2019) Targeting non-bromodomain chromatin readers. Nature Structural & Molecular Biology. 26: 863-869
Mader P, Mendoza-Sanchez R, Iqbal A, et al. (2019) Identification and characterization of the first fragment hits for SETDB1 Tudor domain. Bioorganic & Medicinal Chemistry
Krug B, De Jay N, Harutyunyan AS, et al. (2019) Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 35: 782-797.e8
Ivanochko D, Halabelian L, Henderson E, et al. (2018) Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. Nucleic Acids Research
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