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Judith A. Kelly

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
General Biophysics
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"Judith Kelly"
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Nicholas R. Silvaggi grad student 2003 University of Connecticut

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Llinás A, Ahmed N, Cordaro M, et al. (2005) Inactivation of bacterial DD-peptidase by beta-sultams. Biochemistry. 44: 7738-46
Silvaggi NR, Josephine HR, Kuzin AP, et al. (2005) Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". Journal of Molecular Biology. 345: 521-33
Silvaggi NR, Kaur K, Adediran SA, et al. (2004) Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors. Biochemistry. 43: 7046-53
Silvaggi NR, Anderson JW, Brinsmade SR, et al. (2003) The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state. Biochemistry. 42: 1199-208
McDonough MA, Anderson JW, Silvaggi NR, et al. (2002) Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins. Journal of Molecular Biology. 322: 111-22
Kelly JA, Brinsmade SR, Silvaggi NR. (2002) Trapping reaction intermediates: a transition state on the R61 DD-peptidase catalytic pathway Acta Crystallographica Section a Foundations of Crystallography. 58: c103-c103
Lee W, McDonough MA, Kotra LP, et al. (2001) A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis Proceedings of the National Academy of Sciences of the United States of America. 98: 1427-1431
McDonough MA, Klei HE, Kelly JA. (1999) Crystal structure of penicillin G acylase from the Brol mutant strain of Providencia rettgeri Protein Science. 8: 1971-1981
Kelly JA, Kuzin AP, Charlier P, et al. (1998) X-ray studies of enzymes that interact with penicillins. Cellular and Molecular Life Sciences : Cmls. 54: 353-8
Klei HE, Daumy GO, Kelly JA. (1995) Purification and preliminary crystallographic studies of penicillin G acylase from Providencia rettgeri Protein Science. 4: 433-441
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