☰

Michael Cascio - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Biochemistry
Tree Info Similar researchers PubMed Report error

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tomcho KA, Gering HE, Pellegrino A, Lapinsky DJ, Cascio M. Using a Network of Single Site Specific Mutations and Crosslinking Mass Spectrometry (CXMS) to Refine the Structure and Dynamics of the Human Alpha 1 Glycine Receptor (GLYR) Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3154  0.414
2019 Tomcho KA, Gering HE, Veeramachaneni RJ, Lapinsky DJ, Cascio M. Targeted State Dependent Crosslinking Mass Spectrometry (CXMS) of the Human Alpha 1 Glycine Receptor (GLyR) Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2120  0.432
2019 Ferraro NA, Cascio M. Differential State-Dependent Crosslinking of Azi-Cholesterol with Human A1 Glycine Receptor using Mass Spectrometry Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1227  0.355
2018 Yarravarapu N, Geffert L, Surratt CK, Cascio M, Lapinsky DJ. Clickable photoaffinity ligands for the human serotonin transporter based on the selective serotonin reuptake inhibitor (S)-citalopram. Bioorganic & Medicinal Chemistry Letters. PMID 30266542 DOI: 10.1016/J.Bmcl.2018.09.029  0.306
2018 Ferraro NA, Cascio M. Crosslinking-mass spectrometry (CX-MS) studies of cholesterol interactions with human α1 glycine receptor. Analytical Chemistry. PMID 29356493 DOI: 10.1021/Acs.Analchem.7B03639  0.427
2017 Tomcho KA, Veeramachaneni RJ, Lapinsky DJ, Madura J, Cascio M. Crosslinking-Mass Spectrometry of Targeted Single Cys Mutants to Refine Allostery and Model Building in the Glycine Receptor Biophysical Journal. 112: 321a-322a. DOI: 10.1016/J.Bpj.2016.11.1742  0.476
2016 Divito EB, Kroniser KM, Cascio M. Multidimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry for Identification of Bioactive Fatty Acyl Derivatives. Frontiers in Physiology. 7: 608. PMID 28018237 DOI: 10.3389/Fphys.2016.00608  0.361
2016 Veeramachaneni RJ, Donelan C, Cascio M. Mass Spectrometry Coupled with Crosslinking as a Structural Tool for Structural Determination of Human α1 Glycine Receptor Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2432  0.464
2016 Ferraro N, Benner E, Madura J, Cascio M. Crosslinking/MS Studies of Cholesterol Interactions with Human α1 Glycine Receptor Biophysical Journal. 110: 355a. DOI: 10.1016/J.Bpj.2015.11.1918  0.388
2016 Cascio M, Veeramachaneni RJ, Madura J. Human α1 Glycine Receptor Allostery as Identified by State-Dependent Crosslinking Studies Biophysical Journal. 110: 201a. DOI: 10.1016/J.Bpj.2015.11.1124  0.489
2015 Cascio MG, Zamberletti E, Marini P, Parolaro D, Pertwee RG. The phytocannabinoid, Δ9-tetrahydrocannabivarin, can act through 5-HT1A receptors to produce antipsychotic effects British Journal of Pharmacology. 172: 1305-1318. DOI: 10.1111/bph.13000  0.325
2014 Liu Z, Szarecka A, Yonkunas M, Speranskiy K, Kurnikova M, Cascio M. Crosslinking constraints and computational models as complementary tools in modeling the extracellular domain of the glycine receptor. Plos One. 9: e102571. PMID 25025226 DOI: 10.1371/Journal.Pone.0102571  0.524
2014 Donelan CA, Veeramachaneni R, Davic A, Cascio M. Methods for Identification of State-Dependent Crosslinks for Structural Determination of Membrane Proteins Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3050  0.437
2014 Veeramachaneni RJ, Donelan C, Cascio M. Towards Structural and Functional Determination of a Non-Desensitizing α1 Glycine Receptor Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3049  0.44
2013 Marini P, Cascio MG, King A, Pertwee RG, Ross RA. Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors. British Journal of Pharmacology. 169: 887-99. PMID 23711022 DOI: 10.1111/Bph.12191  0.345
2012 Divito EB, Davic AP, Johnson ME, Cascio M. Electrospray ionization and collision induced dissociation mass spectrometry of primary fatty acid amides. Analytical Chemistry. 84: 2388-94. PMID 22283789 DOI: 10.1021/Ac203158U  0.323
2012 Bolognini D, Cascio MG, Parolaro D, Pertwee RG. AM630 behaves as a protean ligand at the human cannabinoid CB 2 receptor British Journal of Pharmacology. 165: 2561-2574. PMID 21615724 DOI: 10.1111/J.1476-5381.2011.01503.X  0.317
2012 Donelan CA, Veeramachaneni R, Lapinsky DJ, Cascio M. Using Crosslinking and Mass Spectrometry to Study Glycine Receptor Allostery Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3336  0.484
2011 Goss JR, Cascio M, Goins WF, Huang S, Krisky DM, Clarke RJ, Johnson JW, Yokoyama H, Yoshimura N, Gold MS, Glorioso JC. HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 500-6. PMID 21081904 DOI: 10.1038/Mt.2010.246  0.322
2011 Cascio MG, Pertwee R. The function of the endocannabinoid system Marijuana and Madness: Second Edition. 23-34. DOI: 10.1017/CBO9780511706080.004  0.366
2010 Ruthstein S, Stone KM, Cunningham TF, Ji M, Cascio M, Saxena S. Pulsed electron spin resonance resolves the coordination site of Cu²(+) ions in α1-glycine receptor. Biophysical Journal. 99: 2497-506. PMID 20959090 DOI: 10.1016/J.Bpj.2010.08.050  0.393
2010 Tseng CN, Zhang L, Wu SL, Wang WF, Wang ZZ, Cascio M. Asparagine of z8 insert is critical for the affinity, conformation, and acetylcholine receptor-clustering activity of neural agrin. The Journal of Biological Chemistry. 285: 27641-51. PMID 20566625 DOI: 10.1074/Jbc.M110.130625  0.325
2010 Cascio MG, Gauson LA, Stevenson LA, Ross RA, Pertwee RG. Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. British Journal of Pharmacology. 159: 129-41. PMID 20002104 DOI: 10.1111/J.1476-5381.2009.00515.X  0.362
2010 Cascio MG, Bolognini D, Pertwee RG, Palazzo E, Corelli F, Pasquini S, Di Marzo V, Maione S. In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonists Pharmacological Research. 61: 349-354. PMID 19961936 DOI: 10.1016/J.Phrs.2009.11.011  0.301
2009 Cascio M, Goss JR, Huang S, Krisky DM, Clarke RJ, Johnson JW, Glorioso JC. Targeted Delivery of Glycine Receptors to Peripheral Neurons as Treatment for Pain Biophysical Journal. 96: 487a. DOI: 10.1016/J.Bpj.2008.12.2511  0.33
2008 Liu Z, Ramanoudjame G, Liu D, Fox RO, Jayaraman V, Kurnikova M, Cascio M. Overexpression and functional characterization of the extracellular domain of the human alpha1 glycine receptor. Biochemistry. 47: 9803-10. PMID 18710260 DOI: 10.1021/Bi800659X  0.484
2008 Cheng MH, Coalson RD, Cascio M, Kurnikova M. Computational prediction of ion permeation characteristics in the glycine receptor modified by photo-sensitive compounds. Journal of Computer-Aided Molecular Design. 22: 563-70. PMID 18368498 DOI: 10.1007/S10822-008-9200-0  0.349
2008 Zhang B, Sun C, Jin S, Cascio M, Montelaro RC. Mapping of equine lentivirus receptor 1 residues critical for equine infectious anemia virus envelope binding. Journal of Virology. 82: 1204-13. PMID 18032504 DOI: 10.1128/Jvi.01393-07  0.433
2008 Cheng MH, Coalson RD, Cascio M. Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: implications for the channel potentiation mechanism. Proteins. 71: 972-81. PMID 18004757 DOI: 10.1002/Prot.21784  0.369
2007 Srinivasan R, Huang S, Chaudhry S, Sculptoreanu A, Krisky D, Cascio M, Friedman PA, de Groat WC, Wolfe D, Glorioso JC. An HSV vector system for selection of ligand-gated ion channel modulators. Nature Methods. 4: 733-9. PMID 17676048 DOI: 10.1038/Nmeth1077  0.393
2007 Brizzi A, Cascio MG, Brizzi V, Bisogno T, Dinatolo MT, Martinelli A, Tuccinardi T, Di Marzo V. Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors Bioorganic and Medicinal Chemistry. 15: 5406-5416. PMID 17561406 DOI: 10.1016/j.bmc.2007.05.060  0.302
2007 Cheng MH, Cascio M, Coalson RD. Homology modeling and molecular dynamics simulations of the alpha1 glycine receptor reveals different states of the channel. Proteins. 68: 581-93. PMID 17469203 DOI: 10.1002/Prot.21435  0.451
2007 Speranskiy K, Cascio M, Kurnikova M. Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domain. Proteins. 67: 950-60. PMID 17357155 DOI: 10.1002/Prot.21251  0.453
2007 Iyer AK, Tran KT, Borysenko CW, Cascio M, Camacho CJ, Blair HC, Bahar I, Wells A. Tenascin cytotactin epidermal growth factor-like repeat binds epidermal growth factor receptor with low affinity. Journal of Cellular Physiology. 211: 748-58. PMID 17311283 DOI: 10.1002/Jcp.20986  0.363
2006 Cascio M. Modulating inhibitory ligand-gated ion channels. The Aaps Journal. 8: E353-61. PMID 16796386 DOI: 10.1007/Bf02854906  0.467
2005 Brizzi A, Brizzi V, Cascio MG, Bisogno T, Sirianni R, Marzo VD. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors Journal of Medicinal Chemistry. 48: 7343-7350. PMID 16279794 DOI: 10.1021/jm0501533  0.311
2005 Cascio M. Connexins and their environment: effects of lipids composition on ion channels. Biochimica Et Biophysica Acta. 1711: 142-53. PMID 15955299 DOI: 10.1016/J.Bbamem.2004.12.001  0.369
2005 Cheng MH, Cascio M, Coalson RD. Theoretical studies of the M2 transmembrane segment of the glycine receptor: models of the open pore structure and current-voltage characteristics. Biophysical Journal. 89: 1669-80. PMID 15951389 DOI: 10.1529/Biophysj.105.060368  0.474
2004 Cascio M, Mayor JA, Kaplan RS. Analysis of the secondary structure of the cys-less yeast mitochondrial citrate transport protein and four single-cys variants by circular dichroism. Journal of Bioenergetics and Biomembranes. 36: 429-38. PMID 15534390 DOI: 10.1023/B:Jobb.0000047325.48943.71  0.34
2004 Cascio M. Structure and function of the glycine receptor and related nicotinicoid receptors. The Journal of Biological Chemistry. 279: 19383-6. PMID 15023997 DOI: 10.1074/Jbc.R300035200  0.435
2003 Tillman TS, Cascio M. Effects of membrane lipids on ion channel structure and function. Cell Biochemistry and Biophysics. 38: 161-90. PMID 12777713 DOI: 10.1385/Cbb:38:2:161  0.4
2003 Tseng CN, Zhang L, Cascio M, Wang ZZ. Calcium plays a critical role in determining the acetylcholine receptor-clustering activities of alternatively spliced isoforms of Agrin. The Journal of Biological Chemistry. 278: 17236-45. PMID 12621054 DOI: 10.1074/Jbc.M300282200  0.338
2002 Cascio M. Glycine receptors: lessons on topology and structural effects of the lipid bilayer. Biopolymers. 66: 359-68. PMID 12539264 DOI: 10.1002/Bip.10314  0.558
2002 Leite JF, Gribble B, Randolph N, Cascio M. In vitro interaction of the glycine receptor with the leptin receptor. Physiology & Behavior. 77: 565-9. PMID 12527000 DOI: 10.1016/S0031-9384(02)00912-5  0.723
2002 Leite JF, Cascio M. Probing the topology of the glycine receptor by chemical modification coupled to mass spectrometry. Biochemistry. 41: 6140-8. PMID 11994009 DOI: 10.1021/Bi015895M  0.73
2001 Leite JF, Cascio M. Structure of ligand-gated ion channels: critical assessment of biochemical data supports novel topology. Molecular and Cellular Neurosciences. 17: 777-92. PMID 11358478 DOI: 10.1006/Mcne.2001.0984  0.736
2001 Cascio M, Shenkel S, Grodzicki RL, Sigworth FJ, Fox RO. Functional reconstitution and characterization of recombinant human alpha 1-glycine receptors. The Journal of Biological Chemistry. 276: 20981-8. PMID 11145968 DOI: 10.1074/jbc.M010968200  0.448
2000 Leite JF, Amoscato AA, Cascio M. Coupled proteolytic and mass spectrometry studies indicate a novel topology for the glycine receptor. The Journal of Biological Chemistry. 275: 13683-9. PMID 10788487 DOI: 10.1074/Jbc.275.18.13683  0.728
1999 Chakraborty A, Dyer KF, Cascio M, Mietzner TA, Tweardy DJ. Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor. Blood. 93: 15-24. PMID 9864141 DOI: 10.1182/Blood.V93.1.15.401A46_15_24  0.337
1995 Cascio M, Kumar NM, Safarik R, Gilula NB. Physical characterization of gap junction membrane connexons (hemi-channels) isolated from rat liver Journal of Biological Chemistry. 270: 18643-18648. PMID 7629194 DOI: 10.1074/Jbc.270.31.18643  0.315
1995 Cascio M. [10] Baculovirus expression of receptors and channels Methods in Neurosciences. 25: 175-200. DOI: 10.1016/S1043-9471(05)80040-0  0.41
1993 Cascio M, Schoppa NE, Grodzicki RL, Sigworth FJ, Fox RO. Functional expression and purification of a homomeric human alpha 1 glycine receptor in baculovirus-infected insect cells. The Journal of Biological Chemistry. 268: 22135-42. PMID 8408073  0.337
1988 Cascio M, Wallace BA. Conformation of alamethicin in phospholipid vesicles: Implications for insertion models Proteins: Structure, Function and Genetics. 4: 89-98. PMID 3227017 DOI: 10.1002/Prot.340040203  0.362
1984 Cascio M, Wallace BA. The effects of environment on the conformation of the alamethicin membrane channel Annals of the New York Academy of Sciences. 527-529. DOI: 10.1111/J.1749-6632.1984.Tb13873.X  0.328
Show low-probability matches.