| Year |
Citation |
Score |
| 2021 |
Bentz J, Ellens H. Case Study 8: Status of the Structural Mass Action Kinetic Model of P-gp-Mediated Transport Through Confluent Cell Monolayers. Methods in Molecular Biology (Clifton, N.J.). 2342: 737-763. PMID 34272715 DOI: 10.1007/978-1-0716-1554-6_27 |
0.357 |
|
| 2018 |
Ellens H, Meng Z, Le Marchand SJ, Bentz J. Mechanistic kinetic modeling generates system-independent P-glycoprotein mediated transport elementary rate constants for inhibition and, in combination with 3D SIM microscopy, elucidates the importance of microvilli morphology on P-glycoprotein mediated efflux activity. Expert Opinion On Drug Metabolism & Toxicology. PMID 29788828 DOI: 10.1080/17425255.2018.1480720 |
0.454 |
|
| 2018 |
Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J. Derivation of a system-independent Ki for Pgp-mediated digoxin transport from system-dependent IC50 data by accounting for the contribution of additional digoxin transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29317410 DOI: 10.1124/Dmd.117.075606 |
0.405 |
|
| 2016 |
Meng Z, Ellens H, Bentz J. Extrapolation of elementary rate constants of P-glycoprotein mediated transport from MDCKII-hMDR1 to Caco-2 cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27856526 DOI: 10.1124/Dmd.116.072140 |
0.454 |
|
| 2016 |
Meng Z, Le Marchand S, Agnani D, Szapacs M, Ellens H, Bentz J. Microvilli morphology can affect efflux active P-glycoprotein in confluent MDCKII-NKI_hMDR1 and Caco-2 cell monolayers. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27856525 DOI: 10.1124/Dmd.116.072157 |
0.416 |
|
| 2015 |
O'Connor M, Lee C, Ellens H, Bentz J. A novel application of t-statistics to objectively assess the quality of IC50 fits for P-glycoprotein and other transporters. Pharmacology Research & Perspectives. 3: e00078. PMID 25692007 DOI: 10.1002/Prp2.78 |
0.355 |
|
| 2014 |
Bentz J, Ellens H. A structural model for the mass action kinetic analysis of P-gp mediated transport through confluent cell monolayers. Methods in Molecular Biology (Clifton, N.J.). 1113: 289-316. PMID 24523118 DOI: 10.1007/978-1-62703-758-7_14 |
0.478 |
|
| 2013 |
Lumen AA, Li L, Li J, Ahmed Z, Meng Z, Owen A, Ellens H, Hidalgo IJ, Bentz J. Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. Plos One. 8: e69394. PMID 23976943 DOI: 10.1371/Journal.Pone.0069394 |
0.734 |
|
| 2013 |
Zamek-Gliszczynski MJ, Lee CA, Poirier A, Bentz J, Chu X, Ellens H, Ishikawa T, Jamei M, Kalvass JC, Nagar S, Pang KS, Korzekwa K, Swaan PW, Taub ME, Zhao P, et al. ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-mediated PK and DDIs in humans. Clinical Pharmacology and Therapeutics. 94: 64-79. PMID 23588311 DOI: 10.1038/Clpt.2013.45 |
0.312 |
|
| 2013 |
Bentz J. The IC50 for Inhibition of Digoxin Transport Across Confluent Cell Monolayers of P-gp Expressing Cell Lines is Often a Function of Inhibitor Binding to Both P-gp and an Unidentified Basolateral Digoxin Uptake Transporter Biophysical Journal. 104: 110a-111a. DOI: 10.1016/J.Bpj.2012.11.642 |
0.435 |
|
| 2011 |
Agnani D, Acharya P, Martinez E, Tran TT, Abraham F, Tobin F, Ellens H, Bentz J. Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm. Plos One. 6: e25086. PMID 22028772 DOI: 10.1371/Journal.Pone.0025086 |
0.665 |
|
| 2010 |
Lumen AA, Acharya P, Polli JW, Ayrton A, Ellens H, Bentz J. If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 260-9. PMID 19889884 DOI: 10.1124/Dmd.109.029843 |
0.745 |
|
| 2008 |
Acharya P, O'Connor MP, Polli JW, Ayrton A, Ellens H, Bentz J. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 452-60. PMID 17967933 DOI: 10.1124/Dmd.107.017301 |
0.651 |
|
| 2006 |
Acharya P, Tran TT, Polli JW, Ayrton A, Ellens H, Bentz J. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites. Biochemistry. 45: 15505-19. PMID 17176072 DOI: 10.1021/Bi060593B |
0.655 |
|
| 2005 |
Bentz J, Tran TT, Polli JW, Ayrton A, Ellens H. The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km. Pharmaceutical Research. 22: 1667-77. PMID 16180124 DOI: 10.1007/S11095-005-6627-Z |
0.424 |
|
| 2005 |
Tran TT, Mittal A, Aldinger T, Polli JW, Ayrton A, Ellens H, Bentz J. The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells. Biophysical Journal. 88: 715-38. PMID 15501934 DOI: 10.1529/Biophysj.104.045633 |
0.619 |
|
| 2004 |
Tran TT, Mittal A, Gales T, Maleeff B, Aldinger T, Polli JW, Ayrton A, Ellens H, Bentz J. Exact kinetic analysis of passive transport across a polarized confluent MDCK cell monolayer modeled as a single barrier. Journal of Pharmaceutical Sciences. 93: 2108-23. PMID 15236458 DOI: 10.1002/Jps.20105 |
0.574 |
|
| 2003 |
Mittal A, Leikina E, Chernomordik LV, Bentz J. Kinetically differentiating influenza hemagglutinin fusion and hemifusion machines. Biophysical Journal. 85: 1713-24. PMID 12944286 DOI: 10.1016/S0006-3495(03)74601-3 |
0.578 |
|
| 2003 |
Bentz J, Mittal A. Architecture of the influenza hemagglutinin membrane fusion site. Biochimica Et Biophysica Acta. 1614: 24-35. PMID 12873763 DOI: 10.1016/S0005-2736(03)00160-3 |
0.602 |
|
| 2002 |
Mittal A, Shangguan T, Bentz J. Measuring pKa of activation and pKi of inactivation for influenza hemagglutinin from kinetics of membrane fusion of virions and of HA expressing cells. Biophysical Journal. 83: 2652-66. PMID 12414698 DOI: 10.1016/S0006-3495(02)75275-2 |
0.591 |
|
| 2002 |
Tieleman DP, Bentz J. Molecular dynamics simulation of the evolution of hydrophobic defects in one monolayer of a phosphatidylcholine bilayer: relevance for membrane fusion mechanisms. Biophysical Journal. 83: 1501-10. PMID 12202375 DOI: 10.1016/S0006-3495(02)73920-9 |
0.351 |
|
| 2002 |
Mittal A, Leikina E, Bentz J, Chernomordik LV. Kinetics of influenza hemagglutinin-mediated membrane fusion as a function of technique. Analytical Biochemistry. 303: 145-52. PMID 11950214 DOI: 10.1006/Abio.2002.5590 |
0.586 |
|
| 2001 |
Mittal A, Bentz J. Comprehensive kinetic analysis of influenza hemagglutinin-mediated membrane fusion: role of sialate binding. Biophysical Journal. 81: 1521-35. PMID 11509365 DOI: 10.1016/S0006-3495(01)75806-7 |
0.621 |
|
| 2000 |
Bentz J, Mittal A. Deployment of membrane fusion protein domains during fusion. Cell Biology International. 24: 819-38. PMID 11067767 DOI: 10.1006/Cbir.2000.0632 |
0.604 |
|
| 2000 |
Bentz J. Membrane fusion mediated by coiled coils: A hypothesis Biophysical Journal. 78: 886-900. PMID 10653801 DOI: 10.1016/S0006-3495(00)76646-X |
0.436 |
|
| 2000 |
Bentz J. Minimal aggregate size and minimal fusion unit for the first fusion pore of influenza hemagglutinin-mediated membrane fusion Biophysical Journal. 78: 227-245. PMID 10620288 DOI: 10.1016/S0006-3495(00)76587-8 |
0.441 |
|
| 1998 |
Shangguan T, Siegel DP, Lear JD, Axelsen PH, Alford D, Bentz J. Morphological Changes and Fusogenic Activity of Influenza Virus Hemagglutinin Biophysical Journal. 74: 54-62. PMID 9449309 DOI: 10.1016/S0006-3495(98)77766-5 |
0.335 |
|
| 1996 |
Shangguan T, Alford D, Bentz J. Influenza virus - Liposome lipid mixing is leaky and largely insensitive to the material properties of the target membrane Biochemistry. 35: 4956-4965. PMID 8664288 DOI: 10.1021/Bi9526903 |
0.434 |
|
| 1994 |
Alford D, Ellens H, Bentz J. Fusion of influenza virus with sialic acid-bearing target membranes. Biochemistry. 33: 1977-1987. PMID 8117654 DOI: 10.1021/Bi00174A002 |
0.434 |
|
| 1992 |
Bentz J. Intermediates and kinetics of membrane fusion Biophysical Journal. 63: 448-459. PMID 1420890 DOI: 10.1016/S0006-3495(92)81622-3 |
0.442 |
|
| 1990 |
Ellens H, Bentz J, Mason D, Zhang F, White JM. Fusion of influenza hemagglutinin-expressing fibroblasts with glycophorin-bearing liposomes: Role of hemagglutinin surface density Biochemistry. 29: 9697-9707. PMID 2271610 DOI: 10.1021/Bi00493A027 |
0.409 |
|
| 1990 |
Bentz J, Ellens H, Alford D. An architecture for the fusion site of Influenza hemagglutinin Febs Letters. 276: 1-5. PMID 2265687 DOI: 10.1016/0014-5793(90)80492-2 |
0.344 |
|
| 1989 |
Siegel DP, Banschbach J, Alford D, Ellens H, Lis LJ, Quinn PJ, Yeagle PL, Bentz J. Physiological levels of diacylglycerols in phospholipid membranes induce membrane fusion and stabilize inverted phases. Biochemistry. 28: 3703-9. PMID 2751991 DOI: 10.1021/Bi00435A012 |
0.377 |
|
| 1989 |
Ellens H, Siegel DP, Alford D, Yeagle PL, Boni L, Lis LJ, Quinn PJ, Bentz J. Membrane fusion and inverted phases. Biochemistry. 28: 3692-703. PMID 2751990 DOI: 10.1021/Bi00435A011 |
0.321 |
|
| 1988 |
Bentz J, Alford D, Cohen J, Duzgunes N. La3+-induced fusion of phosphatidylserine liposomes. Close approach, intermembrane intermediates, and the electrostatic surface potential Biophysical Journal. 53: 593-607. PMID 3382713 DOI: 10.1016/S0006-3495(88)83138-2 |
0.428 |
|
| 1988 |
Bentz J, Nir S, Covell DG. Mass action kinetics of virus-cell aggregation and fusion Biophysical Journal. 54: 449-462. PMID 3207833 DOI: 10.1016/S0006-3495(88)82978-3 |
0.597 |
|
| 1988 |
Shavnin SA, Lima MCPd, Fedor J, Wood P, Bentz J, Düzgüneş N. Cholesterol affects divalent cation-induced fusion and isothermal phase transitions of phospholipid membranes Biochimica Et Biophysica Acta. 946: 405-416. PMID 3207754 DOI: 10.1016/0005-2736(88)90416-6 |
0.376 |
|
| 1988 |
Meers P, Bentz J, Alford D, Nir S, Papahadjopoulos D, Hong K. Synexin enhances the aggregation rate but not the fusion rate of liposomes. Biochemistry. 27: 4430-9. PMID 2971392 DOI: 10.1021/Bi00412A033 |
0.617 |
|
| 1987 |
Bentz J, Ellens H, Szoka FC. Destabilization of phosphatidylethanolamine-containing liposomes: Hexagonal phase and asymmetric membranes Biochemistry. 26: 2105-2116. PMID 3620441 DOI: 10.1021/Bi00382A008 |
0.379 |
|
| 1987 |
Bentz J, Ellens H. Membrane fusion: Kinetics and mechanisms Colloids and Surfaces. 30: 65-112. DOI: 10.1016/0166-6622(87)80204-4 |
0.428 |
|
| 1986 |
Ellens H, Bentz J, Szoka FC. Destabilization of phosphatidylethanolamine liposomes at the hexagonal phase transition temperature Biochemistry. 25: 285-294. PMID 3954998 DOI: 10.1021/Bi00350A001 |
0.337 |
|
| 1986 |
Ellens H, Bentz J, Szoka FC. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the Lα-HII phase transition Biochemistry. 25: 4141-4147. PMID 3741846 DOI: 10.1021/Bi00362A023 |
0.371 |
|
| 1986 |
Meers P, Hong K, Bentz J, Papahadjopoulos D. Spermine as a modulator of membrane fusion: interactions with acidic phospholipids. Biochemistry. 25: 3109-18. PMID 3730351 DOI: 10.1021/Bi00359A007 |
0.419 |
|
| 1985 |
Ellens H, Bentz J, Szoka FC. H+- and Ca2+-induced fusion and destabilization of liposomes Biochemistry. 24: 3099-3106. PMID 4027232 DOI: 10.1021/Bi00334A005 |
0.354 |
|
| 1985 |
Bentz J, Düzgüneş N, Nir S. Temperature dependence of divalent cation induced fusion of phosphatidylserine liposomes: Evaluation of the kinetic rate constants Biochemistry. 24: 1064-1072. PMID 3994991 DOI: 10.1021/BI00325A039 |
0.546 |
|
| 1985 |
Bentz J, Ellens H, Lai MZ, Szoka FC. On the correlation between HII phase and the contact-induced destabilization of phosphatidylethanolamine-containing membranes Proceedings of the National Academy of Sciences of the United States of America. 82: 5742-5745. PMID 3862092 DOI: 10.1073/Pnas.82.17.5742 |
0.366 |
|
| 1984 |
Ellens H, Bentz J, Szoka FC. PH-Induced destabilization of phosphatidylethanolamine-containing liposomes: Role of bilayer contact Biochemistry. 23: 1532-1538. PMID 6722105 DOI: 10.1021/Bi00302A029 |
0.341 |
|
| 1984 |
Heath TD, Fraley RT, Bentz J, Voss EW, Herron JN, Papahadjopoulos D. Antibody-directed liposomes. Determination of affinity constants for soluble and liposome-bound antifluorescein. Biochimica Et Biophysica Acta. 770: 148-58. PMID 6421325 DOI: 10.1016/0005-2736(84)90124-X |
0.31 |
|
| 1983 |
Nir S, Düzgüneş N, Bentz J. Binding of monovalent cations to phosphatidylserine and modulation of Ca2+- and Mg2+-induced vesicle fusion Bba - Biomembranes. 735: 160-172. PMID 6626545 DOI: 10.1016/0005-2736(83)90271-7 |
0.627 |
|
| 1983 |
Bentz J, Düzgüneş N, Nir S. Kinetics of divalent cation induced fusion of phosphatidylserine vesicles: Correlation between fusogenic capacities and binding affinities Biochemistry. 22: 3320-3330. DOI: 10.1021/Bi00283A004 |
0.63 |
|
| 1983 |
Bentz J, Nir S, Wilschut J. Mass action kinetics of vesicle aggregation and fusion Colloids and Surfaces. 6: 333-363. DOI: 10.1016/0166-6622(83)80026-2 |
0.645 |
|
| 1983 |
Nir S, Bentz J, Wilschut J, Duzgunes N. Aggregation and fusion of phospholipid vesicles Progress in Surface Science. 13: 1-124. DOI: 10.1016/0079-6816(83)90010-2 |
0.641 |
|
| 1982 |
Nir S, Wilschut J, Bentz J. The rate of fusion of phospholipid vesicles and the role of bilayer curvature Bba - Biomembranes. 688: 275-278. PMID 7093279 DOI: 10.1016/0005-2736(82)90604-6 |
0.631 |
|
| 1981 |
Düzgüne N, Nir S, Wilschut J, Bentz J, Newton C, Portis A, Papahadjopoulos D. Calcium- and magnesium-induced fusion of mixed phosphatidylserine/phosphatidylcholine vesicles: effect of ion binding. The Journal of Membrane Biology. 59: 115-125. PMID 7241577 DOI: 10.1007/Bf01875709 |
0.602 |
|
| 1981 |
Bentz J, Nir S. Aggregation of colloidal particles modeled as a dynamical process Proceedings of the National Academy of Sciences of the United States of America. 78: 1634-1637. PMID 6940176 DOI: 10.1073/Pnas.78.3.1634 |
0.579 |
|
| 1981 |
Bentz J, Nir S. Mass action kinetics and equilibria of reversible aggregation Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases. 77: 1249-1275. DOI: 10.1039/F19817701249 |
0.572 |
|
| 1981 |
Nir S, Bentz J, Düzgüneş N. Two modes of reversible vesicle aggregation: particle size and the DLVO theory Journal of Colloid and Interface Science. 84: 266-269. DOI: 10.1016/0021-9797(81)90284-8 |
0.512 |
|
| 1980 |
Nir S, Bentz J, Wilschut J. Mass action kinetics of phosphatidylserine vesicle fusion as monitored by coalescence of internal vesicle volumes Biochemistry. 19: 6030-6036. PMID 7470447 DOI: 10.1021/Bi00567A013 |
0.607 |
|
| 1980 |
Bentz J, Nir S. Cation binding to membranes: Competition between mono-, di- and trivalent cations Bulletin of Mathematical Biology. 42: 191-220. PMID 7370443 DOI: 10.1007/BF02464638 |
0.478 |
|
| 1980 |
Bentz J, Nir S. Cation binding to membranes; competition between mono-, di-and trivalent cations Bulletin of Mathematical Biology. 42: 749. DOI: 10.1016/S0092-8240(80)80040-1 |
0.525 |
|
| 1980 |
Nir S, Bentz J. On the applicability of DLVO theory to cation-induced aggregation of phosphatidylserine vesicles Journal of Colloid and Interface Science. 74: 295-296. DOI: 10.1016/0021-9797(80)90193-9 |
0.535 |
|
| 1978 |
Nir S, Bentz J. On the forces between phospholipid bilayers Journal of Colloid and Interface Science. 65: 399-414. DOI: 10.1016/0021-9797(78)90091-7 |
0.55 |
|
| Show low-probability matches. |
