James L. Keck - Publications

Affiliations: 
Biomolecular Chemistry University of Wisconsin, Madison, Madison, WI 
Area:
structure, DNA replication

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bonde NJ, Kozlov AG, Cox MM, Lohman TM, Keck JL. Molecular insights into the prototypical single-stranded DNA-binding protein from . Critical Reviews in Biochemistry and Molecular Biology. 1-29. PMID 38770626 DOI: 10.1080/10409238.2024.2330372  0.527
2024 McMillan SD, Keck JL. Biochemical characterization of E. coli DnaC variants that alter DnaB helicase loading onto DNA. The Journal of Biological Chemistry. 107275. PMID 38588814 DOI: 10.1016/j.jbc.2024.107275  0.515
2024 Sandler SJ, Bonde NJ, Wood EA, Cox MM, Keck JL. The intrinsically disordered linker in the single-stranded DNA-binding protein influences DNA replication restart and recombination pathways in K-12. Journal of Bacteriology. e0033023. PMID 38470036 DOI: 10.1128/jb.00330-23  0.54
2023 Bonde NJ, Wood EA, Myers KS, Place M, Keck JL, Cox MM. Identification of genetic interactions in by transposon sequencing. Journal of Bacteriology. e0018423. PMID 38019006 DOI: 10.1128/jb.00184-23  0.398
2023 Ducos P, Duckworth A, Satyshur K, Keck J, Grant T. A 3.2 Å Resolution Structure of the PriA/PriB/Replication Fork Complex Reveals Mechanistic Insight into Bacterial DNA Replication Restart. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 29: 890-891. PMID 37613480 DOI: 10.1093/micmic/ozad067.439  0.475
2023 Cueny RR, Varma S, Schmidt KH, Keck JL. Biochemical properties of naturally occurring human bloom helicase variants. Plos One. 18: e0281524. PMID 37267408 DOI: 10.1371/journal.pone.0281524  0.527
2023 Cherry ME, Dubiel K, Henry C, Wood EA, Revitt-Mills SA, Keck JL, Cox MM, van Oijen AM, Ghodke H, Robinson A. Spatiotemporal Dynamics of Single-stranded DNA Intermediates in . Biorxiv : the Preprint Server For Biology. PMID 37214928 DOI: 10.1101/2023.05.08.539320  0.433
2023 Duckworth AT, Ducos PL, McMillan SD, Satyshur KA, Blumenthal KH, Deorio HR, Larson JA, Sandler SJ, Grant T, Keck JL. Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli. Nature Communications. 14: 2725. PMID 37169801 DOI: 10.1038/s41467-023-38144-x  0.506
2023 Osorio Garcia MA, Wood EA, Keck JL, Cox MM. Interaction with single-stranded DNA-binding protein (SSB) modulates Escherichia coli RadD DNA repair activities. The Journal of Biological Chemistry. 104773. PMID 37142225 DOI: 10.1016/j.jbc.2023.104773  0.601
2023 Bonde NJ, Henry C, Wood EA, Cox MM, Keck JL. Interaction with the carboxy-terminal tip of SSB is critical for RecG function in E. coli. Nucleic Acids Research. PMID 36912097 DOI: 10.1093/nar/gkad162  0.575
2023 Cueny RR, Varma S, Schmidt KH, Keck JL. Biochemical Properties of Naturally Occurring Human Bloom Helicase Variants. Biorxiv : the Preprint Server For Biology. PMID 36747637 DOI: 10.1101/2023.01.26.525669  0.526
2022 McKenzie AM, Henry C, Myers KS, Place MM, Keck JL. Identification of genetic interactions with priB links the PriA/PriB DNA replication restart pathway to double-strand DNA break repair in Escherichia coli. G3 (Bethesda, Md.). PMID 36326440 DOI: 10.1093/g3journal/jkac295  0.489
2022 Duckworth AT, Keck JL. Use of an unnatural amino acid to map helicase/DNA interfaces via photoactivated crosslinking. Methods in Enzymology. 672: 55-74. PMID 35934485 DOI: 10.1016/bs.mie.2022.02.019  0.459
2022 Osorio Garcia MA, Satyshur KA, Cox MM, Keck JL. X-ray crystal structure of the Escherichia coli RadD DNA repair protein bound to ADP reveals a novel zinc ribbon domain. Plos One. 17: e0266031. PMID 35482735 DOI: 10.1371/journal.pone.0266031  0.417
2022 Bilotti K, Potapov V, Pryor JM, Duckworth AT, Keck JL, Lohman GJS. Mismatch discrimination and sequence bias during end-joining by DNA ligases. Nucleic Acids Research. 50: 4647-4658. PMID 35438779 DOI: 10.1093/nar/gkac241  0.444
2022 Foster HR, Lin X, Srikant S, Cueny RR, Falbel TG, Keck JL, Gaudet R, Burton BM. Natural transformation protein ComFA exhibits single-stranded DNA translocase activity. Journal of Bacteriology. JB0051821. PMID 35041498 DOI: 10.1128/JB.00518-21  0.484
2021 Sandler SJ, Leroux M, Windgassen TA, Keck JL. Escherichia coli K-12 has two distinguishable PriA-PriB Replication Restart pathways. Molecular Microbiology. PMID 34423481 DOI: 10.1111/mmi.14802  0.457
2021 Duckworth AT, Windgassen TA, Keck JL. Examination of the roles of a conserved motif in the PriA helicase in structure-specific DNA unwinding and processivity. Plos One. 16: e0255409. PMID 34329356 DOI: 10.1371/journal.pone.0255409  0.56
2021 Puri N, Fernandez AJ, O'Shea Murray VL, McMillan S, Keck JL, Berger JM. The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader. Elife. 10. PMID 34036936 DOI: 10.7554/eLife.64232  0.711
2020 Paul T, Voter AF, Cueny RR, Gavrilov M, Ha T, Keck JL, Myong S. E. coli Rep helicase and RecA recombinase unwind G4 DNA and are important for resistance to G4-stabilizing ligands. Nucleic Acids Research. PMID 32449930 DOI: 10.1093/Nar/Gkaa442  0.326
2020 Anderson BW, Hao A, Satyshur KA, Keck JL, Wang JD. Molecular mechanism of regulation of the purine salvage enzyme XPRT by the alarmones pppGpp, ppGpp, and pGpp. Journal of Molecular Biology. PMID 32446804 DOI: 10.1016/J.Jmb.2020.05.013  0.44
2020 Wolak C, Ma HJ, Soubry N, Sandler SJ, Reyes-Lamothe R, Keck JL. Interaction with single-stranded DNA-binding protein localizes ribonuclease HI to DNA replication forks and facilitates R-loop removal. Molecular Microbiology. PMID 32426857 DOI: 10.1111/Mmi.14529  0.86
2020 Dubiel K, Henry C, Spenkelink LM, Kozlov AG, Wood EA, Jergic S, Dixon NE, van Oijen AM, Cox MM, Lohman TM, Sandler SJ, Keck JL. Development of a single-stranded DNA-binding protein fluorescent fusion toolbox. Nucleic Acids Research. PMID 32374866 DOI: 10.1093/Nar/Gkaa320  0.633
2019 Voter AF, Callaghan MM, Tippana R, Myong S, Dillard JP, Keck JL. Antigenic variation in occurs independently of RecQ-mediated unwinding of the G-quadruplex. Journal of Bacteriology. PMID 31740492 DOI: 10.1128/Jb.00607-19  0.407
2019 Anderson BW, Liu K, Wolak C, Dubiel K, She F, Satyshur KA, Keck JL, Wang JD. Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife. 8. PMID 31552824 DOI: 10.7554/Elife.47534  0.795
2019 Anderson BW, Liu K, Wolak C, Dubiel K, She F, Satyshur KA, Keck JL, Wang JD. Author response: Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction Elife. DOI: 10.7554/Elife.47534.056  0.765
2018 Windgassen TA, Leroux M, Sandler SJ, Keck JL. Function of a strand-separation pin element in the PriA DNA replication restart helicase. The Journal of Biological Chemistry. PMID 30593500 DOI: 10.1074/Jbc.Ra118.006870  0.648
2018 Dubiel K, Myers AR, Kozlov AG, Yang O, Zhang J, Ha T, Lohman TM, Keck JL. Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. Journal of Molecular Biology. PMID 30472092 DOI: 10.1016/J.Jmb.2018.11.019  0.583
2018 Voter AF, Qiu Y, Tippana R, Myong S, Keck JL. A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases. Nature Communications. 9: 4201. PMID 30305632 DOI: 10.1038/S41467-018-06751-8  0.395
2018 Windgassen TA, Leroux M, Satyshur KA, Sandler SJ, Keck JL. Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201718 DOI: 10.1073/Pnas.1809842115  0.661
2018 Bagchi D, Manosas M, Zhang W, Manthei KA, Hodeib S, Ducos B, Keck JL, Croquette V. Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB. Nucleic Acids Research. PMID 30053104 DOI: 10.1093/Nar/Gky647  0.836
2018 Bagchi D, Manosas M, Zhang W, Manthei KA, Hodeib S, Ducos B, Keck JL, Croquette V. Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB. Nucleic Acids Research. PMID 30053104 DOI: 10.1093/nar/gky647  0.456
2017 Windgassen TA, Wessel SR, Bhattacharyya B, Keck JL. Mechanisms of bacterial DNA replication restart. Nucleic Acids Research. PMID 29202195 DOI: 10.1093/Nar/Gkx1203  0.861
2017 Voter AF, Killoran MP, Ananiev GE, Wildman SA, Hoffmann FM, Keck JL. A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility. Slas Discovery. 2472555217712001. PMID 28570838 DOI: 10.1177/2472555217712001  0.828
2016 Windgassen TA, Keck JL. An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase. Nucleic Acids Research. PMID 27484483 DOI: 10.1093/Nar/Gkw690  0.62
2016 Leite WC, Galvão CW, Saab SC, Iulek J, Etto RM, Steffens MB, Chitteni-Pattu S, Stanage T, Keck JL, Cox MM. Structural and Functional Studies of H. seropedicae RecA Protein - Insights into the Polymerization of RecA Protein as Nucleoprotein Filament. Plos One. 11: e0159871. PMID 27447485 DOI: 10.1371/Journal.Pone.0159871  0.567
2016 Wessel SR, Cornilescu CC, Cornilescu G, Metz A, Leroux M, Hu K, Sandler SJ, Markley JL, Keck JL. Structure and Function of the PriC DNA Replication Restart Protein. The Journal of Biological Chemistry. PMID 27382050 DOI: 10.1074/Jbc.M116.738781  0.883
2016 Voter AF, Manthei KA, Keck JL. A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. Journal of Biomolecular Screening. PMID 26962873 DOI: 10.1177/1087057116635503  0.812
2015 Petzold C, Marceau AH, Miller KH, Marqusee S, Keck JL. Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity. The Journal of Biological Chemistry. 290: 14626-36. PMID 25903123 DOI: 10.1074/Jbc.M115.655134  0.859
2015 Manthei KA, Hill MC, Burke JE, Butcher SE, Keck JL. Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases. Proceedings of the National Academy of Sciences of the United States of America. 112: 4292-7. PMID 25831501 DOI: 10.1073/Pnas.1416746112  0.871
2015 Liu K, Myers AR, Pisithkul T, Claas KR, Satyshur KA, Amador-Noguez D, Keck JL, Wang JD. Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp. Molecular Cell. 57: 735-49. PMID 25661490 DOI: 10.1016/J.Molcel.2014.12.037  0.336
2014 Bhattacharyya B, Keck JL. Grip it and rip it: structural mechanisms of DNA helicase substrate binding and unwinding. Protein Science : a Publication of the Protein Society. 23: 1498-507. PMID 25131811 DOI: 10.1002/Pro.2533  0.749
2014 Walsh BW, Bolz SA, Wessel SR, Schroeder JW, Keck JL, Simmons LA. RecD2 helicase limits replication fork stress in Bacillus subtilis. Journal of Bacteriology. 196: 1359-68. PMID 24443534 DOI: 10.1128/Jb.01475-13  0.863
2014 Bhattacharyya B, George NP, Thurmes TM, Zhou R, Jani N, Wessel SR, Sandler SJ, Ha T, Keck JL. Structural mechanisms of PriA-mediated DNA replication restart. Proceedings of the National Academy of Sciences of the United States of America. 111: 1373-8. PMID 24379377 DOI: 10.1073/Pnas.1318001111  0.876
2013 Wessel SR, Marceau AH, Massoni SC, Zhou R, Ha T, Sandler SJ, Keck JL. PriC-mediated DNA replication restart requires PriC complex formation with the single-stranded DNA-binding protein. The Journal of Biological Chemistry. 288: 17569-78. PMID 23629733 DOI: 10.1074/Jbc.M113.478156  0.871
2013 Manthei KA, Keck JL. The BLM dissolvasome in DNA replication and repair. Cellular and Molecular Life Sciences : Cmls. 70: 4067-84. PMID 23543275 DOI: 10.1007/S00018-013-1325-1  0.838
2013 Marceau AH, Bernstein DA, Walsh BW, Shapiro W, Simmons LA, Keck JL. Protein interactions in genome maintenance as novel antibacterial targets. Plos One. 8: e58765. PMID 23536821 DOI: 10.1371/Journal.Pone.0058765  0.832
2013 Cahoon LA, Manthei KA, Rotman E, Keck JL, Seifert HS. Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin antigenic variation. Journal of Bacteriology. 195: 2255-61. PMID 23475972 DOI: 10.1128/Jb.02217-12  0.804
2013 Norais C, Servant P, Bouthier-de-la-Tour C, Coureux PD, Ithurbide S, Vannier F, Guerin PP, Dulberger CL, Satyshur KA, Keck JL, Armengaud J, Cox MM, Sommer S. The Deinococcus radiodurans DR1245 protein, a DdrB partner homologous to YbjN proteins and reminiscent of type III secretion system chaperones. Plos One. 8: e56558. PMID 23441204 DOI: 10.1371/Journal.Pone.0056558  0.345
2012 Rymer RU, Solorio FA, Tehranchi AK, Chu C, Corn JE, Keck JL, Wang JD, Berger JM. Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases. Structure (London, England : 1993). 20: 1478-89. PMID 22795082 DOI: 10.1016/J.Str.2012.05.017  0.805
2012 George NP, Ngo KV, Chitteni-Pattu S, Norais CA, Battista JR, Cox MM, Keck JL. Structure and cellular dynamics of Deinococcus radiodurans single-stranded DNA (ssDNA)-binding protein (SSB)-DNA complexes. The Journal of Biological Chemistry. 287: 22123-32. PMID 22570477 DOI: 10.1074/Jbc.M112.367573  0.826
2012 Hoadley KA, Xue Y, Ling C, Takata M, Wang W, Keck JL. Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome. Proceedings of the National Academy of Sciences of the United States of America. 109: 4437-42. PMID 22392978 DOI: 10.1073/Pnas.1117279109  0.553
2012 Yadav T, Carrasco B, Myers AR, George NP, Keck JL, Alonso JC. Genetic recombination in Bacillus subtilis: a division of labor between two single-strand DNA-binding proteins. Nucleic Acids Research. 40: 5546-59. PMID 22373918 DOI: 10.1093/Nar/Gks173  0.822
2012 Smith BC, Anderson MA, Hoadley KA, Keck JL, Cleland WW, Denu JM. Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry. 51: 243-56. PMID 22229411 DOI: 10.1021/Bi2015508  0.328
2011 Marceau AH, Bahng S, Massoni SC, George NP, Sandler SJ, Marians KJ, Keck JL. Structure of the SSB-DNA polymerase III interface and its role in DNA replication. The Embo Journal. 30: 4236-47. PMID 21857649 DOI: 10.1038/Emboj.2011.305  0.872
2011 Lindner SE, Llinás M, Keck JL, Kappe SH. The primase domain of PfPrex is a proteolytically matured, essential enzyme of the apicoplast. Molecular and Biochemical Parasitology. 180: 69-75. PMID 21856338 DOI: 10.1016/J.Molbiopara.2011.08.002  0.858
2011 Lu D, Myers AR, George NP, Keck JL. Mechanism of Exonuclease I stimulation by the single-stranded DNA-binding protein. Nucleic Acids Research. 39: 6536-45. PMID 21572106 DOI: 10.1093/Nar/Gkr315  0.836
2011 Page AN, George NP, Marceau AH, Cox MM, Keck JL. Structure and biochemical activities of Escherichia coli MgsA. The Journal of Biological Chemistry. 286: 12075-85. PMID 21297161 DOI: 10.1074/Jbc.M110.210187  0.869
2011 Gruenig MC, Lu D, Won SJ, Dulberger CL, Manlick AJ, Keck JL, Cox MM. Creating directed double-strand breaks with the Ref protein: a novel RecA-dependent nuclease from bacteriophage P1. The Journal of Biological Chemistry. 286: 8240-51. PMID 21193392 DOI: 10.1074/Jbc.M110.205088  0.719
2010 Kolonko EM, Albaugh BN, Lindner SE, Chen Y, Satyshur KA, Arnold KM, Kaufman PD, Keck JL, Denu JM. Catalytic activation of histone acetyltransferase Rtt109 by a histone chaperone. Proceedings of the National Academy of Sciences of the United States of America. 107: 20275-80. PMID 21057107 DOI: 10.1073/Pnas.1009860107  0.662
2010 Hoadley KA, Xu D, Xue Y, Satyshur KA, Wang W, Keck JL. Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure (London, England : 1993). 18: 1149-58. PMID 20826341 DOI: 10.1016/J.Str.2010.06.009  0.561
2010 Petrova V, Satyshur KA, George NP, McCaslin D, Cox MM, Keck JL. X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of RecA. The Journal of Biological Chemistry. 285: 30615-21. PMID 20659894 DOI: 10.1074/Jbc.M110.152298  0.786
2010 Hoadley KA, Keck JL. Werner helicase wings DNA binding. Structure (London, England : 1993). 18: 149-51. PMID 20159459 DOI: 10.1016/J.Str.2010.01.007  0.596
2010 Cox MM, Keck JL, Battista JR. Rising from the Ashes: DNA Repair in Deinococcus radiodurans. Plos Genetics. 6: e1000815. PMID 20084105 DOI: 10.1371/Journal.Pgen.1000815  0.61
2010 Lu D, Bernstein DA, Satyshur KA, Keck JL. Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance. Proceedings of the National Academy of Sciences of the United States of America. 107: 633-8. PMID 20018747 DOI: 10.1073/Pnas.0909191107  0.798
2010 Lindner SE, De Silva EK, Keck JL, Llinás M. Structural determinants of DNA binding by a P. falciparum ApiAP2 transcriptional regulator. Journal of Molecular Biology. 395: 558-67. PMID 19913037 DOI: 10.1016/J.Jmb.2009.11.004  0.827
2009 George NP, Keck JL. Molecular biology: Slip sliding on DNA. Nature. 461: 1067-8. PMID 19847254 DOI: 10.1038/4611067A  0.824
2009 Lu D, Windsor MA, Gellman SH, Keck JL. Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. Biochemistry. 48: 6764-71. PMID 19527069 DOI: 10.1021/Bi900361R  0.583
2009 Shereda RD, Reiter NJ, Butcher SE, Keck JL. Identification of the SSB binding site on E. coli RecQ reveals a conserved surface for binding SSB's C terminus. Journal of Molecular Biology. 386: 612-25. PMID 19150358 DOI: 10.1016/J.Jmb.2008.12.065  0.861
2009 Killoran MP, Kohler PL, Dillard JP, Keck JL. RecQ DNA helicase HRDC domains are critical determinants in Neisseria gonorrhoeae pilin antigenic variation and DNA repair. Molecular Microbiology. 71: 158-71. PMID 19017267 DOI: 10.1111/J.1365-2958.2008.06513.X  0.871
2008 Berndsen CE, Tsubota T, Lindner SE, Lee S, Holton JM, Kaufman PD, Keck JL, Denu JM. Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75. Nature Structural & Molecular Biology. 15: 948-56. PMID 19172748 DOI: 10.1038/Nsmb.1459  0.652
2008 Shereda RD, Kozlov AG, Lohman TM, Cox MM, Keck JL. SSB as an organizer/mobilizer of genome maintenance complexes. Critical Reviews in Biochemistry and Molecular Biology. 43: 289-318. PMID 18937104 DOI: 10.1080/10409230802341296  0.859
2008 Lu D, Keck JL. Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. Proceedings of the National Academy of Sciences of the United States of America. 105: 9169-74. PMID 18591666 DOI: 10.1073/Pnas.0800741105  0.682
2008 Carlson CB, Liu Y, Keck JL, Mosher DF. Influences of the N700S thrombospondin-1 polymorphism on protein structure and stability. The Journal of Biological Chemistry. 283: 20069-76. PMID 18499674 DOI: 10.1074/Jbc.M800223200  0.376
2008 Killoran MP, Keck JL. Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ. Nucleic Acids Research. 36: 3139-49. PMID 18411208 DOI: 10.1093/Nar/Gkn143  0.866
2007 Lopper M, Boonsombat R, Sandler SJ, Keck JL. A hand-off mechanism for primosome assembly in replication restart. Molecular Cell. 26: 781-93. PMID 17588514 DOI: 10.1016/J.Molcel.2007.05.012  0.873
2007 Shereda RD, Bernstein DA, Keck JL. A central role for SSB in Escherichia coli RecQ DNA helicase function. The Journal of Biological Chemistry. 282: 19247-58. PMID 17483090 DOI: 10.1074/Jbc.M608011200  0.867
2007 Gourse RL, Keck JL. Magic spots cast a spell on DNA primase. Cell. 128: 823-4. PMID 17350566 DOI: 10.1016/J.Cell.2007.02.020  0.526
2006 Killoran MP, Keck JL. Sit down, relax and unwind: structural insights into RecQ helicase mechanisms. Nucleic Acids Research. 34: 4098-105. PMID 16935877 DOI: 10.1093/Nar/Gkl538  0.84
2006 Hou Z, Danzer JR, Fox CA, Keck JL. Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution. Protein Science : a Publication of the Protein Society. 15: 1182-6. PMID 16641491 DOI: 10.1110/Ps.052061006  0.415
2006 Killoran MP, Keck JL. Three HRDC domains differentially modulate Deinococcus radiodurans RecQ DNA helicase biochemical activity. The Journal of Biological Chemistry. 281: 12849-57. PMID 16531400 DOI: 10.1074/Jbc.M600097200  0.872
2005 Zittel MC, Keck JL. Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence. Nucleic Acids Research. 33: 6982-91. PMID 16340008 DOI: 10.1093/Nar/Gki999  0.855
2005 Cadman CJ, Lopper M, Moon PB, Keck JL, McGlynn P. PriB stimulates PriA helicase via an interaction with single-stranded DNA. The Journal of Biological Chemistry. 280: 39693-700. PMID 16188886 DOI: 10.1074/Jbc.M508521200  0.872
2005 Carlson CB, Bernstein DA, Annis DS, Misenheimer TM, Hannah BL, Mosher DF, Keck JL. Structure of the calcium-rich signature domain of human thrombospondin-2. Nature Structural & Molecular Biology. 12: 910-4. PMID 16186819 DOI: 10.1038/nsmb997  0.66
2005 Bernstein DA, Keck JL. Conferring substrate specificity to DNA helicases: role of the RecQ HRDC domain. Structure (London, England : 1993). 13: 1173-82. PMID 16084389 DOI: 10.1016/J.Str.2005.04.018  0.806
2005 Wu L, Chan KL, Ralf C, Bernstein DA, Garcia PL, Bohr VA, Vindigni A, Janscak P, Keck JL, Hickson ID. The HRDC domain of BLM is required for the dissolution of double Holliday junctions. The Embo Journal. 24: 2679-87. PMID 15990871 DOI: 10.1038/Sj.Emboj.7600740  0.752
2005 Hou Z, Bernstein DA, Fox CA, Keck JL. Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing. Proceedings of the National Academy of Sciences of the United States of America. 102: 8489-94. PMID 15932939 DOI: 10.1073/Pnas.0503525102  0.698
2004 Lopper M, Holton JM, Keck JL. Crystal structure of PriB, a component of the Escherichia coli replication restart primosome. Structure (London, England : 1993). 12: 1967-75. PMID 15530361 DOI: 10.1016/J.Str.2004.09.004  0.879
2004 Bennett RJ, Keck JL. Structure and function of RecQ DNA helicases. Critical Reviews in Biochemistry and Molecular Biology. 39: 79-97. PMID 15217989 DOI: 10.1080/10409230490460756  0.743
2004 Bernstein DA, Eggington JM, Killoran MP, Misic AM, Cox MM, Keck JL. Crystal structure of the Deinococcus radiodurans single-stranded DNA-binding protein suggests a mechanism for coping with DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 101: 8575-80. PMID 15159541 DOI: 10.1073/Pnas.0401331101  0.854
2004 Bose ME, McConnell KH, Gardner-Aukema KA, Müller U, Weinreich M, Keck JL, Fox CA. The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Molecular and Cellular Biology. 24: 774-86. PMID 14701749 DOI: 10.1128/Mcb.24.2.774-786.2004  0.403
2003 Bernstein DA, Zittel MC, Keck JL. High-resolution structure of the E.coli RecQ helicase catalytic core. The Embo Journal. 22: 4910-21. PMID 14517231 DOI: 10.1093/Emboj/Cdg500  0.808
2003 Bernstein DA, Keck JL. Domain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ family. Nucleic Acids Research. 31: 2778-85. PMID 12771204 DOI: 10.1093/Nar/Gkg376  0.778
2001 Keck JL, Berger JM. Primus inter pares (first among equals). Nature Structural Biology. 8: 2-4. PMID 11135655 DOI: 10.1038/82996  0.729
2000 Goedken ER, Keck JL, Berger JM, Marqusee S. Divalent metal cofactor binding in the kinetic folding trajectory of Escherichia coli ribonuclease HI. Protein Science : a Publication of the Protein Society. 9: 1914-21. PMID 11106164 DOI: 10.1110/Ps.9.10.1914  0.797
2000 Keck JL, Roche DD, Lynch AS, Berger JM. Structure of the RNA polymerase domain of E. coli primase. Science (New York, N.Y.). 287: 2482-6. PMID 10741967 DOI: 10.1126/Science.287.5462.2482  0.766
2000 Keck JL, Berger JM. DNA replication at high resolution. Chemistry & Biology. 7: R63-71. PMID 10712935 DOI: 10.1016/S1074-5521(00)00094-6  0.764
1999 Nichols MD, DeAngelis K, Keck JL, Berger JM. Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11. The Embo Journal. 18: 6177-88. PMID 10545127 DOI: 10.1093/Emboj/18.21.6177  0.78
1999 Keck JL, Berger JM. Enzymes that push DNA around. Nature Structural Biology. 6: 900-2. PMID 10504717 DOI: 10.1038/13260  0.802
1999 Bennett RJ, Keck JL, Wang JC. Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae. Journal of Molecular Biology. 289: 235-48. PMID 10366502 DOI: 10.1006/Jmbi.1999.2739  0.833
1998 Keck JL, Goedken ER, Marqusee S. Activation/attenuation model for RNase H. A one-metal mechanism with second-metal inhibition. The Journal of Biological Chemistry. 273: 34128-33. PMID 9852071 DOI: 10.1074/Jbc.273.51.34128  0.77
1997 Keck JL, Marqusee S. Metal activation and regulation of E. coli RNase H Techniques in Protein Chemistry. 8: 409-416. DOI: 10.1016/S1080-8914(97)80041-5  0.605
1996 Keck JL, Marqusee S. The putative substrate recognition loop of Escherichia coli ribonuclease H is not essential for activity. The Journal of Biological Chemistry. 271: 19883-7. PMID 8702700 DOI: 10.1074/Jbc.271.33.19883  0.623
1995 Keck JL, Marqusee S. Substitution of a highly basic helix/loop sequence into the RNase H domain of human immunodeficiency virus reverse transcriptase restores its Mn(2+)-dependent RNase H activity. Proceedings of the National Academy of Sciences of the United States of America. 92: 2740-4. PMID 7535929 DOI: 10.1073/Pnas.92.7.2740  0.589
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