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Peter Kirwan, B.A., M.Phil - Publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
Cortical circuitry, pluripotent stem cells
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sonoyama T, Stadler LKJ, Zhu M, Keogh JM, Henning E, Hisama F, Kirwan P, Jura M, Blaszczyk BK, DeWitt DC, Brouwers B, Hyvönen M, Barroso I, Merkle FT, Appleyard SM, et al. Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities. Scientific Reports. 10: 9028. PMID 32493978 DOI: 10.1038/S41598-020-65531-X  0.36
2019 Razolli D, de Araújo T, Sant'Ana M, Kirwan P, Cintra D, Merkle F, Velloso L. POMC processing in the hypothalamus is directly regulated by saturated fat - implications for the development of obesity. Neuroendocrinology. PMID 31104058 DOI: 10.1159/000501023  0.326
2018 Kirwan P, Kay RG, Brouwers B, Herranz-Pérez V, Jura M, Larraufie P, Jerber J, Pembroke J, Bartels T, White A, Gribble FM, Reimann F, Farooqi IS, O'Rahilly S, Merkle FT. Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis. Molecular Metabolism. PMID 30201275 DOI: 10.1016/J.Molmet.2018.08.006  0.318
2018 Heeley N, Kirwan P, Darwish T, Arnaud M, Evans ML, Merkle FT, Reimann F, Gribble FM, Blouet C. Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights. Molecular Metabolism. PMID 29439854 DOI: 10.1016/J.Molmet.2018.01.021  0.436
2017 Kirwan P, Jura M, Merkle FT. Generation and Characterization of Functional Human Hypothalamic Neurons. Current Protocols in Neuroscience. 81: 3.33.1-3.33.24. PMID 29064566 DOI: 10.1002/Cpns.40  0.49
2015 Kirwan P, Turner-Bridger B, Peter M, Momoh A, Arambepola D, Robinson HP, Livesey FJ. Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro. Development (Cambridge, England). 142: 3178-87. PMID 26395144 DOI: 10.1242/Dev.123851  0.604
2015 Moore S, Evans LD, Andersson T, Portelius E, Smith J, Dias TB, Saurat N, McGlade A, Kirwan P, Blennow K, Hardy J, Zetterberg H, Livesey FJ. APP metabolism regulates tau proteostasis in human cerebral cortex neurons. Cell Reports. 11: 689-96. PMID 25921538 DOI: 10.1016/J.Celrep.2015.03.068  0.545
2014 Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A. The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development (Cambridge, England). 141: 2216-24. PMID 24821983 DOI: 10.1242/Dev.106377  0.644
2012 Shi Y, Kirwan P, Livesey FJ. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nature Protocols. 7: 1836-46. PMID 22976355 DOI: 10.1038/Nprot.2012.116  0.659
2012 Shi Y, Kirwan P, Smith J, MacLean G, Orkin SH, Livesey FJ. A human stem cell model of early Alzheimer's disease pathology in Down syndrome. Science Translational Medicine. 4: 124ra29. PMID 22344463 DOI: 10.1126/Scitranslmed.3003771  0.677
2012 Shi Y, Kirwan P, Smith J, Robinson HP, Livesey FJ. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nature Neuroscience. 15: 477-86, S1. PMID 22306606 DOI: 10.1038/Nn.3041  0.638
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