Gloria M. Coruzzi, Ph.D

Affiliations: 
1984-1991 Lab of Plant Molecular Biology Rockefeller University, New York, NY, United States 
 1991- Center for Genomics & Systems Biology New York University, New York, NY, United States 
Area:
Plant Systems Biology
Website:
http://coruzzilab.bio.nyu.edu/
Google:
"Gloria Coruzzi"
Bio:

http://www.nasonline.org/member-directory/members/20044143.html
https://as.nyu.edu/content/dam/nyu-as/faculty/documents/coruzzi-gloria-cv.pdf
https://scholar.google.com/citations?user=UVuQeJIAAAAJ&hl=en
Bio-sketch: (also see Wikipedia https://en.wikipedia.org/wiki/Gloria_M._Coruzzi).
Dr. Coruzzi is currently the Carroll & Milton Petrie Professor at New York University’s Center for Genomics and Systems Biology. Her research in Plant Systems Biology combines genomic, bioinformatic, and system biology approaches to identify gene networks involved in biological regulatory mechanisms controlling nitrogen use efficiency. A native New Yorker, Dr. Coruzzi received her Ph.D. in Molecular & Cell Biology at New York University School of Medicine in yeast genetics, where she decoded the yeast mitochondrial genome. These studies revealed that TGA codes for tryptophan in yeast mitochondria, a discovery subsequently found in humans. As post-doctoral fellow at Rockefeller University (1980-83), she began studies of plant molecular biology by cloning one of the first plant nuclear genes. As an Assistant and then Associate Professor at Rockefeller University, Dr. Coruzzi began her studies of the genes in the nitrogen assimilatory pathway. Since joining NYU as the Carroll & Milton Petrie Professor of Biology in 1991, Dr. Coruzzi’s lab has initiated genomic and systems biology approaches in Arabidopsis and crop species to study gene regulatory networks underlying Nitrogen Use Efficiency. This work has included the development of new bioinformatic and systems biology approaches. The over-arching achievement of Dr. Coruzzi’s research has been to develop Systems Biology approaches to predictively model how internal and external perturbations affect processes, pathways & networks controlling plant metabolism, growth and development. Her current studies exploit time - the 4th and largely unexplored dimension of transcriptional networks - to temporally perturb TF function and to predict and validate dynamic gene regulatory (GRNs) models that can forecast network states at future time-points, a major goal of systems biology. Dr. Coruzzi’s system biology studies involve collaborations with colleagues at NYU Courant Institute for Math & Computer Science. Dr. Coruzzi is also engaged in a collaborative NSF Plant Genome Project on the Comparative Genomics of Seed Evolution with co-PIs at the New York Botanical Garden, the American Museum of Natural History, and Cold Spring Harbor labs. Dr. Coruzzi’s research is funded by the National Institutes of Health, the NSF Plant Genome Program, the Department of Energy and the Zegar Family Foundation. Dr. Coruzzi was named an American Association for the Advancement of Science Fellow in 2005, a Fellow of the American Society of Plant Biology in 2010, was awarded the ASPB Stephen Hales Prize in 2015, was named Distinguished Counselor to the Board, The New York Botanical Garden in 2017, and was elected to the National Academy of Sciences, Plant Biology Section in 2019. Coruzzi currently serves on several science editorial boards including; The Proceedings of the National Academy of Science, G3: Genes, Genomes and Genetics, and scientific advisory boards including the DOE Joint Genome Institute (JGI) Scientific Advisory Committee and their Plant Program Advisory Board. In addition to her research, Prof. Coruzzi is devoted to mentoring undergraduate and high school STEM students to apply computational approaches to biology.
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Parents

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Alexander Tzagoloff grad student 1976-1979 NYU School of Medicine (Chemistry Tree)
 (Genetic and biochemical analysis of mitochondrial DNA)
Nam-Hai Chua post-doc 1980-1983 Rockefeller

Children

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Anna-Lena Schinke grad student NYU
Joseph Swift grad student Salk Institute, La Jolla, California
Eduardo dela Torre grad student Baruch College/CUNY
Elsbeth L. Walker grad student U Mass Amherst
Carolyn Schultz grad student 1992- University of Adelaide, Australia
Rosana Melo grad student 1999- Bayer
Fong-Ying Tsai grad student 1990 Rockefeller
Michael Shin grad student 1994 NYU
Ming-Hsiun Hsieh grad student 1995 Academia Sinica
Barbara H. Miesak More grad student 2002 NYU
Lisa Franchi grad student 2003 NYU
Nyree J. Zerega grad student 2003 NYU
Joanna C. Chiu grad student 2004 NYU
Chelsea D. Specht grad student 2004 NYU (Evolution Tree)
Lauren Raz grad student 2007 NYU
Damion Nero grad student 2009 NYU (Computational Biology Tree)
Daniela Ristova grad student 2013 NYU
Joseph Swift grad student 2018 Salk Institute, San Diego
Eleonore Bouyguon post-doc University of La Reunion
Timothy Brears post-doc Evonetix
Eric Brenner post-doc Pace University
Matthew Brooks post-doc NYU
Chia-Yi Cheng post-doc NYU
Joan Doidy post-doc University de Poitiers
Janice Edwards post-doc Bayer AG
Ji Huang post-doc NYU
Angelica Cibrian Jaramillo post-doc CINVESTAV
Manpreet S. Katari post-doc NYU (Cell Biology Tree)
Andrei Kouranov post-doc Monsanto
Gabriel Krouk post-doc B&PMP Montpellier
Laurence Lejay post-doc B&PMP Montpellier
Sophie Leran post-doc CIRAD
Ying Li post-doc Purdue
Amy Marshall-Colon post-doc UIUC (Chemistry Tree)
Lee Ann Meisel post-doc University of Chile
Mariana Obertello post-doc University of Argentina
Peter M. Palenchar post-doc University of Delaware (Chemistry Tree)
Alessia Para post-doc Northwestern
Sandrine Ruffel post-doc B&PMP Montpellier
Carly Shanks post-doc NYU
Scott Tingey post-doc DuPont Co.
Reetu Tuteja post-doc CyVerse
Kranthi Varala post-doc Purdue
Hon-Ming Lam post-doc 1992-1996 NYU
Rodrigo Gutierrez post-doc 2003-2006 Pontificia Universidad Católica de Chile Santiago, Chile
Karen E. Thum post-doc 2001-2007 NYU (Chemistry Tree)
Miriam Louise Gifford post-doc 2005-2009 NYU
Ying Li post-doc 2011-2016
Jose Miguel Alvarez post-doc 2020 NYU
Viviana Araus post-doc 2020 NYU

Collaborators

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Rob DeSalle collaborator American Museum of Natural History (FlyTree)
Rodrigo Gutierrez collaborator P Universidad Catolica de Chile
Gabriel Krouk collaborator B&PMP Montpellier
R.W. McCombie collaborator CSHL
Stephen Moose collaborator UIUC (Cell Biology Tree)
Sandrine Ruffel collaborator B&PMP Montpellier
Dennis Shasha collaborator NYU Courant (Computational Biology Tree)
Dennis William Stevenson collaborator New York Botanical Garden (Evolution Tree)
BETA: Related publications

Publications

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Hinckley WE, Jack A, Li A, et al. (2025) Transcription Factor (TF) validation using Dam-IT simultaneously captures genome-wide TF-DNA binding, direct gene regulation, and chromatin accessibility in plant cells. Biorxiv : the Preprint Server For Biology
Ruffel S, Del Rosario J, Lacombe B, et al. (2025) Nitrate Sensing and Signaling in Plants: Comparative Insights and Nutritional Interactions. Annual Review of Plant Biology. 76: 25-52
Huang J, Cheng CY, Brooks MD, et al. (2025) NUE regulons conserved model-to-crop enhance machine learning predictions of nitrogen use efficiency. The Plant Cell
Salinas NR, Eshel G, Coruzzi GM, et al. (2024) BAD2matrix: Phylogenomic matrix concatenation, indel coding, and more. Applications in Plant Sciences. 12: e11604
Shen B, Coruzzi GM, Shasha D. (2024) Corrigendum: Bipartite networks represent causality better than simple networks: Evidence, algorithms, and applications. Frontiers in Genetics. 15: 1440665
Dussarrat T, Nilo-Poyanco R, Moyano TC, et al. (2024) Phylogenetically diverse wild plant species use common biochemical strategies to thrive in the Atacama Desert. Journal of Experimental Botany
Shanks CM, Rothkegel K, Brooks MD, et al. (2024) Nitrogen sensing and regulatory networks: It's about time and space. The Plant Cell
Coruzzi GM, Birnbaum KD. (2023) Philip N. Benfey (1953-2023). Science (New York, N.Y.). 382: 1127
Raikhel N, Ecker JR, Coruzzi G. (2023) Remembering Philip N. Benfey: A visionary pioneer in plant biology and mentor extraordinaire. Proceedings of the National Academy of Sciences of the United States of America. 120: e2317677120
Huang J, Katari MS, Juang CL, et al. (2023) Building High-Confidence Gene Regulatory Networks by Integrating Validated TF-Target Gene Interactions Using ConnecTF. Methods in Molecular Biology (Clifton, N.J.). 2698: 195-220
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