| Year |
Citation |
Score |
| 2025 |
Dong J, Croslow SW, Lane ST, Castro DC, Blanford J, Zhou S, Park K, Burgess S, Root M, Cahoon E, Shanklin J, Sweedler JV, Zhao H, Hudson ME. Enhancing lipid production in plant cells through automated high-throughput genome editing and phenotyping. The Plant Cell. PMID 39899469 DOI: 10.1093/plcell/koaf026 |
0.538 |
|
| 2024 |
Liu H, Blanford J, Shi H, Schwender J, Shanklin J, Zhai Z. The Target of Rapamycin kinase is a positive regulator of plant fatty acid and lipid synthesis. Plant Physiology. PMID 39739868 DOI: 10.1093/plphys/kiae639 |
0.369 |
|
| 2024 |
Fan J, Sah SK, Lemes Jorge G, Blanford J, Xie D, Yu L, Thelen J, Shanklin J, Xu C. Arabidopsis trigalactosyldiacylglycerol1 mutants reveal a critical role for phosphtidylcholine remodeling in lipid homeostasis. The Plant Journal : For Cell and Molecular Biology. PMID 39276345 DOI: 10.1111/tpj.17020 |
0.35 |
|
| 2024 |
Cai Y, Liang Y, Shi H, Cui J, Prakash S, Zhang J, Anaokar S, Chai J, Schwender J, Lu C, Yu XH, Shanklin J. Creating yellow seed Camelina sativa with enhanced oil accumulation by CRISPR-mediated disruption of Transparent Testa 8. Plant Biotechnology Journal. PMID 38859598 DOI: 10.1111/pbi.14403 |
0.314 |
|
| 2022 |
Liang Y, Yu XH, Anaokar S, Shi H, Dahl WB, Cai Y, Luo G, Chai J, Cai Y, Mollá-Morales A, Altpeter F, Ernst E, Schwender J, Martienssen RA, Shanklin J. Engineering Triacylglycerol Accumulation in Duckweed (Lemna japonica). Plant Biotechnology Journal. PMID 36209479 DOI: 10.1111/pbi.13943 |
0.346 |
|
| 2022 |
Gan L, Park K, Chai J, Updike EM, Kim H, Voshall A, Behera S, Yu XH, Cai Y, Zhang C, Wilson MA, Mower JP, Moriyama EN, Zhang C, Kaewsuwan S, ... ... Shanklin J, et al. Divergent evolution of extreme production of variant plant monounsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201160119. PMID 35867834 DOI: 10.1073/pnas.2201160119 |
0.654 |
|
| 2022 |
Cai Y, Zhai Z, Blanford J, Liu H, Shi H, Schwender J, Xu C, Shanklin J. Purple acid phosphatase2 stimulates a futile cycle of lipid synthesis and degradation, and mitigates the negative growth effects of triacylglycerol accumulation in vegetative tissues. The New Phytologist. PMID 35851483 DOI: 10.1111/nph.18392 |
0.306 |
|
| 2021 |
Voshall A, Behera S, Li X, Yu XH, Kapil K, Deogun JS, Shanklin J, Cahoon EB, Moriyama EN. A consensus-based ensemble approach to improve transcriptome assembly. Bmc Bioinformatics. 22: 513. PMID 34674629 DOI: 10.1186/s12859-021-04434-8 |
0.485 |
|
| 2021 |
Yu XH, Cai Y, Keereetaweep J, Wei K, Chai J, Deng E, Liu H, Shanklin J. Corrigendum to: Biotin attachment domain-containing proteins mediate hydroxy fatty acid-dependent inhibition of acetyl CoA carboxylase. Plant Physiology. PMID 34623451 DOI: 10.1093/plphys/kiab107 |
0.312 |
|
| 2021 |
Zhai Z, Keereetaweep J, Liu H, Xu C, Shanklin J. The Role of Sugar Signaling in Regulating Plant Fatty Acid Synthesis. Frontiers in Plant Science. 12: 643843. PMID 33828577 DOI: 10.3389/fpls.2021.643843 |
0.307 |
|
| 2021 |
Yu XH, Cai Y, Keereetaweep J, Wei K, Chai J, Deng E, Liu H, Shanklin J. Biotin attachment domain-containing proteins mediate hydroxy fatty acid-dependent inhibition of acetyl CoA carboxylase. Plant Physiology. PMID 33793910 DOI: 10.1093/plphys/kiaa109 |
0.373 |
|
| 2021 |
Zhai Z, Keereetaweep J, Liu H, Feil R, Lunn JE, Shanklin J. Expression of a Bacterial Trehalose-6-phosphate Synthase otsA Increases Oil Accumulation in Plant Seeds and Vegetative Tissues. Frontiers in Plant Science. 12: 656962. PMID 33777087 DOI: 10.3389/fpls.2021.656962 |
0.361 |
|
| 2021 |
Baer MD, Shanklin J, Raugei S. Atomistic insight on structure and dynamics of spinach acyl carrier protein with substrate length. Biophysical Journal. PMID 33631202 DOI: 10.1016/j.bpj.2020.12.036 |
0.354 |
|
| 2020 |
Yu XH, Shanklin J. Solving a furan fatty acid biosynthesis puzzle. The Journal of Biological Chemistry. 295: 9802-9803. PMID 32680970 DOI: 10.1074/Jbc.H120.014701 |
0.446 |
|
| 2020 |
Cai Y, Yu XH, Chai J, Liu CJ, Shanklin J. A conserved evolutionary mechanism permits Δ9 desaturation of very long chain fatty acyl lipids. The Journal of Biological Chemistry. PMID 32527722 DOI: 10.1074/Jbc.Ra120.014258 |
0.412 |
|
| 2020 |
Royer J, Shanklin J, Balch-Kenney N, Mayorga M, Houston P, de Jong RM, McMahon J, Laprade L, Blomquist P, Berry T, Cai Y, LoBuglio K, Trueheart J, Chevreux B. Rhodoxanthin synthase from honeysuckle; a membrane diiron enzyme catalyzes the multistep conversation of β-carotene to rhodoxanthin. Science Advances. 6: eaay9226. PMID 32426461 DOI: 10.1126/Sciadv.Aay9226 |
0.326 |
|
| 2019 |
Whittle EJ, Cai Y, Keereetaweep J, Chai J, Buist PH, Shanklin J. Castor Stearoyl-ACP Desaturase Can Synthesize a Vicinal Diol by Dioxygenase Chemistry. Plant Physiology. PMID 31806737 DOI: 10.1104/Pp.19.01111 |
0.363 |
|
| 2019 |
Liu H, Zhai Z, Kuczynski K, Keereetaweep J, Schwender J, Shanklin J. WRINKLED1 regulates BIOTIN ATTACHMENT DOMAIN-CONTAINING proteins that inhibit fatty acid synthesis. Plant Physiology. PMID 31209126 DOI: 10.1104/Pp.19.00587 |
0.447 |
|
| 2019 |
Yu XH, Cai Y, Chai J, Schwender J, Shanklin J. Expression of a Lychee PHOSPHATIDYLCHOLINE:DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE with an E. coli CYCLOPROPANE SYNTHASE Enhances Cyclopropane Fatty Acid Accumulation in Camelina Seeds. Plant Physiology. PMID 31123096 DOI: 10.1104/Pp.19.00396 |
0.473 |
|
| 2019 |
Sturtevant D, Romsdahl TB, Yu XH, Burks DJ, Azad RK, Shanklin J, Chapman KD. Tissue-specific differences in metabolites and transcripts contribute to the heterogeneity of ricinoleic acid accumulation in Ricinus communis L. (castor) seeds. Metabolomics : Official Journal of the Metabolomic Society. 15: 6. PMID 30830477 DOI: 10.1007/S11306-018-1464-3 |
0.44 |
|
| 2018 |
Cai Y, Yu XH, Liu Q, Liu CJ, Shanklin J. Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin. The Journal of Biological Chemistry. PMID 30348899 DOI: 10.1074/Jbc.Ra118.005972 |
0.343 |
|
| 2018 |
Zhai Z, Keereetaweep J, Liu H, Feil R, Lunn JE, Shanklin J. Trehalose 6-phosphate positively regulates fatty acid biosynthesis by stabilizing WRINKLED1. The Plant Cell. PMID 30249634 DOI: 10.1105/Tpc.18.00521 |
0.411 |
|
| 2018 |
Keereetaweep J, Liu H, Zhai Z, Shanklin J. Biotin Attachment Domain-Containing Proteins Irreversibly Inhibit Acetyl CoA Carboxylase. Plant Physiology. PMID 29626162 DOI: 10.1104/Pp.18.00216 |
0.476 |
|
| 2017 |
Yu XH, Cahoon RE, Horn PJ, Shi H, Prakash RR, Cai Y, Hearney M, Chapman KD, Cahoon EB, Schwender J, Shanklin J. Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil. Plant Biotechnology Journal. PMID 28929610 DOI: 10.1111/Pbi.12839 |
0.661 |
|
| 2017 |
Zhai Z, Liu H, Xu C, Shanklin J. Sugar Potentiation of Fatty Acid and Triacylglycerol Accumulation. Plant Physiology. PMID 28842550 DOI: 10.1104/Pp.17.00828 |
0.39 |
|
| 2017 |
Zhai Z, Liu H, Shanklin J. Phosphorylation of WRINKLED1 by KIN10 Results in its Proteasomal Degradation, Providing a Link Between Energy Homeostasis and Lipid Biosynthesis. The Plant Cell. PMID 28314829 DOI: 10.1105/Tpc.17.00019 |
0.367 |
|
| 2016 |
Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF, et al. A family of metal-dependent phosphatases implicated in metabolite damage-control. Nature Chemical Biology. PMID 27322068 DOI: 10.1038/Nchembio.2108 |
0.341 |
|
| 2016 |
Sedeek KE, Whittle E, Guthörl D, Grossniklaus U, Shanklin J, Schlüter PM. Amino Acid Change in an Orchid Desaturase Enables Mimicry of the Pollinator's Sex Pheromone. Current Biology : Cb. 26: 1505-11. PMID 27212404 DOI: 10.1016/J.Cub.2016.04.018 |
0.414 |
|
| 2016 |
Xu C, Andre C, Fan J, Shanklin J. Cellular Organization of Triacylglycerol Biosynthesis in Microalgae. Sub-Cellular Biochemistry. 86: 207-221. PMID 27023237 DOI: 10.1007/978-3-319-25979-6_9 |
0.308 |
|
| 2016 |
Xu C, Shanklin J. Triacylglycerol Metabolism, Function, and Accumulation in Plant Vegetative Tissues. Annual Review of Plant Biology. PMID 26845499 DOI: 10.1146/Annurev-Arplant-043015-111641 |
0.372 |
|
| 2015 |
Provart NJ, Alonso J, Assmann SM, Bergmann D, Brady SM, Brkljacic J, Browse J, Chapple C, Colot V, Cutler S, Dangl J, Ehrhardt D, Friesner JD, Frommer WB, Grotewold E, ... ... Shanklin J, et al. 50 years of Arabidopsis research: highlights and future directions. The New Phytologist. PMID 26465351 DOI: 10.1111/Nph.13687 |
0.702 |
|
| 2015 |
Cai Y, Bhuiya MW, Shanklin J, Liu CJ. Engineering a Monolignol 4-O-methyltransferase with High Selectivity for the Condensed Lignin Precursor Coniferyl Alchohol. The Journal of Biological Chemistry. PMID 26378240 DOI: 10.1074/Jbc.M115.684217 |
0.371 |
|
| 2015 |
Liu Q, Chai J, Moche M, Guy J, Lindqvist Y, Shanklin J. Half-of-the-Sites Reactivity of the Castor Δ9-18:0-Acyl Carrier Protein Desaturase. Plant Physiology. 169: 432-41. PMID 26224800 DOI: 10.1104/Pp.15.00622 |
0.411 |
|
| 2015 |
Coursolle D, Lian J, Shanklin J, Zhao H. Production of long chain alcohols and alkanes upon coexpression of an acyl-ACP reductase and aldehyde-deformylating oxygenase with a bacterial type-I fatty acid synthase in E. coli. Molecular Biosystems. 11: 2464-72. PMID 26135500 DOI: 10.1039/C5Mb00268K |
0.417 |
|
| 2015 |
Zale J, Jung JH, Kim JY, Pathak B, Karan R, Liu H, Chen X, Wu H, Candreva J, Zhai Z, Shanklin J, Altpeter F. Metabolic engineering of sugarcane to accumulate energy-dense triacylglycerols in vegetative biomass. Plant Biotechnology Journal. PMID 26058948 DOI: 10.1111/Pbi.12411 |
0.408 |
|
| 2015 |
Nguyen HT, Park H, Koster KL, Cahoon RE, Nguyen HT, Shanklin J, Clemente TE, Cahoon EB. Redirection of metabolic flux for high levels of omega-7 monounsaturated fatty acid accumulation in camelina seeds. Plant Biotechnology Journal. 13: 38-50. PMID 25065607 DOI: 10.1111/Pbi.12233 |
0.665 |
|
| 2014 |
Fan J, Yan C, Roston R, Shanklin J, Xu C. Arabidopsis lipins, PDAT1 acyltransferase, and SDP1 triacylglycerol lipase synergistically direct fatty acids toward β-oxidation, thereby maintaining membrane lipid homeostasis. The Plant Cell. 26: 4119-34. PMID 25293755 DOI: 10.1105/Tpc.114.130377 |
0.4 |
|
| 2014 |
Lou Y, Schwender J, Shanklin J. FAD2 and FAD3 desaturases form heterodimers that facilitate metabolic channeling in vivo. The Journal of Biological Chemistry. 289: 17996-8007. PMID 24811169 DOI: 10.1074/Jbc.M114.572883 |
0.46 |
|
| 2014 |
Wang W, Haberer G, Gundlach H, Gläßer C, Nussbaumer T, Luo MC, Lomsadze A, Borodovsky M, Kerstetter RA, Shanklin J, Byrant DW, Mockler TC, Appenroth KJ, Grimwood J, Jenkins J, et al. The Spirodela polyrhiza genome reveals insights into its neotenous reduction fast growth and aquatic lifestyle. Nature Communications. 5: 3311. PMID 24548928 DOI: 10.1038/Ncomms4311 |
0.31 |
|
| 2014 |
Yu XH, Prakash RR, Sweet M, Shanklin J. Coexpressing Escherichia coli cyclopropane synthase with Sterculia foetida Lysophosphatidic acid acyltransferase enhances cyclopropane fatty acid accumulation. Plant Physiology. 164: 455-65. PMID 24204024 DOI: 10.1104/Pp.113.230953 |
0.47 |
|
| 2013 |
Yan Y, Candreva J, Shi H, Ernst E, Martienssen R, Schwender J, Shanklin J. Survey of the total fatty acid and triacylglycerol composition and content of 30 duckweed species and cloning of a Δ6-desaturase responsible for the production of γ-linolenic and stearidonic acids in Lemna gibba. Bmc Plant Biology. 13: 201. PMID 24308551 DOI: 10.1186/1471-2229-13-201 |
0.442 |
|
| 2013 |
Parks BM, Shanklin J, Koornneef M, Kendrick RE, Quail PH. Immunochemically detectable phytochrome is present at normal levels but is photochemically nonfunctional in the hy 1 and hy 2 long hypocotyl mutants of Arabidopsis. Plant Molecular Biology. 12: 425-37. PMID 24272903 DOI: 10.1007/Bf00017582 |
0.332 |
|
| 2013 |
Andre C, Kim SW, Yu XH, Shanklin J. Fusing catalase to an alkane-producing enzyme maintains enzymatic activity by converting the inhibitory byproduct H2O2 to the cosubstrate O2. Proceedings of the National Academy of Sciences of the United States of America. 110: 3191-6. PMID 23391732 DOI: 10.1073/Pnas.1218769110 |
0.356 |
|
| 2012 |
Andre C, Haslam RP, Shanklin J. Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus. Proceedings of the National Academy of Sciences of the United States of America. 109: 10107-12. PMID 22665812 DOI: 10.1073/Pnas.1204604109 |
0.478 |
|
| 2012 |
Fan J, Yan C, Andre C, Shanklin J, Schwender J, Xu C. Oil accumulation is controlled by carbon precursor supply for fatty acid synthesis in Chlamydomonas reinhardtii. Plant & Cell Physiology. 53: 1380-90. PMID 22642988 DOI: 10.1093/Pcp/Pcs082 |
0.313 |
|
| 2012 |
Rawat R, Yu XH, Sweet M, Shanklin J. Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugase. The Journal of Biological Chemistry. 287: 16230-7. PMID 22451660 DOI: 10.1074/Jbc.M111.325316 |
0.464 |
|
| 2011 |
Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J. Remote control of regioselectivity in acyl-acyl carrier protein-desaturases. Proceedings of the National Academy of Sciences of the United States of America. 108: 16594-9. PMID 21930947 DOI: 10.1073/Pnas.1110221108 |
0.423 |
|
| 2011 |
Chen W, Yu XH, Zhang K, Shi J, De Oliveira S, Schreiber L, Shanklin J, Zhang D. Male Sterile2 encodes a plastid-localized fatty acyl carrier protein reductase required for pollen exine development in Arabidopsis. Plant Physiology. 157: 842-53. PMID 21813653 DOI: 10.1104/Pp.111.181693 |
0.317 |
|
| 2011 |
Shi J, Tan H, Yu XH, Liu Y, Liang W, Ranathunge K, Franke RB, Schreiber L, Wang Y, Kai G, Shanklin J, Ma H, Zhang D. Defective pollen wall is required for anther and microspore development in rice and encodes a fatty acyl carrier protein reductase. The Plant Cell. 23: 2225-46. PMID 21705642 DOI: 10.1105/Tpc.111.087528 |
0.431 |
|
| 2011 |
Yu XH, Rawat R, Shanklin J. Characterization and analysis of the cotton cyclopropane fatty acid synthase family and their contribution to cyclopropane fatty acid synthesis. Bmc Plant Biology. 11: 97. PMID 21612656 DOI: 10.1186/1471-2229-11-97 |
0.459 |
|
| 2011 |
Schlüter PM, Xu S, Gagliardini V, Whittle E, Shanklin J, Grossniklaus U, Schiestl FP. Stearoyl-acyl carrier protein desaturases are associated with floral isolation in sexually deceptive orchids. Proceedings of the National Academy of Sciences of the United States of America. 108: 5696-701. PMID 21436056 DOI: 10.1073/Pnas.1013313108 |
0.346 |
|
| 2010 |
Nguyen HT, Mishra G, Whittle E, Bevan SA, Merlo AO, Walsh TA, Shanklin J. Metabolic engineering of seeds can achieve levels of ω-7 fatty acids comparable with the highest levels found in natural plant sources Plant Physiology. 154: 1897-1904. PMID 20943853 DOI: 10.1104/Pp.110.165340 |
0.431 |
|
| 2010 |
Lou Y, Shanklin J. Evidence that the yeast desaturase Ole1p exists as a dimer in vivo. The Journal of Biological Chemistry. 285: 19384-90. PMID 20406812 DOI: 10.1074/Jbc.M110.125377 |
0.381 |
|
| 2010 |
Jabben M, Shanklin J, Vierstra RD. Red light-induced accumulation of ubiquitin-phytochrome conjugates in both monocots and dicots. Plant Physiology. 90: 380-4. PMID 16666778 DOI: 10.1104/Pp.90.2.380 |
0.302 |
|
| 2009 |
Shanklin J, Guy JE, Mishra G, Lindqvist Y. Desaturases: emerging models for understanding functional diversification of diiron-containing enzymes. The Journal of Biological Chemistry. 284: 18559-63. PMID 19363032 DOI: 10.1074/Jbc.R900009200 |
0.35 |
|
| 2009 |
Nguyen T, Shanklin J. Altering Arabidopsis Oilseed Composition by a Combined Antisense-Hairpin RNAi Gene Suppression Approach Journal of the American Oil Chemists' Society. 86: 41-49. DOI: 10.1007/S11746-008-1322-Y |
0.301 |
|
| 2008 |
Whittle EJ, Tremblay AE, Buist PH, Shanklin J. Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 105: 14738-43. PMID 18796606 DOI: 10.1073/Pnas.0805645105 |
0.483 |
|
| 2008 |
Zhang P, Burton JW, Upchurch RG, Whittle E, Shanklin J, Dewey RE. Mutations in a Δ9-stearoyl-ACP-desaturase gene are associated with enhanced stearic acid levels in soybean seeds Crop Science. 48: 2305-2313. DOI: 10.2135/Cropsci2008.02.0084 |
0.442 |
|
| 2007 |
Guy JE, Whittle E, Kumaran D, Lindqvist Y, Shanklin J. The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity. The Journal of Biological Chemistry. 282: 19863-71. PMID 17463003 DOI: 10.1074/Jbc.M702520200 |
0.348 |
|
| 2007 |
Pidkowich MS, Nguyen HT, Heilmann I, Ischebeck T, Shanklin J. Modulating seed beta-ketoacyl-acyl carrier protein synthase II level converts the composition of a temperate seed oil to that of a palm-like tropical oil. Proceedings of the National Academy of Sciences of the United States of America. 104: 4742-7. PMID 17360594 DOI: 10.1073/Pnas.0611141104 |
0.402 |
|
| 2007 |
Mayer KM, Shanklin J. Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach. Bmc Plant Biology. 7: 1. PMID 17201914 DOI: 10.1186/1471-2229-7-1 |
0.479 |
|
| 2007 |
Kachroo A, Shanklin J, Whittle E, Lapchyk L, Hildebrand D, Kachroo P. The Arabidopsis stearoyl-acyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis. Plant Molecular Biology. 63: 257-71. PMID 17072561 DOI: 10.1007/S11103-006-9086-Y |
0.466 |
|
| 2007 |
Shanklin J. Corrigendum to “Overexpression and purification of the Escherichia coli inner membrane enzyme acyl–acyl carrier protein synthase in an active form” [Protein Express. Purif. 18 (2000) 355–360] Protein Expression and Purification. 52: 485. DOI: 10.1016/J.Pep.2006.11.008 |
0.354 |
|
| 2006 |
Guy JE, Abreu IA, Moche M, Lindqvist Y, Whittle E, Shanklin J. A single mutation in the castor Delta9-18:0-desaturase changes reaction partitioning from desaturation to oxidase chemistry. Proceedings of the National Academy of Sciences of the United States of America. 103: 17220-4. PMID 17088542 DOI: 10.1073/Pnas.0607165103 |
0.403 |
|
| 2006 |
Tremblay AE, Buist PH, Hodgson D, Dawson B, Whittle E, Shanklin J. In vitro enzymatic oxidation of a fluorine-tagged sulfido substrate analogue: a 19F NMR investigation. Magnetic Resonance in Chemistry : Mrc. 44: 629-32. PMID 16534835 DOI: 10.1002/Mrc.1797 |
0.302 |
|
| 2005 |
Mayer KM, McCorkle SR, Shanklin J. Linking enzyme sequence to function using Conserved Property Difference Locator to identify and annotate positions likely to control specific functionality. Bmc Bioinformatics. 6: 284. PMID 16318626 DOI: 10.1186/1471-2105-6-284 |
0.355 |
|
| 2005 |
Whittle E, Cahoon EB, Subrahmanyam S, Shanklin J. A multifunctional acyl-acyl carrier protein desaturase from Hedera helix L. (English ivy) can synthesize 16- and 18-carbon monoene and diene products. The Journal of Biological Chemistry. 280: 28169-76. PMID 15939740 DOI: 10.1074/Jbc.M504205200 |
0.63 |
|
| 2005 |
Davydov R, Behrouzian B, Smoukov S, Stubbe J, Hoffman BM, Shanklin J. Effect of substrate on the diiron(III) site in stearoyl acyl carrier protein Δ9-desaturase as disclosed by cryoreduction electron paramagnetic resonance/electron nuclear double resonance spectroscopy Biochemistry. 44: 1309-1315. PMID 15667224 DOI: 10.1021/Bi048599T |
0.306 |
|
| 2005 |
Mayer KM, Shanklin J. A structural model of the plant acyl-acyl carrier protein thioesterase FatB comprises two helix/4-stranded sheet domains, the N-terminal domain containing residues that affect specificity and the C-terminal domain containing catalytic residues. The Journal of Biological Chemistry. 280: 3621-7. PMID 15531590 DOI: 10.1074/Jbc.M411351200 |
0.442 |
|
| 2004 |
Heilmann I, Mekhedov S, King B, Browse J, Shanklin J. Identification of the Arabidopsis palmitoyl-monogalactosyldiacylglycerol delta7-desaturase gene FAD5, and effects of plastidial retargeting of Arabidopsis desaturases on the fad5 mutant phenotype. Plant Physiology. 136: 4237-45. PMID 15579662 DOI: 10.1104/Pp.104.052951 |
0.437 |
|
| 2004 |
Reipa V, Shanklin J, Vilker V. Substrate binding and the presence of ferredoxin affect the redox properties of the soluble plant Delta9-18:0-acyl carrier protein desaturase. Chemical Communications (Cambridge, England). 2406-7. PMID 15514788 DOI: 10.1039/B409595B |
0.331 |
|
| 2004 |
Heilmann I, Pidkowich MS, Girke T, Shanklin J. Switching desaturase enzyme specificity by alternate subcellular targeting. Proceedings of the National Academy of Sciences of the United States of America. 101: 10266-71. PMID 15240892 DOI: 10.1073/Pnas.0402200101 |
0.413 |
|
| 2003 |
Shanklin J, Whittle E. Evidence linking the Pseudomonas oleovorans alkane omega-hydroxylase, an integral membrane diiron enzyme, and the fatty acid desaturase family. Febs Letters. 545: 188-92. PMID 12804773 DOI: 10.1016/S0014-5793(03)00529-5 |
0.386 |
|
| 2002 |
Behrouzian B, Savile CK, Dawson B, Buist PH, Shanklin J. Exploring the hydroxylation-dehydrogenation connection: novel catalytic activity of castor stearoyl-ACP Delta(9) desaturase. Journal of the American Chemical Society. 124: 3277-83. PMID 11916411 DOI: 10.1021/Ja012252L |
0.302 |
|
| 2002 |
Broadwater JA, Whittle E, Shanklin J. Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity. The Journal of Biological Chemistry. 277: 15613-20. PMID 11864983 DOI: 10.1074/Jbc.M200231200 |
0.468 |
|
| 2002 |
Behrouzian B, Hodgson D, Savile CK, Dawson B, Buist PH, Shanklin J. Use of19F NMR spectroscopy to probe enzymatic oxidation of fluorine-tagged sulfides Magnetic Resonance in Chemistry. 40: 524-528. DOI: 10.1002/Mrc.1052 |
0.323 |
|
| 2001 |
Kachroo P, Shanklin J, Shah J, Whittle EJ, Klessig DF. A fatty acid desaturase modulates the activation of defense signaling pathways in plants Proceedings of the National Academy of Sciences of the United States of America. 98: 9448-9453. PMID 11481500 DOI: 10.1073/Pnas.151258398 |
0.409 |
|
| 2001 |
Whittle E, Shanklin J. Engineering delta 9-16:0-acyl carrier protein (ACP) desaturase specificity based on combinatorial saturation mutagenesis and logical redesign of the castor delta 9-18:0-ACP desaturase. The Journal of Biological Chemistry. 276: 21500-5. PMID 11294879 DOI: 10.1074/Jbc.M102129200 |
0.419 |
|
| 2001 |
Behrouzian B, Buist PH, Shanklin J. Application of KIE and thia approaches in the mechanistic study of a plant stearoyl-ACP Δ9 desaturase Chemical Communications. 401-402. DOI: 10.1039/B008972I |
0.345 |
|
| 2000 |
Cahoon EB, Shanklin J. Substrate-dependent mutant complementation to select fatty acid desaturase variants for metabolic engineering of plant seed oils. Proceedings of the National Academy of Sciences of the United States of America. 97: 12350-5. PMID 11027301 DOI: 10.1073/Pnas.210276297 |
0.665 |
|
| 2000 |
Shanklin J. Overexpression and purification of the Escherichia coli inner membrane enzyme acyl-acyl carrier protein synthase in an active form. Protein Expression and Purification. 18: 355-360. PMID 10733890 DOI: 10.1006/Prep.2000.1206 |
0.398 |
|
| 2000 |
Shanklin J. Exploring the possibilities presented by protein engineering. Current Opinion in Plant Biology. 3: 243-248. DOI: 10.1016/S1369-5266(00)80072-2 |
0.352 |
|
| 1998 |
Shanklin J, Cahoon EB. DESATURATION AND RELATED MODIFICATIONS OF FATTY ACIDS1. Annual Review of Plant Physiology and Plant Molecular Biology. 49: 611-641. PMID 15012248 DOI: 10.1146/annurev.arplant.49.1.611 |
0.593 |
|
| 1998 |
Broun P, Shanklin J, Whittle E, Somerville C. Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. Science (New York, N.Y.). 282: 1315-7. PMID 9812895 DOI: 10.1126/Science.282.5392.1315 |
0.645 |
|
| 1998 |
Cahoon EB, Shah S, Shanklin J, Browse J. A determinant of substrate specificity predicted from the acyl-acyl carrier protein desaturase of developing cat's claw seed. Plant Physiology. 117: 593-8. PMID 9625712 DOI: 10.1104/Pp.117.2.593 |
0.672 |
|
| 1997 |
Cahoon EB, Coughlan SJ, Shanklin J. Characterization of a structurally and functionally diverged acyl-acyl carrier protein desaturase from milkweed seed. Plant Molecular Biology. 33: 1105-10. PMID 9154992 DOI: 10.1023/A:1005821007291 |
0.661 |
|
| 1997 |
Cahoon EB, Lindqvist Y, Schneider G, Shanklin J. Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position Proceedings of the National Academy of Sciences of the United States of America. 94: 4872-4877. PMID 9144157 DOI: 10.1073/Pnas.94.10.4872 |
0.678 |
|
| 1997 |
Shanklin J, Achim C, Schmidt H, Fox BG, Münck E. Mössbauer studies of alkane omega-hydroxylase: evidence for a diiron cluster in an integral-membrane enzyme. Proceedings of the National Academy of Sciences of the United States of America. 94: 2981-6. PMID 9096332 DOI: 10.1073/Pnas.94.7.2981 |
0.339 |
|
| 1996 |
Schultz DJ, Cahoon EB, Shanklin J, Craig R, Cox-Foster DL, Mumma RO, Medford JI. Expression of a delta 9 14:0-acyl carrier protein fatty acid desaturase gene is necessary for the production of omega 5 anacardic acids found in pest-resistant geranium (Pelargonium xhortorum). Proceedings of the National Academy of Sciences of the United States of America. 93: 8771-5. PMID 8710947 DOI: 10.1073/Pnas.93.16.8771 |
0.654 |
|
| 1996 |
Cahoon EB, Mills LA, Shanklin J. Modification of the fatty acid composition of Escherichia coli by coexpression of a plant acyl-acyl carrier protein desaturase and ferredoxin Journal of Bacteriology. 178: 936-939. PMID 8550538 DOI: 10.1128/Jb.178.3.936-939.1996 |
0.672 |
|
| 1996 |
Lindqvist Y, Huang W, Schneider G, Shanklin J. Crystal structure of delta9 stearoyl-acyl carrier protein desaturase from castor seed and its relationship to other di-iron proteins. The Embo Journal. 15: 4081-4092. DOI: 10.1002/J.1460-2075.1996.Tb00783.X |
0.372 |
|
| 1995 |
Shanklin J, DeWitt ND, Flanagan JM. The stroma of higher plant plastids contain ClpP and ClpC, functional homologs of Escherichia coli ClpP and ClpA: an archetypal two-component ATP-dependent protease. The Plant Cell. 7: 1713-1722. PMID 7580259 DOI: 10.1105/Tpc.7.10.1713 |
0.375 |
|
| 1994 |
Caboon EB, Becker CK, Shanklin J, Ohlrogge JB. cDNAs for isoforms of the Δ9-stearoyl-acyl carrier protein desaturase from Thunbergia alata endosperm Plant Physiology. 106: 807-808. PMID 7991701 DOI: 10.1104/Pp.106.2.807 |
0.566 |
|
| 1994 |
Fawcett T, Simon WJ, Swinhoe R, Shanklin J, Nishida I, Christie WW, Slabas AR. Expression of mRNA and steady-state levels of protein isoforms of enoyl-ACP reductase from Brassica napus. Plant Molecular Biology. 26: 155-163. PMID 7948866 DOI: 10.1007/Bf00039528 |
0.356 |
|
| 1994 |
Shanklin J, Whittle E, Fox BG. Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase. Biochemistry. 33: 12787-94. PMID 7947684 DOI: 10.1021/Bi00209A009 |
0.438 |
|
| 1994 |
Fox BG, Shanklin J, Ai J, Loehr TM, Sanders-Loehr J. Resonance Raman evidence for an Fe-O-Fe center in stearoyl-ACP desaturase. Primary sequence identity with other diiron-oxo proteins. Biochemistry. 33: 12776-86. PMID 7947683 DOI: 10.1021/Bi00209A008 |
0.337 |
|
| 1994 |
Cahoon EB, Cranmer AM, Shanklin J, Ohlrogge JB. delta 6 Hexadecenoic acid is synthesized by the activity of a soluble delta 6 palmitoyl-acyl carrier protein desaturase in Thunbergia alata endosperm. Journal of Biological Chemistry. 269: 27519-27526. DOI: 10.1016/s0021-9258(18)47015-9 |
0.337 |
|
| 1994 |
Patel VK, Shanklin J, Furtek DB. Changes in fatty-acid composition and stearoyl-acyl carrier protein desaturase expression in developing Theobroma cacao L. embryos Planta. 193: 83-88. DOI: 10.1007/Bf00191610 |
0.457 |
|
| 1993 |
Fox BG, Shanklin J, Somerville C, Münck E. Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein. Proceedings of the National Academy of Sciences of the United States of America. 90: 2486-90. PMID 8460163 DOI: 10.1073/Pnas.90.6.2486 |
0.595 |
|
| 1992 |
Schneider G, Lindqvist Y, Shanklin J, Somerville C. Preliminary crystallographic data for stearoyl-acyl carrier protein desaturase from castor seed Journal of Molecular Biology. 225: 561-564. PMID 1593637 DOI: 10.1016/0022-2836(92)90941-C |
0.495 |
|
| 1992 |
Cahoon EB, Shanklin J, Ohlrogge JB. Expression of a coriander desaturase results in petroselinic acid production in transgenic tobacco Proceedings of the National Academy of Sciences of the United States of America. 89: 11184-11188. PMID 1454797 DOI: 10.1073/Pnas.89.23.11184 |
0.732 |
|
| 1991 |
Shanklin J, Mullins C, Somerville C. Sequence of a Complementary DNA from Cucumis sativus L. Encoding the Stearoyl-Acyl-Carrier Protein Desaturase. Plant Physiology. 97: 467-468. PMID 16668411 DOI: 10.1104/Pp.97.1.467 |
0.505 |
|
| 1991 |
Shanklin J, Somerville C. Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs. Proceedings of the National Academy of Sciences of the United States of America. 88: 2510-2514. PMID 2006187 DOI: 10.1073/Pnas.88.6.2510 |
0.65 |
|
| 1989 |
Callis J, Pollmann L, Shanklin J, Wettern M, Vierstra RD. Sequence of a cDNA from Chlamydomonas reinhardii encoding a ubiquitin 52 amino acid extension protein. Nucleic Acids Research. 17: 8377. PMID 2554258 DOI: 10.1093/Nar/17.20.8377 |
0.407 |
|
| 1989 |
Shanklin J, Jabben M, Vierstra RD. Partial purification and peptide mapping of ubiquitin-phytochrome conjugates from oat Biochemistry. 28: 6028-6034. DOI: 10.1021/Bi00440A046 |
0.302 |
|
| 1989 |
Keller JM, Shanklin J, Vierstra RD, Hershey HP. Expression of a functional monocotyledonous phytochrome in transgenic tobacco The Embo Journal. 8: 1005-1012. DOI: 10.1002/J.1460-2075.1989.Tb03467.X |
0.366 |
|
| 1987 |
Shanklin J, Jabben M, Vierstra RD. Red light-induced formation of ubiquitin-phytochrome conjugates: Identification of possible intermediates of phytochrome degradation Proceedings of the National Academy of Sciences of the United States of America. 84: 359-363. DOI: 10.1073/Pnas.84.2.359 |
0.327 |
|
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