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Dorothea Fiedler - Publications

Affiliations: 
Chemistry Princeton University, Princeton, NJ 
Area:
second messengers
Website:
http://www.princeton.edu/chemistry/faculty/profiles/fiedler/
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Furkert D, Hostachy S, Nadler-Holly M, Fiedler D. Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome. Cell Chemical Biology. 27: 1097-1108.e4. PMID 32783964 DOI: 10.1016/J.Chembiol.2020.07.017  0.319
2020 Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB. Control of XPR1-dependent cellular phosphate efflux by InsP is an exemplar for functionally-exclusive inositol pyrophosphate signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 32019887 DOI: 10.1073/Pnas.1908830117  0.341
2019 Puschmann R, Harmel RK, Fiedler D. Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates. Biochemistry. PMID 31461621 DOI: 10.1021/Acs.Biochem.9B00587  0.324
2018 Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, et al. MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. Molecular Cell. 70: 936-948.e7. PMID 29883610 DOI: 10.1016/J.Molcel.2018.05.010  0.316
2016 Wu M, Chong LS, Perlman DH, Resnick AC, Fiedler D. Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791083 DOI: 10.1073/Pnas.1606853113  0.309
2016 Chanduri M, Rai A, Malla AB, Wu M, Fiedler D, Mallik R, Bhandari R. Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. The Biochemical Journal. PMID 27474409 DOI: 10.1042/Bcj20160610  0.301
2016 Brown NW, Marmelstein AM, Fiedler D. Chemical tools for interrogating inositol pyrophosphate structure and function. Chemical Society Reviews. PMID 27462803 DOI: 10.1039/C6Cs00193A  0.303
2016 Hager A, Wu M, Wang H, Brown NW, Shears SB, Veiga N, Fiedler D. Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27460418 DOI: 10.1002/Chem.201601754  0.345
2016 Steidle EA, Chong LS, Wu M, Crooke E, Fiedler D, Resnick AC, Rolfes RJ. A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5). The Journal of Biological Chemistry. 291: 6772-83. PMID 26828065 DOI: 10.1074/Jbc.M116.714907  0.309
2015 Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ. Differential genetic interactions of yeast stress response MAPK pathways. Molecular Systems Biology. 11: 800. PMID 25888283 DOI: 10.15252/Msb.20145606  0.471
2015 Yates LM, Fiedler D. Establishing the stability and reversibility of protein pyrophosphorylation with synthetic peptides. Chembiochem : a European Journal of Chemical Biology. 16: 415-23. PMID 25639821 DOI: 10.1002/Cbic.201402589  0.303
2015 Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ. Differential genetic interactions of yeast stress response MAPK pathways Molecular Systems Biology. 11: 1-13. DOI: 10.15252/msb.20145606  0.378
2014 Wu M, Chong LS, Capolicchio S, Jessen HJ, Resnick AC, Fiedler D. Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues. Angewandte Chemie (International Ed. in English). 53: 7192-7. PMID 24888434 DOI: 10.1002/Anie.201402905  0.305
2013 Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Reports. 5: 1725-36. PMID 24360963 DOI: 10.1016/J.Celrep.2013.11.040  0.726
2013 Wu M, Dul BE, Trevisan AJ, Fiedler D. Synthesis and characterization of non-hydrolysable diphosphoinositol polyphosphate second messengers. Chemical Science (Royal Society of Chemistry : 2010). 4: 405-410. PMID 23378892 DOI: 10.1039/C2Sc21553E  0.327
2011 Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K. Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Research. 71: 106-15. PMID 21199799 DOI: 10.1158/0008-5472.Can-10-2732  0.696
2010 van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, et al. Functional overlap and regulatory links shape genetic interactions between signaling pathways. Cell. 143: 991-1004. PMID 21145464 DOI: 10.1016/J.Cell.2010.11.021  0.307
2010 Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, et al. Rewiring of genetic networks in response to DNA damage. Science (New York, N.Y.). 330: 1385-9. PMID 21127252 DOI: 10.1126/Science.1195618  0.472
2010 Mugridge JS, Fiedler D, Raymond KN. A ferrocene-based catecholamide ligand: The consequences of ligand swivel for directed supramolecular self-assembly Journal of Coordination Chemistry. 63: 2779-2789. DOI: 10.1080/00958972.2010.492427  0.729
2009 Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ. Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. Plos Biology. 7: e1000134. PMID 19547744 DOI: 10.1371/Journal.Pbio.1000134  0.503
2009 Okuzumi T, Fiedler D, Zhang C, Gray DC, Aizenstein B, Hoffman R, Shokat KM. Inhibitor hijacking of Akt activation. Nature Chemical Biology. 5: 484-93. PMID 19465931 DOI: 10.1038/Nchembio.183  0.529
2009 Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, et al. Functional organization of the S. cerevisiae phosphorylation network. Cell. 136: 952-63. PMID 19269370 DOI: 10.1016/J.Cell.2008.12.039  0.503
2009 Pluth MD, Fiedler D, Mugridge JS, Bergman RG, Raymond KN. Molecular recognition and self-assembly special feature: Encapsulation and characterization of proton-bound amine homodimers in a water-soluble, self-assembled supramolecular host. Proceedings of the National Academy of Sciences of the United States of America. 106: 10438-43. PMID 19181859 DOI: 10.1073/Pnas.0809806106  0.745
2009 Wang H, Kakaradov B, Collins SR, Karotki L, Fiedler D, Shales M, Shokat KM, Walther TC, Krogan NJ, Koller D. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Molecular & Cellular Proteomics : McP. 8: 1361-81. PMID 19176519 DOI: 10.1074/Mcp.M800490-Mcp200  0.475
2009 Sly LM, Hamilton MJ, Kuroda E, Ho VW, Antignano FL, Omeis SL, van Netten-Thomas CJ, Wong D, Brugger HK, Williams O, Feldman ME, Houseman BT, Fiedler D, Shokat KM, Krystal G. SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood. 113: 2945-54. PMID 19139077 DOI: 10.1182/Blood-2008-06-166082  0.714
2009 Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ. Correction: Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species Plos Biology. 7. DOI: 10.1371/Annotation/66479889-5E57-4213-Bf25-C4E8Cf3D933B  0.438
2008 Wang J, Knight ZA, Fiedler D, Williams O, Shokat KM, Pearce D. Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport. American Journal of Physiology. Renal Physiology. 295: F843-50. PMID 18653476 DOI: 10.1152/Ajprenal.90348.2008  0.724
2008 Hastings CJ, Fiedler D, Bergman RG, Raymond KN. Aza Cope rearrangement of propargyl enammonium cations catalyzed by a self-assembled "nanozyme". Journal of the American Chemical Society. 130: 10977-83. PMID 18652468 DOI: 10.1021/Ja8013055  0.753
2008 Tamgüney T, Zhang C, Fiedler D, Shokat K, Stokoe D. Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells. Experimental Cell Research. 314: 2299-312. PMID 18514190 DOI: 10.1016/J.Yexcr.2008.04.006  0.537
2007 Davis AV, Fiedler D, Ziegler M, Terpin A, Raymond KN. Resolution of chiral, tetrahedral M4L6 metal-ligand hosts. Journal of the American Chemical Society. 129: 15354-63. PMID 18020339 DOI: 10.1021/Ja0764815  0.716
2006 Dong VM, Fiedler D, Carl B, Bergman RG, Raymond KN. Molecular recognition and stabilization of iminium ions in water. Journal of the American Chemical Society. 128: 14464-5. PMID 17090022 DOI: 10.1021/Ja0657915  0.671
2006 Fiedler D, van Halbeek H, Bergman RG, Raymond KN. Supramolecular catalysis of unimolecular rearrangements: substrate scope and mechanistic insights. Journal of the American Chemical Society. 128: 10240-52. PMID 16881654 DOI: 10.1021/Ja062329B  0.58
2006 Andersen UN, Seeber G, Fiedler D, Raymond KN, Lin D, Harris D. Characterization of self-assembled supramolecular [Ga4L6] host-guest complexes by electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 292-6. PMID 16464607 DOI: 10.1016/J.Jasms.2005.10.011  0.513
2006 Davis AV, Fiedler D, Seeber G, Zahl A, van Eldik R, Raymond KN. Guest exchange dynamics in an M4L6 tetrahedral host. Journal of the American Chemical Society. 128: 1324-33. PMID 16433551 DOI: 10.1021/Ja056556+  0.714
2006 Fiedler D, Bergman RG, Raymond KN. Stabilization of reactive organometallic intermediates inside a self-assembled nanoscale host. Angewandte Chemie (International Ed. in English). 45: 745-8. PMID 16370008 DOI: 10.1002/Anie.200501938  0.571
2005 Fiedler D, Leung DH, Bergman RG, Raymond KN. Selective molecular recognition, C-H bond activation, and catalysis in nanoscale reaction vessels. Accounts of Chemical Research. 38: 349-58. PMID 15835881 DOI: 10.1021/Ar040152P  0.693
2004 Fiedler D, Bergman RG, Raymond KN. Supramolecular catalysis of a unimolecular transformation: aza-Cope rearrangement within a self-assembled host. Angewandte Chemie (International Ed. in English). 43: 6748-51. PMID 15558640 DOI: 10.1002/Anie.200461776  0.607
2004 Fiedler D, Leung DH, Bergman RG, Raymond KN. Enantioselective guest binding and dynamic resolution of cationic ruthenium complexes by a chiral metal-ligand assembly. Journal of the American Chemical Society. 126: 3674-5. PMID 15038695 DOI: 10.1021/Ja039225A  0.673
2004 Leung DH, Fiedler D, Bergman RG, Raymond KN. Selective C-H bond activation by a supramolecular host-guest assembly. Angewandte Chemie (International Ed. in English). 43: 963-6. PMID 14966879 DOI: 10.1002/Anie.200352772  0.667
2004 Fiedler D, Pagliero D, Brumaghim JL, Bergman RG, Raymond KN. Encapsulation of cationic ruthenium complexes into a chiral self-assembled cage. Inorganic Chemistry. 43: 846-8. PMID 14753801 DOI: 10.1021/Ic035105S  0.717
2004 Fiedler D, Bergman RG, Raymond KN. Cover Picture: Supramolecular Catalysis of a Unimolecular Transformation: Aza-Cope Rearrangement within a Self-Assembled Host (Angew. Chem. Int. Ed. 48/2004) Angewandte Chemie International Edition. 43: 6565-6565. DOI: 10.1002/Anie.200490169  0.566
2004 Fiedler D, Bergman RG, Raymond KN. Titelbild: Supramolecular Catalysis of a Unimolecular Transformation: Aza-Cope Rearrangement within a Self-Assembled Host (Angew. Chem. 48/2004) Angewandte Chemie. 116: 6727-6727. DOI: 10.1002/Ange.200490164  0.567
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