| Year |
Citation |
Score |
| 2023 |
Sunshine S, Puschnik AS, Replogle JM, Laurie MT, Liu J, Zha BS, Nuñez JK, Byrum JR, McMorrow AH, Frieman MB, Winkler J, Qiu X, Rosenberg OS, Leonetti MD, Ye CJ, ... Weissman JS, et al. Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. Nature Communications. 14: 6245. PMID 37803001 DOI: 10.1038/s41467-023-41788-4 |
0.743 |
|
| 2023 |
Inglis AJ, Guna A, Gálvez-Merchán Á, Pal A, Esantsi TK, Keys HR, Frenkel EM, Oania R, Weissman JS, Voorhees RM. Coupled protein quality control during nonsense-mediated mRNA decay. Journal of Cell Science. 136. PMID 37218462 DOI: 10.1242/jcs.261216 |
0.312 |
|
| 2022 |
Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, ... ... Weissman JS, et al. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. Elife. 11. PMID 36576240 DOI: 10.7554/eLife.81856 |
0.58 |
|
| 2022 |
Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Calvet F, Jungreis I, Gonzalez JM, Magrane M, Martinez TF, Schulz JF, Yang YT, Albà MM, Aspden JL, Baranov PV, Bazzini AA, ... ... Weissman JS, et al. Standardized annotation of translated open reading frames. Nature Biotechnology. PMID 35831657 DOI: 10.1038/s41587-022-01369-0 |
0.556 |
|
| 2022 |
Samelson AJ, Tran QD, Robinot R, Carrau L, Rezelj VV, Kain AM, Chen M, Ramadoss GN, Guo X, Lim SA, Lui I, Nuñez JK, Rockwood SJ, Wang J, Liu N, ... ... Weissman JS, et al. BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nature Cell Biology. 24: 24-34. PMID 35027731 DOI: 10.1038/s41556-021-00821-8 |
0.797 |
|
| 2022 |
Dahan N, Bykov YS, Boydston EA, Fadel A, Gazi Z, Hochberg-Laufer H, Martenson J, Denic V, Shav-Tal Y, Weissman JS, Aviram N, Zalckvar E, Schuldiner M. Peroxisome function relies on organelle-associated mRNA translation. Science Advances. 8: eabk2141. PMID 35020435 DOI: 10.1126/sciadv.abk2141 |
0.775 |
|
| 2021 |
Coukos RW, Yao D, Sanchez ML, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY. An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. Elife. 10. PMID 34414886 DOI: 10.7554/eLife.69142 |
0.337 |
|
| 2021 |
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Elife. 10. PMID 34034859 DOI: 10.7554/eLife.67624 |
0.568 |
|
| 2021 |
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, ... ... Weissman JS, et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. PMID 33838111 DOI: 10.1016/j.cell.2021.03.025 |
0.799 |
|
| 2021 |
Liu K, Santos DA, Hussmann JA, Wang Y, Sutter BM, Weissman JS, Tu BP. Regulation of translation by methylation multiplicity of 18S rRNA. Cell Reports. 34: 108825. PMID 33691096 DOI: 10.1016/j.celrep.2021.108825 |
0.602 |
|
| 2021 |
Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 184: 844. PMID 33545038 DOI: 10.1016/j.cell.2021.01.019 |
0.428 |
|
| 2021 |
Tian R, Samelson AJ, Rezelj VV, Chen M, Ramadoss GN, Guo X, Kain AM, Tran QD, Lim SA, Lui I, Nunez J, Rockwood SJ, Liu N, Carlson-Stevermer J, Oki J, ... ... Weissman JS, et al. BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2. Biorxiv : the Preprint Server For Biology. PMID 33501440 DOI: 10.1101/2021.01.19.427194 |
0.798 |
|
| 2020 |
Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife. 9. PMID 33236988 DOI: 10.7554/eLife.62611 |
0.569 |
|
| 2020 |
Jiménez-Rojo N, Leonetti MD, Zoni V, Colom A, Feng S, Iyengar NR, Matile S, Roux A, Vanni S, Weissman JS, Riezman H. Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway. Current Biology : Cb. PMID 32857977 DOI: 10.1016/J.Cub.2020.07.059 |
0.374 |
|
| 2020 |
Zou K, Rouskin S, Dervishi K, McCormick MA, Sasikumar A, Deng C, Chen Z, Kaeberlein M, Brem RB, Polymenis M, Kennedy BK, Weissman JS, Zheng J, Ouyang Q, Li H. Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span. Science Advances. 6: eaba1306. PMID 32821821 DOI: 10.1126/Sciadv.Aba1306 |
0.777 |
|
| 2020 |
Hickey KL, Dickson K, Cogan JZ, Replogle JM, Schoof M, D'Orazio KN, Sinha NK, Hussmann JA, Jost M, Frost A, Green R, Weissman JS, Kostova KK. GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. Molecular Cell. PMID 32726578 DOI: 10.1016/J.Molcel.2020.07.007 |
0.392 |
|
| 2020 |
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 79: 191-198.e3. PMID 32619469 DOI: 10.1016/J.Molcel.2020.06.008 |
0.601 |
|
| 2020 |
Jones MG, Khodaverdian A, Quinn JJ, Chan MM, Hussmann JA, Wang R, Xu C, Weissman JS, Yosef N. Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Genome Biology. 21: 92. PMID 32290857 DOI: 10.1186/S13059-020-02000-8 |
0.302 |
|
| 2020 |
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, ... Weissman JS, et al. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nature Biotechnology. PMID 32231336 DOI: 10.1038/S41587-020-0470-Y |
0.359 |
|
| 2020 |
Chen J, Brunner AD, Cogan JZ, Nuñez JK, Fields AP, Adamson B, Itzhak DN, Li JY, Mann M, Leonetti MD, Weissman JS. Pervasive functional translation of noncanonical human open reading frames. Science (New York, N.Y.). 367: 1140-1146. PMID 32139545 DOI: 10.1126/Science.Aay0262 |
0.794 |
|
| 2020 |
Jost M, Santos DA, Saunders RA, Horlbeck MA, Hawkins JS, Scaria SM, Norman TM, Hussmann JA, Liem CR, Gross CA, Weissman JS. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. Nature Biotechnology. PMID 31932729 DOI: 10.1038/S41587-019-0387-5 |
0.344 |
|
| 2020 |
Monahan Vargas EJ, Matamoros AJ, Qiu J, Jan CH, Wang Q, Gorczyca D, Han TW, Weissman JS, Jan YN, Banerjee S, Song Y. The microtubule regulator functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes & Development. PMID 31919191 DOI: 10.1101/Gad.331330.119 |
0.3 |
|
| 2020 |
Weissman JS. Abstract IA23: Single cell-resolution lineage tracing of tumors in a mouse xenograft model reveals rapid and multidirectional metastasis Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia23 |
0.305 |
|
| 2019 |
Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. Elife. 8. PMID 31516121 DOI: 10.7554/Elife.48469 |
0.404 |
|
| 2019 |
Bassaganyas L, Popa SJ, Horlbeck M, Puri C, Stewart SE, Campelo F, Ashok A, Butnaru CM, Brouwers N, Heydari K, Ripoche J, Weissman J, Rubinsztein DC, Schekman R, Malhotra V, et al. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. The Journal of Cell Biology. PMID 31488582 DOI: 10.1083/Jcb.201902028 |
0.387 |
|
| 2019 |
Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science (New York, N.Y.). PMID 31395745 DOI: 10.1126/Science.Aax4438 |
0.36 |
|
| 2019 |
McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. Nature Methods. PMID 31209384 DOI: 10.1038/S41592-019-0433-8 |
0.301 |
|
| 2019 |
Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 8. PMID 31149896 DOI: 10.7554/Elife.46595 |
0.644 |
|
| 2019 |
Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 31101715 DOI: 10.1073/Pnas.1904516116 |
0.381 |
|
| 2019 |
Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Molecular recording of mammalian embryogenesis. Nature. PMID 31086336 DOI: 10.1038/S41586-019-1184-5 |
0.315 |
|
| 2019 |
Santos DA, Shi L, Tu BP, Weissman JS. Cycloheximide can distort measurements of mRNA levels and translation efficiency. Nucleic Acids Research. PMID 30916348 DOI: 10.1093/Nar/Gkz205 |
0.657 |
|
| 2019 |
Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD. Cellular response to small molecules that selectively stall protein synthesis by the ribosome. Plos Genetics. 15: e1008057. PMID 30875366 DOI: 10.1371/Journal.Pgen.1008057 |
0.406 |
|
| 2019 |
Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/J.Molcel.2019.01.036 |
0.622 |
|
| 2019 |
Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS. Author response: The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins Elife. DOI: 10.7554/Elife.48469.022 |
0.328 |
|
| 2019 |
Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Author response: Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether Elife. DOI: 10.7554/Elife.46595.022 |
0.581 |
|
| 2018 |
Ingolia NT, Hussmann JA, Weissman JS. Ribosome Profiling: Global Views of Translation. Cold Spring Harbor Perspectives in Biology. PMID 30037969 DOI: 10.1101/Cshperspect.A032698 |
0.695 |
|
| 2018 |
Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Mapping the Genetic Landscape of Human Cells. Cell. PMID 30033366 DOI: 10.1016/J.Cell.2018.06.010 |
0.606 |
|
| 2018 |
Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, ... ... Weissman JS, et al. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. PMID 29995861 DOI: 10.1038/S41586-018-0326-5 |
0.328 |
|
| 2018 |
Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 7. PMID 29985129 DOI: 10.7554/Elife.35388 |
0.392 |
|
| 2018 |
Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers LM, Gestwicki JE. Exploration of Benzothiazole-Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). Journal of Medicinal Chemistry. PMID 29953808 DOI: 10.1021/Acs.Jmedchem.8B00583 |
0.353 |
|
| 2018 |
Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E. The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs. Nature. PMID 29950728 DOI: 10.1038/S41586-018-0258-0 |
0.353 |
|
| 2018 |
Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky J, ... ... Weissman JS, et al. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 7. PMID 29809151 DOI: 10.7554/Elife.37018 |
0.396 |
|
| 2018 |
Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates. Elife. 7. PMID 29745899 DOI: 10.7554/Elife.36620 |
0.6 |
|
| 2018 |
Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... Weissman JS, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/J.Cell.2018.03.068 |
0.314 |
|
| 2018 |
Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Molecular Cell. PMID 29628307 DOI: 10.1016/J.Molcel.2018.02.035 |
0.559 |
|
| 2018 |
Costa EA, Subramanian K, Nunnari J, Weissman JS. Defining the physiological role of SRP in protein-targeting efficiency and specificity. Science (New York, N.Y.). PMID 29348368 DOI: 10.1126/Science.Aar3607 |
0.388 |
|
| 2018 |
Shurtleff MJ, Itzhak DN, Hussmann JA, Oakdale NTS, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, ... ... Weissman JS, et al. Author response: The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins Elife. DOI: 10.7554/Elife.37018.023 |
0.323 |
|
| 2018 |
Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Author response: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates Elife. DOI: 10.7554/Elife.36620.020 |
0.573 |
|
| 2017 |
Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J. Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER. Developmental Cell. PMID 29290583 DOI: 10.1016/J.Devcel.2017.11.023 |
0.307 |
|
| 2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Weissman JS, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041 |
0.527 |
|
| 2017 |
Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Hepatology (Baltimore, Md.). PMID 29091290 DOI: 10.1002/Hep.29626 |
0.334 |
|
| 2017 |
Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK. Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nature Methods. PMID 29083402 DOI: 10.1038/Nmeth.4483 |
0.773 |
|
| 2017 |
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 68: 210-223.e6. PMID 28985505 DOI: 10.1016/J.Molcel.2017.09.012 |
0.6 |
|
| 2017 |
Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science (New York, N.Y.). 357: 414-417. PMID 28751611 DOI: 10.1126/Science.Aam7787 |
0.332 |
|
| 2017 |
Kruth K, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. PMID 28424165 DOI: 10.1182/Blood-2017-02-766204 |
0.604 |
|
| 2017 |
Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 6. PMID 28139975 DOI: 10.7554/Elife.22037 |
0.53 |
|
| 2017 |
Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. Translation from unconventional 5' start sites drives tumour initiation. Nature. PMID 28077873 DOI: 10.1038/Nature21036 |
0.747 |
|
| 2017 |
Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. Model-guided optogenetic study of PKA signaling in budding yeast. Molecular Biology of the Cell. 28: 221-227. PMID 28035051 DOI: 10.1091/Mbc.E16-06-0354 |
0.705 |
|
| 2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Weissman J, et al. Author response: The Human Cell Atlas Elife. DOI: 10.7554/Elife.27041.011 |
0.481 |
|
| 2017 |
Burkhardt DH, Rouskin S, Zhang Y, Li G, Weissman JS, Gross CA. Author response: Operon mRNAs are organized into ORF-centric structures that predict translation efficiency Elife. DOI: 10.7554/Elife.22037.024 |
0.498 |
|
| 2017 |
Weissman J. Abstract IA05: Massively parallel search for synthetic lethal vulnerabilities using CRISPRi and CRISPRa Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Ia05 |
0.396 |
|
| 2017 |
Weissman J. Abstract IA20: Monitoring translation in space and time with ribosome profiling Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-Ia20 |
0.381 |
|
| 2017 |
Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. Abstract 4766: Translation from unconventional 5' start sites drives tumor initiation Cancer Research. 77: 4766-4766. DOI: 10.1158/1538-7445.Am2017-4766 |
0.342 |
|
| 2016 |
Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, ... ... Weissman JS, et al. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 167: 1867-1882.e21. PMID 27984733 DOI: 10.1016/J.Cell.2016.11.048 |
0.795 |
|
| 2016 |
Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, et al. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 167: 1853-1866.e17. PMID 27984732 DOI: 10.1016/J.Cell.2016.11.038 |
0.375 |
|
| 2016 |
Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, ... Weissman JS, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/Science.Aah7111 |
0.365 |
|
| 2016 |
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, ... ... Weissman JS, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/J.Chom.2016.11.001 |
0.556 |
|
| 2016 |
Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature. 540: 134-138. PMID 27905431 DOI: 10.1038/Nature20169 |
0.805 |
|
| 2016 |
Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nature Methods. PMID 27819661 DOI: 10.1038/Nmeth.4057 |
0.324 |
|
| 2016 |
Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. Dynamic translation regulation in Caulobacter cell cycle control. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791168 DOI: 10.1073/Pnas.1614795113 |
0.571 |
|
| 2016 |
Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 5. PMID 27661255 DOI: 10.7554/Elife.19760 |
0.626 |
|
| 2016 |
Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27450084 DOI: 10.1073/Pnas.1603883113 |
0.374 |
|
| 2016 |
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... Weissman JS, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090 |
0.539 |
|
| 2016 |
Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity. Nature Communications. 7: 12009. PMID 27363581 DOI: 10.1038/Ncomms12009 |
0.346 |
|
| 2016 |
Liu YC, Fujimori DG, Weissman JS. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357682 DOI: 10.1073/Pnas.1608795113 |
0.402 |
|
| 2016 |
Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27325776 DOI: 10.1073/Pnas.1600582113 |
0.358 |
|
| 2016 |
Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274053 DOI: 10.1073/Pnas.1606731113 |
0.437 |
|
| 2016 |
Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CH, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, et al. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. PMID 27238023 DOI: 10.1016/J.Cell.2016.05.003 |
0.361 |
|
| 2016 |
Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B. Versatile protein tagging in cells with split fluorescent protein. Nature Communications. 7: 11046. PMID 26988139 DOI: 10.1038/Ncomms11046 |
0.35 |
|
| 2016 |
Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tijan R, Weissman JS. Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife. 5. PMID 26987018 DOI: 10.7554/Elife.12677 |
0.371 |
|
| 2016 |
Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, ... ... Weissman JS, et al. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. PMID 26971820 DOI: 10.1016/J.Stem.2016.01.022 |
0.331 |
|
| 2016 |
Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Author response: Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation Elife. DOI: 10.7554/Elife.19760.031 |
0.58 |
|
| 2016 |
Gilbert LA, Horlbeck MA, Villalta J, Hao S, Gestwicki JE, Weissman JS. Abstract IA27: Retooling CRISPR to turn genes on and off Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-Ia27 |
0.417 |
|
| 2015 |
Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Molecular Cell. 60: 816-27. PMID 26638175 DOI: 10.1016/J.Molcel.2015.11.013 |
0.824 |
|
| 2015 |
Suzuki G, Weissman JS, Tanaka M. [KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis. Molecular Cell. 60: 651-60. PMID 26590718 DOI: 10.1016/J.Molcel.2015.10.020 |
0.332 |
|
| 2015 |
Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, ... ... Weissman JS, et al. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 28: 653-65. PMID 26555175 DOI: 10.1016/J.Ccell.2015.10.002 |
0.644 |
|
| 2015 |
Brar GA, Weissman JS. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nature Reviews. Molecular Cell Biology. 16: 651-64. PMID 26465719 DOI: 10.1038/Nrm4069 |
0.431 |
|
| 2015 |
Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 4. PMID 26327694 DOI: 10.7554/Elife.08153 |
0.557 |
|
| 2015 |
Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. Regulation of mRNA translation during mitosis. Elife. 4. PMID 26305499 DOI: 10.7554/Elife.07957 |
0.404 |
|
| 2015 |
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Next-generation libraries for robust RNA interference-based genome-wide screens. Proceedings of the National Academy of Sciences of the United States of America. 112: E3384-91. PMID 26080438 DOI: 10.1073/Pnas.1508821112 |
0.618 |
|
| 2015 |
Jan CH, Williams CC, Weissman JS. LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science (New York, N.Y.). 348: 1217. PMID 26068842 DOI: 10.1126/Science.Aaa8299 |
0.36 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/Elife.07314 |
0.615 |
|
| 2015 |
Kampmann M, Bassik MC, Weissman JS. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 10: 643. PMID 25811902 DOI: 10.1038/Nprot0415-644D |
0.587 |
|
| 2015 |
Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, ... ... Weissman JS, et al. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science (New York, N.Y.). 348: 36-8. PMID 25791083 DOI: 10.1126/Science.Aab1028 |
0.483 |
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| 2015 |
Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, ... ... Weissman JS, et al. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science (New York, N.Y.). 347: 1259038. PMID 25745177 DOI: 10.1126/Science.1259038 |
0.77 |
|
| 2015 |
Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Validation of the hsp70-bag3 protein-protein interaction as a potential therapeutic target in cancer. Molecular Cancer Therapeutics. 14: 642-8. PMID 25564440 DOI: 10.1158/1535-7163.Mct-14-0650 |
0.632 |
|
| 2015 |
Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science (New York, N.Y.). 347: 75-8. PMID 25554787 DOI: 10.1126/Science.1259724 |
0.368 |
|
| 2015 |
Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 160: 339-50. PMID 25533786 DOI: 10.1016/J.Cell.2014.11.052 |
0.362 |
|
| 2015 |
Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Author response: Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits Elife. DOI: 10.7554/Elife.08153.019 |
0.559 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Author response: Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response Elife. DOI: 10.7554/Elife.07314.017 |
0.555 |
|
| 2015 |
Acosta-Alvear D, Kampmann M, Cho MY, Wild T, Choudhary C, Shuman MA, Weissman JS, Walter P. Abstract A43: Opposing roles of the 19S regulatory- and 20S core-proteasomal subunits in controlling sensitivity of multiple myeloma cells to proteasome inhibition. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A43 |
0.637 |
|
| 2015 |
Gilbert LA, Tanenbaum ME, Horlbeck MA, Adamson B, Villalta JE, Vale RD, Kampmann M, Weissman JS. Abstract PR05: Using genome-scale CRISPR-mediated loss-of-function and gain-of-function screens to analyze gene-drug interactions in cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr05 |
0.628 |
|
| 2015 |
Acosta-Alvear D, Kampmann M, Cho MY, Aftab BT, Li X, Gestwicki JE, Shuman MA, Weissman JS, Walter P. Abstract A2-57: Identification of genetic vulnerabilities within the proteostasis network of multiple myeloma Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-57 |
0.638 |
|
| 2015 |
Kampmann M, Acosta-Alvear D, Gilbert LA, Horlbeck MA, Cho MY, Adamson B, Villalta J, Chen Y, Walter P, Weissman JS. Abstract A2-56: Cancer-specific synthetic lethality and network rewiring elucidated by genetic interaction maps and CRISPR-based gain- and loss-of-function screens Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-56 |
0.642 |
|
| 2015 |
Cho MY, Acosta-Alvear D, Kampmann M, Wild T, Choudhary CR, Weissman JS, Walter P. Abstract A2-12: Opposing roles of the 19S regulatory and 20S core proteasomal subunits in controlling sensitivity to proteasome inhibitors Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-12 |
0.636 |
|
| 2014 |
Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Molecular Systems Biology. 10: 770. PMID 25538139 DOI: 10.15252/Msb.20145524 |
0.797 |
|
| 2014 |
Jan CH, Williams CC, Weissman JS. Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science (New York, N.Y.). 346: 1257521. PMID 25378630 DOI: 10.1126/Science.1257521 |
0.448 |
|
| 2014 |
Williams CC, Jan CH, Weissman JS. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science (New York, N.Y.). 346: 748-51. PMID 25378625 DOI: 10.1126/Science.1257522 |
0.366 |
|
| 2014 |
Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. The general mode of translation inhibition by macrolide antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 111: 15958-63. PMID 25349425 DOI: 10.1073/Pnas.1417334111 |
0.365 |
|
| 2014 |
Albert FW, Muzzey D, Weissman JS, Kruglyak L. Genetic influences on translation in yeast. Plos Genetics. 10: e1004692. PMID 25340754 DOI: 10.1371/Journal.Pgen.1004692 |
0.374 |
|
| 2014 |
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 159: 635-46. PMID 25307933 DOI: 10.1016/J.Cell.2014.09.039 |
0.414 |
|
| 2014 |
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 159: 647-61. PMID 25307932 DOI: 10.1016/J.Cell.2014.09.029 |
0.644 |
|
| 2014 |
Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/Nchembio.1639 |
0.594 |
|
| 2014 |
Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Reports. 8: 1365-79. PMID 25159147 DOI: 10.1016/J.Celrep.2014.07.045 |
0.659 |
|
| 2014 |
Smith MH, Rodriguez EH, Weissman JS. Misfolded proteins induce aggregation of the lectin Yos9. The Journal of Biological Chemistry. 289: 25670-7. PMID 25086047 DOI: 10.1074/Jbc.M114.583344 |
0.808 |
|
| 2014 |
Schrader JM, Zhou B, Li GW, Lasker K, Childers WS, Williams B, Long T, Crosson S, McAdams HH, Weissman JS, Shapiro L. The coding and noncoding architecture of the Caulobacter crescentus genome. Plos Genetics. 10: e1004463. PMID 25078267 DOI: 10.1371/Journal.Pgen.1004463 |
0.577 |
|
| 2014 |
Kampmann M, Bassik MC, Weissman JS. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 9: 1825-47. PMID 24992097 DOI: 10.1038/Nprot.2014.103 |
0.604 |
|
| 2014 |
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications. 5: 3832. PMID 24807418 DOI: 10.1038/Ncomms4832 |
0.6 |
|
| 2014 |
Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/Science.1251871 |
0.34 |
|
| 2014 |
Li GW, Burkhardt D, Gross C, Weissman JS. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 157: 624-35. PMID 24766808 DOI: 10.1016/J.Cell.2014.02.033 |
0.598 |
|
| 2014 |
Muzzey D, Sherlock G, Weissman JS. Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans. Genome Research. 24: 963-73. PMID 24732588 DOI: 10.1101/Gr.166322.113 |
0.338 |
|
| 2014 |
Wolff S, Weissman JS, Dillin A. Differential scales of protein quality control. Cell. 157: 52-64. PMID 24679526 DOI: 10.1016/J.Cell.2014.03.007 |
0.355 |
|
| 2014 |
Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D. KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features. Plos Pathogens. 10: e1003847. PMID 24453964 DOI: 10.1371/Journal.Ppat.1003847 |
0.356 |
|
| 2014 |
Rouskin S, Zubradt M, Washietl S, Kellis M, Weissman JS. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature. 505: 701-5. PMID 24336214 DOI: 10.1038/Nature12894 |
0.791 |
|
| 2014 |
Dunn JG, Foo CK, Belletier NG, Gavis ER, Weissman JS. Correction: Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster Elife. 3. DOI: 10.7554/Elife.03178 |
0.731 |
|
| 2014 |
Foo CK, St. John JA, Westesson O, Hahner NJ, Caulin AF, Skinner ME, Catalano JP, Lung K, Parikh UG, Wellde AS, Barry JK, Wellde GW, Rosell R, Weissman JS, Polkinghorn WR, et al. Clinical validation of a comprehensive cancer genomics analysis for lung cancer patients. Journal of Clinical Oncology. 32: e22122-e22122. DOI: 10.1200/Jco.2014.32.15_Suppl.E22122 |
0.71 |
|
| 2014 |
Giannikopoulos P, John JS, Hahner N, Parker JS, Karachaliou N, Costa C, Westesson O, Parikh U, Foo CK, Cauhlin AF, Lozano MD, Viteri S, Perez-Gracia JL, Curioni A, Jantus-Lewintre E, ... ... Weissman J, et al. Abstract 954: Integrated genomic analysis by whole exome and transcriptome sequencing of tumor samples from EGFR-mutant non-small-cell lung cancer patients with acquired resistance to erlotinib Cancer Research. 74: 954-954. DOI: 10.1158/1538-7445.Am2014-954 |
0.713 |
|
| 2014 |
Foo CK, John JS, Hahner N, Westesson O, Skinner ME, Parikh U, Lung K, Cauhlin AF, Catalano JP, Wellde AS, Barry JK, Wellde GW, Ma P, Rosell R, Zorilla AFC, ... ... Weissman JS, et al. Abstract 4707: Comprehensive integrated genomic analysis Cancer Research. 74: 4707-4707. DOI: 10.1158/1538-7445.Am2014-4707 |
0.72 |
|
| 2014 |
Julien O, Kampmann M, Bassik MC, Venditto VJ, Zorn JA, Rheingold AL, Weissman JS, Wells JA. Unraveling the Mechanism of Cell Death Induced by Chemical and Protein Fibrils Biophysical Journal. 106: 40a. DOI: 10.1016/J.Bpj.2013.11.297 |
0.655 |
|
| 2014 |
Lee M, Schrader J, Li G, Weissman J, McAdams H, Shapiro L, Moerner W. Quantifying the Spatial Organization of Bacterial Ribosomes using Three-Dimensional Super-Resolution Microscopy Biophysical Journal. 106: 492a. DOI: 10.1016/J.Bpj.2013.11.2753 |
0.561 |
|
| 2014 |
Schrader JM, Li G, Zhou B, Weissman JS, Shapiro L. Ribosome Profiling of the Caulobacter Cell-Cycle Biophysical Journal. 106: 375a-376a. DOI: 10.1016/J.Bpj.2013.11.2125 |
0.583 |
|
| 2013 |
Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell. 155: 1479-91. PMID 24360272 DOI: 10.1016/J.Cell.2013.12.001 |
0.537 |
|
| 2013 |
Dunn JG, Foo CK, Belletier NG, Gavis ER, Weissman JS. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Elife. 2: e01179. PMID 24302569 DOI: 10.7554/Elife.01179 |
0.764 |
|
| 2013 |
Stewart-Ornstein J, Nelson C, DeRisi J, Weissman JS, El-Samad H. Msn2 coordinates a stoichiometric gene expression program. Current Biology : Cb. 23: 2336-45. PMID 24210615 DOI: 10.1016/J.Cub.2013.09.043 |
0.728 |
|
| 2013 |
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chemistry & Biology. 20: 1352-63. PMID 24183972 DOI: 10.1016/J.Chembiol.2013.09.014 |
0.697 |
|
| 2013 |
Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Global cellular response to chemotherapy-induced apoptosis. Elife. 2: e01236. PMID 24171104 DOI: 10.7554/Elife.01236 |
0.36 |
|
| 2013 |
Becker AH, Oh E, Weissman JS, Kramer G, Bukau B. Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes. Nature Protocols. 8: 2212-39. PMID 24136347 DOI: 10.1038/Nprot.2013.133 |
0.331 |
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| 2013 |
Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nature Protocols. 8: 2180-96. PMID 24136345 DOI: 10.1038/Nprot.2013.132 |
0.389 |
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| 2013 |
Berchowitz LE, Gajadhar AS, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White FM, Amon A. A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes & Development. 27: 2147-63. PMID 24115771 DOI: 10.1101/Gad.224253.113 |
0.347 |
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| 2013 |
Muzzey D, Schwartz K, Weissman JS, Sherlock G. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biology. 14: R97. PMID 24025428 DOI: 10.1186/Gb-2013-14-9-R97 |
0.316 |
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| 2013 |
Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell. 154: 442-51. PMID 23849981 DOI: 10.1016/J.Cell.2013.06.044 |
0.565 |
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| 2013 |
Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. Genome-wide annotation and quantitation of translation by ribosome profiling. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.18. PMID 23821443 DOI: 10.1002/0471142727.Mb0418S103 |
0.805 |
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| 2013 |
Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell. 154: 240-51. PMID 23810193 DOI: 10.1016/J.Cell.2013.06.009 |
0.661 |
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| 2013 |
Kampmann M, Bassik MC, Weissman JS. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E2317-26. PMID 23739767 DOI: 10.1073/Pnas.1307002110 |
0.63 |
|
| 2013 |
O'Connor PB, Li GW, Weissman JS, Atkins JF, Baranov PV. rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments. Bioinformatics (Oxford, England). 29: 1488-91. PMID 23603333 DOI: 10.1093/Bioinformatics/Btt184 |
0.536 |
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| 2013 |
Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Molecular Biology of the Cell. 24: 1274-89. PMID 23468524 DOI: 10.1091/Mbc.E12-07-0520 |
0.595 |
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| 2013 |
Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 152: 1173-83. PMID 23452860 DOI: 10.1016/J.Cell.2013.02.022 |
0.534 |
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| 2013 |
Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/J.Cell.2013.01.030 |
0.723 |
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| 2013 |
Schuldiner M, Weissman JS. The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. Cold Spring Harbor Perspectives in Biology. 5: a013284. PMID 23359093 DOI: 10.1101/Cshperspect.A013284 |
0.628 |
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| 2013 |
Wei MC, Matheny CJ, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley D, Rau RE, Brown P, McManus MT, Weissman JS, Cleary ML. Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens Blood. 122: 171-171. DOI: 10.1182/Blood.V122.21.171.171 |
0.716 |
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| 2013 |
Kampmann M, Acosta-Alvear D, Cho M, Chen Y, Li X, Gilbert L, Aftab BT, Gestwicki J, Walter P, Weissman JS. Abstract PR07: Systematic genetic interaction maps reveal rewiring of the stress response network and resulting vulnerabilities in leukemia and multiple myeloma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Pr07 |
0.637 |
|
| 2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Cho MY, Aftab BT, Li X, Gestwicki JE, Shuman MA, Weissman JS, Walter P. Abstract C01: Systematic blueprinting of genetic vulnerabilities using ultra-complex shRNA libraries identifies genes synergizing with proteasome inhibition or blockade of IRE1 in multiple myeloma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C01 |
0.652 |
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| 2013 |
Kampmann M, Acosta-Alvear D, Bassik MC, Chen Y, Walter P, Weissman JS. Abstract PR06: Systematic genetic interaction maps reveal synthetic-lethal vulnerabilities in leukemia and multiple myeloma Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Pr06 |
0.636 |
|
| 2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Shuman MA, Weissman JS, Walter P. Abstract A08: Systematic identification of genetic vulnerabilities synergizing with proteasome and IRE1 inhibition in multiple myeloma cells using ultra-complex shRNA libraries Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A08 |
0.643 |
|
| 2013 |
Weissman J. Monitoring Protein Synthesis One Codon at a Time through Ribosome Profiling Biophysical Journal. 104: 377a. DOI: 10.1016/J.Bpj.2012.11.2099 |
0.384 |
|
| 2012 |
Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. Decoding human cytomegalovirus. Science (New York, N.Y.). 338: 1088-93. PMID 23180859 DOI: 10.1126/Science.1227919 |
0.66 |
|
| 2012 |
Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, Li GW, Zhou S, King D, Shen PS, Weibezahn J, Dunn JG, Rouskin S, Inada T, Frost A, Weissman JS. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell. 151: 1042-54. PMID 23178123 DOI: 10.1016/J.Cell.2012.10.044 |
0.794 |
|
| 2012 |
Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nature Protocols. 7: 1534-50. PMID 22836135 DOI: 10.1038/Nprot.2012.086 |
0.802 |
|
| 2012 |
Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, et al. Proto-genes and de novo gene birth. Nature. 487: 370-4. PMID 22722833 DOI: 10.1038/Nature11184 |
0.353 |
|
| 2012 |
Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 149: 1339-52. PMID 22682253 DOI: 10.1016/J.Cell.2012.04.028 |
0.571 |
|
| 2012 |
Churchman LS, Weissman JS. Native elongating transcript sequencing (NET-seq). Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.14.1-17. PMID 22470065 DOI: 10.1002/0471142727.Mb0414S98 |
0.67 |
|
| 2012 |
Li GW, Oh E, Weissman JS. The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria. Nature. 484: 538-41. PMID 22456704 DOI: 10.1038/Nature10965 |
0.578 |
|
| 2012 |
Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, ... Weissman JS, et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 485: 55-61. PMID 22367541 DOI: 10.1038/Nature10912 |
0.621 |
|
| 2012 |
Stewart-Ornstein J, Weissman JS, El-Samad H. Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae. Molecular Cell. 45: 483-93. PMID 22365828 DOI: 10.1016/J.Molcel.2011.11.035 |
0.716 |
|
| 2012 |
Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science (New York, N.Y.). 335: 552-7. PMID 22194413 DOI: 10.1126/Science.1215110 |
0.669 |
|
| 2012 |
Churchman LS, Weissman JS. Visualizing Transcription In Vivo at Nucleotide Resolution using Nascent Transcript Sequencing Biophysical Journal. 102: 611a. DOI: 10.1016/J.Bpj.2011.11.3330 |
0.673 |
|
| 2011 |
Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B. Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo. Cell. 147: 1295-308. PMID 22153074 DOI: 10.1016/J.Cell.2011.10.044 |
0.391 |
|
| 2011 |
Smith MH, Ploegh HL, Weissman JS. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science (New York, N.Y.). 334: 1086-90. PMID 22116878 DOI: 10.1126/Science.1209235 |
0.627 |
|
| 2011 |
Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 108: 19222-7. PMID 22080611 DOI: 10.1073/Pnas.1116948108 |
0.777 |
|
| 2011 |
Ingolia NT, Lareau LF, Weissman JS. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell. 147: 789-802. PMID 22056041 DOI: 10.1016/J.Cell.2011.10.002 |
0.675 |
|
| 2011 |
Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. The Journal of Cell Biology. 195: 323-40. PMID 21987634 DOI: 10.1083/Jcb.201107053 |
0.66 |
|
| 2011 |
Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 476: 88-91. PMID 21814281 DOI: 10.1038/Nature10245 |
0.591 |
|
| 2011 |
Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Molecular and Cellular Biology. 31: 3569-83. PMID 21709022 DOI: 10.1128/Mcb.05590-11 |
0.663 |
|
| 2011 |
Toyama BH, Weissman JS. Amyloid structure: conformational diversity and consequences. Annual Review of Biochemistry. 80: 557-85. PMID 21456964 DOI: 10.1146/Annurev-Biochem-090908-120656 |
0.785 |
|
| 2011 |
Verges KJ, Smith MH, Toyama BH, Weissman JS. Strain conformation, primary structure and the propagation of the yeast prion [PSI+]. Nature Structural & Molecular Biology. 18: 493-9. PMID 21423194 DOI: 10.1038/Nsmb.2030 |
0.789 |
|
| 2011 |
Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, Weissman JS. Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion. Journal of Molecular Biology. 408: 1-8. PMID 21333653 DOI: 10.1016/J.Jmb.2011.02.025 |
0.715 |
|
| 2011 |
Churchman LS, Weissman JS. Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature. 469: 368-73. PMID 21248844 DOI: 10.1038/Nature09652 |
0.669 |
|
| 2011 |
Henry TC, Power JE, Kerwin CL, Mohammed A, Weissman JS, Cameron DM, Wykoff DD. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Eukaryotic Cell. 10: 198-206. PMID 21169418 DOI: 10.1128/Ec.00216-10 |
0.371 |
|
| 2010 |
Weissman JS. The epistemology of cell biology. Molecular Biology of the Cell. 21: 3825. PMID 21079033 DOI: 10.1091/Mbc.E10-04-0370 |
0.395 |
|
| 2010 |
Breslow DK, Weissman JS. Membranes in balance: mechanisms of sphingolipid homeostasis. Molecular Cell. 40: 267-79. PMID 20965421 DOI: 10.1016/J.Molcel.2010.10.005 |
0.761 |
|
| 2010 |
Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 466: 835-40. PMID 20703300 DOI: 10.1038/Nature09267 |
0.633 |
|
| 2010 |
Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. Automated identification of pathways from quantitative genetic interaction data. Molecular Systems Biology. 6: 379. PMID 20531408 DOI: 10.1038/Msb.2010.27 |
0.375 |
|
| 2010 |
Springer M, Weissman JS, Kirschner MW. A general lack of compensation for gene dosage in yeast. Molecular Systems Biology. 6: 368. PMID 20461075 DOI: 10.1038/Msb.2010.19 |
0.377 |
|
| 2010 |
Vembar SS, Jonikas MC, Hendershot LM, Weissman JS, Brodsky JL. J domain co-chaperone specificity defines the role of BiP during protein translocation. The Journal of Biological Chemistry. 285: 22484-94. PMID 20430885 DOI: 10.1074/Jbc.M110.102186 |
0.319 |
|
| 2010 |
Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature. 464: 1006-11. PMID 20228791 DOI: 10.1038/Nature08943 |
0.578 |
|
| 2010 |
Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. Orm family proteins mediate sphingolipid homeostasis. Nature. 463: 1048-53. PMID 20182505 DOI: 10.1038/Nature08787 |
0.815 |
|
| 2010 |
Ohhashi Y, Ito K, Toyama BH, Weissman JS, Tanaka M. Differences in prion strain conformations result from non-native interactions in a nucleus. Nature Chemical Biology. 6: 225-230. PMID 20081853 DOI: 10.1038/Nchembio.306 |
0.793 |
|
| 2009 |
Collins SR, Weissman JS, Krogan NJ. From information to knowledge: new technologies for defining gene function. Nature Methods. 6: 721-23. PMID 19953683 DOI: 10.1038/Nmeth1009-721 |
0.52 |
|
| 2009 |
Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. The Journal of Cell Biology. 186: 323-31. PMID 19651891 DOI: 10.1083/Jcb.200903014 |
0.404 |
|
| 2009 |
Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science (New York, N.Y.). 325: 477-81. PMID 19556461 DOI: 10.1126/Science.1175088 |
0.701 |
|
| 2009 |
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/Nmeth.1330 |
0.79 |
|
| 2009 |
Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. Analysis of Dom34 and its function in no-go decay. Molecular Biology of the Cell. 20: 3025-32. PMID 19420139 DOI: 10.1091/Mbc.E09-01-0028 |
0.356 |
|
| 2009 |
Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science (New York, N.Y.). 323: 1693-7. PMID 19325107 DOI: 10.1126/Science.1167983 |
0.828 |
|
| 2009 |
Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, et al. Functional organization of the S. cerevisiae phosphorylation network. Cell. 136: 952-63. PMID 19269370 DOI: 10.1016/J.Cell.2008.12.039 |
0.551 |
|
| 2009 |
Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (New York, N.Y.). 324: 218-23. PMID 19213877 DOI: 10.1126/Science.1168978 |
0.764 |
|
| 2008 |
Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. High-throughput, quantitative analyses of genetic interactions in E. coli. Nature Methods. 5: 781-7. PMID 19160513 DOI: 10.1038/Nmeth.1240 |
0.533 |
|
| 2008 |
Quan EM, Kamiya Y, Kamiya D, Denic V, Weibezahn J, Kato K, Weissman JS. Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Molecular Cell. 32: 870-7. PMID 19111666 DOI: 10.1016/J.Molcel.2008.11.017 |
0.733 |
|
| 2008 |
Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Molecular Cell. 32: 735-46. PMID 19061648 DOI: 10.1016/J.Molcel.2008.11.012 |
0.554 |
|
| 2008 |
Tipton KA, Verges KJ, Weissman JS. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. Molecular Cell. 32: 584-91. PMID 19026788 DOI: 10.1016/J.Molcel.2008.11.003 |
0.782 |
|
| 2008 |
Chechik G, Oh E, Rando O, Weissman J, Regev A, Koller D. Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Nature Biotechnology. 26: 1251-9. PMID 18953355 DOI: 10.1038/Nbt.1499 |
0.319 |
|
| 2008 |
Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, et al. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science (New York, N.Y.). 322: 405-10. PMID 18818364 DOI: 10.1126/Science.1162609 |
0.557 |
|
| 2008 |
Ingolia NT, Weissman JS. Systems biology: Reverse engineering the cell. Nature. 454: 1059-62. PMID 18756243 DOI: 10.1038/4541059A |
0.587 |
|
| 2008 |
Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell. 134: 634-45. PMID 18724936 DOI: 10.1016/J.Cell.2008.06.025 |
0.797 |
|
| 2008 |
Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nature Methods. 5: 711-8. PMID 18622397 DOI: 10.1038/Nmeth.1234 |
0.793 |
|
| 2008 |
Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Small-molecule aggregates inhibit amyloid polymerization. Nature Chemical Biology. 4: 197-9. PMID 18223646 DOI: 10.1038/Nchembio.65 |
0.783 |
|
| 2008 |
Osherovich LZ, Weissman JS. Insights into the Nature of Yeast Prions Protein Folding Handbook. 3: 1144-1174. DOI: 10.1002/9783527619498.ch68 |
0.508 |
|
| 2007 |
Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 104: 18079-84. PMID 17989219 DOI: 10.1073/Pnas.0708765104 |
0.594 |
|
| 2007 |
Roguev A, Wiren M, Weissman JS, Krogan NJ. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nature Methods. 4: 861-6. PMID 17893680 DOI: 10.1038/Nmeth1098 |
0.354 |
|
| 2007 |
Toyama BH, Kelly MJ, Gross JD, Weissman JS. The structural basis of yeast prion strain variants. Nature. 449: 233-7. PMID 17767153 DOI: 10.1038/Nature06108 |
0.784 |
|
| 2007 |
Denic V, Weissman JS. A molecular caliper mechanism for determining very long-chain fatty acid length. Cell. 130: 663-77. PMID 17719544 DOI: 10.1016/J.Cell.2007.06.031 |
0.703 |
|
| 2007 |
Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 130: 499-511. PMID 17693258 DOI: 10.1016/J.Cell.2007.06.010 |
0.504 |
|
| 2007 |
Ihmels J, Collins SR, Schuldiner M, Krogan NJ, Weissman JS. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Molecular Systems Biology. 3: 86. PMID 17389874 DOI: 10.1038/Msb4100127 |
0.674 |
|
| 2007 |
Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5836-41. PMID 17389396 DOI: 10.1073/Pnas.0607996104 |
0.556 |
|
| 2007 |
Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Weissman JS, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/Nature05649 |
0.778 |
|
| 2007 |
Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 6: 439-50. PMID 17200106 DOI: 10.1074/Mcp.M600381-Mcp200 |
0.565 |
|
| 2006 |
Newman JR, Weissman JS. Systems biology: many things from one. Nature. 444: 561-2. PMID 17122769 DOI: 10.1038/Nature05407 |
0.311 |
|
| 2006 |
Schuldiner M, Collins SR, Weissman JS, Krogan NJ. Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods (San Diego, Calif.). 40: 344-52. PMID 17101447 DOI: 10.1016/J.Ymeth.2006.07.034 |
0.703 |
|
| 2006 |
Tanaka M, Weissman JS. An efficient protein transformation protocol for introducing prions into yeast. Methods in Enzymology. 412: 185-200. PMID 17046659 DOI: 10.1016/S0076-6879(06)12012-1 |
0.394 |
|
| 2006 |
Denic V, Quan EM, Weissman JS. A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell. 126: 349-59. PMID 16873065 DOI: 10.1016/J.Cell.2006.05.045 |
0.742 |
|
| 2006 |
Collins SR, Schuldiner M, Krogan NJ, Weissman JS. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biology. 7: R63. PMID 16859555 DOI: 10.1186/Gb-2006-7-7-R63 |
0.663 |
|
| 2006 |
Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science (New York, N.Y.). 313: 104-7. PMID 16825573 DOI: 10.1126/Science.1129631 |
0.42 |
|
| 2006 |
Tanaka M, Collins SR, Toyama BH, Weissman JS. The physical basis of how prion conformations determine strain phenotypes. Nature. 442: 585-9. PMID 16810177 DOI: 10.1038/Nature04922 |
0.809 |
|
| 2006 |
Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 441: 840-6. PMID 16699522 DOI: 10.1038/Nature04785 |
0.81 |
|
| 2006 |
Bukau B, Weissman J, Horwich A. Molecular chaperones and protein quality control. Cell. 125: 443-51. PMID 16678092 DOI: 10.1016/J.Cell.2006.04.014 |
0.59 |
|
| 2006 |
Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, PeregrÃn-Alvarez JM, Shales M, Zhang X, Davey M, ... ... Weissman JS, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/Nature04670 |
0.723 |
|
| 2006 |
Kulp MS, Frickel EM, Ellgaard L, Weissman JS. Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. The Journal of Biological Chemistry. 281: 876-84. PMID 16368681 DOI: 10.1074/Jbc.M511764200 |
0.774 |
|
| 2005 |
Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comparative and Functional Genomics. 6: 2-16. PMID 18629296 DOI: 10.1002/Cfg.449 |
0.754 |
|
| 2005 |
Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, et al. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 123: 593-605. PMID 16286008 DOI: 10.1016/J.Cell.2005.10.025 |
0.666 |
|
| 2005 |
Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 123: 507-19. PMID 16269340 DOI: 10.1016/J.Cell.2005.08.031 |
0.799 |
|
| 2005 |
Bhamidipati A, Denic V, Quan EM, Weissman JS. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Molecular Cell. 19: 741-51. PMID 16168370 DOI: 10.1016/J.Molcel.2005.07.027 |
0.732 |
|
| 2005 |
Tanaka M, Chien P, Yonekura K, Weissman JS. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell. 121: 49-62. PMID 15820678 DOI: 10.1016/J.Cell.2005.03.008 |
0.58 |
|
| 2004 |
Weissman JS, O'Shea EK. 2004 Irving Sigal Young Investigator Award. Protein Science : a Publication of the Protein Society. 13: 3333-5. PMID 15557272 DOI: 10.1110/Ps.041134604 |
0.602 |
|
| 2004 |
Collins SR, Douglass A, Vale RD, Weissman JS. Mechanism of prion propagation: amyloid growth occurs by monomer addition. Plos Biology. 2: e321. PMID 15383837 DOI: 10.1371/Journal.Pbio.0020321 |
0.523 |
|
| 2004 |
Chien P, Weissman JS, DePace AH. Emerging principles of conformation-based prion inheritance. Annual Review of Biochemistry. 73: 617-56. PMID 15189155 DOI: 10.1146/Annurev.Biochem.72.121801.161837 |
0.762 |
|
| 2004 |
Osherovich LZ, Cox BS, Tuite MF, Weissman JS. Dissection and design of yeast prions. Plos Biology. 2: E86. PMID 15045026 DOI: 10.1371/Journal.Pbio.0020086 |
0.6 |
|
| 2004 |
Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. Conformational variations in an infectious protein determine prion strain differences. Nature. 428: 323-8. PMID 15029196 DOI: 10.1038/Nature02392 |
0.577 |
|
| 2004 |
Tu BP, Weissman JS. Oxidative protein folding in eukaryotes: mechanisms and consequences. The Journal of Cell Biology. 164: 341-6. PMID 14757749 DOI: 10.1083/Jcb.200311055 |
0.624 |
|
| 2003 |
Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 425: 737-41. PMID 14562106 DOI: 10.1038/Nature02046 |
0.763 |
|
| 2003 |
Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Global analysis of protein localization in budding yeast. Nature. 425: 686-91. PMID 14562095 DOI: 10.1038/Nature02026 |
0.67 |
|
| 2003 |
Chien P, DePace AH, Collins SR, Weissman JS. Generation of prion transmission barriers by mutational control of amyloid conformations. Nature. 424: 948-51. PMID 12931190 DOI: 10.1038/Nature01894 |
0.787 |
|
| 2002 |
Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 111: 1027-39. PMID 12507429 DOI: 10.1016/S0092-8674(02)01198-4 |
0.789 |
|
| 2002 |
Tu BP, Weissman JS. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Molecular Cell. 10: 983-94. PMID 12453408 DOI: 10.1016/S1097-2765(02)00696-2 |
0.66 |
|
| 2002 |
DePace AH, Weissman JS. Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nature Structural Biology. 9: 389-96. PMID 11938354 DOI: 10.1038/Nsb786 |
0.668 |
|
| 2002 |
Osherovich LZ, Weissman JS. The utility of prions. Developmental Cell. 2: 143-51. PMID 11832240 DOI: 10.1016/S1534-5807(02)00118-1 |
0.613 |
|
| 2002 |
Weissman JS, Hood JK. Prion diseases. A rogue protein. Lancet (London, England). S53. PMID 11784602 DOI: 10.1016/S0140-6736(01)07065-9 |
0.364 |
|
| 2001 |
Travers KJ, Patil CK, Weissman JS. Functional genomic approaches to understanding molecular chaperones and stress responses. Advances in Protein Chemistry. 59: 345-90. PMID 11868277 DOI: 10.1016/S0065-3233(01)59011-7 |
0.781 |
|
| 2001 |
Fewell SW, Travers KJ, Weissman JS, Brodsky JL. The action of molecular chaperones in the early secretory pathway. Annual Review of Genetics. 35: 149-91. PMID 11700281 DOI: 10.1146/Annurev.Genet.35.102401.090313 |
0.777 |
|
| 2001 |
Weissman JS. The ins and outs of GroEL-mediated protein folding. Molecular Cell. 8: 730-2. PMID 11684006 DOI: 10.1016/S1097-2765(01)00359-8 |
0.406 |
|
| 2001 |
Osherovich LZ, Weissman JS. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell. 106: 183-94. PMID 11511346 DOI: 10.1016/S0092-8674(01)00440-8 |
0.615 |
|
| 2001 |
Chien P, Weissman JS. Conformational diversity in a yeast prion dictates its seeding specificity. Nature. 410: 223-7. PMID 11242084 DOI: 10.1038/35065632 |
0.563 |
|
| 2000 |
Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science (New York, N.Y.). 290: 1571-4. PMID 11090354 DOI: 10.1126/Science.290.5496.1571 |
0.793 |
|
| 2000 |
Michelitsch MD, Weissman JS. A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions. Proceedings of the National Academy of Sciences of the United States of America. 97: 11910-5. PMID 11050225 DOI: 10.1073/Pnas.97.22.11910 |
0.38 |
|
| 2000 |
Sparrer HE, Santoso A, Szoka FC, Weissman JS. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science (New York, N.Y.). 289: 595-9. PMID 10915616 DOI: 10.1126/Science.289.5479.595 |
0.628 |
|
| 2000 |
Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 101: 249-58. PMID 10847680 DOI: 10.1016/S0092-8674(00)80835-1 |
0.78 |
|
| 2000 |
Santoso A, Chien P, Osherovich LZ, Weissman JS. Molecular basis of a yeast prion species barrier. Cell. 100: 277-88. PMID 10660050 DOI: 10.1016/S0092-8674(00)81565-2 |
0.753 |
|
| 1999 |
Wang JD, Weissman JS. Thinking outside the box: new insights into the mechanism of GroEL-mediated protein folding. Nature Structural Biology. 6: 597-600. PMID 10404205 DOI: 10.1038/10636 |
0.486 |
|
| 1998 |
Wang JD, Michelitsch MD, Weissman JS. GroEL-GroES-mediated protein folding requires an intact central cavity. Proceedings of the National Academy of Sciences of the United States of America. 95: 12163-8. PMID 9770457 DOI: 10.1073/Pnas.95.21.12163 |
0.387 |
|
| 1998 |
Pollard MG, Travers KJ, Weissman JS. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Molecular Cell. 1: 171-82. PMID 9659914 DOI: 10.1016/S1097-2765(00)80018-0 |
0.782 |
|
| 1998 |
DePace AH, Santoso A, Hillner P, Weissman JS. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell. 93: 1241-52. PMID 9657156 DOI: 10.1016/S0092-8674(00)81467-1 |
0.768 |
|
| 1998 |
Horwich AL, Burston SG, Rye HS, Weissman JS, Fenton WA. Construction of single-ring and two-ring hybrid versions of bacterial chaperonin GroEL. Methods in Enzymology. 290: 141-6. PMID 9534157 DOI: 10.1016/S0076-6879(98)90013-1 |
0.752 |
|
| 1997 |
Horwich AL, Weissman JS. Deadly conformations--protein misfolding in prion disease. Cell. 89: 499-510. PMID 9160742 DOI: 10.1016/S0092-8674(00)80232-9 |
0.587 |
|
| 1996 |
Fenton WA, Weissman JS, Horwich AL. Putting a lid on protein folding: structure and function of the co-chaperonin, GroES. Chemistry & Biology. 3: 157-61. PMID 8807841 DOI: 10.1016/S1074-5521(96)90257-4 |
0.604 |
|
| 1996 |
Burston SG, Weissman JS, Farr GW, Fenton WA, Horwich AL. Release of both native and non-native proteins from a cis-only GroEL ternary complex. Nature. 383: 96-9. PMID 8779722 DOI: 10.1038/383096A0 |
0.525 |
|
| 1996 |
Weissman JS, Rye HS, Fenton WA, Beechem JM, Horwich AL. Characterization of the active intermediate of a GroEL-GroES-mediated protein folding reaction. Cell. 84: 481-90. PMID 8608602 DOI: 10.1016/S0092-8674(00)81293-3 |
0.755 |
|
| 1995 |
Weissman JS, Kim PS. A kinetic explanation for the rearrangement pathway of BPTI folding. Nature Structural Biology. 2: 1123-30. PMID 8846225 DOI: 10.1038/Nsb1295-1123 |
0.386 |
|
| 1995 |
Horwich AL, Weissman JS, Fenton WA. Kinesis of polypeptide during GroEL-mediated folding. Cold Spring Harbor Symposia On Quantitative Biology. 60: 435-40. PMID 8824417 DOI: 10.1101/Sqb.1995.060.01.048 |
0.529 |
|
| 1995 |
Weissman JS, Sigler PB, Horwich AL. From the cradle to the grave: ring complexes in the life of a protein. Science (New York, N.Y.). 268: 523-4. PMID 7725096 DOI: 10.1126/Science.7725096 |
0.526 |
|
| 1995 |
Weissman JS, Hohl CM, Kovalenko O, Kashi Y, Chen S, Braig K, Saibil HR, Fenton WA, Horwich AL. Mechanism of GroEL action: productive release of polypeptide from a sequestered position under GroES. Cell. 83: 577-87. PMID 7585961 DOI: 10.1016/0092-8674(95)90098-5 |
0.514 |
|
| 1995 |
Yu MH, Weissman JS, Kim PS. Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. Journal of Molecular Biology. 249: 388-97. PMID 7540212 DOI: 10.1006/Jmbi.1995.0304 |
0.404 |
|
| 1994 |
Weissman JS, Kashi Y, Fenton WA, Horwich AL. GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell. 78: 693-702. PMID 7915201 DOI: 10.1016/0092-8674(94)90533-9 |
0.535 |
|
| 1994 |
Craig EA, Weissman JS, Horwich AL. Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell. Cell. 78: 365-72. PMID 7914834 DOI: 10.1016/0092-8674(94)90416-2 |
0.56 |
|
| 1993 |
Weissman JS, Kim PS. Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase. Nature. 365: 185-8. PMID 7690463 DOI: 10.1038/365185A0 |
0.456 |
|
| 1992 |
Weissman JS, Kim PS. Response. Science (New York, N.Y.). 256: 112-4. PMID 17802598 DOI: 10.1126/science.256.5053.112 |
0.319 |
|
| 1992 |
Weissman JS, Kim PS. The pro region of BPTI facilitates folding. Cell. 71: 841-51. PMID 1384990 DOI: 10.1016/0092-8674(92)90559-U |
0.439 |
|
| 1992 |
Weissman JS, Kim PS. Kinetic role of nonnative species in the folding of bovine pancreatic trypsin inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 89: 9900-4. PMID 1384063 DOI: 10.1073/Pnas.89.20.9900 |
0.466 |
|
| 1991 |
Weissman JS, Kim PS. Reexamination of the folding of BPTI: predominance of native intermediates. Science (New York, N.Y.). 253: 1386-93. PMID 1716783 DOI: 10.1126/Science.1716783 |
0.454 |
|
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