| Year |
Citation |
Score |
| 2019 |
Niso M, Mosier PD, Marottoli R, Ferorelli S, Cassano G, Gasparre G, Leopoldo M, Berardi F, Abate C. High-affinity sigma-1 (σ) receptor ligands based on the σ antagonist PB212. Future Medicinal Chemistry. 11: 2547-2562. PMID 31633399 DOI: 10.4155/Fmc-2019-0042 |
0.382 |
|
| 2018 |
Abdelkhalek AS, Alley GS, Alwassil OI, Khatri S, Mosier PD, Nyce HL, White MM, Schulte MK, Dukat M. "Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally-Constrained Phenylguanidines". Acs Chemical Neuroscience. PMID 30375852 DOI: 10.1021/Acschemneuro.8B00431 |
0.311 |
|
| 2018 |
Etobayeva I, Linden SB, Alem F, Harb L, Rizkalla L, Mosier PD, Johnson AA, Temple L, Hakami RM, Nelson DC. Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40- Specific Endolysins. Viruses. 10. PMID 29883383 DOI: 10.3390/V10050276 |
0.364 |
|
| 2018 |
Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011 |
0.328 |
|
| 2017 |
Chiang MJ, Musayev FN, Kosikova M, Lin Z, Gao Y, Mosier PD, Althufairi B, Ye Z, Zhou Q, Desai UR, Xie H, Safo MK. Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication. Emerging Microbes & Infections. 6: e108. PMID 29209052 DOI: 10.1038/Emi.2017.96 |
0.511 |
|
| 2017 |
Sankarayanarayanan NV, Strebel TR, Boothello RS, Sheerin K, Raghuraman A, Sallas F, Mosier PD, Watermeyer ND, Oscarson S, Desai UR. A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II. Angewandte Chemie (International Ed. in English). PMID 28124818 DOI: 10.1002/Anie.201609541 |
0.734 |
|
| 2016 |
Mosier PD, Chiang MJ, Lin Z, Gao Y, Althufairi B, Zhou Q, Musayev F, Safo MK, Xie H, Desai UR. Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1. Scientific Reports. 6: 32340. PMID 27573445 DOI: 10.1038/Srep32340 |
0.547 |
|
| 2016 |
Sarkar A, Yu W, Desai UR, MacKerell AD, Mosier PD. Estimating glycosaminoglycan-protein interaction affinity: Water dominates the specific antithrombin-heparin interaction. Glycobiology. PMID 27496757 DOI: 10.1093/Glycob/Cww073 |
0.774 |
|
| 2015 |
Joseph PR, Mosier PD, Desai UR, Rajarathnam K. Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions. The Biochemical Journal. 472: 121-33. PMID 26371375 DOI: 10.1042/Bj20150059 |
0.655 |
|
| 2015 |
Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 1701-15. PMID 25783191 DOI: 10.1016/J.Bmc.2015.02.055 |
0.331 |
|
| 2015 |
Sakloth F, Kolanos R, Mosier PD, Bonano JS, Banks ML, Partilla JS, Baumann MH, Negus SS, Glennon RA. Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues. British Journal of Pharmacology. 172: 2210-8. PMID 25522019 DOI: 10.1111/Bph.13043 |
0.305 |
|
| 2015 |
Sankaranarayanan NV, Sarkar A, Desai UR, Mosier PD. Designing "high-affinity, high-specificity" glycosaminoglycan sequences through computerized modeling. Methods in Molecular Biology (Clifton, N.J.). 1229: 289-314. PMID 25325961 DOI: 10.1007/978-1-4939-1714-3_24 |
0.795 |
|
| 2014 |
Safo MK, Musayev FN, Mosier PD, Zhou Q, Xie H, Desai UR. Crystal structures of influenza A virus matrix protein M1: variations on a theme. Plos One. 9: e109510. PMID 25295515 DOI: 10.1371/Journal.Pone.0109510 |
0.528 |
|
| 2014 |
Polepally PR, Huben K, Vardy E, Setola V, Mosier PD, Roth BL, Zjawiony JK. Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor. European Journal of Medicinal Chemistry. 85: 818-29. PMID 25193297 DOI: 10.1055/S-0032-1307601 |
0.45 |
|
| 2014 |
Safo MK, Musayev FN, Mosier PD, Zhou Q, Xie H, Desai UR. Crystal structures of influenza a virus matrix protein M1: Variations on a theme Plos One. 9. DOI: 10.1371/journal.pone.0109510 |
0.456 |
|
| 2013 |
Vardy E, Mosier PD, Frankowski KJ, Wu H, Katritch V, Westkaemper RB, Aubé J, Stevens RC, Roth BL. Chemotype-selective modes of action of κ-opioid receptor agonists. The Journal of Biological Chemistry. 288: 34470-83. PMID 24121503 DOI: 10.1074/Jbc.M113.515668 |
0.433 |
|
| 2013 |
Zaidi SA, Arnatt CK, He H, Selley DE, Mosier PD, Kellogg GE, Zhang Y. Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: Application of the 'message-address' concept in development of mu opioid receptor selective antagonists Bioorganic and Medicinal Chemistry. 21: 6405-6413. PMID 24055076 DOI: 10.1016/J.Bmc.2013.08.042 |
0.334 |
|
| 2013 |
Sidhu PS, Mosier PD, Zhou Q, Desai UR. On scaffold hopping: Challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans Bioorganic and Medicinal Chemistry Letters. 23: 355-359. PMID 23164711 DOI: 10.1016/J.Bmcl.2012.10.079 |
0.765 |
|
| 2013 |
Xie H, Lin Z, Mosier PD, Desai UR, Gao Y. The compensatory G88R change is essential in restoring the normal functions of influenza A/WSN/33 virus matrix protein 1 with a disrupted nuclear localization signal Journal of Virology. 87: 345-353. PMID 23077315 DOI: 10.1128/Jvi.02024-12 |
0.499 |
|
| 2012 |
Mosier PD, Krishnasamy C, Kellogg GE, Desai UR. On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. Plos One. 7: e48632. PMID 23152789 DOI: 10.1371/Journal.Pone.0048632 |
0.769 |
|
| 2012 |
Abdel Aziz MH, Sidhu PS, Liang A, Kim JY, Mosier PD, Zhou Q, Farrell DH, Desai UR. Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition Journal of Medicinal Chemistry. 55: 6888-6897. PMID 22788964 DOI: 10.1021/Jm300670Q |
0.718 |
|
| 2012 |
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, et al. Structure of the human κ-opioid receptor in complex with JDTic. Nature. 485: 327-32. PMID 22437504 DOI: 10.1038/Nature10939 |
0.4 |
|
| 2011 |
Abdel Aziz MH, Mosier PD, Desai UR. Identification of the site of binding of sulfated, low molecular weight lignins on thrombin Biochemical and Biophysical Research Communications. 413: 348-352. PMID 21893043 DOI: 10.1016/J.Bbrc.2011.08.102 |
0.785 |
|
| 2011 |
Abate C, Niso M, Lacivita E, Mosier PD, Toscano A, Perrone R. Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4- tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with added polar functionality and reduced lipophilicity for potential use as positron emission tomography radiotracers Journal of Medicinal Chemistry. 54: 1022-1032. PMID 21229979 DOI: 10.1021/Jm1013133 |
0.307 |
|
| 2010 |
Raghuraman A, Mosier PD, Desai UR. Understanding Dermatan Sulfate-Heparin Cofactor II Interaction through Virtual Library Screening. Acs Medicinal Chemistry Letters. 1: 281-285. PMID 20835364 DOI: 10.1021/Ml100048Y |
0.785 |
|
| 2010 |
McGovern DL, Mosier PD, Roth BL, Westkaemper RB. CoMFA analyses of C-2 position salvinorin A analogs at the kappa-opioid receptor provides insights into epimer selectivity. Journal of Molecular Graphics & Modelling. 28: 612-25. PMID 20083418 DOI: 10.1016/J.Jmgm.2009.12.008 |
0.361 |
|
| 2010 |
Shah JR, Mosier PD, Peddi S, Roth BL, Westkaemper RB. 9-Aminomethyl-9,10-dihydroanthracene (AMDA) analogs as structural probes for steric tolerance in 5-HT2A and H1 receptor binding sites. Bioorganic & Medicinal Chemistry Letters. 20: 935-8. PMID 20045641 DOI: 10.1016/J.Bmcl.2009.12.064 |
0.308 |
|
| 2010 |
Raghuraman A, Mosier PD, Desai UR. Understanding dermatan sulfate-heparin cofactor II interaction through virtual library screening Acs Medicinal Chemistry Letters. 1: 281-285. DOI: 10.1021/ml100048y |
0.738 |
|
| 2009 |
Abate C, Mosier PD, Berardi F, Glennon RA. A structure-affinity and comparative molecular field analysis of sigma-2 (σ2) receptor ligands Central Nervous System Agents in Medicinal Chemistry. 9: 246-257. PMID 20021358 DOI: 10.2174/1871524910909030246 |
0.391 |
|
| 2009 |
Shah JR, Mosier PD, Roth BL, Kellogg GE, Westkaemper RB. Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. Bioorganic & Medicinal Chemistry. 17: 6496-504. PMID 19700330 DOI: 10.1016/J.Bmc.2009.08.016 |
0.317 |
|
| 2009 |
Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, Roth BL. Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. Biochemistry. 48: 6898-908. PMID 19555087 DOI: 10.1021/Bi900605N |
0.455 |
|
| 2009 |
Li G, Mosier PD, Fang X, Zhang Y. Toward the three-dimensional structure and lysophosphatidic acid binding characteristics of the LPA4/p2y9/GPR23 receptor: A homology modeling study Journal of Molecular Graphics and Modelling. 28: 70-79. PMID 19423373 DOI: 10.1016/J.Jmgm.2009.04.004 |
0.357 |
|
| 2008 |
Runyon SP, Mosier PD, Roth BL, Glennon RA, Westkaemper RB. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation. Journal of Medicinal Chemistry. 51: 6808-28. PMID 18847250 DOI: 10.1021/Jm800771X |
0.337 |
|
| 2008 |
Dewkar GK, Peddi S, Mosier PD, Roth BL, Westkaemper RB. Methoxy-substituted 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives exhibit differential binding affinities at the 5-HT(2A) receptor. Bioorganic & Medicinal Chemistry Letters. 18: 5268-71. PMID 18774714 DOI: 10.1016/J.Bmcl.2008.08.059 |
0.34 |
|
| 2008 |
Yan F, Mosier PD, Westkaemper RB, Roth BL. Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors. Biochemistry. 47: 1567-78. PMID 18205395 DOI: 10.1021/Bi701476B |
0.341 |
|
| 2008 |
Dukat M, Mosier PD, Kolanos R, Roth BL, Glennon RA. Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies. Journal of Medicinal Chemistry. 51: 603-11. PMID 18201064 DOI: 10.1021/Jm070910S |
0.319 |
|
| 2007 |
Vortherms TA, Mosier PD, Westkaemper RB, Roth BL. Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. The Journal of Biological Chemistry. 282: 3146-56. PMID 17121830 DOI: 10.1074/Jbc.M609264200 |
0.428 |
|
| 2006 |
Raghuraman A, Mosier PD, Desai UR. Finding a needle in a haystack: Development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s) Journal of Medicinal Chemistry. 49: 3553-3562. PMID 16759098 DOI: 10.1021/Jm060092O |
0.779 |
|
| 2005 |
Yan F, Mosier PD, Westkaemper RB, Stewart J, Zjawiony JK, Vortherms TA, Sheffler DJ, Roth BL. Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors. Biochemistry. 44: 8643-51. PMID 15952771 DOI: 10.1021/Bi050490D |
0.454 |
|
| 2003 |
Mosier PD, Jurs PC, Custer LL, Durham SK, Pearl GM. Predicting the genotoxicity of thiophene derivatives from molecular structure. Chemical Research in Toxicology. 16: 721-32. PMID 12807355 DOI: 10.1021/Tx020104I |
0.515 |
|
| 2002 |
Mosier PD, Jurs PC. QSAR/QSPR studies using probabilistic neural networks and generalized regression neural networks. Journal of Chemical Information and Computer Sciences. 42: 1460-70. PMID 12444744 DOI: 10.1021/Ci020039I |
0.499 |
|
| 2002 |
Schweitzer BA, Loida PJ, CaJacob CA, Chott RC, Collantes EM, Hegde SG, Mosier PD, Profeta S. Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching Bioorganic and Medicinal Chemistry Letters. 12: 1743-1746. PMID 12067551 DOI: 10.1016/S0960-894X(02)00283-4 |
0.325 |
|
| 2002 |
Mosier PD, Counterman AE, Jurs PC, Clemmer DE. Prediction of peptide ion collision cross sections from topological molecular structure and amino acid parameters. Analytical Chemistry. 74: 1360-70. PMID 11922305 DOI: 10.1021/Ac0112059 |
0.529 |
|
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