| Year |
Citation |
Score |
| 2024 |
Liu B, Wu T, Miao BA, Ji F, Liu S, Wang P, Zhao Y, Zhong Y, Sundaram A, Zeng TB, Majcherska-Agrawal M, Keenan RJ, Pan T, He C. snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification. Cell. PMID 39579764 DOI: 10.1016/j.cell.2024.10.046 |
0.764 |
|
| 2024 |
DiGuilio A, Cheng B, Zhong F, Jha R, Wan Y, Anghel A, Hu H, Shishkova E, Ji Z, Coon JJ, Keenan RJ. The prolyl isomerase FKBP11 is a secretory translocon accessory factor. Molecular Biology of the Cell. mbcE24070305. PMID 39259761 DOI: 10.1091/mbc.E24-07-0305 |
0.798 |
|
| 2024 |
Lewis AJO, Zhong F, Keenan RJ, Hegde RS. Structural analysis of the dynamic ribosome-translocon complex. Elife. 13. PMID 38896445 DOI: 10.7554/eLife.95814 |
0.819 |
|
| 2024 |
Hegde RS, Keenan RJ. A unifying model for membrane protein biogenesis. Nature Structural & Molecular Biology. PMID 38811793 DOI: 10.1038/s41594-024-01296-5 |
0.365 |
|
| 2022 |
SmalinskaitÄ— L, Kim MK, Lewis AJO, Keenan RJ, Hegde RS. Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature. PMID 36261528 DOI: 10.1038/s41586-022-05336-2 |
0.38 |
|
| 2022 |
Sundaram A, Yamsek M, Zhong F, Hooda Y, Hegde RS, Keenan RJ. Substrate-driven assembly of a translocon for multipass membrane proteins. Nature. PMID 36261522 DOI: 10.1038/s41586-022-05330-8 |
0.798 |
|
| 2021 |
Hegde RS, Keenan RJ. The mechanisms of integral membrane protein biogenesis. Nature Reviews. Molecular Cell Biology. PMID 34556847 DOI: 10.1038/s41580-021-00413-2 |
0.38 |
|
| 2020 |
McGilvray PT, Anghel SA, Sundaram A, Zhong F, Trnka MJ, Fuller JR, Hu H, Burlingame AL, Keenan RJ. An ER translocon for multi-pass membrane protein biogenesis. Elife. 9. PMID 32820719 DOI: 10.7554/Elife.56889 |
0.761 |
|
| 2020 |
O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS. The architecture of EMC reveals a path for membrane protein insertion. Elife. 9. PMID 32459176 DOI: 10.7554/Elife.57887 |
0.466 |
|
| 2020 |
O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS. Author response: The architecture of EMC reveals a path for membrane protein insertion Elife. DOI: 10.7554/Elife.57887.Sa2 |
0.422 |
|
| 2018 |
Mateja A, Keenan RJ. A structural perspective on tail-anchored protein biogenesis by the GET pathway. Current Opinion in Structural Biology. 51: 195-202. PMID 30173121 DOI: 10.1016/J.Sbi.2018.07.009 |
0.459 |
|
| 2017 |
Anghel SA, McGilvray PT, Hegde RS, Keenan RJ. Identification of Oxa1 Homologs Operating in the Eukaryotic Endoplasmic Reticulum. Cell Reports. 21: 3708-3716. PMID 29281821 DOI: 10.1016/J.Celrep.2017.12.006 |
0.804 |
|
| 2017 |
Zalisko BE, Chan C, Denic V, Rock RS, Keenan RJ. Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer. Cell Reports. 20: 2287-2293. PMID 28877464 DOI: 10.1016/J.Celrep.2017.08.035 |
0.774 |
|
| 2017 |
Wohlever ML, Mateja A, McGilvray PT, Day KJ, Keenan RJ. Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins. Molecular Cell. 67: 194-202.e6. PMID 28712723 DOI: 10.1016/J.Molcel.2017.06.019 |
0.815 |
|
| 2017 |
Srivastava R, Zalisko BE, Keenan RJ, Howell SH. The GET System Inserts the Tail-Anchored Protein, SYP72, into Endoplasmic Reticulum Membranes. Plant Physiology. 173: 1137-1145. PMID 27923985 DOI: 10.1104/Pp.16.00928 |
0.783 |
|
| 2016 |
Itakura E, Zavodszky E, Shao S, Wohlever ML, Keenan RJ, Hegde RS. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Molecular Cell. PMID 27345149 DOI: 10.1016/J.Molcel.2016.05.020 |
0.433 |
|
| 2016 |
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Keenan RJ, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882 |
0.469 |
|
| 2015 |
Dominik PK, Borowska MT, Dalmas O, Kim SS, Perozo E, Keenan RJ, Kossiakoff AA. Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. Structure (London, England : 1993). PMID 26749445 DOI: 10.1016/J.Str.2015.11.014 |
0.636 |
|
| 2015 |
Borowska MT, Dominik PK, Anghel SA, Kossiakoff AA, Keenan RJ. A YidC-like Protein in the Archaeal Plasma Membrane. Structure (London, England : 1993). 23: 1715-24. PMID 26256539 DOI: 10.1016/J.Str.2015.06.025 |
0.791 |
|
| 2015 |
Mateja A, Paduch M, Chang HY, Szydlowska A, Kossiakoff AA, Hegde RS, Keenan RJ. Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science (New York, N.Y.). 347: 1152-5. PMID 25745174 DOI: 10.1126/Science.1261671 |
0.638 |
|
| 2015 |
Bestul AJ, Christensen JR, Grzegorzewska AP, Burke TA, Sees JA, Carroll RT, Sirotkin V, Keenan RJ, Kovar DR. Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12. Molecular Biology of the Cell. 26: 283-93. PMID 25392301 DOI: 10.1091/Mbc.E13-05-0281 |
0.312 |
|
| 2011 |
Hegde RS, Keenan RJ. Tail-anchored membrane protein insertion into the endoplasmic reticulum. Nature Reviews. Molecular Cell Biology. 12: 787-98. PMID 22086371 DOI: 10.1038/Nrm3226 |
0.454 |
|
| 2011 |
Mariappan M, Mateja A, Dobosz M, Bove E, Hegde RS, Keenan RJ. The mechanism of membrane-associated steps in tail-anchored protein insertion. Nature. 477: 61-6. PMID 21866104 DOI: 10.1038/Nature10362 |
0.483 |
|
| 2011 |
Sherrill J, Mariappan M, Dominik P, Hegde RS, Keenan RJ. A conserved archaeal pathway for tail-anchored membrane protein insertion. Traffic (Copenhagen, Denmark). 12: 1119-23. PMID 21658170 DOI: 10.1111/J.1600-0854.2011.01229.X |
0.461 |
|
| 2010 |
Mariappan M, Li X, Stefanovic S, Sharma A, Mateja A, Keenan RJ, Hegde RS. A ribosome-associating factor chaperones tail-anchored membrane proteins. Nature. 466: 1120-4. PMID 20676083 DOI: 10.1038/Nature09296 |
0.475 |
|
| 2010 |
Mateja A, Szlachcic A, Downing M, Dobosz M, Mariappan M, Hegde RS, Keenan RJ. Tail-Anchored Membrane Protein Recognition by Get3 Biophysical Journal. 98: 498a. DOI: 10.1016/J.Bpj.2009.12.2715 |
0.474 |
|
| 2009 |
Mateja A, Szlachcic A, Downing ME, Dobosz M, Mariappan M, Hegde RS, Keenan RJ. The structural basis of tail-anchored membrane protein recognition by Get3. Nature. 461: 361-6. PMID 19675567 DOI: 10.1038/Nature08319 |
0.48 |
|
| 2008 |
Schnitzler CE, Keenan RJ, McCord R, Matysik A, Christianson LM, Haddock SH. Spectral diversity of fluorescent proteins from the anthozoan Corynactis californica. Marine Biotechnology (New York, N.Y.). 10: 328-42. PMID 18330643 DOI: 10.1007/S10126-007-9072-7 |
0.308 |
|
| 2005 |
Yuan L, Kurek I, English J, Keenan R. Laboratory-directed protein evolution. Microbiology and Molecular Biology Reviews : Mmbr. 69: 373-92. PMID 16148303 DOI: 10.1128/Mmbr.69.3.373-392.2005 |
0.367 |
|
| 2005 |
Keenan RJ, Siehl DL, Gorton R, Castle LA. DNA shuffling as a tool for protein crystallization. Proceedings of the National Academy of Sciences of the United States of America. 102: 8887-92. PMID 15951425 DOI: 10.1073/Pnas.0502497102 |
0.341 |
|
| 2001 |
Keenan RJ, Freymann DM, Stroud RM, Walter P. The signal recognition particle. Annual Review of Biochemistry. 70: 755-75. PMID 11395422 DOI: 10.1146/Annurev.Biochem.70.1.755 |
0.779 |
|
| 2000 |
Walter P, Keenan R, Schmitz U. Perspectives: structural biology. SRP--where the RNA and membrane worlds meet. Science (New York, N.Y.). 287: 1212-3. PMID 10712156 DOI: 10.1126/Science.287.5456.1212 |
0.494 |
|
| 1999 |
Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James TL. Structure of the phylogenetically most conserved domain of SRP RNA. Rna (New York, N.Y.). 5: 1419-29. PMID 10580470 DOI: 10.1017/S1355838299991458 |
0.735 |
|
| 1999 |
Freymann DM, Keenan RJ, Stroud RM, Walter P. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nature Structural Biology. 6: 793-801. PMID 10426959 DOI: 10.1038/11572 |
0.75 |
|
| 1998 |
Keenan RJ, Freymann DM, Walter P, Stroud RM. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 94: 181-91. PMID 9695947 DOI: 10.1016/S0092-8674(00)81418-X |
0.741 |
|
| 1997 |
Freymann DM, Keenan RJ, Stroud RM, Walter P. Structure of the conserved GTPase domain of the signal recognition particle. Nature. 385: 361-4. PMID 9002524 DOI: 10.1038/385361A0 |
0.767 |
|
| 1997 |
Rutenber E, Fauman EB, Keenan RJ, Fong S, Furth PS, Montellano PROd, Meng E, Kuntz ID, DeCamp DL, Salto R, Rose JR, Craik CS, Stroud RM. Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design. Journal of Biological Chemistry. 268: 15343-15346. DOI: 10.2210/Pdb2Aid/Pdb |
0.438 |
|
| 1996 |
Schmitz U, Freymann DM, James TL, Keenan RJ, Vinayak R, Walter P. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). Rna (New York, N.Y.). 2: 1213-27. PMID 8972771 |
0.696 |
|
| 1996 |
Zenati M, Pham SM, Keenan RJ, Griffith BP. Extracorporeal membrane oxygenation for lung transplant recipients with primary severe donor lung dysfunction Transplant International. 9: 227-230. PMID 8723191 DOI: 10.1007/Bf00335390 |
0.3 |
|
| 1996 |
Freymann D, Keenan R, Stroud R, Walter P. Progress torwards the crystal structure of Ffh, the bacterial homolog of SRP54 Acta Crystallographica Section a Foundations of Crystallography. 52: C167-C167. DOI: 10.1107/S0108767396092574 |
0.723 |
|
| 1995 |
Glassman LR, Keenan RJ, Fabrizio MC, Sonett JR, Bierman MI, Pham SM, Griffith BP. Extracorporeal membrane oxygenation as an adjunct treatment for primary graft failure in adult lung transplant recipients The Journal of Thoracic and Cardiovascular Surgery. 110: 723-727. PMID 7564439 DOI: 10.1016/S0022-5223(95)70104-4 |
0.346 |
|
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