Eric Alani - Publications

Affiliations: 
Biochemistry, Cellular, and Molecular Biology Cornell University, Ithaca, NY, United States 
Area:
Molecular Biology, Genetics, Cell Biology

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Crickard JB, Alani E. The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease. Genetics. PMID 38657110 DOI: 10.1093/genetics/iyae066  0.365
2023 Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Crickard JB, Alani E. The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease. Biorxiv : the Preprint Server For Biology. PMID 38014100 DOI: 10.1101/2023.11.13.566911  0.358
2023 Gioia M, Payero L, Salim S, Fajish V G, Farnaz AF, Pannafino G, Chen JJ, Ajith VP, Momoh S, Scotland M, Raghavan V, Manhart CM, Shinohara A, Nishant KT, Alani E. Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis. Plos Biology. 21: e3002085. PMID 37079643 DOI: 10.1371/journal.pbio.3002085  0.47
2021 Furman CM, Wang TY, Zhao Q, Yugandhar K, Yu H, Alani E. Handcuffing intrinsically disordered regions in Mlh1-Pms1 disrupts mismatch repair. Nucleic Acids Research. PMID 34390347 DOI: 10.1093/nar/gkab694  0.391
2021 Pannafino G, Alani E. Coordinated and Independent Roles for MLH Subunits in DNA Repair. Cells. 10. PMID 33923939 DOI: 10.3390/cells10040948  0.48
2021 Furman CM, Elbashir R, Pannafino G, Clark NL, Alani E. Experimental exchange of paralogous domains in the MLH family provides evidence of sub-functionalization after gene duplication. G3 (Bethesda, Md.). PMID 33871573 DOI: 10.1093/g3journal/jkab111  0.373
2020 Mackenroth B, Alani E. Collaborations between chromatin and nuclear architecture to optimize DNA repair fidelity. Dna Repair. 97: 103018. PMID 33285474 DOI: 10.1016/j.dnarep.2020.103018  0.309
2020 Argueso JL, Alani E. Hundreds of thousands of cell generations reveal a treasure chest of genome alterations. Proceedings of the National Academy of Sciences of the United States of America. PMID 33199644 DOI: 10.1073/pnas.2021185117  0.649
2020 Furman C, Elbashir R, Alani E. Expanded roles for the MutL family of DNA mismatch repair proteins. Yeast (Chichester, England). PMID 32652606 DOI: 10.1002/Yea.3512  0.508
2019 Chakraborty U, Mackenroth B, Shalloway D, Alani E. Chromatin Modifiers Alter Recombination Between Divergent DNA Sequences. Genetics. PMID 31221666 DOI: 10.1534/Genetics.119.302395  0.529
2019 Toledo M, Sun X, Brieño-Enríquez MA, Raghavan V, Gray S, Pea J, Milano CR, Venkatesh A, Patel L, Borst PL, Alani E, Cohen PE. A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I. Plos Genetics. 15: e1008177. PMID 31170160 DOI: 10.1371/Journal.Pgen.1008177  0.488
2018 Kim Y, Furman CM, Manhart CM, Alani E, Finkelstein IJ. Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex. Nucleic Acids Research. PMID 30541127 DOI: 10.1093/Nar/Gky1244  0.502
2018 Raghavan V, Bui DT, Al-Sweel N, Friedrich A, Schacherer J, Aquadro CF, Alani E. Incompatibilities in Mismatch Repair Genes Contribute to a Wide Range of Mutation Rates in Human Isolates of Baker's Yeast. Genetics. PMID 30348651 DOI: 10.1534/Genetics.118.301550  0.449
2018 Chakraborty U, Dinh TA, Alani E. Genomic Instability Promoted by Overexpression of Mismatch Repair Factors in Yeast: A Model for Understanding Cancer Progression. Genetics. PMID 29654124 DOI: 10.1534/Genetics.118.300923  0.52
2017 Al-Sweel N, Raghavan V, Dutta A, Ajith VP, Di Vietro L, Khondakar N, Manhart CM, Surtees JA, Nishant KT, Alani E. Mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-widede. Plos Genetics. 13: e1006974. PMID 28827832 DOI: 10.1371/Journal.Pgen.1006974  0.552
2017 Manhart CM, Alani E. DNA replication and mismatch repair safeguard against metabolic imbalances. Proceedings of the National Academy of Sciences of the United States of America. 114: 5561-5563. PMID 28533419 DOI: 10.1073/Pnas.1705971114  0.563
2017 Manhart CM, Ni X, White MA, Ortega J, Surtees JA, Alani E. The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans. Plos Biology. 15: e2001164. PMID 28453523 DOI: 10.1371/Journal.Pbio.2001164  0.521
2017 Bui DT, Friedrich A, Al-Sweel N, Liti G, Schacherer J, Aquadro CF, Alani E. Mismatch Repair Incompatibilities in Diverse Yeast Populations. Genetics. PMID 28193730 DOI: 10.1534/Genetics.116.199513  0.421
2016 Chakraborty U, Alani E. Understanding how mismatch repair proteins participate in the repair/anti-recombination decision. Fems Yeast Research. PMID 27573382 DOI: 10.1093/Femsyr/Fow071  0.501
2016 Manhart CM, Alani E. Roles for mismatch repair family proteins in promoting meiotic crossing over. Dna Repair. 38: 84-93. PMID 26686657 DOI: 10.1016/J.Dnarep.2015.11.024  0.483
2015 Chakraborty U, George CM, Lyndaker AM, Alani E. A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiae. Genetics. PMID 26680658 DOI: 10.1534/Genetics.115.184093  0.838
2015 Gallardo IF, Pasupathy P, Brown M, Manhart CM, Neikirk DP, Alani E, Finkelstein IJ. High-Throughput Universal DNA Curtain Arrays for Single-Molecule Fluorescence Imaging. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 10310-7. PMID 26325477 DOI: 10.1021/Acs.Langmuir.5B02416  0.443
2015 Bui DT, Dine E, Anderson JB, Aquadro CF, Alani EE. A Genetic Incompatibility Accelerates Adaptation in Yeast. Plos Genetics. 11: e1005407. PMID 26230253 DOI: 10.1371/Journal.Pgen.1005407  0.838
2014 Rogacheva MV, Manhart CM, Chen C, Guarne A, Surtees J, Alani E. Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease. The Journal of Biological Chemistry. 289: 5664-73. PMID 24403070 DOI: 10.1074/Jbc.M113.534644  0.54
2014 Chen C, Jomaa A, Ortega J, Alani EE. Pch2 is a hexameric ring ATPase that remodels the chromosome axis protein Hop1. Proceedings of the National Academy of Sciences of the United States of America. 111: E44-53. PMID 24367111 DOI: 10.1073/pnas.1310755111  0.428
2013 Sonntag Brown M, Lim E, Chen C, Nishant KT, Alani E. Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast. G3 (Bethesda, Md.). 3: 9-22. PMID 23316435 DOI: 10.1534/G3.112.004622  0.564
2013 Clark NL, Alani E, Aquadro CF. Evolutionary rate covariation in meiotic proteins results from fluctuating evolutionary pressure in yeasts and mammals. Genetics. 193: 529-38. PMID 23183665 DOI: 10.1534/Genetics.112.145979  0.348
2012 Gorman J, Wang F, Redding S, Plys AJ, Fazio T, Wind S, Alani EE, Greene EC. Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. 109: E3074-83. PMID 23012240 DOI: 10.1073/Pnas.1211364109  0.812
2012 Ma X, Rogacheva MV, Nishant KT, Zanders S, Bustamante CD, Alani E. Mutation hot spots in yeast caused by long-range clustering of homopolymeric sequences. Cell Reports. 1: 36-42. PMID 22832106 DOI: 10.1016/J.Celrep.2011.10.003  0.775
2012 Plys AJ, Rogacheva MV, Greene EC, Alani E. The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair. Journal of Molecular Biology. 422: 192-203. PMID 22659005 DOI: 10.1016/J.Jmb.2012.05.030  0.845
2012 George CM, Alani E. Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA. Critical Reviews in Biochemistry and Molecular Biology. 47: 297-313. PMID 22494239 DOI: 10.3109/10409238.2012.675644  0.491
2012 Clark NL, Alani E, Aquadro CF. Evolutionary rate covariation reveals shared functionality and coexpression of genes. Genome Research. 22: 714-20. PMID 22287101 DOI: 10.1101/Gr.132647.111  0.336
2011 George CM, Lyndaker AM, Alani E. The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast. Dna Repair. 10: 1086-94. PMID 21978436 DOI: 10.1016/J.Dnarep.2011.07.007  0.837
2011 Kumar C, Piacente SC, Sibert J, Bukata AR, O'Connor J, Alani E, Surtees JA. Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I. Journal of Molecular Biology. 411: 765-80. PMID 21726567 DOI: 10.1016/J.Jmb.2011.06.030  0.567
2011 Zanders S, Sonntag Brown M, Chen C, Alani E. Pch2 modulates chromatid partner choice during meiotic double-strand break repair in Saccharomyces cerevisiae. Genetics. 188: 511-21. PMID 21515575 DOI: 10.1534/Genetics.111.129031  0.799
2011 Sonntag Brown M, Zanders S, Alani E. Sustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast. Genetics. 188: 21-32. PMID 21339478 DOI: 10.1534/Genetics.110.125575  0.771
2010 Nishant KT, Chen C, Shinohara M, Shinohara A, Alani E. Genetic analysis of baker's yeast Msh4-Msh5 reveals a threshold crossover level for meiotic viability. Plos Genetics. 6. PMID 20865162 DOI: 10.1371/Journal.Pgen.1001083  0.508
2010 Nishant KT, Wei W, Mancera E, Argueso JL, Schlattl A, Delhomme N, Ma X, Bustamante CD, Korbel JO, Gu Z, Steinmetz LM, Alani E. The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis. Plos Genetics. 6: e1001109. PMID 20838597 DOI: 10.1371/Journal.Pgen.1001109  0.745
2010 Zanders S, Ma X, Roychoudhury A, Hernandez RD, Demogines A, Barker B, Gu Z, Bustamante CD, Alani E. Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a Bayesian approach. Genetics. 186: 493-503. PMID 20660644 DOI: 10.1534/Genetics.110.120105  0.822
2010 Gorman J, Plys AJ, Visnapuu ML, Alani E, Greene EC. Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice. Nature Structural & Molecular Biology. 17: 932-8. PMID 20657586 DOI: 10.1038/Nsmb.1858  0.817
2010 Gorman J, Plys A, Visnapuu M, Alani E, Greene E. Visualizing the 1D Diffusion of Eukaryotic DNA Repair Factors Along a Chromatin Lattice Biophysical Journal. 98: 591a. DOI: 10.1016/J.Bpj.2009.12.3214  0.824
2009 Nishant KT, Singh ND, Alani E. Genomic mutation rates: what high-throughput methods can tell us. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 912-20. PMID 19644920 DOI: 10.1002/Bies.200900017  0.421
2009 Zanders S, Alani E. The pch2Delta mutation in baker's yeast alters meiotic crossover levels and confers a defect in crossover interference. Plos Genetics. 5: e1000571. PMID 19629178 DOI: 10.1371/Journal.Pgen.1000571  0.794
2009 Lyndaker AM, Alani E. A tale of tails: insights into the coordination of 3' end processing during homologous recombination. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 315-21. PMID 19260026 DOI: 10.1002/Bies.200800195  0.825
2008 Wanat JJ, Kim KP, Koszul R, Zanders S, Weiner B, Kleckner N, Alani E. Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis. Plos Genetics. 4: e1000188. PMID 18818741 DOI: 10.1371/Journal.Pgen.1000188  0.753
2008 Demogines A, Smith E, Kruglyak L, Alani E. Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. Plos Genetics. 4: e1000123. PMID 18617998 DOI: 10.1371/Journal.Pgen.1000123  0.814
2008 Lyndaker AM, Goldfarb T, Alani E. Mutants defective in Rad1-Rad10-Slx4 exhibit a unique pattern of viability during mating-type switching in Saccharomyces cerevisiae. Genetics. 179: 1807-21. PMID 18579504 DOI: 10.1534/Genetics.108.090654  0.843
2008 Demogines A, Wong A, Aquadro C, Alani E. Incompatibilities involving yeast mismatch repair genes: a role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates. Plos Genetics. 4: e1000103. PMID 18566663 DOI: 10.1371/Journal.Pgen.1000103  0.812
2008 Nishant KT, Plys AJ, Alani E. A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae. Genetics. 179: 747-55. PMID 18505871 DOI: 10.1534/Genetics.108.086645  0.83
2008 Xu X, Page JL, Surtees JA, Liu H, Lagedrost S, Lu Y, Bronson R, Alani E, Nikitin AY, Weiss RS. Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms. Cancer Research. 68: 2652-60. PMID 18413732 DOI: 10.1158/0008-5472.Can-07-5873  0.349
2007 Gorman J, Chowdhury A, Surtees JA, Shimada J, Reichman DR, Alani E, Greene EC. Dynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6. Molecular Cell. 28: 359-70. PMID 17996701 DOI: 10.1016/J.Molcel.2007.09.008  0.517
2007 Wanat JJ, Singh N, Alani E. The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations. Human Molecular Genetics. 16: 445-52. PMID 17210669 DOI: 10.1093/Hmg/Ddl479  0.822
2007 Lee SD, Surtees JA, Alani E. Saccharomyces cerevisiae MSH2-MSH3 and MSH2-MSH6 complexes display distinct requirements for DNA binding domain I in mismatch recognition. Journal of Molecular Biology. 366: 53-66. PMID 17157869 DOI: 10.1016/J.Jmb.2006.10.099  0.556
2006 Heck JA, Gresham D, Botstein D, Alani E. Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements. Genetics. 174: 519-23. PMID 16816424 DOI: 10.1534/Genetics.106.059311  0.845
2006 Surtees JA, Alani E. Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination. Journal of Molecular Biology. 360: 523-36. PMID 16781730 DOI: 10.1016/J.Jmb.2006.05.032  0.494
2006 Heck JA, Argueso JL, Gemici Z, Reeves RG, Bernard A, Aquadro CF, Alani E. Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. 103: 3256-61. PMID 16492773 DOI: 10.1073/Pnas.0510998103  0.831
2006 Lee SD, Alani E. Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA. Journal of Molecular Biology. 355: 175-84. PMID 16303135 DOI: 10.1016/J.Jmb.2005.10.059  0.509
2005 Jiang J, Bai L, Surtees JA, Gemici Z, Wang MD, Alani E. Detection of high-affinity and sliding clamp modes for MSH2-MSH6 by single-molecule unzipping force analysis. Molecular Cell. 20: 771-81. PMID 16337600 DOI: 10.1016/J.Molcel.2005.10.014  0.501
2005 Goldfarb T, Alani E. Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal. Genetics. 169: 563-74. PMID 15489516 DOI: 10.1534/Genetics.104.035204  0.793
2004 Argueso JL, Wanat J, Gemici Z, Alani E. Competing crossover pathways act during meiosis in Saccharomyces cerevisiae Genetics. 168: 1805-1816. PMID 15611158 DOI: 10.1534/Genetics.104.032912  0.801
2004 Surtees JA, Argueso JL, Alani E. Mismatch repair proteins: Key regulators of genetic recombination Cytogenetic and Genome Research. 107: 146-159. PMID 15467360 DOI: 10.1159/000080593  0.788
2004 Surtees JA, Alani E. Replication factors license exonuclease I in mismatch repair. Molecular Cell. 15: 164-6. PMID 15260965 DOI: 10.1016/J.Molcel.2004.07.004  0.382
2004 Sugawara N, Goldfarb T, Studamire B, Alani E, Haber JE. Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1 Proceedings of the National Academy of Sciences of the United States of America. 101: 9315-9320. PMID 15199178 DOI: 10.1073/Pnas.0305749101  0.833
2004 Goldfarb T, Alani E. Chromatin immunoprecipitation to investigate protein-DNA interactions during genetic recombination. Methods in Molecular Biology (Clifton, N.J.). 262: 223-37. PMID 14769965 DOI: 10.1385/1-59259-761-0:223  0.748
2004 Cohen PE, Bhagat R, Manheim EA, Sherizen DE, Alani E, Blanton H, Sekelsky J, Tease C, Hultén MA, Hoffmann ER, Borts RH, Ashley T, Westphal C, Maggio AP, Rooij DGd, et al. Contents Vol. 107, 2004 Cytogenetic and Genome Research. 107: 265-266. DOI: 10.1159/000081422  0.633
2004 Cohen PE, Bhagat R, Manheim EA, Sherizen DE, Alani E, Blanton H, Sekelsky J, Tease C, Hultén MA, Hoffmann ER, Borts RH, Ashley T, Westphal C, Maggio AP, Rooij DGd, et al. Subject Index Vol. 107, 3–4, 2004 Cytogenetic and Genome Research. 107: 264. DOI: 10.1159/000081421  0.636
2003 Wang H, Yang Y, Schofield MJ, Du C, Fridman Y, Lee SD, Larson ED, Drummond JT, Alani E, Hsieh P, Erie DA. DNA bending and unbending by MutS govern mismatch recognition and specificity. Proceedings of the National Academy of Sciences of the United States of America. 100: 14822-7. PMID 14634210 DOI: 10.1073/Pnas.2433654100  0.497
2003 Kijas AW, Studamire B, Alani E. Msh2 separation of function mutations confer defects in the initiation steps of mismatch repair. Journal of Molecular Biology. 331: 123-38. PMID 12875840 DOI: 10.1016/S0022-2836(03)00694-6  0.842
2003 Alani E, Lee JY, Schofield MJ, Kijas AW, Hsieh P, Yang W. Crystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair. The Journal of Biological Chemistry. 278: 16088-94. PMID 12582174 DOI: 10.1074/jbc.M213193200  0.383
2003 Argueso JL, Kijas AW, Sarin S, Heck J, Waase M, Alani E. Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair. Molecular and Cellular Biology. 23: 873-86. PMID 12529393 DOI: 10.1128/Mcb.23.3.873-886.2003  0.848
2002 Argueso JL, Smith D, Yi J, Waase M, Sarin S, Alani E. Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over. Genetics. 160: 909-21. PMID 11901110  0.762
2001 Xie Y, Liu Y, Argueso JL, Henricksen LA, Kao HI, Bambara RA, Alani E. Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage. Molecular and Cellular Biology. 21: 4889-99. PMID 11438646 DOI: 10.1128/Mcb.21.15.4889-4899.2001  0.821
2001 Bowers J, Tran PT, Joshi A, Liskay RM, Alani E. MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp. Journal of Molecular Biology. 306: 957-68. PMID 11237611 DOI: 10.1006/Jmbi.2001.4467  0.756
2000 Evans E, Alani E. Roles for mismatch repair factors in regulating genetic recombination Molecular and Cellular Biology. 20: 7839-7844. PMID 11027255 DOI: 10.1128/Mcb.20.21.7839-7844.2000  0.535
2000 Bowers J, Tran PT, Liskay RM, Alani E. Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps. Journal of Molecular Biology. 302: 327-38. PMID 10970737 DOI: 10.1006/Jmbi.2000.4081  0.767
2000 Evans E, Sugawara N, Haber JE, Alani E. The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo. Molecular Cell. 5: 789-99. PMID 10882115 DOI: 10.1016/S1097-2765(00)80319-6  0.535
2000 Sokolsky T, Alani E. EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae Genetics. 155: 589-599. PMID 10835383  0.457
1999 Studamire B, Price G, Sugawara N, Haber JE, Alani E. Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination. Molecular and Cellular Biology. 19: 7558-67. PMID 10523644 DOI: 10.1128/Mcb.19.11.7558  0.862
1999 Bowers J, Sokolsky T, Quach T, Alani E. A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition. The Journal of Biological Chemistry. 274: 16115-25. PMID 10347163 DOI: 10.1074/Jbc.274.23.16115  0.842
1999 Xie Y, Counter C, Alani E. Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader Genetics. 151: 499-509. PMID 9927446  0.492
1998 Studamire B, Quach T, Alani E. Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair. Molecular and Cellular Biology. 18: 7590-601. PMID 9819445 DOI: 10.1128/Mcb.18.12.7590  0.834
1997 Alani E, Sokolsky T, Studamire B, Miret JJ, Lahue RS. Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Molecular and Cellular Biology. 17: 2436-47. PMID 9111312 DOI: 10.1128/Mcb.17.5.2436  0.814
1997 Alani E, Lee S, Kane MF, Griffith J, Kolodner RD. Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes holliday junctions in DNA Journal of Molecular Biology. 265: 289-301. PMID 9018043 DOI: 10.1006/Jmbi.1996.0743  0.682
1996 Alani E. The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs Molecular and Cellular Biology. 16: 5604-5615. PMID 8816473 DOI: 10.1128/Mcb.16.10.5604  0.501
1995 Alani E, Chi NW, Kolodner R. The saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions Genes and Development. 9: 234-247. PMID 7851796 DOI: 10.1101/Gad.9.2.234  0.675
1994 Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast Science. 265: 1091-1093. PMID 8066446 DOI: 10.1126/Science.8066446  0.708
1994 Alani E, Reenan RA, Kolodner RD. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics. 137: 19-39. PMID 8056309  0.809
1994 Kolodner RD, Alani E. Mismatch repair and cancer susceptibility Current Opinion in Biotechnology. 5: 585-594. PMID 7765740 DOI: 10.1016/0958-1669(94)90079-5  0.655
1992 Alani E, Thresher R, Griffith JD, Kolodner RD. Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein Journal of Molecular Biology. 227: 54-71. PMID 1522601 DOI: 10.1016/0022-2836(92)90681-9  0.641
1990 Cao L, Alani E, Kleckner N. A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae Cell. 61: 1089-1101. PMID 2190690 DOI: 10.1016/0092-8674(90)90072-M  0.698
1990 Alani E, Padmore R, Kleckner N. Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination Cell. 61: 419-436. PMID 2185891 DOI: 10.1016/0092-8674(90)90524-I  0.714
1989 Alani E, Subbiah S, Kleckner N. The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions Genetics. 122: 47-57. PMID 2659437  0.358
1987 Alani E, Cao L, Kleckner N. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains Genetics. 116: 541-545. PMID 3305158 DOI: 10.1534/Genetics.112.541.Test  0.607
1984 Guarente L, Lalonde B, Gifford P, Alani E. Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae Cell. 36: 503-511. PMID 6319028 DOI: 10.1016/0092-8674(84)90243-5  0.328
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