| Year |
Citation |
Score |
| 2022 |
O'Connell P, Blake MK, Godbehere S, Amalfitano A, Aldhamen YA. SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity. Journal of Neuroinflammation. 19: 241. PMID 36199066 DOI: 10.1186/s12974-022-02594-9 |
0.609 |
|
| 2022 |
Blake MK, O'Connell P, Pepelyayeva Y, Godbehere S, Aldhamen YA, Amalfitano A. ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses. Bmc Immunology. 23: 9. PMID 35246034 DOI: 10.1186/s12865-022-00481-9 |
0.651 |
|
| 2021 |
O'Connell P, Blake MK, Pepelyayeva Y, Hyslop S, Godbehere S, Angarita AM, Pereira-Hicks C, Amalfitano A, Aldhamen YA. Adenoviral delivery of an immunomodulatory protein to the tumor microenvironment controls tumor growth. Molecular Therapy Oncolytics. 24: 180-193. PMID 35036523 DOI: 10.1016/j.omto.2021.12.004 |
0.649 |
|
| 2021 |
O'Connell P, Blake MK, Godbehere S, Aldhamen YA, Amalfitano A. Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 34810226 DOI: 10.4049/jimmunol.2100813 |
0.59 |
|
| 2020 |
O'Connell P, Hyslop S, Blake MK, Godbehere S, Amalfitano A, Aldhamen YA. SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment. Journal of Immunology (Baltimore, Md. : 1950). PMID 33288545 DOI: 10.4049/jimmunol.2000300 |
0.592 |
|
| 2020 |
O'Connell P, Aldhamen YA. Systemic innate and adaptive immune responses to SARS-CoV-2 as it relates to other coronaviruses. Human Vaccines & Immunotherapeutics. 1-12. PMID 32878546 DOI: 10.1080/21645515.2020.1802974 |
0.346 |
|
| 2020 |
O'Connell P, Aldhamen YA. Systemic innate and adaptive immune responses to SARS-CoV-2 as it relates to other coronaviruses. Human Vaccines & Immunotherapeutics. 1-12. PMID 32878546 DOI: 10.1080/21645515.2020.1802974 |
0.452 |
|
| 2019 |
O'Connell P, Zheng YH, Amalfitano A, Aldhamen YA. Infection of Primary Human Monocytes with HIV-1. Bio-Protocol. 9. PMID 32002449 DOI: 10.21769/bioprotoc.3289 |
0.538 |
|
| 2019 |
O'Connell P, Amalfitano A, Aldhamen YA. SLAM Family Receptor Signaling in Viral Infections: HIV and Beyond. Vaccines. 7. PMID 31744090 DOI: 10.3390/Vaccines7040184 |
0.662 |
|
| 2018 |
O'Connell P, Pepelyayeva Y, Blake MK, Hyslop S, Crawford RB, Rizzo MD, Pereira-Hicks C, Godbehere S, Dale L, Gulick P, Kaminski NE, Amalfitano A, Aldhamen YA. SLAMF7 Is a Critical Negative Regulator of IFN-α-Mediated CXCL10 Production in Chronic HIV Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 30530590 DOI: 10.4049/Jimmunol.1800847 |
0.674 |
|
| 2018 |
Pepelyayeva Y, Rastall DPW, Aldhamen YA, O'Connell P, Raehtz S, Alyaqoub FS, Blake MK, Raedy AM, Angarita AM, Abbas AM, Pereira-Hicks CN, Roosa SG, McCabe L, Amalfitano A. ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis. Scientific Reports. 8: 12464. PMID 30127455 DOI: 10.1038/S41598-018-30159-5 |
0.583 |
|
| 2017 |
Rizzo MD, Crawford RB, Henriquez JE, Aldhamen Y, Gulick P, Amalfitano A, Kaminski NE. HIV-infected cannabis users have lower circulating CD16+ monocytes and IP-10 levels compared to non-using HIV patients. Aids (London, England). PMID 29194121 DOI: 10.1097/Qad.0000000000001704 |
0.589 |
|
| 2017 |
Rastall DPW, Alyaquob FS, O'Connell P, Pepelyayeva Y, Peters D, Godbehere-Roosa S, Pereira-Hicks C, Aldhamen YA, Amalfitano A. Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality. International Immunology. 29: 277-289. PMID 28814066 DOI: 10.1093/Intimm/Dxx035 |
0.664 |
|
| 2017 |
Quiroga D, Aldhamen YA, Godbehere S, Harding L, Amalfitano A. Decreased vector gene expression from E2b-deleted Ad5 vaccines intensifies pro-inflammatory immune responses. Clinical and Vaccine Immunology : Cvi. PMID 28381403 DOI: 10.1128/Cvi.00061-17 |
0.842 |
|
| 2017 |
Amalfitano A, Alyaqoub FS, Aldhamen YA, Abbas A, Pereira-Hicks C, Godbehere S, Waters CM. Abstract 2994: Engineered STING-targeting immunotherapy delays B16 melanoma tumor growth and significantly improves animal survival as compared to an immune-checkpoint inhibitor Cancer Research. 77: 2994-2994. DOI: 10.1158/1538-7445.Am2017-2994 |
0.611 |
|
| 2016 |
Rastall DP, Seregin SS, Aldhamen YA, Kaiser LM, Mullins C, Liou A, Ing F, Pereria-Hicks C, Godbehere-Roosa S, Palmer D, Ng P, Amalfitano A. Long-term, high level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus. Gene Therapy. PMID 27367841 DOI: 10.1038/Gt.2016.53 |
0.698 |
|
| 2016 |
Aldhamen YA, Rastall DP, Chen W, Seregin SS, Pereira-Hicks C, Godbehere S, Kaminski NE, Amalfitano A. CRACC-targeting Fc-fusion protein induces activation of NK cells and DCs and improves T cell immune responses to antigenic targets. Vaccine. PMID 27151882 DOI: 10.1016/J.Vaccine.2016.04.068 |
0.825 |
|
| 2016 |
Alyaqoub FS, Aldhamen YA, Koestler BJ, Bruger EL, Seregin SS, Pereira-Hicks C, Godbehere S, Waters CM, Amalfitano A. In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 26792800 DOI: 10.4049/Jimmunol.1501272 |
0.833 |
|
| 2016 |
Aldhamen YA, Amalfitano A. Methods to Mitigate Immune Responses to Adenoviral Vectors Adenoviral Vectors For Gene Therapy: Second Edition. 391-422. DOI: 10.1016/B978-0-12-800276-6.00016-4 |
0.676 |
|
| 2015 |
Quiroga D, Aldhamen YA, Appledorn DM, Godbehere S, Amalfitano A. Strengthened tumor antigen immune recognition by inclusion of a recombinant Eimeria antigen in therapeutic cancer vaccination. Cancer Immunology, Immunotherapy : Cii. 64: 479-91. PMID 25655760 DOI: 10.1007/S00262-015-1659-7 |
0.853 |
|
| 2015 |
Aldhamen YA, Pepelyayeva Y, Rastall DP, Seregin SS, Zervoudi E, Koumantou D, Aylsworth CF, Quiroga D, Godbehere S, Georgiadis D, Stratikos E, Amalfitano A. Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells. Journal of Innate Immunity. 7: 275-89. PMID 25591727 DOI: 10.1159/000368899 |
0.833 |
|
| 2014 |
Koestler BJ, Seregin SS, Rastall DP, Aldhamen YA, Godbehere S, Amalfitano A, Waters CM. Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus. Clinical and Vaccine Immunology : Cvi. 21: 1550-9. PMID 25230938 DOI: 10.1128/Cvi.00471-14 |
0.806 |
|
| 2014 |
Rastall DP, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses. International Immunology. 26: 685-95. PMID 25087231 DOI: 10.1093/Intimm/Dxu078 |
0.73 |
|
| 2014 |
Aldhamen YA, Seregin SS, Aylsworth CF, Godbehere S, Amalfitano A. Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. International Immunology. 26: 291-303. PMID 24374770 DOI: 10.1093/Intimm/Dxt061 |
0.826 |
|
| 2013 |
Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, Aldhamen YA, Amalfitano A, Mavridis IM, James E, Georgiadis D, Stratikos E. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 19890-5. PMID 24248368 DOI: 10.1073/Pnas.1309781110 |
0.782 |
|
| 2013 |
Aldhamen YA, Seregin SS, Kousa YA, Rastall DP, Appledorn DM, Godbehere S, Schutte BC, Amalfitano A. Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2. Cancer Gene Therapy. 20: 564-75. PMID 23949283 DOI: 10.1038/Cgt.2013.53 |
0.812 |
|
| 2013 |
Aldhamen YA, Seregin SS, Rastall DP, Aylsworth CF, Pepelyayeva Y, Busuito CJ, Godbehere-Roosa S, Kim S, Amalfitano A. Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response. Plos One. 8: e69539. PMID 23894499 DOI: 10.1371/Journal.Pone.0069539 |
0.779 |
|
| 2013 |
Aylsworth CF, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. Activation of human natural killer cells by the novel innate immune modulator recombinant Eimeria antigen. Human Immunology. 74: 916-26. PMID 23639554 DOI: 10.1016/J.Humimm.2013.04.035 |
0.79 |
|
| 2012 |
Aldhamen YA, Seregin SS, Schuldt NJ, Rastall DP, Liu CJ, Godbehere S, Amalfitano A. Vaccines expressing the innate immune modulator EAT-2 elicit potent effector memory T lymphocyte responses despite pre-existing vaccine immunity. Journal of Immunology (Baltimore, Md. : 1950). 189: 1349-59. PMID 22745373 DOI: 10.4049/Jimmunol.1200736 |
0.846 |
|
| 2012 |
Schuldt NJ, Aldhamen YA, Godbehere-Roosa S, Seregin SS, Kousa YA, Amalfitano A. Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice. Malaria Journal. 11: 209. PMID 22720732 DOI: 10.1186/1475-2875-11-209 |
0.814 |
|
| 2012 |
Seregin SS, Aldhamen YA, Rastall DP, Godbehere S, Amalfitano A. Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice. Vaccine. 30: 1492-501. PMID 22200503 DOI: 10.1016/J.Vaccine.2011.12.064 |
0.785 |
|
| 2011 |
Aldhamen YA, Seregin SS, Amalfitano A. Immune recognition of gene transfer vectors: focus on adenovirus as a paradigm. Frontiers in Immunology. 2: 40. PMID 22566830 DOI: 10.3389/Fimmu.2011.00040 |
0.789 |
|
| 2011 |
Schuldt NJ, Aldhamen YA, Appledorn DM, Seregin SS, Kousa Y, Godbehere S, Amalfitano A. Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses. Plos One. 6: e24147. PMID 21912619 DOI: 10.1371/Journal.Pone.0024147 |
0.824 |
|
| 2011 |
Seregin SS, Aldhamen YA, Appledorn DM, Aylsworth CF, Godbehere S, Liu CJ, Quiroga D, Amalfitano A. TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo. Plos One. 6: e22064. PMID 21760953 DOI: 10.1371/Journal.Pone.0022064 |
0.845 |
|
| 2011 |
Seregin SS, Aldhamen YA, Appledorn DM, Zehnder J, Voss T, Godbehere S, Amalfitano A. Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice. Human Gene Therapy. 22: 1083-94. PMID 21388344 DOI: 10.1089/Hum.2010.218 |
0.801 |
|
| 2011 |
Aldhamen YA, Appledorn DM, Seregin SS, Liu CJ, Schuldt NJ, Godbehere S, Amalfitano A. Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Journal of Immunology (Baltimore, Md. : 1950). 186: 722-32. PMID 21149608 DOI: 10.4049/Jimmunol.1002105 |
0.846 |
|
| 2011 |
Appledorn DM, Aldhamen YA, Godbehere S, Seregin SS, Amalfitano A. Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and systemic cell-mediated responses against HIV antigens despite preexisting Ad5 immunity. Clinical and Vaccine Immunology : Cvi. 18: 150-60. PMID 21084461 DOI: 10.1128/Cvi.00341-10 |
0.829 |
|
| 2010 |
Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. Blood. 116: 1669-77. PMID 20511542 DOI: 10.1182/Blood-2010-03-276949 |
0.814 |
|
| 2010 |
Appledorn DM, Aldhamen YA, Depas W, Seregin SS, Liu CJ, Schuldt N, Quach D, Quiroga D, Godbehere S, Zlatkin I, Kim S, McCormick JJ, Amalfitano A. A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. Plos One. 5: e9579. PMID 20221448 DOI: 10.1371/Journal.Pone.0009579 |
0.822 |
|
| 2009 |
Seregin SS, Aldhamen YA, Appledorn DM, Schuldt NJ, McBride AJ, Bujold M, Godbehere SS, Amalfitano A. CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Therapy. 16: 1245-59. PMID 19554032 DOI: 10.1038/Gt.2009.77 |
0.834 |
|
| 2009 |
Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 685-96. PMID 19174760 DOI: 10.1038/Mt.2008.297 |
0.821 |
|
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