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Shan Zha, Ph.D. - Publications

Affiliations: 
1998-2004 Pharmacology and Molecular Sciences Johns Hopkins University, Baltimore, MD 
 2004-2009 Molecular Genetics Harvard - Boston Children's Hospital 
 2009- Institute for Cancer Genetics Columbia University College of Physicians and Surgeons, New York, NY, United States 
Area:
DNA repair, Oncology, Molecular Biology, Pharmacology
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Year Citation  Score
2024 Zhang H, Zha S. The dynamics and regulation of PARP1 and PARP2 in response to DNA damage and during replication. Dna Repair. 140: 103690. PMID 38823186 DOI: 10.1016/j.dnarep.2024.103690  0.408
2024 Lin X, Leung KSK, Wolfe KF, Lee BJ, Zha S. XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites. Biorxiv : the Preprint Server For Biology. PMID 38798615 DOI: 10.1101/2024.05.14.594230  0.433
2024 Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. Biorxiv : the Preprint Server For Biology. PMID 38559022 DOI: 10.1101/2024.03.12.584665  0.389
2023 Wu-Baer F, Wong M, Tschoe L, Lin CS, Jiang W, Zha S, Baer R. ATM/ATR Phosphorylation of CtIP on Its Conserved Sae2-like Domain Is Required for Genotoxin-Induced DNA Resection but Dispensable for Animal Development. Cells. 12. PMID 38067190 DOI: 10.3390/cells12232762  0.468
2023 Li Z, Duan S, Hua X, Xu X, Li Y, Menolfi D, Zhou H, Lu C, Zha S, Goff SP, Zhang Z. Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. Nature. 623: 643-651. PMID 37938774 DOI: 10.1038/s41586-023-06711-3  0.326
2023 Cimprich KA, Li GM, Demaria S, Gekara NO, Zha S, Chen Q. The crosstalk between DNA repair and immune responses. Molecular Cell. 83: 3582-3587. PMID 37863025 DOI: 10.1016/j.molcel.2023.09.022  0.344
2023 Shao Z, Lee BJ, Zhang H, Lin X, Li C, Jiang W, Chirathivat N, Gershik S, Shen MM, Baer R, Zha S. Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301972120. PMID 37487079 DOI: 10.1073/pnas.2301972120  0.437
2023 Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Nature Communications. 14: 3618. PMID 37336885 DOI: 10.1038/s41467-023-39332-5  0.393
2023 Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, et al. Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination. Molecular Cell. PMID 37311462 DOI: 10.1016/j.molcel.2023.05.026  0.359
2023 Zhu Y, Jiang W, Lee BJ, Li A, Gershik S, Zha S. Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221894120. PMID 37307443 DOI: 10.1073/pnas.2221894120  0.444
2023 Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Biorxiv : the Preprint Server For Biology. PMID 37292881 DOI: 10.1101/2023.05.26.542515  0.378
2023 Zagelbaum J, Schooley A, Zhao J, Schrank BR, Callen E, Zha S, Gottesman ME, Nussenzweig A, Rabadan R, Dekker J, Gautier J. Author Correction: Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature Structural & Molecular Biology. PMID 37059902 DOI: 10.1038/s41594-023-00994-w  0.368
2023 Langelier MF, Lin X, Zha S, Pascal JM. Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Science Advances. 9: eadf7175. PMID 36961901 DOI: 10.1126/sciadv.adf7175  0.395
2022 Zagelbaum J, Schooley A, Zhao J, Schrank BR, Callen E, Zha S, Gottesman ME, Nussenzweig A, Rabadan R, Dekker J, Gautier J. Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature Structural & Molecular Biology. PMID 36564591 DOI: 10.1038/s41594-022-00893-6  0.399
2022 Zhang H, Lin X, Zha S. Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging. Biochemical Society Transactions. 50: 1169-1177. PMID 35959996 DOI: 10.1042/BST20220366  0.363
2022 Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S. PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites. Nucleic Acids Research. PMID 35349716 DOI: 10.1093/nar/gkac188  0.348
2021 Menolfi D, Zha S. DNA-PKcs kinase activity orchestrates both end-processing and end-ligation. Trends in Cell Biology. 32: 91-93. PMID 34953661 DOI: 10.1016/j.tcb.2021.12.002  0.4
2021 Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, ... Zha S, et al. DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34521752 DOI: 10.1073/pnas.2105440118  0.456
2021 Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW. XRCC1 prevents toxic PARP1 trapping during DNA base excision repair. Molecular Cell. PMID 34102106 DOI: 10.1016/j.molcel.2021.05.009  0.434
2021 Tao Y, Aparicio T, Li M, Leong KW, Zha S, Gautier J. Inhibition of DNA replication initiation by silver nanoclusters. Nucleic Acids Research. PMID 33905520 DOI: 10.1093/nar/gkab271  0.425
2021 Zha S, Shao Z, Zhu Y. The plié by DNA-PK: dancing on DNA. Molecular Cell. 81: 644-646. PMID 33606972 DOI: 10.1016/j.molcel.2021.01.025  0.362
2021 Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S. FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 33536256 DOI: 10.4049/jimmunol.2000967  0.39
2020 Milanovic M, Houghton LM, Menolfi D, Lee JH, Yamamoto K, Li Y, Lee BJ, Xu J, Estes VM, Wang D, McKinnon PJ, Paull TT, Zha S. The cancer-associated ATM R3008H mutation reveals the link between ATM activation and its exchange. Cancer Research. PMID 33239428 DOI: 10.1158/0008-5472.CAN-20-2447  0.632
2020 Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S. CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining. Proceedings of the National Academy of Sciences of the United States of America. PMID 32989150 DOI: 10.1073/pnas.2010972117  0.424
2020 Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S. Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo. Nucleic Acids Research. PMID 32890402 DOI: 10.1093/Nar/Gkaa718  0.515
2020 Crowe JL, Wang XS, Shao Z, Lee BJ, Estes VM, Zha S. DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. PMID 32868446 DOI: 10.1073/Pnas.2007455117  0.553
2020 Wang XS, Lee BJ, Zha S. The recent advances in non-homologous end-joining through the lens of lymphocyte development. Dna Repair. 94: 102874. PMID 32623318 DOI: 10.1016/J.Dnarep.2020.102874  0.592
2020 Liu X, Liu T, Shang Y, Dai P, Zhang W, Lee BJ, Huang M, Yang D, Wu Q, Liu LD, Zheng X, Zhou BO, Dong J, Yeap LS, Hu J, ... ... Zha S, et al. ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells. Cell Research. PMID 32355287 DOI: 10.1038/S41422-020-0328-3  0.551
2020 Shao Z, Flynn RA, Crowe JL, Zhu Y, Liang J, Jiang W, Aryan F, Aoude P, Bertozzi CR, Estes VM, Lee BJ, Bhagat G, Zha S, Calo E. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature. PMID 32103174 DOI: 10.1038/S41586-020-2041-2  0.528
2020 Menolfi D, Zha S. ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion. Cell & Bioscience. 10: 8. PMID 32015826 DOI: 10.1186/S13578-020-0376-X  0.543
2019 Scuoppo C, Zha S. LMO2 as a Biomarker for Hypersensitivity to Genotoxic Therapy. Cancer Cell. 36: 211-212. PMID 31526755 DOI: 10.1016/J.Ccell.2019.08.011  0.392
2019 Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S. Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination. Journal of Immunology (Baltimore, Md. : 1950). PMID 31101667 DOI: 10.4049/Jimmunol.1801657  0.548
2019 Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S. CtIP is essential for early B cell proliferation and development in mice. The Journal of Experimental Medicine. PMID 31097467 DOI: 10.1084/Jem.20181139  0.457
2019 Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen WF, Zha S, Vuong BQ, Chaudhuri J. Cutting Edge: ATM Influences Germinal Center Integrity. Journal of Immunology (Baltimore, Md. : 1950). PMID 31028119 DOI: 10.4049/Jimmunol.1801033  0.695
2019 Menolfi D, Zha S. ATM, DNA-PKcs and ATR: shaping development through the regulation of the DNA damage responses Genome Instability & Disease. 1: 47-68. DOI: 10.1007/S42764-019-00003-9  0.409
2018 Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S. Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA. Nature Communications. 9: 5351. PMID 30559436 DOI: 10.1038/S41467-018-07798-3  0.519
2018 Tal E, Alfo M, Zha S, Barzilai A, De Zeeuw CI, Ziv Y, Shiloh Y. Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype. Dna Repair. PMID 30348496 DOI: 10.1016/j.dnarep.2018.10.001  0.307
2018 Billing D, Horiguchi M, Wu-Baer F, Taglialatela A, Leuzzi G, Nanez SA, Jiang W, Zha S, Szabolcs M, Lin CS, Ciccia A, Baer R. The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection. Molecular Cell. PMID 30244837 DOI: 10.1016/J.Molcel.2018.08.016  0.373
2018 Crowe JL, Shao Z, Wang XS, Wei PC, Jiang W, Lee BJ, Estes VM, Alt FW, Zha S. Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. PMID 30072430 DOI: 10.1073/Pnas.1808490115  0.651
2018 Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, ... ... Zha S, et al. MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Molecular Cell. PMID 30017584 DOI: 10.1016/J.Molcel.2018.06.018  0.716
2018 Schrader A, Crispatzu G, Oberbeck S, Mayer P, Pützer S, von Jan J, Vasyutina E, Warner K, Weit N, Pflug N, Braun T, Andersson EI, Yadav B, Riabinska A, Maurer B, ... ... Zha S, et al. Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL. Nature Communications. 9: 697. PMID 29449575 DOI: 10.1038/S41467-017-02688-6  0.428
2017 Roohi J, Crowe J, Loredan D, Anyane-Yeboa K, Mansukhani MM, Omesi L, Levine J, Revah Politi A, Zha S. New diagnosis of atypical ataxia-telangiectasia in a 17-year-old boy with T-cell acute lymphoblastic leukemia and a novel ATM mutation. Journal of Human Genetics. PMID 28123174 DOI: 10.1038/Jhg.2017.6  0.353
2017 Liu X, Shao Z, Jiang W, Lee BJ, Zha S. PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice. Nature Communications. 8: 13816. PMID 28051062 DOI: 10.1038/Ncomms13816  0.542
2016 Zhou Y, Lee JH, Jiang W, Crowe JL, Zha S, Paull TT. Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM. Molecular Cell. PMID 27939942 DOI: 10.1016/J.Molcel.2016.11.004  0.558
2016 Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock CJ, Li C, Lee BJ, Loredan DG, Jiang W, Vindigni A, Wang D, Rabadan R, Zha S. Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors. Elife. 5. PMID 27304073 DOI: 10.7554/Elife.14709  0.634
2016 Li T, Liu X, Jiang L, Manfredi J, Zha S, Gu W. Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging. Oncotarget. PMID 26943586 DOI: 10.18632/Oncotarget.7864  0.442
2016 Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock CJ, Li C, Lee BJ, Loredan DG, Jiang W, Vindigni A, Wang D, Rabadan R, Zha S. Author response: Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors Elife. DOI: 10.7554/Elife.14709.020  0.543
2015 Pinkney KA, Jiang W, Lee BJ, Loredan DG, Li C, Bhagat G, Zha S. Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas. Journal of Hematology & Oncology. 8: 94. PMID 26219558 DOI: 10.1186/S13045-015-0191-8  0.369
2015 Jiang W, Crowe JL, Liu X, Nakajima S, Wang Y, Li C, Lee BJ, Dubois RL, Liu C, Yu X, Lan L, Zha S. Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining. Molecular Cell. 58: 172-85. PMID 25818648 DOI: 10.1016/J.Molcel.2015.02.024  0.539
2015 Jiang W, Lee BJ, Li C, Dubois RL, Gostissa M, Alt FW, Zha S. Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency. Blood. 125: 2665-8. PMID 25721125 DOI: 10.1182/Blood-2015-01-622621  0.545
2015 Yamamoto K, Lee BJ, Li C, Dubois RL, Hobeika E, Bhagat G, Zha S. Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice. Leukemia. 29: 1414-24. PMID 25676421 DOI: 10.1038/Leu.2015.41  0.636
2015 Xing M, Yang M, Huo W, Feng F, Wei L, Jiang W, Ning S, Yan Z, Li W, Wang Q, Hou M, Dong C, Guo R, Gao G, Ji J, ... Zha S, et al. Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nature Communications. 6: 6233. PMID 25670504 DOI: 10.1038/Ncomms7233  0.512
2014 Avagyan S, Churchill M, Yamamoto K, Crowe JL, Li C, Lee BJ, Zheng T, Mukherjee S, Zha S. Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency. Blood. 124: 1622-5. PMID 25075129 DOI: 10.1182/Blood-2014-05-574863  0.636
2013 Rass E, Chandramouly G, Zha S, Alt FW, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. The Journal of Biological Chemistry. 288: 7086-95. PMID 23355489 DOI: 10.1074/Jbc.M112.445825  0.638
2013 Oksenych V, Kumar V, Liu X, Guo C, Schwer B, Zha S, Alt FW. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining. Proceedings of the National Academy of Sciences of the United States of America. 110: 2234-9. PMID 23345432 DOI: 10.1073/Pnas.1222573110  0.744
2012 Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, Lin CS, Ludwig T, Bakkenist CJ, Zha S. Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. The Journal of Cell Biology. 198: 305-13. PMID 22869596 DOI: 10.1083/Jcb.201204098  0.719
2012 Liu X, Jiang W, Dubois RL, Yamamoto K, Wolner Z, Zha S. Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development. Proceedings of the National Academy of Sciences of the United States of America. 109: 3903-8. PMID 22355127 DOI: 10.1073/Pnas.1120160109  0.721
2012 Boboila C, Oksenych V, Gostissa M, Wang JH, Zha S, Zhang Y, Chai H, Lee CS, Jankovic M, Saez LM, Nussenzweig MC, McKinnon PJ, Alt FW, Schwer B. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1). Proceedings of the National Academy of Sciences of the United States of America. 109: 2473-8. PMID 22308491 DOI: 10.1073/Pnas.1121470109  0.8
2011 Gutierrez A, Kentsis A, Sanda T, Holmfeldt L, Chen SC, Zhang J, Protopopov A, Chin L, Dahlberg SE, Neuberg DS, Silverman LB, Winter SS, Hunger SP, Sallan SE, Zha S, et al. The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. Blood. 118: 4169-73. PMID 21878675 DOI: 10.1182/Blood-2010-11-318873  0.535
2011 Liu X, Zha S. ATMIN: a new tumor suppressor in developing B cells. Cancer Cell. 19: 569-70. PMID 21575856 DOI: 10.1016/J.Ccr.2011.05.002  0.349
2011 Zha S, Jiang W, Fujiwara Y, Patel H, Goff PH, Brush JW, Dubois RL, Alt FW. Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions. Proceedings of the National Academy of Sciences of the United States of America. 108: 2028-33. PMID 21245310 DOI: 10.1073/Pnas.1019293108  0.675
2011 Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature. 469: 250-4. PMID 21160472 DOI: 10.1038/Nature09604  0.799
2010 Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW. ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification. The Journal of Experimental Medicine. 207: 1369-80. PMID 20566716 DOI: 10.1084/Jem.20100285  0.776
2010 Rucci F, Notarangelo LD, Fazeli A, Patrizi L, Hickernell T, Paganini T, Coakley KM, Detre C, Keszei M, Walter JE, Feldman L, Cheng HL, Poliani PL, Wang JH, Balter BB, ... ... Zha S, et al. Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome. Proceedings of the National Academy of Sciences of the United States of America. 107: 3024-9. PMID 20133615 DOI: 10.1073/Pnas.0914865107  0.565
2010 Gutierrez A, Kentsis A, Sanda T, Etchin J, Protopopov A, Zhang J, Chin L, Silverman LB, Winter S, Hunger S, Sallan SE, Zha S, Alt F, Look AT. The BCL11B Tumor Suppressor Is Mutated In Human T-Cell Acute Lymphoblastic Leukemia Blood. 116: 4177-4177. DOI: 10.1182/Blood.V116.21.4177.4177  0.537
2009 Zha S, Boboila C, Alt FW. Mre11: roles in DNA repair beyond homologous recombination. Nature Structural & Molecular Biology. 16: 798-800. PMID 19654615 DOI: 10.1038/Nsmb0809-798  0.781
2009 Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Molecular Cell. 34: 285-97. PMID 19450527 DOI: 10.1016/J.Molcel.2009.04.025  0.673
2008 Li G, Alt FW, Cheng HL, Brush JW, Goff PH, Murphy MM, Franco S, Zhang Y, Zha S. Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination. Molecular Cell. 31: 631-40. PMID 18775323 DOI: 10.1016/J.Molcel.2008.07.017  0.577
2008 Zha S, Sekiguchi J, Brush JW, Bassing CH, Alt FW. Complementary functions of ATM and H2AX in development and suppression of genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 105: 9302-6. PMID 18599436 DOI: 10.1073/Pnas.0803520105  0.618
2007 Zha S, Alt FW, Cheng HL, Brush JW, Li G. Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 4518-23. PMID 17360556 DOI: 10.1073/Pnas.0611734104  0.666
2006 Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, et al. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Molecular Cell. 21: 201-14. PMID 16427010 DOI: 10.1016/J.Molcel.2006.01.005  0.785
2005 Zha S, Isaacs WB. A nonclassic CCAAT enhancer element binding protein binding site contributes to alpha-methylacyl-CoA racemase expression in prostate cancer. Molecular Cancer Research : McR. 3: 110-8. PMID 15755877 DOI: 10.1158/1541-7786.Mcr-04-0178  0.485
2005 Zha S, Ferdinandusse S, Hicks JL, Denis S, Dunn TA, Wanders RJ, Luo J, De Marzo AM, Isaacs WB. Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. The Prostate. 63: 316-23. PMID 15599942 DOI: 10.1002/Pros.20177  0.437
2004 Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB, De Marzo AM. Cyclooxygenases in cancer: progress and perspective. Cancer Letters. 215: 1-20. PMID 15374627 DOI: 10.1016/J.Canlet.2004.06.014  0.455
2004 Rogers CG, Yan G, Zha S, Gonzalgo ML, Isaacs WB, Luo J, De Marzo AM, Nelson WG, Pavlovich CP. Prostate cancer detection on urinalysis for alpha methylacyl coenzyme a racemase protein. The Journal of Urology. 172: 1501-3. PMID 15371879 DOI: 10.1097/01.Ju.0000137659.53129.14  0.429
2003 Zha S, Ferdinandusse S, Denis S, Wanders RJ, Ewing CM, Luo J, De Marzo AM, Isaacs WB. Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer. Cancer Research. 63: 7365-76. PMID 14612535  0.427
2003 De Marzo AM, Meeker AK, Zha S, Luo J, Nakayama M, Platz EA, Isaacs WB, Nelson WG. Human prostate cancer precursors and pathobiology. Urology. 62: 55-62. PMID 14607218 DOI: 10.1016/J.Urology.2003.09.053  0.46
2002 Luo J, Zha S, Gage WR, Dunn TA, Hicks JL, Bennett CJ, Ewing CM, Platz EA, Ferdinandusse S, Wanders RJ, Trent JM, Isaacs WB, De Marzo AM. Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer. Cancer Research. 62: 2220-6. PMID 11956072  0.376
2001 Zha S, Gage WR, Sauvageot J, Saria EA, Putzi MJ, Ewing CM, Faith DA, Nelson WG, De Marzo AM, Isaacs WB. Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma. Cancer Research. 61: 8617-23. PMID 11751373  0.394
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