Christine M. Eischen - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Cell Biology, Molecular Biology

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mitra R, Adams CM, Eischen CM. Decoding the lncRNAome Across Diverse Cellular Stresses Reveals Core p53-effector Pan-cancer Suppressive lncRNAs. Cancer Research Communications. 3: 842-859. PMID 37377895 DOI: 10.1158/2767-9764.CRC-22-0473  0.331
2023 Adams CM, Mitra R, Xiao Y, Michener P, Palazzo J, Chao A, Gour J, Cassel J, Salvino JM, Eischen CM. Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer. Cancer Discovery. PMID 36734633 DOI: 10.1158/2159-8290.CD-22-1131  0.418
2022 Grieb BC, Eischen CM. MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging. Biology. 11. PMID 35741402 DOI: 10.3390/biology11060881  0.304
2021 Porazzi P, Petruk S, Pagliaroli L, De Dominici M, Deming D, Puccetti MV, Kushinsky S, Kumar G, Minieri V, Barbieri E, Deliard S, Grande A, Trizzino M, Gardini A, Canaani E, ... ... Eischen CM, et al. Targeting chemotherapy to de-condensed H3K27me3-marked chromatin of AML cells enhances leukemia suppression. Cancer Research. PMID 34903608 DOI: 10.1158/0008-5472.CAN-21-1297  0.318
2020 Wohlberedt K, Klusmann I, Derevyanko PK, Henningsen K, Choo JAMY, Manzini V, Magerhans A, Giansanti C, Eischen CM, Jochemsen AG, Dobbelstein M. Mdm4 supports DNA replication in a p53-independent fashion. Oncogene. PMID 32427989 DOI: 10.1038/S41388-020-1325-1  0.515
2020 Thomas LR, Adams CM, Fesik SW, Eischen CM, Tansey WP. Targeting MYC through WDR5. Molecular & Cellular Oncology. 7: 1709388. PMID 32158922 DOI: 10.1080/23723556.2019.1709388  0.368
2020 Mitra R, Adams CM, Jiang W, Greenawalt E, Eischen CM. Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival. Nature Communications. 11: 968. PMID 32080184 DOI: 10.1038/S41467-020-14713-2  0.406
2020 Qin G, Mallik S, Mitra R, Li A, Jia P, Eischen CM, Zhao Z. MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors. Scientific Reports. 10: 852. PMID 31965022 DOI: 10.1038/S41598-020-57834-W  0.33
2019 Thomas LR, Adams CM, Wang J, Weissmiller AM, Creighton J, Lorey SL, Liu Q, Fesik SW, Eischen CM, Tansey WP. Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance. Proceedings of the National Academy of Sciences of the United States of America. PMID 31767764 DOI: 10.1073/Pnas.1910391116  0.404
2019 Stier MT, Mitra R, Nyhoff LE, Goleniewska K, Zhang J, Puccetti MV, Casanova HC, Seegmiller AC, Newcomb DC, Kendall PL, Eischen CM, Peebles RS. IL-33 Is a Cell-Intrinsic Regulator of Fitness during Early B Cell Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 31391233 DOI: 10.4049/Jimmunol.1900408  0.315
2019 Puccetti MV, Adams CM, Dan TD, Palagani A, Simone BA, DeAngelis T, Eischen CM, Simone NL. miR-21 is required for hematopoietic cell viability following radiation exposure. International Journal of Radiation Oncology, Biology, Physics. PMID 31039423 DOI: 10.1016/J.Ijrobp.2019.04.020  0.3
2019 Puccetti MV, Adams CM, Kushinsky S, Eischen CM. Smarcal1 and Zranb3 protect replication forks from Myc-induced DNA replication stress. Cancer Research. PMID 30610086 DOI: 10.1158/0008-5472.Can-18-2705  0.444
2018 Adams CM, Clark-Garvey S, Porcu P, Eischen CM. Targeting the Bcl-2 Family in B Cell Lymphoma. Frontiers in Oncology. 8: 636. PMID 30671383 DOI: 10.3389/Fonc.2018.00636  0.358
2018 Greenawalt EJ, Edmonds MD, Jain N, Adams CM, Mitra R, Eischen CM. Targeting of SGK1 by miR-576-3p inhibits lung adenocarcinoma migration and invasion. Molecular Cancer Research : McR. PMID 30257988 DOI: 10.1158/1541-7786.Mcr-18-0364  0.341
2018 Olivos DJ, Perrien DS, Hooker A, Cheng YH, Fuchs RK, Hong JM, Bruzzaniti A, Chun K, Eischen CM, Kacena MA, Mayo LD. The proto-oncogene function of Mdm2 in bone. Journal of Cellular Biochemistry. PMID 30011084 DOI: 10.1002/Jcb.27133  0.338
2017 Mitra R, Chen X, Greenawalt EJ, Maulik U, Jiang W, Zhao Z, Eischen CM. Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition. Nature Communications. 8: 1604. PMID 29150601 DOI: 10.1038/S41467-017-01781-0  0.311
2017 Adams CM, Mitra R, Gong J, Eischen CM. Non-Hodgkin and Hodgkin lymphomas select for overexpression of BCLW. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28855351 DOI: 10.1158/1078-0432.Ccr-17-1144  0.344
2017 Feeley K, Adams CM, Mitra R, Eischen CM. Mdm2 is required for survival and growth of p53-deficient cancer cells. Cancer Research. PMID 28576884 DOI: 10.1158/0008-5472.Can-17-0809  0.545
2017 Moyo TK, Wilson CS, Moore DJ, Eischen CM. Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition. Oncogene. PMID 28368423 DOI: 10.1038/Onc.2017.95  0.368
2017 Adams CM, Kim AS, Mitra R, Choi JK, Gong JZ, Eischen CM. BCL-W has a fundamental role in B cell survival and lymphomagenesis. The Journal of Clinical Investigation. PMID 28094768 DOI: 10.1172/Jci89486  0.415
2017 Adams CM, Mitra R, Gong JZ, Kim AS, Choi JK, Eischen CM. Abstract 02: BCL-W significantly contributes to B-cell lymphoma survival and development Clinical Cancer Research. 23: 2-2. DOI: 10.1158/1557-3265.Hemmal17-02  0.419
2016 Eischen CM. Role of MDM2 and MDMX in DNA repair. Journal of Molecular Cell Biology. PMID 27932484 DOI: 10.1093/Jmcb/Mjw052  0.548
2016 Puccetti MV, Fischer MA, Arrate MP, Boyd KL, Duszynski RJ, Bétous R, Cortez D, Eischen CM. Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution. Oncogene. PMID 27797382 DOI: 10.1038/Onc.2016.408  0.441
2016 Liu S, Mitra R, Zhao MM, Fan W, Eischen CM, Yin F, Zhao Z. The potential roles of long non-coding RNAs (lncRNAs) in glioblastoma development. Molecular Cancer Therapeutics. PMID 27784795 DOI: 10.1158/1535-7163.Mct-16-0320  0.352
2016 Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, ... ... Eischen CM, et al. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer. Oncotarget. PMID 27590350 DOI: 10.18632/Oncotarget.11718  0.368
2016 Eischen CM. Genome Stability Requires p53. Cold Spring Harbor Perspectives in Medicine. 6. PMID 27252396 DOI: 10.1101/Cshperspect.A026096  0.423
2016 Thompson MA, Edmonds MD, Liang S, McClintock-Treep S, Wang X, Li S, Eischen CM. miR-31 and miR-17-5p levels change during transformation of follicular lymphoma. Human Pathology. 50: 118-26. PMID 26997445 DOI: 10.1016/J.Humpath.2015.11.011  0.349
2016 Adams CM, Eischen CM. Histone deacetylase inhibition reveals a tumor-suppressive function of MYC-regulated miRNA in breast and lung carcinoma. Cell Death and Differentiation. PMID 26915294 DOI: 10.1038/Cdd.2016.9  0.392
2016 Adams CM, Hiebert SW, Eischen CM. Abstract A24: HDAC inhibition unmasks a microRNA-mediated mechanism of tumor suppression Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A24  0.396
2016 Edmonds MD, Boyd KL, Moyo TK, Mitra R, Duszynski RJ, Arrate MP, Chen X, Zhao Z, Blackwell TS, Eischen CM. Abstract LB-168: MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-168  0.302
2016 Taylor A, Adams C, Zhang X, Gennaro V, Cotney J, Shadel G, Cameron C, Eischen C, McMahon S. Abstract 1256: Multi-focal control of mitochondrial gene expression by oncogenic MYC provides effective therapeutic targets in cancer Cancer Research. 76: 1256-1256. DOI: 10.1158/1538-7445.Am2016-1256  0.369
2015 Adams CM, Hiebert SW, Eischen CM. Myc induces miRNA-mediated apoptosis in response to HDAC inhibition in hematologic malignancies. Cancer Research. PMID 26676759 DOI: 10.1158/0008-5472.Can-15-1751  0.426
2015 Poole LA, Zhao R, Glick GG, Lovejoy CA, Eischen CM, Cortez D. SMARCAL1 maintains telomere integrity during DNA replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 26578802 DOI: 10.1073/Pnas.1510750112  0.436
2015 Thomas LR, Foshage AM, Weissmiller AM, Popay TM, Grieb BC, Qualls SJ, Ng V, Carboneau B, Lorey S, Eischen CM, Tansey WP. Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif. Oncogene. PMID 26522729 DOI: 10.1038/Onc.2015.416  0.406
2015 Tonsing-Carter E, Bailey BJ, Saadatzadeh MR, Ding J, Wang H, Sinn AL, Peterman KM, Spragins TK, Silver JM, Sprouse AA, Georgiadis TM, Gunter TZ, Long EC, Minto RE, Marchal CC, ... ... Eischen CM, et al. Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model. Molecular Cancer Therapeutics. PMID 26494859 DOI: 10.1158/1535-7163.Mct-15-0237  0.422
2015 McGirt LY, Jia P, Baerenwald DA, Duszynski RJ, Dahlman KB, Zic JA, Zwerner JP, Hucks D, Dave U, Zhao Z, Eischen CM. Whole genome sequencing reveals oncogenic mutations in mycosis fungoides. Blood. PMID 26082451 DOI: 10.1182/Blood-2014-11-611194  0.37
2015 Carrillo AM, Hicks M, Khabele D, Eischen CM. Pharmacologically increasing Mdm2 inhibits DNA repair and cooperates with genotoxic agents to kill p53 inactivated ovarian cancer cells. Molecular Cancer Research : McR. PMID 25964101 DOI: 10.1158/1541-7786.Mcr-15-0089  0.553
2015 Mitra R, Lin CC, Eischen CM, Bandyopadhyay S, Zhao Z. Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study. Rna (New York, N.Y.). 21: 1055-65. PMID 25852169 DOI: 10.1261/Rna.048132.114  0.401
2015 Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, et al. Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC. Molecular Cell. 58: 440-52. PMID 25818646 DOI: 10.2210/Pdb6Dak/Pdb  0.378
2015 Carrillo AM, Bouska A, Arrate MP, Eischen CM. Mdmx promotes genomic instability independent of p53 and Mdm2. Oncogene. 34: 846-56. PMID 24608433 DOI: 10.1038/Onc.2014.27  0.768
2015 Adams CM, Eischen CM. Abstract A14: Epigenetic alterations reactivate a novel mechanism of Myc-induced apoptosis Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A14  0.423
2014 Adams CM, Eischen CM. Cell survival is dicey without Dicer. Molecular & Cellular Oncology. 1. PMID 25558471 DOI: 10.4161/23723548.2014.961825  0.368
2014 Edmonds MD, Eischen CM. Differences in miRNA expression in early stage lung adenocarcinomas that did and did not relapse. Plos One. 9: e101802. PMID 25028925 DOI: 10.1371/Journal.Pone.0101802  0.306
2014 Mitra R, Edmonds MD, Sun J, Zhao M, Yu H, Eischen CM, Zhao Z. Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancer. Rna (New York, N.Y.). 20: 1356-68. PMID 25024357 DOI: 10.1261/Rna.042754.113  0.305
2014 Grieb BC, Chen X, Eischen CM. MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival. Molecular Cancer Research : McR. 12: 1216-24. PMID 24866769 DOI: 10.1158/1541-7786.Mcr-14-0069  0.346
2014 Adams CM, Eischen CM. Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer. Cancer Research. 74: 3923-34. PMID 24840646 DOI: 10.1158/0008-5472.Can-13-1866  0.497
2014 Grieb BC, Gramling MW, Arrate MP, Chen X, Beauparlant SL, Haines DS, Xiao H, Eischen CM. Oncogenic protein MTBP interacts with MYC to promote tumorigenesis. Cancer Research. 74: 3591-602. PMID 24786788 DOI: 10.1158/0008-5472.Can-13-2149  0.385
2014 Eischen CM, Lozano G. The Mdm network and its regulation of p53 activities: a rheostat of cancer risk. Human Mutation. 35: 728-37. PMID 24488925 DOI: 10.1002/Humu.22524  0.484
2014 Carrillo AM, Bouska A, Arrate MP, Eischen CM. Mdmx promotes genomic instability independent of p53 and Mdm2 Oncogene. DOI: 10.1038/onc.2014.27  0.758
2013 Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. Plos One. 8: e80228. PMID 24282525 DOI: 10.1371/Journal.Pone.0080228  0.533
2013 Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. Plos One. 8: e68915. PMID 23894374 DOI: 10.1371/Journal.Pone.0068915  0.425
2013 Melo AN, Bouska A, Arrate MP, Eischen CM. Abstract 1768: The oncogene Mdmx promotes genomic instability independent of p53. Cancer Research. 73: 1768-1768. DOI: 10.1158/1538-7445.Am2013-1768  0.571
2012 Melo AN, Eischen CM. Protecting the genome from mdm2 and mdmx. Genes & Cancer. 3: 283-90. PMID 23150761 DOI: 10.1177/1947601912454139  0.547
2012 Eischen CM, Boyd K. Decreased Mdm2 Expression Inhibits Tumor Development and Extends Survival Independent of Arf and Dependent on p53 Plos One. 7. PMID 23029416 DOI: 10.1371/Journal.Pone.0046148  0.512
2012 Anderson PD, McKissic SA, Logan M, Roh M, Franco OE, Wang J, Doubinskaia I, van der Meer R, Hayward SW, Eischen CM, Eltoum IE, Abdulkadir SA. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. The Journal of Clinical Investigation. 122: 1907-19. PMID 22484818 DOI: 10.1172/Jci58540  0.339
2012 Gramling MW, Eischen CM. Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis. Cell Death and Differentiation. 19: 1220-7. PMID 22301919 DOI: 10.1038/Cdd.2012.1  0.407
2012 Anderson PD, McKissic SA, Logan M, Roh M, Franco O, Wang J, Doubinskaia I, Meer Rvd, Hayward S, Eischen C, Eltoum IA, Abdulkadir SA. Abstract 2983: Nkx3.1 and c-Myc co-regulate shared target genes involved in prostate cancer Cancer Research. 72: 2983-2983. DOI: 10.1158/1538-7445.Am2012-2983  0.343
2011 Cho SH, Ahn AK, Bhargava P, Lee CH, Eischen CM, McGuinness O, Boothby M. Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family. Proceedings of the National Academy of Sciences of the United States of America. 108: 15972-7. PMID 21911376 DOI: 10.1073/Pnas.1017082108  0.362
2011 Lushnikova T, Bouska A, Odvody J, Dupont WD, Eischen CM. Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression. Oncogene. 30: 4622-31. PMID 21602883 DOI: 10.1038/Onc.2011.172  0.686
2011 Eischen CM. Decreased Mdm2 levels after DNA damage: antibody masking or protein degradation? Cell Cycle (Georgetown, Tex.). 10: 1347. PMID 21460638 DOI: 10.4161/Cc.10.9.15437  0.338
2011 Eischen CM. Abstract CN05-01: Targeting Mdm2 in DNA repair and chromosome instability. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-Cn05-01  0.542
2010 Arrate MP, Vincent T, Odvody J, Kar R, Jones SN, Eischen CM. MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival. Cancer Research. 70: 6083-92. PMID 20587524 DOI: 10.1158/0008-5472.Can-09-4736  0.406
2010 Odvody J, Vincent T, Arrate MP, Grieb B, Wang S, Garriga J, Lozano G, Iwakuma T, Haines DS, Eischen CM. A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis. Oncogene. 29: 3287-96. PMID 20305689 DOI: 10.1038/Onc.2010.82  0.536
2010 Sluss HK, Gannon H, Coles AH, Shen Q, Eischen CM, Jones SN. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis. Molecular Cancer Research : McR. 8: 216-22. PMID 20145032 DOI: 10.1158/1541-7786.Mcr-09-0324  0.561
2010 Post SM, Quintás-Cardama A, Terzian T, Smith C, Eischen CM, Lozano G. p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis. Oncogene. 29: 1260-9. PMID 19935700 DOI: 10.1038/Onc.2009.423  0.511
2009 Bouska A, Eischen CM. Murine double minute 2: p53-independent roads lead to genome instability or death. Trends in Biochemical Sciences. 34: 279-86. PMID 19447627 DOI: 10.1016/J.Tibs.2009.02.006  0.771
2009 Eischen CM, Lozano G. p53 and MDM2: antagonists or partners in crime? Cancer Cell. 15: 161-2. PMID 19249672 DOI: 10.1016/J.Ccr.2009.02.004  0.42
2009 Bouska A, Eischen CM. Mdm2 affects genome stability independent of p53. Cancer Research. 69: 1697-701. PMID 19244108 DOI: 10.1158/0008-5472.Can-08-3732  0.759
2009 Cho SH, Goenka S, Henttinen T, Gudapati P, Reinikainen A, Eischen CM, Lahesmaa R, Boothby M. PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells. Blood. 113: 2416-25. PMID 19147789 DOI: 10.1182/Blood-2008-03-144121  0.415
2008 Humbey O, Pimkina J, Zilfou JT, Jarnik M, Dominguez-Brauer C, Burgess DJ, Eischen CM, Murphy ME. The ARF tumor suppressor can promote the progression of some tumors. Cancer Research. 68: 9608-13. PMID 19047137 DOI: 10.1158/0008-5472.Can-08-2263  0.474
2008 Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL, Lawrence JB, Imbalzano AN, Jones SN. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. The Journal of Cell Biology. 181: 1055-63. PMID 18591425 DOI: 10.1083/Jcb.200802105  0.432
2008 Bouska A, Lushnikova T, Plaza S, Eischen CM. Mdm2 promotes genetic instability and transformation independent of p53. Molecular and Cellular Biology. 28: 4862-74. PMID 18541670 DOI: 10.1128/Mcb.01584-07  0.755
2008 Iwakuma T, Tochigi Y, Van Pelt CS, Caldwell LC, Terzian T, Parant JM, Chau GP, Koch JG, Eischen CM, Lozano G. Mtbp haploinsufficiency in mice increases tumor metastasis. Oncogene. 27: 1813-20. PMID 17906694 DOI: 10.1038/Sj.Onc.1210827  0.515
2008 Wang P, Lushnikova T, Odvody J, Greiner TC, Jones SN, Eischen CM. Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells Oncogene. 27: 1590-1598. PMID 17828300 DOI: 10.1038/Sj.Onc.1210788  0.536
2007 Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. The Journal of Biological Chemistry. 282: 1322-33. PMID 17110379 DOI: 10.1074/Jbc.M609612200  0.525
2006 Wang P, Greiner TC, Lushnikova T, Eischen CM. Decreased Mdm2 expression inhibits tumor development induced by loss of ARF. Oncogene. 25: 3708-18. PMID 16491126 DOI: 10.1038/Sj.Onc.1209411  0.467
2005 Alt JR, Bouska A, Fernandez MR, Cerny RL, Xiao H, Eischen CM. Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. The Journal of Biological Chemistry. 280: 18771-81. PMID 15734743 DOI: 10.1074/Jbc.M413387200  0.737
2004 Eischen CM, Alt JR, Wang P. Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development. Oncogene. 23: 8931-40. PMID 15467748 DOI: 10.1038/Sj.Onc.1208052  0.774
2003 Alt JR, Greiner TC, Cleveland JL, Eischen CM. Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis. The Embo Journal. 22: 1442-50. PMID 12628936 DOI: 10.1093/Emboj/Cdg133  0.771
2002 Dang J, Kuo ML, Eischen CM, Stepanova L, Sherr CJ, Roussel MF. The RING domain of Mdm2 can inhibit cell proliferation. Cancer Research. 62: 1222-30. PMID 11861407  0.401
2001 Eischen CM, Packham G, Nip J, Fee BE, Hiebert SW, Zambetti GP, Cleveland JL. Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 Oncogene. 20: 6983-6993. PMID 11704823 DOI: 10.1038/Sj.Onc.1204892  0.502
2001 Braun JS, Novak R, Murray PJ, Eischen CM, Susin SA, Kroemer G, Halle A, Weber JR, Tuomanen EI, Cleveland JL. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. The Journal of Infectious Diseases. 184: 1300-9. PMID 11679919 DOI: 10.1086/324013  0.336
2001 Eischen CM, Roussel MF, Korsmeyer SJ, Cleveland JL. Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. Molecular and Cellular Biology. 21: 7653-62. PMID 11604501 DOI: 10.1128/Mcb.21.22.7653-7662.2001  0.529
2001 Eischen CM, Woo D, Roussel MF, Cleveland JL. Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis. Molecular and Cellular Biology. 21: 5063-70. PMID 11438662 DOI: 10.1128/Mcb.21.15.5063-5070.2001  0.364
2001 Nip J, Strom DK, Eischen CM, Cleveland JL, Zambetti GP, Hiebert SW. E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation Oncogene. 20: 910-920. PMID 11314026 DOI: 10.1038/Sj.Onc.1204171  0.484
1999 Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes & Development. 13: 2658-69. PMID 10541552 DOI: 10.1101/Gad.13.20.2658  0.555
1998 Packham G, White EL, Eischen CM, Yang H, Parganas E, Ihle JN, Grillot DA, Zambetti GP, Nuñez G, Cleveland JL. Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies. Genes & Development. 12: 2475-87. PMID 9716401 DOI: 10.1101/Gad.12.16.2475  0.377
1998 Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes & Development. 12: 2424-33. PMID 9694806 DOI: 10.1101/Gad.12.15.2424  0.551
1997 Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, Earnshaw WC, Leibson PJ, Kaufmann SH. Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood. 90: 935-43. PMID 9242521 DOI: 10.1182/Blood.V90.3.935.935_935_943  0.348
1997 Eischen CM, Leibson PJ. The Fas pathway in apoptosis. Advances in Pharmacology (San Diego, Calif.). 41: 107-32. PMID 9204143 DOI: 10.1016/S1054-3589(08)61056-X  0.344
Show low-probability matches.